WO2021101111A3 - 고순도 가교 히알루론산 제조 장치 및 방법 - Google Patents

고순도 가교 히알루론산 제조 장치 및 방법 Download PDF

Info

Publication number
WO2021101111A3
WO2021101111A3 PCT/KR2020/014872 KR2020014872W WO2021101111A3 WO 2021101111 A3 WO2021101111 A3 WO 2021101111A3 KR 2020014872 W KR2020014872 W KR 2020014872W WO 2021101111 A3 WO2021101111 A3 WO 2021101111A3
Authority
WO
WIPO (PCT)
Prior art keywords
space
container
hyaluronic acid
mixture
manufacturing high
Prior art date
Application number
PCT/KR2020/014872
Other languages
English (en)
French (fr)
Other versions
WO2021101111A2 (ko
Inventor
이희영
Original Assignee
메디칸 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 메디칸 주식회사 filed Critical 메디칸 주식회사
Publication of WO2021101111A2 publication Critical patent/WO2021101111A2/ko
Publication of WO2021101111A3 publication Critical patent/WO2021101111A3/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

본 발명의 하나의 실시예에 관한 고순도 가교 히알루론산 제조 장치는 용기, 분산 부재, 가압 부재 및 분리 부재를 구비한다. 용기는 히알루론산, 가교제 및 물을 포함하는 혼합물이 수용되는 부재이다. 분산 부재는, 용기 내에 배열되어 용기 내부를 제1 공간과 제2 공간으로 구획하며 혼합물이 제1 공간에서 제2 공간으로 또는 제2 공간에서 제1 공간으로 이동할 때에 통과함으로써 혼합물에 포함된 히알루론산이 집적된 물질을 분산시켜 가교제와 혼합되도록 하는 부재이다. 가압 부재는 용기 내에 이동가능하게 배열되어 혼합물이 제1 공간에서 제2 공간으로 또는 제2 공간에서 제1 공간으로 이동하도록 혼합물을 가압하는 가압 부재이다. 분리 부재는 가압 부재가 이동할 때에 용기 내벽과 접촉함으로써 용기 내벽에 잔류하는 물질을 용기 내벽으로부터 분리시키는 부재이다.
PCT/KR2020/014872 2019-11-20 2020-10-29 고순도 가교 히알루론산 제조 장치 및 방법 WO2021101111A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020190149310A KR102313200B1 (ko) 2019-11-20 2019-11-20 고순도 가교 히알루론산 제조 장치 및 방법
KR10-2019-0149310 2019-11-20

Publications (2)

Publication Number Publication Date
WO2021101111A2 WO2021101111A2 (ko) 2021-05-27
WO2021101111A3 true WO2021101111A3 (ko) 2021-07-15

Family

ID=75981311

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2020/014872 WO2021101111A2 (ko) 2019-11-20 2020-10-29 고순도 가교 히알루론산 제조 장치 및 방법

Country Status (2)

Country Link
KR (2) KR102313200B1 (ko)
WO (1) WO2021101111A2 (ko)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05230105A (ja) * 1992-02-21 1993-09-07 Nok Corp 重合方法および重合装置
JPH11228836A (ja) * 1998-02-10 1999-08-24 Shin Etsu Chem Co Ltd 液状シリコーンゴムベースの製造方法
JP2007511296A (ja) * 2003-11-18 2007-05-10 ボストン　サイエンティフィック　リミテッド 複合成分でなる骨接合剤用の混合および供給器具
KR20070083570A (ko) * 2004-11-15 2007-08-24 가부시키가이샤 시세이도 가교 히알루론산 겔의 제조 방법
JP2016037039A (ja) * 2014-08-05 2016-03-22 横浜ゴム株式会社 ゴム組成物の混合方法および混合システム
WO2017036597A1 (en) * 2015-09-01 2017-03-09 Merz Pharma Gmbh & Co. Kgaa Method of making a cross-linked polymer gel and device for performing the method
WO2019026939A1 (ja) * 2017-08-01 2019-02-07 本田技研工業株式会社 液体混合装置及び液体混合方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05230105A (ja) * 1992-02-21 1993-09-07 Nok Corp 重合方法および重合装置
JPH11228836A (ja) * 1998-02-10 1999-08-24 Shin Etsu Chem Co Ltd 液状シリコーンゴムベースの製造方法
JP2007511296A (ja) * 2003-11-18 2007-05-10 ボストン　サイエンティフィック　リミテッド 複合成分でなる骨接合剤用の混合および供給器具
KR20070083570A (ko) * 2004-11-15 2007-08-24 가부시키가이샤 시세이도 가교 히알루론산 겔의 제조 방법
JP2016037039A (ja) * 2014-08-05 2016-03-22 横浜ゴム株式会社 ゴム組成物の混合方法および混合システム
WO2017036597A1 (en) * 2015-09-01 2017-03-09 Merz Pharma Gmbh & Co. Kgaa Method of making a cross-linked polymer gel and device for performing the method
WO2019026939A1 (ja) * 2017-08-01 2019-02-07 本田技研工業株式会社 液体混合装置及び液体混合方法

Also Published As

Publication number Publication date
KR20210101190A (ko) 2021-08-18
WO2021101111A2 (ko) 2021-05-27
KR102313200B1 (ko) 2021-10-15
KR20210061585A (ko) 2021-05-28
KR102532935B1 (ko) 2023-05-16

Similar Documents

Publication Publication Date Title
WO2016032344A3 (en) Process and apparatus for separating valuable or harmful liquids from slurries
CA2983184A1 (en) Separation of metal-organic frameworks
EP3912713A4 (en) RAW MATERIALS MIXER
WO2012018596A3 (en) Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution
PH12019500767A1 (en) Method for recycling polyolefin containing waste
EP3685912A3 (en) Powder processing apparatus for classifying and degassing
WO2018174693A3 (ko) 순간 유화 화장품 제조 장치 및 제조 방법
EP3326723A4 (en) DISCHARGE DEVICE AND DISCHARGE PROCESS FOR LIQUID MATERIAL WITH SOLIDS PARTICLES AND COATING DEVICE
PH12020551004A1 (en) Transform selection in a video encoder and/or video decoder
CN102277104A (zh) 橡胶型压敏胶粘剂及其制备方法与应用
WO2021101111A3 (ko) 고순도 가교 히알루론산 제조 장치 및 방법
MY197471A (en) Process for preparation of polyethylene nanocomposite
EP3765392C0 (en) VACUUM PLATE, SHEET MATERIAL HANDLING APPARATUS INCLUDING SUCH VACUUM PLATE, AND METHOD OF MAKING THE PLATE
WO2018182433A3 (en) Method for recovering liquids from slurries
ZA200708360B (en) Acquisition process of stoppers from mixed material agglomerate
US2193887A (en) Strand handling apparatus
US3620417A (en) Package-dispensing device
JPS51111989A (en) Nethod and apparatus for pressing nonmetallic material
CN105333186B (zh) 采用自动控制系统的新型泄爆阀
WO2018020053A3 (en) A threaded closure
CA3093536A1 (en) Mixing device comprising a seal
PH12019501141A1 (en) Volatilization apparatus
SG11201903075WA (en) Process for treating gasoline
GB2557127A (en) Apparatus and method for separating liquid from a material comprising a solid fraction and a liquid fraction
WO2022005144A3 (ko) 테이프 캐스팅 방식을 적용한 평판형 세라믹 분리막 제조방법

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20891350

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 20891350

Country of ref document: EP

Kind code of ref document: A2