CN110025597A

CN110025597A - A kind of dry towel and its processing method and application

Info

Publication number: CN110025597A
Application number: CN201910199775.9A
Authority: CN
Inventors: 李和伟
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-03-15
Filing date: 2019-03-15
Publication date: 2019-07-19
Also published as: WO2020186748A1

Abstract

The invention discloses a kind of dry towel and its processing method and application, the dry towel includes base fabric carrier layer and is attached to the freeze-drying film layer in the base fabric carrier layer, the base fabric carrier layer and freeze-drying film layer and 0.0001ml/cm with freeze-dried²‑0.1ml/cm²Water contact, the freeze-drying film layer i.e. can dissolve or dissolve out.The freeze-drying film layer includes freeze-drying effect object, or further includes one or both of freeze-drying skin sense agent and freeze-drying fiber.The dry towel is contacted with water, the dissolution of freeze-drying film layer or dissolution, and then when rubbing with epidermis, the freeze-drying film layer and base fabric carrier layer are removed, and is formed a film on epidermis.It is described to can be used as skincare product, makeup removing cleaning supplies, Transdermal absorption externally applied drug patch or Wound dressing patch application.

Description

A kind of dry towel and its processing method and application

Technical field

The present invention relates to product technical field is sticked, more particularly to a kind of dry towel and its processing method and application.

Background technique

At present skin care face-cloth on the market mostly in the form of wet tissue based on, effective component is soaked in liquid condition and mask substrate Moisten, effective component is in liquid condition in facial mask, so needs to be added additive to prevent it from aoxidizing or breed bacterium, due to these The presence of additive, consumer using when will appear various discomforts, such as tingling sensation, redness, itch or other allergic phenomenas.

Such as commercially available Stridex bigcatkin willow acid cleaning anti-acne, Medicube beauty Supreme Being Qiu Fule, clean soft pore refining skin toner Cotton piece, happy poem wind cry of certain animals Truecare centella repair moisturizing essence cotton piece, DERMATORY moral Maduo benefit muting sensitive repairs gauze patch, GRAYMELIN spend juice moisturizing cotton piece, South Korea beautiful appearance efficient moisture-retention water profit cotton piece, PETITFEE/ Pu Di prince wife face moisturizing cotton piece, NIGHTINGALE Nightingale, Florence water light cotton piece etc., in the above product, effective component is mostly liquid condition, is existed effectively Ingredient is unstable, the problems such as containing additive, in addition, using when need veneer to use or be wiped repeatedly, effective component transfer It does not form a film when to skin surface, volatilization is very fast, and dissolution and Transdermal absorption speed are slow.

There are also the effective components of some mask products to be attached on film cloth with lyophilized form on the market, even keeps away although reducing Exempted from the introducing of multiple additives, but its use form is still surface stuck type, need by facial mask using a large amount of water, Essence, It is reused after conditioning liquid or other function Hquid, if that still has in functional liquid effectively with function Hquid The problem of ingredient is unstable and is also easy to produce stimulation containing additive needs a large amount of water to impregnate, and deposit if functional liquid is water In problem inconvenient to carry.

Summary of the invention

The purpose of the present invention is there is inconvenience for dry towel usage mode existing in the prior art, and provide one The dry towel of kind, after which meets water, effective component dissolution or dissolution, one wipes and can form a film in epidermis, easy to use, uses time saving province Power.

It is a further object to provide the processing technologys of the dry towel, after this processing technology is using dipping, spraying The processing method being lyophilized after freeze-drying or melt coating, simple process promote and apply convenient for commercialization.

It is a further object to provide the packagings of the dry towel, it is possible to provide good sealed environment has moisture-proof Function.

It is a further object to provide the application of the dry towel, it is Clean- to can be applied to skincare product, makeup removing Product, Transdermal absorption externally applied drug patch or Wound dressing patch.

The technical solution adopted to achieve the purpose of the present invention is:

A kind of dry towel is attached to the freeze-drying film in the base fabric carrier layer including base fabric carrier layer and with freeze-dried Layer, the dry towel and 0.0001ml/cm²-0.1ml/cm²Water contact, the freeze-drying film layer i.e. can dissolve or dissolve out.

In the above-mentioned technical solutions, the time dissolved or dissolved out is 3-10s, and freeze-drying film layer is either layering forms base fabric Freeze-drying layer on carrying layer surface is also possible to the freeze-drying layer being partly or entirely embedded in base fabric carrier layer.

Skin care, medicinal active ingredient incorporate freeze-drying film layer by special process and carry out adult freeze-drying molding, have excellent Protecting effect, and due to short texture, porous feature after freeze-drying, so that freeze-drying film layer can be collapsed rapidly using a small amount of water Structure, dissolution dissolution, and due to the evaporation of body temperature, it forms a film in Epidermal dehydration rapidly, plays corresponding skin care or medicinal deposited Expect effect.

After freeze-drying film layer and base fabric carrier layer are compound, make to be lyophilized film layer with good toughness, to prevent in process of production Breakage causes cost to waste, and protects the morphological integrity in logistics and shelf life.

In the above-mentioned technical solutions, it is described freeze-drying film layer with a thickness of 0.1 μm -300 μm.

In the above-mentioned technical solutions, the dry towel further includes release layer.Release layer plays the role of further protecting, to protect The integrality of shield freeze-drying film layer, and improve wholesomeness.Release layer is located at the side of base fabric carrier layer, can both be located at freeze-drying film The side of layer can also be located at back to the side of freeze-drying film, while release layer may also set up two layers and be located at the two of base fabric carrier layer Side.

In the above-mentioned technical solutions, the shape of the base fabric carrier layer is round, rectangular, polygon or irregular shape, institute State the deployable state of base fabric carrier layer or compressive state, the material of the base fabric carrier layer be non-woven fabrics, absorbent cotton, cotton fiber, One of bamboo fibre, alginate fibre, tencel, cuprammonium, Modal fibre are a variety of blended.

In the above-mentioned technical solutions, the release layer is one of pet, pe, pu, bopp, pvc, pp, aluminium foil or a variety of It is combined.The shapes and sizes of the release layer can be identical as the shapes and sizes of the base fabric carrier layer, and when use first loses Release layer is abandoned, then the base fabric carrier layer and freeze-drying film layer are contacted with water.

In the above-mentioned technical solutions, the freeze-drying film layer includes in freeze-drying effect object, freeze-drying skin sense agent or freeze-drying fiber A kind of or combination.It is skin care, medicinal active ingredient that effect object, which is lyophilized, and the freeze-drying skin sense agent adds the i.e. swellable dissolution of a small amount of water, Freeze-drying fiber (such as lyophilized collagen Protein filament) progress film forming can be further added when necessary to fix.

In the above-mentioned technical solutions, when the freeze-drying film layer includes freeze-drying effect object, freeze-drying skin sense agent and freeze-drying fiber, Wherein, the mass ratio of freeze-drying effect object, freeze-drying skin sense agent and freeze-drying fiber is (1-30): (0.1-50): (0.1-100)；

When the freeze-drying film layer includes freeze-drying effect object and freeze-drying skin sense agent, freeze-drying effect object and freeze-drying skin sense agent Mass ratio be (1-30): (0.1-30)；

It is described that effect object is lyophilized and fiber is lyophilized when the freeze-drying film layer is including freeze-drying effect object and with freeze-drying fiber Mass ratio is (1-100): (0.4-100)；

When the freeze-drying film layer includes freeze-drying skin sense agent and freeze-drying fiber, the freeze-drying skin sense agent and the matter that fiber is lyophilized Amount is than being (1-100): (0.2-1000).

In the above-mentioned technical solutions, freeze-drying effect object is selected from western medicine composition, traditional Chinese medicine ingredients, natural extract, biology One of active constituent, skin nursing beneficiating ingredient or combination, the freeze-drying skin sense agent are selected from protide, polysaccharide and its salt Class, high molecular polymerization species, polyalcohols, natural and one of synthetic oil lipid, surfactant-based or combination, the jelly Dry fibers are collagen fabric, in chitin fiber, seaweed salt fiber, frustule blended fiber, carboxymethyl cellulose fiber A kind of or combination.

Western medicine composition in freeze-drying effect object is Ketoprofen, brufen, naphazoline, DICLOFENAC DIETHYLAMINE, ketone Health azoles, hydrocortisone, Miconazole clobetasol, QUMIXIN, resorcinol, the traditional Chinese medicine ingredients be borneol, peppermint, camphor, Radix Glycyrrhizae, radix scutellariae, turmeric, rheum officinale, sulphur, kuh-seng, frutus cnidii, the coptis, Cortex Phellodendri, calamine, zinc oxide, the natural extract are Orange peel glucoside extract, Canadian Acer palmatum ' Atropurpureum' extract, radix scutellariae root extract, soapberry extract, fatty acid amide alkyl betaine, Gotu Kola P.E, acerola concentrate extract, Chinese herbaceous peony root extract, Flos Nelumbinis extract, Saussurea involucrata extract, ginseng root extract, The extraction of cucumber fruit, Folium Aloe extract, purslane extract, sweet wild marjoram leaf extract, elderberry extract, rose extract, Marine algae extract, truffle extract, Cordyceps extract, saffron extract, dried tremella extract, angelica extract, the five tastes Seed extract, german chamomile flower extract, camellia flower extract, Rhizoma Atractylodis Macrocephalae extract, Notogineng Extract, ginger-root extract, the bletilla striata are extracted Object, Cortex Dictamni extract, Herba Lysimachiae foenumgraeci extract, Tribulus terrestris or Jojoba leaf extract, the bioactive ingredients are Epidermal growth factor, oligopeptides -1, fermentation of bacillus product, acetyl group tetrapeptide -2, acetyl group hexapeptide -1, palmityl tripeptides, copper Peptide, carnosine, aminobutyric acid or papain, the skin caring ingredient be aurantiamarin, milk protein, acetyl group hexapeptide -1, Fermentation of bacillus product, sodium lauroyl glutamate, acetylation Sodium Hyaluronate, ceramide, coco betaine, bigcatkin willow Acid, lactic acid, hydroxyacetic acid, glutathione, SOD, Co-Q10, niacinamide, tocopherol and derivative, retinol and derivative resist Bad hematic acid and derivative, trehalose, carbohydrate isomer, saualane, shea butter, ferulic acid, collagen, glycerol glucose Glycosides, caffeine, tetrahydro methylpyrimidine carboxylic acid, bisabolol, silymarin, resveratrol, phytosterol or astaxanthin；

Protide in the freeze-drying skin sense agent is soluble glycoprotein, collagen or gelatin hydrolysate, and the polysaccharide is Levulan, xanthan gum, Sodium Hyaluronate, polyglutamic acid, carbohydrate isomer, tremella polysaccharides or trehalose, the polyalcohol For propylene glycol, glycerol, butanediol or pungent glycol, the natural and synthetic oil lipid is vaseline, oleyl alcohol, caprylic/capric glycerol three Ester or hydrogenated palm oil, the high molecular polymerization species are Sodium Polyacrylate or carbomer, and the surfactant is polyglycereol- 10 glyceride, Natrulon H-10-stearate, polysorbate80, coco betaine, sodium lauroyl glutamate or fatty acid Amido alkyl betaine.

In the above-mentioned technical solutions, the dry towel is processed by the following method:

Step 1: freeze-drying effect object is dissolved or dispersed in freeze-drying skin sense agent；

Step 2: the mixture heating that effect object and freeze-drying skin sense agent is lyophilized is melted to mobility；

Step 3: being coated on scrim surfaces, -50 DEG C~-30 DEG C freeze-dryings；

Or it processes by the following method:

Step 1: freeze-drying effect object and/or freeze-drying skin sense agent being dissolved or dispersed in water or other solution, jelly is sprayed at Dry fibers surface mutually infiltrates, -50 DEG C~-30 DEG C freeze-dryings with freeze-drying fiber；

Step 2: freeze-drying film and composite for base fabric；

Or it processes by the following method:

Step 1: freeze-drying effect object and/or freeze-drying skin sense agent being dissolved or dispersed in water or other solution, base is sprayed on Cloth surface, -50 DEG C~-30 DEG C freeze-dryings；

Step 2: being compounded to form finished product with release layer.

Or it processes by the following method:

Step 1: freeze-drying fiber being added into water or aqueous solution, after -50 DEG C~-30 DEG C freeze-dryings, is carried out with base fabric blended multiple It closes；

Step 2: being compounded to form finished product with release layer.

In the above-mentioned technical solutions, the dry towel is contacted with water, then the dissolution of freeze-drying film layer or dissolution occur with epidermis When contact or friction, the freeze-drying film layer and base fabric carrier layer are removed, and are formed a film on epidermis.

Another aspect of the present invention further includes the dry towel as skincare product, makeup removing cleaning supplies, Transdermal absorption external application The application of medicine plaster or Wound dressing patch.After user is by wiping, freeze-drying effect object of dissolution or dissolution remains in skin Upper to use as the dry towel of essence skin care, dissolution skin surface color make-up, spot etc. clean dry towel as makeup removing when can also pass through wiping It uses, it is more not dazzling than conventional makeup remover milder.It can be by the way that freeze-drying effect object of dissolution or dissolution be remained in skin after wiping On, carry out Transdermal absorption do externally applied drug use, avoid it is bottled polluted after corkage, can by wiping after will will dissolution or dissolution Freeze-drying effect object remain in skin wound, isolation the surface of a wound and external environment used as dressing, used as liquid bandage, It is polluted after avoiding common liq dressing from breaking a seal.

Another aspect of the present invention further includes the packaging of the dry towel.It can gather selected from single independent packaging and repeatedly One of packaging；The single independent packaging can be the packaging with damp proof insulation, sealing performance, such as packed, box-packed, blister pack It is dress, one of bottled, preferably aluminum-plastic blister dress, small box-packed, the capsule coffee dress of duralumin, glass packaging, one in mental package Kind；The multiple assembly package can be the packaging with damp proof insulation, sealing performance, as packed, box-packed, blister package, it is bottled in One kind or combination, preferably aluminum-plastic blister dress, small box-packed, the capsule coffee dress of duralumin, glass packaging, mental package, plastic bottle, modeling One of magazine, aluminium plastic bag or combination." the multiple assembly package " seals after can be multiple dry towel superpositions or mixing placement Be attached in an outer packing, be also possible to it is single or multiple be packaged into a subpack, multiple subpacks be encapsulated into again one it is outer In packaging.It is described it is " a " refer to independent individual, according to the shape of dry towel base fabric carrier layer can be sheet, it is curly or pressure The forms such as contracting shape.

Another aspect of the present invention further relates to the freeze-drying film layer being formed in base fabric carrier layer with lyophilized form, the jelly Photopolymer layer includes freeze-drying effect object and/or freeze-drying skin sense agent and/or freeze-drying fiber group ingredient, wherein freeze-drying effect object choosing From one of western medicine composition, traditional Chinese medicine ingredients, natural extract, bioactive ingredients, skin nursing beneficiating ingredient or combination, institute State freeze-drying skin sense agent be selected from protide, polysaccharide and its esters, high molecular polymerization species, polyalcohols, natural and synthetic oil lipid, It is one of surfactant-based or combination, the freeze-drying fiber be collagen fabric, chitin fiber, seaweed salt fiber, One of frustule blended fiber, carboxymethyl cellulose fiber or combination.

When the freeze-drying film layer includes freeze-drying skin sense agent and freeze-drying fiber, the freeze-drying skin sense agent and the matter that fiber is lyophilized Amount is than being (1-100): (0.2-1000)

In the above-mentioned technical solutions, it is described freeze-drying effect object in western medicine composition be Ketoprofen, brufen, naphazoline, DICLOFENAC DIETHYLAMINE, ketoconazole, hydrocortisone, Miconazole clobetasol, QUMIXIN, resorcinol, the traditional Chinese medicine ingredients For borneol, peppermint, camphor, Radix Glycyrrhizae, radix scutellariae, turmeric, rheum officinale, sulphur, kuh-seng, frutus cnidii, the coptis, Cortex Phellodendri, calamine, oxidation Zinc, the natural extract are orange peel glucoside extract, Canadian Acer palmatum ' Atropurpureum' extract, radix scutellariae root extract, soapberry extract, rouge Fat acid amido alkyl betaine, Gotu Kola P.E, acerola concentrate extract, Chinese herbaceous peony root extract, Flos Nelumbinis extract, saussurea involucrata mention Take object, ginseng root extract, the extraction of cucumber fruit, Folium Aloe extract, purslane extract, sweet wild marjoram leaf extract, elder Extract, rose extract, marine algae extract, truffle extract, Cordyceps extract, saffron extract, tremella extract Object, angelica extract, Schisandra chinens P.E, german chamomile flower extract, camellia flower extract, Rhizoma Atractylodis Macrocephalae extract, Notogineng Extract, ginger Root extract, bletilla striata extract, Cortex Dictamni extract, Herba Lysimachiae foenumgraeci extract, Tribulus terrestris or Jojoba leaf extract, institute Stating bioactive ingredients is epidermal growth factor, oligopeptides -1, fermentation of bacillus product, acetyl group tetrapeptide -2, acetyl group hexapeptide - 1, palmityl tripeptides, copper peptide, carnosine, aminobutyric acid or papain, the skin caring ingredient are aurantiamarin, milk egg White, acetyl group hexapeptide -1, fermentation of bacillus product, sodium lauroyl glutamate, acetylation Sodium Hyaluronate, ceramide, coconut palm Oil-based betaine, salicylic acid, lactic acid, hydroxyacetic acid, glutathione, SOD, Co-Q10, niacinamide, tocopherol and derivative, view Flavol and derivative, ascorbic acid and derivative, trehalose, carbohydrate isomer, saualane, shea butter, ferulic acid, glue Former albumen, glycosylglycerol, caffeine, tetrahydro methylpyrimidine carboxylic acid, bisabolol, silymarin, resveratrol, phytosterol Or astaxanthin；

In the above-mentioned technical solutions, the freeze-drying film layer is prepared by following steps:

3:-50 DEG C~-30 DEG C of step freeze-dryings；

Or it processes by the following method:

Step 3: said mixture is sprayed at freeze-drying fiber surface or is mutually infiltrated with freeze-drying fiber, -50 DEG C~-30 DEG C Freeze-drying；

Or it processes by the following method:

Step 1: freeze-drying fiber is added into water or aqueous solution, -50 DEG C~-30 DEG C freeze-dryings.

Another aspect of the present invention, the processing method including a kind of dry towel, comprising the following steps:

Step 3: being coated on scrim surfaces, -50 DEG C~-30 DEG C freeze-dryings；

Or it processes by the following method:

Step 2: freeze-drying film and composite for base fabric；

Or it processes by the following method:

Step 2: being compounded to form finished product with release layer；

Or it processes by the following method:

Step 2: being compounded to form finished product with release layer.

In the above-mentioned technical solutions, the freeze-drying film layer includes freeze-drying effect object and/or freeze-drying skin sense agent and/or lyophilized fibronectin Dimension group ingredient, wherein freeze-drying effect object is selected from western medicine composition, traditional Chinese medicine ingredients, natural extract, bioactive ingredients, skin One of skin care benefit ingredient or combination, the freeze-drying skin sense agent are selected from protide, polysaccharide and its esters, high molecular polymerization Species, polyalcohols, natural and one of synthetic oil lipid, surfactant-based or combination, the freeze-drying fiber are collagen One of azelon, chitin fiber, seaweed salt fiber, frustule blended fiber, carboxymethyl cellulose fiber or combination.

Compared with prior art, the beneficial effects of the present invention are:

1. effective component is attached in base fabric carrier layer in dry towel of the invention with lyophilized form, which transports in storage Moisture will not be touched in the process, in this way, not adding preservative and antibacterial agent in this dry towel, use safety coefficient height.

2. effective component is attached in base fabric carrier layer in dry towel of the invention with lyophilized form, effectively keep thermal sensitivity or The activity of easy labile element is kept, and improves using effect.

3. since there is freeze-drying film layer " porous " constituent structure to need to be swollen originally to make some normal thickeners Dissolution, because porous, the contact area and efficiency of extremely strong expansion and water have effect its short time, a small amount of water can. The freeze-drying film layer of this dry towel can utilize a small amount of (0.0001ml/cm²-0.1ml/cm²) water dissolution, can so reduce the packet of dry towel Dressing product, and adapt to the special applications in Shao Shui.Need to be added more than ten milliliters or tens milliliters compared to traditional dry film Water for, Packing Capacity is also required to be adapted to water requirement, and the water that this dry towel needs is few, and packaging can also accordingly reduce.By few The water of amount can promote effective component dissolution or dissolution reaches effect, so damage is small safer, carry using more convenient, dissolution It is stronger with Transdermal absorption.

4. effect object, freeze-drying skin sense agent and freeze-drying fiber is lyophilized and the binding force of base fabric carrier layer is not strong enough, by selection Effect object, soluble glycoprotein, levulan, third is lyophilized in Ketoprofen, radix scutellariae root extract, epidermal growth factor, milk protein etc. Skin sense agent is lyophilized in glycol, hydrogenated palm oil, polyglutamic acid sodium etc., and the freeze-drying fiber such as collagen fabric, chitin fiber has Such characteristic, so it " can be detached from " matrix, but itself all has " film forming " again, it is possible to after " being detached from matrix " " forming a film again ".When using dry towel, after a small amount of water-soaked, one is wiped on epidermis, and film is lyophilized described in wiping process Layer is removed with base fabric carrier layer, is dehydrated on epidermis and is formed a film again, and corresponding effect can be played after film forming, and application method is easy, It avoids and wears bring inconvenience for a long time.

Specific embodiment

Below in conjunction with specific embodiment, invention is further described in detail.It should be appreciated that described herein specific Embodiment is only used to explain the present invention, is not intended to limit the present invention.

Embodiment 1

A kind of dry towel is attached to the freeze-drying film in the base fabric carrier layer including base fabric carrier layer and with freeze-dried Layer, the dry towel and 0.01ml/cm²Water contact, the freeze-drying film layer can dissolve in 10s, freeze-drying effect in detection 1min Object dissolution rate reaches 90% or more.It is described freeze-drying film layer with a thickness of 100 μm.The shape of the base fabric carrier layer is circular non-woven Cloth, the freeze-drying film layer include freeze-drying effect object, freeze-drying skin sense agent and freeze-drying fiber, freeze-drying effect object be milk protein, Acetyl group hexapeptide -1, fermentation of bacillus product, the freeze-drying skin sense agent are Sodium Hyaluronate, polyglutamic acid sodium, the freeze-drying Fiber is collagen fabric.

The dry towel is processed by the following method:

Step 1: thoroughly by 10% milk protein, 0.02% acetyl group hexapeptide -1,0.1% fermentation of bacillus product, 0.1% Bright matter acid sodium, 0.05% polyglutamic acid sodium are dissolved in water after being sufficiently mixed, and the glue of 45g/ ㎡ is sprayed at the ratio of 600-800g/ ㎡ Former azelon surface carries out -50 DEG C~-30 DEG C vacuum freeze dryings sufficiently after infiltration, forms the freeze-drying film of 100 μ m-thicks；

Step 2: freeze-drying film carries out compound, the formation dry towel of essence with pure cotton non-woven fabrics.

As the dry towel of essence, when skin care, is used for dry towel in the present embodiment.In use, the dry towel is connect with water first Touching, the dissolution of freeze-drying film layer or dissolution, then when rubbing with epidermis, the freeze-drying film layer and base fabric carrier layer are removed, It forms a film on epidermis, essence can play the role of skin care.

The packaging structure of dry towel in the present embodiment is that multi-disc aggregation type plastics are box-packed, and outside is cased with aluminium plastic bag.

Freeze-drying effect object, freeze-drying skin sense agent and the mass ratio that fiber is lyophilized are adjusted in the present embodiment, specifically, by step 1 adjustment are as follows: by 9% milk protein, 0.5% acetyl group hexapeptide -1,0.5% fermentation of bacillus product, 0.9% hyaluronic acid Sodium, 0.1% polyglutamic acid sodium are dissolved in water after being sufficiently mixed, and the collagen fabric of 10g/ ㎡ is sprayed at the ratio of 1000g/ ㎡ Surface carries out -50 DEG C~-30 DEG C vacuum freeze dryings sufficiently after infiltration.The dry towel of obtained essence has the same effect.

Comparative example 1-1: it is made using the similar formula of embodiment 1.

A kind of common essence facial mask is formulated as water (to 100%), 10% milk protein, 0.02% acetyl group hexapeptide -1, 0.1% fermentation of bacillus product, 0.1% Sodium Hyaluronate, 0.05% polyglutamic acid sodium, 0.5% Phenoxyethanol, 0.2% Buddhist nun Moor tortoise beetle ester, 0.2% polysorbate80.

Film cloth is pure cotton non-woven fabrics, and it is box-packed that packaging is generally multiple-piece plastics.

In use, generating certain irritation, careless pleasing to the eye rear tingle to epidermis since ingredient contains preservative.

The multiple skin irritation test of rabbit shows that the dry towel of embodiment 1 is " non-stimulated ", and the facial mask of comparative example 1 is " light Microstimulation ".

For milk protein, acetyl group hexapeptide -1 content trace test the result shows that, product encapsulation after, by embodiment 1 Dry towel and the facial mask of comparative example 1 be placed in milk protein and acetyl group hexapeptide -1 in identical shady and cool library after 1 year, in embodiment 1 Content loss be lower than 5%, milk protein loss 20% in the facial mask of comparative example 1, the loss of acetyl group hexapeptide -1 35%；For work Property object stability have significant difference.

The detection of epidermis water content is carried out using the quick moisture detector of skin, the dry towel in embodiment 1 wipes 5 times in epidermis (used time 15s) afterwards, epidermis water content are promoted to 56% from initial value 28%；In comparative example 1 after facial mask surface application 15s, epidermis is aqueous Amount is promoted to 32% from initial value 28%, and after surface application 5min, epidermis water content is promoted to 53% from initial value 28%.It can see Out, the dry towel of essence is due to effectively increasing skin hydration degree in skin surface quick film-forming.

Comparative example 1-2

Replenishing water and preserving moisture essence wet tissue (brand: beautiful appearance, commercially available): its be formulated in contain: water, butanediol, propylene glycol, double third Glycol (anti-corrosion), 1,2 hexylene glycols (anti-corrosion), purslane extract, allantoin, Miglyol 812N, Sensiva SC50, Dried tremella extract, xylitol, EDETATE SODIUM, glucolactone, papaya extract, glucose, salicylic acid.This is commercially available wet Containing a large amount of polyalcohols with anti-corrosion function in towel, there is certain irritation, and do not form a film after wiping, can volatilize quickly Fall, essential ingredient is allowed to be difficult to stop.

Embodiment 2

A kind of dry towel is attached to the freeze-drying film in the base fabric carrier layer including base fabric carrier layer, with freeze-dried Layer and release layer, the dry towel and 0.1ml/cm²Water contact, the shape of the base fabric carrier layer is rectangular non-woven fabrics, material For tencel, the freeze-drying film layer can dissolve in 5s, and freeze-drying effect object dissolution rate reaches 90% or more in detection 1min.The jelly Photopolymer layer with a thickness of 300 μm.The freeze-drying film layer is freeze-drying effect object, and freeze-drying effect object is soapberry extract, coconut palm Oil-based betaine, sodium lauroyl glutamate, acetylation Sodium Hyaluronate；The release layer and base fabric carrier layer geomery one It causes, material pu.

The dry towel is processed by the following method:

Step 1: by 15% soapberry extract, 5% coco betaine, 3% sodium lauroyl glutamate, 0.1% acetyl Change Sodium Hyaluronate and be dissolved in water, deaeration is sprayed on scrim surfaces, carries out -50 DEG C~-30 DEG C vacuum freeze dryings, forms 300 μm Freeze-drying film layer afterwards；

Step 2: being compounded to form finished product with release layer.

Dry towel in the present embodiment is used as the makeup removing dry towel of face cleaning.In use, first contacting the dry towel with water, freeze Photopolymer layer dissolution or dissolution, then when being wiped with epidermis, the freeze-drying film layer and base fabric carrier layer removing, on epidermis at Film, can dissolve skin surface color make-up, spot etc. after film forming and cleans dry towel as makeup removing and uses, and can further depth face cleaning.

The packaging structure of dry towel in the present embodiment is that multi-disc aggregation type plastic-aluminum is packed.

Comparative example 2-1: it is made using the similar formula of embodiment 2.

A kind of makeup remover includes water (to 100%), 15% soapberry extract, 5% coco betaine, 3% lauroyl Sodium glutamate, 0.1% acetylation Sodium Hyaluronate be molten, 0.3% methylisothiazolinone.

Using the makeup removing cotton piece of tencel material, the every absorption above-mentioned makeup remover of about 5g, single removes ornaments and formal dress usage amount as 6 makeup removings Cotton piece also needs facial cleanser progress face cleaning of in addition arranging in pairs or groups after use.Due to a large amount of contact surface activating agents, skin is dry after daily makeup removing It is dry, cuticula is thinning, easy sensitivity, generate other skin problems.

Using the dry towel of the makeup removing of embodiment 2, single makeup removing needs 2, and dissolution is after skin surface film forming, and again plus water can To use as facial cleanser, the exposure of surfactant and skin is substantially reduced, protects skin water and oil balance.

Simultaneously as not containing preservative, skin is not stimulated mildly, can be used daily.

Comparative example 2-2

Makeup removing face cleaning piece wet tissue (brand: Qin Ye, commercially available): contain in its formula: water, sodium lauroyl glutamate, lauroyl Potassium glutamate, sodium cocoyl glutamate, PVP/PVA vinyl propionate copolymer, royal jelly, glycerol, 2-pyrrolidone-5-carboxylic acid, fourth two Alcohol, Phenoxyethanol, extract of red vine leaves, hamamelis extract, Radix Malvae sylvestris extract, cucumber berry extract, Curacao reed Luxuriant growth leaf extract, Hypericum Perforatum P.E.Although the commercially available wet tissue is wet tissue form, every time using also needing to add water, unilateral side makes Just there is obvious makeup removing effect later with 3, and due to containing phenoxyethanol preservative in formula, is irritating to the skin Effect.

Embodiment 3

A kind of dry towel is attached to the freeze-drying film in the base fabric carrier layer including base fabric carrier layer and with freeze-dried Layer, the dry towel and 0.0005ml/cm²Water contact, the freeze-drying film layer can dissolve in 7s, freeze-drying effect in detection 1min Object dissolution rate reaches 90% or more.The shape of the base fabric carrier layer is rectangular non-woven fabrics, and material is absorbent cotton and pure cotton nonwoven Cloth composite, it is described freeze-drying film layer with a thickness of 5 μm.The freeze-drying film layer includes freeze-drying effect object and freeze-drying skin sense agent, institute Stating freeze-drying effect object is micromolecule hyaluronic acid sodium；The freeze-drying skin sense agent is hydrogenated palm oil, Unigly GO 102S.

The dry towel is processed by the following method:

Step 1. disperses micromolecule hyaluronic acid sodium in hydrogenated palm oil, and dispersion quality ratio is 1:9；

Mixture is heated up to 47 DEG C and melted to mobility by step 2., Unigly GO 102S is added, with mixture Ratio 1:1；

Step 3. is coated on scrim surfaces, carries out -50 DEG C of -20 DEG C of vacuum freeze dryings, solidifies mixture, and remove suction Tidewater point forms the freeze-drying film of 5 μ m-thicks.

Dry towel in the present embodiment is used as dressing patch.In use, first by the dry towel with it is few in wound The vapor contact that diffusate or skin distribute, the dissolution of freeze-drying film layer or dissolution, the freeze-drying film layer and base fabric carrier layer are removed, It forms a film on skin wound, the isolation surface of a wound, forms liquid wound patch.

The packaging structure of dry towel in the present embodiment is that one chip plastic-aluminum is packed.

In the present embodiment, make following adjustment to each formulation content: step 1. disperses micromolecule hyaluronic acid sodium in In hydrogenated palm oil, dispersion quality is respectively 10g and 0.2g；Mixture is heated up to 47 DEG C and melted to flowing by step 2. Property, Unigly GO 102S 0.8g is added；Step 3. is coated on scrim surfaces, carries out -50 DEG C of -20 DEG C of vacuum freeze dryings, makes to mix Object solidification is closed, and removes moisture absorption moisture, forms the freeze-drying film of 5 μ m-thicks.Obtained liquid wound patch has the same effect.

It is as follows to adjust each composition content again: micromolecule hyaluronic acid sodium is scattered in hydrogenated palm oil, dispersion quality difference For 1g and 25g, Unigly GO 102S 5g is added；Or micromolecule hyaluronic acid sodium is scattered in hydrogenated palm oil, dispersion quality Unigly GO 102S 0.3g is added in respectively 30g and 0.7g, and obtained liquid wound patch effect is identical.

Comparative example 3: it is made using the similar formula of embodiment 3.

A kind of liquid wound patch, includes Unigly GO 102S 5%, hydrogenated palm oil 4.5%, micromolecule hyaluronic acid sodium 0.5%, parahydroxyacet-ophenone 0.5%, water (to 100%).Need to squeeze out 5-10g when use in affected part, and packaging is difficult to again Sealing, the shelf-life 2 months after packaging unlatching.

The multiple skin irritation test of rabbit shows that the dry towel of embodiment 3 is " non-stimulated ", the liquid wound of comparative example 3 Patch is " minimal irritation ".

A large amount of water (89.5%) are needed to can achieve film-formation result in the process for preparation of the bandage of comparative example 3；Implement Dry towel in example 3 only needs the i.e. leachable film forming of diffusate few in wound, plays buffer action.

Embodiment 4

A kind of dry towel is attached to the freeze-drying film in the base fabric carrier layer including base fabric carrier layer and with freeze-dried Layer, the dry towel and 0.001ml/cm²Water contact, the shape of the base fabric carrier layer is rectangular non-woven fabrics, and material is cuprammonium Fiber and modal fiber blended, the freeze-drying film layer can dissolve in 3s, and freeze-drying effect object dissolution rate reaches in detection 1min 90% or more.It is described freeze-drying film layer with a thickness of 0.1 μm.The freeze-drying film layer includes freeze-drying effect object, freeze-drying skin sense agent and jelly Dry fibers, freeze-drying effect object are Ketoprofen, and the freeze-drying skin sense agent is carbomer and glycerol, and the freeze-drying fiber is poly- for shell Sugared fiber.

The dry towel is processed by the following method:

Step 1: by Ketoprofen 1%, carbomer 0.5% and glycerol 10% plus water (to 100%) dissolution, adjusting ph to 5.5 After certain gel viscosity (> 300cp), the chitin fiber surface of 50g/ ㎡ is coated on the ratio of 200-350g/ ㎡ ,- 50 DEG C~-25 DEG C vacuum freeze dryings form freeze-drying film layer；

Step 2: freeze-drying film layer and the blended composite for base fabric of cuprammonium/Modal form the dry towel of throe externally applied drug.

Dry towel in the present embodiment is used as transdermal externally applied drug patch.In use, first by the dry towel and a small amount of water Contact (such as the vapor contact distributed), the dissolution of freeze-drying film layer or dissolution, then when rubbing with epidermis, the freeze-drying Film layer and base fabric carrier layer are removed, and are formed a film on epidermis, effective component is utilized by way of Transdermal absorption.

The packaging structure of dry towel in the present embodiment is mono-sheet aluminum-plastic blister dress.

Ingredient in step 1 is adjusted on the basis of the present embodiment, step 1 adjusted are as follows: by Ketoprofen 1%, Carbomer 5% and glycerol 45% plus water (to 100%) dissolution, after adjusting ph to 5.5 has certain gel viscosity (> 300cp), The chitin fiber surface of 100g/ ㎡ is coated on the ratio of 100g/ ㎡, -50 DEG C~-25 DEG C vacuum freeze dryings form freeze-drying Film layer

Or step 1 adjusted are as follows: Ketoprofen 1%, carbomer 5% and glycerol 45% plus water (to 100%) are dissolved, Ph to 5.5 is adjusted with after certain gel viscosity (> 300cp), the chitosan fibre of 0.1g/ ㎡ is coated on the ratio of 100g/ ㎡ Dimension table face, -50 DEG C~-25 DEG C vacuum freeze dryings form freeze-drying film layer.On the basis of adjusting herein, the above effect can get Transdermal externally applied drug patch.

Or step 1 adjusted are as follows: Ketoprofen 30%, carbomer 5% and glycerol 45% plus water (to 100%) is molten Solution is adjusted ph to 5.5 with after certain gel viscosity (> 300cp), is gathered with the shell that the ratio of 100g/ ㎡ is coated on 0.1g/ ㎡ Sugared fiber surface, -50 DEG C~-25 DEG C vacuum freeze dryings form freeze-drying film layer.Herein adjust on the basis of, can get more than The transdermal externally applied drug patch of effect.

Or step 1 adjusted are as follows: Ketoprofen 30%, carbomer 5% and glycerol 45% plus water (to 100%) is molten Solution is adjusted ph to 5.5 with after certain gel viscosity (> 300cp), is gathered with the shell that the ratio of 100g/ ㎡ is coated on 100g/ ㎡ Sugared fiber surface, -50 DEG C~-25 DEG C vacuum freeze dryings form freeze-drying film layer.Herein adjust on the basis of, can get more than The transdermal externally applied drug patch of effect.

Comparative example 4: it is made using the similar formula of embodiment 4.

Ketoprofen 1%, carbomer 0.5% and glycerol 10% plus water (to 100%) dissolution, adjusting ph to 5.5 has centainly After gel viscosity (> 300cp), it is directly coated at chitin fiber surface, to pack after the blended composite for base fabric of cuprammonium/Modal It is used as externally applied drug.

Penetrating absorption detect drug dissolution the result shows that, 4 Ketoprofen of embodiment dissolves out ratio in 4 hours and is 3.72%, it is 1.89% that 4 Ketoprofen of comparative example dissolves out ratio in 4 hours, has significant difference.

Embodiment 5

A kind of dry towel, including release layer, base fabric carrier layer and be attached in the base fabric carrier layer with freeze-dried Freeze-drying film layer, the dry towel and 0.05ml/cm²Water contact, the freeze-drying film layer can dissolve in 6s, jelly in detection 1min Dry effect object dissolution rate reaches 90% or more.The shape of the base fabric carrier layer is oval non-woven fabrics, and material is 30% seaweed Fiber, the release layer shapes and sizes are identical as the base fabric carrier layer, material pet, the freeze-drying film layer with a thickness of 30μm.The freeze-drying film layer include freeze-drying effect object, freeze-drying skin sense agent and freeze-drying fiber, freeze-drying effect object be niacinamide, Radix scutellariae root extract, the freeze-drying skin sense agent be soluble glycoprotein, polysorbate80, caprylic/capric triglyceride, it is described The carboxymethyl cellulose fiber that fiber is 35g/ ㎡ is lyophilized.

The dry towel is processed by the following method:

Step 1: by niacinamide 3%, radix scutellariae root extract 1%, soluble glycoprotein 1%, polysorbate80 1.5%, Caprylic/capric triglyceride 2% is dissolved in water, emulsifying homogeneous is uniform, mutually infiltrates with 35g/ ㎡ carboxymethyl cellulose fiber ,- 50 DEG C~-25 DEG C vacuum freeze dryings form freeze-drying film layer；

Step 2: freeze-drying film layer and alginate fibre base fabric carrier are compound, form the dry towel of skin lightening essence.

Dry towel in the present embodiment is used as the dry towel of facial treatment essence.In use, first in the dry towel surface sprinkling and Its a small amount of water, the dissolution of freeze-drying film layer or dissolution, then when rubbing with epidermis, the freeze-drying film layer and base fabric carrier layer Removing, forms a film on epidermis, plays the purpose of skin care.

The packaging structure of dry towel in the present embodiment is seal bag.

On the basis of the present embodiment, each component content in step 1 is adjusted, specially by niacinamide 0.9%, Huang A kind of reed mentioned in ancient books root extract 0.1%, soluble glycoprotein 0.01%, polysorbate80 0.07%, caprylic/capric triglyceride 0.02% is dissolved in water, emulsifying homogeneous is uniform, and the mixture after 100g emulsification uniformly is obtained and 100g/ ㎡ carboxymethyl cellulose Fiber 1m²Mutually infiltration, -50 DEG C~-25 DEG C vacuum freeze dryings form freeze-drying film layer；The facial treatment essence obtained by this is dry Towel is identical as said effect.

When similarly making following modification to each component, it is similarly obtained the dry towel of same effect: by niacinamide 0.2%, radix scutellariae Root extract 0.1%, soluble glycoprotein 0.1%, polysorbate80 0.3%, caprylic/capric triglyceride 0.1% plus water Dissolution, emulsifying homogeneous are uniform, and the mixture after 10000g emulsification uniformly is obtained and 100g/ ㎡ carboxymethyl cellulose fiber 1m² Mutually infiltration, -50 DEG C~-25 DEG C vacuum freeze dryings form freeze-drying film layer.

Comparative example 5: it is made using the similar formula of embodiment 5.

A kind of common skin lightening essence facial mask is formulated as water (to 100%), niacinamide 3%, radix scutellariae root extract 1%, solvable Property glycoprotein 1%, polysorbate80 1.5%, caprylic/capric triglyceride 2%, 0.5% Phenoxyethanol, 0.2% nipalgin Methyl esters, 0.1% polysorbate80.

Film cloth is 30% alginate fibre, and it is box-packed to be packaged as multiple-piece plastics.

For niacinamide, radix scutellariae root extract content trace test the result shows that, product encapsulation after, by embodiment 5 Dry towel and the facial mask of comparative example 5 are placed in containing for the niacinamide and radix scutellariae root extract in identical shady and cool library after 1 year, in embodiment 1 Amount loss is lower than 4%, niacinamide loss 24%, radix scutellariae root extract 28% in the facial mask of comparative example 5；For the stabilization of active matter Property have significant difference.

The detection of epidermis water content is carried out using the quick moisture detector of skin, the dry towel in embodiment 1 wipes 5 times in epidermis (used time 15s) afterwards, epidermis water content are promoted to 49% from initial value 26%；In comparative example 1 after facial mask surface application 15s, epidermis is aqueous Amount is promoted to 30% from initial value 26%, and after surface application 5min, epidermis water content is promoted to 45% from initial value 28%.It can see Out, the dry towel of essence is due to effectively increasing skin hydration degree in skin surface quick film-forming.

Embodiment 6

A kind of dry towel, including release layer, base fabric carrier layer and be attached in the base fabric carrier layer with freeze-dried Freeze-drying film layer, the dry towel and 0.0001ml/cm²Water contact, the freeze-drying film layer can dissolve in 8s, in detection 1min Freeze-drying effect object dissolution rate reaches 90% or more.The shape of the base fabric carrier layer is eye cover-type non-woven fabrics, and material is bamboo fibre With the blend fibre of tencel, the release layer shapes and sizes are identical as the base fabric carrier layer, material pp, the freeze-drying film Layer with a thickness of 1 μm.The freeze-drying film layer is formed by effect object and freeze-drying skin sense agent is lyophilized, and freeze-drying effect object is orange peel Glycosides, Canadian Acer palmatum ' Atropurpureum' extract, acetyl group tetrapeptide -2, the freeze-drying skin sense agent is Natrulon H-10 glyceride, levulan, hydroxyl second Base urea.

The dry towel is processed by the following method:

Step 1: by aurantiamarin 1%, Canadian Acer palmatum ' Atropurpureum' extract 0.5%, acetyl group tetrapeptide -2 0.001%, polyglycereol - 10 glyceride 0.5%, levulan 0.5%, ethoxy urea 5% plus water (to 100%) dissolution, are sprayed on scrim surfaces, and -50 DEG C ~-25 DEG C of vacuum freeze dryings；

Step 2: being compounded to form finished product with pp release layer.

Dry towel in the present embodiment is used as periocualr skin nursing towel, and product is sewed in combination in steam eye patch Survey surface, and monolithic independent packaging.In use, steam eye patch can generate 0.0001ml/cm²Water vapour, survey surface with interior After nursing towel contact, the dissolution of freeze-drying film layer, dissolution remove with base fabric carrier layer, form a film on eye circumference epidermis, obtain periocualr skin The result of nursing.

The packaging structure of dry towel in the present embodiment is hermetic bag packaging.

Comparative example 6: it is made using the similar formula of embodiment 6.

A kind of eye circumference nursing wet tissue, including release layer and wet tissue, in the wet tissue formula of conditioning liquid be water (extremely 100%), aurantiamarin 1%, Canadian Acer palmatum ' Atropurpureum' extract 0.5%, acetyl group tetrapeptide -2 0.001%, Natrulon H-10 glyceride 0.5%, levulan 0.5%, ethoxy urea 5%, 0.2% methylparaben, 0.1% polysorbate80.

The detection of epidermis water content is carried out using the quick moisture detector of skin, by the periocualr skin nursing towel in embodiment 6 After eye presses or massages 5 times, periocualr skin water content is promoted to 50% from 27%, and the eye circumference in comparative example nurses wet tissue After eye circumference soak 15s, periocualr skin water content is promoted to 34% from 27%, and after soak 5min, periocualr skin water content is promoted To 46%.

Embodiment 7

A kind of dry towel, including release layer, base fabric carrier layer and be attached in the base fabric carrier layer with freeze-dried Freeze-drying film layer, the dry towel and 0.1ml/cm²Water contact, the freeze-drying film layer can dissolve in 9s, jelly in detection 1min Dry effect object dissolution rate reaches 90% or more.The shape of the base fabric carrier layer be rectangular non-woven fabrics, material is pure cotton, it is described from Type layer shapes and sizes are identical as the base fabric carrier layer, material pe, the freeze-drying film layer with a thickness of 85 μm.The freeze-drying Film layer include freeze-drying effect object, freeze-drying skin sense agent and freeze-drying fiber, freeze-drying effect object be fatty acid amide alkyl betaine, Freeze-drying skin sense agent is oleyl alcohol, vaseline, Natrulon H-10-stearate, and the freeze-drying fiber is water soluble algae fiber.

The dry towel is processed by the following method:

Step 1: fatty acid amide alkyl betaine is distributed in oleyl alcohol, and dispersion ratio is 1:1；

Step 2: by vaseline: Natrulon H-10-stearate=2:1 mixture, which is warmed to 60 DEG C and melts to, has flowing Property, and after step 1 mixture is with the mixing of 1:1 ratio, the water solubility sea of 50g/ ㎡ is coated on according to the ratio of 150-250g/ ㎡ Algae fiber surface；

Step 3: being coated on scrim surfaces, -50 DEG C~-20 DEG C freeze-dryings.

Dry towel in the present embodiment is used as the dry towel of eye makeup removing.In use, first contacting the dry towel with water, freeze Photopolymer layer emulsification, dissolution and dissolution, then when rubbing with epidermis, the freeze-drying film layer and base fabric carrier layer are removed, It forms a film on epidermis, after dissolving eye color make-up, carries out erasing makeup removing by continuing wiping.

When carrying out eye makeup removing using the dry towel of eye makeup removing of the present embodiment, it need to only wipe 2 times and cooperate facial cleanser or clear again Water cleaning needs when can clean up, and nonirritant by eye cosmetic, and use common makeup-removing wet tissue using 3-4 Piece wet tissue, ability erasable is clean, and due to the preservative in wet tissue, eye can be stimulated to shed tears.

Embodiment 8

A kind of dry towel is attached to the freeze-drying film in the base fabric carrier layer including base fabric carrier layer and with freeze-dried Layer, the dry towel and 0.05ml/cm²Water contact, the freeze-drying film layer can dissolve in 4s, freeze-drying effect object in detection 1min Dissolution rate reaches 90% or more.The shape of the base fabric carrier layer is circular non-woven cloth, and material is tencel and the blended nonwoven of cuprammonium Cloth, it is described freeze-drying film layer with a thickness of 10 μm.The freeze-drying film layer only includes freeze-drying effect object, and freeze-drying effect object is epidermis Growth factor.

The dry towel is processed by the following method:

Step 1: after adding water (to 400ml) to dissolve epidermal growth factor 6mg, being sprayed on the blended base fabric of tencel and cuprammonium Surface, -50 DEG C~-30 DEG C vacuum freeze dryings；

Step 2: the packaging dry towel of ingredient skin healing dressing.

Dry towel in the present embodiment is used as the dry towel of dressing.In use, can directly with the wound fluid of skin surface Contact, or a small amount of sterile water of sprinkling make that film layer dissolution or dissolution, then when rubbing with epidermis, the freeze-drying film is lyophilized Layer is removed with base fabric carrier layer, is formed a film on epidermis, is played the role of skin nursing, is promoted healing.

When towel dry using the dressing of the present embodiment, wiped twice in wound, wound is isolated with external environment, and wound is cured Closing the time is 10h or so, and uses the liquid bandage containing epidermal growth factor, and wound healing time is left and right for 24 hours.

Embodiment 9

A kind of dry towel is attached to the freeze-drying film in the base fabric carrier layer including base fabric carrier layer and with freeze-dried Layer, the dry towel and 0.005ml/cm²Water contact, the freeze-drying film layer can dissolve in 4s, freeze-drying effect in detection 1min Object dissolution rate reaches 90% or more.The shape of the base fabric carrier layer is rectangular non-woven fabrics, and material is the blended of pure cotton and tencel, It is described freeze-drying film layer with a thickness of 2 μm.The freeze-drying film layer includes freeze-drying effect object and freeze-drying fiber, and freeze-drying effect object is Salicylic acid, papain, the freeze-drying fiber are collagen fabric.

The dry towel is processed by the following method:

Step 1: by salicylic acid 0.1%, papain 1% plus water (to 100%) dissolution, with the ratio of 200-300g/ ㎡ Example is sprayed at the collagen fabric surface of 28g/ ㎡, -50 DEG C~-30 DEG C vacuum freeze dryings；

Step 2: the blended composite for base fabric of freeze-drying film and pure cotton and tencel forms the dry towel of cutin softening.

Dry towel in the present embodiment is used as the dry towel of cutin softening.In use, first contacting the dry towel with water, freeze Photopolymer layer dissolution or dissolution, then when rubbing with epidermis, the freeze-drying film layer and base fabric carrier layer are removed, on epidermis Film forming, cutin-softening achieve the effect that skin highlights.

On the basis of the present embodiment, do following adjustment to component content: salicylic acid 0.5%, papain 0.5% add Water (to 100%) dissolution, the 100ml solution that will be obtained spray 1m²On the collagen fabric surface of 100g/ ㎡；

Or salicylic acid 0.5%, papain 0.5% plus water (to 100%) dissolution, the 10000ml solution that will be obtained spray Spill 1m²On the collagen fabric surface of 0.4g/ ㎡；

Or salicylic acid 0.5%, papain 0.5% plus water (to 100%) dissolution, the 100ml solution that will be obtained spray 1m²On the collagen fabric surface of 0.4g/ ㎡；All obtain the dry towel of the identical cutin softening of effect.

Comparative example 9

Cutin-softening wet tissue cotton piece (brand: spring rain, commercially available): its be formulated in water, methyl propanediol (irritation), 1,2 oneself Glycol (anti-corrosion), PEG/PPG-17-6 copolymer, alcohol (irritation), birch water, lactic acid (irritation), hydroxyacetic acid (stimulation Property), dipropylene glycol (anti-corrosion), eggplant berry extract, Sodium Hyaluronate, salicylic acid (irritation), licorice root extract, ethyl hexyl Glycol, grape berry extract, apple extract, lemon berry extract, bigarabe extract, citrus extracts, Gotu Kola P.E, Tea extract, Chuan Su leaf extract, pot marigold leaf extract, PEG-60 rilanit special, benzotriazole base butylbenzene phenol sulfonic acid Sodium (sun-screening agent), polyglyceryl ether -26, butylol polyether -3 (irritation), tributyl citrate (irritation), trehalose, glycine betaine, Allantoin, cape jasmine berry extract, tromethamine, dextrin, EDETATE SODIUM, butanediol, polysorbate -20, citric acid, acryloyl Dimethyl/VP copolymer, glycerol caprylate, Sensiva SC50.The wet tissue dough sheet has while cutin-softening compared with strong stimulation Property, it is larger to the security risk hidden danger of skin.

Embodiment 10

A kind of dry towel, including the double-deck release layer, base fabric carrier layer and the base fabric carrier is attached to freeze-dried Freeze-drying film layer on layer, the dry towel and 0.08ml/cm²Water contact, the freeze-drying film layer can dissolve in 8s, detection 1min Interior freeze-drying effect object dissolution rate reaches 90% or more.The shape of the base fabric carrier layer is rectangular non-woven fabrics, and material is common nothing The character of woven fabric, the release layer is consistent with base fabric carrier layer, and the double-deck material is respectively bopp and aluminium foil, the thickness of the freeze-drying film layer Degree is 150 μm.The freeze-drying film layer includes freeze-drying effect object, freeze-drying skin sense agent and freeze-drying fiber, and freeze-drying effect object is mind Through amide, calamine, zinc oxide, the freeze-drying skin sense agent is propylene glycol, glycerol, and the freeze-drying fiber is alginate fibre.

The dry towel is processed by the following method:

Step 1: ceramide 0.1%, calamine 2%, zinc oxide 1%, propylene glycol 2%, glycerol 15% are dissolved in water (extremely 100%) alginate fibre surface, -50 DEG C of -25 DEG C of vacuum freeze dryings, are sprayed on；

Step 2: above-mentioned freeze-drying film layer and non-woven fabrics composite for base fabric；

Step 3: being compounded to form finished product with the double-deck release layer.

Dry towel in the present embodiment is nursed dry towel as fash externally applied drug and is used.In use, dry towel occurs with wound mouth When contact, wound tissue's liquid of exudation can promote the dissolution of freeze-drying film layer or dissolution, described then when rubbing with epidermis Film layer is lyophilized and base fabric carrier layer is removed, forms a film on epidermis, goes detumescence of itching, play the role of adjuvant treatment.

It after the completion of dry towel wiping is nursed in the externally applied drug of the present embodiment, can have effect, guarantee that skin is dry and comfortable, and baste After body or drug paste, it is unfavorable for the recovery of fash.

Embodiment 11

A kind of dry towel, including release layer, base fabric carrier layer and be attached in the base fabric carrier layer with freeze-dried Freeze-drying film layer, the dry towel and 0.03ml/cm²Water contact, the freeze-drying film layer can dissolve in 6s.The base fabric carrier The shape of layer is irregular shape, and material is non-woven fabrics, and the release layer is consistent with the character of base fabric carrier layer, material pu, institute State freeze-drying film layer with a thickness of 15 μm.The freeze-drying film layer includes freeze-drying skin sense agent, and the freeze-drying skin sense agent is xanthan gum, tremella Polysaccharide.

The dry towel is processed by the following method:

Step 1: by xanthan gum 0.2%, tremella polysaccharides 0.3% plus water (to 100%) dissolution, it is coated on scrim surfaces, -50 DEG C of -30 DEG C freeze-dryings；

Step 2: being compounded to form finished product with release layer.

Dry towel in the present embodiment is used as the dry towel of moisturizing essence.In use, first contacting the dry towel with water, freeze Photopolymer layer dissolution or dissolution, then when rubbing with epidermis, the freeze-drying film layer and base fabric carrier layer are removed, on epidermis Film forming, plays the role of skin-moisturizing, skin.

The dry towel of the moisturizing essence of the present embodiment wipes 3 times, and moisture content of skin can reach 49% after 10s, commercially available common wet tissue, Soak 10-15min is generally required, moisture content of skin just can reach 45%.

Embodiment 12

A kind of dry towel, including release layer, base fabric carrier layer and be attached in the base fabric carrier layer with freeze-dried Freeze-drying film layer, the dry towel and 0.0015ml/cm²Water contact, the freeze-drying film layer can dissolve in 7s.The base fabric carries The shape of body layer is rectangle, and material is bamboo fibre, and the release layer shape is consistent with base fabric carrier layer, and material PVC is described Be lyophilized film layer with a thickness of 25 μm.The freeze-drying film layer is freeze-drying fiber, and the freeze-drying fiber is alginate fibre.

The dry towel is processed by the following method:

Step 1: 0.2% sodium citrate solution is added in alginate fibre, after -50 DEG C~-30 DEG C freeze-dryings, with base fabric It carries out compound；

Step 2: being compounded to form finished product with release layer.

Dry towel in the present embodiment is suitble to baby's dry and wet towel to use.In use, first by the dry towel and 0.0015ml/ cm²Water contact, by the moisture in skin moisture itself or air, film layer, which is lyophilized, can also complete to dissolve or be dissolved out in 7s, Then when rubbing with epidermis, the freeze-drying film layer and base fabric carrier layer are removed, and are formed a film on epidermis, play moisturizing, profit The effect of skin.

Comparative example 12

A kind of baby wipes include 2% sodium alginate, 0.1% pentanediol, water (to 100%).It is directly wiped when use, But due to after high frequency use, having an impact to baby's epidermis flora containing pentanediol, inhibit epidermis flora growth (inhibiting rate 30%), infant skin health is had an impact.

Embodiment 13

A kind of dry towel is attached to the freeze-drying film in the base fabric carrier layer including base fabric carrier layer and with freeze-dried Layer, the dry towel and 0.02ml/cm²Water contact, the freeze-drying film layer can dissolve in 5s.The shape of the base fabric carrier layer For irregular shape, material is non-woven fabrics, it is described freeze-drying film layer with a thickness of 2.5 μm.The freeze-drying film layer includes freeze-drying skin sense agent With freeze-drying fiber, the freeze-drying skin sense agent is carbohydrate isomer, pungent glycol and Sodium Polyacrylate, and the freeze-drying fiber is sea Algae fiber.

The dry towel is processed by the following method:

Step 1: adding water (to 100%) molten carbohydrate isomer 1.5%, pungent glycol 5%, Sodium Polyacrylate 0.2% Solution, the alginate fibre surface of 65g/ ㎡ is coated on the ratio of 15-35g/ ㎡, and -50 DEG C of -30 DEG C of freeze-dryings form freeze-drying film；

Step 2: above-mentioned freeze-drying film and carrier layer are compounded to form finished product.

Dry towel in the present embodiment is used as the dry towel of moisturizing essence.In use, first by the dry towel and 0.02ml/ cm²Water contact, freeze-drying film layer dissolve or dissolve out in 5s, then in epidermis wiping, the freeze-drying film layer and base fabric carrier layer Removing, forms a film on epidermis, plays the role of skin-moisturizing, skin.

The dry towel of the moisturizing essence of the present embodiment wipes 2 times, and moisture content of skin can reach 50% after 15s, commercially available common wet tissue, Soak 10-15min is generally required, moisture content of skin just can reach 40%.

On the basis of the present embodiment, following adjustment is made to a constituent content:

Step 1: carbohydrate isomer 0.8%, pungent glycol 0.1%, Sodium Polyacrylate 0.1% are added into water (to 100%) Dissolution, takes 100ml, ratio be coated on the alginate fibre surface of 0.2g/ ㎡, -50 DEG C of -30 DEG C of freeze-dryings form freeze-drying film；

Or step 1: (extremely by carbohydrate isomer 0.8%, pungent glycol 0.1%, Sodium Polyacrylate 0.1% plus water 100%) dissolve, take 100ml, ratio be coated on the alginate fibre surface of 1000g/ ㎡, -50 DEG C of -30 DEG C of freeze-dryings are formed Film is lyophilized；

Or step 1: (extremely by carbohydrate isomer 0.8%, pungent glycol 0.1%, Sodium Polyacrylate 0.1% plus water 100%) dissolve, take 10000ml, ratio be coated on the alginate fibre surface of 0.2g/ ㎡, -50 DEG C of -30 DEG C of freeze-dryings, shape Gelation dry film；

The adjustment of the above components obtains the dry towel of moisturizing essence with 13 same effect of embodiment.

The above is only a preferred embodiment of the present invention, it is noted that for the common skill of the art For art personnel, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications Also it should be regarded as protection scope of the present invention.

Claims

1. a kind of dry towel is attached to the freeze-drying film in the base fabric carrier layer including base fabric carrier layer and with freeze-dried Layer, which is characterized in that the base fabric carrier layer and freeze-drying film layer and 0.0001ml/cm²-0.1ml/cm²Water contact, the jelly Photopolymer layer can dissolve or dissolution.

2. dry towel as described in claim 1, which is characterized in that the time of the freeze-drying film layer dissolution or dissolution is 3-10s.

3. dry towel as described in claim 1, which is characterized in that the freeze-drying film layer with a thickness of 0.1 μm -300 μm.

4. dry towel as described in claim 1, which is characterized in that the dry towel further includes release layer.

5. dry towel as claimed in claim 4, which is characterized in that the release layer is one or two layers, and the release layer is located at The one or both sides of the freeze-drying film layer of the base fabric carrier layer.

6. dry towel as claimed in claim 4, which is characterized in that the release layer is pet, pe, pu, bopp, pvc, pp, aluminium foil One of or combination.

7. dry towel as described in claim 1, which is characterized in that the base fabric carrier layer be non-woven fabrics, absorbent cotton, cotton fiber, One of bamboo fibre, alginate fibre, tencel, cuprammonium, Modal fibre are a variety of blended.

8. dry towel as described in claim 1, which is characterized in that the freeze-drying film layer includes freeze-drying effect object, freeze-drying skin sense agent Or freeze-drying one of fiber or combination.

9. dry towel as claimed in claim 8, which is characterized in that when the freeze-drying film layer includes freeze-drying effect object, freeze-drying skin sense When agent and freeze-drying fiber, wherein the mass ratio of freeze-drying effect object, freeze-drying skin sense agent and freeze-drying fiber is (1-30): (0.1- 50): (0.1-100)；

When the freeze-drying film layer includes freeze-drying effect object and freeze-drying skin sense agent, freeze-drying effect object and the matter that skin sense agent is lyophilized Amount is than being (1-30): (0.1-30)；

When the freeze-drying film layer is including freeze-drying effect object and with freeze-drying fiber, freeze-drying effect object and the quality that fiber is lyophilized Than for (1-100): (0.4-100)；

When the freeze-drying film layer includes freeze-drying skin sense agent and freeze-drying fiber, the freeze-drying skin sense agent and the mass ratio that fiber is lyophilized For (1-100): (0.2-1000).

10. dry towel as claimed in claim 8, which is characterized in that freeze-drying effect object selected from western medicine composition, traditional Chinese medicine ingredients, One of natural extract, bioactive ingredients, skin nursing beneficiating ingredient or combination, the freeze-drying skin sense agent are selected from albumen Class, polysaccharide and its esters, high molecular polymerization species, polyalcohols, natural and one of synthetic oil lipid, surfactant-based Or combination, the freeze-drying fiber are collagen fabric, chitin fiber, seaweed salt fiber, frustule blended fiber, carboxymethyl fibre One of cellulose fiber or combination.

11. dry towel as claimed in claim 10, which is characterized in that the western medicine composition in freeze-drying effect object be Ketoprofen, Brufen, naphazoline, DICLOFENAC DIETHYLAMINE, ketoconazole, hydrocortisone, Miconazole clobetasol, QUMIXIN, isophthalic two Phenol, the traditional Chinese medicine ingredients are borneol, peppermint, camphor, Radix Glycyrrhizae, radix scutellariae, turmeric, rheum officinale, sulphur, kuh-seng, frutus cnidii, the coptis, Huang Cypress, calamine, zinc oxide, the natural extract be orange peel glucoside extract, Canadian Acer palmatum ' Atropurpureum' extract, radix scutellariae root extract, Soapberry extract, fatty acid amide alkyl betaine, Gotu Kola P.E, acerola concentrate extract, Chinese herbaceous peony root extract, lotus Flower extract, Saussurea involucrata extract, ginseng root extract, the extraction of cucumber fruit, Folium Aloe extract, purslane extract, sweet wild marjoram Leaf extract, elderberry extract, rose extract, marine algae extract, truffle extract, Cordyceps extract, west safflower Extract, dried tremella extract, angelica extract, Schisandra chinens P.E, german chamomile flower extract, camellia flower extract, Rhizoma Atractylodis Macrocephalae extract Object, Notogineng Extract, ginger-root extract, bletilla striata extract, Cortex Dictamni extract, Herba Lysimachiae foenumgraeci extract, Tribulus terrestris or Jojoba leaf extract, the bioactive ingredients are epidermal growth factor, oligopeptides -1, fermentation of bacillus product, acetyl group Tetrapeptide -2, acetyl group hexapeptide -1, palmityl tripeptides, copper peptide, carnosine, aminobutyric acid or papain, the skin nursing at It is divided into aurantiamarin, milk protein, acetyl group hexapeptide -1, fermentation of bacillus product, sodium lauroyl glutamate, acetylation hyalomitome Sour sodium, ceramide, coco betaine, salicylic acid, lactic acid, hydroxyacetic acid, glutathione, SOD, Co-Q10, niacinamide, Tocopherol and derivative, retinol and derivative, ascorbic acid and derivative, trehalose, carbohydrate isomer, saualane, Shea butter, ferulic acid, collagen, glycosylglycerol, caffeine, tetrahydro methylpyrimidine carboxylic acid, bisabolol, milk thistle Element, resveratrol, phytosterol or astaxanthin；

Protide in the freeze-drying skin sense agent is soluble glycoprotein, collagen or gelatin hydrolysate, and the polysaccharide is poly- for fruit Sugar, xanthan gum, Sodium Hyaluronate, polyglutamic acid, carbohydrate isomer, tremella polysaccharides or trehalose, the polyalcohol are third Glycol, glycerol, butanediol or pungent glycol, described natural and synthetic oil lipid are vaseline, oleyl alcohol, caprylic/capric triglyceride or Hydrogenated palm oil, the high molecular polymerization species are Sodium Polyacrylate or carbomer, and the surfactant is that Natrulon H-10 is sweet Grease, Natrulon H-10-stearate, polysorbate80, coco betaine, sodium lauroyl glutamate or fatty acid amide Alkyl betaine.

12. the dry towel as described in any one of claim 8-11, which is characterized in that process by the following method:

Step 3: being coated on scrim surfaces, -50 DEG C~-30 DEG C freeze-dryings；

Or it processes by the following method:

Step 1: freeze-drying effect object and/or freeze-drying skin sense agent being dissolved or dispersed in water or other solution, lyophilized fibronectin is sprayed at Dimension table face mutually infiltrates, -50 DEG C~-30 DEG C freeze-dryings with freeze-drying fiber；

Step 2: freeze-drying film and composite for base fabric；

Or it processes by the following method:

Step 1: freeze-drying effect object and/or freeze-drying skin sense agent being dissolved or dispersed in water or other solution, base fabric table is sprayed on Face, -50 DEG C~-30 DEG C freeze-dryings；

Step 2: being compounded to form finished product with release layer；

Or it processes by the following method:

Step 1: freeze-drying fiber being added into water or aqueous solution, after -50 DEG C~-30 DEG C freeze-dryings, is carried out with base fabric blended compound；

Step 2: being compounded to form finished product with release layer.

13. dry towel described in any one of claim 1-11, which is characterized in that the dry towel is contacted with water, freeze-drying film layer dissolution Or dissolution, then when being in contact or rub with epidermis, the freeze-drying film layer and base fabric carrier layer removing, on epidermis at Film.

14. dry towel described in any one of claim 1-11 is as skincare product, makeup removing cleaning supplies, Transdermal absorption external plaster The application of piece or Wound dressing patch.

15. including the packaging of the dry towel as described in any one of claim 1-11.

16. a kind of freeze-drying film layer being formed in lyophilized form in base fabric carrier layer, which is characterized in that the freeze-drying film layer includes Be lyophilized effect object and/or freeze-drying skin sense agent and/or freeze-drying fiber group ingredient, wherein freeze-drying effect object selected from western medicine composition, One of traditional Chinese medicine ingredients, natural extract, bioactive ingredients, skin nursing beneficiating ingredient or combination, the freeze-drying skin sense Agent is selected from protide, polysaccharide and its esters, high molecular polymerization species, polyalcohols, natural and synthetic oil lipid, surfactant One of class or combination, the freeze-drying fiber are collagen fabric, chitin fiber, seaweed salt fiber, frustule blending fibre One of dimension, carboxymethyl cellulose fiber or combination.

17. freeze-drying film layer as claimed in claim 16, which is characterized in that when the freeze-drying film layer includes freeze-drying effect object, freezes When dry skin sense agent and freeze-drying fiber, wherein the mass ratio of freeze-drying effect object, freeze-drying skin sense agent and freeze-drying fiber is (1- 30): (0.1-50): (0.1-100)；

18. freeze-drying film layer as claimed in claim 16, which is characterized in that the western medicine composition in freeze-drying effect object is ketone Lip river Sweet smell, brufen, naphazoline, DICLOFENAC DIETHYLAMINE, ketoconazole, hydrocortisone, Miconazole clobetasol, QUMIXIN, Benzenediol, the traditional Chinese medicine ingredients are borneol, peppermint, camphor, Radix Glycyrrhizae, radix scutellariae, turmeric, rheum officinale, sulphur, kuh-seng, frutus cnidii, Huang Company, Cortex Phellodendri, calamine, zinc oxide, the natural extract is orange peel glucoside extract, Canadian Acer palmatum ' Atropurpureum' extract, scutellariae,radix mention Object, soapberry extract, fatty acid amide alkyl betaine, Gotu Kola P.E, acerola concentrate extract, Peony Root is taken to extract It is object, Flos Nelumbinis extract, Saussurea involucrata extract, ginseng root extract, the extraction of cucumber fruit, Folium Aloe extract, purslane extract, sweet Wild marjoram leaf extract, elderberry extract, rose extract, marine algae extract, truffle extract, Cordyceps extract, west Safflower extract, dried tremella extract, angelica extract, Schisandra chinens P.E, german chamomile flower extract, camellia flower extract, Rhizoma Atractylodis Macrocephalae Extract, Notogineng Extract, ginger-root extract, bletilla striata extract, Cortex Dictamni extract, Herba Lysimachiae foenumgraeci extract, tribulus terrestris extract Object or Jojoba leaf extract, the bioactive ingredients are epidermal growth factor, oligopeptides -1, fermentation of bacillus product, second Acyl group tetrapeptide -2, acetyl group hexapeptide -1, palmityl tripeptides, copper peptide, carnosine, aminobutyric acid or papain, the skin shield Reason ingredient is that aurantiamarin, milk protein, acetyl group hexapeptide -1, fermentation of bacillus product, sodium lauroyl glutamate, acetylation are saturating Bright matter acid sodium, ceramide, coco betaine, salicylic acid, lactic acid, hydroxyacetic acid, glutathione, SOD, Co-Q10, nicotinoyl Amine, tocopherol and derivative, retinol and derivative, ascorbic acid and derivative, trehalose, carbohydrate isomer, spiny dogfish Alkane, shea butter, ferulic acid, collagen, glycosylglycerol, caffeine, tetrahydro methylpyrimidine carboxylic acid, bisabolol, powder-refining with water Silibin, resveratrol, phytosterol or astaxanthin；

Protide in the freeze-drying skin sense agent is soluble glycoprotein, collagen or gelatin hydrolysate, and the polysaccharide is poly- for fruit Sugar, xanthan gum, Sodium Hyaluronate, polyglutamic acid, carbohydrate isomer, tremella polysaccharides or trehalose, the polyalcohol are third Glycol, glycerol, butanediol or pungent glycol, described natural and synthetic oil lipid are vaseline, oleyl alcohol, caprylic/capric triglyceride or Hydrogenated palm oil, the high molecular polymerization species are Sodium Polyacrylate, sodium alginate or carbomer, and the surfactant is poly- - 10 glyceride of glycerol, Natrulon H-10-stearate, polysorbate80, coco betaine, sodium lauroyl glutamate or rouge Fat acid amido alkyl betaine.

19. such as the described in any item freeze-drying film layers of claim 16-18, which is characterized in that prepared by following steps:

3:-50 DEG C~-30 DEG C of step freeze-dryings；

Or it processes by the following method:

Step 3: said mixture is sprayed at freeze-drying fiber surface or is mutually infiltrated with freeze-drying fiber, -50 DEG C~-30 DEG C freezings It is dry；

Or it processes by the following method:

20. a kind of processing method of dry towel, comprising the following steps:

Step 3: being coated on scrim surfaces, -50 DEG C~-30 DEG C freeze-dryings；

Or it processes by the following method:

Step 2: freeze-drying film and composite for base fabric；

Or it processes by the following method:

Step 2: being compounded to form finished product with release layer；

Or it processes by the following method:

Step 2: being compounded to form finished product with release layer.

21. the processing method of dry towel as claimed in claim 20, it is characterised in that:

The freeze-drying film layer includes freeze-drying effect object and/or freeze-drying skin sense agent and/or freeze-drying fiber group ingredient, wherein the jelly Do one of effect object in western medicine composition, traditional Chinese medicine ingredients, natural extract, bioactive ingredients, skin nursing beneficiating ingredient Kind or combination, the freeze-drying skin sense agent be selected from protide, polysaccharide and its esters, high molecular polymerization species, polyalcohols, naturally and One of synthetic oil lipid, surfactant-based or combination, the freeze-drying fiber be collagen fabric, chitin fiber, One of seaweed salt fiber, frustule blended fiber, carboxymethyl cellulose fiber or combination.

22. the processing method of dry towel as claimed in claim 21, which is characterized in that the western medicine composition in freeze-drying effect object For Ketoprofen, brufen, naphazoline, DICLOFENAC DIETHYLAMINE, ketoconazole, hydrocortisone, Miconazole clobetasol, bent miaow Newly, resorcinol, the traditional Chinese medicine ingredients are borneol, peppermint, camphor, Radix Glycyrrhizae, radix scutellariae, turmeric, rheum officinale, sulphur, kuh-seng, cnidium monnieri Son, the coptis, Cortex Phellodendri, calamine, zinc oxide, the natural extract are orange peel glucoside extract, Canadian Acer palmatum ' Atropurpureum' extract, radix scutellariae Root extract, soapberry extract, fatty acid amide alkyl betaine, Gotu Kola P.E, acerola concentrate extract, Peony Root Extract, Flos Nelumbinis extract, Saussurea involucrata extract, ginseng root extract, the extraction of cucumber fruit, Folium Aloe extract, purslane are extracted Object, sweet wild marjoram leaf extract, elderberry extract, rose extract, marine algae extract, truffle extract, cordyceps sinensis extract Object, saffron extract, dried tremella extract, angelica extract, Schisandra chinens P.E, german chamomile flower extract, camellia flower extract, Rhizoma Atractylodis Macrocephalae extract, Notogineng Extract, ginger-root extract, bletilla striata extract, Cortex Dictamni extract, Herba Lysimachiae foenumgraeci extract, tribulus terrestris Extract or Jojoba leaf extract, the bioactive ingredients are epidermal growth factor, oligopeptides -1, fermentation of bacillus production Object, acetyl group tetrapeptide -2, acetyl group hexapeptide -1, palmityl tripeptides, copper peptide, carnosine, aminobutyric acid or papain, the skin Skin nursing compositions are aurantiamarin, milk protein, acetyl group hexapeptide -1, fermentation of bacillus product, sodium lauroyl glutamate, acetyl Change Sodium Hyaluronate, ceramide, coco betaine, salicylic acid, lactic acid, hydroxyacetic acid, glutathione, SOD, Co-Q10, Niacinamide, tocopherol and derivative, retinol and derivative, ascorbic acid and derivative, trehalose, carbohydrate isomer, Saualane, shea butter, ferulic acid, collagen, glycosylglycerol, caffeine, tetrahydro methylpyrimidine carboxylic acid, bisabolol, Silymarin, resveratrol, phytosterol or astaxanthin；