WO2021125785A3 - 면역 크로마토그래피용 스트립, 키트 및 이를 이용하는 경쟁적 면역 크로마토그래피 분석 방법 - Google Patents

면역 크로마토그래피용 스트립, 키트 및 이를 이용하는 경쟁적 면역 크로마토그래피 분석 방법 Download PDF

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Publication number
WO2021125785A3
WO2021125785A3 PCT/KR2020/018443 KR2020018443W WO2021125785A3 WO 2021125785 A3 WO2021125785 A3 WO 2021125785A3 KR 2020018443 W KR2020018443 W KR 2020018443W WO 2021125785 A3 WO2021125785 A3 WO 2021125785A3
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WO
WIPO (PCT)
Prior art keywords
ligand
conjugate
pad
immunochromatographic
control line
Prior art date
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PCT/KR2020/018443
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English (en)
French (fr)
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WO2021125785A2 (ko
Inventor
김정연
최동섭
안준엽
임국진
김범종
Original Assignee
(주)프로테옴텍
경기도 여주시
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Application filed by (주)프로테옴텍, 경기도 여주시 filed Critical (주)프로테옴텍
Priority to EP20901022.2A priority Critical patent/EP4080212A4/en
Priority to BR112022011852A priority patent/BR112022011852A2/pt
Priority to AU2020406822A priority patent/AU2020406822A1/en
Publication of WO2021125785A2 publication Critical patent/WO2021125785A2/ko
Publication of WO2021125785A3 publication Critical patent/WO2021125785A3/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

본 발명은 액상 검체를 수용하는 검체패드, 검체패드의 일측에 연결되며 표지물질 및 표적물질 유사체를 수용하는 접합체패드, 상기 접합체패드의 일측에 연결되며 검사선, 제1 대조선 및 제2 대조선을 포함하는 검출패드 및 상기 검출패드의 일측에 연결되며 반응 후 잔존하는 액상을 수용하는 흡습패드를 포함하고, 상기 검사선은 제1 리간드를 포함하며, 상기 제1 리간드는 표적물질 및 제1 접합체와 반응할 수 있고, 상기 제1 대조선은 제2 접합체와 반응하는 제2-1 리간드를 포함하며, 상기 제2 대조선은 제2 접합체와 반응하는 제2-2 리간드를 포함하되, 상기 제2-1 리간드와 상기 제2-2 리간드의 농도는 서로 상이하여 검체 내 표적물질의 정성적 분석 및 정량적 분석을 편리하게 수행할 수 있는 면역 크로마토그래피용 스트립을 제공한다.
PCT/KR2020/018443 2019-12-16 2020-12-16 면역 크로마토그래피용 스트립, 키트 및 이를 이용하는 경쟁적 면역 크로마토그래피 분석 방법 WO2021125785A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP20901022.2A EP4080212A4 (en) 2019-12-16 2020-12-16 IMMUNOCHROMATOGRAPHIC STRIP AND KIT AND COMPETITIVE IMMUNOCHROMATOGRAPHIC ANALYSIS METHOD THEREFOR
BR112022011852A BR112022011852A2 (pt) 2019-12-16 2020-12-16 Tira imunocromatográfica e kit, e método de análise imunocromatrográfica competitiva que usa os mesmos
AU2020406822A AU2020406822A1 (en) 2019-12-16 2020-12-16 Immunochromatographic strip and kit, and competitive immunochromatographic analysis method using same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2019-0168246 2019-12-16
KR1020190168246A KR102346178B1 (ko) 2019-12-16 2019-12-16 면역 크로마토그래피용 스트립, 키트 및 이를 이용하는 경쟁적 면역 크로마토그래피 분석 방법

Publications (2)

Publication Number Publication Date
WO2021125785A2 WO2021125785A2 (ko) 2021-06-24
WO2021125785A3 true WO2021125785A3 (ko) 2021-08-12

Family

ID=76476809

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2020/018443 WO2021125785A2 (ko) 2019-12-16 2020-12-16 면역 크로마토그래피용 스트립, 키트 및 이를 이용하는 경쟁적 면역 크로마토그래피 분석 방법

Country Status (5)

Country Link
EP (1) EP4080212A4 (ko)
KR (1) KR102346178B1 (ko)
AU (1) AU2020406822A1 (ko)
BR (1) BR112022011852A2 (ko)
WO (1) WO2021125785A2 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113848330B (zh) * 2021-11-30 2022-03-15 山东子峰生物技术有限公司 一种同型半胱氨酸和维生素b12的检测方法、检测试纸条及其应用
CN114778833B (zh) * 2022-06-22 2022-09-27 北京芯迈微生物技术有限公司 基于竞争性免疫分析的定量检测试剂盒及方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020014004A (ko) * 2000-08-12 2002-02-25 장진동 정상 임신과 자궁외 임신을 진단하는 장치 및 이의제조방법
US20120021531A1 (en) * 2008-06-04 2012-01-26 Jayne Ellis Assay Reader, Device and Method of Measuring HCG
KR20140143120A (ko) * 2013-06-04 2014-12-15 (주)프로테옴텍 가변 대조선을 구비한 분석 스트립 및 이를 구비한 진단 키트
KR20160108695A (ko) * 2015-03-05 2016-09-20 (주)프로테옴텍 이종 검사선을 구비한 임신진단용 면역크로마토그래피 스트립 및 이를 구비한 임신 진단 키트
KR20190027755A (ko) * 2017-09-07 2019-03-15 (주)프로테옴텍 다수의 검사선을 구비한 크로마토그래피용 스트립, 이를 포함하는 진단 키트 및 다수의 경쟁적 반응 측정 단계를 포함하는 정성, 반정량, 정량 분석방법

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AU5688398A (en) * 1996-11-27 1998-06-22 Schleicher & Schuell, Inc. Competitive lateral flow, specific binding chromatographic assay devices, kits , and methods
US6767710B2 (en) * 2001-03-30 2004-07-27 Praxsys Biosystems, Llc Prewetting stop flow test strip
US8455263B2 (en) * 2008-12-30 2013-06-04 Jin Po Lee Quantitative analyte assay device and method

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020014004A (ko) * 2000-08-12 2002-02-25 장진동 정상 임신과 자궁외 임신을 진단하는 장치 및 이의제조방법
US20120021531A1 (en) * 2008-06-04 2012-01-26 Jayne Ellis Assay Reader, Device and Method of Measuring HCG
KR20140143120A (ko) * 2013-06-04 2014-12-15 (주)프로테옴텍 가변 대조선을 구비한 분석 스트립 및 이를 구비한 진단 키트
KR20160108695A (ko) * 2015-03-05 2016-09-20 (주)프로테옴텍 이종 검사선을 구비한 임신진단용 면역크로마토그래피 스트립 및 이를 구비한 임신 진단 키트
KR20190027755A (ko) * 2017-09-07 2019-03-15 (주)프로테옴텍 다수의 검사선을 구비한 크로마토그래피용 스트립, 이를 포함하는 진단 키트 및 다수의 경쟁적 반응 측정 단계를 포함하는 정성, 반정량, 정량 분석방법

Also Published As

Publication number Publication date
BR112022011852A2 (pt) 2022-09-06
KR102346178B1 (ko) 2022-01-03
KR20210076746A (ko) 2021-06-24
EP4080212A2 (en) 2022-10-26
WO2021125785A2 (ko) 2021-06-24
AU2020406822A1 (en) 2022-06-30
EP4080212A4 (en) 2024-02-28

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