WO2021147211A1 - Module de réaction à écoulement continu, réacteur et unités de garniture - Google Patents

Module de réaction à écoulement continu, réacteur et unités de garniture Download PDF

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Publication number
WO2021147211A1
WO2021147211A1 PCT/CN2020/089539 CN2020089539W WO2021147211A1 WO 2021147211 A1 WO2021147211 A1 WO 2021147211A1 CN 2020089539 W CN2020089539 W CN 2020089539W WO 2021147211 A1 WO2021147211 A1 WO 2021147211A1
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WO
WIPO (PCT)
Prior art keywords
packing
divided
filler
groove
continuous flow
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Application number
PCT/CN2020/089539
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English (en)
Chinese (zh)
Inventor
杨凯
宁萌
张雯
周在国
杨勇
Original Assignee
南通微著智能科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from CN202010063837.6A external-priority patent/CN111111602A/zh
Priority claimed from CN202010368271.8A external-priority patent/CN111468052A/zh
Application filed by 南通微著智能科技有限公司 filed Critical 南通微著智能科技有限公司
Publication of WO2021147211A1 publication Critical patent/WO2021147211A1/fr

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/24—Stationary reactors without moving elements inside
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/32—Packing elements in the form of grids or built-up elements for forming a unit or module inside the apparatus for mass or heat transfer

Definitions

  • the present invention relates to the technical field of continuous flow reaction, in particular, it relates to a reaction module capable of promoting the mixing effect of fluid in a continuous flow process, a reactor equipped with the reaction module and a packing unit in the reaction module.
  • Tubular reactors and tank reactors are currently commonly used fluid reaction equipment in the chemical and pharmaceutical fields.
  • the tank reactor is generally equipped with a stirring device in the reactor for mixing liquid phase reactants, which has the problems of low synthetic purity, low reaction conversion rate, and more serious energy consumption and pollution.
  • the chemical and pharmaceutical fields have high requirements for product purity, continuous flow tubular reactors are relatively more types of reaction equipment.
  • the tubular reactor is generally provided with a tube length that needs to meet the requirements of the chemical reaction.
  • the volume of the entire reactor must be large enough.
  • relevant designs are urgently needed to ensure that the tube length is basically unchanged.
  • microchannel reactor In order to overcome some of the shortcomings of tubular reactors, some reactors with micro-channel structures have been developed in the prior art.
  • the microchannel reactor will be subjected to impact (fluid-fluid, fluid-channel wall), cutting, merging, turbulence, etc. by means of fluid flowing in the microchannel, which is conducive to the mixing of different substances in the fluid during continuous flow. Therefore, compared with the tubular reactor, the microchannel reactor can achieve the purpose of significantly improving the mixing effect of the fluid under the condition that the length is basically equivalent.
  • the structure of the continuous flow reaction module provided by the present invention can strengthen the cutting-mixing effect of the fluid in the flow process, so that the fluid mixing and mass transfer efficiency is significantly enhanced, achieving the purpose of achieving full mixing and high-efficiency mixing.
  • the present invention also relates to a reactor equipped with the reaction module and a filler unit arranged in the reaction module that can affect the cutting-mixing effect.
  • the technical solution of the present invention relates to a continuous flow reaction module, a reactor and a packing unit.
  • a continuous flow reaction module includes an outer tube and a plurality of packing units arranged in the outer tube.
  • the multiple packing units are arranged in sequence in the outer tube.
  • Said packing units include divided screen plates, combined fillers and divided fillers, and are arranged in the order of divided screen plates, combined fillers, and divided fillers, or in the order of combined fillers, divided fillers, and divided screen plates.
  • the downstream end face of the upstream split filler is opposite to the upstream end face of the downstream split screen plate, or between two adjacent packing units, the upstream split screen plate
  • the downstream end face of is opposite to the upstream end face of the downstream merged packing.
  • the spacing between the divided screen plates, the combined packing, and the divided packing in each packing unit can be completely consistent or partially consistent or completely different.
  • the spacing between the opposing surfaces of two adjacent filler units can also take various forms such as all the same, part of the same, or completely different.
  • the inner diameter of the outer tube is controlled in the range of 2 mm to 100 mm, preferably in the range of 5 mm to 20 mm.
  • the side walls of the divided sieve plate, the confluent packing, and the divided packing are in contact with the inner wall of the outer tube, and the contact surfaces are pressed together to ensure the formation of a fixed connection structure.
  • Regular or irregular holes or gaps are formed on the dividing screen plate, so that fluid can flow from one end surface of the dividing screen plate to the other end surface.
  • Grooves are respectively formed on the two end surfaces of the merged filler, and a channel connecting the two grooves is formed between the bottom surfaces of the two grooves.
  • the two end faces of the split filler are provided with grooves at least on the upstream end faces, and are provided with a plurality of channels extending to the edges of the two end faces respectively, and the number of channels can be Two, three, five or eight, the multiple channels are generally evenly distributed around the circumference.
  • the downstream end surface of the split packing may not form a groove structure, that is, (1) between two adjacent packing units, the split packing in the upstream packing unit and the split sieve plate in the downstream packing unit There is a distance between the opposing surfaces; (2) In a packing unit, the opposing surfaces between the confluent filler and the dividing screen are spaced.
  • the formed spacing is relatively small, it is still recommended to form a groove structure on the downstream end surface of the split filler.
  • the fluid enters the channel from the junction of the groove on the upstream end face and the channel port, and flows out to the spacing space at the junction between the edge of the downstream end face and the channel port.
  • the opposing surface between the divided filler and the divided screen plate in the aforementioned case (1) is in contact or there is only a gap formed by assembly, it is necessary to form a groove structure on the downstream end surface of the divided filler.
  • the opposing surfaces between the merged packing and the divided screen plate in the aforementioned case (2) are in contact or there is only a gap formed by assembly, it is also necessary to form a groove structure on the downstream end surface of the divided packing.
  • grooves are formed on both end faces of the split filler. At this time, the two ends of the channel provided on the split filler extend to the edges of the grooves formed on the two end faces. The slots are connected.
  • the equivalent diameter of the holes or gaps formed on the dividing sieve plate is much smaller than the equivalent diameters of the combined packing and the channels provided on the dividing packing.
  • the channel width of the holes or gaps formed on the dividing screen is much smaller than the channel widths of the combined packing and the channels provided on the dividing packing.
  • the thickness or axial dimension of the dividing screen can be set in the range of 0.1 mm to 50 mm, preferably in the range of 1 mm to 5 mm.
  • the radial size (or equivalent diameter) of the holes or gaps formed on the dividing screen may be set in the range of 1 ⁇ m to 800 ⁇ m, preferably in the range of 10 ⁇ m to 200 ⁇ m.
  • the channel changes irregularly over the entire length of the hole or gap, when understanding the aforementioned equivalent diameter, its value is a range interval.
  • the value interval may not be exactly the same, that is, phase Close; the value range of holes or gaps on the dividing screen set at different positions can be different.
  • the dividing sieve plate can be made of porous structure materials, such as sintered metal powder, sintered metal mesh, metal sponge foam, sintered ceramic powder, ceramic sponge foam, laser processed microporous plate, meltblown plastic mesh block, etc.
  • the divided screen, the convergent packing and the divided packing contained therein, and the opposite end faces of the two adjacent ones may be in contact or spaced apart.
  • a converging cavity is formed between the inner wall of the outer tube and the converging filler and/or the dividing screen plate, where the liquid can flow downstream through the channel provided on the converging filler after converging;
  • a reflective mixed flow cavity is formed between the inner wall of the outer tube, the convergent packing and the divided packing. After the liquid flows from the converged cavity into the reflective mixed flow cavity, it will flow radially toward the channel openings provided on the divided packing and flow downstream, during which the liquid will continue to flow.
  • the reflux is cyclically performed to obtain sufficient mixing; a distribution cavity is formed between the inner wall of the outer pipe, the divided filler and the divided sieve plate, and when the liquid flows into the distribution cavity from the reflective mixed flow cavity, It will continue to converge into the cavity in the radial direction, and finally make the liquid re-partition in the cavity on the end surface of the dividing screen, and then continue to flow downstream.
  • the outer diameter of the merged packing is the same as the inner diameter of the outer tube, the axial length of the merged packing is 2mm-20mm, preferably 5-10mm, and the diameter of the upper channel is 0.1mm-5mm, and it needs to be the same as the inner diameter of the outer pipe.
  • the specific value is determined by matching, preferably 0.5-2mm.
  • the outer diameter of the split packing is also the same as the inner diameter of the outer tube, the axial length is 2mm-20mm, preferably 5-10mm, and the number of channels on it is at least 2. More channels need to match the inner diameter of the outer tube and can be designed 10 or even 100, or more, the shape of the channel can be semicircular or irregular in addition to the round hole shape.
  • the axial direction of the through hole can be parallel to the axial direction of the outer tube or form a certain included angle. It plays a role in coarse segmentation.
  • the bottom surface of the groove provided on the end surface of the merged filler is a curved surface.
  • the bottom surface of the groove provided on the end surface of the split filler is an arc surface.
  • one or both end surfaces of the dividing screen may also be provided with arcuate or spherical grooves, and may be one groove or multiple grooves distributed in the surface.
  • downstream end of the channel provided on the merged packing extends to the outside of the bottom surface of the groove on the downstream end surface of the merged packing to form a nozzle, and the port of the nozzle extends to the end of the merged packing located on the downstream end surface. In the groove or extend out of the port of the groove provided on the downstream end surface of the merged filler.
  • the channel provided on the merged packing is a single hole, and the axis of the hole is at the axis of the merged packing.
  • the channels provided on the confluence packing are multiple through holes, one of the through holes is located at the axis of the confluence packing, and the other through holes are distributed around the periphery of the confluence packing, or all the through holes are Set at the periphery of the axis of the confluent packing.
  • the axis of the through hole provided on the periphery of the axis of the merged packing is inclined relative to the axis of the merged packing, and the downstream end is close to the axis of the merged packing.
  • the channel provided on the split filler may be a groove specifically provided on the side wall or a through hole at the inner edge of the side wall.
  • the groove provided on the side wall of the divided filler is a sloping groove, that is, the extending direction of the groove is inclined with respect to the vertical line on the side wall. To the downstream, it is inclined in a direction close to the axis of the divided packing.
  • the groove provided on the side wall of the divided filler is a spiral groove.
  • the through hole at the inner edge of the side wall of the split filler may have an axial extension direction that is consistent with the axial direction of the split filler, or it may be inclined from upstream to downstream toward the axis of the split filler. .
  • the divided sieve plate, the combined packing and the divided packing in the packing unit are connected to one another by a plug-in structure.
  • the split sieve plate, the convergent packing and the split packing in the packing unit are connected to each other by a ring body to form a whole, and preferably the ring body is set as a spiral ring, and the split sieve plate, the convergent packing and the split filler are connected to each other as a whole.
  • the end of the side wall is equipped with external threads to match the spiral ring, so that it is convenient to adjust and control the spacing between the divided sieve plate, the merged filler, and the divided filler.
  • a continuous flow reactor contains the aforementioned continuous flow reaction module, that is, the continuous flow reactor may only contain one form of the aforementioned continuous flow reaction module It can also contain the above-mentioned continuous flow reaction modules in multiple forms at the same time.
  • a packing unit the scheme is: the packing unit includes a divided screen plate, a combined filler and a divided filler, and is arranged in the order of the divided screen, the combined filler, and the divided filler, or the combined filler, the divided filler, and the divided screen. The order of the boards.
  • Regular or irregular holes or gaps are formed on the dividing screen plate, so that fluid can flow from one end surface of the dividing screen plate to the other end surface.
  • Grooves are respectively formed on the two end surfaces of the merged filler, and a channel connecting the two grooves is formed between the bottom surfaces of the two grooves.
  • a groove is formed on at least the upstream end surface of the two end surfaces of the split filler, and a plurality of channels extending to the edges of the two end surfaces respectively are provided at both ends, and the number of the plurality of channels can be It is two, three, four or six.
  • the multiple channels are generally evenly distributed around the circumference, or they may not be evenly distributed.
  • the radial size of the holes or gaps formed on the dividing screen plate is smaller than the radial size of the combined packing and the channels provided on the dividing packing.
  • the channel width of the holes or gaps formed on the dividing screen plate is smaller than the channel widths of the combined packing and the channels provided on the dividing packing.
  • the thickness or axial dimension of the dividing screen can be set in the range of 0.1mm to 50mm, preferably in the range of 1mm to 5mm, such as 1.1mm or 2.3mm or 2.6mm or 4.2mm and so on.
  • the channel width of the holes or slits formed on the dividing screen can be set in the range of 1 ⁇ m to 800 ⁇ m, preferably in the range of 10 ⁇ m to 200 ⁇ m, such as 15 ⁇ m to 60 ⁇ m or 105 microns to 130 microns or 135 microns 180 microns.
  • the dividing sieve plate can be made of porous structure materials, such as sintered metal powder, sintered metal mesh, metal sponge foam, sintered ceramic powder, ceramic sponge foam, laser processed microporous plate, meltblown plastic mesh block, etc.
  • the size of the radial dimension is not a fixed value, but is discrete, even if a connected hole or gap is at different sections of the radial dimension
  • the size can be different.
  • the pore size of each micropore can be different, so the pore size of all micropores is a discrete value that covers an interval.
  • the outer diameter of the merged packing is the same as the inner diameter of the outer tube, the axial length of the merged packing is 2mm-20mm, preferably 5-10mm, and the diameter of the upper channel is 0.1mm-5mm, and it needs to be the same as the inner diameter of the outer pipe.
  • the specific value is determined by matching, preferably 0.5-2mm.
  • the outer diameter of the split packing is also the same as the inner diameter of the outer tube, the axial length is 2mm-20mm, preferably 5-10mm, and the number of channels on it is at least 2. More channels need to match the inner diameter of the outer tube and can be designed 10 or even 100, or more, the shape of the channel can be semicircular or irregular in addition to the round hole shape.
  • the axial direction of the through hole can be parallel to the axial direction of the outer tube or form a certain included angle. It plays a role in coarse segmentation.
  • the divided sieve plate, the convergent packing and the divided packing contained in the packing unit may be in contact with or spaced apart between the opposite end faces of the two adjacent ones.
  • the bottom surface of the groove provided on the end surface of the merged filler is a curved surface.
  • the bottom surface of the groove provided on the end surface of the split filler is an arc surface.
  • one or both of the end faces of the dividing screen may also be provided with curved grooves, and may be one groove or a plurality of grooves distributed in the plane.
  • downstream end of the channel provided on the merged filler extends to the outside of the bottom surface of the groove provided on the downstream end surface of the merged filler to form a nozzle, and the port of the nozzle extends to the end surface of the merged filler on the downstream side.
  • the channel provided on the merged packing is a through hole, and the axis of the through hole is at the axis of the merged packing.
  • the channels provided on the merged packing are multiple through holes, one of the through holes is located at the axis of the merged packing, and the other through holes are distributed on the periphery of the axis of the merged packing. , Or all the through holes are arranged on the periphery of the axis of the confluent packing.
  • the axis of the through hole provided on the periphery of the axis of the merged packing is inclined with respect to the axis of the merged packing, and the downstream end is close to the axis of the merged packing.
  • the channel provided on the split filler may be a groove specifically provided on the side wall or a through hole at the inner edge of the side wall.
  • the groove provided on the side wall of the divided filler is a sloping groove, that is, the extending direction of the groove is inclined with respect to the vertical line on the side wall. To the downstream, it is inclined in a direction close to the axis of the divided packing.
  • the groove provided on the side wall of the divided filler is a spiral groove.
  • the through hole at the inner edge of the side wall of the split filler may have an axial extension direction that is consistent with the axial direction of the split filler, or it may be inclined from upstream to downstream toward the axis of the split filler. .
  • the divided sieve plate, the combined packing and the divided packing in the packing unit are connected to one another by a plug-in structure.
  • the split sieve plate, the convergent packing and the split packing in the packing unit are connected to each other by a ring body to form a whole, and preferably the ring body is set as a spiral ring, and the split sieve plate, the convergent packing and the split filler are connected to each other as a whole.
  • the end of the side wall is equipped with external threads to match the spiral ring, so that it is convenient to adjust and control the spacing between the divided sieve plate, the merged filler, and the divided filler.
  • the beneficial effects of the present invention are: in view of the impact (between fluid-fluid, fluid-channel wall), cutting, merging, turbulence, etc., when fluid flows in the microchannel, so as to promote the mixing of different substances in the fluid, Among them, the most effective function is the cutting-convergence function, which is a kind of forced mixing obtained by using the fluid's own momentum.
  • the purpose of this patent is to provide a structure that can strengthen this function so that the fluid mixing and mass transfer efficiency are compared
  • the macro-mixing has been strengthened thousands of times. Therefore, in general, the patented solution has the effect of strengthening the cutting-mixing effect of the fluid in the flow process, so that the fluid mixing and mass transfer efficiency is significantly enhanced, and the effect of fully mixing and high-efficiency mixing is realized.
  • the sieve plate provided can cut the fluid to the micrometer level, while the ordinary microreactor is only on the millimeter level. Three-dimensional mixing is achieved in three-dimensional space, while ordinary microreactors only achieve two-dimensional mixing in planar space.
  • the module adopts a tubular structure. Compared with the ordinary plate structure, the integral channel formed has a better pressure resistance. Theoretically, it can reach the pressure resistance level of 100 MPa, while the general microreactor can only reach 5 MPa. Up and down, so this patent can greatly improve the safety of the reactor.
  • the pipe end of the module is convenient to seal, which is easy to disassemble and clean.
  • a modular structure is formed, which facilitates the formation of standard parts, facilitates manufacturing, assembly, mass production, and reduces costs.
  • Fig. 1 is a schematic cross-sectional structure diagram of a certain embodiment of a microchannel reaction module.
  • Figure 2.1 is a structural schematic diagram of the state of the packing unit.
  • Figure 2.2 is a schematic diagram of the state two structure of the packing unit.
  • Figure 2.3 is a schematic diagram of the structure of the coarsely divided packing, 2.31 is a top view, and 2.32 is a bottom view.
  • Figure 2.4 is a schematic diagram of the structure of the confluent packing, 2.41 is a top view, and 2.42 is a bottom view.
  • Figure 3.1 is a schematic diagram of the state three structure of the packing unit.
  • Figure 3.2 is a schematic top view of the confluent filler in the embodiment shown in Figure 3.1.
  • Figure 3.3 is a schematic top view of the coarsely divided filler in the embodiment shown in Figure 3.1.
  • Figure 4 is a schematic top view of a certain embodiment of the coarsely divided filler.
  • Figure 5 is a schematic front view of a certain embodiment of the coarsely divided filler.
  • Fig. 6 is a schematic diagram of a three-dimensional structure of a certain embodiment of the coarsely divided filler.
  • Figure 7.1 is a schematic diagram of the state four structure of the packing unit.
  • Figure 7.2 is a schematic diagram of the confluent packing in the embodiment shown in Figure 7.1, 7.21 is a top view, and 7.22 is a bottom view.
  • Figure 7.3 is a schematic diagram of the top view structure of the coarsely divided filler in the embodiment shown in Figure 7.1.
  • Fig. 8 is a schematic diagram of the state five structure of the packing unit.
  • Figure 9 is a schematic diagram of a cross-sectional structure of an embodiment of the confluent filler.
  • FIG. 10 is a schematic cross-sectional structure diagram of another embodiment of the microchannel reaction module.
  • this patent also relates to a continuous flow reaction module.
  • a continuous flow reaction module as shown in FIGS. 1 and 10 includes an outer tube 10 and a plurality of packing units 20 arranged in the outer tube 10.
  • the multiple packing units 20 are sequentially arranged in the outer tube 10.
  • the multiple packing units are arranged in sequence along the axial line of the pipe.
  • the outer tube is a U-shaped tube
  • the multiple packing units are arranged in sequence along the U-shaped bend line.
  • the end of the outer tube may be provided with a connecting structure, such as an external thread and/or an internal thread.
  • the end of the outer tube can be provided with a sealing end cover or one end can be directly provided as an integral sealing structure with the tube.
  • Each packing unit 20 includes dividing screen 1, combined packing 2 and divided packing 3, and is arranged in the order of dividing screen 1, combined packing 2, and divided packing 3 (see Figure 2.1, Figure 2.2, Figure 7.1 and Figure 8), or arranged in the order of combined packing 2, split packing 3, and split sieve plate 1 (see Figure 3.1).
  • the downstream end face of the upstream split packing 3 is opposite to the upstream end face of the downstream split screen 1; or, between two adjacent packing units 20, the upstream split screen
  • the downstream end surface of 1 is opposed to the upstream end surface of the merged packing 2 located downstream.
  • Regular or irregular holes or gaps are formed on the dividing screen plate 1 so that fluid can flow from one end surface of the dividing screen plate 1 to the other end surface (that is, from the end surface on the upstream side to the end surface on the downstream side).
  • a groove one 22 and a groove two 23 are respectively formed on the two end surfaces of the merged packing 2, and a channel 21 connecting the two grooves is formed between the bottom surfaces of the groove one 22 and the groove two 23.
  • the channel 21 provided on the confluence packing 2 is a through hole, and the axis of the through hole is at the axis of the confluence packing 2 (it can be overlapped or not). See the scheme shown in Figure 3.1 to 3.2.
  • the channel 21 provided on the confluence packing 2 is a plurality of through holes. The axis of one through hole is at the axis of the confluence packing 2, and the other through holes are distributed on the axis of the confluence packing 2.
  • all the through holes are arranged on the periphery of the axis of the confluent packing.
  • the axis of the through hole provided on the periphery of the axis of the merged packing is inclined relative to the axis of the merged packing, and the downstream end of the through hole axis is close to the axis of the merged packing.
  • the bottom surface of the groove one 22 and the bottom surface of the groove two 23 provided on the end surface of the merged filler 2 are both arc surfaces (including spherical forms).
  • the arc surface here may be an arc surface with an outer center, or a continuous arc surface formed by a plurality of arc surfaces with multiple outer centers and/or inner centers (as shown in the figure, all belong to this category).
  • the arc shape of the first groove 22 and the arc shape of the second groove 23 may be the same or different.
  • the arc shape of groove one and the arc shape of groove two of the confluent filler contained in different packing units may also be different from each other or may be partially the same.
  • the difference between the first groove and the second groove is mainly reflected in the depth of the groove and the size of the notch, and the notch is preferably a flared form that opens outward.
  • the downstream end of the channel 21 provided on the confluent packing 2 extends to a recess provided on the end face downstream of the confluence packing 2.
  • the nozzle 8 is formed outside the bottom surface of the groove. In other words, the downstream end of the channel one 21 provided on the merged packing 2 extends beyond the bottom surface of the groove two 23 provided on the merged packing 2 to form the nozzle 8.
  • the port of the nozzle extends into the second groove 23 (as shown in FIGS. 8 and 10) or extends out of the port of the second groove 23 (as shown in FIG. 9).
  • the channel 21 with a structure of multiple through holes it may be required that one end of each through hole or one end of a part of the through hole is formed with the nozzle.
  • the free end port of the nozzle can be cone-shaped (large end facing outward or inward).
  • a groove three 32 and a groove four 33 are respectively formed on the two ends of the split filler 3, and a plurality of two channels 31 are also provided on the split filler 3, and the two ends of each channel 31 respectively correspond to the concave grooves.
  • the groove three 32 and the groove four 33 are connected by the channel two 31, that is, a communication relationship is established between the two end faces of the split filler 3, so that the fluid can flow from one end face to the other end face.
  • the bottom surface of the groove three 32 and the bottom surface of the groove four 33 provided on the end surface of the split filler 3 are both arc surfaces (including spherical surfaces).
  • the arc here can be an arc with an outer center, or a continuous arc composed of multiple arcs with multiple outer centers and/or inner centers (as shown in the figure, all belong to this category) .
  • the arc shape of the groove three 32 is different from the arc shape of the groove four 33, but it is not ruled out that they can be the same.
  • the arc shape of groove three and the arc shape of groove four of the divided filler contained in different packing units may also be different from each other or may be partially the same.
  • the depth of groove three is significantly greater than that of groove four.
  • the difference between groove three and groove four can also be reflected in the size of the notch, and the two notches are also preferably in the form of flared openings.
  • the second channel 31 provided on the split filler 3 is specifically a groove provided on the side wall thereof.
  • the groove on the side wall where the split filler 3 is provided can be a straight groove along its measuring line, or a slanted groove with respect to the measuring line, that is, the extending direction of the groove is relative to the (axial) )
  • the vertical line is inclined (as shown in Figure 5).
  • the bottom surface of the groove is inclined, and it is inclined from upstream to downstream in a direction close to the axis of the split filler, as shown in FIG. 5.
  • the groove provided on the side wall of the split filler is a spiral groove (see Figure 6).
  • the grooves constituting the channel two 31 are set in the form of oblique grooves or spiral grooves, so that when multiple fluids converge, they can form reflective impacts in the cavity or converge in the cavity in a rotating state to form a turbulent mixed flow. Collision is generated to strengthen the convergence, so that the different components in the fluid are divided and then collide and converge from the center to re-change the distribution of the components in the fluid, which can further ensure that the fluid is fully and efficiently mixed.
  • the second channel 31 provided on the split filler 3 is specifically arranged in the through hole at the inner edge of the side wall.
  • the through hole at the inner edge of the side wall of the segmented filler may have an axial extension direction consistent with the axial direction of the segmented filler (as shown in the figure), or along the direction from upstream to downstream toward the segment
  • the direction of the packing axis is inclined (the same is to cause multiple streams of fluid to form a reflective impact).
  • the equivalent diameter of the holes or gaps formed on the dividing sieve plate is smaller than the equivalent diameters of the combined packing and the channels one 21 and the channel two 31 provided on the dividing packing.
  • one or both of the end faces of the dividing screen may also be provided with arcuate or spherical grooves, and may be one groove or multiple grooves distributed in the surface.
  • the inner diameter of the outer tube is controlled in the range of 2mm to 100mm, preferably in the range of 5mm to 20mm.
  • the confluence packing 2 is processed by two bowl-shaped groove bottoms on the upper and lower end surfaces to form a circular hole 21.
  • the outer diameter of the confluence packing 2 is the same as the inner diameter of the outer tube 10, and the height (axial direction) of the confluence packing 2
  • the length) is 2mm-20mm, preferably 5-10mm, and the diameter of the channel 21 is 0.1mm-5mm, which matches the inner diameter of the corresponding outer tube, preferably 0.5-2mm.
  • the split filler 3 is composed of bowl-shaped depressions on the upper and lower end surfaces and two channels 31 at the outer edges.
  • the two channels 31 contain a plurality of round holes.
  • the outer diameter of the split filler 3 is the same as the inner diameter of the outer tube 10, and the height (axial length) is 2mm-20mm, preferably 5-10mm.
  • the number of circular holes (ie, coarsely divided channels) constituting the second channel 31 is at least 2. More channels need to match the inner diameter of the outer tube 10, and 10 or even 100 or more can be designed.
  • the shape can also be semicircular or irregular.
  • the axial direction of the through hole can be parallel to the axial direction of the outer tube or form a certain included angle, in order to achieve a coarse division effect.
  • the dividing sieve may be made of porous structure materials, such as sintered metal powder, sintered metal mesh, metal sponge foam, sintered ceramic powder, ceramic sponge foam, laser processed microporous plate, melting Spray plastic net blocks and so on.
  • the thickness (axial length) of the dividing screen can be set in the range of 0.1 mm to 50 mm, preferably in the range of 1 mm to 5 mm.
  • the radial size (or channel width) of the holes or gaps formed on the dividing screen may be set in the range of 1 ⁇ m to 800 ⁇ m, preferably in the range of 10 ⁇ m to 200 ⁇ m.
  • each packing unit the divided sieve, confluent packing, and divided packing contained in it may be in contact or spaced between the opposite end faces of the two adjacent ones, as shown in Figure 1 to Figure 2.2.
  • the space L1, L2... etc. can be the same or partly different.
  • the side walls of the dividing screen 1, the merged packing 2, and the divided packing 3 are all in contact with the inner wall of the outer tube 10.
  • the hot assembly process is mostly used to make the sidewalls of the split screen 1, the converging packing 2, the split packing 3 and the inner wall of the outer tube are pressed together to ensure that the split screen 1, the confluence packing 2, and the split packing are in use. 3 Will not move relatively in the lumen.
  • the dividing sieve plate 1, the merged packing 2, and the divided packing 3 can also be arranged correspondingly outside the outer pipe so that the dividing sieve plate 1,
  • the side walls of the merged packing 2 and the divided packing 3 are pressed together with the inner wall of the outer tube.
  • the outer tube referred to can be understood as a plurality of unit tubes connected together by a threaded structure or a plug-in structure. At this time, the opposite ends of the two unit tubes that are connected should meet the requirements of the packing unit in the entire outer tube. Layout law.
  • the outer tube is set in a unit form, which can be easily assembled, and it is convenient to put the divided screen 1, the merged packing 2, and the divided packing 3 into the tube, and it is convenient to grasp the axial distance between two adjacent packing units during operation.
  • a confluence chamber 4 is formed between the inner wall of the outer tube 10 and the confluent packing 2 and/or the dividing sieve plate 1, where the fluid (or liquid) can flow downstream through the channel 21 provided on the confluence packing 2 after converging here.
  • the inner wall of the outer tube 10 and the confluence filler 2 and the split filler 3 form a reflective mixed flow cavity 5. After the liquid flows from the converged cavity 4 into the reflective mixed flow cavity 5, it will radially toward the channel two provided on the split filler 3 The 31 port flow is roughly divided into multiple strands and then flows downstream. During this period, the liquid will continue to be reflected by the bottom surface of the two grooves (groove two 23 and groove three 32) of the reflective mixed flow cavity 5, and return cyclically.
  • a distribution cavity 6 is formed between the inner wall of the outer tube 10, the dividing filler 3 and the dividing sieve plate 1.
  • the packing unit 20 is arranged in the order of the divided screen plate 1, the combined packing 2, and the divided packing 3. Therefore, when flowing in from the inlet end of the outer tube 10, the fluid first passes through the holes or gaps on the dividing screen 1 and is forcibly sheared into small multiple strands before flowing to the confluence cavity 4. Then the fluid enters the reflective mixed flow cavity 5 from the confluence cavity 4 through the channel one 21, and collides with the reflective wall formed by the bottom wall of the groove two 23 and the groove three 32, and is bounced by the reflective wall and mixed with the upper fluid nowadays impact.
  • the ground is roughly divided into n fluids by channel two 31.
  • the n fluids flow into the distribution cavity, they are evenly distributed on the end surface of the dividing sieve plate 1, enter the gaps in the dividing sieve plate, and are further divided into micron-level poles. Multi-path fluids, these small fluids enter the downstream confluence chamber 4 again through the dividing screen, where they converge and mix in the cavity, and enter the reflective mixing chamber 5 of the downstream stage through the channel of the downstream stage. Line to achieve efficient mixing and mass transfer.
  • the nozzle 8 is formed at the downstream port of the channel 21, the reflection frequency and impact intensity in the reflection mixing cavity 5 can be strengthened, and the reflection mixing effect can be further improved.
  • the split screen 1, the combined filler 2 and the split filler 3 in the packing unit 20 are connected to each other as a whole through a plug-in structure (see Figure 7.1 to Figure 7.3), or
  • the split sieve plate 1, the merged packing 2 and the split packing 3 in the packing sheet 20 are connected to each other as a whole through the ring body 7, and preferably the ring body 7 is set as a spiral ring, and the split sieve plate 1 ,
  • the end of the side wall of the merged packing 2 and the split packing 3 are equipped with external threads to match the screw ring. This arrangement is convenient to adjust and control the spacing between the split sieve plate 1, the merged packing 2, and the split packing 3 (see Figure 8. Figure 10).
  • the spacing between the divided screen 1, the combined packing 2, and the divided packing 3 in each packing unit 20 can be completely Consistent or partially consistent or completely different.
  • the spacing between the opposing faces of the two adjacent filler units 20 (such as L1, L2.. in the figure) can also be the same or partly the same or completely different.
  • this patent also relates to a continuous flow reactor, in which the involved continuous flow reaction module is applied. That is, the continuous flow reactor includes the continuous flow reaction module mentioned above.
  • the continuous flow reactor may contain only one type of continuous flow reaction module mentioned above, or it may contain multiple types of continuous flow reaction modules mentioned above at the same time.
  • the continuous flow reactor also includes a heat exchange fixture or a heat exchange shell placed on the periphery of the outer tube 10.
  • this patent also relates to a packing unit, which is an important part of the continuous flow reaction module involved.
  • the dividing sieve plate 1 can be made of porous structure materials, such as sintered metal powder, sintered metal mesh, metal sponge foam, sintered ceramic powder, ceramic sponge foam, laser processed microporous plate, meltblown plastic mesh block, etc. Therefore, regular or irregular holes or gaps can be formed on the dividing screen plate, and the purpose is to ensure that the fluid can flow from one end surface of the dividing screen plate to the other end surface through the holes or gaps in the body.
  • porous structure materials such as sintered metal powder, sintered metal mesh, metal sponge foam, sintered ceramic powder, ceramic sponge foam, laser processed microporous plate, meltblown plastic mesh block, etc. Therefore, regular or irregular holes or gaps can be formed on the dividing screen plate, and the purpose is to ensure that the fluid can flow from one end surface of the dividing screen plate to the other end surface through the holes or gaps in the body.
  • the thickness of the dividing sieve plate 1 can be set in the range of 0.1 mm to 50 mm, preferably in the range of 1 mm to 5 mm, such as 1.1 mm or 2.3 mm or 2.6 mm or 4.2 mm.
  • the radial size (or channel width) of the holes or gaps formed on the dividing sieve plate 1 can be set in the range of 1 ⁇ m to 800 ⁇ m, preferably in the range of 10 ⁇ m to 200 ⁇ m, such as 15 ⁇ m or 60 ⁇ m or 105 microns or 130 microns or 180 microns.
  • the size of the radial dimension is not a fixed value, but is discrete, even if a connected hole or gap is at different sections of the radial dimension
  • the size can be different.
  • the pore size of each micropore can be different, so the pore size of all micropores is a discrete value that covers an interval. For the understanding of a specific value given above, it can be considered that it represents an average value or a central value (the specific value fluctuates up and down relative to the central value).
  • a groove one 22 and a groove two 23 are respectively formed on the two end surfaces of the merged packing 2, and a channel 21 connecting the two grooves is formed between the bottom surfaces of the groove one 22 and the groove two 23.
  • the channel 21 can be a cylindrical hole, a prismatic hole, a semi-cylindrical hole or a special-shaped hole.
  • the height (axial length) of the confluent filler 2 is 2mm-20mm, preferably 5-10mm, and the diameter of the channel 21 is 0.1mm-5mm, preferably 0.5-2mm. If the diameter of the hole in this section is a non-circular hole, it should be understood according to the equivalent diameter.
  • a groove three 32 and a groove four 33 are respectively formed on the two ends of the split filler 3, and at the same time, there are two ends respectively extending to the notches of the two grooves and connecting the two grooves.
  • the height (axial length) of the split filler 3 is 2mm-20mm, preferably 5-10mm.
  • the number of circular holes (ie, coarsely divided channels) constituting the second channel 31 is at least two, and more channels can be designed with 10, or even 100, or more under the necessary external structure size.
  • the cavity shape of the channel two 31 can also be a semi-cylindrical or prismatic hole or an irregular hole or groove.
  • the diameter of pores, gaps, cavities, channels, etc. if they are non-circular holes, they are all understood in terms of equivalent diameters. It can be seen that the equivalent diameter of the holes or gaps formed on the dividing sieve plate 1 is much smaller than the equivalent diameters of the combined packing and the channels provided on the dividing packing.
  • the groove bottom surfaces of the groove one 22 and the groove two 23 provided on the end surface of the merged packing 2 are both arc surfaces (including spherical surfaces).
  • the groove bottom surfaces of the groove three 32 and the groove four 33 provided on the end surface of the split filler 3 are arc surfaces (including spherical surfaces).
  • the arc here can be an arc with an outer center, or a continuous arc composed of multiple arcs with multiple outer centers and/or inner centers (as shown in Figs. 1 to 10) Such).
  • the arc shape of the first groove 22 and the arc shape of the second groove 23 may be the same or different.
  • the arc shape of the groove three 32 and the arc shape of the groove four 33 may be the same or different.
  • the arc shape of groove one and the arc shape of groove two of the confluent filler contained in different packing units may also be different from each other or may be partially the same.
  • the difference between the first groove and the second groove is mainly reflected in the depth of the groove and the size of the notch, and the notch is preferably a flared form that opens outward.
  • the arc shape of groove three and the arc shape of groove four of the divided filler contained in different packing units may also be different from each other or may be partially the same.
  • the difference between groove three and groove four is mainly reflected in the depth of the groove and the size of the groove, and the groove is preferably a flared form that opens outward.
  • the groove depth of groove three 32 is obviously greater than that of groove four 33, and the notch of groove three 32 is smaller than that of groove 334.
  • One or two end surfaces of the dividing screen plate can also be set with arcuate or spherical grooves, and can be one groove or multiple grooves distributed in the surface.
  • the downstream end of the channel 21 provided on the combined packing 2 extends to the outside of the bottom surface of the groove provided on the end face downstream of the combined packing 2 to form a nozzle 8.
  • the downstream end of the channel one 21 extends to the outside of the bottom surface of the groove two 23 on the confluence packing 2 to form a nozzle 8.
  • the port of the nozzle extends into the second groove 23 (as shown in FIGS. 8 and 10) or extends out of the port of the second groove 23 (as shown in FIG. 9).
  • the channel 21 with a structure of multiple through holes it may be required that one end of each through hole or one end of a part of the through hole is formed with a nozzle.
  • the free end port of the nozzle can be cone-shaped (large end facing outward or inward).
  • the structure of the nozzle 8 extending outward is provided to more effectively converge and eject the fluid.
  • the good fluid enters the downstream cavity to form a reflection and mixed flow state, so as to better achieve the purpose of being uniformly mixed again.
  • the cavity of the channel 21 can be designed according to the principle of the Venturi tube.
  • the channel 21 provided on the combined packing 2 is a single hole, and the axis of the hole is at the axis of the combined packing.
  • the channel 21 provided on the confluence packing 2 is a plurality of circular holes
  • the axis of one of the circular holes is at the axis of the confluence packing 2
  • the other circular holes are distributed and arranged on the periphery of the axis of the confluence packing.
  • all the circular holes can also be arranged on the periphery of the axis of the confluent packing, distributed around the circle or distributed in a cross shape or an X shape, and other forms.
  • the axis of the circular hole provided on the periphery of the axis of the merged packing is inclined relative to the axis of the merged packing, and the downstream end is close to the axis of the merged packing.
  • it is a channel 21 with a plurality of circular holes, one end of each circular hole or one end of a partial circular hole is formed with the nozzle 8 described above.
  • the second channel 31 provided on the split packing 3 is specifically a plurality of grooves provided on the side wall thereof.
  • the groove provided on the side wall of the split filler may be a slanted groove, that is, the extending direction of the groove is inclined with respect to the (axial) vertical line on the side wall, or more preferably, the bottom surface of the groove is The inclined surface is inclined from upstream to downstream in a direction close to the axis of the divided packing (as shown in Figure 6).
  • the grooves provided on the sidewalls of the split filler may also be spiral grooves (as shown in FIG. 5).
  • Setting the grooves that constitute the channel two 31 into a chute or spiral groove can make multiple fluids converge to form a reflection collision or converge in a rotating state, forming a turbulent mixed flow, and different particles in the fluid can collide and strengthen the confluence.
  • the function enables the different components in the fluid to be split and then collide and converge, which re-changes the distribution of each component in the fluid, and can further ensure that the fluid is fully and efficiently mixed.
  • the second channel 31 provided on the split filler 3 is specifically a plurality of through holes provided at the inner edge of the side wall.
  • each through hole at the inner edge of the side wall of the split filler may have its axis extending in the same direction as the axis of the split filler (as shown in the figure), or along the direction from upstream to downstream toward the partition closer to the partition.
  • the direction of the packing axis is inclined (the same is to cause multiple streams of fluid to form a reflective impact).
  • the divided screen 1, the combined packing 2 and the divided packing 3 in the packing unit 20 are connected to each other as a whole through a plug-in structure.
  • An annular flange 24 is provided at the edge of the upstream end surface of the combined packing 2, and the downstream end of the dividing screen 1 is inserted into the flange 24, so that the dividing screen 1 and the combined packing 2 are plug-connected and connected as a whole .
  • a plurality of arc-shaped slots 25 are provided at the edge of the downstream end face of the converging filler 2, and the upstream end face of the split filler 3 is formed with inserts 34 corresponding to the slots 25, so that the confluence The packing 2 and the split packing 3 are plug-connected and connected as a whole.
  • the split screen 1, the combined packing 2 and the split packing 3 in the packing unit 20 are connected to each other by a ring body 7 to form a whole, and the ring body 7 is preferably set as a screw. Rings are equipped with external threads on the sidewall ends of the dividing screen 1, the converging packing 2 and the dividing packing 3 to match the screw ring. This arrangement is convenient for adjusting and controlling the spacing between the dividing screen, the confluence packing and the dividing packing.

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

L'invention concerne un module de réaction à écoulement continu, un réacteur et des unités de garniture. Le module de réaction à écoulement continu comprend un tuyau externe (10) et une pluralité d'unités de garniture agencées en séquence dans le tuyau externe (10). Chaque unité de garniture comprend une plaque perforée de séparation (1), une garniture de convergence (2) et une garniture de séparation (3). Des trous ou des espaces sont formés dans la plaque perforée de séparation (1), de telle sorte qu'un fluide peut s'écouler à travers les deux surfaces d'extrémité de celle-ci. Des évidements (22, 23) sont formés dans les deux surfaces d'extrémité de la garniture de convergence (2), et un canal (21) est formé entre les surfaces de fond des évidements. Un évidement (32, 33) est formé dans au moins une surface d'extrémité de la garniture de séparation (3), et la garniture de séparation (3) est munie d'une pluralité de canaux (31) faisant communiquer les deux surfaces d'extrémité de celle-ci. Le diamètre équivalent des trous ou des espaces de la plaque perforée de séparation (1) est plus petit que le diamètre équivalent des canaux sur la garniture de convergence (2) et la garniture de séparation (3). Une cavité de convergence (4), une cavité d'écoulement mixte par réflexion (5), et une cavité de distribution (6) peuvent être définies par la paroi interne du tuyau externe (10), les surfaces d'extrémité de la plaque perforée de séparation (1), de la garniture de convergence (2), et de la garniture de séparation (3), et les évidements dans les surfaces d'extrémité ; le fluide s'écoule en séquence parmi les cavités et est soumis en continu et de manière circulaire à une action de découpe-convergence.
PCT/CN2020/089539 2020-01-20 2020-05-11 Module de réaction à écoulement continu, réacteur et unités de garniture WO2021147211A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN202010063837.6 2020-01-20
CN202010063837.6A CN111111602A (zh) 2020-01-20 2020-01-20 连续流反应模块、反应装置及填块
CN202010368271.8 2020-05-01
CN202010368271.8A CN111468052A (zh) 2020-05-01 2020-05-01 一种连续流反应模块、反应器及填料单元

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WO2021147211A1 true WO2021147211A1 (fr) 2021-07-29

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2081698C1 (ru) * 1995-04-18 1997-06-20 Владимир Ильич Смирнов Насадка ректификационной колонны
RU2339442C2 (ru) * 2006-10-03 2008-11-27 Государственное образовательное учреждение высшего профессионального образования Воронежское высшее военное авиационное инженерное училище (военный институт) Насадка ректификационной колонны
CN104258795A (zh) * 2014-09-24 2015-01-07 中国纺织科学研究院 交换反应系统、包含其的改性聚酯生产系统及改性聚酯生产方法
CN109876688A (zh) * 2019-04-16 2019-06-14 青岛三易安化工设备有限公司 流体混合装置
CN111111602A (zh) * 2020-01-20 2020-05-08 南通微著智能科技有限公司 连续流反应模块、反应装置及填块

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2081698C1 (ru) * 1995-04-18 1997-06-20 Владимир Ильич Смирнов Насадка ректификационной колонны
RU2339442C2 (ru) * 2006-10-03 2008-11-27 Государственное образовательное учреждение высшего профессионального образования Воронежское высшее военное авиационное инженерное училище (военный институт) Насадка ректификационной колонны
CN104258795A (zh) * 2014-09-24 2015-01-07 中国纺织科学研究院 交换反应系统、包含其的改性聚酯生产系统及改性聚酯生产方法
CN109876688A (zh) * 2019-04-16 2019-06-14 青岛三易安化工设备有限公司 流体混合装置
CN111111602A (zh) * 2020-01-20 2020-05-08 南通微著智能科技有限公司 连续流反应模块、反应装置及填块

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