WO2021187516A1 - Promoteur de croissance animale et aliment pour bétail - Google Patents

Promoteur de croissance animale et aliment pour bétail Download PDF

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Publication number
WO2021187516A1
WO2021187516A1 PCT/JP2021/010781 JP2021010781W WO2021187516A1 WO 2021187516 A1 WO2021187516 A1 WO 2021187516A1 JP 2021010781 W JP2021010781 W JP 2021010781W WO 2021187516 A1 WO2021187516 A1 WO 2021187516A1
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WO
WIPO (PCT)
Prior art keywords
livestock
family
extract
tree
feed
Prior art date
Application number
PCT/JP2021/010781
Other languages
English (en)
Japanese (ja)
Inventor
俊佑 李
洋一郎 川村
Original Assignee
国立大学法人 東京大学
川村通商株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 国立大学法人 東京大学, 川村通商株式会社 filed Critical 国立大学法人 東京大学
Publication of WO2021187516A1 publication Critical patent/WO2021187516A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/22—Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Definitions

  • the present invention relates to an animal growth promoter, livestock feed containing the same, and a method for raising livestock.
  • Antibiotics are medicines originally developed for the treatment of biological diseases, but about 70 years ago, by adding some antibiotics to livestock feed, the health of livestock can be maintained. Not only that, it was discovered that the utilization efficiency of nutritional components was greatly increased. Since then, it has played a major role as an additive for all livestock feeds around the world (for example, Patent Document 1), and is now indispensable in the livestock industry, especially in developing countries where the feed environment is not favorable. It has become. Further, it is known that artificially bred early weaning pigs can be protected from intestinal pathogens and also have a growth promoting effect by feeding a feed containing an antibiotic.
  • the present invention targets animal growth promoters.
  • Animal growth promoter containing an extract of Rhus family tree ⁇ 2> The animal growth promoter according to ⁇ 1> above, wherein the extract contains tannin derived from a tree of the family Rhus family in the range of 50 to 100% by weight;
  • the animal growth-promoting agent according to any one of ⁇ 1> to ⁇ 3> above, which is balansae), schinopsis lorentzi, or a combination thereof.
  • the present invention is intended for livestock feed containing the extract of the family Rhus family and a method for raising livestock, and for livestock, including an additive containing the extract of the family Rhus family. feed; ⁇ 6> The livestock feed according to ⁇ 5> above, wherein the extract contains tannin derived from a tree of the family Rhus family in the range of 50 to 100% by weight; ⁇ 7> The livestock feed according to ⁇ 5> or ⁇ 6> above, wherein the extract is an extract extracted from the core material of a tree of the family Rhus family; ⁇ 8> The livestock feed according to any one of ⁇ 5> to ⁇ 7> above, wherein the lacquer tree is schinopsis balansae, schinopsis lorentzi, or a combination thereof; ⁇ 9> The livestock feed according to any one of ⁇ 5> to ⁇ 8>, wherein the content of the animal growth promoter is 0.2 to 1.0% by weight based on the total weight of the feed; ⁇ 10> The livestock feed according to any one of
  • the animal growth promoter and livestock feed of the present invention can be applied to growing pigs and domestic pigs weighing 35 kg or more, in addition to the effect of improving constitution such as antidiarrhea obtained when the feed is given to piglets younger than 2 months old. It has an unprecedented effect that a growth promoting effect can be obtained by administration.
  • the animal growth promoter of the present invention is characterized by containing an extract of a tree of the family Rhus family.
  • extracts of lacquer trees have been mainly used for tanning in the leather industry because they are rich in plant tannins, but in the present invention, surprisingly, lacquer trees such as quebracho have been used. It has been found that the addition of the extract to the feed of livestock has an effect of promoting growth and the like.
  • such an animal growth promoter is expected to be mainly used as an additive for livestock feed, but it is not necessarily limited to such a usage form as long as it is orally ingested by an animal. It is not something that can be done.
  • the Rhus family tree can be widely used as long as the tannin component can be extracted, but is typically a schinopsis balansae, a schinopsis lotnzi, or a combination thereof. be able to. These are a type of tree widely called "Quebracho" and are known to be distributed in a vast area from northern Argentina to western Paraguay in South America. It is preferable that the trunk portion is hard and the specific gravity is about 1.1 to 1.4.
  • the above extract is an extract extracted from the core material of a lacquer tree. Is preferable. In some cases, extracts extracted from other parts such as bark, branches, leaves, fruits, pods and roots can also be included. These extracts contain plant tannins as the main component. Plant tannins are a type of polyphenols contained in plants and are present in solution in the vacuoles of plant tissues (sometimes called catechins).
  • the plant tannins contained in the extract of the lacquer tree belong to the condensed tannins called catechol type. These catechol-based tannins are characterized in that the color of the solution is red to reddish brown, the sugar content is relatively low, and the cohesive force is strong. Further, when it is boiled with formaldehyde or hydrochloric acid, it can precipitate to form a resinous solid substance.
  • the extract of the Rhus family tree in the present invention can preferably contain the tannin component derived from the Rhus family tree in the range of 50 to 100% by weight, more preferably in the range of 70 to 100% by weight. Moreover, it is preferable that the extract is in the form of powder.
  • an extract from a tree of the family Rhus family a known method can be used, but typically, a core material, bark or the like (preferably chipped) is boiled in water to remove insoluble components.
  • An extract can be obtained by treating with sulfite for solubilization and then drying the resulting solution.
  • the obtained dried product is preferably in the form of powder.
  • vegetable oils and fats can be added before the drying step.
  • the animal growth promoter of the present invention may consist only of an extract of the above-mentioned Rhus family tree extract, or may be a mixture containing one or more other carriers.
  • examples of such carriers include soybean flour, wheat flour, calcium carbonate, rice bran, bran, corn flour, cornstarch, rice husks, fish meal, yeast cells and the like.
  • animal fats and oils, or vegetable fats and oils such as soybean oil, coconut oil, canola oil, coconut oil, and olive oil can be added.
  • the animal growth promoter of the present invention when administered to livestock, it may be directly orally administered. Can be taken in. Therefore, the animal growth-promoting agent of the present invention can be formulated and used by a conventional method in an appropriate oral dosage form such as tablets, capsules, granules, pills, pastes and syrups. In some cases, it may be administered as an injection.
  • an aqueous solvent such as distilled water for injection, physiological saline, Ringer's solution or the like can be used.
  • the present invention also relates to a livestock feed containing an additive containing the extract of the cashew family tree.
  • the additive can act as an animal growth promoter capable of promoting the growth of the livestock to which the livestock feed is administered.
  • livestock refers to agricultural animals or livestock animals such as pigs, horses, cows, sheep, or goats raised in farms, pastures, or agricultural environments, or zoos or zoological environments. Means animals that are bred in. It can also include so-called “poultry” such as chickens, quails, ducks and turkeys. Preferably, the livestock is a pig.
  • the livestock feed of the present invention varies depending on the type, age, weight, sex, type of feed, etc. of the livestock, but is usually preferably 0.2% or more, more preferably 0.2% or more by weight, based on the total weight of the feed. It contains 0.2 to 1.0% by weight of the above additive.
  • the livestock feed of the present invention preferably contains nutritional components such as protein, sugar, lipid, and dietary fiber, but grain raw materials or animal-derived raw materials usually used as livestock feed can be used.
  • grain raw materials include wheat, barley, oats, corn, rice, and soybeans.
  • additional nutrients such as vitamins and minerals can be added as needed.
  • the present invention also relates to a method for raising livestock, which comprises administering the above-mentioned livestock feed to livestock.
  • livestock includes various animals such as cows, sheep and horses, but pigs are preferable.
  • the growth stage of the target livestock is not particularly limited, but for example, it can be a pig less than 2 months old during the lactation period, and a growing pig 2 months or more after the weaning period or a weight of 35 kg or more. And can be domestic pigs. Typically, it is preferable that the pig is 2 months old or more or has a body weight of 35 kg or more.
  • the livestock feed of the present invention is given to piglets less than 2 months old, it is suitable for improving the constitution such as antidiarrhea.
  • the elevation of blood leukocytes and the like was suppressed, and histological changes in the small intestine and large intestine were observed.
  • the livestock feed of the present invention is given to a growing pig or a breeding pig having a body weight of 35 kg or more, it is suitable for promoting growth and improving feed efficiency. As shown in the examples, the growth promoting effect was confirmed.
  • the dose of the livestock feed of the present invention is not particularly limited, and can be appropriately set according to the type, age, body weight, sex, type of feed, etc. of the livestock.
  • livestock breeding method of the present invention in addition to the above-mentioned livestock feed, it can be administered in combination with other drugs or feed compounding agents.
  • Quebracho Extract a powdered product purchased from UNITAN (Argentina) was used as it was.
  • the quebracho extract is obtained by boiling the core material of quebracho (schinopsis balansae and schinopsis lorentzi) in water; then treating the solution with sulfite and then adding fats and oils; The resulting solution is dried and pulverized.
  • the obtained dry powder contained about 50% or more of a tannin component.
  • Example of administration to pigs 10 pigs 21 days old were divided into 2 groups (Duroc ⁇ Landrace ⁇ Yorkshire; average body weight 6.51 ⁇ 0.17 kg; experiment start date 21 ⁇ 1d), and the Kebracho extract obtained in 1 above was used.
  • a feed added at 25 g / kg in the feed was prepared, and each group was administered for 110 days for breeding.
  • a feed containing no quebracho extract was given as a control group.
  • the composition of the feed used is shown in Table 1 below.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Husbandry (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Le problème décrit par la présente invention est de fournir un nouveau promoteur de croissance exempt d'antibiotiques pour le bétail qui peut être utilisé en tant que substitut des antibiotiques classiques, et un aliment pour bétail. La solution selon l'invention porte sur un promoteur de croissance animale comprenant un extrait d'arbre anacardiacé.
PCT/JP2021/010781 2020-03-18 2021-03-17 Promoteur de croissance animale et aliment pour bétail WO2021187516A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020-047491 2020-03-18
JP2020047491A JP2023068206A (ja) 2020-03-18 2020-03-18 動物成長促進剤及び家畜用飼料

Publications (1)

Publication Number Publication Date
WO2021187516A1 true WO2021187516A1 (fr) 2021-09-23

Family

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Family Applications (1)

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PCT/JP2021/010781 WO2021187516A1 (fr) 2020-03-18 2021-03-17 Promoteur de croissance animale et aliment pour bétail

Country Status (2)

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JP (1) JP2023068206A (fr)
WO (1) WO2021187516A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004089106A2 (fr) * 2003-04-07 2004-10-21 Luigi Marenchino Melange de tanin servant d'additif
JP2012184285A (ja) * 2011-03-03 2012-09-27 Kagoshima Univ 高分子タンニンの高粘性溶液及びゲルの製造方法
WO2019177171A1 (fr) * 2018-03-16 2019-09-19 味の素株式会社 Additif alimentaire pour animaux et aliment pour animaux

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004089106A2 (fr) * 2003-04-07 2004-10-21 Luigi Marenchino Melange de tanin servant d'additif
JP2012184285A (ja) * 2011-03-03 2012-09-27 Kagoshima Univ 高分子タンニンの高粘性溶液及びゲルの製造方法
WO2019177171A1 (fr) * 2018-03-16 2019-09-19 味の素株式会社 Additif alimentaire pour animaux et aliment pour animaux

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JP2023068206A (ja) 2023-05-17

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