WO2020186748A1 - Dry towel, processing method therefor and application thereof - Google Patents

Dry towel, processing method therefor and application thereof Download PDF

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Publication number
WO2020186748A1
WO2020186748A1 PCT/CN2019/112459 CN2019112459W WO2020186748A1 WO 2020186748 A1 WO2020186748 A1 WO 2020186748A1 CN 2019112459 W CN2019112459 W CN 2019112459W WO 2020186748 A1 WO2020186748 A1 WO 2020186748A1
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WO
WIPO (PCT)
Prior art keywords
freeze
dried
extract
fiber
film layer
Prior art date
Application number
PCT/CN2019/112459
Other languages
French (fr)
Chinese (zh)
Inventor
李和伟
Original Assignee
李和伟
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 李和伟 filed Critical 李和伟
Publication of WO2020186748A1 publication Critical patent/WO2020186748A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10General cosmetic use

Definitions

  • the invention relates to the technical field of sticking products, in particular to a dry towel and its processing method and application.
  • most of the active ingredients are In liquid state, there are problems such as unstable active ingredients and containing additives. In addition, it needs to be used on the surface or repeatedly wiped during use. When the active ingredients are transferred to the skin surface, they will not form a film, volatilize quickly, and dissolve and absorb through the skin slowly.
  • the purpose of the present invention is to solve the problem of inconvenience in the use of dry towels in the prior art, and to provide a dry towel. After the dry towel meets with water, the active ingredients are dissolved or dissolved, and a film can be formed on the epidermis with one rub. Easy to use, save time and effort.
  • Another object of the present invention is to provide a processing technology of the dry towel.
  • the processing technology adopts a processing method of dipping, spraying and then freeze-drying, or melt coating and then freeze-drying.
  • the technology is simple and convenient for commercial promotion and application.
  • Another object of the present invention is to provide a package of the dry towel, which can provide a good sealing environment and has a moisture-proof function.
  • Another object of the present invention is to provide the application of the dry towel, which can be applied to skin care products, makeup remover and cleansing products, transdermal absorption external medicine patches or wound dressing patches.
  • a dry towel comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel being in contact with 0.0001ml/cm 2 -0.1ml/cm 2 of water,
  • the freeze-dried film can be dissolved or dissolved out.
  • the dissolution or dissolution time is 3-10s
  • the freeze-dried film layer can be either layered to form a freeze-dried layer on the surface of the base fabric carrier layer, or partially or completely embedded in the base fabric carrier layer Freeze-dried layer.
  • the skin care and medicinal active ingredients are integrated into the freeze-dried film through a special process to form an adult freeze-dried, which has an excellent protective effect, and due to the loose and porous structure after freeze-drying, the freeze-dried film can be formed with a small amount of water. It quickly collapses the structure, dissolves and dissolves, and due to the evaporation of body temperature, it quickly dehydrates into a film on the epidermis, which has the corresponding skin care or medicinal dressing effect.
  • the freeze-dried film layer After the freeze-dried film layer is compounded with the base fabric carrier layer, the freeze-dried film layer has good toughness to prevent damage during the production process and cause cost waste, and protect the morphological integrity during logistics and shelf life.
  • the thickness of the freeze-dried film layer is 0.1 ⁇ m-300 ⁇ m.
  • the dry towel further includes a release layer.
  • the release layer plays a further protective role to protect the integrity of the freeze-dried film layer and improve hygiene.
  • the release layer is located on one side of the base fabric carrier layer, which can be located on the side of the freeze-dried film layer or the side opposite to the freeze-dried film.
  • the release layer can also be provided with two layers on the base fabric carrier layer On both sides.
  • the shape of the base fabric carrier layer is circular, square, polygonal or irregular
  • the base fabric carrier layer can be expanded or compressed
  • the material of the base fabric carrier layer is non-woven One or more blends of cloth, absorbent cotton, cotton fiber, bamboo fiber, seaweed fiber, tencel, cupra, and modal fiber.
  • the release layer is a composite of one or more of pet, pe, pu, bopp, pvc, pp, and aluminum foil.
  • the shape and size of the release layer can be the same as the shape and size of the base fabric carrier layer. The release layer is discarded before use, and then the base fabric carrier layer and the freeze-dried film layer are in contact with water.
  • the freeze-dried film layer includes one or a combination of freeze-dried efficacy substances, freeze-dried skin feel agents, or freeze-dried fibers.
  • the freeze-dried product is an active ingredient for skin care and medicine.
  • the freeze-dried skin feel agent can be swelled and dissolved by adding a small amount of water. If necessary, freeze-dried fibers (such as freeze-dried collagen silk) can be further added for film-forming fixation.
  • freeze-dried film layer includes freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers
  • the quality of the freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers The ratio is (1-30): (0.1-50): (0.1-100);
  • the mass ratio of the freeze-dried functional substance and the freeze-dried skin feel agent is (1-30): (0.1-30);
  • the mass ratio of the freeze-dried functional substances and freeze-dried fibers is (1-100): (0.4-100);
  • the mass ratio of the freeze-dried skin feel agent and the freeze-dried fiber is (1-100): (0.2-1000).
  • the freeze-dried effect is selected from one or a combination of western medicine ingredients, traditional Chinese medicine ingredients, natural extracts, biologically active ingredients, and skin care beneficial ingredients
  • the freeze-dried skin feel agent is selected from protein , Polysaccharides and their salts, high molecular polymers, polyols, natural and synthetic oils and fats, or a combination of surfactants
  • the freeze-dried fiber is collagen fiber, chitosan fiber, seaweed One or a combination of salt fiber, algae shell blend fiber and carboxymethyl cellulose fiber.
  • the western medicine components in the freeze-dried effect are ketoprofen, ibuprofen, naphazoline, diclofenac diethylamine, ketoconazole, hydrocortisone, miconazole, clobetasol, trichomidine, Resorcinol, the traditional Chinese medicine ingredients are borneol, mint, camphor, licorice, scutellaria, turmeric, rhubarb, sulfur, sophora flavescens, cranberry, coptis, cork, calamine, zinc oxide, and the natural extract is orange Cortin extract, Canadian red maple extract, Scutellaria baicalensis root extract, Sapindus extract, fatty acid amide alkyl betaine, Centella asiatica extract, acerola cherry extract, peony root extract, lotus extract, Snow lotus extract, ginseng root extract, cucumber fruit extract, aloe leaf extract, portulaca extract, sweet oregano leaf extract, elderberry extract, rose extract, seaweed extract, truffle extract
  • the protein in the freeze-dried skin feel agent is soluble glycoprotein, collagen or hydrolyzed gelatin, and the polysaccharide is fructan, xanthan gum, sodium hyaluronate, polyglutamic acid, and carbohydrate isomers Body, tremella polysaccharide or trehalose, the polyol is propylene glycol, glycerin, butylene glycol or caprylyl, the natural and synthetic oils are petrolatum, oleyl alcohol, caprylic/capric triglyceride or hydrogenated palm oil ,
  • the high molecular polymer is sodium polyacrylate or carbomer, and the surfactant is polyglycerol-10 glyceride, polyglycerol-10-stearate, polysorbate 80, coco-beet Alkali, sodium lauroyl glutamate or fatty acid amide alkyl betaine.
  • the dry towel is processed by the following method:
  • Step 1 Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent
  • Step 2 The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
  • Step 3 Coat on the surface of the base cloth, freeze-dry at -50°C ⁇ -30°C;
  • Step 1 Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
  • Step 2 The freeze-dried film is combined with the base fabric
  • Step 1 Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the base fabric, and freeze-dry at -50°C to -30°C;
  • Step 2 Compound with the release layer to form the final product.
  • Step 1 Add water or aqueous solution to the freeze-dried fiber, freeze-dried at -50°C to -30°C, and blend and compound with the base fabric;
  • Step 2 Compound with the release layer to form the final product.
  • the freeze-dried film layer when the dry towel is in contact with water, the freeze-dried film layer is dissolved or dissolved, and then when contact or friction occurs with the epidermis, the freeze-dried film layer is peeled off from the base fabric carrier layer, and a film is formed on the epidermis .
  • the present invention also includes the application of the dry towel as a skin care product, a make-up remover cleaning product, a transdermal absorption external medication patch or a wound dressing patch.
  • the dissolved or eluted freeze-dried product remains on the skin as an essential skin care dry towel. It can also be used as a makeup remover and cleansing towel by dissolving makeup and stains on the skin surface during wiping, which is milder than conventional makeup remover. Not glaring.
  • the dissolved or eluted lyophilized product can be left on the skin for transdermal absorption and used as an external medicine to avoid contamination of the bottled after opening.
  • the lyophilized product can be dissolved or dissolved after wiping. It is used as a dressing that remains on the skin wound and isolates the wound from the external environment, and used as a liquid wound dressing to avoid contamination of ordinary liquid dressings after opening.
  • the packaging of the dry towel also includes the packaging of the dry towel. It can be selected from one of single independent packaging and multiple collective packaging;
  • the single independent packaging can be a packaging with moisture barrier and sealing properties, such as one of bag, box, blister, and bottle , Preferably one of aluminum-plastic blister pack, hard aluminum small box, capsule coffee pack, glass packaging, and metal packaging;
  • the multiple assembly packaging may be a packaging with moisture barrier and sealing properties, such as bag or box One or a combination of packaging, blister packaging, and bottle packaging, preferably one of aluminum-plastic blister packaging, hard aluminum small box, capsule coffee packaging, glass packaging, metal packaging, plastic bottle, plastic box, aluminum-plastic bag Or combination.
  • the “multiple assembly packaging” can be multiple dry towels stacked or mixed and packaged in one outer package, or single or multiple packages are packaged into one sub package, and multiple sub packages are packaged in one outer package.
  • the "piece” refers to an independent individual, which can be in the form of a sheet, a crimp, or a compressed form according to the shape of the carrier layer of the dry towel base fabric.
  • freeze-dried film layer formed on a base cloth carrier layer in a freeze-dried form
  • the freeze-dried film layer comprising a freeze-dried functional substance and/or a freeze-dried skin feel agent and/or a freeze-dried Fiber component
  • the freeze-dried effect is selected from one or a combination of western medicine ingredients, traditional Chinese medicine ingredients, natural extracts, biologically active ingredients, and skin care beneficial ingredients
  • the freeze-dried skin feel agent is selected from protein , Polysaccharides and their salts, high molecular polymers, polyols, natural and synthetic oils and fats, or a combination of surfactants
  • the freeze-dried fiber is collagen fiber, chitosan fiber, seaweed One or a combination of salt fiber, algae shell blend fiber and carboxymethyl cellulose fiber.
  • freeze-dried film layer includes freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers
  • the quality of the freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers The ratio is (1-30): (0.1-50): (0.1-100);
  • the mass ratio of the freeze-dried functional substance and the freeze-dried skin feel agent is (1-30): (0.1-30);
  • the mass ratio of the freeze-dried functional substances and freeze-dried fibers is (1-100): (0.4-100);
  • the mass ratio of the freeze-dried skin feel agent and freeze-dried fiber is (1-100): (0.2-1000)
  • the western medicine components in the freeze-dried product are ketoprofen, ibuprofen, naphazoline, diclofenac diethylamine, ketoconazole, hydrocortisone, miconazole clobeta
  • the traditional Chinese medicine ingredients are borneol, menthol, camphor, licorice, scutellaria, turmeric, rhubarb, sulfur, sophora flavescens, cranberry, coptis, cork, calamine, zinc oxide
  • the natural extracts are hesperidin extract, Canadian red maple extract, Scutellaria baicalensis root extract, Sapindus extract, fatty acid amide alkyl betaine, Centella asiatica extract, Acerola cherry extract, Paeonia lactiflora root extract Extracts, lotus extract, yacon extract, ginseng root extract, cucumber fruit extract, aloe leaf extract, portulaca extract, sweet oregano leaf extract, elderberry extract, rose extract, seaweed extract
  • the protein in the freeze-dried skin feel agent is soluble glycoprotein, collagen or hydrolyzed gelatin, and the polysaccharide is fructan, xanthan gum, sodium hyaluronate, polyglutamic acid, and carbohydrate isomers Body, tremella polysaccharide or trehalose, the polyol is propylene glycol, glycerin, butylene glycol or caprylyl, the natural and synthetic oils are petrolatum, oleyl alcohol, caprylic/capric triglyceride or hydrogenated palm oil ,
  • the high molecular polymer is sodium polyacrylate or carbomer, and the surfactant is polyglycerol-10 glyceride, polyglycerol-10-stearate, polysorbate 80, coco-beet Alkali, sodium lauroyl glutamate or fatty acid amide alkyl betaine.
  • freeze-dried film layer is prepared by the following steps:
  • Step 1 Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent
  • Step 2 The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
  • Step 3 Freeze drying at -50°C ⁇ -30°C;
  • Step 1 Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
  • Step 1 Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent
  • Step 2 The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
  • Step 3 Spray the above mixture on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
  • Step 1 Add water or aqueous solution to the freeze-dried fiber, freeze-dry it at -50°C to -30°C.
  • Another aspect of the present invention includes a method for processing dry towels, including the following steps:
  • Step 1 Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent
  • Step 2 The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
  • Step 3 Coat on the surface of the base cloth, freeze-dry at -50°C ⁇ -30°C;
  • Step 1 Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
  • Step 2 The freeze-dried film is combined with the base fabric
  • Step 1 Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the base fabric, and freeze-dry at -50°C to -30°C;
  • Step 2 Compound with the release layer to form the final product
  • Step 1 Add water or aqueous solution to the freeze-dried fiber, freeze-dried at -50°C to -30°C, and blend and compound with the base fabric;
  • Step 2 Compound with the release layer to form the final product.
  • the freeze-dried film layer includes freeze-dried functional substances and/or freeze-dried skin feel agents and/or freeze-dried fiber components, wherein the freeze-dried functional substances are selected from western medicine ingredients, traditional Chinese medicine ingredients, One or a combination of natural extracts, biologically active ingredients, skin care beneficial ingredients, the freeze-dried skin feel agent is selected from the group consisting of proteins, polysaccharides and their salts, high molecular polymers, polyols, natural and synthetic One or a combination of oils and surfactants, the freeze-dried fiber is one of collagen fiber, chitosan fiber, seaweed salt fiber, algae shell blend fiber, carboxymethyl cellulose fiber or combination.
  • the freeze-dried functional substances are selected from western medicine ingredients, traditional Chinese medicine ingredients, One or a combination of natural extracts, biologically active ingredients, skin care beneficial ingredients
  • the freeze-dried skin feel agent is selected from the group consisting of proteins, polysaccharides and their salts, high molecular polymers, polyols, natural and synthetic One
  • the western medicine components in the freeze-dried product are ketoprofen, ibuprofen, naphazoline, diclofenac diethylamine, ketoconazole, hydrocortisone, miconazole clobeta
  • the traditional Chinese medicine ingredients are borneol, menthol, camphor, licorice, scutellaria, turmeric, rhubarb, sulfur, sophora flavescens, cranberry, coptis, cork, calamine, zinc oxide
  • the natural extracts are hesperidin extract, Canadian red maple extract, Scutellaria baicalensis root extract, Sapindus extract, fatty acid amide alkyl betaine, Centella asiatica extract, Acerola cherry extract, Paeonia lactiflora root extract Extract, lotus extract, snow lotus extract, ginseng root extract, cucumber fruit extract, aloe leaf extract, portulaca extract, sweet oregano leaf extract, elderberry extract, rose extract, seaweed extract , Tru
  • the protein in the freeze-dried skin feel agent is soluble glycoprotein, collagen or hydrolyzed gelatin, and the polysaccharide is fructan, xanthan gum, sodium hyaluronate, polyglutamic acid, and carbohydrate isomers Body, tremella polysaccharide or trehalose, the polyol is propylene glycol, glycerin, butylene glycol or caprylyl, the natural and synthetic oils are petrolatum, oleyl alcohol, caprylic/capric triglyceride or hydrogenated palm oil ,
  • the high molecular polymer is sodium polyacrylate or carbomer, and the surfactant is polyglycerol-10 glyceride, polyglycerol-10-stearate, polysorbate 80, coco-beet Alkali, sodium lauroyl glutamate or fatty acid amide alkyl betaine.
  • the active ingredients in the dry towel of the present invention are attached to the carrier layer of the base cloth in a freeze-dried form, and the dry towel will not be exposed to moisture during storage and transportation. Therefore, the dry towel does not add preservatives and antibacterial agents. The safety factor is high.
  • the active ingredients in the dry towel of the present invention are attached to the carrier layer of the base cloth in a freeze-dried form, which effectively maintains the heat sensitivity or the activity of the easily unstable ingredients and improves the use effect.
  • freeze-dried film layer has a "porous" component structure, some normal thickeners originally need to be swollen and dissolved. Because of the porousness, the extremely strong expansion and water contact area and efficiency make it a short time and a small amount of water. It can be effective.
  • the freeze-dried film layer of the dry towel can be dissolved in a small amount (0.0001ml/cm 2 -0.1ml/cm 2 ) of water, so that the packaging volume of the dry towel can be reduced, and it is suitable for special applications under the condition of less water.
  • the packaging volume also needs to be adapted to the water demand.
  • the dry towel requires less water and the packaging can be reduced accordingly.
  • a small amount of water can promote the dissolution or dissolution of the active ingredients to achieve the effect, so the damage is less and safer, it is more convenient to carry and use, and the dissolution and transdermal absorption are stronger.
  • Freeze-dried effects freeze-dried skin feel agents and freeze-dried fibers are not strong enough to bind the carrier layer of the base fabric.
  • Freeze-dried skin feel agents such as soluble glycoprotein, fructan, propylene glycol, hydrogenated palm oil, sodium polyglutamate, and freeze-dried fibers such as collagen fiber and chitosan fiber have this characteristic, so they can all "Matrix, but it also has "film-forming properties", so it can "break away from the matrix” and then "form a film.”
  • a dry towel wet it with a small amount of water and wipe it on the epidermis.
  • the freeze-dried film layer is peeled off from the carrier layer of the base cloth and dehydrated on the epidermis to form a film again.
  • the corresponding effect is achieved, the method of use is simple, and the inconvenience caused by long-term wearing is avoided.
  • a dry towel comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel is in contact with 0.01 ml/cm 2 of water, the freeze-dried film layer It can be dissolved within 10s, and the dissolution rate of the lyophilized product can reach more than 90% within 1 min.
  • the thickness of the freeze-dried film layer is 100 ⁇ m.
  • the shape of the base fabric carrier layer is a circular non-woven fabric
  • the freeze-dried film layer includes freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers
  • the freeze-dried functional substances are milk protein, acetyl six Peptide-1, Bacillus fermentation product
  • the freeze-dried skin feel agent is sodium hyaluronate
  • sodium polyglutamate is collagen fiber.
  • the dry towel is processed by the following method:
  • Step 1 Mix 10% milk protein, 0.02% acetyl hexapeptide-1, 0.1% bacillus fermented product, 0.1% sodium hyaluronate, 0.05% sodium polyglutamate, and dissolve it in water, with 600-800g Sprayed on the surface of 45g/m2 collagen fiber at a ratio of /m2, fully infiltrated, and freeze-dried in vacuum at -50°C ⁇ -30°C to form a 100 ⁇ m thick lyophilized film;
  • Step 2 The freeze-dried film is combined with the pure cotton non-woven fabric to form the essence dry towel.
  • the dry towel in this embodiment is used as an essence dry towel for skin care.
  • first contact the dry towel with water to dissolve or dissolve the lyophilized film layer and then when rubbing against the epidermis, the lyophilized film layer is peeled off from the carrier layer of the base cloth and forms a film on the epidermis.
  • the essence can be Play the role of skin care.
  • the packaging structure of the dry towel in this embodiment is a multi-piece assembled plastic box with an aluminum plastic bag on the outside.
  • the mass ratio of the freeze-dried efficacy substance, the freeze-dried skin feel agent, and the freeze-dried fiber is adjusted.
  • step 1 is adjusted to: 9% milk protein, 0.5% acetyl hexapeptide-1, 0.5%
  • the fermentation product of Bacillus, 0.9% sodium hyaluronate and 0.1% sodium polyglutamate are thoroughly mixed and dissolved in water, and sprayed on the surface of the collagen fiber of 10g/m2 at a ratio of 1000g/m2. After fully infiltrating, proceed to -50 °C ⁇ -30°C vacuum freeze drying.
  • the obtained essence dry towel has the same effect.
  • An ordinary essence mask the formula is water (to 100%), 10% milk protein, 0.02% acetyl hexapeptide-1, 0.1% bacillus fermentation product, 0.1% sodium hyaluronate, 0.05% sodium polyglutamate , 0.5% phenoxyethanol, 0.2% methyl paraben, 0.2% polysorbate 80.
  • the membrane cloth is pure cotton non-woven cloth, and the packaging is generally in a multi-piece plastic box.
  • the ingredients When used, because the ingredients contain preservatives, it will cause a certain irritation to the epidermis, and it will sting after accidentally entering the eyes.
  • the tracking test results for the content of milk protein and acetyl hexapeptide-1 show that after the product is packaged, the dry towel of Example 1 and the facial mask of Comparative Example 1 are placed in the same cool storage for 1 year, the milk in Example 1
  • the content loss of protein and acetyl hexapeptide-1 is less than 5%
  • the milk protein loss of comparative example 1 is 20%
  • the acetyl hexapeptide-1 loss is 35%; there is a significant difference in the stability of the active substance.
  • a rapid skin moisture detector was used to detect the moisture content of the epidermis. After the dry towel in Example 1 was wiped 5 times (15s), the moisture content of the epidermis increased from the initial value of 28% to 56%; the facial mask in Comparative Example 1 After 15s, the skin moisture content increased from the initial value of 28% to 32%. After 5 minutes of application, the skin moisture content increased from the initial value of 28% to 53%. It can be seen that the essence dry towel can effectively improve skin hydration due to its rapid film formation on the skin surface.
  • Moisturizing essence wet wipes (brand: Li Dezi, commercially available): Its formula contains: water, butylene glycol, propylene glycol, dipropylene glycol (preservative), 1,2 hexanediol (preservative), portulaca Extract, Allantoin, Caprylic Capric Triglyceride, Ethylhexyl Glycerin, Tremella Extract, Xylitol, Disodium EDTA, Gluconolactone, Papaya Fruit Extract, Glucose, Salicylic Acid.
  • the commercially available wet wipes contain a large amount of antiseptic polyols, which are irritating, and there is no film formation after wiping, and they will evaporate quickly, making it difficult for the essence to stay.
  • a dry towel comprising a base fabric carrier layer, a freeze-dried film layer and a release layer attached to the base fabric carrier layer in a freeze-dried form, the dry towel is in contact with 0.1 ml/cm 2 of water, the The shape of the base fabric carrier layer is a square non-woven fabric, and the material is Tencel.
  • the freeze-dried film layer can be dissolved within 5 seconds, and the dissolution rate of the freeze-dried functional substance reaches more than 90% within 1 min.
  • the thickness of the freeze-dried film layer is 300 ⁇ m.
  • the freeze-dried film layer is a freeze-dried functional substance, and the freeze-dried functional substance is a Sapindus extract, coco-betaine, sodium lauroyl glutamate, and sodium acetylated hyaluronate; the release layer It is consistent with the shape and size of the base cloth carrier layer, and the material is pu.
  • the dry towel is processed by the following method:
  • Step 1 Dissolve 15% soapberry extract, 5% coco-betaine, 3% sodium lauroyl glutamate, and 0.1% sodium acetylated hyaluronate in water, defoam and spray on the surface of the base cloth, Carry out -50°C ⁇ -30°C vacuum freeze-drying to form a freeze-dried film layer after 300 ⁇ m;
  • Step 2 Compound with the release layer to form the final product.
  • the dry towel in this embodiment is used as a makeup remover and cleansing towel.
  • first contact the dry towel with water to dissolve or dissolve the freeze-dried film layer and then when wiping with the epidermis, the freeze-dried film layer is peeled off from the base cloth carrier layer, and a film is formed on the epidermis.
  • It can dissolve makeup, stains, etc. on the skin's surface and use it as a dry wipe for cleansing makeup, and can further clean the face.
  • the packaging structure of the dry towel in this embodiment is a multi-piece assembled aluminum-plastic bag.
  • Comparative Example 2-1 Use the similar formula of Example 2 to make.
  • a cleansing water containing water (to 100%), 15% Sapindus extract, 5% coco betaine, 3% sodium lauroyl glutamate, 0.1% sodium acetylated hyaluronate, 0.3% Methyl isothiazolinone.
  • each piece absorbs about 5g of the above makeup remover water, and the single use amount for makeup remover is 6 makeup remover pads. After use, it needs to be cleaned with facial cleanser. Due to extensive exposure to surfactants, the skin becomes dry, the stratum corneum becomes thinner, and sensitive to other skin problems after daily makeup removal.
  • Example 2 Using the cleansing dry towel of Example 2, 2 pieces are needed for a single cleansing. After dissolving on the skin surface and forming a film, add water again to use as a facial cleanser, which greatly reduces the amount of surfactant contact with the skin and protects the skin's water and oil balance .
  • Makeup remover cleansing sheet wipes (brand: Qinye, commercially available): Its formula contains: water, sodium lauroyl glutamate, potassium lauroyl glutamate, sodium cocoyl glutamate, PVP/PVA vinyl propionate Ester copolymer, royal jelly, glycerin, pyrrolidone carboxylic acid, butanediol, phenoxyethanol, grape leaf extract, witch hazel extract, mallow extract, cucumber fruit extract, aloe vera leaf extract, Hypericum perforatum extract.
  • the commercially available wet wipes are in the form of wet wipes, they need to be added with water each time they are used. Only after 3 sheets are used on one side can they have a clear makeup removal effect.
  • the formula contains phenoxyethanol preservatives, which have irritating effects on the skin.
  • a dry towel comprising a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form, the dry towel is in contact with 0.0005 ml/cm 2 of water, the freeze-dried film layer It can be dissolved in 7s, and the dissolution rate of the lyophilized product can reach more than 90% in 1 min.
  • the shape of the base fabric carrier layer is a square non-woven fabric, and the material is a composite material of absorbent cotton and pure cotton non-woven fabric, and the thickness of the freeze-dried film layer is 5 ⁇ m.
  • the freeze-dried film layer includes a freeze-dried functional substance and a freeze-dried skin feel agent.
  • the freeze-dried functional substance is a small molecule sodium hyaluronate; the freeze-dried skin feel agent is hydrogenated palm oil and polyglyceryl oleate.
  • the dry towel is processed by the following method:
  • Step 1 Disperse the small molecule sodium hyaluronate in hydrogenated palm oil with a mass ratio of 1:9;
  • Step 2 Heat the mixture to 47°C to melt until it has fluidity, and add polyglycerol oleate, the ratio of which to the mixture is 1:1;
  • Step 3 Coating on the surface of the base fabric and performing vacuum freeze drying at -50°C to 20°C to solidify the mixture and remove moisture absorption to form a 5 ⁇ m thick freeze-dried film.
  • the dry towel in this embodiment is used as a dressing patch.
  • first contact the dry towel with minimal exudate in the wound or water vapor emitted from the skin the freeze-dried film layer is dissolved or dissolved, the freeze-dried film layer is peeled from the base cloth carrier layer, and the skin wound , Form a film on the isolated wound to form a liquid wound patch.
  • the packaging structure of the dry towel in this embodiment is a single-piece aluminum-plastic bag.
  • Step 1 Disperse small molecule sodium hyaluronate in hydrogenated palm oil, the dispersion masses were 10g and 0.2g respectively; Step 2. Heat the mixture to 47 Melt at °C to fluidity, add 0.8g of polyglycerol oleate; Step 3. Coat on the surface of the base fabric, and freeze-dry at -50°C-20°C to make the mixture solidify and remove moisture to form 5 ⁇ m Thick freeze-dried film.
  • the obtained liquid wound patch has the same effect.
  • Comparative Example 3 Using the similar formula of Example 3 to make.
  • a liquid wound plaster contains 5% polyglycerol oleate, 4.5% hydrogenated palm oil, 0.5% small molecule sodium hyaluronate, 0.5% p-hydroxyacetophenone, and water (to 100%). It is necessary to squeeze 5-10g into the affected area during use, and the package is difficult to reseal. The shelf life of the package is 2 months after opening.
  • a dry towel comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel is in contact with 0.001 ml/cm 2 of water, and the base cloth carrier layer
  • the shape of is a square non-woven fabric, and the material is a blend of cupra fiber and modal fiber.
  • the freeze-dried film layer can be dissolved within 3s, and the dissolution rate of the freeze-dried functional substance reaches more than 90% within 1 min.
  • the thickness of the freeze-dried film layer is 0.1 ⁇ m.
  • the freeze-dried film layer includes a freeze-dried functional substance, a freeze-dried skin feel agent and a freeze-dried fiber, the freeze-dried functional substance is ketoprofen, the freeze-dried skin feel agent is carbomer and glycerin, and the freeze-dried The dry fiber is chitosan fiber.
  • the dry towel is processed by the following method:
  • Step 1 Dissolve ketoprofen 1%, carbomer 0.5% and glycerol 10% with water (to 100%), adjust the pH to 5.5 and have a certain gel viscosity (>300cp), and then use the ratio of 200-350g/m2 Coated on the surface of 50g/m2 chitosan fiber and freeze-dried in vacuum at -50°C ⁇ -25°C to form a freeze-dried film layer;
  • Step 2 The freeze-dried film layer is combined with the cupra/modal blended fabric base fabric to form a dry towel for external pain medication.
  • the dry towel in this embodiment is used as a transdermal external medication patch.
  • the dry towel is first contacted with a small amount of water (such as the emitted water vapor contact), the freeze-dried film layer is dissolved or dissolved, and then when rubbing with the skin, the freeze-dried film layer and the base fabric carrier layer are peeled off , It forms a film on the epidermis, and the active ingredients are used in the form of transdermal absorption.
  • the packaging structure of the dry towel in this embodiment is a single piece of aluminum-plastic blister pack.
  • step 1 The ingredients in step 1 are adjusted on the basis of this example.
  • the adjusted step 1 is: dissolve ketoprofen 1%, carbomer 5% and glycerol 45% with water (to 100%), and adjust the pH to 5.5 After having a certain gel viscosity (>300cp), it is coated on the surface of 100g/m2 chitosan fiber at a ratio of 100g/m2, and freeze-dried under vacuum at -50°C ⁇ -25°C to form a freeze-dried film layer.
  • step 1 after adjustment Dissolve ketoprofen 1%, carbomer 5% and glycerol 45% with water (to 100%), adjust the pH to 5.5 and have a certain gel viscosity (>300cp), and then use 100g/ The ratio of m2 is coated on the surface of 0.1g/m2 chitosan fiber, and it is vacuum freeze-dried at -50°C ⁇ -25°C to form a freeze-dried film layer. On the basis of this adjustment, transdermal topical medicinal patches with the above effects can be obtained.
  • step 1 after adjustment Dissolve ketoprofen 30%, carbomer 5% and glycerol 45% with water (to 100%), adjust the pH to 5.5 and have a certain gel viscosity (>300cp), and then use 100g/ The ratio of m2 is coated on the surface of 0.1g/m2 chitosan fiber, and it is vacuum freeze-dried at -50°C ⁇ -25°C to form a freeze-dried film layer. On the basis of this adjustment, transdermal topical medicinal patches with the above effects can be obtained.
  • step 1 after adjustment Dissolve ketoprofen 30%, carbomer 5% and glycerol 45% with water (to 100%), adjust the pH to 5.5 and have a certain gel viscosity (>300cp), and then use 100g/ The ratio of m2 is coated on the surface of 100g/m2 chitosan fiber and freeze-dried in vacuum at -50°C ⁇ -25°C to form a freeze-dried film layer.
  • transdermal topical medicinal patches with the above effects can be obtained.
  • Ketoprofen 1%, carbomer 0.5% and glycerol 10% are dissolved in water (to 100%), adjusted to pH 5.5 and have a certain gel viscosity (>300cp), and then directly coated on the surface of chitosan fiber with copper Ammonia/Modal blended fabric is compounded and packaged for external use.
  • a dry towel comprising a release layer, a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form.
  • the dry towel is in contact with 0.05 ml/cm 2 of water, and the The lyophilized film layer can be dissolved in 6 seconds, and the dissolution rate of the lyophilized product can reach more than 90% within 1 min.
  • the shape of the base fabric carrier layer is an oval non-woven fabric, the material is 30% seaweed fiber, the shape and size of the release layer are the same as the base fabric carrier layer, and the material is pet.
  • the thickness is 30 ⁇ m.
  • the freeze-dried film layer includes a freeze-dried functional substance, a freeze-dried skin feel agent, and a freeze-dried fiber
  • the freeze-dried functional substance is nicotinamide, a scutellaria root extract
  • the freeze-dried skin feel agent is a soluble glycoprotein, a poly Sorbitol ester 80, caprylic acid/capric acid triglyceride
  • the freeze-dried fiber is 35 g/m2 carboxymethyl cellulose fiber.
  • the dry towel is processed by the following method:
  • Step 1 Dissolve nicotinamide 3%, Scutellaria baicalensis root extract 1%, soluble glycoprotein 1%, polysorbate 80 1.5%, caprylic acid/capric triglyceride 2% in water, emulsify and homogenize, and 35g/ m2 Carboxymethyl cellulose fibers infiltrate each other and freeze-dried in vacuum at -50°C ⁇ -25°C to form a freeze-dried film layer
  • Step 2 The freeze-dried film layer is combined with the seaweed fiber base cloth carrier to form a dry skin lightening essence towel.
  • the dry towel in this embodiment is used as a skin care essence dry towel.
  • the membrane serves the purpose of skin care.
  • the packaging structure of the dry towel in this embodiment is a sealed bag.
  • each component in step 1 was adjusted, specifically, nicotinamide 0.9%, scutellaria root extract 0.1%, soluble glycoprotein 0.01%, polysorbate 80 0.07%, caprylic acid/ Capric triglyceride 0.02% is dissolved in water and emulsified uniformly.
  • the 100g emulsified mixture is infiltrated with 100g/m2 carboxymethyl cellulose fiber 1m 2 and freeze-dried under vacuum at -50°C ⁇ -25°C to form Freeze-dried film layer; the skin care essence dry towel obtained by this has the same effect as the above.
  • Niacinamide 0.2% Scutellaria baicalensis root extract 0.1%, soluble glycoprotein 0.1%, polysorbate 80 0.3%, caprylic/capric acid 0.1% triglyceride is dissolved in water and emulsified uniformly.
  • the 10000g emulsified mixture is infiltrated with 100g/m2 carboxymethyl cellulose fiber 1m 2 and freeze-dried in vacuum at -50°C ⁇ -25°C to form freeze-dried ⁇ Film layer.
  • Comparative Example 5 Use the similar formula of Example 5 to make.
  • An ordinary skin lightening essence mask the formula is water (to 100%), niacinamide 3%, scutellaria root extract 1%, soluble glycoprotein 1%, polysorbate 80 1.5%, caprylic/capric triglyceride 2%, 0.5% phenoxyethanol, 0.2% methyl paraben, 0.1% polysorbate 80.
  • the membrane cloth is 30% seaweed fiber, and the packaging is multi-piece plastic box.
  • the ingredients When used, because the ingredients contain preservatives, it will cause a certain irritation to the epidermis, and it will sting after accidentally entering the eyes.
  • the tracking test results for the content of nicotinamide and scutellaria root extract showed that after the product was packaged, the dry towel of Example 5 and the facial mask of Comparative Example 5 were placed in the same cool storage for 1 year, and the nicotinamide in Example 1 and The content loss of Scutellaria baicalensis Root extract was less than 4%, the nicotinamide in the facial mask of Comparative Example 5 lost 24%, and the Scutellaria baicalensis Root extract 28%; there was a significant difference in the stability of the active substance.
  • a rapid skin moisture detector was used to detect the moisture content of the epidermis. After the dry towel in Example 1 was wiped 5 times (15s), the moisture content of the epidermis increased from the initial value of 26% to 49%; in Comparative Example 1, the facial mask was applied. After 15 seconds, the skin moisture content increased from the initial value of 26% to 30%, and after 5 minutes of application, the skin moisture content increased from the initial value of 28% to 45%. It can be seen that the essence dry towel can effectively improve skin hydration due to its rapid film formation on the skin surface.
  • a dry towel comprising a release layer, a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form.
  • the dry towel is in contact with 0.0001 ml/cm 2 of water, and the The freeze-dried film layer can be dissolved in 8 seconds, and the dissolution rate of the freeze-dried effective substance reaches more than 90% within 1 min.
  • the shape of the base fabric carrier layer is an eye mask type non-woven fabric, and the material is a blended fiber of bamboo fiber and tencel.
  • the shape and size of the release layer are the same as the base fabric carrier layer, and the material is pp.
  • the thickness of the dry film layer is 1 ⁇ m.
  • the freeze-dried film layer is composed of a freeze-dried functional substance and a freeze-dried skin feel agent, the freeze-dried functional substance is hesperidin, Canadian red maple extract, acetyl tetrapeptide-2, the freeze-dried skin feel agent It is polyglycerol-10 glyceride, fructan, and hydroxyethyl urea.
  • the dry towel is processed by the following method:
  • Step 1 Add hesperidin 1%, Canadian red maple extract 0.5%, acetyl tetrapeptide-2 0.001%, polyglycerol-10 glyceride 0.5%, fructan 0.5%, and hydroxyethyl urea 5% with water ( To 100%) dissolve, spray on the surface of the base cloth, freeze-dry under vacuum at -50°C ⁇ -25°C;
  • Step 2 Compound with the pp release layer to form the final product.
  • the dry towel in this embodiment is used as a skin care towel around the eyes.
  • the product When the product is assembled, it is sewn on the inner surface of the steam eye mask and is packaged as a single piece.
  • the steam eye mask When in use, the steam eye mask will generate 0.0001ml/cm 2 of water vapor.
  • the freeze-dried film layer After contact with the care towel on the inner surface, the freeze-dried film layer is dissolved and dissolved, peeled off from the carrier layer of the base cloth, and a film is formed on the epidermis around the eye. The result of skin care around the eyes.
  • the packaging structure of the dry towel in this embodiment is a sealed bag packaging.
  • Comparative Example 6 Use the similar formula of Example 6 to make.
  • a wet wipe for eye care comprising a release layer and a wet wipe.
  • the formula of the care solution in the wet wipe is water (to 100%), hesperidin 1%, Canadian red maple extract 0.5%, acetyl group Tetrapeptide-2 0.001%, polyglycerol-10 glyceride 0.5%, fructan 0.5%, hydroxyethyl urea 5%, 0.2% methyl paraben, 0.1% polysorbate 80.
  • the moisture content of the skin around the eyes increased from 27% to 50%, while the comparative example
  • the moisture content of the eye skin care wipes increased from 27% to 34% after 15 seconds of wet application around the eyes, and increased to 46% after 5 minutes of wet application.
  • a dry towel comprising a release layer, a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form.
  • the dry towel is in contact with 0.1 ml/cm 2 of water, and the The freeze-dried film layer can be dissolved in 9 seconds, and the dissolution rate of the freeze-dried functional substance reaches more than 90% within 1 min.
  • the shape of the base fabric carrier layer is a square non-woven fabric, the material is pure cotton, the shape and size of the release layer are the same as the base fabric carrier layer, the material is pe, and the thickness of the freeze-dried film layer is 85 ⁇ m .
  • the freeze-dried film layer includes a freeze-dried functional substance, a freeze-dried skin feel agent and a freeze-dried fiber
  • the freeze-dried functional substance is fatty acid amide alkyl betaine
  • the freeze-dried skin feel agent is oleyl alcohol, petrolatum, and polyglycerin -10-stearate
  • the freeze-dried fiber is water-soluble seaweed fiber.
  • the dry towel is processed by the following method:
  • Step 1 Disperse fatty acid amide alkyl betaine into oleyl alcohol with a dispersion ratio of 1:1;
  • Step 3 Coating on the surface of the base cloth, freeze-drying at -50°C ⁇ -20°C.
  • the dry wipes in this embodiment are used as eye makeup remover dry wipes.
  • the dry towel When in use, the dry towel is first contacted with water to emulsify, dissolve and dissolve the lyophilized film layer, and then when rubbing against the epidermis, the lyophilized film layer is peeled off from the base fabric carrier layer to form a film on the epidermis, After dissolving the eye makeup, continue to wipe and remove the makeup.
  • a dry towel comprising a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form, the dry towel is in contact with 0.05 ml/cm 2 of water, the freeze-dried film layer It can be dissolved within 4s, and the dissolution rate of the lyophilized product can reach more than 90% within 1 min.
  • the shape of the base fabric carrier layer is a circular non-woven fabric, and the material is a tencel and cupr ammonia blended non-woven fabric, and the thickness of the freeze-dried film layer is 10 ⁇ m.
  • the freeze-dried film layer only includes freeze-dried functional substances, and the freeze-dried functional substances are epidermal growth factor.
  • the dry towel is processed by the following method:
  • Step 1 Dissolve 6mg of epidermal growth factor with water (to 400ml), spray it on the surface of the blended base fabric of Tencel and cupra, and freeze-dry under vacuum at -50°C ⁇ -30°C;
  • Step 2 Pack the ingredients of the skin healing dressing dry towel.
  • the dry towel in this embodiment is used as a dressing dry towel. When in use, it can directly contact the wound exudate on the skin surface, or spray a small amount of sterile water to dissolve or dissolve the freeze-dried film layer, and then when rubbing with the epidermis, the freeze-dried film layer and the base cloth carrier layer Peeling, forming a film on the epidermis, playing a role in skin care and promoting healing.
  • the wound can be wiped twice, and the wound is isolated from the external environment, and the wound healing time is about 10 hours, while the liquid wound patch containing epidermal growth factor is used, and the wound healing time is about 24 hours.
  • a dry towel comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel is in contact with 0.005 ml/cm 2 of water, the freeze-dried film layer It can be dissolved within 4s, and the dissolution rate of the lyophilized product can reach more than 90% within 1 min.
  • the shape of the base fabric carrier layer is a square non-woven fabric, and the material is a blend of pure cotton and tencel, and the thickness of the freeze-dried film layer is 2 ⁇ m.
  • the freeze-dried film layer includes freeze-dried functional substances and freeze-dried fibers, the freeze-dried functional substances are salicylic acid and papain, and the freeze-dried fibers are collagen fibers.
  • the dry towel is processed by the following method:
  • Step 1 Dissolve 0.1% salicylic acid and 1% papain in water (to 100%), spray it on the surface of 28g/m2 collagen fiber at a ratio of 200-300g/m2, and freeze under vacuum at -50°C ⁇ -30°C dry;
  • Step 2 The freeze-dried film is combined with the blended base fabric of pure cotton and Tencel to form a dry cuticle softening towel.
  • the dry towel in this embodiment is used as a cuticle softening dry towel.
  • the content of the ingredients is adjusted as follows: 0.5% salicylic acid, 0.5% papain and water (to 100%) to dissolve, and the obtained 100ml solution is sprayed with 1m 2 of collagen fiber at 100g/m2 surface;
  • Salicylic acid or 0.5%, 0.5% papain was added water (100%) was dissolved, and the resulting solution was 100ml, sprayed in 2 0.4g / collagen 1m square meters of fiber surface; get the same effect to soften the skin dry towel.
  • Cuticle softening wet wipes (brand: Chunyu, commercially available): its formula contains water, methyl propylene glycol (irritant), 1,2 hexanediol (anticorrosive), PEG/PPG-17-6 copolymer, alcohol ( Irritant), birch juice, lactic acid (irritant), glycolic acid (irritant), dipropylene glycol (preservative), eggplant fruit extract, sodium hyaluronate, salicylic acid (irritant), licorice root extract, ethyl Hexanediol, grape fruit extract, apple extract, lemon fruit extract, bitter orange extract, citrus extract, Centella asiatica extract, tea extract, Chuanmu leaf extract, Calendula leaf extract , PEG-60 hydrogenated castor oil, sodium benzotriazolyl butyl phenol sulfonate (sunscreen agent), polyglycerol ether-26, buteth-3 (irritant), tributyl citrate (irritant), Tre
  • a dry towel comprising a double-layer release layer, a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form, the dry towel being in contact with 0.08 ml/cm 2 of water,
  • the freeze-dried film layer can be dissolved within 8 seconds, and the dissolution rate of the freeze-dried functional substance reaches more than 90% within 1 min.
  • the shape of the base fabric carrier layer is a square non-woven fabric, and the material is ordinary non-woven fabric.
  • the properties of the release layer are consistent with the base fabric carrier layer.
  • the two-layer materials are each bopp and aluminum foil.
  • the freeze-dried film layer The thickness is 150 ⁇ m.
  • the freeze-dried film layer comprises a freeze-dried functional substance, a freeze-dried skin feel agent and a freeze-dried fiber
  • the freeze-dried functional substance is ceramide, calamine, zinc oxide
  • the freeze-dried skin feel agent is propylene glycol, glycerin
  • the freeze-dried fiber is seaweed fiber.
  • the dry towel is processed by the following method:
  • Step 1 Dissolve ceramide 0.1%, calamine 2%, zinc oxide 1%, propylene glycol 2%, and glycerin 15% in water (to 100%), spray on the surface of the seaweed fiber, and freeze in vacuum at -50°C-25°C dry;
  • Step 2 The above freeze-dried film layer is compounded with the non-woven fabric base fabric
  • Step 3 Compound with the double-layer release layer to form the final product.
  • the dry towel in this embodiment is used as a dry towel for external rash care.
  • the exuded wound tissue fluid can promote the dissolution or dissolution of the freeze-dried film layer, and then when rubbing with the epidermis, the freeze-dried film layer is peeled from the base cloth carrier layer, It forms a film on the epidermis to eliminate itching and swelling, and play an adjuvant therapy role.
  • a dry towel comprising a release layer, a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form.
  • the dry towel is in contact with 0.03 ml/cm 2 of water, and the The lyophilized film can be dissolved in 6s.
  • the shape of the base fabric carrier layer is irregular, the material is non-woven fabric, the release layer has the same properties as the base fabric carrier layer, the material is pu, and the thickness of the freeze-dried film layer is 15 ⁇ m.
  • the freeze-dried film layer contains a freeze-dried skin feel agent, and the freeze-dried skin feel agent is xanthan gum and tremella polysaccharide.
  • the dry towel is processed by the following method:
  • Step 1 Dissolve 0.2% xanthan gum and 0.3% Tremella polysaccharide with water (to 100%), apply on the surface of the base cloth, and freeze-dry at -50°C-30°C;
  • Step 2 Compound with the release layer to form the final product.
  • the dry towel in this embodiment is used as a moisturizing essence dry towel.
  • the dry towel is first contacted with water to dissolve or dissolve the freeze-dried film layer, and then when rubbing against the epidermis, the freeze-dried film layer is peeled off from the base fabric carrier layer to form a film on the epidermis.
  • moisturizing and emollient The role of moisturizing and emollient.
  • the moisturizing essence dry wipes of this example are wiped 3 times, and the skin moisture content can reach 49% after 10 seconds.
  • Common commercially available wipes generally need to be wet for 10-15 minutes before the skin moisture content can reach 45%.
  • a dry towel comprising a release layer, a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form.
  • the dry towel is in contact with 0.0015 ml/cm 2 of water, and the The lyophilized film can be dissolved in 7 seconds.
  • the shape of the base fabric carrier layer is rectangular, the material is bamboo fiber, the shape of the release layer is consistent with the base fabric carrier layer, the material is PVC, and the thickness of the freeze-dried film layer is 25 ⁇ m.
  • the freeze-dried film layer is freeze-dried fiber, and the freeze-dried fiber is alginate fiber.
  • the dry towel is processed by the following method:
  • Step 1 Add the alginate fiber to 0.2% sodium citrate solution, freeze-dried at -50°C to -30°C, and composite with the base cloth;
  • Step 2 Compound with the release layer to form the final product.
  • the dry wipes in this embodiment are suitable for baby wet wipes.
  • first contact the dry towel with 0.0015ml/cm 2 of water.
  • the freeze-dried film layer can also be dissolved or dissolved within 7 seconds, and then when friction occurs with the epidermis, The freeze-dried film layer is peeled from the carrier layer of the base cloth to form a film on the epidermis to play a role of moisturizing and emollient.
  • a dry towel comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel is in contact with 0.02 ml/cm 2 of water, the freeze-dried film layer It can be dissolved within 5s.
  • the shape of the base fabric carrier layer is irregular, the material is non-woven fabric, and the thickness of the freeze-dried film layer is 2.5 ⁇ m.
  • the freeze-dried film layer comprises a freeze-dried skin feel agent and freeze-dried fiber, the freeze-dried skin feel agent is sugar isomers, octyl glycol and sodium polyacrylate, and the freeze-dried fiber is seaweed fiber.
  • the dry towel is processed by the following method:
  • Step 1 Dissolve carbohydrate isomer 1.5%, octylene glycol 5%, sodium polyacrylate 0.2% with water (to 100%), and apply 15-35g/m2 to 65g/m2 seaweed fiber The surface is freeze-dried at -50°C-30°C to form a freeze-dried film;
  • Step 2 The freeze-dried film and the carrier layer are compounded to form the final product.
  • the dry towel in this embodiment is used as a moisturizing essence dry towel.
  • the towel dry the water contact 0.02ml / cm 2 and the lyophilized film was dissolved within 5s or dissolution, and then wipe the skin, the lyophilized carrier base fabric layer delamination in the epidermis It forms a film on the top to play the role of moisturizing and emollient.
  • the moisturizing essence dry wipes of this example are wiped twice, and the skin moisture content can reach 50% after 15 seconds.
  • Common commercially available wipes generally require 10-15 minutes of wet dressing before the skin moisture content can reach 40%.
  • Step 1 Dissolve sugar isomer 0.8%, octyl glycol 0.1%, sodium polyacrylate 0.1% with water (to 100%), take 100ml, and apply the ratio on the surface of 0.2g/m2 seaweed fiber. Freeze drying at -50°C-30°C to form a lyophilized film;
  • step 1 Dissolve sugar isomer 0.8%, octyl glycol 0.1%, sodium polyacrylate 0.1% with water (to 100%), take 100ml, and apply the ratio on the surface of 1000g/m2 seaweed fiber. Freeze drying at -50°C-30°C to form a lyophilized film;
  • step 1 Dissolve sugar isomer 0.8%, octylene glycol 0.1%, sodium polyacrylate 0.1% with water (to 100%), take 10000ml, and apply the ratio on the surface of 0.2g/m2 seaweed fiber , Freeze dried at -50°C-30°C to form a lyophilized film;

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Abstract

A dry towel, a processing method therefor and an application thereof; the dry towel comprises a base towel carrier layer and a freeze-dried film layer that is attached to the base towel carrier layer in a freeze-dried form; the base towel carrier layer and the freeze-dried film layer contact 0.0001 ml/cm2-0.1 ml/cm2 of water, and the freeze-dried film layer can be dissolved or dissolved out. The freeze-dried film layer comprises a freeze-dried functional substance, or further comprises one or both among a freeze-dried skin sensation agent and freeze-dried fiber. When the dry towel contacts water, the freeze-dried film layer dissolves or dissolves out, and then when friction occurs with the epidermis, the freeze-dried film layer peels off from the base towel carrier layer and forms a film on the epidermis. The dry towel may be used as a skin care product, a makeup removing and cleansing product, a transdermal absorption external medicine patch or a wound dressing patch.

Description

一种干巾及其加工方法和应用Dry towel and its processing method and application 技术领域Technical field
本发明涉及贴敷用品技术领域,特别是涉及一种干巾及其加工方法和应用。The invention relates to the technical field of sticking products, in particular to a dry towel and its processing method and application.
背景技术Background technique
目前市面上的护肤面巾大都以湿巾形式为主,有效成分呈液体状态与面膜基布浸润,面膜中有效成分呈液体状态,如此需要加入添加剂以防止其氧化或滋生细菌,由于这些添加剂的存在,消费者使用时会出现各种不适,比如刺痛感、红肿、瘙痒或其他过敏现象。At present, most of the skin care facial towels on the market are mainly in the form of wet wipes. The active ingredients are in a liquid state and are infiltrated with the mask base cloth. The effective ingredients in the mask are in a liquid state. Additives are needed to prevent oxidation or growth of bacteria. Due to the existence of these additives , Consumers will experience various discomforts, such as tingling, redness, itching or other allergies when using it.
比如市售的Stridex水杨酸清洁祛痘、Medicube美帝秋芙乐、得洁柔收缩毛孔爽肤棉片、悦诗风吟Truecare积雪草修复保湿精华棉片、DERMATORY德玛多利低敏修复纱布贴、GRAYMELIN花汁保湿棉片、韩国丽得姿高效保湿水润棉片、PETITFEE/璞帝妃脸部补水棉片、NIGHTINGALE南丁格尔水光棉片等,以上这些产品中,有效成分大都为液体状态,存在有效成分不稳定,含有添加剂等问题,另外,使用时需要贴面使用或者反复擦拭,有效成分转移至皮肤表层时不成膜,挥发较快,溶出和透皮吸收速度慢。For example, the commercially available Stridex salicylic acid cleansing acne, Medicube, Dejie soft pore shrinking toning cotton sheet, Innisfree Truecare Centella asiatica repair moisturizing essence cotton sheet, DERMATORY DeMadori hypoallergenic repair gauze Paste, GRAYMELIN flower juice moisturizing cotton sheet, Korea Li Dezi high-efficiency moisturizing moisturizing cotton sheet, PETITFEE/Pu Difei facial moisturizing cotton sheet, NIGHTINGALE Nightingale water light cotton sheet, etc. Among the above products, most of the active ingredients are In liquid state, there are problems such as unstable active ingredients and containing additives. In addition, it needs to be used on the surface or repeatedly wiped during use. When the active ingredients are transferred to the skin surface, they will not form a film, volatilize quickly, and dissolve and absorb through the skin slowly.
市面上还有一些面膜产品的有效成分以冻干形式附着于膜布上,虽然减少甚至避免了多种添加剂的引入,但其使用形式仍然是贴面式,需要将面膜利用大量的水、精华液、护理液或其他功能液体浸湿后再使用,如果用功能液体浸湿,那仍然存在功能液体中有效成分不稳定和含有添加剂易产生刺激的问题,如果功能液体为水,则需要大量水浸泡,又存在携带不便的问题。There are also some facial mask products on the market whose active ingredients are attached to the membrane cloth in a freeze-dried form. Although the introduction of various additives is reduced or even avoided, the form of use is still a veneer type, which requires the use of a large amount of water and essence. Use liquid, care liquid or other functional liquids after being soaked. If the functional liquid is soaked, the active ingredients in the functional liquid are unstable and the additives are easily irritated. If the functional liquid is water, a lot of water is needed. Soaking, there is the problem of inconvenience to carry.
发明内容Summary of the invention
本发明的目的是针对现有技术中存在的干巾使用方式存在不便的问题,而提供一种干巾,该干巾遇水后,有效成分溶解或溶出,一擦即可在表皮成膜,使用方便,使用省时省力。The purpose of the present invention is to solve the problem of inconvenience in the use of dry towels in the prior art, and to provide a dry towel. After the dry towel meets with water, the active ingredients are dissolved or dissolved, and a film can be formed on the epidermis with one rub. Easy to use, save time and effort.
本发明的另一个目的是提供所述干巾的加工工艺,本加工工艺采用浸渍、喷涂后冻干,或熔融涂布后冻干的加工方式,工艺简单便于商业化推广应用。Another object of the present invention is to provide a processing technology of the dry towel. The processing technology adopts a processing method of dipping, spraying and then freeze-drying, or melt coating and then freeze-drying. The technology is simple and convenient for commercial promotion and application.
本发明的另一个目的是提供所述干巾的包装,可提供良好的密封环境,具有防潮的功能。Another object of the present invention is to provide a package of the dry towel, which can provide a good sealing environment and has a moisture-proof function.
本发明的另一个目的是提供所述干巾的应用,其可应用于护肤用品、卸妆清洁用品、透皮吸收外用药贴片或创面敷料贴片。Another object of the present invention is to provide the application of the dry towel, which can be applied to skin care products, makeup remover and cleansing products, transdermal absorption external medicine patches or wound dressing patches.
为实现本发明的目的所采用的技术方案是:The technical solutions adopted to achieve the purpose of the present invention are:
一种干巾,包括基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.0001ml/cm 2-0.1ml/cm 2的水接触,所述冻干膜层即可溶解或溶出。 A dry towel comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel being in contact with 0.0001ml/cm 2 -0.1ml/cm 2 of water, The freeze-dried film can be dissolved or dissolved out.
在上述技术方案中,溶解或溶出的时间为3-10s,冻干膜层既可以是分层形成基布载体层表面上的冻干层,也可以是部分或全部嵌入基布载体层内的冻干层。In the above technical scheme, the dissolution or dissolution time is 3-10s, and the freeze-dried film layer can be either layered to form a freeze-dried layer on the surface of the base fabric carrier layer, or partially or completely embedded in the base fabric carrier layer Freeze-dried layer.
护肤、药用活性成分通过特殊工艺融入冻干膜层进行成体冻干成型,具有优良的保护效果,且由于冻干后结构疏松、多孔的特点,使得冻干膜层,利用少量水,即可迅速坍塌结构、溶解溶出,并由于体温的蒸发作用,迅速在表皮脱水成膜,起到相应的护肤或药用敷料效果。The skin care and medicinal active ingredients are integrated into the freeze-dried film through a special process to form an adult freeze-dried, which has an excellent protective effect, and due to the loose and porous structure after freeze-drying, the freeze-dried film can be formed with a small amount of water. It quickly collapses the structure, dissolves and dissolves, and due to the evaporation of body temperature, it quickly dehydrates into a film on the epidermis, which has the corresponding skin care or medicinal dressing effect.
冻干膜层与基布载体层复合后,使冻干膜层具有良好的韧性,以防在生产过程中破损造成成本浪费,并保护在物流和货架期中的形态完整性。After the freeze-dried film layer is compounded with the base fabric carrier layer, the freeze-dried film layer has good toughness to prevent damage during the production process and cause cost waste, and protect the morphological integrity during logistics and shelf life.
在上述技术方案中,所述冻干膜层的厚度为0.1μm-300μm。In the above technical solution, the thickness of the freeze-dried film layer is 0.1 μm-300 μm.
在上述技术方案中,所述干巾还包括离型层。离型层起到进一步保护的作用,以保护冻干膜层的完整性,并提高卫生性。离型层位于基布载体层的一侧,其既可以位于冻干膜层的一侧,也可以位于背对冻干膜的一侧,同时离型层也可设置两层位于基布载体层的两侧。In the above technical solution, the dry towel further includes a release layer. The release layer plays a further protective role to protect the integrity of the freeze-dried film layer and improve hygiene. The release layer is located on one side of the base fabric carrier layer, which can be located on the side of the freeze-dried film layer or the side opposite to the freeze-dried film. At the same time, the release layer can also be provided with two layers on the base fabric carrier layer On both sides.
在上述技术方案中,所述基布载体层的形状为圆形、方形、多边形或不规则形,所述基布载体层可展开状态或压缩状态,所述基布载体层的材质为无纺布、脱脂棉、棉纤维、竹纤维、海藻纤维、天丝、铜氨、莫代尔纤维中的一种或多种混纺。In the above technical solution, the shape of the base fabric carrier layer is circular, square, polygonal or irregular, the base fabric carrier layer can be expanded or compressed, and the material of the base fabric carrier layer is non-woven One or more blends of cloth, absorbent cotton, cotton fiber, bamboo fiber, seaweed fiber, tencel, cupra, and modal fiber.
在上述技术方案中,所述离型层为pet、pe、pu、bopp、pvc、pp、铝箔中的一种或多种复合而成。所述离型层的形状和大小可与所述基布载体层的形状和大小相同,使用时先丢弃离型层,再将所述基布载体层和冻干膜层与水接触。In the above technical solution, the release layer is a composite of one or more of pet, pe, pu, bopp, pvc, pp, and aluminum foil. The shape and size of the release layer can be the same as the shape and size of the base fabric carrier layer. The release layer is discarded before use, and then the base fabric carrier layer and the freeze-dried film layer are in contact with water.
在上述技术方案中,所述冻干膜层包括冻干功效物、冻干肤感剂或冻干纤维中的一种或组合。冻干功效物为护肤、药用活性成分,所述冻干肤感剂加少量水即可溶胀溶解,必要时可进一步添加冻干纤维(如冻干胶原蛋白丝)进行成膜性固定。In the above technical solution, the freeze-dried film layer includes one or a combination of freeze-dried efficacy substances, freeze-dried skin feel agents, or freeze-dried fibers. The freeze-dried product is an active ingredient for skin care and medicine. The freeze-dried skin feel agent can be swelled and dissolved by adding a small amount of water. If necessary, freeze-dried fibers (such as freeze-dried collagen silk) can be further added for film-forming fixation.
在上述技术方案中,当所述冻干膜层包括冻干功效物、冻干肤感剂和冻干纤维时,其中,所述冻干功效物、冻干肤感剂和冻干纤维的质量比为(1-30):(0.1-50):(0.1-100);In the above technical solution, when the freeze-dried film layer includes freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers, the quality of the freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers The ratio is (1-30): (0.1-50): (0.1-100);
当所述冻干膜层包括冻干功效物和冻干肤感剂时,所述冻干功效物和冻干肤感剂的质量比为(1-30):(0.1-30);When the freeze-dried film layer includes a freeze-dried functional substance and a freeze-dried skin feel agent, the mass ratio of the freeze-dried functional substance and the freeze-dried skin feel agent is (1-30): (0.1-30);
当所述冻干膜层包括冻干功效物和和冻干纤维时,所述冻干功效物和冻干纤维的质量比为(1-100):(0.4-100);When the freeze-dried film layer includes freeze-dried functional substances and freeze-dried fibers, the mass ratio of the freeze-dried functional substances and freeze-dried fibers is (1-100): (0.4-100);
当所述冻干膜层包括冻干肤感剂和冻干纤维时,所述冻干肤感剂和冻干纤维的质量比为(1-100):(0.2-1000)。When the freeze-dried film layer includes the freeze-dried skin feel agent and the freeze-dried fiber, the mass ratio of the freeze-dried skin feel agent and the freeze-dried fiber is (1-100): (0.2-1000).
在上述技术方案中,所述冻干功效物选自西药成分、中药成分、天然提取物、生物活性成分、皮肤护理有益成分中的一种或组合,所述冻干肤感剂选自蛋白类、多糖及其盐类、高分子聚合物类、多元醇类、天然及合成油脂类、表面活性剂类中的一种或组合,所述冻干纤维为胶原蛋白纤维、壳聚糖纤维、海藻盐纤维、藻壳共混纤维、羧甲基纤维素纤维中的一种或组合。In the above technical solution, the freeze-dried effect is selected from one or a combination of western medicine ingredients, traditional Chinese medicine ingredients, natural extracts, biologically active ingredients, and skin care beneficial ingredients, and the freeze-dried skin feel agent is selected from protein , Polysaccharides and their salts, high molecular polymers, polyols, natural and synthetic oils and fats, or a combination of surfactants, the freeze-dried fiber is collagen fiber, chitosan fiber, seaweed One or a combination of salt fiber, algae shell blend fiber and carboxymethyl cellulose fiber.
所述冻干功效物中的西药成分为酮洛芬、布洛芬、萘甲唑啉、双氯芬酸二乙胺、酮康唑、氢化可的松、咪康唑氯倍他索、曲咪新、间苯二酚,所述中药成分为冰片、薄荷、樟脑、甘草、黄芩、姜黄、大黄、硫磺、苦参、蛇床子、黄连、黄柏、炉甘石、氧化锌,所述天然提取物为橙皮苷提取物、加拿大红枫提取物、黄芩根提取物、无患子提取物、脂肪酸酰胺烷基 甜菜碱、积雪草提取物、针叶樱桃提取物、芍药根提取物、莲花提取物、雪莲提取物、人参根提取物、黄瓜果提取、芦荟叶提取物、马齿苋提取物、甘牛至叶提取物、接骨木提取物、玫瑰提取物、海藻提取物、松露提取物、冬虫夏草提取物、西红花提取物、银耳提取物、当归提取物、五味子提取物、母菊花提取物、山茶花提取物、白术提取物、三七提取物、姜根提取物、白芨提取物、白鲜皮提取物、薰衣草提取物、白蒺藜提取物或霍霍巴叶提取物,所述生物活性成分为表皮生长因子、寡肽-1、芽孢杆菌发酵产物、乙酰基四肽-2、乙酰基六肽-1、棕榈酰三肽、铜肽、肌肽、氨基丁酸或木瓜蛋白酶,所述皮肤护理成分为橙皮苷、牛奶蛋白、乙酰基六肽-1、芽孢杆菌发酵产物、月桂酰谷氨酸钠、乙酰化透明质酸钠、神经酰胺、椰油基甜菜碱、水杨酸、乳酸、羟基乙酸、谷胱甘肽、SOD、辅酶Q10、烟酰胺、生育酚及衍生物、视黄醇及衍生物、抗坏血酸及衍生物、海藻糖、糖类同分异构体、角鲨烷、乳木果油、阿魏酸、胶原蛋白、甘油葡糖苷、咖啡因、四氢甲基嘧啶羧酸、红没药醇、水飞蓟素、白藜芦醇、植物甾醇或虾青素;The western medicine components in the freeze-dried effect are ketoprofen, ibuprofen, naphazoline, diclofenac diethylamine, ketoconazole, hydrocortisone, miconazole, clobetasol, trichomidine, Resorcinol, the traditional Chinese medicine ingredients are borneol, mint, camphor, licorice, scutellaria, turmeric, rhubarb, sulfur, sophora flavescens, cranberry, coptis, cork, calamine, zinc oxide, and the natural extract is orange Cortin extract, Canadian red maple extract, Scutellaria baicalensis root extract, Sapindus extract, fatty acid amide alkyl betaine, Centella asiatica extract, acerola cherry extract, peony root extract, lotus extract, Snow lotus extract, ginseng root extract, cucumber fruit extract, aloe leaf extract, portulaca extract, sweet oregano leaf extract, elderberry extract, rose extract, seaweed extract, truffle extract, cordyceps sinensis Extract, Saffron Extract, Tremella Extract, Angelica Extract, Schisandra Extract, Matricaria Flower Extract, Camellia Flower Extract, Atractylodes Rhizome Extract, Panax Notoginseng Extract, Ginger Root Extract, Bletilla striata Extract, White Fresh Bark extract, lavender extract, Tribulus terrestris extract or Jojoba leaf extract, the biologically active ingredients are epidermal growth factor, oligopeptide-1, Bacillus fermentation product, acetyl tetrapeptide-2, acetyl hexapeptide -1. Palmitoyl tripeptide, copper peptide, carnosine, aminobutyric acid or papain, the skin care ingredients are hesperidin, milk protein, acetyl hexapeptide-1, bacillus fermentation product, lauroyl glutamic acid Sodium, sodium acetylated hyaluronate, ceramide, cocobetaine, salicylic acid, lactic acid, glycolic acid, glutathione, SOD, coenzyme Q10, nicotinamide, tocopherol and derivatives, retinol and Derivatives, ascorbic acid and derivatives, trehalose, carbohydrate isomers, squalane, shea butter, ferulic acid, collagen, glycerol glucoside, caffeine, tetrahydromethylpyrimidine carboxylic acid, Bisabolol, silymarin, resveratrol, phytosterol or astaxanthin;
所述冻干肤感剂中的蛋白类为可溶性糖蛋白、胶原蛋白或水解明胶,所述多糖为果聚糖、黄原胶、透明质酸钠、聚谷氨酸、糖类同分异构体、银耳多糖或海藻糖,所述多元醇为丙二醇、甘油、丁二醇或辛甘醇,所述天然及合成油脂类为矿脂、油醇,辛酸/癸酸甘油三酯或氢化棕榈油,所述高分子聚合物类为聚丙烯酸钠或卡波姆,所述表面活性剂为聚甘油-10甘油酯、聚甘油-10-硬脂酸酯、聚山梨醇酯80、椰油基甜菜碱、月桂酰谷氨酸钠或脂肪酸酰胺烷基甜菜碱。The protein in the freeze-dried skin feel agent is soluble glycoprotein, collagen or hydrolyzed gelatin, and the polysaccharide is fructan, xanthan gum, sodium hyaluronate, polyglutamic acid, and carbohydrate isomers Body, tremella polysaccharide or trehalose, the polyol is propylene glycol, glycerin, butylene glycol or caprylyl, the natural and synthetic oils are petrolatum, oleyl alcohol, caprylic/capric triglyceride or hydrogenated palm oil , The high molecular polymer is sodium polyacrylate or carbomer, and the surfactant is polyglycerol-10 glyceride, polyglycerol-10-stearate, polysorbate 80, coco-beet Alkali, sodium lauroyl glutamate or fatty acid amide alkyl betaine.
在上述技术方案中,所述干巾通过以下方法加工:In the above technical solution, the dry towel is processed by the following method:
步骤1:将冻干功效物溶解或分散于冻干肤感剂中;Step 1: Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent;
步骤2:将冻干功效物与冻干肤感剂的混合物加温熔融至具有流动性;Step 2: The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
步骤3:涂布于基布表面,-50℃~-30℃冷冻干燥;Step 3: Coat on the surface of the base cloth, freeze-dry at -50℃~-30℃;
或者通过以下方法加工:Or process by the following methods:
步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒在冻干纤维表面或与冻干纤维相互浸润,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
步骤2:冻干膜与基布复合;Step 2: The freeze-dried film is combined with the base fabric;
或者通过以下方法加工:Or process by the following methods:
步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒于基布表面,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the base fabric, and freeze-dry at -50°C to -30°C;
步骤2:与离型层复合形成终产品。Step 2: Compound with the release layer to form the final product.
或者通过以下方法加工:Or process by the following methods:
步骤1:将冻干纤维加水或水溶液,-50℃~-30℃冷冻干燥后,与基布进行混纺复合;Step 1: Add water or aqueous solution to the freeze-dried fiber, freeze-dried at -50°C to -30°C, and blend and compound with the base fabric;
步骤2:与离型层复合形成终产品。Step 2: Compound with the release layer to form the final product.
在上述技术方案中,所述干巾与水接触,冻干膜层溶解或溶出,然后在与表皮发生接触或摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜。In the above technical solution, when the dry towel is in contact with water, the freeze-dried film layer is dissolved or dissolved, and then when contact or friction occurs with the epidermis, the freeze-dried film layer is peeled off from the base fabric carrier layer, and a film is formed on the epidermis .
本发明的另一方面,还包括所述干巾作为护肤用品、卸妆清洁用品、透皮吸收外用药贴片或创面敷料贴片的应用。使用者通过擦拭后,溶解或溶出的冻干功效物残留在皮肤上作为精华护肤干巾使用,也可通过擦拭时溶解皮肤表面彩妆、污渍等作为卸妆清洁干巾使用,比常规卸妆水更温和不刺眼。可通过擦拭后将溶解或溶出的冻干功效物残留在皮肤上,进行透皮吸收做外用药使用,避免瓶装的在开瓶后污染,可通过擦拭后将将溶解或溶出的冻干功效物残留在皮肤创面、隔离创面与外界环境作为敷料使用,作为液体创口贴使用,避免普通液体敷料开封后污染。In another aspect of the present invention, it also includes the application of the dry towel as a skin care product, a make-up remover cleaning product, a transdermal absorption external medication patch or a wound dressing patch. After the user wipes, the dissolved or eluted freeze-dried product remains on the skin as an essential skin care dry towel. It can also be used as a makeup remover and cleansing towel by dissolving makeup and stains on the skin surface during wiping, which is milder than conventional makeup remover. Not glaring. After wiping, the dissolved or eluted lyophilized product can be left on the skin for transdermal absorption and used as an external medicine to avoid contamination of the bottled after opening. The lyophilized product can be dissolved or dissolved after wiping. It is used as a dressing that remains on the skin wound and isolates the wound from the external environment, and used as a liquid wound dressing to avoid contamination of ordinary liquid dressings after opening.
本发明的另一方面,还包括所述干巾的包装。可以选自单次独立包装和多次集合包装中的一种;所述单次独立包装可以为具有隔潮、密封性能的包装,如袋装、盒装、泡罩包装、瓶装中的一种,优选铝塑泡罩装、硬铝小盒装、胶囊咖啡装、玻璃包装、金属包装中的一种;所述多次集合包装可以为具有隔潮、密封性能的包装,如袋装、盒装、泡罩包装、瓶装中的一种或组合,优选铝塑泡罩装、硬铝小盒装、胶囊咖啡装、玻璃包装、金属包装、塑料瓶、塑料盒、铝塑袋中的一种或组合。所述“多次集合包装”可以是多个干巾叠加或混合放置后封装到一个外包装里,也可以是单个或多个封装成一个子包装,多个子包装再封装到一个外包装里。所述“个”指的是独立的个体,根据干巾基布载体层的形状可以是片状、卷曲状或压缩状等形态。In another aspect of the present invention, it also includes the packaging of the dry towel. It can be selected from one of single independent packaging and multiple collective packaging; the single independent packaging can be a packaging with moisture barrier and sealing properties, such as one of bag, box, blister, and bottle , Preferably one of aluminum-plastic blister pack, hard aluminum small box, capsule coffee pack, glass packaging, and metal packaging; the multiple assembly packaging may be a packaging with moisture barrier and sealing properties, such as bag or box One or a combination of packaging, blister packaging, and bottle packaging, preferably one of aluminum-plastic blister packaging, hard aluminum small box, capsule coffee packaging, glass packaging, metal packaging, plastic bottle, plastic box, aluminum-plastic bag Or combination. The "multiple assembly packaging" can be multiple dry towels stacked or mixed and packaged in one outer package, or single or multiple packages are packaged into one sub package, and multiple sub packages are packaged in one outer package. The "piece" refers to an independent individual, which can be in the form of a sheet, a crimp, or a compressed form according to the shape of the carrier layer of the dry towel base fabric.
本发明的另一方面,还涉及以冻干形式形成在基布载体层上的冻干膜层,所述冻干膜层包括冻干功效物和/或冻干肤感剂和/或冻干纤维组成分,其中,所述冻干功效物选自西药成分、中药成分、天然提取物、生物活性成分、皮肤护理有益成分中的一种或组合,所述冻干肤感剂选自蛋白类、多糖及其盐类、高分子聚合物类、多元醇类、天然及合成油脂类、表面活性剂类中的一种或组合,所述冻干纤维为胶原蛋白纤维、壳聚糖纤维、海藻盐纤维、藻壳共混纤维、羧甲基纤维素纤维中的一种或组合。In another aspect of the present invention, it also relates to a freeze-dried film layer formed on a base cloth carrier layer in a freeze-dried form, the freeze-dried film layer comprising a freeze-dried functional substance and/or a freeze-dried skin feel agent and/or a freeze-dried Fiber component, wherein the freeze-dried effect is selected from one or a combination of western medicine ingredients, traditional Chinese medicine ingredients, natural extracts, biologically active ingredients, and skin care beneficial ingredients, and the freeze-dried skin feel agent is selected from protein , Polysaccharides and their salts, high molecular polymers, polyols, natural and synthetic oils and fats, or a combination of surfactants, the freeze-dried fiber is collagen fiber, chitosan fiber, seaweed One or a combination of salt fiber, algae shell blend fiber and carboxymethyl cellulose fiber.
在上述技术方案中,当所述冻干膜层包括冻干功效物、冻干肤感剂和冻干纤维时,其中,所述冻干功效物、冻干肤感剂和冻干纤维的质量比为(1-30):(0.1-50):(0.1-100);In the above technical solution, when the freeze-dried film layer includes freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers, the quality of the freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers The ratio is (1-30): (0.1-50): (0.1-100);
当所述冻干膜层包括冻干功效物和冻干肤感剂时,所述冻干功效物和冻干肤感剂的质量比为(1-30):(0.1-30);When the freeze-dried film layer includes a freeze-dried functional substance and a freeze-dried skin feel agent, the mass ratio of the freeze-dried functional substance and the freeze-dried skin feel agent is (1-30): (0.1-30);
当所述冻干膜层包括冻干功效物和和冻干纤维时,所述冻干功效物和冻干纤维的质量比为(1-100):(0.4-100);When the freeze-dried film layer includes freeze-dried functional substances and freeze-dried fibers, the mass ratio of the freeze-dried functional substances and freeze-dried fibers is (1-100): (0.4-100);
当所述冻干膜层包括冻干肤感剂和冻干纤维时,所述冻干肤感剂和冻干纤维的质量比为(1-100):(0.2-1000)When the freeze-dried film layer includes freeze-dried skin feel agent and freeze-dried fiber, the mass ratio of the freeze-dried skin feel agent and freeze-dried fiber is (1-100): (0.2-1000)
在上述技术方案中,所述冻干功效物中的西药成分为酮洛芬、布洛芬、萘甲唑啉、双氯芬酸二乙胺、酮康唑、氢化可的松、咪康唑氯倍他索、曲咪新、间苯二酚,所述中药成分为冰片、薄荷、樟脑、甘草、黄芩、姜黄、大黄、硫磺、苦参、蛇床子、黄连、黄柏、炉甘石、氧化锌,所述天然提取物为橙皮苷提取物、加拿大红枫提取物、黄芩根提取物、无患子提取物、脂肪酸酰胺烷基甜菜碱、积雪草提取物、针叶樱桃提取物、芍药根提取物、莲花提取物、 雪莲提取物、人参根提取物、黄瓜果提取、芦荟叶提取物、马齿苋提取物、甘牛至叶提取物、接骨木提取物、玫瑰提取物、海藻提取物、松露提取物、冬虫夏草提取物、西红花提取物、银耳提取物、当归提取物、五味子提取物、母菊花提取物、山茶花提取物、白术提取物、三七提取物、姜根提取物、白芨提取物、白鲜皮提取物、薰衣草提取物、白蒺藜提取物或霍霍巴叶提取物,所述生物活性成分为表皮生长因子、寡肽-1、芽孢杆菌发酵产物、乙酰基四肽-2、乙酰基六肽-1、棕榈酰三肽、铜肽、肌肽、氨基丁酸或木瓜蛋白酶,所述皮肤护理成分为橙皮苷、牛奶蛋白、乙酰基六肽-1、芽孢杆菌发酵产物、月桂酰谷氨酸钠、乙酰化透明质酸钠、神经酰胺、椰油基甜菜碱、水杨酸、乳酸、羟基乙酸、谷胱甘肽、SOD、辅酶Q10、烟酰胺、生育酚及衍生物、视黄醇及衍生物、抗坏血酸及衍生物、海藻糖、糖类同分异构体、角鲨烷、乳木果油、阿魏酸、胶原蛋白、甘油葡糖苷、咖啡因、四氢甲基嘧啶羧酸、红没药醇、水飞蓟素、白藜芦醇、植物甾醇或虾青素;In the above technical solution, the western medicine components in the freeze-dried product are ketoprofen, ibuprofen, naphazoline, diclofenac diethylamine, ketoconazole, hydrocortisone, miconazole clobeta The traditional Chinese medicine ingredients are borneol, menthol, camphor, licorice, scutellaria, turmeric, rhubarb, sulfur, sophora flavescens, cranberry, coptis, cork, calamine, zinc oxide, The natural extracts are hesperidin extract, Canadian red maple extract, Scutellaria baicalensis root extract, Sapindus extract, fatty acid amide alkyl betaine, Centella asiatica extract, Acerola cherry extract, Paeonia lactiflora root extract Extracts, lotus extract, yacon extract, ginseng root extract, cucumber fruit extract, aloe leaf extract, portulaca extract, sweet oregano leaf extract, elderberry extract, rose extract, seaweed extract , Truffle Extract, Cordyceps Extract, Saffron Extract, Tremella Extract, Angelica Extract, Schisandra Extract, Matricaria Flower Extract, Camellia Flower Extract, Atractylodes Rhizome Extract, Panax Notoginseng Extract, Ginger Root Extract, Bletilla striata extract, white fresh bark extract, lavender extract, Tribulus terrestris extract or jojoba leaf extract, the biologically active ingredients are epidermal growth factor, oligopeptide-1, bacillus fermentation product, acetyl tetrapeptide- 2. Acetyl hexapeptide-1, palmitoyl tripeptide, copper peptide, carnosine, aminobutyric acid or papain, the skin care ingredients are hesperidin, milk protein, acetyl hexapeptide-1, Bacillus fermentation product , Sodium lauroyl glutamate, sodium acetylated hyaluronate, ceramide, coco betaine, salicylic acid, lactic acid, glycolic acid, glutathione, SOD, coenzyme Q10, nicotinamide, tocopherol and derivatives Substances, retinol and derivatives, ascorbic acid and derivatives, trehalose, carbohydrate isomers, squalane, shea butter, ferulic acid, collagen, glycerol glucoside, caffeine, tetrahydro Methyl pyrimidine carboxylic acid, bisabolol, silymarin, resveratrol, phytosterol or astaxanthin;
所述冻干肤感剂中的蛋白类为可溶性糖蛋白、胶原蛋白或水解明胶,所述多糖为果聚糖、黄原胶、透明质酸钠、聚谷氨酸、糖类同分异构体、银耳多糖或海藻糖,所述多元醇为丙二醇、甘油、丁二醇或辛甘醇,所述天然及合成油脂类为矿脂、油醇,辛酸/癸酸甘油三酯或氢化棕榈油,所述高分子聚合物类为聚丙烯酸钠或卡波姆,所述表面活性剂为聚甘油-10甘油酯、聚甘油-10-硬脂酸酯、聚山梨醇酯80、椰油基甜菜碱、月桂酰谷氨酸钠或脂肪酸酰胺烷基甜菜碱。The protein in the freeze-dried skin feel agent is soluble glycoprotein, collagen or hydrolyzed gelatin, and the polysaccharide is fructan, xanthan gum, sodium hyaluronate, polyglutamic acid, and carbohydrate isomers Body, tremella polysaccharide or trehalose, the polyol is propylene glycol, glycerin, butylene glycol or caprylyl, the natural and synthetic oils are petrolatum, oleyl alcohol, caprylic/capric triglyceride or hydrogenated palm oil , The high molecular polymer is sodium polyacrylate or carbomer, and the surfactant is polyglycerol-10 glyceride, polyglycerol-10-stearate, polysorbate 80, coco-beet Alkali, sodium lauroyl glutamate or fatty acid amide alkyl betaine.
在上述技术方案中,所述冻干膜层通过以下步骤制备:In the above technical solution, the freeze-dried film layer is prepared by the following steps:
步骤1:将冻干功效物溶解或分散于冻干肤感剂中;Step 1: Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent;
步骤2:将冻干功效物与冻干肤感剂的混合物加温熔融至具有流动性;Step 2: The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
步骤3:-50℃~-30℃冷冻干燥;Step 3: Freeze drying at -50℃~-30℃;
或者通过以下方法加工:Or process by the following methods:
步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒在冻干纤维表面或与冻干纤维相互浸润,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
或者通过以下方法加工:Or process by the following methods:
步骤1:将冻干功效物溶解或分散于冻干肤感剂中;Step 1: Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent;
步骤2:将冻干功效物与冻干肤感剂的混合物加温熔融至具有流动性;Step 2: The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
步骤3:将上述混合物喷洒在冻干纤维表面或与冻干纤维相互浸润,-50℃~-30℃冷冻干燥;Step 3: Spray the above mixture on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
或者通过以下方法加工:Or process by the following methods:
步骤1:将冻干纤维加水或水溶液,-50℃~-30℃冷冻干燥。Step 1: Add water or aqueous solution to the freeze-dried fiber, freeze-dry it at -50°C to -30°C.
本发明的另一方面,包括一种干巾的加工方法,包括以下步骤:Another aspect of the present invention includes a method for processing dry towels, including the following steps:
步骤1:将冻干功效物溶解或分散于冻干肤感剂中;Step 1: Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent;
步骤2:将冻干功效物与冻干肤感剂的混合物加温熔融至具有流动性;Step 2: The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
步骤3:涂布于基布表面,-50℃~-30℃冷冻干燥;Step 3: Coat on the surface of the base cloth, freeze-dry at -50℃~-30℃;
或者通过以下方法加工:Or process by the following methods:
步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒在冻干纤维表面或与冻干纤维相互浸润,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
步骤2:冻干膜与基布复合;Step 2: The freeze-dried film is combined with the base fabric;
或者通过以下方法加工:Or process by the following methods:
步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒于基布表面,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the base fabric, and freeze-dry at -50°C to -30°C;
步骤2:与离型层复合形成终产品;Step 2: Compound with the release layer to form the final product;
或者通过以下方法加工:Or process by the following methods:
步骤1:将冻干纤维加水或水溶液,-50℃~-30℃冷冻干燥后,与基布进行混纺复合;Step 1: Add water or aqueous solution to the freeze-dried fiber, freeze-dried at -50°C to -30°C, and blend and compound with the base fabric;
步骤2:与离型层复合形成终产品。Step 2: Compound with the release layer to form the final product.
在上述技术方案中,所述冻干膜层包括冻干功效物和/或冻干肤感剂和/或冻干纤维组成分,其中,所述冻干功效物选自西药成分、中药成分、天然提取物、生物活性成分、皮肤护理有益成分中的一种或组合,所述冻干肤感剂选自蛋白类、多糖及其盐类、高分子聚合物类、多元醇类、天然及合成油脂类、表面活性剂类中的一种或组合,所述冻干纤维为胶原蛋白纤维、壳聚糖纤维、海藻盐纤维、藻壳共混纤维、羧甲基纤维素纤维中的一种或组合。In the above technical solution, the freeze-dried film layer includes freeze-dried functional substances and/or freeze-dried skin feel agents and/or freeze-dried fiber components, wherein the freeze-dried functional substances are selected from western medicine ingredients, traditional Chinese medicine ingredients, One or a combination of natural extracts, biologically active ingredients, skin care beneficial ingredients, the freeze-dried skin feel agent is selected from the group consisting of proteins, polysaccharides and their salts, high molecular polymers, polyols, natural and synthetic One or a combination of oils and surfactants, the freeze-dried fiber is one of collagen fiber, chitosan fiber, seaweed salt fiber, algae shell blend fiber, carboxymethyl cellulose fiber or combination.
在上述技术方案中,所述冻干功效物中的西药成分为酮洛芬、布洛芬、萘甲唑啉、双氯芬酸二乙胺、酮康唑、氢化可的松、咪康唑氯倍他索、曲咪新、间苯二酚,所述中药成分为冰片、薄荷、樟脑、甘草、黄芩、姜黄、大黄、硫磺、苦参、蛇床子、黄连、黄柏、炉甘石、氧化锌,所述天然提取物为橙皮苷提取物、加拿大红枫提取物、黄芩根提取物、无患子提取物、脂肪酸酰胺烷基甜菜碱、积雪草提取物、针叶樱桃提取物、芍药根提取物、莲花提取物、雪莲提取物、人参根提取物、黄瓜果提取、芦荟叶提取物、马齿苋提取物、甘牛至叶提取物、接骨木提取物、玫瑰提取物、海藻提取物、松露提取物、冬虫夏草提取物、西红花提取物、银耳提取物、当归提取物、五味子提取物、母菊花提取物、山茶花提取物、白术提取物、三七提取物、姜根提取物、白芨提取物、白鲜皮提取物、薰衣草提取物、白蒺藜提取物或霍霍巴叶提取物,所述生物活性成分为表皮生长因子、寡肽-1、芽孢杆菌发酵产物、乙酰基四肽-2、乙酰基六肽-1、棕榈酰三肽、铜肽、肌肽、氨基丁酸或木瓜蛋白酶,所述皮肤护理成分为橙皮苷、牛奶蛋白、乙酰基六肽-1、芽孢杆菌发酵产物、月桂酰谷氨酸钠、乙酰化透明质酸钠、神经酰胺、椰油基甜菜碱、水杨酸、乳酸、羟基乙酸、谷胱甘肽、SOD、辅酶Q10、烟酰胺、生育酚及衍生物、视黄醇及衍生物、抗坏血酸及衍生物、海藻糖、糖类同分异构体、角鲨烷、乳木果油、阿魏酸、胶原蛋白、甘油葡糖苷、咖啡因、四氢甲基嘧啶羧酸、红没药醇、水飞蓟素、白藜芦醇、植物甾醇或虾青素;In the above technical solution, the western medicine components in the freeze-dried product are ketoprofen, ibuprofen, naphazoline, diclofenac diethylamine, ketoconazole, hydrocortisone, miconazole clobeta The traditional Chinese medicine ingredients are borneol, menthol, camphor, licorice, scutellaria, turmeric, rhubarb, sulfur, sophora flavescens, cranberry, coptis, cork, calamine, zinc oxide, The natural extracts are hesperidin extract, Canadian red maple extract, Scutellaria baicalensis root extract, Sapindus extract, fatty acid amide alkyl betaine, Centella asiatica extract, Acerola cherry extract, Paeonia lactiflora root extract Extract, lotus extract, snow lotus extract, ginseng root extract, cucumber fruit extract, aloe leaf extract, portulaca extract, sweet oregano leaf extract, elderberry extract, rose extract, seaweed extract , Truffle Extract, Cordyceps Extract, Saffron Extract, Tremella Extract, Angelica Extract, Schisandra Extract, Matricaria Flower Extract, Camellia Flower Extract, Atractylodes Rhizome Extract, Panax Notoginseng Extract, Ginger Root Extract, Bletilla striata extract, white fresh bark extract, lavender extract, Tribulus terrestris extract or jojoba leaf extract, the biologically active ingredients are epidermal growth factor, oligopeptide-1, bacillus fermentation product, acetyl tetrapeptide- 2. Acetyl hexapeptide-1, palmitoyl tripeptide, copper peptide, carnosine, aminobutyric acid or papain, the skin care ingredients are hesperidin, milk protein, acetyl hexapeptide-1, Bacillus fermentation product , Sodium lauroyl glutamate, sodium acetylated hyaluronate, ceramide, coco betaine, salicylic acid, lactic acid, glycolic acid, glutathione, SOD, coenzyme Q10, nicotinamide, tocopherol and derivatives Substances, retinol and derivatives, ascorbic acid and derivatives, trehalose, carbohydrate isomers, squalane, shea butter, ferulic acid, collagen, glycerol glucoside, caffeine, tetrahydro Methyl pyrimidine carboxylic acid, bisabolol, silymarin, resveratrol, phytosterol or astaxanthin;
所述冻干肤感剂中的蛋白类为可溶性糖蛋白、胶原蛋白或水解明胶,所述多糖为果聚糖、黄原胶、透明质酸钠、聚谷氨酸、糖类同分异构体、银耳多糖或海藻糖,所述多元醇为丙二醇、甘油、丁二醇或辛甘醇,所述天然及合成油脂类为矿脂、油醇,辛酸/癸酸甘油三酯或 氢化棕榈油,所述高分子聚合物类为聚丙烯酸钠或卡波姆,所述表面活性剂为聚甘油-10甘油酯、聚甘油-10-硬脂酸酯、聚山梨醇酯80、椰油基甜菜碱、月桂酰谷氨酸钠或脂肪酸酰胺烷基甜菜碱。The protein in the freeze-dried skin feel agent is soluble glycoprotein, collagen or hydrolyzed gelatin, and the polysaccharide is fructan, xanthan gum, sodium hyaluronate, polyglutamic acid, and carbohydrate isomers Body, tremella polysaccharide or trehalose, the polyol is propylene glycol, glycerin, butylene glycol or caprylyl, the natural and synthetic oils are petrolatum, oleyl alcohol, caprylic/capric triglyceride or hydrogenated palm oil , The high molecular polymer is sodium polyacrylate or carbomer, and the surfactant is polyglycerol-10 glyceride, polyglycerol-10-stearate, polysorbate 80, coco-beet Alkali, sodium lauroyl glutamate or fatty acid amide alkyl betaine.
与现有技术相比,本发明的有益效果是:Compared with the prior art, the beneficial effects of the present invention are:
1.本发明的干巾中有效成分以冻干形式附着于基布载体层上,该干巾在存储运输过程中不会接触到水分,如此,本干巾中不添加防腐剂和抗菌剂,使用安全系数高。1. The active ingredients in the dry towel of the present invention are attached to the carrier layer of the base cloth in a freeze-dried form, and the dry towel will not be exposed to moisture during storage and transportation. Therefore, the dry towel does not add preservatives and antibacterial agents. The safety factor is high.
2.本发明的干巾中有效成分以冻干形式附着于基布载体层上,有效保持热敏性或易不稳定成分的活性保持,提高使用效果。2. The active ingredients in the dry towel of the present invention are attached to the carrier layer of the base cloth in a freeze-dried form, which effectively maintains the heat sensitivity or the activity of the easily unstable ingredients and improves the use effect.
3.由于冻干膜层具有“多孔”成分结构,从而使一些正常的增稠剂,本来需要溶胀溶解,因为多孔,极强的扩大和水的接触面积和效率,使其短时间、少量水就可以起到效果。本干巾的冻干膜层可利用少量(0.0001ml/cm 2-0.1ml/cm 2)的水溶解,如此可缩小干巾的包装容积,并适应在少水情况下的特殊应用。相比于传统干膜需要加入十几毫升或几十毫升的水而言,包装容积也需要与需水量适配,本干巾需要的水量少,包装也可相应缩小。由少量的水即可促进有效成分溶解或溶出达到效果,所以损伤小更安全,携带使用更方便,溶出和透皮吸收更强。 3. Because the freeze-dried film layer has a "porous" component structure, some normal thickeners originally need to be swollen and dissolved. Because of the porousness, the extremely strong expansion and water contact area and efficiency make it a short time and a small amount of water. It can be effective. The freeze-dried film layer of the dry towel can be dissolved in a small amount (0.0001ml/cm 2 -0.1ml/cm 2 ) of water, so that the packaging volume of the dry towel can be reduced, and it is suitable for special applications under the condition of less water. Compared with the traditional dry film that needs to add more than ten milliliters or tens of milliliters of water, the packaging volume also needs to be adapted to the water demand. The dry towel requires less water and the packaging can be reduced accordingly. A small amount of water can promote the dissolution or dissolution of the active ingredients to achieve the effect, so the damage is less and safer, it is more convenient to carry and use, and the dissolution and transdermal absorption are stronger.
4.冻干功效物、冻干肤感剂和冻干纤维与基布载体层的结合力不够强,经过选择酮洛芬、黄芩根提取物、表皮生长因子、牛奶蛋白等冻干功效物,可溶性糖蛋白、果聚糖、丙二醇、氢化棕榈油、聚谷氨酸钠等冻干肤感剂,胶原蛋白纤维、壳聚糖纤维等冻干纤维均有此种特性,所以其均可以“脱离”基质,但本身又都具有“成膜性”,所以可以“脱离基质”后“再成膜”。使用干巾时,利用少量水浸湿后,在表皮上一擦即可,在擦拭过程中所述冻干膜层与基布载体层剥离,在表皮上脱水重新成膜,成膜后即可起到相应效果,使用方法简便,避免了长时间佩戴带来的不便。4. Freeze-dried effects, freeze-dried skin feel agents and freeze-dried fibers are not strong enough to bind the carrier layer of the base fabric. After selecting ketoprofen, scutellaria root extract, epidermal growth factor, milk protein and other freeze-dried effects, Freeze-dried skin feel agents such as soluble glycoprotein, fructan, propylene glycol, hydrogenated palm oil, sodium polyglutamate, and freeze-dried fibers such as collagen fiber and chitosan fiber have this characteristic, so they can all "Matrix, but it also has "film-forming properties", so it can "break away from the matrix" and then "form a film." When using a dry towel, wet it with a small amount of water and wipe it on the epidermis. During the wiping process, the freeze-dried film layer is peeled off from the carrier layer of the base cloth and dehydrated on the epidermis to form a film again. The corresponding effect is achieved, the method of use is simple, and the inconvenience caused by long-term wearing is avoided.
具体实施方式detailed description
以下结合具体实施例对本发明作进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。The present invention will be further described in detail below in conjunction with specific embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, but not to limit the present invention.
实施例1Example 1
一种干巾,包括基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.01ml/cm 2的水接触,所述冻干膜层可在10s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述冻干膜层的厚度为100μm。所述基布载体层的形状为圆形无纺布,所述冻干膜层包括冻干功效物、冻干肤感剂及冻干纤维,所述冻干功效物为牛奶蛋白、乙酰基六肽-1、芽孢杆菌发酵产物,所述冻干肤感剂为透明质酸钠、聚谷氨酸钠,所述冻干纤维为胶原蛋白纤维。 A dry towel, comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel is in contact with 0.01 ml/cm 2 of water, the freeze-dried film layer It can be dissolved within 10s, and the dissolution rate of the lyophilized product can reach more than 90% within 1 min. The thickness of the freeze-dried film layer is 100 μm. The shape of the base fabric carrier layer is a circular non-woven fabric, the freeze-dried film layer includes freeze-dried functional substances, freeze-dried skin feel agents and freeze-dried fibers, and the freeze-dried functional substances are milk protein, acetyl six Peptide-1, Bacillus fermentation product, the freeze-dried skin feel agent is sodium hyaluronate, sodium polyglutamate, and the freeze-dried fiber is collagen fiber.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将10%牛奶蛋白、0.02%乙酰基六肽-1、0.1%芽孢杆菌发酵产物、0.1%透明质 酸钠、0.05%聚谷氨酸钠充分混合后溶于水,以600-800g/㎡的比例喷洒在45g/㎡的胶原蛋白纤维表面,充分浸润后,进行-50℃~-30℃真空冷冻干燥,形成100μm厚的冻干膜;Step 1: Mix 10% milk protein, 0.02% acetyl hexapeptide-1, 0.1% bacillus fermented product, 0.1% sodium hyaluronate, 0.05% sodium polyglutamate, and dissolve it in water, with 600-800g Sprayed on the surface of 45g/㎡ collagen fiber at a ratio of /㎡, fully infiltrated, and freeze-dried in vacuum at -50℃~-30℃ to form a 100μm thick lyophilized film;
步骤2:冻干膜与纯棉无纺布进行复合,形成精华干巾。Step 2: The freeze-dried film is combined with the pure cotton non-woven fabric to form the essence dry towel.
本实施例中的干巾作为精华干巾,护肤时使用。使用时,首先将所述干巾与水接触,冻干膜层溶解或溶出,然后在与表皮发生摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜,精华可起到护肤的作用。The dry towel in this embodiment is used as an essence dry towel for skin care. When in use, first contact the dry towel with water to dissolve or dissolve the lyophilized film layer, and then when rubbing against the epidermis, the lyophilized film layer is peeled off from the carrier layer of the base cloth and forms a film on the epidermis. The essence can be Play the role of skin care.
本实施例中的干巾的包装结构为多片集合式塑料盒装,外部套有铝塑袋。The packaging structure of the dry towel in this embodiment is a multi-piece assembled plastic box with an aluminum plastic bag on the outside.
在本实施例中调节冻干功效物、冻干肤感剂及冻干纤维的质量比,具体的,将步骤1调整为:将9%牛奶蛋白、0.5%乙酰基六肽-1、0.5%芽孢杆菌发酵产物、0.9%透明质酸钠、0.1%聚谷氨酸钠充分混合后溶于水,以1000g/㎡的比例喷洒在10g/㎡的胶原蛋白纤维表面,充分浸润后,进行-50℃~-30℃真空冷冻干燥。得到的精华干巾具有相同的效果。In this embodiment, the mass ratio of the freeze-dried efficacy substance, the freeze-dried skin feel agent, and the freeze-dried fiber is adjusted. Specifically, step 1 is adjusted to: 9% milk protein, 0.5% acetyl hexapeptide-1, 0.5% The fermentation product of Bacillus, 0.9% sodium hyaluronate and 0.1% sodium polyglutamate are thoroughly mixed and dissolved in water, and sprayed on the surface of the collagen fiber of 10g/㎡ at a ratio of 1000g/㎡. After fully infiltrating, proceed to -50 ℃~-30℃ vacuum freeze drying. The obtained essence dry towel has the same effect.
对比例1-1:使用实施例1的类似配方制作。Comparative Example 1-1: Prepared using the similar formula of Example 1.
一种普通精华面膜,配方为水(至100%),10%牛奶蛋白、0.02%乙酰基六肽-1、0.1%芽孢杆菌发酵产物、0.1%透明质酸钠、0.05%聚谷氨酸钠、0.5%苯氧乙醇、0.2%尼泊金甲酯、0.2%聚山梨醇酯80。An ordinary essence mask, the formula is water (to 100%), 10% milk protein, 0.02% acetyl hexapeptide-1, 0.1% bacillus fermentation product, 0.1% sodium hyaluronate, 0.05% sodium polyglutamate , 0.5% phenoxyethanol, 0.2% methyl paraben, 0.2% polysorbate 80.
膜布为纯棉无纺布,包装一般为多片式塑料盒装。The membrane cloth is pure cotton non-woven cloth, and the packaging is generally in a multi-piece plastic box.
使用时,由于成分含有防腐剂,对表皮产生一定刺激性,不慎入眼后有刺痛感。When used, because the ingredients contain preservatives, it will cause a certain irritation to the epidermis, and it will sting after accidentally entering the eyes.
家兔多次皮肤刺激性试验表明,实施例1的干巾为“无刺激”,对比例1的面膜为“轻微刺激”。Multiple skin irritation tests of rabbits showed that the dry towel of Example 1 was "no irritation", and the facial mask of Comparative Example 1 was "slightly irritating".
针对牛奶蛋白、乙酰基六肽-1的含量追踪测试结果表明,产品封装后,将实施例1的干巾和对比例1的面膜置于相同阴凉库中1年后,实施例1中的牛奶蛋白和乙酰基六肽-1的含量损失低于5%,对比例1的面膜中牛奶蛋白损失20%,乙酰基六肽-1损失35%;对于活性物的稳定性具有显著差异。The tracking test results for the content of milk protein and acetyl hexapeptide-1 show that after the product is packaged, the dry towel of Example 1 and the facial mask of Comparative Example 1 are placed in the same cool storage for 1 year, the milk in Example 1 The content loss of protein and acetyl hexapeptide-1 is less than 5%, the milk protein loss of comparative example 1 is 20%, and the acetyl hexapeptide-1 loss is 35%; there is a significant difference in the stability of the active substance.
使用皮肤快速水分检测仪进行表皮含水量检测,实施例1中的干巾在表皮擦拭5次后(用时15s),表皮含水量从初始值28%提升至56%;对比例1中面膜敷面15s后,表皮含水量从初始值28%提升至32%,敷面5min后,表皮含水量从初始值28%提升至53%。可以看出,精华干巾由于在皮肤表面快速成膜,有效提高了皮肤水合度。A rapid skin moisture detector was used to detect the moisture content of the epidermis. After the dry towel in Example 1 was wiped 5 times (15s), the moisture content of the epidermis increased from the initial value of 28% to 56%; the facial mask in Comparative Example 1 After 15s, the skin moisture content increased from the initial value of 28% to 32%. After 5 minutes of application, the skin moisture content increased from the initial value of 28% to 53%. It can be seen that the essence dry towel can effectively improve skin hydration due to its rapid film formation on the skin surface.
对比例1-2Comparative example 1-2
补水保湿精华湿巾(品牌:丽得姿,市售):其配方中含有:水,丁二醇、丙二醇、双丙甘醇(防腐)、1,2己二醇(防腐)、马齿苋提取物、尿囊素、辛酸癸酸甘油三酯、乙基己基甘油、银耳提取物、木糖醇、EDTA二钠、葡萄糖酸内酯、番木瓜果提取物、葡萄糖、水杨酸。该市售湿巾中含有大量具有防腐功能的多元醇,具有一定刺激性,而且擦拭后没有成膜,很快会挥发掉,让精华成分难以停留。Moisturizing essence wet wipes (brand: Li Dezi, commercially available): Its formula contains: water, butylene glycol, propylene glycol, dipropylene glycol (preservative), 1,2 hexanediol (preservative), portulaca Extract, Allantoin, Caprylic Capric Triglyceride, Ethylhexyl Glycerin, Tremella Extract, Xylitol, Disodium EDTA, Gluconolactone, Papaya Fruit Extract, Glucose, Salicylic Acid. The commercially available wet wipes contain a large amount of antiseptic polyols, which are irritating, and there is no film formation after wiping, and they will evaporate quickly, making it difficult for the essence to stay.
实施例2Example 2
一种干巾,包括基布载体层、以冷冻干燥形式附着在所述基布载体层上的冻干膜层和离型层,所述干巾与0.1ml/cm 2的水接触,所述基布载体层的形状为方形无纺布,材质为天丝,所述冻干膜层可在5s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述冻干膜层的厚度为300μm。所述冻干膜层为冻干功效物,所述冻干功效物为无患子提取物、椰油基甜菜碱、月桂酰谷氨酸钠、乙酰化透明质酸钠;所述离型层与基布载体层形状尺寸一致,材质为pu。 A dry towel, comprising a base fabric carrier layer, a freeze-dried film layer and a release layer attached to the base fabric carrier layer in a freeze-dried form, the dry towel is in contact with 0.1 ml/cm 2 of water, the The shape of the base fabric carrier layer is a square non-woven fabric, and the material is Tencel. The freeze-dried film layer can be dissolved within 5 seconds, and the dissolution rate of the freeze-dried functional substance reaches more than 90% within 1 min. The thickness of the freeze-dried film layer is 300 μm. The freeze-dried film layer is a freeze-dried functional substance, and the freeze-dried functional substance is a Sapindus extract, coco-betaine, sodium lauroyl glutamate, and sodium acetylated hyaluronate; the release layer It is consistent with the shape and size of the base cloth carrier layer, and the material is pu.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将15%无患子提取物、5%椰油基甜菜碱、3%月桂酰谷氨酸钠、0.1%乙酰化透明质酸钠溶于水,脱泡,喷洒于基布表面,进行-50℃~-30℃真空冷冻干燥,形成300μm后的冻干膜层;Step 1: Dissolve 15% soapberry extract, 5% coco-betaine, 3% sodium lauroyl glutamate, and 0.1% sodium acetylated hyaluronate in water, defoam and spray on the surface of the base cloth, Carry out -50℃~-30℃ vacuum freeze-drying to form a freeze-dried film layer after 300μm;
步骤2:与离型层复合形成终产品。Step 2: Compound with the release layer to form the final product.
本实施例中的干巾作为卸妆洁面干巾使用。使用时,首先将所述干巾与水接触,冻干膜层溶解或溶出,然后在与表皮擦拭时,所述冻干膜层与基布载体层剥离,在表皮上成膜,成膜后可溶解皮肤表面彩妆、污渍等作为卸妆清洁干巾使用,并可进一步深度洁面。The dry towel in this embodiment is used as a makeup remover and cleansing towel. When in use, first contact the dry towel with water to dissolve or dissolve the freeze-dried film layer, and then when wiping with the epidermis, the freeze-dried film layer is peeled off from the base cloth carrier layer, and a film is formed on the epidermis. It can dissolve makeup, stains, etc. on the skin's surface and use it as a dry wipe for cleansing makeup, and can further clean the face.
本实施例中的干巾的包装结构为多片集合式铝塑袋装。The packaging structure of the dry towel in this embodiment is a multi-piece assembled aluminum-plastic bag.
对比例2-1:使用实施例2的类似配方进行制作。Comparative Example 2-1: Use the similar formula of Example 2 to make.
一种卸妆水,包含水(至100%)、15%无患子提取物、5%椰油基甜菜碱、3%月桂酰谷氨酸钠、0.1%乙酰化透明质酸钠溶、0.3%甲基异噻唑啉酮。A cleansing water, containing water (to 100%), 15% Sapindus extract, 5% coco betaine, 3% sodium lauroyl glutamate, 0.1% sodium acetylated hyaluronate, 0.3% Methyl isothiazolinone.
使用天丝材质的卸妆棉片,每片吸收约5g上述卸妆水,单次卸妆使用量为6张卸妆棉片,使用后还需另外搭配洗面奶进行洁面。由于大量接触表面活性剂,每日卸妆后皮肤干燥、角质层变薄、易敏感,产生其他皮肤问题。Using Tencel makeup remover pads, each piece absorbs about 5g of the above makeup remover water, and the single use amount for makeup remover is 6 makeup remover pads. After use, it needs to be cleaned with facial cleanser. Due to extensive exposure to surfactants, the skin becomes dry, the stratum corneum becomes thinner, and sensitive to other skin problems after daily makeup removal.
使用实施例2的卸妆干巾,单次卸妆需要2片,溶出在皮肤表面成膜后,再次加水可以作为洗面奶使用,大量降低了表面活性剂与皮肤的接触量,保护了皮肤水油平衡。Using the cleansing dry towel of Example 2, 2 pieces are needed for a single cleansing. After dissolving on the skin surface and forming a film, add water again to use as a facial cleanser, which greatly reduces the amount of surfactant contact with the skin and protects the skin's water and oil balance .
同时,由于不含有防腐剂,对皮肤温和不刺激,可每日使用。At the same time, because it does not contain preservatives, it is gentle and non-irritating to the skin, and can be used daily.
对比例2-2Comparative example 2-2
卸妆洁面片湿巾(品牌:琴叶,市售):其配方中含有:水,月桂酰谷氨酸钠、月桂酰谷氨酸钾、椰油酰谷氨酸钠、PVP/PVA丙酸乙烯酯共聚物、蜂王浆、甘油、吡咯烷酮羧酸、丁二醇、苯氧乙醇、葡萄叶提取物、北美金缕梅提取物、欧锦葵提取物、黄瓜果提取物、库拉索芦荟叶提取物、贯叶连翘提取物。该市售湿巾虽然是湿巾形式,每次使用还需要加水,单侧使用3片之后才有比较明显的卸妆效果,而且由于配方中含有苯氧乙醇防腐剂,对皮肤有刺激作用。Makeup remover cleansing sheet wipes (brand: Qinye, commercially available): Its formula contains: water, sodium lauroyl glutamate, potassium lauroyl glutamate, sodium cocoyl glutamate, PVP/PVA vinyl propionate Ester copolymer, royal jelly, glycerin, pyrrolidone carboxylic acid, butanediol, phenoxyethanol, grape leaf extract, witch hazel extract, mallow extract, cucumber fruit extract, aloe vera leaf extract, Hypericum perforatum extract. Although the commercially available wet wipes are in the form of wet wipes, they need to be added with water each time they are used. Only after 3 sheets are used on one side can they have a clear makeup removal effect. Moreover, the formula contains phenoxyethanol preservatives, which have irritating effects on the skin.
实施例3Example 3
一种干巾,包括基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.0005ml/cm 2的水接触,所述冻干膜层可在7s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述基布载体层的形状为方形无纺布,材质为脱脂棉及纯棉无纺布复合材质,所述冻干膜层的厚度为5μm。所述冻干膜层包括冻干功效物和冻干肤感剂,所述冻干功效物为小分子透明质酸钠;所述冻干肤感剂为氢化棕榈油、聚甘油油酸酯。 A dry towel, comprising a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form, the dry towel is in contact with 0.0005 ml/cm 2 of water, the freeze-dried film layer It can be dissolved in 7s, and the dissolution rate of the lyophilized product can reach more than 90% in 1 min. The shape of the base fabric carrier layer is a square non-woven fabric, and the material is a composite material of absorbent cotton and pure cotton non-woven fabric, and the thickness of the freeze-dried film layer is 5 μm. The freeze-dried film layer includes a freeze-dried functional substance and a freeze-dried skin feel agent. The freeze-dried functional substance is a small molecule sodium hyaluronate; the freeze-dried skin feel agent is hydrogenated palm oil and polyglyceryl oleate.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1.将小分子透明质酸钠分散于氢化棕榈油中,分散质量比例为1:9;Step 1. Disperse the small molecule sodium hyaluronate in hydrogenated palm oil with a mass ratio of 1:9;
步骤2.将混合物加温至47℃熔融至具有流动性,加入聚甘油油酸酯,其与混合物的比例1:1;Step 2. Heat the mixture to 47°C to melt until it has fluidity, and add polyglycerol oleate, the ratio of which to the mixture is 1:1;
步骤3.涂布于基布表面,进行-50℃-20℃真空冷冻干燥,使混合物凝固,并脱除吸潮水分,形成5μm厚的冻干膜。Step 3. Coating on the surface of the base fabric and performing vacuum freeze drying at -50°C to 20°C to solidify the mixture and remove moisture absorption to form a 5 μm thick freeze-dried film.
本实施例中的干巾作为敷料贴片使用。使用时,首先将所述干巾与伤口中的极少渗出液或皮肤散发的水蒸气接触,冻干膜层溶解或溶出,所述冻干膜层与基布载体层剥离,在皮肤创面、隔离创面上成膜,形成液态创口贴。The dry towel in this embodiment is used as a dressing patch. When in use, first contact the dry towel with minimal exudate in the wound or water vapor emitted from the skin, the freeze-dried film layer is dissolved or dissolved, the freeze-dried film layer is peeled from the base cloth carrier layer, and the skin wound , Form a film on the isolated wound to form a liquid wound patch.
本实施例中的干巾的包装结构为单片式铝塑袋装。The packaging structure of the dry towel in this embodiment is a single-piece aluminum-plastic bag.
在本实施例中,对各配方含量做出如下调整:步骤1.将小分子透明质酸钠分散于氢化棕榈油中,分散质量分别为10g和0.2g;步骤2.将混合物加温至47℃熔融至具有流动性,加入聚甘油油酸酯0.8g;步骤3.涂布于基布表面,进行-50℃-20℃真空冷冻干燥,使混合物凝固,并脱除吸潮水分,形成5μm厚的冻干膜。得到的液态创口贴具有相同的效果。In this example, the content of each formula was adjusted as follows: Step 1. Disperse small molecule sodium hyaluronate in hydrogenated palm oil, the dispersion masses were 10g and 0.2g respectively; Step 2. Heat the mixture to 47 Melt at ℃ to fluidity, add 0.8g of polyglycerol oleate; Step 3. Coat on the surface of the base fabric, and freeze-dry at -50℃-20℃ to make the mixture solidify and remove moisture to form 5μm Thick freeze-dried film. The obtained liquid wound patch has the same effect.
再调整各组成含量如下:小分子透明质酸钠分散于氢化棕榈油中,分散质量分别为1g和25g,加入聚甘油油酸酯5g;或者小分子透明质酸钠分散于氢化棕榈油中,分散质量分别为30g和0.7g,加入聚甘油油酸酯0.3g,得到的液态创口贴效果相同。Then adjust the content of each composition as follows: small molecule sodium hyaluronate is dispersed in hydrogenated palm oil, the dispersion mass is 1g and 25g respectively, and 5g polyglycerol oleate is added; or small molecule sodium hyaluronate is dispersed in hydrogenated palm oil, The dispersion mass is 30g and 0.7g respectively, and 0.3g of polyglyceryl oleate is added, and the liquid wound patch obtained has the same effect.
对比例3:使用实施例3的类似配方进行制作。Comparative Example 3: Using the similar formula of Example 3 to make.
一种液态创口贴,包含聚甘油油酸酯5%、氢化棕榈油4.5%、小分子透明质酸钠0.5%、对羟基苯乙酮0.5%,水(至100%)。使用时需要挤出5-10g于患处,且包装难以再次密封,包装开启后保质期2个月。A liquid wound plaster contains 5% polyglycerol oleate, 4.5% hydrogenated palm oil, 0.5% small molecule sodium hyaluronate, 0.5% p-hydroxyacetophenone, and water (to 100%). It is necessary to squeeze 5-10g into the affected area during use, and the package is difficult to reseal. The shelf life of the package is 2 months after opening.
家兔多次皮肤刺激性试验表明,实施例3的干巾为“无刺激”,对比例3的液态创口贴为“轻微刺激”。Multiple skin irritation tests of rabbits showed that the dry towel of Example 3 was "no irritation", and the liquid wound patch of Comparative Example 3 was "slightly irritating".
在对比例3的创口贴的配制过程中需要大量水(89.5%)可以达到成膜效果;实施例3中的干巾仅需要伤口中极少的渗出液即可溶出成膜,起到隔离作用。In the preparation process of the wound patch of Comparative Example 3, a large amount of water (89.5%) is needed to achieve the film-forming effect; the dry towel in Example 3 only needs very little exudate from the wound to dissolve and form a film to isolate effect.
实施例4Example 4
一种干巾,包括基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.001ml/cm 2的水接触,所述基布载体层的形状为方形无纺布,材质为铜氨纤维和莫代尔纤维混纺,所述冻干膜层可在3s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述冻干膜层的厚度为0.1μm。所述冻干膜层包括冻干功效物、冻干肤感剂和冻干纤维,所述冻干功效物为酮洛芬,所述冻干肤感剂为卡波姆和甘油,所述冻干纤维为壳聚糖纤维。 A dry towel, comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel is in contact with 0.001 ml/cm 2 of water, and the base cloth carrier layer The shape of is a square non-woven fabric, and the material is a blend of cupra fiber and modal fiber. The freeze-dried film layer can be dissolved within 3s, and the dissolution rate of the freeze-dried functional substance reaches more than 90% within 1 min. The thickness of the freeze-dried film layer is 0.1 μm. The freeze-dried film layer includes a freeze-dried functional substance, a freeze-dried skin feel agent and a freeze-dried fiber, the freeze-dried functional substance is ketoprofen, the freeze-dried skin feel agent is carbomer and glycerin, and the freeze-dried The dry fiber is chitosan fiber.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将酮洛芬1%、卡波姆0.5%和甘油10%加水(至100%)溶解,调节ph至5.5具有一定凝胶粘度(>300cp)后,以200-350g/㎡的比例涂布在50g/㎡的壳聚糖纤维表面,-50℃~-25℃真空冷冻干燥形成冻干膜层;Step 1: Dissolve ketoprofen 1%, carbomer 0.5% and glycerol 10% with water (to 100%), adjust the pH to 5.5 and have a certain gel viscosity (>300cp), and then use the ratio of 200-350g/㎡ Coated on the surface of 50g/㎡ chitosan fiber and freeze-dried in vacuum at -50℃~-25℃ to form a freeze-dried film layer;
步骤2:冻干膜层与铜氨/莫代尔混纺基布复合,形成阵痛外用药干巾。Step 2: The freeze-dried film layer is combined with the cupra/modal blended fabric base fabric to form a dry towel for external pain medication.
本实施例中的干巾作为透皮外用药贴片使用。使用时,首先将所述干巾与少量水接触(比如散发的水蒸气接触),冻干膜层溶解或溶出,然后在与表皮发生摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜,有效成分通过透皮吸收的形式被利用。The dry towel in this embodiment is used as a transdermal external medication patch. When in use, the dry towel is first contacted with a small amount of water (such as the emitted water vapor contact), the freeze-dried film layer is dissolved or dissolved, and then when rubbing with the skin, the freeze-dried film layer and the base fabric carrier layer are peeled off , It forms a film on the epidermis, and the active ingredients are used in the form of transdermal absorption.
本实施例中的干巾的包装结构为单片装铝塑泡罩装。The packaging structure of the dry towel in this embodiment is a single piece of aluminum-plastic blister pack.
在本实施例的基础上对步骤1中成分进行调整,调整后的步骤1为:将酮洛芬1%、卡波姆5%和甘油45%加水(至100%)溶解,调节ph至5.5具有一定凝胶粘度(>300cp)后,以100g/㎡的比例涂布在100g/㎡的壳聚糖纤维表面,-50℃~-25℃真空冷冻干燥形成冻干膜层.The ingredients in step 1 are adjusted on the basis of this example. The adjusted step 1 is: dissolve ketoprofen 1%, carbomer 5% and glycerol 45% with water (to 100%), and adjust the pH to 5.5 After having a certain gel viscosity (>300cp), it is coated on the surface of 100g/㎡ chitosan fiber at a ratio of 100g/㎡, and freeze-dried under vacuum at -50℃~-25℃ to form a freeze-dried film layer.
或者调整后的步骤1为:将酮洛芬1%、卡波姆5%和甘油45%加水(至100%)溶解,调节ph至5.5具有一定凝胶粘度(>300cp)后,以100g/㎡的比例涂布在0.1g/㎡的壳聚糖纤维表面,-50℃~-25℃真空冷冻干燥形成冻干膜层。在此调整的基础上,均可获得以上效果的透皮外用药贴片。Or step 1 after adjustment: Dissolve ketoprofen 1%, carbomer 5% and glycerol 45% with water (to 100%), adjust the pH to 5.5 and have a certain gel viscosity (>300cp), and then use 100g/ The ratio of ㎡ is coated on the surface of 0.1g/㎡ chitosan fiber, and it is vacuum freeze-dried at -50℃~-25℃ to form a freeze-dried film layer. On the basis of this adjustment, transdermal topical medicinal patches with the above effects can be obtained.
或者调整后的步骤1为:将酮洛芬30%、卡波姆5%和甘油45%加水(至100%)溶解,调节ph至5.5具有一定凝胶粘度(>300cp)后,以100g/㎡的比例涂布在0.1g/㎡的壳聚糖纤维表面,-50℃~-25℃真空冷冻干燥形成冻干膜层。在此调整的基础上,均可获得以上效果的透皮外用药贴片。Or step 1 after adjustment: Dissolve ketoprofen 30%, carbomer 5% and glycerol 45% with water (to 100%), adjust the pH to 5.5 and have a certain gel viscosity (>300cp), and then use 100g/ The ratio of ㎡ is coated on the surface of 0.1g/㎡ chitosan fiber, and it is vacuum freeze-dried at -50℃~-25℃ to form a freeze-dried film layer. On the basis of this adjustment, transdermal topical medicinal patches with the above effects can be obtained.
或者调整后的步骤1为:将酮洛芬30%、卡波姆5%和甘油45%加水(至100%)溶解,调节ph至5.5具有一定凝胶粘度(>300cp)后,以100g/㎡的比例涂布在100g/㎡的壳聚糖纤维表面,-50℃~-25℃真空冷冻干燥形成冻干膜层。在此调整的基础上,均可获得以上效果的透皮外用药贴片。Or step 1 after adjustment: Dissolve ketoprofen 30%, carbomer 5% and glycerol 45% with water (to 100%), adjust the pH to 5.5 and have a certain gel viscosity (>300cp), and then use 100g/ The ratio of ㎡ is coated on the surface of 100g/㎡ chitosan fiber and freeze-dried in vacuum at -50℃~-25℃ to form a freeze-dried film layer. On the basis of this adjustment, transdermal topical medicinal patches with the above effects can be obtained.
对比例4:使用实施例4的类似配方制作。Comparative Example 4: Manufactured using the similar formula of Example 4.
酮洛芬1%、卡波姆0.5%和甘油10%加水(至100%)溶解,调节ph至5.5具有一定凝胶粘度(>300cp)后,直接涂布于壳聚糖纤维表面,以铜氨/莫代尔混纺基布复合后包装作 为外用药使用。Ketoprofen 1%, carbomer 0.5% and glycerol 10% are dissolved in water (to 100%), adjusted to pH 5.5 and have a certain gel viscosity (>300cp), and then directly coated on the surface of chitosan fiber with copper Ammonia/Modal blended fabric is compounded and packaged for external use.
透皮试验检测药物溶出度结果表明,实施例4酮洛芬在4小时内溶出比率为3.72%,对比例4酮洛芬在4小时内溶出比率为1.89%,具有显著差异。The results of transdermal test detection of drug dissolution showed that the dissolution rate of ketoprofen in Example 4 was 3.72% within 4 hours, and the dissolution rate of ketoprofen in Comparative Example 4 was 1.89% within 4 hours, which is a significant difference.
实施例5Example 5
一种干巾,包括离型层、基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.05ml/cm 2的水接触,所述冻干膜层可在6s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述基布载体层的形状为椭圆形无纺布,材质为30%海藻纤维,所述离型层形状和大小与所述基布载体层相同,材质为pet,所述冻干膜层的厚度为30μm。所述冻干膜层包括冻干功效物、冻干肤感剂及冻干纤维,所述冻干功效物为烟酰胺、黄芩根提取物,所述冻干肤感剂为可溶性糖蛋白、聚山梨醇酯80、辛酸/癸酸甘油三酯,所述冻干纤维为35g/㎡的羧甲基纤维素纤维。 A dry towel, comprising a release layer, a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form. The dry towel is in contact with 0.05 ml/cm 2 of water, and the The lyophilized film layer can be dissolved in 6 seconds, and the dissolution rate of the lyophilized product can reach more than 90% within 1 min. The shape of the base fabric carrier layer is an oval non-woven fabric, the material is 30% seaweed fiber, the shape and size of the release layer are the same as the base fabric carrier layer, and the material is pet. The thickness is 30 μm. The freeze-dried film layer includes a freeze-dried functional substance, a freeze-dried skin feel agent, and a freeze-dried fiber, the freeze-dried functional substance is nicotinamide, a scutellaria root extract, and the freeze-dried skin feel agent is a soluble glycoprotein, a poly Sorbitol ester 80, caprylic acid/capric acid triglyceride, and the freeze-dried fiber is 35 g/㎡ carboxymethyl cellulose fiber.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将烟酰胺3%、黄芩根提取物1%、可溶性糖蛋白1%、聚山梨醇酯80 1.5%、辛酸/癸酸甘油三酯2%加水溶解、乳化均质均匀,与35g/㎡羧甲基纤维素纤维相互浸润,-50℃~-25℃真空冷冻干燥,形成冻干膜层;Step 1: Dissolve nicotinamide 3%, Scutellaria baicalensis root extract 1%, soluble glycoprotein 1%, polysorbate 80 1.5%, caprylic acid/capric triglyceride 2% in water, emulsify and homogenize, and 35g/ ㎡ Carboxymethyl cellulose fibers infiltrate each other and freeze-dried in vacuum at -50℃~-25℃ to form a freeze-dried film layer
步骤2:冻干膜层与海藻纤维基布载体复合,形成亮肤精华干巾。Step 2: The freeze-dried film layer is combined with the seaweed fiber base cloth carrier to form a dry skin lightening essence towel.
本实施例中的干巾作为护肤精华干巾使用。使用时,首先在所述干巾表面喷洒及其少量的水,冻干膜层溶解或溶出,然后在与表皮发生摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜,起到护肤的目的。The dry towel in this embodiment is used as a skin care essence dry towel. When in use, first spray a small amount of water on the surface of the dry towel to dissolve or dissolve the freeze-dried film layer, and then when rubbing against the epidermis, the freeze-dried film layer is peeled off from the base fabric carrier layer, forming a layer on the epidermis. The membrane serves the purpose of skin care.
本实施例中的干巾的包装结构为密封袋装。The packaging structure of the dry towel in this embodiment is a sealed bag.
在本实施例的基础上,对步骤1中各组分含量进行调整,具体为将烟酰胺0.9%、黄芩根提取物0.1%、可溶性糖蛋白0.01%、聚山梨醇酯80 0.07%、辛酸/癸酸甘油三酯0.02%加水溶解、乳化均质均匀,将100g乳化均匀后的混合物得到与100g/㎡羧甲基纤维素纤维1m 2相互浸润,-50℃~-25℃真空冷冻干燥,形成冻干膜层;通过此得到的护肤精华干巾与上述效果相同。 On the basis of this example, the content of each component in step 1 was adjusted, specifically, nicotinamide 0.9%, scutellaria root extract 0.1%, soluble glycoprotein 0.01%, polysorbate 80 0.07%, caprylic acid/ Capric triglyceride 0.02% is dissolved in water and emulsified uniformly. The 100g emulsified mixture is infiltrated with 100g/㎡ carboxymethyl cellulose fiber 1m 2 and freeze-dried under vacuum at -50℃~-25℃ to form Freeze-dried film layer; the skin care essence dry towel obtained by this has the same effect as the above.
同样的对各组分做以下修改时,同样得到相同效果的干巾:将烟酰胺0.2%、黄芩根提取物0.1%、可溶性糖蛋白0.1%、聚山梨醇酯80 0.3%、辛酸/癸酸甘油三酯0.1%加水溶解、乳化均质均匀,将10000g乳化均匀后的混合物得到与100g/㎡羧甲基纤维素纤维1m 2相互浸润,-50℃~-25℃真空冷冻干燥,形成冻干膜层。 When the following modifications are made to each component, the same dry towel will be obtained: Niacinamide 0.2%, Scutellaria baicalensis root extract 0.1%, soluble glycoprotein 0.1%, polysorbate 80 0.3%, caprylic/capric acid 0.1% triglyceride is dissolved in water and emulsified uniformly. The 10000g emulsified mixture is infiltrated with 100g/㎡ carboxymethyl cellulose fiber 1m 2 and freeze-dried in vacuum at -50℃~-25℃ to form freeze-dried膜层。 Film layer.
对比例5:使用实施例5的类似配方进行制作。Comparative Example 5: Use the similar formula of Example 5 to make.
一种普通亮肤精华面膜,配方为水(至100%),烟酰胺3%、黄芩根提取物1%、可溶性糖蛋白1%、聚山梨醇酯80 1.5%、辛酸/癸酸甘油三酯2%、0.5%苯氧乙醇、0.2%尼泊金甲酯、0.1%聚山梨醇酯80。An ordinary skin lightening essence mask, the formula is water (to 100%), niacinamide 3%, scutellaria root extract 1%, soluble glycoprotein 1%, polysorbate 80 1.5%, caprylic/capric triglyceride 2%, 0.5% phenoxyethanol, 0.2% methyl paraben, 0.1% polysorbate 80.
膜布为30%海藻纤维,包装为多片式塑料盒装。The membrane cloth is 30% seaweed fiber, and the packaging is multi-piece plastic box.
使用时,由于成分含有防腐剂,对表皮产生一定刺激性,不慎入眼后有刺痛感。When used, because the ingredients contain preservatives, it will cause a certain irritation to the epidermis, and it will sting after accidentally entering the eyes.
家兔多次皮肤刺激性试验表明,实施例1的干巾为“无刺激”,对比例1的面膜为“轻微刺激”。Multiple skin irritation tests of rabbits showed that the dry towel of Example 1 was "no irritation", and the facial mask of Comparative Example 1 was "slightly irritating".
针对烟酰胺、黄芩根提取物的含量追踪测试结果表明,产品封装后,将实施例5的干巾和对比例5的面膜置于相同阴凉库中1年后,实施例1中的烟酰胺和黄芩根提取物的含量损失低于4%,对比例5的面膜中烟酰胺损失24%,黄芩根提取物28%;对于活性物的稳定性具有显著差异。The tracking test results for the content of nicotinamide and scutellaria root extract showed that after the product was packaged, the dry towel of Example 5 and the facial mask of Comparative Example 5 were placed in the same cool storage for 1 year, and the nicotinamide in Example 1 and The content loss of Scutellaria baicalensis Root extract was less than 4%, the nicotinamide in the facial mask of Comparative Example 5 lost 24%, and the Scutellaria baicalensis Root extract 28%; there was a significant difference in the stability of the active substance.
使用皮肤快速水分检测仪进行表皮含水量检测,实施例1中的干巾在表皮擦拭5次后(用时15s),表皮含水量从初始值26%提升至49%;对比例1中面膜敷面15s后,表皮含水量从初始值26%提升至30%,敷面5min后,表皮含水量从初始值28%提升至45%。可以看出,精华干巾由于在皮肤表面快速成膜,有效提高了皮肤水合度。A rapid skin moisture detector was used to detect the moisture content of the epidermis. After the dry towel in Example 1 was wiped 5 times (15s), the moisture content of the epidermis increased from the initial value of 26% to 49%; in Comparative Example 1, the facial mask was applied. After 15 seconds, the skin moisture content increased from the initial value of 26% to 30%, and after 5 minutes of application, the skin moisture content increased from the initial value of 28% to 45%. It can be seen that the essence dry towel can effectively improve skin hydration due to its rapid film formation on the skin surface.
实施例6Example 6
一种干巾,包括离型层、基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.0001ml/cm 2的水接触,所述冻干膜层可在8s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述基布载体层的形状为眼罩型无纺布,材质为竹纤维与天丝的混纺纤维,所述离型层形状和大小与所述基布载体层相同,材质为pp,所述冻干膜层的厚度为1μm。所述冻干膜层由冻干功效物和冻干肤感剂组成,所述冻干功效物为橙皮苷、加拿大红枫提取物、乙酰基四肽-2,所述冻干肤感剂为聚甘油-10甘油酯、果聚糖、羟乙基脲。 A dry towel, comprising a release layer, a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form. The dry towel is in contact with 0.0001 ml/cm 2 of water, and the The freeze-dried film layer can be dissolved in 8 seconds, and the dissolution rate of the freeze-dried effective substance reaches more than 90% within 1 min. The shape of the base fabric carrier layer is an eye mask type non-woven fabric, and the material is a blended fiber of bamboo fiber and tencel. The shape and size of the release layer are the same as the base fabric carrier layer, and the material is pp. The thickness of the dry film layer is 1 μm. The freeze-dried film layer is composed of a freeze-dried functional substance and a freeze-dried skin feel agent, the freeze-dried functional substance is hesperidin, Canadian red maple extract, acetyl tetrapeptide-2, the freeze-dried skin feel agent It is polyglycerol-10 glyceride, fructan, and hydroxyethyl urea.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将橙皮苷1%、加拿大红枫提取物0.5%、乙酰基四肽-2 0.001%、聚甘油-10甘油酯0.5%、果聚糖0.5%、羟乙基脲5%加水(至100%)溶解,喷洒于基布表面,-50℃~-25℃真空冷冻干燥;Step 1: Add hesperidin 1%, Canadian red maple extract 0.5%, acetyl tetrapeptide-2 0.001%, polyglycerol-10 glyceride 0.5%, fructan 0.5%, and hydroxyethyl urea 5% with water ( To 100%) dissolve, spray on the surface of the base cloth, freeze-dry under vacuum at -50℃~-25℃;
步骤2:与pp离型层复合形成终产品。Step 2: Compound with the pp release layer to form the final product.
本实施例中的干巾作为眼周皮肤护理巾使用,产品在组合时,缝制于蒸汽眼罩内测表面,并单片独立包装。使用时,蒸汽眼罩会产生0.0001ml/cm 2的水蒸汽,与内测表面的护理巾接触后,冻干膜层溶解、溶出,与基布载体层剥离,在眼周表皮上成膜,得到眼周皮肤护理的结果。 The dry towel in this embodiment is used as a skin care towel around the eyes. When the product is assembled, it is sewn on the inner surface of the steam eye mask and is packaged as a single piece. When in use, the steam eye mask will generate 0.0001ml/cm 2 of water vapor. After contact with the care towel on the inner surface, the freeze-dried film layer is dissolved and dissolved, peeled off from the carrier layer of the base cloth, and a film is formed on the epidermis around the eye. The result of skin care around the eyes.
本实施例中的干巾的包装结构为密封袋包装。The packaging structure of the dry towel in this embodiment is a sealed bag packaging.
对比例6:使用实施例6的类似配方进行制作。Comparative Example 6: Use the similar formula of Example 6 to make.
一种眼周护理用湿巾,包括离型层和湿巾,所述湿巾中护理液的配方为水(至100%),橙皮苷1%、加拿大红枫提取物0.5%、乙酰基四肽-2 0.001%、聚甘油-10甘油酯0.5%、果聚 糖0.5%、羟乙基脲5%、0.2%尼泊金甲酯、0.1%聚山梨醇酯80。A wet wipe for eye care, comprising a release layer and a wet wipe. The formula of the care solution in the wet wipe is water (to 100%), hesperidin 1%, Canadian red maple extract 0.5%, acetyl group Tetrapeptide-2 0.001%, polyglycerol-10 glyceride 0.5%, fructan 0.5%, hydroxyethyl urea 5%, 0.2% methyl paraben, 0.1% polysorbate 80.
使用皮肤快速水分检测仪进行表皮含水量检测,将实施例6中的眼周皮肤护理巾在眼部按压或按摩5次后,眼周皮肤含水量从27%提升至50%,而对比例中的眼周护理湿巾在眼周湿敷15s后,眼周皮肤含水量从27%提升至34%,湿敷5min后,眼周皮肤含水量提升至46%。Using a rapid skin moisture detector to detect epidermal moisture content, after pressing or massaging the eye skin care towel in Example 6 for 5 times, the moisture content of the skin around the eyes increased from 27% to 50%, while the comparative example The moisture content of the eye skin care wipes increased from 27% to 34% after 15 seconds of wet application around the eyes, and increased to 46% after 5 minutes of wet application.
实施例7Example 7
一种干巾,包括离型层、基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.1ml/cm 2的水接触,所述冻干膜层可在9s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述基布载体层的形状为方形无纺布,材质为纯棉,所述离型层形状和大小与所述基布载体层相同,材质为pe,所述冻干膜层的厚度为85μm。所述冻干膜层包括冻干功效物、冻干肤感剂和冻干纤维,所述冻干功效物为脂肪酸酰胺烷基甜菜碱、冻干肤感剂为油醇、矿脂、聚甘油-10-硬脂酸酯,所述冻干纤维为水溶性海藻纤维。 A dry towel, comprising a release layer, a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form. The dry towel is in contact with 0.1 ml/cm 2 of water, and the The freeze-dried film layer can be dissolved in 9 seconds, and the dissolution rate of the freeze-dried functional substance reaches more than 90% within 1 min. The shape of the base fabric carrier layer is a square non-woven fabric, the material is pure cotton, the shape and size of the release layer are the same as the base fabric carrier layer, the material is pe, and the thickness of the freeze-dried film layer is 85 μm . The freeze-dried film layer includes a freeze-dried functional substance, a freeze-dried skin feel agent and a freeze-dried fiber, the freeze-dried functional substance is fatty acid amide alkyl betaine, and the freeze-dried skin feel agent is oleyl alcohol, petrolatum, and polyglycerin -10-stearate, the freeze-dried fiber is water-soluble seaweed fiber.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:脂肪酸酰胺烷基甜菜碱、分散到油醇中,分散比例为1:1;Step 1: Disperse fatty acid amide alkyl betaine into oleyl alcohol with a dispersion ratio of 1:1;
步骤2:将矿脂:聚甘油-10-硬脂酸酯=2:1的混合物加温到60℃熔融至具有流动性,并于步骤1混合物以1:1比例混合后,按照150-250g/㎡的比例涂布于50g/㎡的水溶性海藻纤维表面;Step 2: Heat the mixture of petrolatum: polyglycerol-10-stearate=2:1 to 60°C to melt until it has fluidity, and after mixing the mixture in step 1 at a ratio of 1:1, follow 150-250g Coated on the surface of 50g/㎡ water-soluble seaweed fiber at a ratio of /㎡;
步骤3:涂布于基布表面,-50℃~-20℃冷冻干燥。Step 3: Coating on the surface of the base cloth, freeze-drying at -50℃~-20℃.
本实施例中的干巾作为眼部卸妆干巾使用。使用时,首先将所述干巾与水接触,冻干膜层乳化、溶解和溶出,然后在与表皮发生摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜,溶解眼部彩妆后,通过继续擦拭进行擦除卸妆。The dry wipes in this embodiment are used as eye makeup remover dry wipes. When in use, the dry towel is first contacted with water to emulsify, dissolve and dissolve the lyophilized film layer, and then when rubbing against the epidermis, the lyophilized film layer is peeled off from the base fabric carrier layer to form a film on the epidermis, After dissolving the eye makeup, continue to wipe and remove the makeup.
利用本实施例的眼部卸妆干巾进行眼部卸妆时,只需擦拭2次再配合洗面奶或清水清洗,即可将眼部化妆品清洗干净,而且无刺激性,而使用普通卸妆湿巾时,需要使用3-4片湿巾,才可擦拭干净,而且由于湿巾中的防腐剂,会刺激眼部流泪。When using the eye makeup remover dry wipes of this embodiment to remove eye makeup, you only need to wipe twice and rinse with facial cleanser or water to clean the eye makeup without irritation. When using ordinary makeup remover wipes , You need to use 3-4 wet wipes to wipe clean, and because of the preservatives in the wipes, it will irritate the eyes to tear.
实施例8Example 8
一种干巾,包括基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.05ml/cm 2的水接触,所述冻干膜层可在4s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述基布载体层的形状为圆形无纺布,材质为天丝与铜氨混纺无纺布,所述冻干膜层的厚度为10μm。所述冻干膜层只包括冻干功效物,所述冻干功效物为表皮生长因子。 A dry towel, comprising a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form, the dry towel is in contact with 0.05 ml/cm 2 of water, the freeze-dried film layer It can be dissolved within 4s, and the dissolution rate of the lyophilized product can reach more than 90% within 1 min. The shape of the base fabric carrier layer is a circular non-woven fabric, and the material is a tencel and cupr ammonia blended non-woven fabric, and the thickness of the freeze-dried film layer is 10 μm. The freeze-dried film layer only includes freeze-dried functional substances, and the freeze-dried functional substances are epidermal growth factor.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将表皮生长因子6mg加水(至400ml)溶解后,喷洒于天丝与铜氨的混纺基布表面,-50℃~-30℃真空冷冻干燥;Step 1: Dissolve 6mg of epidermal growth factor with water (to 400ml), spray it on the surface of the blended base fabric of Tencel and cupra, and freeze-dry under vacuum at -50℃~-30℃;
步骤2:包装成分皮肤愈合敷料干巾。Step 2: Pack the ingredients of the skin healing dressing dry towel.
本实施例中的干巾作为敷料干巾使用。使用时,可直接与皮肤表面的伤口渗出液接触,或喷洒少量无菌水,使冻干膜层溶解或溶出,然后在与表皮发生摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜,起到皮肤护理、促进愈合的作用。The dry towel in this embodiment is used as a dressing dry towel. When in use, it can directly contact the wound exudate on the skin surface, or spray a small amount of sterile water to dissolve or dissolve the freeze-dried film layer, and then when rubbing with the epidermis, the freeze-dried film layer and the base cloth carrier layer Peeling, forming a film on the epidermis, playing a role in skin care and promoting healing.
利用本实施例的敷料干巾时,在伤口擦拭两次即可,伤口与外界环境隔离,伤口愈合时间为10h左右,而使用含有表皮生长因子的液体创口贴,伤口愈合时间为24h左右。When using the dressing dry towel of this embodiment, the wound can be wiped twice, and the wound is isolated from the external environment, and the wound healing time is about 10 hours, while the liquid wound patch containing epidermal growth factor is used, and the wound healing time is about 24 hours.
实施例9Example 9
一种干巾,包括基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.005ml/cm 2的水接触,所述冻干膜层可在4s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述基布载体层的形状为方形无纺布,材质为纯棉与天丝的混纺,所述冻干膜层的厚度为2μm。所述冻干膜层包括冻干功效物和冻干纤维,所述冻干功效物为水杨酸、木瓜蛋白酶,所述冻干纤维为胶原蛋白纤维。 A dry towel, comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel is in contact with 0.005 ml/cm 2 of water, the freeze-dried film layer It can be dissolved within 4s, and the dissolution rate of the lyophilized product can reach more than 90% within 1 min. The shape of the base fabric carrier layer is a square non-woven fabric, and the material is a blend of pure cotton and tencel, and the thickness of the freeze-dried film layer is 2 μm. The freeze-dried film layer includes freeze-dried functional substances and freeze-dried fibers, the freeze-dried functional substances are salicylic acid and papain, and the freeze-dried fibers are collagen fibers.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将水杨酸0.1%、木瓜蛋白酶1%加水(至100%)溶解,以200-300g/㎡的比例喷洒在28g/㎡的胶原蛋白纤维表面,-50℃~-30℃真空冷冻干燥;Step 1: Dissolve 0.1% salicylic acid and 1% papain in water (to 100%), spray it on the surface of 28g/㎡ collagen fiber at a ratio of 200-300g/㎡, and freeze under vacuum at -50℃~-30℃ dry;
步骤2:冻干膜与纯棉与天丝的混纺基布复合,形成角质软化干巾。Step 2: The freeze-dried film is combined with the blended base fabric of pure cotton and Tencel to form a dry cuticle softening towel.
本实施例中的干巾作为角质软化干巾使用。使用时,首先将所述干巾与水接触,冻干膜层溶解或溶出,然后在与表皮发生摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜,软化角质,达到皮肤提亮的效果。The dry towel in this embodiment is used as a cuticle softening dry towel. When in use, first contact the dry towel with water to dissolve or dissolve the lyophilized film layer, and then when rubbing against the epidermis, the lyophilized film layer is peeled off from the carrier layer of the base fabric, forming a film on the epidermis, and softening the cuticle , To achieve the effect of skin brightening.
在本实施例的基础上,对成分含量做如下调整:水杨酸0.5%、木瓜蛋白酶0.5%加水(至100%)溶解,将得到的100ml溶液,喷洒1m 2在100g/㎡的胶原蛋白纤维表面; On the basis of this example, the content of the ingredients is adjusted as follows: 0.5% salicylic acid, 0.5% papain and water (to 100%) to dissolve, and the obtained 100ml solution is sprayed with 1m 2 of collagen fiber at 100g/㎡ surface;
或水杨酸0.5%、木瓜蛋白酶0.5%加水(至100%)溶解,将得到的10000ml溶液,喷洒1m 2在0.4g/㎡的胶原蛋白纤维表面; Or dissolve with 0.5% salicylic acid and 0.5% papain with water (to 100%), and spray 1m 2 of the 0.4g/㎡ collagen fiber surface with the obtained 10000ml solution;
或水杨酸0.5%、木瓜蛋白酶0.5%加水(至100%)溶解,将得到的100ml溶液,喷洒1m 2在0.4g/㎡的胶原蛋白纤维表面;都得到效果相同的角质软化干巾。 Salicylic acid or 0.5%, 0.5% papain was added water (100%) was dissolved, and the resulting solution was 100ml, sprayed in 2 0.4g / collagen 1m square meters of fiber surface; get the same effect to soften the skin dry towel.
对比例9Comparative example 9
软化角质湿巾棉片(品牌:春雨,市售):其配方中水,甲基丙二醇(刺激性)、1,2己二醇(防腐)、PEG/PPG-17-6共聚物、酒精(刺激性)、桦木汁、乳酸(刺激性)、羟基乙酸(刺激性)、二丙二醇(防腐)、茄子果提取物、透明质酸钠、水杨酸(刺激性)、甘草根提取物、乙基己二醇、葡萄果提取物、苹果提取物、柠檬果提取物、苦橙提取物、柑橘提取物、积雪草提取物、茶叶提取物、川梀叶提取物,金盏花叶提取物、PEG-60氢化蓖麻油、苯并三唑基丁苯酚磺酸钠(防晒剂)、聚甘油醚-26、丁醇聚醚-3(刺激性)、柠檬酸三丁酯(刺激性)、海藻糖、甜菜碱、尿囊素、栀子果提取物、氨丁三醇、糊精、EDTA二钠、丁二醇、 聚山梨酸酯-20、柠檬酸、丙烯酰二甲基/VP共聚物、辛酸甘油酯、乙基己基甘油。该湿巾面片在软化角质的同时有较强刺激性,对皮肤的安全风险隐患较大。Cuticle softening wet wipes (brand: Chunyu, commercially available): its formula contains water, methyl propylene glycol (irritant), 1,2 hexanediol (anticorrosive), PEG/PPG-17-6 copolymer, alcohol ( Irritant), birch juice, lactic acid (irritant), glycolic acid (irritant), dipropylene glycol (preservative), eggplant fruit extract, sodium hyaluronate, salicylic acid (irritant), licorice root extract, ethyl Hexanediol, grape fruit extract, apple extract, lemon fruit extract, bitter orange extract, citrus extract, Centella asiatica extract, tea extract, Chuanmu leaf extract, Calendula leaf extract , PEG-60 hydrogenated castor oil, sodium benzotriazolyl butyl phenol sulfonate (sunscreen agent), polyglycerol ether-26, buteth-3 (irritant), tributyl citrate (irritant), Trehalose, betaine, allantoin, gardenia fruit extract, tromethamine, dextrin, disodium EDTA, butylene glycol, polysorbate-20, citric acid, acryldimethyl/VP copolymer Materials, caprylic acid glyceride, ethylhexyl glycerol. The wet tissue face sheet has strong irritation while softening the keratin, and has a greater potential safety risk to the skin.
实施例10Example 10
一种干巾,包括双层离型层、基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.08ml/cm 2的水接触,所述冻干膜层可在8s内溶解,检测1min内冻干功效物溶出度达到90%以上。所述基布载体层的形状为方形无纺布,材质为普通无纺布,所述离型层的性状与基布载体层一致,双层材质各为bopp和铝箔,所述冻干膜层的厚度为150μm。所述冻干膜层包含冻干功效物、冻干肤感剂和冻干纤维,所述冻干功效物为神经酰胺、炉甘石、氧化锌,所述冻干肤感剂为丙二醇、甘油,所述冻干纤维为海藻纤维。 A dry towel comprising a double-layer release layer, a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form, the dry towel being in contact with 0.08 ml/cm 2 of water, The freeze-dried film layer can be dissolved within 8 seconds, and the dissolution rate of the freeze-dried functional substance reaches more than 90% within 1 min. The shape of the base fabric carrier layer is a square non-woven fabric, and the material is ordinary non-woven fabric. The properties of the release layer are consistent with the base fabric carrier layer. The two-layer materials are each bopp and aluminum foil. The freeze-dried film layer The thickness is 150μm. The freeze-dried film layer comprises a freeze-dried functional substance, a freeze-dried skin feel agent and a freeze-dried fiber, the freeze-dried functional substance is ceramide, calamine, zinc oxide, and the freeze-dried skin feel agent is propylene glycol, glycerin The freeze-dried fiber is seaweed fiber.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将神经酰胺0.1%、炉甘石2%、氧化锌1%、丙二醇2%、甘油15%溶于水(至100%),喷洒于海藻纤维表面,-50℃-25℃真空冷冻干燥;Step 1: Dissolve ceramide 0.1%, calamine 2%, zinc oxide 1%, propylene glycol 2%, and glycerin 15% in water (to 100%), spray on the surface of the seaweed fiber, and freeze in vacuum at -50℃-25℃ dry;
步骤2:上述冻干膜层与无纺布基布复合;Step 2: The above freeze-dried film layer is compounded with the non-woven fabric base fabric;
步骤3:与双层离型层复合形成终产品。Step 3: Compound with the double-layer release layer to form the final product.
本实施例中的干巾作为皮疹外用药护理干巾使用。使用时,干巾在与创伤口发生接触时,渗出的创伤组织液即可促进冻干膜层溶解或溶出,然后在与表皮发生摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜,去痒消肿,起到辅助治疗的作用。The dry towel in this embodiment is used as a dry towel for external rash care. In use, when the dry towel comes into contact with the wound, the exuded wound tissue fluid can promote the dissolution or dissolution of the freeze-dried film layer, and then when rubbing with the epidermis, the freeze-dried film layer is peeled from the base cloth carrier layer, It forms a film on the epidermis to eliminate itching and swelling, and play an adjuvant therapy role.
本实施例的外用药护理干巾擦拭完成后,即可起到效果,保证皮肤干爽,而涂抹液体或膏状的药品后,不利于皮疹的恢复。After wiping with the external medicine care dry towel of this embodiment, it can be effective to ensure dry skin. However, after applying liquid or paste medicine, it is not conducive to the recovery of the rash.
实施例11Example 11
一种干巾,包括离型层、基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.03ml/cm 2的水接触,所述冻干膜层可在6s内溶解。所述基布载体层的形状为不规则形,材质为无纺布,所述离型层与基布载体层的性状一致,材质为pu,所述冻干膜层的厚度为15μm。所述冻干膜层包含冻干肤感剂,所述冻干肤感剂为黄原胶、银耳多糖。 A dry towel, comprising a release layer, a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form. The dry towel is in contact with 0.03 ml/cm 2 of water, and the The lyophilized film can be dissolved in 6s. The shape of the base fabric carrier layer is irregular, the material is non-woven fabric, the release layer has the same properties as the base fabric carrier layer, the material is pu, and the thickness of the freeze-dried film layer is 15 μm. The freeze-dried film layer contains a freeze-dried skin feel agent, and the freeze-dried skin feel agent is xanthan gum and tremella polysaccharide.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将黄原胶0.2%、银耳多糖0.3%加水(至100%)溶解,涂布于基布表面,-50℃-30℃冷冻干燥;Step 1: Dissolve 0.2% xanthan gum and 0.3% Tremella polysaccharide with water (to 100%), apply on the surface of the base cloth, and freeze-dry at -50℃-30℃;
步骤2:与离型层复合形成终产品。Step 2: Compound with the release layer to form the final product.
本实施例中的干巾作为保湿精华干巾使用。使用时,首先将所述干巾与水接触,冻干膜层溶解或溶出,然后在与表皮发生摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜,起到保湿润肤的作用。The dry towel in this embodiment is used as a moisturizing essence dry towel. When in use, the dry towel is first contacted with water to dissolve or dissolve the freeze-dried film layer, and then when rubbing against the epidermis, the freeze-dried film layer is peeled off from the base fabric carrier layer to form a film on the epidermis. The role of moisturizing and emollient.
本实施例的保湿精华干巾擦拭3次,10s后皮肤含水量可达到49%,市售普通湿巾,一 般需要湿敷10-15min,皮肤含水量才可达到45%。The moisturizing essence dry wipes of this example are wiped 3 times, and the skin moisture content can reach 49% after 10 seconds. Common commercially available wipes generally need to be wet for 10-15 minutes before the skin moisture content can reach 45%.
实施例12Example 12
一种干巾,包括离型层、基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.0015ml/cm 2的水接触,所述冻干膜层可在7s内溶解。所述基布载体层的形状为长方形,材质为竹纤维,所述离型层形状与基布载体层一致,材质为PVC,所述冻干膜层的厚度为25μm。所述冻干膜层为冻干纤维,所述冻干纤维为藻酸盐纤维。 A dry towel, comprising a release layer, a base fabric carrier layer and a freeze-dried film layer attached to the base fabric carrier layer in a freeze-dried form. The dry towel is in contact with 0.0015 ml/cm 2 of water, and the The lyophilized film can be dissolved in 7 seconds. The shape of the base fabric carrier layer is rectangular, the material is bamboo fiber, the shape of the release layer is consistent with the base fabric carrier layer, the material is PVC, and the thickness of the freeze-dried film layer is 25 μm. The freeze-dried film layer is freeze-dried fiber, and the freeze-dried fiber is alginate fiber.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将藻酸盐纤维加入0.2%柠檬酸钠溶液,-50℃~-30℃冷冻干燥后,与基布进行复合;Step 1: Add the alginate fiber to 0.2% sodium citrate solution, freeze-dried at -50°C to -30°C, and composite with the base cloth;
步骤2:与离型层复合形成终产品。Step 2: Compound with the release layer to form the final product.
本实施例中的干巾适合婴儿干湿巾使用。使用时,首先将所述干巾与0.0015ml/cm 2水接触,依靠皮肤本身水分或空气中的水分,冻干膜层也可以在7s内完成溶解或溶出,然后在与表皮发生摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜,起到保湿、润肤的作用。 The dry wipes in this embodiment are suitable for baby wet wipes. When in use, first contact the dry towel with 0.0015ml/cm 2 of water. Depending on the moisture of the skin or the moisture in the air, the freeze-dried film layer can also be dissolved or dissolved within 7 seconds, and then when friction occurs with the epidermis, The freeze-dried film layer is peeled from the carrier layer of the base cloth to form a film on the epidermis to play a role of moisturizing and emollient.
对比例12Comparative example 12
一种婴儿湿巾,包含2%海藻酸钠、0.1%戊二醇、水(至100%)。使用时直接擦拭,但由于含有戊二醇在高频使用后,对婴儿表皮菌群产生影响,抑制表皮菌群生长(抑制率30%),对婴儿皮肤健康产生影响。A baby wipes containing 2% sodium alginate, 0.1% pentanediol, water (to 100%). Wipe it directly when used, but because it contains pentanediol after high frequency use, it will affect the epidermal flora of the baby, inhibit the growth of the epidermal flora (inhibition rate of 30%), and affect the health of the baby's skin.
实施例13Example 13
一种干巾,包括基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,所述干巾与0.02ml/cm 2的水接触,所述冻干膜层可在5s内溶解。所述基布载体层的形状为不规则形,材质为无纺布,所述冻干膜层的厚度为2.5μm。所述冻干膜层包含冻干肤感剂和冻干纤维,所述冻干肤感剂为糖类同分异构体、辛甘醇和聚丙烯酸钠,所述冻干纤维为海藻纤维。 A dry towel, comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, the dry towel is in contact with 0.02 ml/cm 2 of water, the freeze-dried film layer It can be dissolved within 5s. The shape of the base fabric carrier layer is irregular, the material is non-woven fabric, and the thickness of the freeze-dried film layer is 2.5 μm. The freeze-dried film layer comprises a freeze-dried skin feel agent and freeze-dried fiber, the freeze-dried skin feel agent is sugar isomers, octyl glycol and sodium polyacrylate, and the freeze-dried fiber is seaweed fiber.
所述干巾通过以下方法加工:The dry towel is processed by the following method:
步骤1:将糖类同分异构体1.5%、辛甘醇5%、聚丙烯酸钠0.2%加水(至100%)溶解,以15-35g/㎡的比例涂布于65g/㎡的海藻纤维表面,-50℃-30℃冷冻干燥,形成冻干膜;Step 1: Dissolve carbohydrate isomer 1.5%, octylene glycol 5%, sodium polyacrylate 0.2% with water (to 100%), and apply 15-35g/㎡ to 65g/㎡ seaweed fiber The surface is freeze-dried at -50℃-30℃ to form a freeze-dried film;
步骤2:上述冻干膜与载体层复合形成终产品。Step 2: The freeze-dried film and the carrier layer are compounded to form the final product.
本实施例中的干巾作为保湿精华干巾使用。使用时,首先将所述干巾与0.02ml/cm 2的水接触,冻干膜层在5s内溶解或溶出,然后在表皮擦拭,所述冻干膜层与基布载体层剥离,在表皮上成膜,起到保湿润肤的作用。 The dry towel in this embodiment is used as a moisturizing essence dry towel. In use, the towel dry the water contact 0.02ml / cm 2 and the lyophilized film was dissolved within 5s or dissolution, and then wipe the skin, the lyophilized carrier base fabric layer delamination in the epidermis It forms a film on the top to play the role of moisturizing and emollient.
本实施例的保湿精华干巾擦拭2次,15s后皮肤含水量可达到50%,市售普通湿巾,一 般需要湿敷10-15min,皮肤含水量才可达到40%。The moisturizing essence dry wipes of this example are wiped twice, and the skin moisture content can reach 50% after 15 seconds. Common commercially available wipes generally require 10-15 minutes of wet dressing before the skin moisture content can reach 40%.
在本实施例的基础上,对个组分含量做出如下调整:On the basis of this embodiment, the following adjustments are made to the content of each component:
步骤1:将糖类同分异构体0.8%、辛甘醇0.1%、聚丙烯酸钠0.1%加水(至100%)溶解,取100ml,的比例涂布于0.2g/㎡的海藻纤维表面,-50℃-30℃冷冻干燥,形成冻干膜;Step 1: Dissolve sugar isomer 0.8%, octyl glycol 0.1%, sodium polyacrylate 0.1% with water (to 100%), take 100ml, and apply the ratio on the surface of 0.2g/㎡ seaweed fiber. Freeze drying at -50℃-30℃ to form a lyophilized film;
或步骤1:将糖类同分异构体0.8%、辛甘醇0.1%、聚丙烯酸钠0.1%加水(至100%)溶解,取100ml,的比例涂布于1000g/㎡的海藻纤维表面,-50℃-30℃冷冻干燥,形成冻干膜;Or step 1: Dissolve sugar isomer 0.8%, octyl glycol 0.1%, sodium polyacrylate 0.1% with water (to 100%), take 100ml, and apply the ratio on the surface of 1000g/㎡ seaweed fiber. Freeze drying at -50℃-30℃ to form a lyophilized film;
或步骤1:将糖类同分异构体0.8%、辛甘醇0.1%、聚丙烯酸钠0.1%加水(至100%)溶解,取10000ml,的比例涂布于0.2g/㎡的海藻纤维表面,-50℃-30℃冷冻干燥,形成冻干膜;Or step 1: Dissolve sugar isomer 0.8%, octylene glycol 0.1%, sodium polyacrylate 0.1% with water (to 100%), take 10000ml, and apply the ratio on the surface of 0.2g/㎡ seaweed fiber , Freeze dried at -50℃-30℃ to form a lyophilized film;
以上各组分的调整均得到与实施例13相同效果的保湿精华干巾。The adjustment of the above components all obtain the moisturizing essence dry towel with the same effect as in Example 13.
以上所述仅是本发明的优选实施方式,应当指出的是,对于本技术领域的普通技术人员来说,在不脱离本发明原理的前提下,还可以做出若干改进和润饰,这些改进和润饰也应视为本发明的保护范围。The above are only the preferred embodiments of the present invention. It should be pointed out that for those of ordinary skill in the art, without departing from the principle of the present invention, several improvements and modifications can be made. These improvements and Retouching should also be regarded as the protection scope of the present invention.

Claims (22)

  1. 一种干巾,包括基布载体层和以冷冻干燥形式附着在所述基布载体层上的冻干膜层,其特征在于,所述基布载体层和冻干膜层与0.0001ml/cm 2-0.1ml/cm 2的水接触,所述冻干膜层即可溶解或溶出。 A dry towel, comprising a base cloth carrier layer and a freeze-dried film layer attached to the base cloth carrier layer in a freeze-dried form, characterized in that the base cloth carrier layer and the freeze-dried film layer have a ratio of 0.0001 ml/cm 2 -0.1ml/cm 2 of water contact, the freeze-dried film can be dissolved or dissolved.
  2. 如权利要求1所述的干巾,其特征在于,所述冻干膜层溶解或溶出的时间为3-10s。The dry towel according to claim 1, wherein the dissolution or dissolution time of the freeze-dried film layer is 3-10 seconds.
  3. 如权利要求1所述的干巾,其特征在于,所述冻干膜层的厚度为0.1μm-300μm。The dry towel according to claim 1, wherein the thickness of the freeze-dried film layer is 0.1 μm-300 μm.
  4. 如权利要求1所述的干巾,其特征在于,所述干巾还包括离型层。8. The dry towel of claim 1, wherein the dry towel further comprises a release layer.
  5. 如权利要求4所述的干巾,其特征在于,所述离型层为一层或两层,所述离型层位于所述基布载体层的冻干膜层的一侧或两侧。The dry towel according to claim 4, wherein the release layer is one or two layers, and the release layer is located on one or both sides of the freeze-dried film layer of the base fabric carrier layer.
  6. 如权利要求4所述的干巾,其特征在于,所述离型层为pet、pe、pu、bopp、pvc、pp、铝箔中的一种或组合。The dry towel of claim 4, wherein the release layer is one or a combination of pet, pe, pu, bopp, pvc, pp, and aluminum foil.
  7. 如权利要求1所述的干巾,其特征在于,所述基布载体层为无纺布、脱脂棉、棉纤维、竹纤维、海藻纤维、天丝、铜氨、莫代尔纤维中的一种或多种混纺。The dry towel according to claim 1, wherein the base fabric carrier layer is one or more of non-woven fabric, absorbent cotton, cotton fiber, bamboo fiber, seaweed fiber, tencel, cupra, modal fiber Kind of blending.
  8. 如权利要求1所述的干巾,其特征在于,所述冻干膜层包括冻干功效物、冻干肤感剂或冻干纤维中的一种或组合。The dry towel according to claim 1, wherein the freeze-dried film layer comprises one or a combination of freeze-dried efficacy substance, freeze-dried skin feel agent or freeze-dried fiber.
  9. 如权利要求8所述的干巾,其特征在于,当所述冻干膜层包括冻干功效物、冻干肤感剂和冻干纤维时,其中,所述冻干功效物、冻干肤感剂和冻干纤维的质量比为(1-30):(0.1-50):(0.1-100);The dry towel according to claim 8, wherein when the freeze-dried film layer includes a freeze-dried functional substance, a freeze-dried skin feel agent and a freeze-dried fiber, wherein the freeze-dried functional substance, the freeze-dried skin The mass ratio of sensitizer and freeze-dried fiber is (1-30): (0.1-50): (0.1-100);
    当所述冻干膜层包括冻干功效物和冻干肤感剂时,所述冻干功效物和冻干肤感剂的质量比为(1-30):(0.1-30);When the freeze-dried film layer includes a freeze-dried functional substance and a freeze-dried skin feel agent, the mass ratio of the freeze-dried functional substance and the freeze-dried skin feel agent is (1-30): (0.1-30);
    当所述冻干膜层包括冻干功效物和和冻干纤维时,所述冻干功效物和冻干纤维的质量比为(1-100):(0.4-100);When the freeze-dried film layer includes freeze-dried functional substances and freeze-dried fibers, the mass ratio of the freeze-dried functional substances and freeze-dried fibers is (1-100): (0.4-100);
    当所述冻干膜层包括冻干肤感剂和冻干纤维时,所述冻干肤感剂和冻干纤维的质量比为(1-100):(0.2-1000)。When the freeze-dried film layer includes the freeze-dried skin feel agent and the freeze-dried fiber, the mass ratio of the freeze-dried skin feel agent and the freeze-dried fiber is (1-100): (0.2-1000).
  10. 如权利要求8所述的干巾,其特征在于,所述冻干功效物选自西药成分、中药成分、天然提取物、生物活性成分、皮肤护理有益成分中的一种或组合,所述冻干肤感剂选自蛋白类、多糖及其盐类、高分子聚合物类、多元醇类、天然及合成油脂类、表面活性剂类中的一种或组合,所述冻干纤维为胶原蛋白纤维、壳聚糖纤维、海藻盐纤维、藻壳共混纤维、羧甲基纤维素纤维中的一种或组合。The dry towel according to claim 8, wherein the freeze-dried effect is selected from one or a combination of western medicine ingredients, traditional Chinese medicine ingredients, natural extracts, biologically active ingredients, and skin care beneficial ingredients. The dry skin feel agent is selected from one or a combination of proteins, polysaccharides and their salts, high molecular polymers, polyols, natural and synthetic oils, and surfactants, and the freeze-dried fiber is collagen One or a combination of fiber, chitosan fiber, seaweed salt fiber, algae shell blend fiber, carboxymethyl cellulose fiber.
  11. 如权利要求10所述的干巾,其特征在于,所述冻干功效物中的西药成分为酮洛芬、布洛芬、萘甲唑啉、双氯芬酸二乙胺、酮康唑、氢化可的松、咪康唑氯倍他索、曲咪新、间苯二酚,所述中药成分为冰片、薄荷、樟脑、甘草、黄芩、姜黄、大黄、硫磺、苦参、蛇床子、黄连、黄柏、炉甘石、氧化锌,所述天然提取物为橙皮苷提取物、加拿大红枫提取物、 黄芩根提取物、无患子提取物、脂肪酸酰胺烷基甜菜碱、积雪草提取物、针叶樱桃提取物、芍药根提取物、莲花提取物、雪莲提取物、人参根提取物、黄瓜果提取、芦荟叶提取物、马齿苋提取物、甘牛至叶提取物、接骨木提取物、玫瑰提取物、海藻提取物、松露提取物、冬虫夏草提取物、西红花提取物、银耳提取物、当归提取物、五味子提取物、母菊花提取物、山茶花提取物、白术提取物、三七提取物、姜根提取物、白芨提取物、白鲜皮提取物、薰衣草提取物、白蒺藜提取物或霍霍巴叶提取物,所述生物活性成分为表皮生长因子、寡肽-1、芽孢杆菌发酵产物、乙酰基四肽-2、乙酰基六肽-1、棕榈酰三肽、铜肽、肌肽、氨基丁酸或木瓜蛋白酶,所述皮肤护理成分为橙皮苷、牛奶蛋白、乙酰基六肽-1、芽孢杆菌发酵产物、月桂酰谷氨酸钠、乙酰化透明质酸钠、神经酰胺、椰油基甜菜碱、水杨酸、乳酸、羟基乙酸、谷胱甘肽、SOD、辅酶Q10、烟酰胺、生育酚及衍生物、视黄醇及衍生物、抗坏血酸及衍生物、海藻糖、糖类同分异构体、角鲨烷、乳木果油、阿魏酸、胶原蛋白、甘油葡糖苷、咖啡因、四氢甲基嘧啶羧酸、红没药醇、水飞蓟素、白藜芦醇、植物甾醇或虾青素;The dry towel of claim 10, wherein the western medicine ingredients in the freeze-dried product are ketoprofen, ibuprofen, naphazoline, diclofenac diethylamine, ketoconazole, hydrocortisone Pine, miconazole, clobetasol, trichomidine, resorcinol, and the traditional Chinese medicine ingredients are borneol, peppermint, camphor, licorice, scutellaria, turmeric, rhubarb, sulfur, sophora flavescens, cranberry, coptis, cork, Calamine, zinc oxide, the natural extracts are hesperidin extract, Canadian red maple extract, scutellaria root extract, Sapindus extract, fatty acid amide alkyl betaine, Centella asiatica extract, needle Leaf cherry extract, peony root extract, lotus extract, snow lotus extract, ginseng root extract, cucumber fruit extract, aloe leaf extract, portulaca extract, sweet oregano leaf extract, elderberry extract , Rose Extract, Seaweed Extract, Truffle Extract, Cordyceps Extract, Saffron Extract, Tremella Extract, Angelica Extract, Schisandra Extract, Matricaria Flower Extract, Camellia Extract, Atractylodes Rhizome Extract, Panax Notoginseng Extract, ginger root extract, Bletilla striata extract, white fresh bark extract, lavender extract, Tribulus terrestris extract or jojoba leaf extract, the biologically active ingredients are epidermal growth factor, oligopeptide-1, Bacillus Fermentation product, acetyl tetrapeptide-2, acetyl hexapeptide-1, palmitoyl tripeptide, copper peptide, carnosine, aminobutyric acid or papain, the skin care ingredients are hesperidin, milk protein, acetyl hexapeptide Peptide-1, Bacillus fermentation product, sodium lauroyl glutamate, sodium acetylated hyaluronate, ceramide, cocobetaine, salicylic acid, lactic acid, glycolic acid, glutathione, SOD, coenzyme Q10 , Niacinamide, tocopherol and derivatives, retinol and derivatives, ascorbic acid and derivatives, trehalose, carbohydrate isomers, squalane, shea butter, ferulic acid, collagen, glycerin Glucoside, caffeine, tetrahydromethylpyrimidine carboxylic acid, bisabolol, silymarin, resveratrol, phytosterol or astaxanthin;
    所述冻干肤感剂中的蛋白类为可溶性糖蛋白、胶原蛋白或水解明胶,所述多糖为果聚糖、黄原胶、透明质酸钠、聚谷氨酸、糖类同分异构体、银耳多糖或海藻糖,所述多元醇为丙二醇、甘油、丁二醇或辛甘醇,所述天然及合成油脂类为矿脂、油醇,辛酸/癸酸甘油三酯或氢化棕榈油,所述高分子聚合物类为聚丙烯酸钠或卡波姆,所述表面活性剂为聚甘油-10甘油酯、聚甘油-10-硬脂酸酯、聚山梨醇酯80、椰油基甜菜碱、月桂酰谷氨酸钠或脂肪酸酰胺烷基甜菜碱。The protein in the freeze-dried skin feel agent is soluble glycoprotein, collagen or hydrolyzed gelatin, and the polysaccharide is fructan, xanthan gum, sodium hyaluronate, polyglutamic acid, and carbohydrate isomers Body, tremella polysaccharide or trehalose, the polyol is propylene glycol, glycerin, butylene glycol or caprylyl, the natural and synthetic oils are petrolatum, oleyl alcohol, caprylic/capric triglyceride or hydrogenated palm oil , The high molecular polymer is sodium polyacrylate or carbomer, and the surfactant is polyglycerol-10 glyceride, polyglycerol-10-stearate, polysorbate 80, coco-beet Alkali, sodium lauroyl glutamate or fatty acid amide alkyl betaine.
  12. 如权利要求8-11中任一项所述的干巾,其特征在于,通过以下方法加工:The dry towel according to any one of claims 8-11, characterized in that it is processed by the following method:
    步骤1:将冻干功效物溶解或分散于冻干肤感剂中;Step 1: Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent;
    步骤2:将冻干功效物与冻干肤感剂的混合物加温熔融至具有流动性;Step 2: The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
    步骤3:涂布于基布表面,-50℃~-30℃冷冻干燥;Step 3: Coat on the surface of the base cloth, freeze-dry at -50℃~-30℃;
    或者通过以下方法加工:Or process by the following methods:
    步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒在冻干纤维表面或与冻干纤维相互浸润,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
    步骤2:冻干膜与基布复合;Step 2: The freeze-dried film is combined with the base fabric;
    或者通过以下方法加工:Or process by the following methods:
    步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒于基布表面,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the base fabric, and freeze-dry at -50°C to -30°C;
    步骤2:与离型层复合形成终产品;Step 2: Compound with the release layer to form the final product;
    或者通过以下方法加工:Or process by the following methods:
    步骤1:将冻干纤维加水或水溶液,-50℃~-30℃冷冻干燥后,与基布进行混纺复合;Step 1: Add water or aqueous solution to the freeze-dried fiber, freeze-dried at -50°C to -30°C, and blend and compound with the base fabric;
    步骤2:与离型层复合形成终产品。Step 2: Compound with the release layer to form the final product.
  13. 权利要求1-11中任一项所述干巾,其特征在于,所述干巾与水接触,冻干膜层溶解或溶出,然后在与表皮发生接触或摩擦时,所述冻干膜层与基布载体层剥离,在表皮上成膜。The dry towel according to any one of claims 1-11, wherein the dry towel is in contact with water, the freeze-dried film layer is dissolved or dissolved, and then when contact or friction occurs with the epidermis, the freeze-dried film layer Peel off from the carrier layer of the base cloth and form a film on the epidermis.
  14. 权利要求1-11中任一项所述干巾作为护肤用品、卸妆清洁用品、透皮吸收外用药贴片或创面敷料贴片的应用。The use of the dry towel as claimed in any one of claims 1-11 as a skin care product, a makeup remover cleaning product, a transdermal absorption external medicine patch or a wound dressing patch.
  15. 内含如权利要求1-11中任一项所述干巾的包装。A package containing the dry towel according to any one of claims 1-11.
  16. 一种以冻干形式形成在基布载体层上的冻干膜层,其特征在于,所述冻干膜层包括冻干功效物和/或冻干肤感剂和/或冻干纤维组成分,其中,所述冻干功效物选自西药成分、中药成分、天然提取物、生物活性成分、皮肤护理有益成分中的一种或组合,所述冻干肤感剂选自蛋白类、多糖及其盐类、高分子聚合物类、多元醇类、天然及合成油脂类、表面活性剂类中的一种或组合,所述冻干纤维为胶原蛋白纤维、壳聚糖纤维、海藻盐纤维、藻壳共混纤维、羧甲基纤维素纤维中的一种或组合。A freeze-dried film layer formed on a base fabric carrier layer in a freeze-dried form, wherein the freeze-dried film layer includes a freeze-dried functional substance and/or a freeze-dried skin feel agent and/or a freeze-dried fiber component , Wherein the freeze-dried effect is selected from one or a combination of western medicine ingredients, traditional Chinese medicine ingredients, natural extracts, biologically active ingredients, and skin care beneficial ingredients, and the freeze-dried skin feel agent is selected from proteins, polysaccharides and One or a combination of salts, high molecular polymers, polyols, natural and synthetic oils, and surfactants, and the freeze-dried fibers are collagen fibers, chitosan fibers, seaweed salt fibers, One or a combination of algae shell blend fibers and carboxymethyl cellulose fibers.
  17. 如权利要求16所述的冻干膜层,其特征在于,当所述冻干膜层包括冻干功效物、冻干肤感剂和冻干纤维时,其中,所述冻干功效物、冻干肤感剂和冻干纤维的质量比为(1-30):(0.1-50):(0.1-100);The freeze-dried film layer of claim 16, wherein when the freeze-dried film layer includes a freeze-dried functional substance, a freeze-dried skin feel agent and a freeze-dried fiber, wherein the freeze-dried functional substance, a freeze-dried fiber The mass ratio of dry skin feel agent and freeze-dried fiber is (1-30): (0.1-50): (0.1-100);
    当所述冻干膜层包括冻干功效物和冻干肤感剂时,所述冻干功效物和冻干肤感剂的质量比为(1-30):(0.1-30);When the freeze-dried film layer includes a freeze-dried functional substance and a freeze-dried skin feel agent, the mass ratio of the freeze-dried functional substance and the freeze-dried skin feel agent is (1-30): (0.1-30);
    当所述冻干膜层包括冻干功效物和和冻干纤维时,所述冻干功效物和冻干纤维的质量比为(1-100):(0.4-100);When the freeze-dried film layer includes freeze-dried functional substances and freeze-dried fibers, the mass ratio of the freeze-dried functional substances and freeze-dried fibers is (1-100): (0.4-100);
    当所述冻干膜层包括冻干肤感剂和冻干纤维时,所述冻干肤感剂和冻干纤维的质量比为(1-100):(0.2-1000)。When the freeze-dried film layer includes the freeze-dried skin feel agent and the freeze-dried fiber, the mass ratio of the freeze-dried skin feel agent and the freeze-dried fiber is (1-100): (0.2-1000).
  18. 如权利要求16所述的冻干膜层,其特征在于,所述冻干功效物中的西药成分为酮洛芬、布洛芬、萘甲唑啉、双氯芬酸二乙胺、酮康唑、氢化可的松、咪康唑氯倍他索、曲咪新、间苯二酚,所述中药成分为冰片、薄荷、樟脑、甘草、黄芩、姜黄、大黄、硫磺、苦参、蛇床子、黄连、黄柏、炉甘石、氧化锌,所述天然提取物为橙皮苷提取物、加拿大红枫提取物、黄芩根提取物、无患子提取物、脂肪酸酰胺烷基甜菜碱、积雪草提取物、针叶樱桃提取物、芍药根提取物、莲花提取物、雪莲提取物、人参根提取物、黄瓜果提取、芦荟叶提取物、马齿苋提取物、甘牛至叶提取物、接骨木提取物、玫瑰提取物、海藻提取物、松露提取物、冬虫夏草提取物、西红花提取物、银耳提取物、当归提取物、五味子提取物、母菊花提取物、山茶花提取物、白术提取物、三七提取物、姜根提取物、白芨提取物、白鲜皮提取物、薰衣草提取物、白蒺藜提取物或霍霍巴叶提取物,所述生物活性成分为表皮生长因子、寡肽-1、芽孢杆菌发酵产物、乙酰基四肽-2、乙酰基六肽-1、棕榈酰三肽、铜肽、肌肽、氨基丁酸或木瓜蛋白酶,所述皮肤护理成分为橙皮苷、牛奶蛋白、乙酰基六肽-1、芽孢杆菌发酵产物、月桂酰谷氨酸钠、乙酰化透明质酸钠、神经酰胺、椰油基甜菜碱、水杨酸、乳酸、羟基乙酸、谷胱甘肽、SOD、辅酶Q10、烟酰胺、生育酚及衍生物、视黄醇及衍生物、抗坏血酸及衍生物、海藻糖、糖类同分异构体、角鲨烷、乳木果油、阿魏酸、胶原蛋白、甘油葡糖苷、咖啡因、四氢甲基嘧啶羧酸、红没药醇、水飞蓟素、白藜芦醇、植物甾醇或虾青素;The freeze-dried film layer of claim 16, wherein the western medicine ingredients in the freeze-dried product are ketoprofen, ibuprofen, naphazoline, diclofenac diethylamine, ketoconazole, hydrogenated Cortisone, miconazole, clobetasol, trichomidine, resorcinol, and the traditional Chinese medicine ingredients are borneol, mint, camphor, licorice, scutellaria, turmeric, rhubarb, sulfur, sophora flavescens, cnidii, coptis, Phellodendron, calamine, zinc oxide, the natural extracts are hesperidin extract, Canadian red maple extract, scutellaria root extract, Sapindus extract, fatty acid amide alkyl betaine, Centella asiatica extract , Acerola cherry extract, peony root extract, lotus extract, snow lotus extract, ginseng root extract, cucumber fruit extract, aloe leaf extract, purslane extract, sweet oregano leaf extract, elderberry Extract, rose extract, seaweed extract, truffle extract, cordyceps extract, saffron extract, white fungus extract, angelica extract, schisandra extract, mother flower extract, camellia extract, atractylodes extract, Panax notoginseng extract, ginger root extract, Bletilla striata extract, white fresh bark extract, lavender extract, Tribulus terrestris extract or jojoba leaf extract, the biologically active ingredients are epidermal growth factor, oligopeptide-1, Bacillus fermentation product, acetyl tetrapeptide-2, acetyl hexapeptide-1, palmitoyl tripeptide, copper peptide, carnosine, aminobutyric acid or papain, the skin care ingredients are hesperidin, milk protein, acetyl Hexapeptide-1, Bacillus fermentation product, sodium lauroyl glutamate, sodium acetylated hyaluronate, ceramide, coco betaine, salicylic acid, lactic acid, glycolic acid, glutathione, SOD, Coenzyme Q10, nicotinamide, tocopherol and derivatives, retinol and derivatives, ascorbic acid and derivatives, trehalose, carbohydrate isomers, squalane, shea butter, ferulic acid, collagen , Glycerol glucoside, caffeine, tetrahydromethylpyrimidine carboxylic acid, bisabolol, silymarin, resveratrol, phytosterol or astaxanthin;
    所述冻干肤感剂中的蛋白类为可溶性糖蛋白、胶原蛋白或水解明胶,所述多糖为果聚糖、 黄原胶、透明质酸钠、聚谷氨酸、糖类同分异构体、银耳多糖或海藻糖,所述多元醇为丙二醇、甘油、丁二醇或辛甘醇,所述天然及合成油脂类为矿脂、油醇,辛酸/癸酸甘油三酯或氢化棕榈油,所述高分子聚合物类为聚丙烯酸钠、海藻酸钠或卡波姆,所述表面活性剂为聚甘油-10甘油酯、聚甘油-10-硬脂酸酯、聚山梨醇酯80、椰油基甜菜碱、月桂酰谷氨酸钠或脂肪酸酰胺烷基甜菜碱。The protein in the freeze-dried skin feel agent is soluble glycoprotein, collagen or hydrolyzed gelatin, and the polysaccharide is fructan, xanthan gum, sodium hyaluronate, polyglutamic acid, and carbohydrate isomers Body, tremella polysaccharide or trehalose, the polyol is propylene glycol, glycerin, butylene glycol or caprylyl, the natural and synthetic oils are petrolatum, oleyl alcohol, caprylic/capric triglyceride or hydrogenated palm oil The high molecular polymer is sodium polyacrylate, sodium alginate or carbomer, and the surfactant is polyglycerol-10 glyceride, polyglycerol-10-stearate, polysorbate 80, Coco betaine, sodium lauroyl glutamate or fatty acid amide alkyl betaine.
  19. 如权利要求16-18任一项所述的冻干膜层,其特征在于,通过以下步骤制备:The freeze-dried film layer according to any one of claims 16-18, which is prepared by the following steps:
    步骤1:将冻干功效物溶解或分散于冻干肤感剂中;Step 1: Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent;
    步骤2:将冻干功效物与冻干肤感剂的混合物加温熔融至具有流动性;Step 2: The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
    步骤3:-50℃~-30℃冷冻干燥;Step 3: Freeze drying at -50℃~-30℃;
    或者通过以下方法加工:Or process by the following methods:
    步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒在冻干纤维表面或与冻干纤维相互浸润,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
    或者通过以下方法加工:Or process by the following methods:
    步骤1:将冻干功效物溶解或分散于冻干肤感剂中;Step 1: Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent;
    步骤2:将冻干功效物与冻干肤感剂的混合物加温熔融至具有流动性;Step 2: The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
    步骤3:将上述混合物喷洒在冻干纤维表面或与冻干纤维相互浸润,-50℃~-30℃冷冻干燥;Step 3: Spray the above mixture on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
    或者通过以下方法加工:Or process by the following methods:
    步骤1:将冻干纤维加水或水溶液,-50℃~-30℃冷冻干燥。Step 1: Add water or aqueous solution to the freeze-dried fiber, freeze-dry it at -50°C to -30°C.
  20. 一种干巾的加工方法,包括以下步骤:A method for processing dry towels, including the following steps:
    步骤1:将冻干功效物溶解或分散于冻干肤感剂中;Step 1: Dissolve or disperse the freeze-dried functional substance in the freeze-dried skin feel agent;
    步骤2:将冻干功效物与冻干肤感剂的混合物加温熔融至具有流动性;Step 2: The mixture of the freeze-dried functional substance and the freeze-dried skin feel agent is heated and melted to have fluidity;
    步骤3:涂布于基布表面,-50℃~-30℃冷冻干燥;Step 3: Coat on the surface of the base cloth, freeze-dry at -50℃~-30℃;
    或者通过以下方法加工:Or process by the following methods:
    步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒在冻干纤维表面或与冻干纤维相互浸润,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the freeze-dried fiber or infiltrate the freeze-dried fiber, and freeze-dry at -50°C to -30°C;
    步骤2:冻干膜与基布复合;Step 2: The freeze-dried film is combined with the base fabric;
    或者通过以下方法加工:Or process by the following methods:
    步骤1:将冻干功效物和/或冻干肤感剂溶解或分散在水或其他溶液中,喷洒于基布表面,-50℃~-30℃冷冻干燥;Step 1: Dissolve or disperse the freeze-dried functional substance and/or freeze-dried skin feel agent in water or other solutions, spray on the surface of the base fabric, and freeze-dry at -50°C to -30°C;
    步骤2:与离型层复合形成终产品;Step 2: Compound with the release layer to form the final product;
    或者通过以下方法加工:Or process by the following methods:
    步骤1:将冻干纤维加水或水溶液,-50℃~-30℃冷冻干燥后,与基布进行混纺复合;Step 1: Add water or aqueous solution to the freeze-dried fiber, freeze-dried at -50°C to -30°C, and blend and compound with the base fabric;
    步骤2:与离型层复合形成终产品。Step 2: Compound with the release layer to form the final product.
  21. 如权利要求20所述的干巾的加工方法,其特征在于:The method for processing dry towels according to claim 20, wherein:
    所述冻干膜层包括冻干功效物和/或冻干肤感剂和/或冻干纤维组成分,其中,所述冻干功效物选自西药成分、中药成分、天然提取物、生物活性成分、皮肤护理有益成分中的一种或组合,所述冻干肤感剂选自蛋白类、多糖及其盐类、高分子聚合物类、多元醇类、天然及合成油脂类、表面活性剂类中的一种或组合,所述冻干纤维为胶原蛋白纤维、壳聚糖纤维、海藻盐纤维、藻壳共混纤维、羧甲基纤维素纤维中的一种或组合。The freeze-dried film layer includes a freeze-dried functional substance and/or a freeze-dried skin feel agent and/or a freeze-dried fiber component, wherein the freeze-dried functional substance is selected from western medicine ingredients, traditional Chinese medicine ingredients, natural extracts, biological activities One or a combination of ingredients, skin care beneficial ingredients, the freeze-dried skin feel agent is selected from the group consisting of proteins, polysaccharides and their salts, high molecular polymers, polyols, natural and synthetic oils, and surfactants The freeze-dried fiber is one or a combination of collagen fiber, chitosan fiber, seaweed salt fiber, algae shell blend fiber, and carboxymethyl cellulose fiber.
  22. 如权利要求21所述的干巾的加工方法,其特征在于,所述冻干功效物中的西药成分为酮洛芬、布洛芬、萘甲唑啉、双氯芬酸二乙胺、酮康唑、氢化可的松、咪康唑氯倍他索、曲咪新、间苯二酚,所述中药成分为冰片、薄荷、樟脑、甘草、黄芩、姜黄、大黄、硫磺、苦参、蛇床子、黄连、黄柏、炉甘石、氧化锌,所述天然提取物为橙皮苷提取物、加拿大红枫提取物、黄芩根提取物、无患子提取物、脂肪酸酰胺烷基甜菜碱、积雪草提取物、针叶樱桃提取物、芍药根提取物、莲花提取物、雪莲提取物、人参根提取物、黄瓜果提取、芦荟叶提取物、马齿苋提取物、甘牛至叶提取物、接骨木提取物、玫瑰提取物、海藻提取物、松露提取物、冬虫夏草提取物、西红花提取物、银耳提取物、当归提取物、五味子提取物、母菊花提取物、山茶花提取物、白术提取物、三七提取物、姜根提取物、白芨提取物、白鲜皮提取物、薰衣草提取物、白蒺藜提取物或霍霍巴叶提取物,所述生物活性成分为表皮生长因子、寡肽-1、芽孢杆菌发酵产物、乙酰基四肽-2、乙酰基六肽-1、棕榈酰三肽、铜肽、肌肽、氨基丁酸或木瓜蛋白酶,所述皮肤护理成分为橙皮苷、牛奶蛋白、乙酰基六肽-1、芽孢杆菌发酵产物、月桂酰谷氨酸钠、乙酰化透明质酸钠、神经酰胺、椰油基甜菜碱、水杨酸、乳酸、羟基乙酸、谷胱甘肽、SOD、辅酶Q10、烟酰胺、生育酚及衍生物、视黄醇及衍生物、抗坏血酸及衍生物、海藻糖、糖类同分异构体、角鲨烷、乳木果油、阿魏酸、胶原蛋白、甘油葡糖苷、咖啡因、四氢甲基嘧啶羧酸、红没药醇、水飞蓟素、白藜芦醇、植物甾醇或虾青素;The method for processing dry towels according to claim 21, wherein the western medicine ingredients in the freeze-dried product are ketoprofen, ibuprofen, naphazoline, diclofenac diethylamine, ketoconazole, Hydrocortisone, miconazole, clobetasol, trichomidine, resorcinol, and the traditional Chinese medicine ingredients are borneol, peppermint, camphor, licorice, scutellaria, turmeric, rhubarb, sulfur, sophora flavescens, cnidii, and coptis , Cork, calamine, zinc oxide, the natural extracts are hesperidin extract, Canadian red maple extract, scutellaria root extract, Sapindus extract, fatty acid amide alkyl betaine, Centella asiatica extract Extract, acerola cherry extract, peony root extract, lotus extract, snow lotus extract, ginseng root extract, cucumber fruit extract, aloe leaf extract, portulaca extract, sweet oregano leaf extract, elder bone Wood extract, rose extract, seaweed extract, truffle extract, cordyceps extract, saffron extract, white fungus extract, angelica extract, schisandra extract, mother flower extract, camellia extract, atractylodes macrocephala extract , Panax notoginseng extract, ginger root extract, Bletilla striata extract, white fresh bark extract, lavender extract, Tribulus terrestris extract or jojoba leaf extract, the biologically active ingredients are epidermal growth factor, oligopeptide-1 , Bacillus fermentation product, acetyl tetrapeptide-2, acetyl hexapeptide-1, palmitoyl tripeptide, copper peptide, carnosine, aminobutyric acid or papain, the skin care ingredients are hesperidin, milk protein, Acetyl hexapeptide-1, Bacillus fermentation product, sodium lauroyl glutamate, sodium acetylated hyaluronate, ceramide, coco betaine, salicylic acid, lactic acid, glycolic acid, glutathione, SOD , Coenzyme Q10, nicotinamide, tocopherol and derivatives, retinol and derivatives, ascorbic acid and derivatives, trehalose, carbohydrate isomers, squalane, shea butter, ferulic acid, collagen Protein, glyceryl glucoside, caffeine, tetrahydromethylpyrimidine carboxylic acid, bisabolol, silymarin, resveratrol, phytosterol or astaxanthin;
    所述冻干肤感剂中的蛋白类为可溶性糖蛋白、胶原蛋白或水解明胶,所述多糖为果聚糖、黄原胶、透明质酸钠、聚谷氨酸、糖类同分异构体、银耳多糖或海藻糖,所述多元醇为丙二醇、甘油、丁二醇或辛甘醇,所述天然及合成油脂类为矿脂、油醇,辛酸/癸酸甘油三酯或氢化棕榈油,所述高分子聚合物类为聚丙烯酸钠或卡波姆,所述表面活性剂为聚甘油-10甘油酯、聚甘油-10-硬脂酸酯、聚山梨醇酯80、椰油基甜菜碱、月桂酰谷氨酸钠或脂肪酸酰胺烷基甜菜碱。The protein in the freeze-dried skin feel agent is soluble glycoprotein, collagen or hydrolyzed gelatin, and the polysaccharide is fructan, xanthan gum, sodium hyaluronate, polyglutamic acid, and carbohydrate isomers Body, tremella polysaccharide or trehalose, the polyol is propylene glycol, glycerin, butylene glycol or caprylyl, the natural and synthetic oils are petrolatum, oleyl alcohol, caprylic/capric triglyceride or hydrogenated palm oil , The high molecular polymer is sodium polyacrylate or carbomer, and the surfactant is polyglycerol-10 glyceride, polyglycerol-10-stearate, polysorbate 80, coco-beet Alkali, sodium lauroyl glutamate or fatty acid amide alkyl betaine.
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