WO2022083913A1 - Système de cartouche et pompe à vis excentrique - Google Patents

Système de cartouche et pompe à vis excentrique Download PDF

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Publication number
WO2022083913A1
WO2022083913A1 PCT/EP2021/072334 EP2021072334W WO2022083913A1 WO 2022083913 A1 WO2022083913 A1 WO 2022083913A1 EP 2021072334 W EP2021072334 W EP 2021072334W WO 2022083913 A1 WO2022083913 A1 WO 2022083913A1
Authority
WO
WIPO (PCT)
Prior art keywords
cartridge
cartridge system
rotor
plug
stator
Prior art date
Application number
PCT/EP2021/072334
Other languages
German (de)
English (en)
Inventor
Robert Heizinger
Thomas Huber
Raphael Lichtnecker
Stephan OSWALD
Horst Kelsch
Felix Gruber
Angelo Schulz
Simon KASBÖCK
Original Assignee
Viscotec Pumpen- U. Dosiertechnik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viscotec Pumpen- U. Dosiertechnik Gmbh filed Critical Viscotec Pumpen- U. Dosiertechnik Gmbh
Priority to US18/033,026 priority Critical patent/US20230392594A1/en
Priority to DE112021005611.5T priority patent/DE112021005611A5/de
Priority to CN202180071792.XA priority patent/CN116529486A/zh
Publication of WO2022083913A1 publication Critical patent/WO2022083913A1/fr

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04CROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2/00Rotary-piston machines or pumps
    • F04C2/08Rotary-piston machines or pumps of intermeshing-engagement type, i.e. with engagement of co-operating members similar to that of toothed gearing
    • F04C2/10Rotary-piston machines or pumps of intermeshing-engagement type, i.e. with engagement of co-operating members similar to that of toothed gearing of internal-axis type with the outer member having more teeth or tooth-equivalents, e.g. rollers, than the inner member
    • F04C2/107Rotary-piston machines or pumps of intermeshing-engagement type, i.e. with engagement of co-operating members similar to that of toothed gearing of internal-axis type with the outer member having more teeth or tooth-equivalents, e.g. rollers, than the inner member with helical teeth
    • F04C2/1071Rotary-piston machines or pumps of intermeshing-engagement type, i.e. with engagement of co-operating members similar to that of toothed gearing of internal-axis type with the outer member having more teeth or tooth-equivalents, e.g. rollers, than the inner member with helical teeth the inner and outer member having a different number of threads and one of the two being made of elastic materials, e.g. Moineau type
    • F04C2/1073Rotary-piston machines or pumps of intermeshing-engagement type, i.e. with engagement of co-operating members similar to that of toothed gearing of internal-axis type with the outer member having more teeth or tooth-equivalents, e.g. rollers, than the inner member with helical teeth the inner and outer member having a different number of threads and one of the two being made of elastic materials, e.g. Moineau type where one member is stationary while the other member rotates and orbits
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04CROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2/00Rotary-piston machines or pumps
    • F04C2/08Rotary-piston machines or pumps of intermeshing-engagement type, i.e. with engagement of co-operating members similar to that of toothed gearing
    • F04C2/10Rotary-piston machines or pumps of intermeshing-engagement type, i.e. with engagement of co-operating members similar to that of toothed gearing of internal-axis type with the outer member having more teeth or tooth-equivalents, e.g. rollers, than the inner member
    • F04C2/107Rotary-piston machines or pumps of intermeshing-engagement type, i.e. with engagement of co-operating members similar to that of toothed gearing of internal-axis type with the outer member having more teeth or tooth-equivalents, e.g. rollers, than the inner member with helical teeth
    • F04C2/1071Rotary-piston machines or pumps of intermeshing-engagement type, i.e. with engagement of co-operating members similar to that of toothed gearing of internal-axis type with the outer member having more teeth or tooth-equivalents, e.g. rollers, than the inner member with helical teeth the inner and outer member having a different number of threads and one of the two being made of elastic materials, e.g. Moineau type
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04CROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C13/00Adaptations of machines or pumps for special use, e.g. for extremely high pressures

Definitions

  • the present invention relates to a cartridge system for an eccentric worm pump and an eccentric worm pump, in particular a 3D print head, with such a cartridge system.
  • Progressing cavity pumps include a stator and a rotor rotating in the stator.
  • a medium to be metered is conveyed by the interaction of the rotor with the stator in a longitudinal direction of the eccentric screw pump away from a drive device of the eccentric screw pump according to the endless piston principle.
  • the delivery volume per unit of time depends on the speed, size, pitch and geometry of the rotor.
  • a component is built up in layers from a liquid, powder or paste-like material or medium.
  • a liquid, powder or paste-like material or medium For example, if different formulations of the medium to be printed are tested, it is usually necessary to disassemble the entire progressing cavity pump, which is laborious and time-consuming, and to clean the components that come into contact with the medium, such as the rotor and the stator. It is therefore desirable for the eccentric screw pump to be cleaned as quickly and easily as possible.
  • one object of the present invention is to provide an exchangeable cartridge system for an eccentric screw pump.
  • a cartridge system for an eccentric screw pump e is proposed.
  • the cartridge system comprises a cartridge for receiving a medium to be metered, a stator provided on the cartridge, which interacts with a rotor unit of the eccentric screw pump e for metering the medium, and a plug movably mounted in the cartridge for fluid-tight sealing of the cartridge, the plug having a Rotor breakthrough includes, through which the rotor unit is out feasible.
  • the movably mounted stopper is provided in the cartridge prevents the medium to be metered from being contaminated.
  • all components in contact with the medium can be replaced by simply replacing the entire cartridge system. Contamination of the drive unit is not to be expected. This significantly simplifies the cleaning of the progressing cavity pump.
  • the progressing cavity pump preferably includes the rotor unit.
  • the rotor unit can also be part of the cartridge.
  • the rotor unit includes a flexible shaft or flex shaft, which is coupled to the drive device of the eccentric screw pump.
  • the flex shaft can also be referred to as a flexible shaft or cardan shaft.
  • the flex shaft can also be a flexible rod, in particular a plastic flexible rod, or be referred to as such.
  • the flex shaft can be made of a polyetheretherketone (PEEK), polyethylene (PE) or the like, for example.
  • a rotor is provided on the front side of the flexible shaft, which interacts with the stator.
  • the stator preferably comprises an elastically deformable inner part or elastomer part with a central opening.
  • the breakthrough preferably includes a helical or snail-shaped inner contour.
  • the rotatable rotor which includes a corresponding to the inner part screw-shaped or snail-shaped outer contour.
  • the eccentric worm pump also includes the previously mentioned drive device.
  • the rotor is driven via the flexible shaft by a drive unit, in particular an electric motor, of the drive device.
  • the drive unit drives a drive shaft of the drive device, which is coupled to the rotor unit.
  • the drive shaft can be rigidly connected to the rotor by means of the aforementioned flexible shaft or flex shaft.
  • the rotor unit preferably performs an eccentric movement in the rotor opening.
  • this is not mandatory.
  • a purely rotational movement could also be provided.
  • a joint or the aforementioned flex shaft is to be provided after stuffing, i.e. in the medium.
  • the cartridge is preferably cylindrical.
  • the cartridge is a disposable syringe.
  • the cartridge system is preferably a single-use item (EnglJ Disposable).
  • the cartridge system can also be used several times.
  • the cartridge preferably has a Luer lock connection on the front side. This makes it easy to connect a nozzle to the cartridge.
  • the cartridge can also be filled via the Luer-Lock connection.
  • the fact that the stator is “provided” on the cartridge can mean that the stator is firmly connected to the cartridge. Alternatively, however, the stator can also simply be inserted into the cartridge or the like. This means that the stator can also be detachably connected to the cartridge.
  • the stopper is mounted in the cartridge so that it can move linearly along the aforementioned longitudinal direction.
  • the stopper follows the medium when dosing the medium.
  • the rotor breakthrough is preferably provided centrally on the plug.
  • the rotor breakthrough can be a stepped bore.
  • the medium can be, for example, an adhesive or sealant, water, an aqueous solution, a paint, a suspension, a viscous raw material, an emulsion or a fat.
  • the medium can also be a gel or alginate.
  • the medium can comprise cells, in particular human, animal or plant cells.
  • the medium can be liquid or pasty.
  • a paste or a pasty product is to be understood as meaning a solid-liquid mixture, in particular a suspension, with a high solids content.
  • the product can contain fillers, for example so-called microballoons, fibrous, in particular short-fibrous, fractions or the like.
  • the cartridge system or the cartridge can include an RFID chip (EnglJ Radio Frequency Identification).
  • an RFID chip EnglJ Radio Frequency Identification
  • a geometry of the stator can be recognized in order to be able to assign the appropriate rotor to the stator, for example. It is thus possible, for example, to identify a size. Furthermore, this also makes batch recognition of the medium received in the cartridge possible.
  • the cartridge system or the cartridge can also have a QR code (English Quick Response), which is lasered into the cartridge, for example. This can be used to identify the medium held in the cartridge, for example. For example, information can then be read, which allows conclusions to be drawn about the contents of the cartridge, namely the medium. For example, a batch recognition, a statement about the service life or the durability of the medium, a product tracking or the like is possible.
  • QR code English Quick Response
  • stator and the cartridge are designed in one piece, in particular in one piece of material, or the stator and the cartridge are connected to one another in a form-fitting, force-fitting and/or cohesive manner.
  • stator and the cartridge form a common component and are not composed of different components.
  • One-piece material means here that the stator and the cartridge are made of the same material throughout. Alternatively, however, the stator and the cartridge can also be two separate components which are connected to one another in a form-fitting, force-fitting and/or cohesive manner.
  • a form-fitting connection is created by the meshing or rear engagement of at least two connection partners, in this case the stator and the cartridge.
  • connection partners for example, snap hooks or the like can be provided on the stator and on the cartridge.
  • a non-positive connection requires a normal force on the surfaces to be connected. Force-locking connections can be realized by frictional locking. The mutual displacement of the surfaces is prevented as long as the counterforce caused by the static friction is not exceeded.
  • the stator is pressed into the cartridge.
  • the connection partners are held together by atomic or molecular forces.
  • Cohesive connections are non-detachable connections that can only be broken by destroying the connection means and/or the connection partner separate.
  • the stator is glued into the cartridge or vulcanized.
  • the stator can be made in one piece.
  • the stator can also be designed in two pieces and has, for example, an inner part made of silicone, which has the snail-shaped opening, and an outer part, which is made of a different plastic material than the inner part.
  • the stator can have an elastomer on the inside and any desired thermoplastic on the outside.
  • the stator can also be made from two different thermoplastics.
  • the rear of the stator, ie facing the plug, can have a cone-shaped geometry. However, this is not mandatory.
  • the rotor opening is closed with the aid of a diaphragm facing the stator.
  • the membrane can be pierced with the help of the rotor unit as soon as the cartridge system is mounted on the drive device.
  • the rotor can have a tip, with the help of which the membrane is pierced.
  • the membrane can also be pierced with the help of the rotor unit before the cartridge system is mounted on the drive device. In this case, the rotor unit is only connected to the drive device after the rotor unit has been inserted into the rotor opening.
  • the membrane comprises a perforation, the perforation preferably dividing the membrane into a plurality of membrane sections.
  • the number of membrane sections is fundamentally arbitrary. For example, two, three or four membrane sections are provided. With the help of the perforation This can prevent parts of the membrane from tearing off and contaminating the medium when the membrane is pierced with the help of the rotor. The perforation ensures that the membrane tears open evenly.
  • the perforation can be cross-shaped, for example, and have two perforation sections crossing one another.
  • the stopper comprises a pressure ring through which the rotor opening is passed and on which the membrane is provided.
  • the pressure ring preferably has the geometry of a half O ring.
  • the membrane is in one piece, in particular in one piece of material, connected to the pressure ring.
  • the pressure ring runs completely around the rotor unit and constricts it. This provides a reliable sealing of the plug with respect to the rotor unit on the medium side.
  • the pressure ring also acts as a tear stop if the membrane is pierced with the help of the rotor unit.
  • the plug comprises a stiffening ring, facing away from the pressure ring, through which the rotor opening is guided.
  • the stiffening ring preferably has a rectangular geometry in cross section.
  • a rounding is provided at a transition from the stiffening ring into the rotor opening. The rounding makes it easier to insert the rotor unit into the rotor opening.
  • At least one circumferential annular groove is provided on the rotor opening.
  • the number of annular grooves is basically arbitrary. For example, two or three annular grooves are provided.
  • the annular grooves together form a labyrinth seal which provides a reliable seal of the plug against the rotating rotor assembly.
  • the annular grooves also serve as a receiving area for displaced material of the plug when the rotor unit performs an eccentric movement in the rotor opening. That is, the plug follows the movement of the rotor unit. This is achieved by selecting the appropriate material for the stopper.
  • the plug has a circumferential first sealing lip facing away from the stator, which rests on the inside of the cartridge, and/or the plug has a circumferential second sealing lip facing the stator, which also rests on the inside of the cartridge.
  • the first sealing lip is preferably acted upon by compressed air and is thus pressed against the cartridge on the inside.
  • the second sealing lip ensures, on the one hand, that the plug is sealed radially in relation to the cartridge and, on the other hand, that the medium is wiped off on the inside of the cartridge.
  • the second sealing lip has greater rigidity than the first sealing lip.
  • the “stiffness” is to be understood as meaning the resistance of the respective sealing lip to deformation.
  • the rigidity can be influenced, for example, by a suitable geometry or a suitable choice of material.
  • the second sealing lip has thicker walls than the first sealing lip. This results in a higher rigidity of the second sealing lip.
  • the first sealing lip extends further out of the plug at the end face than the second sealing lip. That is, the first sealing lip is higher than the second sealing lip.
  • the first sealing lip preferably has thinner walls than the second sealing lip.
  • the cartridge system also includes the rotor unit, which is guided through the rotor opening.
  • the rotor unit can be an integral part of the cartridge system.
  • the rotor unit is detachably connected to the drive device.
  • the connection between the rotor unit and the drive device is preferably also released at the same time.
  • the rotor unit is permanently connected to the cartridge and/or the plug.
  • the rotor unit can also be detachably connected to the cartridge and the plug. In the latter case, the rotor unit can be used several times.
  • a cover closing the cartridge at the back can be provided, for example, which has an opening through which the rotor unit is passed.
  • the rotor unit can have latching hooks or snap hooks, which can be pressed through the opening. As soon as the snap hooks are passed through the opening, the rotor unit is firmly connected to the cartridge and can no longer be separated from it.
  • the rotor assembly is completely encapsulated by the cartridge.
  • the rotor unit cannot be separated from the cartridge and, on the other hand, that direct contact between the rotor unit and the drive device is not possible and not necessary.
  • the rotor unit can be driven by the drive device, for example with the aid of a magnetic coupling.
  • the encapsulation can take place by sealing the cartridge in a fluid-tight manner at the rear. A cover can be provided for this purpose.
  • the rotor unit includes an interface for coupling the rotor unit to a counter-interface of the drive device of the eccentric screw pump.
  • the interface and the counter-interface serve to transmit torque from the drive device to the rotor unit.
  • the interface can have, for example, two wrench flats arranged parallel to one another. In this case, the opposite interface has two key faces that correspond to it.
  • the cross-section of the rotor unit can be rectangular, star-shaped, triangular or square, or round.
  • the interface and the counter-interface may include magnets to implement the aforementioned magnetic coupling.
  • the interface comprises a latching lug which latches into the counter-interface when the rotor unit is connected to the drive device.
  • the detent With the help of the detent, a form-fitting connection of the rotor unit to the mating interface is thus achieved.
  • the counter interface is provided on the drive shaft of the drive device.
  • the detent is designed such that this is sheared off or broken off when the rotor unit is separated from the drive device. This means that the rotor unit can no longer be connected to the drive device.
  • the detent can also deform elastically. In this case, the rotor unit can be used repeatedly.
  • the interface comprises a plurality of elastically deformable arm sections on which the detent is provided.
  • two or four arm sections are provided.
  • the number of arm sections is basically arbitrary. Slots are provided between the arm cuts. This results in a slit-shaped or cross-slit-shaped geometry.
  • the interface can also have a polygonal, rectangular, triangular or star-shaped geometry.
  • the cartridge system also includes the medium accommodated in the cartridge.
  • the medium can be, for example, an alginate, bone wax or any other biological or medicinal material.
  • the medium can contain human, animal or plant cells.
  • the medium can furthermore also comprise bacteria or viruses.
  • a suitable medium can be selected depending on the use of the cartridge system in biomedicine, pharmaceutical technology or industry.
  • the medium can also be a cyanoacrylate, for example.
  • the stopper comprises an indicator which changes its state after the cartridge system has been used.
  • the indicator changes its status after a single use of the cartridge system.
  • the indicator can be a dye, for example be.
  • the change in state can be a color change.
  • the condition may change with exposure to light and/or moisture.
  • the indicator can thus be used to show that the cartridge system has already been used once.
  • the indicator can only change its state after a predetermined time.
  • the indicator can also be designed in such a way that it only changes its status after a predetermined number of uses of the cartridge system.
  • the stopper is made of an air-permeable or air-impermeable material.
  • the plug In the event that the plug is made of an air-permeable material, degassing of the medium is possible under the pressure of the plug on the medium. This is particularly important when processing liquid silicones or acrylates. Thus, bubbles formed in the medium can pass through the air-permeable material.
  • the stopper consists of a porous, open-pored, gas-permeable material.
  • PTFE polytetrafluoroethylene
  • PE polyethylene
  • the porosity of the material is selected, for example, in the range from 1 ⁇ m to 50 nm, preferably in the range from 10 ⁇ m to 50 nm, more preferably in the range from 20 ⁇ m to 50 nm.
  • the stopper may also have a built-in air-permeable membrane.
  • an eccentric screw pump in particular a 3D print head, with a drive device and such an exchangeable cartridge system is proposed, which is detachably connected to the drive device.
  • a bayonet catch for example, can be provided for the detachable connection of the cartridge system to the drive device.
  • the medium is pressurized via the stopper with the help of compressed air or a spring element.
  • an eccentric insert can also be provided in the stopper. The pitch of this insert is adapted to the volumetric quantity and therefore also to the stopper speed. A spindle drive is thus realized. The stopper is then positively controlled and thus follows the medium.
  • the progressing cavity pump e can be mains operated. However, the eccentric screw pump can also be battery operated. As a result, the progressing cavity pump is independent of a power grid.
  • the progressing cavity pump can thus work independently as a handheld device.
  • the progressing cavity pump can be used to dose soldering paste at a manual workstation.
  • the eccentric screw pump can thus be used in the manner of a pipetting device or pipetting aid, with the difference that the eccentric screw pump can also be used to meter highly viscous media.
  • such a self-sufficient eccentric screw pump can also be used to treat quick wounds, for example to treat emergency personnel in the field, or in the operating room. In this case, for example, waxes, in particular bone waxes, adhesives, denture materials, artificial skin or the like can be dosed.
  • FIG. 1 shows a schematic perspective view of an embodiment of an eccentric screw pump
  • FIG. 2 shows a schematic sectional view of the progressing cavity pump according to FIG. 1;
  • FIG. 3 shows a further schematic perspective view of the progressing cavity pump according to FIG. 1;
  • FIG. 4 shows a further schematic perspective view of the progressing cavity pump according to FIG. 1;
  • FIG. 5 shows a further schematic perspective view of the progressing cavity pump according to FIG. 1
  • FIG. 6 shows a schematic perspective view of an embodiment of a bearing housing for the eccentric screw pump according to FIG. 1;
  • FIG. 7 shows the detailed view A according to FIG. 2;
  • FIG. 8 shows a further schematic perspective view of the progressing cavity pump according to FIG. 1;
  • FIG. 9 shows a further schematic perspective view of the progressing cavity pump according to FIG. 1;
  • FIG. 10 shows a schematic perspective view of an embodiment of an interface of a rotor unit for the progressing cavity pump according to FIG. 1;
  • Fig. 11 is a schematic perspective view of another embodiment of a rotor assembly interface for the progressive cavity pump of Fig. 1;
  • FIG. 12 shows the detailed view B according to FIG. 2;
  • FIG. 13 shows a schematic partial sectional view of an embodiment of a cartridge system for the eccentric screw pump according to FIG. 1;
  • FIG. 14 shows a schematic view of an embodiment of a plug for the cartridge system according to FIG. 13;
  • Fig. 15 shows a schematic sectional view of the stopper according to Fig. 14
  • Fig. 16 shows a schematic bottom view of the stopper according to Fig. 14;
  • FIG. 17 shows a schematic view of a further embodiment of a plug for the cartridge system according to FIG. 13;
  • Fig. 18 shows a schematic sectional view of the stopper according to Fig. 17;
  • FIG. 19 shows a schematic view of a further embodiment of a plug for the cartridge system according to FIG. 13;
  • Fig. 20 shows a schematic sectional view of the stopper according to Fig. 19;
  • FIG. 21 shows a schematic view of another embodiment of a plug for the cartridge system according to FIG. 13;
  • Fig. 22 shows a schematic sectional view of the stopper according to Fig. 21;
  • FIG. 23 shows a schematic perspective view of an embodiment of a filling concept for filling the cartridge system according to FIG. 13;
  • FIG. 24 shows a schematic sectional view of a further embodiment of an eccentric screw pump
  • FIG. 25 shows the detailed view C according to FIG. 24
  • FIG. 26 shows a schematic partial sectional view of a further embodiment of a cartridge system for the eccentric screw pump according to FIG. 1 or FIG. 24;
  • FIG. 27 shows the detailed view D according to FIG. 26;
  • FIG. 28 shows a schematic partial sectional view of a further embodiment of a cartridge system for the eccentric screw pump according to FIG. 1 or FIG. 24.
  • FIG. 1 shows a schematic perspective view of an embodiment of an eccentric screw pump 1 for metering a liquid or pasty medium.
  • 2 shows a schematic sectional view of the eccentric screw pump 1.
  • FIG. 3 shows a further schematic perspective view of the eccentric screw pump 1.
  • FIG. 4 shows a further schematic perspective view of the eccentric screw pump 1.
  • FIG. 5 shows a further schematic perspective view the eccentric screw pump 1. Reference is made to FIGS. 1 to 5 at the same time.
  • the eccentric screw pump e 1 includes a drive device 2.
  • the drive device 2 has a drive unit 3, which can include an electric motor.
  • the drive unit 3 is accommodated in a housing 4 .
  • the housing 4 can be tubular.
  • a bearing housing 5 is attached to the front of the housing 4 .
  • the bearing housing 5 can be screwed to the housing 4 with the aid of a connecting element 6, for example.
  • the drive unit 3 drives a drive shaft 7 of the drive device 2 .
  • the drive shaft 7 in turn drives a rotor unit 8 .
  • the rotor unit 8 comprises a flexible shaft or flex shaft 9, which is coupled to the drive shaft 7 by means of an interface, and a helical rotor 10, which is attached to the front of the flexible shaft 9. The rotor 10 is thus driven by the flex shaft 9.
  • the flex shaft 9 is elastically deformable and enables an eccentric movement of the rotor 10.
  • the flex shaft 9 is used to transmit torque from the drive unit 3 to the rotor 10.
  • the flex shaft 9 can be a wire cable which is coated or encased with a plastic material, for example.
  • a universal joint or cardan joint can also be provided, which also enables an eccentric movement of the rotor 10.
  • the flex shaft 9 can also be a flexible rod, in particular a plastic flexible rod, or be designated as such.
  • the flex shaft 9 can be made of a polyetheretherketone (PEEK), polyethylene (PE) or the like, for example.
  • the flexible shaft 9 can have a diameter of 3 mm, for example.
  • the rotor 10 has a tip 11 at the front.
  • the rotor 10 and the flexible shaft 9 can, for example, be designed in one piece, in particular in one piece of material. "In one piece” or “in one piece” means that the flex shaft 9 and the rotor 10 form a common component and are not composed of different components. In the present case, “in one piece” means that the flex shaft 9 and the rotor 10 are made of the same material throughout.
  • the rotor unit 8 is preferably a plastic component.
  • the rotor unit 8 can be a one-piece plastic injection molded component.
  • the flexible shaft 9 and the rotor 10 can also be two separate components that are plugged into one another, for example, and are thus either detachably or non-detachably connected to one another.
  • the flexible shaft 9 can be made of a metallic material and the rotor 10 can be made of a plastic.
  • the flex shaft 9 can be coated with an elastomer.
  • the rotor 10 can be made of a metallic material.
  • the rotor 10 can be made of stainless steel, for example.
  • the rotor 10 can also be designed as a plastic component or ceramic component and can have a wide variety of coatings.
  • the eccentric screw pump 1 also includes a preferably at least partially elastically deformable stator 12.
  • the stator 12 is an elastically deformable elastomeric part with a central opening 13.
  • the opening 13 preferably includes a helical or snail-shaped inner contour.
  • the rotatable rotor 10 is accommodated in the stator 12 and comprises a helical or snail-shaped outer contour corresponding to the stator 12 .
  • An air supply line 14 is provided on the bearing housing 5 and is in fluid communication with an air duct 15 provided in the bearing housing 5 and leading out of the end face of the bearing housing 5 .
  • the medium is conveyed away from the drive shaft 7 according to the endless piston principle through the interaction with the opening 13 of the stator 12 in a longitudinal direction L, which is oriented from the drive device 2 in the direction of the rotor 10 .
  • the delivery volume per unit of time is dependent on the speed, size, pitch and geometry of the rotor 10.
  • Eccentric screw pumps 1 are particularly suitable for conveying a large number of media, in particular viscous, highly viscous and abrasive media.
  • the progressing cavity pump e 1 belongs to the group of rotating displacement pumps.
  • the main parts of the eccentric screw pump e 1 are the drive device 2, the rotatable rotor 10 and the stationary stator 12, in which the rotor 10 moves in rotation.
  • the rotor 10 is designed as a type of round thread screw with an extremely large pitch, large thread depth and small core diameter.
  • the at least partially elastically deformable stator 12 preferably has one more thread turn than the rotor 10 and twice the pitch length of the rotor 10.
  • the medium to be metered always tries to equalize the pressure from high to low pressure. Since the seal between the rotor 10 and the stator 12 is not static, medium will always flow from the pressure side to the suction side. These "slip losses" can be seen on the basis of a characteristic curve as the difference between the theoretical and the actual flow rate.
  • the shape of the pumping chambers is constant so that the medium is not compressed.
  • such an eccentric screw pump 1 can be used to convey not only fluids but also solids.
  • the shearing forces that act on the material to be conveyed are very small, so that plant, animal and human cells, for example, can also be conveyed without being destroyed.
  • a particular advantage of such an eccentric screw pump 1 is that the eccentric screw pump 1 delivers continuously and with little pulsation. This makes them suitable for use in potting plants. Even highly viscous and abrasive media can be pumped without any problems.
  • the progressing cavity pump 1 a wide variety of media can be conveyed gently and with low pulsation.
  • the spectrum of media ranges from water to media that no longer flow by themselves. Since the flow rate is proportional to the speed of the rotor 10, the eccentric screw pump 1 can be used very well for dosing tasks in connection with appropriate measurement and control technology.
  • the progressing cavity pump e 1 combines many of the positive properties of other pump systems. Like the centrifugal pump, the progressing cavity pump 1 has no suction and pressure valves. Like the piston pump, the eccentric worm pump 1 has an excellent self-priming capacity. Like the membrane or peristaltic pump, the progressing cavity pump e 1 can convey any type of inhomogeneous and abrasive media, including those containing solids and fibrous materials.
  • Multi-phase mixtures are also conveyed safely and gently by the eccentric screw pump 1.
  • the eccentric worm pump e 1 is able to handle the highest viscosities of the medium.
  • the progressing cavity pump e 1 has a speed-dependent, continuous flow rate and is therefore able to perform high-precision dosing tasks.
  • the progressing cavity pump e 1 can basically be used in all industrial sectors in which special pumping tasks have to be solved. Examples are environmental technology, especially pumping in the area of sewage treatment plants, the food industry, especially for high-viscosity media such as syrup, quark, yoghurt and ketchup, in the various low-germ processing stages, and the chemical industry, especially for safe pumping and dosing of aggressive, high-viscosity media and abrasive products. With the eccentric screw pump 1, the exact dosing of different media is possible. A repeat accuracy of up to ⁇ 1% can be achieved. Various embodiments of the eccentric screw pump 1 also enable two-component media to be discharged. Because of its design, namely that the rotor 10 moves in the medium and the interior volume of the suction side must be filled, such an eccentric screw pump 1 always has a certain dead space.
  • the rotor unit 8 includes the flex shaft 9 which is elastically deformable. This allows the rotor 10 to move eccentrically in the stator 12. It is also possible to implement this eccentric movement with the aid of joints, in particular universal joints or cardan joints.
  • the stator 12 is subjected to a continuous load during operation, which is why it is subject to wear. This wear is compensated for by regularly replacing the stator 12, with the replacement intervals being determined by the media used and the process parameters.
  • eccentric screw pump 1 With an eccentric screw pump 1 of this type, the medium to be conveyed has hitherto always been supplied from outside the eccentric screw pump 1 .
  • Cartridges, hoses or the like can be provided for this purpose.
  • the drive shaft 7 is sealed at an interface thereof with the drive unit 3 and must at least withstand the feed pressure or the pressure which is generated by the drive device 2 running backwards.
  • the eccentric worm pump e 1 is cleaned by flushing it out with cleaning liquid and by disassembling and cleaning it manually. In many cases, heating or cooling of the eccentric screw pump 1 is possible.
  • the eccentric screw pump e 1 includes a cartridge system 16 which is detachably connected to the drive device 2 .
  • the cartridge system 16 comprises a cartridge 17 which is designed as a plastic component, in particular as a plastic injection molded component.
  • the cartridge 17 is in the form of a disposable syringe, for example.
  • the cartridge 17 has a Luer lock connector 18 on the front.
  • the rotor unit 8 can be part of the cartridge system 16 .
  • the cartridge 17 encloses a cylindrical interior 19 in which the medium to be explained later is accommodated.
  • the interior 19 is a cartridge interior or can be referred to as such.
  • the air duct 15 also opens into the interior space 19 . This means that the air supply 14 is in fluid connection with the interior space 19 via the air duct 15 provided in the bearing housing 5 and leading out of the end face of the bearing housing 5 .
  • Stator 12 is accommodated in interior space 19 .
  • Stator 12 can be formed in one piece, in particular in one piece of material, with cartridge 17 .
  • the cartridge 17 and the stator 12 form a one-piece, in particular a one-piece plastic injection molded component.
  • the stator 12 can also be made of a different material from the cartridge 17 .
  • the stator 12 is made of liquid silicone or LSR (EnglJ Liquid Silicone Rubber, LSR), any elastomer, an engineering plastic, or the like.
  • the stator 12 can be molded onto the cartridge 17 in a plastic injection molding process.
  • a two-component plastic injection molding process can be used for this purpose, for example.
  • the stator 12 can, for example, also simply be pressed into the cartridge 17 and thus be connected to it in a non-positive and/or positive manner.
  • a form-fitting one Connection is created by at least two connection partners engaging in one another or behind, in this case the stator 12 and the cartridge 17.
  • snap-in hooks or snap-in hooks can be provided on the stator 12 and/or the cartridge 17.
  • a non-positive connection requires a normal force on the surfaces to be connected. Force-locking connections can be realized by frictional locking. The mutual displacement of the surfaces is prevented as long as the counterforce caused by the static friction is not exceeded.
  • the stator 12 is preferably pressed into the cartridge 17 .
  • the stator 12 can also be connected to the cartridge 17 with a material connection. This can be done, for example, by the previously mentioned two-component plastic injection molding process. In the case of material connections, the connection partners are held together by atomic or molecular forces. Cohesive connections are non-detachable connections that can only be separated by destroying the connection means and/or the connection partner. For example, the stator 12 can be glued into the cartridge 17 .
  • the stator 12 is provided on the front side of the cartridge 17 . Facing away from the Luer lock connection 18, the cartridge 17 comprises two arm sections 20, 21, which can be brought into positive engagement with the bearing housing 5 in order to connect the cartridge system 16 to the drive device 2.
  • the cartridge 17 also includes a cone-shaped section 22 (FIG. 7) facing away from the Luer lock connector 18 .
  • the bearing housing 5 comprises a conical counter-engagement portion 23 which is suitable for engaging in the section 22 from a handle.
  • Conical counter-section 23 includes a central opening 24 through which the drive shaft 7 is passed.
  • annular groove 25 runs around the counter-engagement section 23, in which an O-ring 26 (FIG. 7) is accommodated.
  • the bearing housing 5 also includes a bayonet lock 27 which enables the cartridge system 16 to be connected to the drive device 2 quickly and easily.
  • the bayonet catch 27 comprises two slot-shaped recesses 28, 29 provided on the bearing housing 5.
  • the cartridge system 16 is first pushed onto the conical mating engagement section 23, as a result of which the latter engages in the engagement section 22 of the cartridge 17.
  • the cartridge system 16 is then rotated 90° clockwise relative to the drive device 2 .
  • the arm sections 20, 21 come into engagement with the recesses 28, 29 of the bayonet catch 27, as a result of which the engagement section 22 of the cartridge 17 is pushed further onto the counter-engagement section 23 until the O-ring 26 seals against the cartridge 17 and ends 30 ( Fig. 7) of the arm sections 20, 21 on an end face 31 (Fig. 6 and 7) of the bearing housing 5 abut.
  • fluid-tight means in particular both gas-tight and liquid-tight.
  • the interior 19 of the cartridge 17 can now be pressurized via the air duct 15 .
  • the sealing of the cartridge system 16 with the aid of the O-ring 26 on the cone-shaped counter-engagement section 23 makes it easy to mount the cartridge system 16 on the drive device 2 .
  • the cartridge system 16 is rotated in relation to the bearing housing 5, the cartridge system 16 is pulled against the bearing housing 5 due to the bayonet lock 27 and thus seals off the cartridge 17 with the aid of the O-ring 26.
  • the cone-shaped counter-engagement section 23 also enables the cartridge system 16 to be centered on the bearing housing 5.
  • the counter-engagement section 23 thus fixes the cartridge system 16 on the drive device 2.
  • the use of the bayonet lock 27 reliably prevents the cartridge system 16 from becoming detached from the drive device 2 unintentionally. Sealing takes place via the cone-shaped handle section 22 and the cone-shaped counter-engagement section 23 and the O-ring 26.
  • the bayonet catch 27 can be used to exert uniform pressure on the cartridge 17, so that the end faces 30, 31 are pressed against one another.
  • the geometry of the counter-engagement section 23 is adapted to the section 22 of the cartridge 17 that is engaged.
  • FIG. 8 shows a further schematic perspective view of the eccentric screw pump 1, the cartridge 17 not being shown.
  • an interface 32 (FIGS. 10 and 11) is provided between the rotor unit 8, in particular the flex shaft 9, and the drive shaft 7.
  • the interface 32 comprises two key faces 33 arranged opposite one another and a plurality of elastically deformable arm sections 34, 35. As shown in FIG. 10, two such arm sections 34, 35 can be provided.
  • the drive shaft 7 comprises a counter-interface 41 corresponding to the interface 32.
  • the counter-interface 41 comprises key surfaces 42, 43 corresponding to the key surfaces 33.
  • the key surfaces 33 and the key surfaces 42, 43 serve to transmit torque from the drive shaft 7 on the flex shaft 9.
  • the mating interface 41 also includes a shoulder 44, which is designed as a circumferential annular groove. The detent 40 engages in the paragraph 44 in a form-fitting manner.
  • the interface 32 of the rotor unit 8 is pushed into the interface 41 of the drive shaft 7, as shown in FIGS.
  • the arm sections 34 to 37 of the interface 32 deform in a spring-elastic manner until the detent 40 engages in the shoulder 44 of the counter-interface 41 in a form-fitting manner.
  • the rotor unit 8 is pulled out of the drive shaft 7 so that the interface 32 and the counter-interface 41 separate from one another.
  • the detent 40 can be sheared off the interface 32 or break off. As a result, it is no longer possible to reconnect the rotor unit 8 to the drive device 2 .
  • the arm sections 34 to 37 deform elastically when the rotor unit 8 is pulled out of the drive shaft 7, so that the locking lug 40 no longer engages positively with the shoulder 44 of the counter interface 41.
  • the rotor unit 8 can now be pulled off the drive device 2 . Due to the fact that the detent 40 does not shear off in this case, the rotor unit 8 can also be used several times.
  • the cartridge system 16 comprises a plug 45 accommodated in the cartridge 17.
  • the plug 45 is mounted in the cartridge 17 in a linearly displaceable manner along the longitudinal direction L. That is, the plug 45 can move along the longitudinal direction L and counter to the longitudinal direction L in the cartridge 17 .
  • the rotor unit 8, in particular the rotor 10, is guided through the plug 45.
  • a rotor opening 46 that breaks through the plug 45 is provided.
  • the cartridge system 16 with the cartridge 17, the stator 12 and the plug 45 preferably forms a disposable or a disposable item.
  • the cartridge system 16 can also include the rotor unit 8 , in particular the rotor 10 . However, this is not mandatory. Alternatively, the cartridge system 16 can also be used several times. In the latter case, the cartridge system 16 can be refilled.
  • Disposable process solutions also known as single-use technologies, are used in particular to manufacture biopharmaceutical products. This means complete solutions from one-way systems, which are also referred to as single-use systems, for an entire process line. This may include, for example, media and buffer preparation, bioreactors, cell harvest, depth filtration, tangential flow filtration, chromatography, and virus inactivation.
  • biotechnical processes include nutrient solutions, cells, buffers for stabilizing the pH value, as well as acids and bases for adjusting and regulating the pH value during cultivation. All media used must be sterilized before use.
  • two main processes are used in biotechnology: heat sterilization at at least 121 °C at 1 bar overpressure for at least 20 minutes and sterile filtration.
  • heat sterilization at at least 121 °C at 1 bar overpressure for at least 20 minutes
  • sterile filtration is the method of choice.
  • the disposable process solutions available are each to be regarded as a self-contained module.
  • the preconfigured disposable systems which consist of hoses, disposable tanks, pump chambers and filtration or chromatography modules, are self-contained. Sterile connection technologies, usually hose connections, are therefore required to connect two consecutive process steps.
  • thermoplastic hoses can be welded together in a sterile manner or existing connections can be severed and the hose ends can be welded.
  • hybrid processes in which single-use systems are combined with conventional stainless steel and glass systems.
  • closed systems in which the one-way systems are linked together in the order of the process steps, and station systems, in which the intermediate products are transported to the next process step using mobile containers.
  • single use (often also referred to as “disposable”) defines an item that is intended for single use.
  • this consists of a plastic material such as polyamide (PA), polycarbonate (PC), polyethylene (PE), polyethersulfone (PESU), polyoxymethylene (POM), polypropylene (PP), polytetrafluoroethylene (PTFE), polyvinyl chloride ( PVC), cellulose acetate (CA) or ethylene vinyl acetate (EVA), and is discarded after use.
  • PA polyamide
  • PC polycarbonate
  • PE polyethylene
  • PESU polyethersulfone
  • POM polyoxymethylene
  • PP polypropylene
  • PTFE polytetrafluoroethylene
  • PVC polyvinyl chloride
  • CA cellulose acetate
  • EVA ethylene vinyl acetate
  • the plug 45 includes the rotor opening 46 through which the rotor unit 8, in particular the rotor 10, is passed.
  • the rotor unit 8 in particular the rotor 10
  • the stator 12 comprises an inner part 47, in particular an elastomer part, on which the opening 13 with the helical inner geometry is provided, and an outer part 48, which accommodates the inner part 47.
  • the outer part 48 is tubular and takes the inner part 47 in itself.
  • the inner part 47 is elastically deformable.
  • the inner part 47 can be made of a thermoplastic elastomer (TPE) and the outer part 48 can be made of a polyurethane (PU).
  • TPE thermoplastic elastomer
  • PU polyurethane
  • the stator 12 can be a one-piece or a multi-piece component.
  • the inner part 47 can be pressed into the outer part 48 .
  • the inner part 47 and the outer part 48 can also be produced as a one-piece component in a two-component injection molding process.
  • the elastomer part 47 is made of a liquid silicone or LSR.
  • the outer part 48 can be made of any thermoplastic material, such as PE, ABS, PP or the like.
  • the elastomer part 47 can also be made of a thermoplastic material.
  • the stator 12 is inserted, clipped, glued into the cartridge 17 or connected to it in some other way.
  • the stator 12 can, as mentioned above, be designed in one piece, in particular in one piece of material, with the cartridge 17 .
  • the stator 12 can also be removed from the cartridge 17 .
  • the plug 45 can be subjected to an overpressure.
  • a sterile filter or moisture filter can be provided on the air supply 14 . This can be provided both inside the bearing housing 5 and outside, for example in the air supply 14 .
  • plug 45 as shown in Figures 14 and 15, it comprises a cylindrical or barrel-shaped geometry.
  • the stopper 45 is constructed rotationally symmetrically to a central or symmetrical axis 49 .
  • the stopper 45 can be made, for example, from an LSR, a two-component silicone, PE, POM, PP, PTFE or from an elastomer.
  • the stopper 45 can also be made of a porous, open-pored, gas-permeable material such as PTFE or PE. As a result, gas bubbles trapped in the medium can escape via the porous plug 45 .
  • the porosity of the material is, for example, in the range from 1 pm to 50 nm, preferably in the range from 10 ⁇ m to 50 nm, more preferably in the range from 20 ⁇ m to 50 nm.
  • the plug 45 can also include a built-in membrane.
  • the plug 45 Facing away from the stator 12 , the plug 45 includes a first sealing lip 50 that runs completely around the axis of symmetry 49 .
  • the first sealing lip 50 rests against the cartridge 17 on the inside.
  • the plug 45 comprises a second sealing lip 51, which also rests on the inside of the cartridge 17.
  • the second sealing lip 51 is placed on the medium side.
  • the first sealing lip 50 is placed away from the medium.
  • the second sealing lip 51 has a wiping function and is more rigid than the first sealing lip 50. Viewed along the axis of symmetry 49, the more flexible first sealing lip 50 extends further out of the plug 45 than the second sealing lip 51.
  • the rotor opening 46 comprises a plurality of annular grooves 52, 53 running around the axis of symmetry 49, which together form a labyrinth seal 54 in order to seal the flex shaft 9 and/or the rotor 10 against the plug 45 in a fluid-tight manner.
  • a labyrinth seal 54 in order to seal the flex shaft 9 and/or the rotor 10 against the plug 45 in a fluid-tight manner.
  • the plug 45 On the upper side, ie facing away from the medium, the plug 45 comprises a stiffening ring 55 which runs completely around the axis of symmetry 49 and which is broken through by the rotor opening 46 .
  • a rounding 56 is provided in a transition between the stiffening ring 45 and the rotor opening 46 , which makes it easier to insert the rotor unit 8 into the rotor opening 46 .
  • a pressure ring 57 Facing the medium, ie facing away from the stiffening ring 55, a pressure ring 57 is provided.
  • the pressure ring 57 constricts itself around the rotor unit 8 and seals it off.
  • the pressure ring 57 is in the form of a halved O-ring.
  • the rotor opening 46 is closed with the aid of a membrane 58 which is connected to the pressure ring 57 .
  • the membrane 58 can be pierced with the help of the rotor 10, in particular with the help of the tip 11 of the rotor 10. If the membrane 58 is punctured, the pressure ring 57 ensures that the stopper 45 does not tear any further.
  • the membrane 58 comprises a plurality of membrane sections 59 to 62.
  • the number of membrane sections 59 to 62 is arbitrary. For example, two, three or four membrane sections 59 to 62 can be provided.
  • a performance 63 which is cross-shaped is provided between the membrane sections 59 to 62 .
  • the perforation 63 comprises a first perforation section 64 and a second perforation section 65 which are placed perpendicular to each other and form the cross-shaped perforation 63 .
  • the provision of the perforation 63 makes it possible to prevent parts of the membrane 58 from becoming detached when the rotor 10 pierces it.
  • the plug 45 seals both on the first sealing lip 50 and on the second sealing lip 51 with an overlap. This means that the sealing lips 50, 51 are compressed radially in the cartridge 17. At the same time, a wiping function on the side of the medium and on the inside of the cartridge 17 is realized.
  • the stopper 45 or the material used for the stopper 45 can include an indicator which changes its state when the stopper 45 is used or after a certain period of time.
  • the indicator can be a dye, for example. That is, the plug 45 changes color with a single use. For example, plug 45 discolor on contact with air or moisture or the medium. For example, the plug 45 changes color after a certain time, for example eight hours.
  • FIGS. 17 and 18 show a further embodiment of a stopper 45.
  • the stopper 45 according to FIGS. 17 and 18 is particularly suitable for media of low to medium viscosity.
  • the plug 45 comprises two sealing lips 50, 51.
  • the plug 45 according to Figs. 17 and 18 comprises three annular grooves 52, 53, of which in Fig 18 only two are provided with a reference number. Facing the medium, the plug 45 comprises a conical section 66 that bulges out of the plug 45.
  • the stator 12 has a conical geometry that corresponds to the conical section 66 of the plug 45, in particular a counter-conical section 67 , as shown in FIG. 13, for example.
  • FIGS. 19 and 20 show another embodiment of a plug 45.
  • the plug 45 according to FIGS. 19 and 20 comprises only one sealing lip 51 facing the medium Annular grooves 52, 53 are provided.
  • the stopper 45 according to FIGS. 19 and 20 is particularly suitable for low to high viscosity media.
  • the stopper 45 is particularly preferably suitable for highly viscous media.
  • the rotor opening 46 is designed as a stepped bore.
  • FIGS. 21 and 22 show a further embodiment of a stopper 45.
  • the stopper 45 according to FIGS. 21 and 22 is particularly suitable for low to high viscosity materials.
  • the plug 45 according to FIGS. 21 and 22 differs from the plug 45 according to FIGS. 19 and 20 in that the rotor opening 46 is designed such that the plug 45 only in the area of the thin-walled membrane 58 is in contact with the plug 45.
  • the plug 45 comprises only one circumferential sealing lip 51 facing the medium.
  • the plug 45 is preferably made of a particularly elastic material.
  • the progressing cavity pump e 1 can be used in particular for additive or generative manufacturing. That is, the progressive cavity pump 1 is a 3D print head or can be referred to as such. 3D printing is a comprehensive term for all manufacturing processes in which material is applied layer by layer to create three-dimensional objects.
  • the layered structure is computer-controlled from one or more liquid or solid materials according to specified dimensions and shapes.
  • 3D printing Physical or chemical hardening or melting processes take place during construction.
  • Typical materials for 3D printing are plastics, synthetic resins, ceramics and metals.
  • carbon and graphite materials have also been developed for the 3D printing of carbon parts.
  • it is a primary forming process no special tools are required for a specific product that have stored the respective geometry of the workpiece, such as casting molds.
  • 3D printers are used in industry, in model making and research to produce models, samples, prototypes, tools, end products or the like. Furthermore, these are also used for private use. There are also applications in home and entertainment, construction, and art and medicine.
  • 3D printing has the advantage that the time-consuming production of molds and mold changes are no longer necessary.
  • 3D printing has the advantage that there are no additional processing steps after the primary shaping. In most cases, the process is energetically cheaper, especially if the material is only built up once in the required size and mass.
  • post-processing may be necessary depending on the area of application.
  • the eccentric screw pump e 1 can be used for so-called bioprinting.
  • bioprinting The field of application of bioprinting is still very young and represents the latest step in cell culture technology. It can be seen as a special form of additive manufacturing at the interface between medical technology and biotechnology.
  • the topic of "bioprinting” is often introduced with words about the great need for donor organs. It is essential that tissue and organs are artificially produced in the future in order to meet the enormous demand. Realistically, this vision is still a long way off if it should ever become reality.
  • mini-organs are printed, which can depict all the essential functions of a shelf organ. Using microfluidic techniques, these mini-organs can be combined into multi-organ systems and the systemic effects of active substances can thus be tested without the need for animal experiments.
  • cell-loaded gels or matrices are produced for maintaining and cultivating the same with the aid of the eccentric screw pump 1, in particular with the aid of a bioprinter.
  • This is done through a layered structure, which is known from additive manufacturing. Since most of the media used in bioprinting are loaded with living cells, which can only be produced with considerable expenditure of time and money, gentle application is essential. The stress on the deployed cells increases with the cell density and the viscosity of the medium. For meaningful constructs, however, the highest possible cell density and stability are required. This creates a tension between cell concentration and application technology.
  • the special feature of the eccentric screw pump 1 consists in the design of the cartridge system 16 as a disposable item.
  • the cartridge system 16 containing the stator 12 is replaced after it has been used once.
  • the drive device 2 itself remains. It is also necessary to replace the plug 45, which is part of the cartridge system 16. It is also possible to exchange the rotor 10 in the event that this is part of the cartridge system 16 .
  • cartridge system 16 as a single-use printhead has many advantages over established methods.
  • a high level of precision and resolution can be achieved during the application. Process fluctuations are compensated and enable consistent and reproducible printing results. Ambient parameters are leveled. It is a gentle product Delivery of low to high-viscosity media possible. There is no clogging of a dosing needle.
  • the application can be done without pulsation. Active withdrawal of medium into the cartridge system 16 is possible in order to prevent thread formation or dripping.
  • the hygienic implementation or sterilization enables a contamination-free process. This is guaranteed by the one-time use. A low dead volume enables almost complete extrusion of the medium. Easy integration into existing bioprinters is possible. The design does not require a separate controller and is geometrically optimized for bioprinters. It is easy to handle without additional tools.
  • both the interior 19 of the cartridge 17 can be sealed off from the environment and the drive unit 3 can be protected against contamination with the medium. Because the medium is not supplied via a hose or pipeline, but is held directly in the cartridge system 16, the dead volume can be reduced since the medium is very expensive and even the smallest amounts are too valuable to use as dead volume to lose. Loss-free feeding and at least almost complete emptying of the cartridge system 16 are ensured.
  • the cartridge system 16 is a disposable item, it can be easily sterilized. Due to the fact that the cartridge system 16 can be replaced, the drive device 2 itself does not have to be cleaned. It is therefore not necessary to completely dismantle the drive device 2 in order to clean the eccentric screw pump 1 .
  • the cartridge system 16 can be used very easily and quickly be changed, whereby the eccentric screw pump 1 is ready for use again in a very short time.
  • Biological media are usually dosed within a working range of + 4 °C to + 40 °C, since most cells can only survive in a narrow temperature range.
  • the media to be printed are very often subject to a temperature-controlled gelation mechanism that ensures dimensional stability during printing. This requires precise temperature control. Refrigeration is also important so that some cell types do not die and certain gels can be printed.
  • the medium can be sealed off from the interior space 19 with the aid of the eccentrically sealing plug 46 .
  • the plug 45 serves not only for sealing, but also fulfills the function of power transmission to the medium in order to supply a preliminary pressure for the metering of the same. This form can be applied, for example, by compressed air supplied via the air supply 14 or by a spring.
  • FIG. 23 schematically shows a filling concept for filling the cartridge system 16.
  • FIG. The membrane 58 of the plug 45 faces the stator 12 .
  • the plug 45 is pushed into the cartridge 17 until the plug 45 is in contact with the stator 12 .
  • a syringe 68 filled with a medium M is then connected to the Luer lock connection 18 of the cartridge 17 via an adapter 69 .
  • the cartridge system 16 is now filled with the medium M, with the plug 45 moving away from the stator 12 .
  • the cartridge system 16 is connected to the drive device 2 .
  • the membrane 58 is pierced by the rotor 10 .
  • a nozzle 70 is attached to the Luer lock connection 18 .
  • the cartridge system 16 is connected to the drive device 2 with the aid of the bayonet lock 27 .
  • the dosing of the medium M can now be started.
  • the plug 45 To fill the cartridge 17 and to protect the medium M from the environment, it is necessary for the plug 45 to be closed. This is solved in that the stopper 45 is provided with the perforable membrane 58 in the middle. After the cartridge system 16 has been filled, this should still be tight when the rotor 10 pierces the membrane 58 from above. Furthermore, the plug 45 must allow the eccentric movement of the rotor 10 while the cartridge system 16 is being completely emptied and still remain sealed. This is achieved by an appropriate choice of material for the plug 45.
  • the medium M In order to largely eliminate the dead space, it is necessary for the medium M to be able to remain in as few indentations, cavities or undercuts as possible. A product-contacting inner geometry of the cartridge 17 that is as simple as possible is therefore well suited. Therefore, the cartridge 17 is also cylindrical on the inside.
  • the potential disadvantage that the rotor 10 has to be guided through the center of the cartridge 17 and that medium M can potentially stick to the rotor unit 8 is compensated for by the wiping function of the plug 45 .
  • An optimal emptying of residues is achieved by a conically tapering stator 12 and a correspondingly shaped plug 45, as is also shown in FIGS. 13 and 18, for example.
  • the rotor-stator combination can be designed for a small dosing volume up to failure.
  • the stopper 45 can be irreversibly destroyed after a single use, for example by puncturing the membrane 58. It is possible for the rotor 10 to snap into the cartridge 17 so that it cannot be separated from the cartridge system 16. An irreversible closure of the cartridge 17 is possible, so that the damaged stopper 45 cannot be replaced. Furthermore, a color indication is possible, which indicates a single use.
  • the handling of the cartridge system 16 is simplified to such an extent that a user only has to fill the cartridge system 16 , insert the rotor unit 8 into the drive device 2 and tighten the cartridge system 16 on the drive device 2 . Dismantling and assembly are possible without tools.
  • the cartridge system 16 can be sterile filled, operated and exchanged without residues remaining.
  • the rotor 10, in particular the rotor unit 8 is automatically removed from the drive device 2 when the cartridge system 16 is pulled off.
  • the handling is therefore largely the same as that of a regular cartridge.
  • the extrusion is controlled via stepper motor signals from a controller. No separate control is required, which improves handling in practice.
  • a reduction in weight and size is desirable.
  • the greatest savings are possible by selecting a suitable drive unit 3. Since the sealing of the drive unit 3 does not have to withstand high pressures, it can also be made smaller.
  • the materials for the drive device 2 are chosen so that they are as light as possible.
  • the housing 4 can be partially made of metal or plastic. Since the components rotor 10, stator 12, plug 45 and cartridge 17 are made of plastic, the weight is further reduced.
  • the temperature of the medium M can be regulated via an external element that can be plugged onto the cartridge system 16 .
  • the cooling or heating takes place directly on an outer surface of the cartridge 17 and can be kept constant over the entire length of the cartridge 17 by means of an adapted shape.
  • This is implemented on the one hand by the relatively large distance between the drive unit 3 and the cartridge system 16, on the other hand by a suitable choice of material.
  • Plastic prevents the conduction from the drive unit 3 to the medium M.
  • Metal provided on the drive unit 3 promotes heat dissipation to the environment.
  • the use of the progressing cavity pump e 1 does not have to be limited to bioprinting. Materials such as silicones, epoxy resins, polyurethanes, ceramic, metal and solder pastes can also be printed. With a compact design, it is also conceivable to open up the market for amateur 3D printers. Another possible application is the printing of meat substitute products. Strict hygienic regulations also apply here. Many different materials are used and the viscosity can be very high. It is irrelevant whether the substitute products were generated directly from animal sources or are reproduced or replaced by plant sources.
  • cartridge system 16 also makes sense in a laboratory environment in which small quantities are tested and rapid product changes take place. If, for example, different formulations of an adhesive compound are tested, the entire eccentric screw pump would always have to be dismantled and cleaned in the case of an eccentric screw pump without such a cartridge system 16 . Since there are no sterility requirements for adhesives, it would also be conceivable to only change the cartridge 17 and not the rotor unit 8 . Different cartridge sizes ensure usability in different areas.
  • the cartridge system 16 can be used for the precise application of material in wound care, in the body, in operations, in dental treatments or for dispensing medication.
  • One The interface between additive manufacturing and medical technology is, for example, the printing of tablets. Problems with interactions, overdosing and underdosing as well as forgetting to take a tablet can be counteracted by individually creating tablets with patient-specific active ingredients and active ingredient contents.
  • the eccentric worm pump 1 can also be used for printing tablets.
  • Fig. 24 shows a schematic sectional view of a further embodiment of an eccentric screw pump 1.
  • Fig. 25 shows the detailed view C according to Fig. 24.
  • the eccentric screw pump 1 according to Fig. 24 differs from the eccentric screw pump e 1 according to Fig. 1 and 2 only in that the cartridge system 16 has a spring element 71 which is arranged between the plug 45 and the bearing housing 5. Ring-shaped pressure pieces 72, 73 are provided on both sides of the spring element 71. In addition, pressurization via the air supply 14 is also possible.
  • the interior 19 of the cartridge 17 can also be subjected to a negative pressure, in particular a vacuum.
  • this task is taken over by the spring element 71 instead of pressurizing the plug 45 with air.
  • the spring element 71 has a linear characteristic.
  • the exertion of force on the plug 45 can take place on the one hand via air pressure, with the aid of a spring force of the spring element 71 or with the aid of a spindle drive (not shown).
  • an eccentric insert in the plug 45 is provided.
  • the pitch of this eccentric insert is adapted to the volumetric quantity and therefore also to the stopper speed. That is, the plug 45 is positively guided.
  • a slide bushing 74 for supporting the drive shaft 7 in the bearing housing 5 is provided.
  • the slide bushing 74 includes a first sealing ring 75 and a second sealing ring 76. It is also possible for only one sealing ring 75, 76 to be provided.
  • the sealing ring 75 seals against a vacuum in the interior space 19 .
  • FIG. 26 shows a schematic sectional view of a further embodiment of a cartridge system 16.
  • FIG. 27 shows the detailed view D according to FIG .
  • a cover 79 closing the cartridge 47 is provided.
  • the cover 79 can be plate-shaped and includes a central opening 80 through which the rotor unit 8 is passed.
  • the cover 79 includes a circumferential handle from section 81, which engages behind the latching hooks 77, 78. This means that the cover 79 can be pressed into the cartridge 17, as indicated by arrows in FIG. The cover 79 can no longer be separated from the cartridge 17.
  • Latch hooks or snap hooks 82, 83 can be provided on the rotor unit 8, in particular on the flexible shaft 9.
  • the number of snap hooks 82, 83 is arbitrary.
  • the snap hooks 82, 83 can grip the cover 79 behind.
  • the snap hooks 82, 83 protrude radially further out of the rotor unit 8 than the diameter of the opening 80 is large.
  • the rotor unit 8 can be guided through the opening 80 . As soon as the snap hooks 82, 83 have passed through the opening 80, they engage behind the cover 79. Now the rotor unit 8 can no longer be separated from the cartridge system 16 either.
  • the cartridge system 16 and all components of the cartridge system 16 can actually only be used once.
  • the rotor unit 8 and the plug 45 could also be cleaned and repeatedly be reused.
  • the cover 79 can at least ensure that the cartridge 17 is only used once. The advantage here can be seen in single use or contamination, for example in the case of toxic or carcinogenic active substances, as well as in cleaning and self-protection.
  • FIG. 28 shows a schematic sectional view of a further embodiment of a cartridge system 16.
  • the cartridge system 16 according to FIG. 28 is completely encapsulated.
  • a cover 84 is provided on the back of the cartridge 17 for this purpose.
  • the cover 84 is glued or fused to the cartridge 17, for example.
  • the cover 84 is connected to the cartridge 17 in a fluid-tight manner.
  • the cartridge system 16 is thus completely encapsulated and, in addition to the cartridge 17, includes the stator 12, the rotor unit 8 and the plug 45 (not shown).
  • the interface 32 of the rotor unit 8, in particular the flex shaft 9, is designed as a non-contact interface.
  • the interface 32 is provided on the flexible shaft 9 . Accordingly, a corresponding counterpart interface is provided on the drive device 2 .
  • the interface 32 can be a magnetic coupling or part of a magnetic coupling, for example.
  • all embodiments of the cartridge system 16 or the cartridge 17 can have an RFID (Radio Frequency Identification) chip.
  • RFID Radio Frequency Identification
  • a geometry of the stator 12 can be recognized in order, for example, to be able to assign the appropriate rotor 10 to the stator 12 . It is thus possible, for example, to identify a size.
  • batch recognition of the medium M contained in the cartridge 17 is also possible.
  • the cartridge system 16 or the cartridge 17 can also have a QR code (English Quick Response), which is lasered into the cartridge 17, for example. With this, for example, the medium M accommodated in the cartridge 17 can be identified. Information can then be read out, for example, which allows conclusions to be drawn about the contents of the cartridge 17, namely the medium M. For example, a batch recognition, a statement about the service life or the durability of the medium M, a product tracking or the like is possible.
  • the eccentric screw pump 1 can be mains operated or battery operated. This means that battery operation of the drive unit 3 is possible. As a result, the eccentric screw pump e 1 is independent of a power grid.
  • the eccentric screw pump 1 can thus work independently as a handheld device.
  • the eccentric screw pump 1 can be used to meter soldering paste at a manual workstation.
  • the eccentric screw pump 1 can thus be used in the manner of a pipetting device or pipetting aid, with the difference that the eccentric screw pump 1 can also be used to dose highly viscous media M.
  • a self-sufficient eccentric screw pump 1 can also be used to treat quick wounds, for example for field treatment by emergency services, in doctors' surgeries or in the operating room.
  • waxes in particular bone waxes, adhesives, medicines, denture materials, artificial skin or the like can be dosed.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Rotary Pumps (AREA)

Abstract

L'invention concerne un système de cartouche (16) pour une pompe à vis excentrique (1), ledit système de cartouche comprenant : une cartouche (17) destinée à contenir une substance (M) à doser ; un stator (12) qui est disposé sur la cartouche (17) et qui coopère avec un ensemble rotor (8) de la pompe à vis excentrique (1) afin de doser la substance (M) ; et un bouchon (45) qui est monté mobile dans la cartouche (17) pour assurer l'étanchéité fluidique de la cartouche (17), le bouchon (45) présentant une ouverture de rotor (46) à travers laquelle passe l'ensemble rotor (8).
PCT/EP2021/072334 2020-10-21 2021-08-11 Système de cartouche et pompe à vis excentrique WO2022083913A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US18/033,026 US20230392594A1 (en) 2020-10-21 2021-08-11 Cartridge system and eccentric screw pump
DE112021005611.5T DE112021005611A5 (de) 2020-10-21 2021-08-11 Kartuschensystem und Exzenterschneckenpumpe
CN202180071792.XA CN116529486A (zh) 2020-10-21 2021-08-11 筒系统和单螺杆泵

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20203116.7A EP3988790A1 (fr) 2020-10-21 2020-10-21 Système de cartouche et pompe à vis sans fin excentrique
EP20203116.7 2020-10-21

Publications (1)

Publication Number Publication Date
WO2022083913A1 true WO2022083913A1 (fr) 2022-04-28

Family

ID=73005446

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2021/072334 WO2022083913A1 (fr) 2020-10-21 2021-08-11 Système de cartouche et pompe à vis excentrique

Country Status (5)

Country Link
US (1) US20230392594A1 (fr)
EP (1) EP3988790A1 (fr)
CN (1) CN116529486A (fr)
DE (1) DE112021005611A5 (fr)
WO (1) WO2022083913A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022127309A1 (de) 2022-10-18 2024-04-18 Visec (Asia) Technology Pte Ltd. Verfahren und Spritzgussform zur Herstellung einer Rotoreinheit für eine Exzenterschneckenpumpe sowie eine Rotoreinheit, eine Statoreinheit und eine Exzenterschneckenpumpe

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2944819A1 (fr) * 2014-05-12 2015-11-18 Hugo Vogelsang Maschinenbau GmbH Pompe à vis sans fin excentrique
EP3165288A1 (fr) * 2015-11-06 2017-05-10 ViscoTec Pumpen- und Dosiertechnik GmbH Dispositif de vaporisation
DE102018009512B3 (de) * 2018-12-06 2019-11-21 Hans-Peter Moser Dosiervorrichtung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2944819A1 (fr) * 2014-05-12 2015-11-18 Hugo Vogelsang Maschinenbau GmbH Pompe à vis sans fin excentrique
EP3165288A1 (fr) * 2015-11-06 2017-05-10 ViscoTec Pumpen- und Dosiertechnik GmbH Dispositif de vaporisation
DE102018009512B3 (de) * 2018-12-06 2019-11-21 Hans-Peter Moser Dosiervorrichtung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022127309A1 (de) 2022-10-18 2024-04-18 Visec (Asia) Technology Pte Ltd. Verfahren und Spritzgussform zur Herstellung einer Rotoreinheit für eine Exzenterschneckenpumpe sowie eine Rotoreinheit, eine Statoreinheit und eine Exzenterschneckenpumpe

Also Published As

Publication number Publication date
EP3988790A1 (fr) 2022-04-27
US20230392594A1 (en) 2023-12-07
DE112021005611A5 (de) 2023-08-24
CN116529486A (zh) 2023-08-01

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