WO2020164511A1 - Medicine dissolving and dispensing unit machine - Google Patents

Medicine dissolving and dispensing unit machine Download PDF

Info

Publication number
WO2020164511A1
WO2020164511A1 PCT/CN2020/074858 CN2020074858W WO2020164511A1 WO 2020164511 A1 WO2020164511 A1 WO 2020164511A1 CN 2020074858 W CN2020074858 W CN 2020074858W WO 2020164511 A1 WO2020164511 A1 WO 2020164511A1
Authority
WO
WIPO (PCT)
Prior art keywords
dissolving
dispensing
drive
medicine
movement mechanism
Prior art date
Application number
PCT/CN2020/074858
Other languages
French (fr)
Chinese (zh)
Inventor
刘伟强
陈煊
赵罗瑞斯
Original Assignee
上海螭宿医药科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 上海螭宿医药科技有限公司 filed Critical 上海螭宿医药科技有限公司
Publication of WO2020164511A1 publication Critical patent/WO2020164511A1/en

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe

Definitions

  • the embodiments of the present application relate to, but are not limited to, the field of dissolving and dispensing devices, and in particular to a dissolving and dispensing unit machine for automatic dissolution and dispensing.
  • Puncture the rubber stopper of the vial and infusion container for many times which is easy to cause the drug to splash and volatilize, causing trace long-term damage to the dispensing personnel, and may bring irreversible consequences; multiple piercing of the rubber stopper of the vial and infusion container is due to the needle When exposed to a non-sterile environment, microbes can contaminate the needle, and the contaminated microbes may cause secondary contamination with multiple punctures; in addition, some drugs are more difficult to dissolve, and conventional dissolution methods take longer to dissolve, and some drugs require special solvents. Dissolve, and then perform dissolving and dispensing operations. Moreover, manual operation is susceptible to the mental state of the operator and the speed of dispensing. Therefore, medical institutions need to innovate the dispensing method, which has been automated, efficient, and pollution-free.
  • a dissolving and dispensing unit machine includes:
  • the dissolving and dispensing device is installed on the main substrate and includes a dissolving and dispensing device and a peristaltic pump.
  • the dissolving and dispensing device includes at least one dissolving and dispensing channel, and each of the dissolving and dispensing channels includes two punctures and connecting the two The elastic infusion hose of the trocar, the peristaltic pump is arranged to squeeze the elastic infusion hose;
  • Two fixing modules are installed on the main substrate and configured to fix the medicine container, the dissolving and dispensing device is located above, and the two fixing modules are located below; or, the two fixing modules are located above, the The dissolving and dispensing device is located below;
  • the horizontal movement mechanism is configured to drive the medicine dissolving and dispensing device to move in a horizontal plane, so that the two piercers of the medicine dissolving and dispensing device correspond longitudinally with the two medicine containers fixed on at least one of the fixing modules;
  • the longitudinal movement mechanism is configured to drive one of the two fixing modules and the medicine dissolving device to move longitudinally, so that the piercing device pierces the medicine container or is separated from the medicine container.
  • the dissolving and dispensing device further includes a sub-substrate, the dissolving and dispensing device and the peristaltic pump are both mounted on the sub-substrate, the sub-substrate is movably connected to the main substrate, and the The horizontal movement mechanism is arranged to drive the auxiliary substrate to move.
  • the horizontal movement mechanism is a linear movement mechanism configured to drive the auxiliary substrate to move linearly.
  • the horizontal movement mechanism includes a transverse rail, a transverse slider, and a transverse drive module.
  • the transverse drive module and the transverse rail are mounted on the main substrate, and the transverse slider is connected to the The horizontal rail is matched, the horizontal slider is connected with the auxiliary substrate, and the horizontal driving module is configured to drive the horizontal slider to move along the horizontal rail.
  • the horizontal movement mechanism is a horizontal rotation mechanism configured to drive the auxiliary substrate to perform a horizontal rotation movement in a horizontal plane.
  • one fixing module includes a plurality of fixing units, each fixing unit is configured to fix one medicine container, and the horizontal movement mechanism is configured to drive the medicine dissolving and dispensing device to move horizontally until The two piercers of the dissolving and dispensing channel are longitudinally corresponding to the two fixing units one by one.
  • the fixing module further includes a fixing frame and a linear drive device, a plurality of the fixing units are fixed on the fixing frame and arranged linearly, and the linear drive device is configured to drive the fixing frame Linear movement.
  • the fixing module further includes a fixing frame and a rotation driving device, a plurality of the fixing units are fixed on the fixing frame and arranged in a circle, and the rotation driving device is configured to drive the fixing frame Rotational movement.
  • the linear drive device or the rotary drive device of the fixed module is wrapped by a sealing cover.
  • the longitudinal motion mechanism is configured to drive the two fixed modules to move longitudinally, the two fixed modules are located on the front side of the main substrate, and the longitudinal motion mechanism is located on the main substrate.
  • the longitudinal movement mechanism is connected to the two fixed modules through a supporting frame, a longitudinal sliding groove is provided on the main base plate, and the supporting frame passes through the longitudinal sliding groove;
  • a first hood is fixed on the rear side of the main substrate, and the first hood covers the longitudinal movement mechanism.
  • the longitudinal motion mechanism includes a first longitudinal motion mechanism and a second longitudinal motion mechanism
  • the support frame includes a first support frame and a second support frame
  • the longitudinal slide groove includes a first longitudinal motion mechanism. Groove and a second longitudinal sliding groove
  • the first longitudinal motion mechanism is connected to the first of the two fixed modules through the first supporting frame, and the first supporting frame passes through the first longitudinal direction A sliding groove
  • the second longitudinal movement mechanism is connected to a second fixed module of the two fixed modules through the second supporting frame, and the second supporting frame passes through the second longitudinal sliding groove.
  • the dissolving and dispensing device is located above the two fixed modules, and the horizontal movement mechanism is located on the rear side of the main substrate and above the longitudinal movement mechanism;
  • the first hood covers the horizontal movement mechanism, an upper part of the first hood is provided with a mounting groove, and the auxiliary base plate is connected to the horizontal movement mechanism after passing through the mounting groove.
  • a second hood is fixed on the secondary substrate, and the second hood covers the dissolving and dispensing device.
  • the dissolving and dispensing unit machine further includes a base and a rotating motor, the main substrate is rotatably connected to the base, and the rotating motor is configured to drive the main substrate to rotate relative to the base .
  • Fig. 1 is a three-dimensional schematic diagram of the front structure of a medicine dissolving and dispensing unit machine according to an embodiment of the present application;
  • FIG. 2 is a perspective schematic diagram of the rear view structure of the dissolving and dispensing unit machine according to an embodiment of the present application without the first cover and the second cover;
  • FIG. 3 is a schematic front view of the dissolving and dispensing unit machine according to an embodiment of the present application with the first cover and the second cover omitted;
  • FIG. 4 is a schematic structural diagram of a medicine dissolving and dispensing device in a medicine dissolving and dispensing unit machine according to an embodiment of the present application;
  • Fig. 5 is a schematic diagram of a three-dimensional structure of a medicine dissolving and dispensing unit machine according to an embodiment of the present application.
  • an embodiment of the present application provides a medicine dissolving and dispensing unit machine, which includes a main substrate 5, a medicine dissolving and dispensing device, two fixed modules, a horizontal movement mechanism and a longitudinal movement mechanism.
  • the dissolving and dispensing device is installed on the main substrate 5 and includes a dissolving and dispensing device 10 and a peristaltic pump.
  • the dissolving and dispensing device 10 includes at least one dissolving and dispensing channel, and each dissolving and dispensing channel includes two punctures and an elastic infusion hose connecting the two punctures.
  • the peristaltic pump is configured to squeeze the elastic infusion hose.
  • Two fixed modules are installed on the main base plate 5 and configured to fix the medicine container.
  • One of the dissolving and dispensing device and the two fixed modules is located above and the other is located below, that is, the dissolving and dispensing device is located above and the two fixed modules are located below; or, the two fixing modules are located above and the dissolving and dispensing device is located below.
  • the horizontal movement mechanism is arranged to drive the dissolving and dispensing device to move in the horizontal plane, so that the two piercers of the dissolving and dispensing device are longitudinally corresponding to the two medicine containers fixed on at least one fixed module, so that the dissolving and dispensing device or the fixed module moves longitudinally.
  • One piercing device can pierce two medicine containers respectively.
  • the longitudinal movement mechanism is arranged to drive one of the two fixed modules and the medicine dissolving device to move longitudinally, so that the piercer can pierce the medicine container or be separated from the medicine container.
  • the dissolving and dispensing device is set to puncture two medicinal containers that need to be dissolved and dispensed, and connect the two medicinal containers so that the contents of the two medicinal containers flow and mix with each other ,
  • the pump head of the peristaltic pump is set to squeeze the elastic infusion hose of the dissolving and dispensing device to drive the fluid flow in the elastic infusion hose to provide continuous power for the process of dissolving and dispensing
  • two fixed modules are installed on the main substrate The upper part is set to fix the medicine container;
  • the horizontal movement mechanism drives the dissolving and dispensing device to perform horizontal displacement, so that the vertical position of the puncture of the dissolving and dispensing device corresponds to the longitudinal direction of the fixed module;
  • the longitudinal movement mechanism drives the fixed module or drives the longitudinal movement of the dissolving and dispensing device, Move the fixed module and the puncture base toward each other so that the medicine container on the fixed module is punctured by the
  • the dissolving and dispensing unit machine provided in this embodiment does not need to repeatedly insert and extract the puncture during the dissolving and dispensing process, and can realize a fully enclosed dissolving and dispensing process, which not only reduces the labor intensity of dispensing, but also realizes automatic dispensing and improves efficiency. In addition, leakage and damage to dispensing personnel caused by leakage are avoided, and particulate pollution and secondary pollution by microorganisms are reduced or avoided.
  • the dissolving and dispensing unit machine of this embodiment is convenient to realize automatic, high-efficiency, and pollution-free dispensing.
  • the main substrate 5 may be connected to the base 1 and can be rotated relative to the base 1 under the driving of the rotating motor 31.
  • the dissolving and dispensing device may be installed on the main substrate 5 and may include the dissolving and dispensing device 10 and a peristaltic pump.
  • the dissolving and dispensing device 10 may include at least one dissolving and dispensing channel and two puncture bases 41, 42, each of the dissolving and dispensing channels may include two punctures 41, 42 and connecting two punctures.
  • the two punctures of each dissolving and dispensing channel can be installed on the two puncture bases 41, 42 respectively. In the example shown in FIG.
  • the dissolving and dispensing device 10 may include two dissolving and dispensing channels, and the two dissolving and dispensing channels may include two trocars mounted on the trocar base 41 (only shown in the figure One puncture 45), two punctures mounted on the puncture base 42 (only one of the punctures 46 is shown in the figure), and two elastic infusion hoses 43, 44 (the elastic infusion hose 43 can be Connect the piercers 45 and 46).
  • dissolving and dispensing device 10 The structure and working principle of the dissolving and dispensing device 10 are not described in detail in this application, and can refer to the Chinese patent application filed by the applicant named "Dissolving and Dispensing Device" and the application number is CN201820906668.6.
  • the peristaltic pump may include a peristaltic pump pump head and a pump head driving device.
  • the pump head driving device is configured to drive the pump head of the peristaltic pump to move to squeeze the elastic infusion hose.
  • the peristaltic pump may include two peristaltic pump heads 35, 36, and the pump head driving device may include an inner shaft 47, an outer shaft 48, an outer shaft rotation drive motor 33, and an inner shaft rotation Drive motor 34.
  • the two peristaltic pump heads 35, 36 can be arranged side by side, coaxial; the inner shaft 47 can be connected with a peristaltic pump head 36, the rotation of the inner shaft 47 can drive the connected peristaltic pump head 36 to rotate, and the outer shaft 48 can be connected to another peristaltic pump head 35.
  • the rotation of the outer shaft 48 can drive the connected peristaltic pump head 35 to rotate;
  • the inner shaft rotation drive motor 34 can be connected to the inner shaft 47, and the inner shaft rotation drive motor 34 can drive the inner shaft.
  • the shaft 47 rotates to drive the peristaltic pump head 36 connected to the inner shaft 47 to rotate;
  • the outer shaft rotation drive motor 33 can be connected to the outer shaft 48, and the outer shaft rotation drive motor 33 can drive the outer shaft 48 to rotate, thereby driving the outer shaft 48
  • the connected peristaltic pump head 35 rotates.
  • the types of the outer shaft rotation driving motor 33 and the inner shaft rotation driving motor 34 are not limited.
  • the outer shaft rotation driving motor 33 may be a hollow shaft motor, and the inner shaft 47 may pass through the outer shaft rotation driving motor 33 and the inner shaft rotation driving motor 34 When connected, the inner shaft rotation drives the motor 34 to rotate, thereby driving the peristaltic pump head 36 connected to the inner shaft 47 to rotate.
  • the inner shaft 47 and the outer shaft 48 can be arranged coaxially, and a bearing set or a roller set can be arranged between the inner shaft 47 and the outer shaft 48, so that the rotation of the inner shaft 47 and the outer shaft 48 does not affect each other.
  • the inner shaft rotation driving motor 34 and the outer shaft rotation driving motor 33 can be selected as stepping motors, so that when dissolving and dispensing liquid medicine, the medicine can be accurately sucked to realize quantitative dispensing.
  • At least one pump head of the peristaltic pump may be provided, which is configured to squeeze the elastic infusion hose of the dissolving and dispensing device 10 to drive the fluid flow in the elastic infusion hose to provide continuous power for the dissolution and dispensing process.
  • the peristaltic pump may include two peristaltic pump heads 35, 36, and the two peristaltic pump heads 35, 36 can squeeze two elastic infusion hoses 43, 44, respectively.
  • the dissolving and dispensing device may include other numbers of dissolving and dispensing channels, such as one or more than three (including three). The number of pump heads of the peristaltic pump can be set to one or more according to the number of dissolving and dispensing channels of the dissolving and dispensing device. More than three (including three).
  • the peristaltic pump setting may be a single-drive peristaltic pump, that is, the peristaltic pump may include a pump head driving device that can drive one pump head of the peristaltic pump to move or drive multiple pump heads of the peristaltic pump to move synchronously.
  • the peristaltic pump can be set as a multi-drive peristaltic pump according to the number of peristaltic pump pump heads, that is, each peristaltic pump pump head can correspond to a pump head drive device. In the example shown in FIG.
  • the peristaltic pump may include two pump head driving devices, and the two pump head driving devices respectively drive the two peristaltic pump pump heads 35 and 36 to move in a one-to-one correspondence.
  • the two peristaltic pump heads 35, 36 are driven by one pump head drive device, the number of pump head drive devices is reduced, the structure of the peristaltic pump is simplified, and the two peristaltic pump heads 35, 36 can be synchronized Action to simultaneously squeeze the two elastic infusion hoses 43, 44.
  • a linear peristaltic pump may be used as the power drive of the dissolving and dispensing device 10.
  • one pump head drive device or multiple pump head drive devices can be set to drive multiple peristaltic pump pump heads to move linearly synchronously or independently.
  • two fixing modules can be mounted on the main substrate 5 and configured to fix the medicine container, one of the dissolving and dispensing device and the two fixing modules is located above, and the other is located below .
  • the dissolving and dispensing device is located above two fixed modules, one of the fixed modules (the second fixed module) can be the clamping module 7, which is arranged to fix the second medicine container.
  • the type of the second medicine container is not limited, for example, it may be the infusion container 9; the other fixing module (the first fixing module) may be the bottle holding module 6, which is configured to fix the first medicine container.
  • the type of the first medicine container is not limited. Limit, for example, vial 8 and/or ampoule 54.
  • Two fixing modules can be installed on the front side of the main base plate 5 (that is, the side facing the operator's operation), so that the medicine container can be fixed to or removed from the fixed module.
  • the horizontal movement mechanism which can be installed on the main substrate 5 and connected to the dissolving and dispensing device, drives the dissolving and dispensing device to move in the horizontal plane, thereby causing the puncture on the two puncture bases 41, 42
  • the vertical positions of the devices 45 and 46 can be displaced horizontally, so that the dissolving and dispensing device corresponds to the at least one fixed module longitudinally.
  • the longitudinal movement mechanism can drive one of the two fixed modules and the dissolving and dispensing device to move longitudinally, so that the piercers 45, 46 on the two piercer bases 41, 42 pierce the medicine.
  • the container may be separated from the medicine container.
  • the longitudinal movement mechanism may include a first longitudinal movement mechanism and a second longitudinal movement mechanism.
  • the first longitudinal movement mechanism may be connected to the bottle holding module (the first fixed module) through the first receiving frame 12 ) 6 is connected, and drives the bottle holding module 6 to move up and down;
  • the second longitudinal movement mechanism can be connected to the clamping module (second fixed module) 7 through the second receiving frame 15, and drives the clamping module 7 to move up and down, so that The first medicine container on the bottle holding module 6 and the second medicine container on the clamping module 7 are respectively pierced by the piercers 45, 46 on the two piercer bases 41, 42 of the dissolving dispenser 10, or, The first medicine container on the bottle holding module 6 and the second medicine container on the clamping module 7 are separated from the piercers 45 and 46 on the two piercer bases 41 and 42 respectively.
  • the first longitudinal movement mechanism and the second longitudinal movement mechanism may be installed on the rear side of the main base plate 5, and the main base plate 5 may be provided with a first longitudinal chute through which the first supporting frame 12 can pass.
  • the first longitudinal chute, and the front end of the first receiving frame 12 can be connected with the bottle holding module 6, and the rear end can be connected with the first longitudinal movement mechanism;
  • the main substrate 5 can be provided with a second longitudinal chute, the second receiving frame
  • the frame 15 can pass through the second longitudinal chute, and the front end of the second receiving frame 15 can be connected with the clamping module 7 and the back end can be connected with the second longitudinal movement mechanism.
  • clamping module 7 The structure and working principle of the clamping module 7 are not described in detail in this application. You can refer to the Chinese patent application filed by the applicant named "Clamping Device and Dispensing Unit Machine” with application number CN201820517501.0.
  • the longitudinal movement mechanism is arranged on the rear side of the main base plate 5, and two fixed modules are arranged on the front side of the main base plate 5.
  • the dissolving and dispensing device may further include a sub-substrate 30.
  • Both the dissolving and dispensing device 10 and the peristaltic pump can be mounted on the sub-substrate 30, and the sub-substrate 30 may be combined with the main substrate.
  • the horizontal movement mechanism can drive the sub-base plate 30 to move. When the horizontal movement mechanism drives the sub-substrate 30 to move in the horizontal plane, it will drive the dissolving and dispensing device 10 and the peristaltic pump on the sub-substrate 30 to move.
  • the type of horizontal movement mechanism is not limited.
  • the horizontal movement mechanism can be a linear movement mechanism, and drives the sub-substrate 30 to move linearly, so that the horizontal movement mechanism drives the dissolving and dispensing device for horizontal displacement, so that the two puncture bases 41, 42 are
  • the vertical position of the piercers 45, 46 corresponds to the longitudinal position of the medicine container on one or two fixed modules, so that the corresponding longitudinally corresponding medicine container is pierced by the piercers 45, 46 to facilitate the dissolving and dispensing operation.
  • the horizontal movement mechanism is a linear movement mechanism.
  • the horizontal movement mechanism may include a first lateral guide rail 28, a first lateral slider 29, and a first lateral drive motor 27.
  • the first lateral drive The motor 27 and the first transverse guide rail 28 can be installed on the main substrate 5, and the first transverse guide rail 28 can be arranged parallel to the surface of the main substrate 5, and the first transverse slider 29 can cooperate with the first transverse guide rail 28.
  • the horizontal sliding block 29 may be connected to the sub-base 30, and the first horizontal driving motor 27 may drive the first horizontal sliding block 29 to move along the first horizontal guide rail 28.
  • the horizontal movement mechanism drives the dissolving and dispensing device to move horizontally.
  • the first lateral drive motor 27 of the horizontal movement mechanism drives the first lateral slider 29 to move along the first lateral guide rail 28, and then drives the dissolving and dispensing device 10 on the secondary substrate 30 to move laterally, so that the two piercings of the dissolving and dispensing device 10
  • the vertical positions of the piercers 45 and 46 on the bases 41 and 42 correspond to the two medicine containers on one or two fixed modules longitudinally.
  • the horizontal movement mechanism drives the dissolving and dispensing device 10 to move so that the piercing devices 45 and 46 on the two piercing device bases 41 and 42 of the dissolving and dispensing device 10 are vertical.
  • the position corresponds to the two first medicine containers placed on the bottle holding module 6 longitudinally, so that the first medicine container corresponding to the longitudinal direction is pierced by the piercers 45 and 46; or when the dissolving and dispensing unit machine dissolves and disperses other medicines,
  • the horizontal movement mechanism drives the dissolving and dispensing device 10 on the sub-base plate 30 to move, so that the vertical positions of the piercing devices 45 and 46 on the two piercing device bases 41 and 42 of the dissolving and dispensing device 10 are respectively aligned with the first fixed inside the bottle module 6
  • a medicine container is longitudinally corresponding to the second medicine container fixed in the clamping module 7, so that the first medicine container and the second medicine container corresponding to the longitudinal direction are pierced by the piercers 45 and 46, respectively.
  • the horizontal movement mechanism may be a horizontal rotation mechanism. Because the main substrate 5 and the auxiliary substrate 30 are movably connected, the horizontal rotation mechanism can drive the auxiliary substrate 30 to rotate horizontally, thereby driving the dissolving and dispensing device to rotate horizontally. During the dissolving and dispensing, the horizontal movement mechanism can rotate the dissolving and dispensing device 10 to an appropriate position, so that the vertical positions of the piercing devices 45 and 46 on the two piercing device bases 41 and 42 of the dissolving and dispensing device are respectively aligned with the bottle holding module 6
  • the two internally fixed first medicine containers correspond longitudinally, or respectively correspond to the first medicine container fixed in the bottle container 6 and the second medicine container fixed in the clamping module 7.
  • one of the two fixing modules may include a plurality of fixing units, and each fixing unit is configured to fix a medicine container.
  • the bottle holding module 6 may include a plurality of fixing units, and each fixing unit may be fixed with a first medicine container.
  • the first medicine container includes, but is not limited to, a medicine containing Vial 8 and Ampoule 54.
  • the dissolving and dispensing unit function can realize the dissolving and dispensing operations on the plurality of first medicine containers, which further improves the efficiency of dissolving and dispensing medicine.
  • the bottle holding module 6 may further include a fixing frame 55 and a rotation driving device.
  • a plurality of fixing units of the bottle holding module 6 may be fixed on the fixing frame 55 and present Circumferential arrangement, correspondingly, a plurality of first medicine containers can be placed on the fixed unit and arranged along the circumference.
  • the fixing frame 55 of the bottle holding module 6 can be designed in a disc shape, and 4 fixing units arranged along the circumferential direction of the disc are arranged on it.
  • the fixing unit may include a clamping and releasing mechanism to fix the vial 8 and/or ampoule.
  • Bottle 54 totals 4 bottles.
  • the clamping fixation or release of the vial 8 and/or ampoule 54 in the bottle holding module 6 can be realized by the clamping and releasing motor driving the clamping and releasing mechanism. Its structure and working mode are not described in detail in this application, please refer to the applicant The submitted Chinese patent application named "Medicine Bottle Holding Device and Method of Use", application number is CN201810603873.X. With the design of this patent application, the first medicine container clamped in the bottle holding module 6 can be rotated during the dissolution and dispensing process, thereby accelerating the dissolution of the medicine.
  • clamp release mechanisms and clamp release motors can be increased or decreased according to clinical use.
  • the first receiving frame 12 may be provided with a first receiving rod 40, and the first receiving rod 40 may be provided with a first locking mechanism 32, and a bottle
  • the module 6 can be installed on the first receiving rod 40 and can be fixed by the first locking mechanism 32, and the bottle holding module 6 can be removed from the first receiving rod 40 to facilitate cleaning and disinfection.
  • the bottle holding module 6 may further include a rotary driving device, which may be a rotary motor 39, or other driving methods such as pneumatic or hydraulic transmission to drive
  • a rotary driving device which may be a rotary motor 39, or other driving methods such as pneumatic or hydraulic transmission to drive
  • the rotation of the first receiving rod 40 drives the rotation of the bottle holding module 6 so that each first medicine holding container on the bottle holding module 6 can be longitudinally corresponding to the piercing device 45.
  • the rotating motor 39 can directly or indirectly drive the first receiving rod 40 to rotate through the transmission mechanism.
  • the first receiving rod 40 can drive the bottle holding module 6 to rotate, so that a first medicine holding container can be longitudinally connected to the piercing device 45.
  • the first longitudinal drive motor 23 of the first longitudinal movement mechanism can drive the first longitudinal slider 14 to move longitudinally along the first longitudinal guide rail 13, and the first longitudinal slider 14 can be driven and fixed in The first receiving rod 40 on the first receiving frame 12 and the bottle holding module 6 move longitudinally as a whole, so that the first medicine holding container longitudinally corresponding to the piercing device 45 is pierced by the piercing device 45; after the dissolution and dispensing is completed, the first longitudinal drive motor 23 can drive the first longitudinal sliding block 14 to move in the reverse direction along the first longitudinal guide rail 13, and drive the first receiving frame 12, the first receiving rod 40 and the bottle holding module 6 to move in reverse as a whole, so that the first medicine holding container and the puncture The device 45 is separated.
  • the bottle holding module 6 and the rotating drive device ie, the rotating motor 39
  • the rotating drive device can be wrapped in a sealed cover 2 to prevent liquid from splashing in and facilitate cleaning and disinfection.
  • the bottle holding module 6 may further include a vibration mechanism, which is configured to drive the first medicine container in the bottle holding module 6 to vibrate.
  • a vibration mechanism which is configured to drive the first medicine container in the bottle holding module 6 to vibrate.
  • the vibration mechanism drives the first medicine container to vibrate to promote the powder medicine The dissolution.
  • the setting of the vibration mechanism reduces the time required for the dissolution of the contents and improves the efficiency of dissolving and dispensing medicines.
  • a plurality of fixing units are fixed on the fixing frame 55 and arranged in a circle, a plurality of corresponding first medicine containers can be placed on the fixing unit on the fixing frame 55, and the first medicine containers are arranged in a circle.
  • the connection between the first medicine container on the fixing frame 55 and the rotating motor 39 is realized.
  • the rotating motor 39 drives the fixing frame 55 to rotate
  • the first medicine container on the fixing frame 55 is driven by the rotating motor 39 to make a corresponding rotation movement to adjust the first medicine container placed on the fixing frame 55
  • the position of the container allows the piercer to pierce the first medicine container one by one, thereby improving the efficiency of dispensing.
  • the bottle holding module 49 may include a fixing frame 56 and a linear drive device.
  • the fixing frame 56 may be installed on the first supporting frame 12 and may be perpendicular to the first supporting frame 12. With displacement in the direction of the board surface of the main substrate 5, a plurality of fixing units can be fixed on the fixing frame 56 and arranged linearly; correspondingly, a plurality of first medicine containers can be fixed on the fixing unit and arranged linearly.
  • the bottle holding module 49 can be designed to be linear, and the fixing frame 56 of the bottle holding module 49 can be provided with four fixing units arranged linearly, and the fixing unit can include a clamping release mechanism.
  • the clamping fixation or release of the vial 8 and/or ampoule 54 in the bottle holding module 49 can be realized by the clamping and releasing motor driving the clamping and releasing mechanism.
  • the structure and working principle are not described in detail in this application, please refer to the applicant The submitted Chinese patent application named "Medicine Bottle Holding Device and Method of Use", application number is CN201810603873.X.
  • the first medicine container clamped in the bottle holding module 49 can be rotated during the dissolution and dispensing process, thereby accelerating the dissolution of the medicine.
  • the number of clamping and releasing mechanisms can be increased or decreased according to clinical use.
  • the linear driving device of the bottle holding module 49 may include a second transverse rail 52, a second transverse sliding block 53, and a second transverse driving motor 50 that are matched with each other.
  • the two transverse slide blocks 53 and the second transverse drive motor 50 can be fixed on the first supporting frame 12, the second transverse guide rail 52 can be fixed on the fixing frame 56, and the second lateral drive motor 50 drives the transmission fixed on the fixing frame 56
  • the mechanism 51 laterally shifts or directly drives the second lateral sliding block 52 to displace, so that the second lateral sliding block 53 can move relative to each other along the second lateral guide rail 52, so that each first medicine container on the bottle holding module 49 can be realized
  • the piercer 45 of the dissolving and dispensing device 10 corresponds longitudinally.
  • the second transverse drive motor 50 can drive the transmission mechanism 51 fixed on the fixing frame 56 to move laterally, so that the second transverse sliding block 53 can move relatively along the second transverse guide rail 52 to make a first medicine holder
  • the container is longitudinally corresponding to the piercer 45; then, the first longitudinal drive mechanism drives the entire bottle holding module 49 to move longitudinally, so that the first medicinal container corresponding to the piercer 45 longitudinally is pierced by the piercer 45.
  • the first longitudinal drive drives the bottle-containing module 49 to move in reverse as a whole, so that the first medicine-containing container is separated from the piercing device 45.
  • the linear driving device can drive the fixing frame 56 to move linearly.
  • the linear driving device can be used to adjust the first medicine container on the fixing frame 56 to a proper position, so that the puncture device 45 pierces the first medicine container one by one, which facilitates the dissolution and dispensing operation, thereby improving Dispensing efficiency.
  • the fixing frame 56 of the bottle holding module 49 can be designed to move in a direction parallel to the surface of the main substrate 5 or at any angle to the surface of the main substrate 5 as required.
  • the second lateral drive motor 50 of the linear drive device may include a rotating motor and a transmission mechanism 51 (such as a gear-gear transmission mechanism, etc.) capable of converting rotary motion into linear movement, Or a linear motor can be included.
  • the linear motor can directly convert electrical energy into linear motion mechanical energy without any intermediate motion conversion mechanism. Therefore, the linear motor can directly drive the second horizontal slider 53 to move, and the linear motor has a simple structure and is suitable for dissolving and dispensing unit machines. Overall weight reduction.
  • the linear drive device can use other power structures such as pneumatic and hydraulic power structures to output linear or rotary motion.
  • the first longitudinal movement mechanism may include a first longitudinal guide rail 13, a first longitudinal slider 14 and a first longitudinal drive motor 23; wherein, the first longitudinal slider 14 It can be installed on the first supporting frame 12, the first longitudinal guide rail 13 is fixed on the main substrate 5, and the first longitudinal drive motor 23 is configured to drive the first longitudinal slider 14 to move along the first longitudinal guide rail 13.
  • the first longitudinal drive motor 23 can drive the first longitudinal slider 14 to move upward along the first longitudinal guide rail 13, and the first longitudinal slider 14 can pass and the first longitudinal slide
  • the first receiving frame 12 connected to the block 14 drives the bottle holding module 6 and the first medicine container to move upward, so that the first medicine container is pierced by the piercing device 45 for the dissolution and dispensing operation; when the dissolution and dispensing is completed, the first longitudinal direction
  • the driving motor 23 can drive the first longitudinal slider 14 to move downward along the first longitudinal guide rail 13, and the first longitudinal slider 14 can drive the bottle holding module 6 and the first medicine container to move downward through the first receiving frame 12, so that The first medicine container is separated from the piercing device 45.
  • the second longitudinal motion mechanism may include a second longitudinal guide rail 16, a second longitudinal slider 17, and a second longitudinal drive motor 24; wherein, the second longitudinal slider 17 may Fixed on the second supporting frame 15, the second longitudinal guide rail 16 can be fixed on the main substrate 5, and the second longitudinal drive motor 24 is arranged to drive the second longitudinal slider 17 to move along the second longitudinal guide rail 16.
  • the second longitudinal drive motor 24 can drive the second longitudinal slider 17 to move upward along the second longitudinal guide rail 16, and the second longitudinal slider 17 can pass through the second bearing connected to it.
  • the frame 15 drives the clamping module 7 and the second medicine container fixed therein to move upward, so that the second medicine container fixed on the clamping module 7 is pierced by the piercing device 46 for the dissolving and dispensing operation; when the dissolving and dispensing is completed After that, the second longitudinal drive motor 24 can drive the second longitudinal slider 17 to move downward along the second longitudinal guide rail 16, and the second longitudinal slider 17 can drive the clamping module 7 and the second medicine container through the second receiving frame 15 Move downward to separate the second medicine container from the piercer 46.
  • the longitudinal movement mechanism may be located on the rear side of the main base plate 5, the rear side of the main base plate 5 may be fixed with the first hood 3, and the first hood 3 may be Covering the longitudinal movement mechanism, on the one hand, is beneficial to prevent its parts from being exposed and prevent chemical liquid or dust pollution; on the other hand, when the longitudinal movement mechanism needs to be repaired, the first hood 3 can be removed to make the longitudinal movement mechanism effective The structure is exposed and then easy to repair.
  • the dissolving and dispensing device may be located above the two fixed modules, that is, the dissolving and dispensing device 10 may be above and the fixed module may be below.
  • the dissolving and dispensing device 10 is above, the clamping module 7 and the bottle holding module 6 are below, so the second medicine container (for example, the infusion container 9) and the first medicine container (for example, vials 8, ampoules 54, etc.) can be installed upright on the clamping module 7 and the bottle holding module 6, which on the one hand makes the installation of the infusion container 9 and the vials 8, and ampoules 54 easy, and on the other hand can avoid infusion The problem that the contents of the container 9, the vial 8, and the ampoule 54 are inverted when they leak.
  • the horizontal movement mechanism may be located on the rear side of the main base plate 5, and when the dissolving and dispensing device is located above the two fixed modules, the horizontal movement of the dissolving and dispensing device is driven.
  • the horizontal movement mechanism can be located above the longitudinal movement mechanism that drives the fixed module to move longitudinally. This arrangement is beneficial to simplify the structure of the dissolving and dispensing unit machine, and make the setting of the dissolving and dispensing unit machine reasonable.
  • the horizontal movement mechanism is located on the rear side of the main substrate 5.
  • the first hood 3 can cover the horizontal movement mechanism to prevent its parts from being exposed and prevent chemical liquid or dust pollution.
  • the upper part of the first hood 3 may be provided with a mounting groove, the sub-base 30 may pass through the mounting groove of the first hood 3 and then be connected to the horizontal movement mechanism, and the horizontal movement mechanism may be installed on the main base 5 so that the main base 5 Connect with the sub-substrate 30.
  • a second hood 4 may be fixed on the secondary substrate 30, and the second hood 4 may cover the components of the dissolving and dispensing device.
  • the second hood 4 it is beneficial to avoid dissolving and dispensing.
  • the components of the device are exposed to prevent liquid from splashing into the internal components; on the other hand, when the dissolving and dispensing device needs to be repaired, the second hood 4 can be removed to expose the dissolving and dispensing device, and then maintenance can be conveniently performed.
  • the dissolving and dispensing device may further include a dissolving and dispensing device fixing control mechanism installed on the sub-base 30.
  • the dissolving and dispensing device fixed control mechanism may include a third longitudinal movement mechanism, fixed clamp blocks 37, 38, and a moving clamp block 11.
  • the dissolving and dispensing device 10 may be mounted on the moving clamp block 11.
  • the third longitudinal movement mechanism can drive the moving clamp block 11 to reciprocate up and down, and drive the dissolving dispenser 10 to reciprocate up and down, so that the dissolving dispenser 10 can be clamped and fixed by the fixed clamp blocks 37, 38 and the moving clamp block 11.
  • the position of the puncture device 45, 46 is fixed, and the elastic infusion hose 43, 44 can be squeezed by the pump head 35, 36 of the peristaltic pump.
  • the third longitudinal movement mechanism may be located on the rear side of the secondary base plate 30, the dissolving and dispensing device 10 and the movement clamp 11 may be located on the front side of the secondary base plate 30, and the third longitudinal movement mechanism may be provided by the third receiving plate.
  • the frame 18 is connected to the movable clamp 11 of the fixed dissolving and dispensing device 10, and a third longitudinal chute can be provided on the secondary base plate 30, and the third supporting frame 18 can pass through the third longitudinal chute.
  • the front end can be connected with the movement clamping block 11, and the rear end can be connected with the third longitudinal movement mechanism.
  • the third longitudinal movement mechanism may include third longitudinal guide rails 19, 20, third longitudinal sliders 21, 22 and third longitudinal drive motors 25, 26.
  • the third longitudinal sliders 21, 22 can be fixed on the third supporting frame 18 and located at both ends of the third supporting frame 18, the third longitudinal guide rails 19, 20 can be fixed on the auxiliary base plate 30, and the third longitudinal drive motor 25 and 26 are arranged to drive the third longitudinal sliders 21 and 22 to move along the third longitudinal guide rails 19 and 20 respectively.
  • the moving clamp 11 of the fixing control mechanism of the dissolving and dispensing device may be located on the underside of the pump heads 35 and 36 of the peristaltic pump; the fixing clamping blocks 37 and 38 of the fixing and controlling mechanism of the dissolving and dispensing device may be arranged in the peristaltic respectively.
  • the two sides of the pump heads 35 and 36 correspond to each other.
  • the structure of the fixed clamp blocks 37, 38 and the moving clamp block 11 matches the structure of the dissolving and dispensing device 10 and the peristaltic pump heads 35, 36.
  • the third longitudinal drive motor 25, 26 can respectively drive the third longitudinal sliders 21, 22 to move upward along the third longitudinal guide rails 19, 20, and the third longitudinal sliders 21, 22 can drive the moving clamp block 11 toward the fixed clamp block through the third supporting frame 18 connected to it. 37 and 38 move.
  • the dissolving and dispensing device 10 touches the fixed clamping blocks 37 and 38 the dissolving and dispensing device 10 can be clamped and fixed by the fixed clamping blocks 37, 38 and the movable clamping block 11, so that the position of the piercing device 45, 46 Fixed, the peristaltic pump heads 35, 36 and the elastic infusion hoses 43, 44 can be squeezed and ready to be driven.
  • the dissolving and dispensing device 10 can be installed on the moving clamp 11 of the fixing and controlling mechanism of the dissolving and dispensing device; then, the third longitudinal drive device can drive the moving clamp 11 to move to the fixed clamping blocks 37, 38 to the dissolving and dispensing device 10. In contact with the fixed clamp blocks 37 and 38, the dissolving and dispensing device 10 is clamped and fixed by the fixed clamp blocks 37, 38 and the moving clamp block 11. The positions of the punctures 45 and 46 are fixed. At this time, the pump heads 35, 36 of the peristaltic pump and The elastic infusion hoses 43 and 44 are squeezed and to be driven.
  • the ampoule 54 is placed in the bottle holding module 6, and the opening of the ampoule 54 is upward, driving the clamping release motor of the bottle holding module 6 to clamp and position the ampoule 54 placed in the bottle holding module 6.
  • the placement and installation sequence of the dissolving and dispensing device 10, the infusion container 9 and the ampoule 54 can be interchanged.
  • the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the ampoule 54 to be coordinated and the infusion container on the bottle module 6
  • the axis of the insertion port of 9 is on the same axis.
  • the first longitudinal drive motor 23 can drive the first receiving frame 12 to move longitudinally upwards, and drive the bottle holding module 6 to move longitudinally upwards, so that the piercer 45 of the dissolving and dispensing device 10 can be inserted into the ampoule 54 to be coordinated, and The puncture device 45 is inserted into the bottom of the ampoule 54 as much as possible; subsequently or in parallel, the second longitudinal drive motor 24 can drive the second receiving frame 15 to move longitudinally upward, and then drive the infusion container 9 to move longitudinally, so that the dissolving and dispensing device The piercer 46 of 10 pierces the rubber stopper of the infusion container 9.
  • the peristaltic pump works to pump the liquid medicine in the ampoule 54 into the infusion container 9 or pump all the medicine liquid in the ampoule 54 into the infusion container 9 according to the doctor's order;
  • the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to reverse longitudinal displacement (downward displacement).
  • the two longitudinal drive motors 24 drive the second receiving frame 15 to reverse longitudinal displacement (downward displacement), so that the piercers 45 and 46 of the dissolving and dispensing device 10 are separated from the ampoule 54 and the infusion container 9 respectively, and the preparation operation is completed;
  • the rotating motor 39 can drive the first receiving rod 40 and the bottle holding module 6 to rotate, so that the The next ampoule 54 is rotated to the position to be coordinated, and then the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to move vertically upwards, so that the piercer 45 is inserted into the next ampoule 54 and the piercer 45 is inserted as far as possible The bottom of the next ampoule 54.
  • the peristaltic pump is started, and the medicine required in the next ampoule 54 is pumped into the infusion container 9 according to the doctor's order.
  • step (ii) Repeat the above step (ii) and follow the doctor's order until all the required medicines in the ampoules 54 are pumped into the infusion container 9, at which time the dissolving and dispensing process is completed.
  • the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to move downward
  • the second longitudinal drive motor 24 is used to drive the second receiving frame 15 to move downward, so that the piercing device 45, 46 is separated from the ampoule 54 and the infusion container 9 respectively, and the preparation operation is completed.
  • Step (ii) when the dissolving and dispensing unit machine shown in Figure 5 is used for this configuration operation is:
  • the first longitudinal drive motor drives the bottle holding module 49 to move downward to separate the piercer 45 from the ampoule 54; then, the second horizontal drive motor 50 drives the bottle holding module 49 Move laterally to make the bottle holding module 49 move laterally to the position of the next ampoule 54 corresponding to the longitudinal direction of the puncture; and then use the first longitudinal drive motor to drive the first receiving frame to move vertically upward, so that the puncture 45 is inserted into the next ampoule.
  • step (ii) If more than three ampoules 54 are placed in the bottle holding module 49, repeat the above step (ii) and follow the doctor's instructions until the required medicine in some ampoules 54 is pumped into the infusion container 9, and the dissolving and dispensing process is completed. .
  • the dissolving dispenser 10 can be installed on the moving clamp 11 of the fixing control mechanism of the dissolving dispenser; then, the third longitudinal drive motor 25, 26 can drive the moving clamp 11 to move to the fixed clamps 37, 38 until the dissolving The dispenser 10 is in contact with the fixed clamp blocks 37, 38, so that the dissolving dispenser 10 is clamped and fixed by the fixed clamp blocks 37, 38 and the moving clamp block 11.
  • the positions of the piercers 45, 46 are fixed, and then the peristaltic pump head 35 , 36 and the elastic infusion hose 43, 44 are squeezed and ready to be driven.
  • the placing and installation sequence of the dissolving and dispensing device 10, the infusion container 9 and the vial 8 can be interchanged.
  • the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the vial 8 on the bottle module 6 and the insertion port of the infusion container 9
  • the shaft centers are on the same axis.
  • the first longitudinal drive motor 23 can drive the first receiving frame 12 to move vertically upwards, and drive the bottle holding module 6 to move upwards longitudinally, so that the piercer 45 of the dissolving and dispensing device 10 can be inserted into the vial 8 and the piercing device 45 Insert into the bottom of the vial 8 as much as possible, or it can be set as the piercing device 45 to just pierce the rubber stopper of the vial 8; subsequently or at the same time, the second longitudinal drive motor 24 can drive the second receiving frame 15 to move vertically upward, In turn, the infusion container 9 is driven to move longitudinally upward, so that the piercer 46 of the dissolving and dispensing device 10 pierces the rubber plug of the infusion container 9.
  • the rotating motor 31 can drive the main substrate 5 to rotate, so that the rubber stopper of the vial 8 faces downward, and at the same time the outlet of the infusion container 9 faces downward, so that the liquid inside the infusion container 9 floods the needle hole of the piercer 46.
  • the peristaltic pump works to quickly pump the liquid medicine in the infusion container 10 into the vial 8 through a dissolving and dispensing channel, and then or at the same time, pump out the liquid medicine in the vial 8 through another dissolving and dispensing channel, thereby A circulating backflow state is formed between the vial 8 and the infusion container 9, and intense turbulence is formed in the vial 8, which continuously and violently disturbs the liquid and undissolved drugs in the vial 8, and is continuously and dynamically pumped through a large amount of infusion.
  • the concentration of the limited volume of the solution in the vial 8 is continuously and rapidly diluted, so that the drug dissolves faster.
  • the vial 8 can be driven to rotate, and the first longitudinal drive motor 23 can drive the first receiving frame 12 to move back and forth longitudinally, while ensuring that the needle hole of the trocar 45 is in the vial 8, so that The solution sprayed from the piercer 45 inserted into the vial 8 can cover the inner surface of the vial 8.
  • the main substrate 5 can be rotated and/or the vibration mechanism can be driven to promote the dissolution of the medicine and balance the air pressure in the vial 8 and the infusion container 9, which greatly promotes the dissolution of the insoluble medicine.
  • the main substrate 5 is rotated to the rubber stopper of the vial 5, and the liquid medicine in the vial 8 is completely pumped into the infusion container 9; If the piercing device 45 has just pierced the rubber stopper of the vial 8, the main substrate 5 is rotated until the rubber stopper of the vial 8 is down, and the liquid medicine in the vial 8 is completely pumped into the infusion container 9.
  • the first longitudinal drive motor 23 drives the bottle holding module 6 to move in the reverse longitudinal direction, and after the piercer 45 is separated from the vial 8, the rotating motor 39 can drive the first receiving rod 40 and the bottle holding module 6 to rotate, so that the bottle holding module 6 is Next, the next vial 8 rotates to the position to be coordinated; then the first longitudinal drive motor 23 drives the first receiving frame 12 to move longitudinally upward, so that the piercer 45 pierces the rubber stopper of the next vial 8; then, follow the above
  • the medicine dissolution procedure dissolves and transfers the medicine in the next vial 8 to the infusion container 9.
  • step (ii) until all the medicine in the vial 8 is dissolved and transferred to the infusion container 9, at which time the dissolving and dispensing process is completed.
  • the first longitudinal drive motor 23 is used to drive the first supporting frame 12 to move downward
  • the second longitudinal drive motor 24 is used to drive the second supporting frame 15 to move downwards, so that the piercers 45, 45, 46 is separated from the vial 8 and the infusion container 9 to complete the preparation operation. Rotate the main substrate 5 back to the original position.
  • Step (ii) when the dissolving and dispensing unit machine shown in Figure 5 is used for this configuration operation is:
  • the first longitudinal drive motor can drive the bottle holding module 49 to move downwards to separate the piercer 45 from the vial 8; then, the second lateral drive motor 50 can drive the bottle holding module 49 to move laterally, so that the bottle holding module 49 can move laterally
  • the next vial 8 corresponds to the piercing device 45 longitudinally; then the first longitudinal drive motor is used to drive the first receiving frame to move vertically upward, so that the piercing device 45 pierces the rubber stopper of the next vial 8;
  • the dispensing procedure dissolves the medicine in the next vial 8 and transfers it to the infusion container 9.
  • step (ii) until all the drugs in the vial 8 are pumped into the infusion container 9, at which time the dissolution and dispensing process is completed.
  • the dissolving dispenser 10 can be installed on the moving clamp 11 of the fixing control mechanism of the dissolving dispenser; then, the third longitudinal drive motor 25, 26 can drive the moving clamp 11 to move to the fixed clamps 37, 38 until the dissolving The dispenser 10 is in contact with the fixed clamp blocks 37, 38, so that the dissolving dispenser 10 is clamped and fixed by the fixed clamp blocks 37, 38 and the moving clamp block 11.
  • the positions of the piercers 45, 46 are fixed, and then the peristaltic pump head 35 , 36 and the elastic infusion hose 43, 44 are squeezed and ready to be driven.
  • the placing and installation sequence of the dissolving and dispensing device 10, the infusion container 9 and the vial 8 can be interchanged.
  • the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the vial 8 to be coordinated on the bottle module 6 and the infusion container
  • the axis of the insertion port of 9 is on the same axis.
  • the first longitudinal drive motor 23 can drive the first receiving frame 12 to move vertically upwards, and drive the bottle holding module 6 to move upwards longitudinally, so that the piercer 45 of the dissolving and dispensing device 10 is inserted into the vial 8, and the piercing device 45 is exhausted. Possibly inserted into the bottom of the vial 8, or it can be set as the piercing device 45 just pierced the rubber stopper of the vial 8; subsequently or at the same time, the second longitudinal drive motor 24 can drive the second receiving frame 15 to move upward in the longitudinal direction to drive The infusion container 9 moves longitudinally, so that the piercer 46 of the dissolving and dispensing device 10 pierces the rubber stopper of the infusion container 9.
  • the peristaltic pump works to pump the liquid medicine in the vial 8 into the infusion container 9 or pump all the liquid medicine in the vial 8 into the infusion container 9 according to the doctor's order.
  • the rotating motor 31 can also drive the main substrate 5 to rotate to make the rubber stopper of the vial 8 downward; then the peristaltic pump works and quantifies the medicine in the vial 8 according to the doctor’s instructions.
  • the liquid is pumped into the infusion container 9 or all the liquid medicine in the vial 8 is pumped into the infusion container 9.
  • the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to reverse longitudinal displacement (downward displacement), and the second The longitudinal drive motor 24 drives the reverse longitudinal displacement (downward displacement) of the second receiving frame 15 so that the piercers 45 and 46 of the dissolving and dispensing device 10 are separated from the vial 8 and the infusion container 9 respectively, and the preparation operation is completed;
  • the rotating motor 39 can drive the first receiving rod 40 and the bottle holding module 6 to rotate, so that the bottle holding module 6
  • the next vial 8 of the next vial 8 is rotated to be coordinated; then the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to move longitudinally upwards, so that the piercing device 45 pierces the rubber stopper of the next vial 8; according to the above dispensing procedure, Then start the peristaltic pump, and pump the medicine needed in the next vial 8 into the infusion container 9 according to the doctor's order.
  • step (ii) Repeat the above step (ii) and follow the doctor's instructions until all the required drugs in the vial 8 are transferred to the infusion container 9, at which time the dispensing process is completed.
  • the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to move downward, and the second longitudinal drive motor 24 drives the second receiving frame 15 to move downwards, so that the piercers 45 and 46 of the dissolving and dispensing device 10 are respectively Separate from the vial 8 and the infusion container 9 to complete the preparation operation.
  • Step (ii) when the dissolving and dispensing unit machine shown in Figure 5 is used for this configuration operation is:
  • the first longitudinal drive motor drives the bottle holding module 49 to move downwards to separate the piercer 45 from the vial 8; then, the second lateral drive motor 50 can drive the bottle holding module 49 to move laterally, so that the bottle holding module 49 moves laterally to The position of the next vial 8 corresponding to the longitudinal direction of the puncture 45; then the first longitudinal drive motor drives the first supporting frame to move vertically upwards, so that the puncture 45 punctures the rubber stopper of the next vial 8; then, the peristaltic pump is started , Pump the required medicinal solution in the vial 8 into the infusion container 9 according to the doctor's order.
  • step (ii) Repeat the above step (ii) and follow the doctor's instructions until all the required medicines in the vials 8 are pumped into the infusion container 9, at which time the dispensing process is completed.
  • the dissolving dispenser 10 can be installed on the moving clamp 11 of the fixing control mechanism of the dissolving dispenser; then, the third longitudinal drive motor 25, 26 can drive the moving clamp 11 to move to the fixed clamps 37, 38 until the dissolving The dispenser 10 is in contact with the fixed clamp blocks 37, 38 and clamped. At this time, the pump heads 35, 36 of the peristaltic pump and the elastic infusion hoses 43, 44 are in a squeezed and ready-to-drive state.
  • the clamping release motor of the bottle holding module 6 is driven to clamp and position the ampoule 54 and the vial 8 placed in the bottle holding module 6.
  • the dissolving and dispensing device 10 the transfusion container 9, and the ampule 54 and the vial 8 are placed and installed in an interchangeable order.
  • the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are on the bottle holding module 6 and the axis of the ampoule 54 to be coordinated and the infusion container 9 respectively.
  • the axis of the insertion port is on the same axis.
  • the first longitudinal drive motor 23 is used to drive the first supporting frame 12 to move downward
  • the second longitudinal drive motor 24 is used to drive the second supporting frame 15 to move downwards, so that the piercers 45, 45, 46 is separated from the vial 8 and the infusion container 9 to complete the preparation operation.
  • the dissolving and dispensing operation of the vial 8 can be performed first, and then the dissolving and dispensing operation of the ampoule 54; or, the vial 8 and the ampoule When 54 has multiple bottles, the dissolving and dispensing operations of the vial 8 and the ampoule 54 are alternately performed.
  • the dissolving and dispensing device 10 can be installed on the moving clamp 11; then, the third drive motor 25, 26 can drive the movable clamping block 11 to move to the fixed clamping blocks 37, 38 to the dissolving and dispensing device 10 and the fixed clamping block 37 , 38 contact, so that the dissolving and dispensing device 10 is clamped and fixed by the fixed clamp block 37, 38, and the moving clamp block 11, the position of the puncture device 45, 46 is fixed, then the peristaltic pump head 35, 36 and the elastic infusion hose 43 , 44 into squeezed and to be driven state.
  • the infusion container 10 is positioned and fixed in the clamping module 7.
  • the dissolving and dispensing device 10, the infusion container 9, and the vial 8 and the special solvent medicine bottle are placed and installed in an interchangeable order.
  • the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at the two ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the vial 8 to be coordinated and the special solvent on the bottle module 6
  • the axis of the bottle is on the same axis.
  • the first longitudinal drive motor 23 drives the first receiving frame 12 to move upwards longitudinally, and drives the bottle holding module 6 to move upwards longitudinally, so that the piercer 45 of the dissolving and dispensing device 10 is inserted into the vial 8, and the other part of the dispensing device 10 is simultaneously melted.
  • a puncture device 46 is inserted into the special solvent medicine bottle, and the puncture device 46 is inserted into the bottom of the special solvent medicine bottle as much as possible.
  • the peristaltic pump works and quickly pumps the solution in the special solvent medicine bottle into the vial 8 through a dissolving and dispensing channel; subsequently/at the same time, the liquid in the vial 8 can be pumped out to the dedicated via another dissolving and dispensing channel
  • the solvent medicine bottle forms a circulating backflow state between the vial 8 and the special solvent medicine bottle, and intense turbulence is formed in the vial 8, which continuously violently disturbs the liquid medicine and undissolved medicine in the vial, and continues through the solution
  • the concentration of the limited volume solution in the vial 8 is continuously and rapidly diluted, so that the drug dissolves faster.
  • the vial 8 can be driven to rotate, and the first longitudinal drive motor 23 can drive the first supporting frame 12 to move back and forth longitudinally, while ensuring that the needle hole of the trocar 45 is in the vial 8.
  • the needle hole of 46 is in the special solvent medicine bottle, so that the solution sprayed from the puncture device 45 inserted into the vial 8 can cover the inner surface of the vial 8.
  • the main substrate 5 can be rotated and/or the vibration mechanism can be driven, which greatly promotes the dissolution of insoluble drugs. After the medicine is completely dissolved, all the liquid medicine in the special solvent is pumped into the vial 8.
  • the first longitudinal drive motor 23 can drive the bottle holding module 6 to move downward, so that the piercers 45 and 46 are separated from the vial 8 and the special solvent medicine bottle respectively.
  • the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the vial 8 to be coordinated on the bottle module 6 and the infusion container 9
  • the axis of the insertion port is on the same axis.
  • the first longitudinal drive motor 23 can drive the first receiving frame 12 to move vertically upwards, and drive the bottle holding module 6 to move vertically upwards, so that the puncture 45 of the dissolving and dispensing device 10 is inserted into the vial 8, and the puncture 45 is exhausted.
  • the second longitudinal drive motor 24 can drive the second receiving frame 15 to move upward in the longitudinal direction to drive
  • the infusion container 9 moves longitudinally, so that the piercer 46 of the dissolving and dispensing device 10 pierces the rubber stopper of the infusion container 9.
  • the peristaltic pump works to pump the liquid medicine in the vial 8 into the infusion container 9 according to the doctor's order, or pump all the liquid medicine in the vial 8 into the infusion container 9.
  • the puncture device 45 has just pierced the rubber stopper of the vial 8
  • the main substrate 5 can also be rotated to make the rubber stopper of the vial 8 downward, and then the peristaltic pump will work to quantitatively pump the liquid medicine in the vial 8 according to the doctor’s instructions Into the infusion container 9 or pump all the liquid medicine in the vial 8 into the infusion container 9.
  • the first longitudinal drive motor 24 drives the first receiving frame 12 to reverse longitudinal displacement (downward displacement), and the second longitudinal drive motor 24 drives the second longitudinal displacement (downward) of the second receiving frame 15 Displacement), the piercers 45 and 46 of the dissolving and dispensing device 10 are separated from the vial 8 and the infusion container 9 respectively, and the compounding operation of the medicine containing the special solvent is completed.
  • the steps when the dissolving and dispensing unit machine shown in FIG. 5 is used for this configuration operation are basically the same as the steps when the dissolving and dispensing unit machine shown in FIGS. 1 to 4 is used for the preparation operation.
  • the movement of the components in the embodiments of the present application can be automatically controlled by the automatic dissolving and dispensing system.
  • the above-mentioned embodiment of the dissolving and dispensing unit machine and five examples of dissolving and dispensing medicine show that the dissolving and dispensing unit machine can quickly dissolve and dispense medicines and realize automatic dispensing, and has the function of independently dissolving medicines for each doctor's order. It can greatly improve the dissolution and preparation speed of insoluble drugs, and has the function of preparing drugs containing special solvents.
  • medical staff do not need to touch the drugs, and do not need to repeatedly puncture the rubber stopper of the infusion container and the rubber stopper of the vial, effectively reducing the separation of rubber stopper particles, external particles, and microbial contamination during the dispensing process.
  • the man-machine interface of the dissolving and dispensing unit machine of the embodiment of the application is friendly.
  • the installation operation of the dissolving and dispensing device, the installation operation of the first medicine container and the installation operation of the second medicine container are all operation-oriented For personnel, the operation is very convenient; in the dissolving and dispensing unit machine of the embodiment of the application, the main movement mechanisms that are not easy to clean and sterilize are separated from the dissolving and dispensing device, the first medicine container and the second medicine container on the main substrate and Both sides of the sub-base plate are installed, and the movement mechanism is closed, so that the dissolving and dispensing unit machine of the embodiment of the present application is easy to clean and disinfect.
  • the dissolving and dispensing unit machine of the embodiment of the application realizes automatic, high-efficiency, and pollution-free dispensing. While protecting the health of medical staff and patients, it greatly reduces the labor intensity of medical staff and can bring greater impact to society and patients benefit.
  • the terms “upper”, “lower”, “front”, “rear”, etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for ease of description
  • the embodiments and simplified descriptions of the present application do not indicate or imply that the structure referred to has a specific orientation, is constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the embodiments of the present application.
  • connection can be a fixed connection, a detachable connection, or an integral connection; Connect directly or indirectly through an intermediary.
  • connection can be a fixed connection, a detachable connection, or an integral connection; Connect directly or indirectly through an intermediary.

Abstract

Disclosed is a medicine dissolving and dispensing unit machine used for automatically dissolving and dispensing a medicine, the machine comprising: a main base plate (5), a medicine dissolving and dispensing apparatus, two fixing modules, a horizontal movement mechanism, and a longitudinal movement mechanism, wherein the medicine dissolving and dispensing apparatus is mounted on the main base plate (5), and comprises a medicine dissolving and dispensing device (10) and a peristaltic pump; the medicine dissolving and dispensing device (10) comprises at least one medicine dissolving and dispensing channel; each medicine dissolving and dispensing channel comprises two puncture devices (41, 42) and elastic transfusion pipes (43, 44), which connect the two puncture devices (41, 42); and the peristaltic pump is configured to squeeze the elastic transfusion pipes (43, 44). The two fixing modules are mounted on the main base plate (5), and are configured to have medicine-holding containers fixed thereon; the horizontal movement mechanism is configured to drive the medicine dissolving and dispensing apparatus to move in a horizontal plane such that the two puncture devices (41, 42) of the medicine dissolving and dispensing apparatus longitudinally correspond to the two medicine-holding containers fixed on at least one of the fixing modules; and the longitudinal movement mechanism is configured to drive either the two fixing modules or the medicine dissolving and dispensing apparatus to move longitudinally such that the puncture devices (41, 42) puncture the medicine-holding containers or are separated from the medicine-holding containers.

Description

一种溶配药单元机Dissolving and dispensing unit machine 技术领域Technical field
本申请实施例涉及但不限于溶配药器械领域,特别涉及一种用于自动溶配药的溶配药单元机。The embodiments of the present application relate to, but are not limited to, the field of dissolving and dispensing devices, and in particular to a dissolving and dispensing unit machine for automatic dissolution and dispensing.
背景技术Background technique
目前,医院配制静脉输液用药物的模式主要有两种,一种是在静脉药物配置中心(PIVAS,Pharmacy Intravenous Admixture Services)集中配制,一种是在急诊或病房临时配制。但两种配制模式大多通过医护人员人工操作进行,在配药的过程中,不能连续配制,效率低,速度慢,劳动强度大。此外,在配制西林瓶装的药品时,由于多次穿刺西林瓶及输液容器的胶塞,容易造成漏液及微粒污染;在配制细胞毒性药物、化疗药物、易致敏药物、高活性等药物时,多次穿刺西林瓶及输液容器的胶塞,易产生药物溅出和挥发,对配药人员造成微量长期伤害,可能带来不可逆的后果;多次穿刺西林瓶及输液容器的胶塞,由于针头暴露在非无菌环境,微生物会污染针头,污染的微生物可能会随着多次穿刺造成二次污染;此外,有些药物比较难溶,常规溶解方法溶解时间较长,有些药品需要使用专用溶媒进行溶解,然后再进行溶配药操作。而且,人工操作易受到操作人员精神状态和配药速度的影响,因此医疗机构需要配药方式的革新,以迄自动化、高效率、无污染的配药方式出现。At present, there are mainly two modes for preparing intravenous infusion drugs in hospitals. One is centralized preparation in the intravenous drug allocation center (PIVAS, Pharmacy Intravenous Admixture Services), and the other is temporary preparation in the emergency department or ward. However, the two preparation modes are mostly carried out manually by medical staff. During the dispensing process, continuous preparation is not possible, resulting in low efficiency, slow speed and high labor intensity. In addition, when preparing medicines in vials, it is easy to cause leakage and particle contamination due to multiple punctures of the rubber stoppers of the vials and infusion containers; when preparing cytotoxic drugs, chemotherapeutics, allergenic drugs, high-activity drugs, etc. Puncture the rubber stopper of the vial and infusion container for many times, which is easy to cause the drug to splash and volatilize, causing trace long-term damage to the dispensing personnel, and may bring irreversible consequences; multiple piercing of the rubber stopper of the vial and infusion container is due to the needle When exposed to a non-sterile environment, microbes can contaminate the needle, and the contaminated microbes may cause secondary contamination with multiple punctures; in addition, some drugs are more difficult to dissolve, and conventional dissolution methods take longer to dissolve, and some drugs require special solvents. Dissolve, and then perform dissolving and dispensing operations. Moreover, manual operation is susceptible to the mental state of the operator and the speed of dispensing. Therefore, medical institutions need to innovate the dispensing method, which has been automated, efficient, and pollution-free.
发明概述Summary of the invention
以下是对本文详细描述的主题的概述。本概述并非是为了限制权利要求的保护范围。The following is an overview of the topics detailed in this article. This summary is not intended to limit the scope of protection of the claims.
一种溶配药单元机,包括:A dissolving and dispensing unit machine includes:
主基板;Main substrate
溶配药装置,安装在所述主基板上,包括溶配药器和蠕动泵,所述溶配 药器包括至少一个溶配药通道,每一个所述溶配药通道包括两个穿刺器和连接所述两个穿刺器的弹性输液软管,所述蠕动泵设置成挤压所述弹性输液软管;The dissolving and dispensing device is installed on the main substrate and includes a dissolving and dispensing device and a peristaltic pump. The dissolving and dispensing device includes at least one dissolving and dispensing channel, and each of the dissolving and dispensing channels includes two punctures and connecting the two The elastic infusion hose of the trocar, the peristaltic pump is arranged to squeeze the elastic infusion hose;
两个固定模块,安装在所述主基板上,设置成固定盛药容器,所述溶配药装置位于上方,所述两个固定模块位于下方;或者,所述两个固定模块位于上方,所述溶配药装置位于下方;Two fixing modules are installed on the main substrate and configured to fix the medicine container, the dissolving and dispensing device is located above, and the two fixing modules are located below; or, the two fixing modules are located above, the The dissolving and dispensing device is located below;
水平运动机构,设置成带动所述溶配药装置在水平面内运动,使所述溶配药装置的所述两个穿刺器与至少一个所述固定模块上固定的两个所述盛药容器纵向对应;和The horizontal movement mechanism is configured to drive the medicine dissolving and dispensing device to move in a horizontal plane, so that the two piercers of the medicine dissolving and dispensing device correspond longitudinally with the two medicine containers fixed on at least one of the fixing modules; with
纵向运动机构,设置成带动所述两个固定模块和所述溶配药装置中的一者纵向移动,使所述穿刺器穿刺所述盛药容器或与所述盛药容器分离。The longitudinal movement mechanism is configured to drive one of the two fixing modules and the medicine dissolving device to move longitudinally, so that the piercing device pierces the medicine container or is separated from the medicine container.
一些示例性实施例中,所述溶配药装置还包括副基板,所述溶配药器和所述蠕动泵均安装在所述副基板上,所述副基板与所述主基板活动连接,所述水平运动机构设置成带动所述副基板运动。In some exemplary embodiments, the dissolving and dispensing device further includes a sub-substrate, the dissolving and dispensing device and the peristaltic pump are both mounted on the sub-substrate, the sub-substrate is movably connected to the main substrate, and the The horizontal movement mechanism is arranged to drive the auxiliary substrate to move.
一些示例性实施例中,所述水平运动机构为线性移动机构,设置成带动副基板直线移动。In some exemplary embodiments, the horizontal movement mechanism is a linear movement mechanism configured to drive the auxiliary substrate to move linearly.
一些示例性实施例中,所述水平运动机构包括横向导轨、横向滑块和横向驱动模块,所述横向驱动模块和所述横向导轨安装在所述主基板上,所述横向滑块与所述横向导轨配合,所述横向滑块与所述副基板连接,所述横向驱动模块设置成驱动所述横向滑块沿所述横向导轨运动。In some exemplary embodiments, the horizontal movement mechanism includes a transverse rail, a transverse slider, and a transverse drive module. The transverse drive module and the transverse rail are mounted on the main substrate, and the transverse slider is connected to the The horizontal rail is matched, the horizontal slider is connected with the auxiliary substrate, and the horizontal driving module is configured to drive the horizontal slider to move along the horizontal rail.
一些示例性实施例中,所述水平运动机构为水平旋转机构,设置成带动所述副基板在水平面内进行水平旋转运动。In some exemplary embodiments, the horizontal movement mechanism is a horizontal rotation mechanism configured to drive the auxiliary substrate to perform a horizontal rotation movement in a horizontal plane.
一些示例性实施例中,一个所述固定模块包括多个固定单元,每一个所述固定单元设置成固定一个所述盛药容器,所述水平运动机构设置成带动所述溶配药装置水平运动直至所述溶配药通道的两个穿刺器与两个所述固定单元一一纵向对应。In some exemplary embodiments, one fixing module includes a plurality of fixing units, each fixing unit is configured to fix one medicine container, and the horizontal movement mechanism is configured to drive the medicine dissolving and dispensing device to move horizontally until The two piercers of the dissolving and dispensing channel are longitudinally corresponding to the two fixing units one by one.
一些示例性实施例中,所述固定模块还包括固定架和线性驱动装置,多个所述固定单元固定在所述固定架上且呈线性排列,所述线性驱动装置设置 成驱动所述固定架线性移动。In some exemplary embodiments, the fixing module further includes a fixing frame and a linear drive device, a plurality of the fixing units are fixed on the fixing frame and arranged linearly, and the linear drive device is configured to drive the fixing frame Linear movement.
一些示例性实施例中,所述固定模块还包括固定架和旋转驱动装置,多个所述固定单元固定在所述固定架上且呈圆周排列,所述旋转驱动装置设置成驱动所述固定架旋转运动。In some exemplary embodiments, the fixing module further includes a fixing frame and a rotation driving device, a plurality of the fixing units are fixed on the fixing frame and arranged in a circle, and the rotation driving device is configured to drive the fixing frame Rotational movement.
一些示例性实施例中,所述固定模块的线性驱动装置或旋转驱动装置被密封罩包裹。In some exemplary embodiments, the linear drive device or the rotary drive device of the fixed module is wrapped by a sealing cover.
一些示例性实施例中,所述纵向运动机构设置成带动所述两个固定模块纵向移动,所述两个固定模块位于所述主基板的前侧,所述纵向运动机构位于所述主基板的后侧,所述纵向运动机构通过承接架与所述两个固定模块连接,所述主基板上设有纵向滑槽,所述承接架穿过所述纵向滑槽;In some exemplary embodiments, the longitudinal motion mechanism is configured to drive the two fixed modules to move longitudinally, the two fixed modules are located on the front side of the main substrate, and the longitudinal motion mechanism is located on the main substrate. On the rear side, the longitudinal movement mechanism is connected to the two fixed modules through a supporting frame, a longitudinal sliding groove is provided on the main base plate, and the supporting frame passes through the longitudinal sliding groove;
所述主基板的后侧固定有第一机罩,所述第一机罩罩住所述纵向运动机构。一些示例性实施例中,所述纵向运动机构包括第一纵向运动机构和第二纵向运动机构,所述承接架包括第一承接架和第二承接架,所述纵向滑槽包括第一纵向滑槽和第二纵向滑槽,所述第一纵向运动机构通过所述第一承接架与所述两个固定模块中的第一固定模块连接,所述第一承接架穿过所述第一纵向滑槽,所述第二纵向运动机构通过所述第二承接架与所述两个固定模块中的第二固定模块连接,所述第二承接架穿过所述第二纵向滑槽。A first hood is fixed on the rear side of the main substrate, and the first hood covers the longitudinal movement mechanism. In some exemplary embodiments, the longitudinal motion mechanism includes a first longitudinal motion mechanism and a second longitudinal motion mechanism, the support frame includes a first support frame and a second support frame, and the longitudinal slide groove includes a first longitudinal motion mechanism. Groove and a second longitudinal sliding groove, the first longitudinal motion mechanism is connected to the first of the two fixed modules through the first supporting frame, and the first supporting frame passes through the first longitudinal direction A sliding groove, the second longitudinal movement mechanism is connected to a second fixed module of the two fixed modules through the second supporting frame, and the second supporting frame passes through the second longitudinal sliding groove.
一些示例性实施例中,所述溶配药装置位于所述两个固定模块的上方,所述水平运动机构位于所述主基板的后侧、所述纵向运动机构的上方;In some exemplary embodiments, the dissolving and dispensing device is located above the two fixed modules, and the horizontal movement mechanism is located on the rear side of the main substrate and above the longitudinal movement mechanism;
所述第一机罩罩住所述水平运动机构,所述第一机罩的上部设有安装槽,所述副基板穿过所述安装槽后与所述水平运动机构连接。The first hood covers the horizontal movement mechanism, an upper part of the first hood is provided with a mounting groove, and the auxiliary base plate is connected to the horizontal movement mechanism after passing through the mounting groove.
一些示例性实施例中,所述副基板上固定有第二机罩,所述第二机罩罩住所述溶配药装置。In some exemplary embodiments, a second hood is fixed on the secondary substrate, and the second hood covers the dissolving and dispensing device.
一些示例性实施例中,所述溶配药单元机还包括基座和旋转电机,所述主基板与所述基座转动连接,所述旋转电机设置成驱动所述主基板相对所述基座旋转。In some exemplary embodiments, the dissolving and dispensing unit machine further includes a base and a rotating motor, the main substrate is rotatably connected to the base, and the rotating motor is configured to drive the main substrate to rotate relative to the base .
在阅读并理解了附图概述和本申请实施例的实施方式后,可以明白其他方面。After reading and understanding the summary of the drawings and the implementation of the embodiments of the present application, other aspects can be understood.
附图概述Figure overview
图1是根据本申请实施例的溶配药单元机的前视结构的立体示意图;Fig. 1 is a three-dimensional schematic diagram of the front structure of a medicine dissolving and dispensing unit machine according to an embodiment of the present application;
图2是根据本申请实施例的溶配药单元机省去第一机罩和第二机罩后的后视结构的立体示意图;2 is a perspective schematic diagram of the rear view structure of the dissolving and dispensing unit machine according to an embodiment of the present application without the first cover and the second cover;
图3是根据本申请实施例的溶配药单元机省去第一机罩和第二机罩后的主视结构示意图;3 is a schematic front view of the dissolving and dispensing unit machine according to an embodiment of the present application with the first cover and the second cover omitted;
图4是根据本申请实施例的溶配药单元机中的溶配药装置的结构示意图;4 is a schematic structural diagram of a medicine dissolving and dispensing device in a medicine dissolving and dispensing unit machine according to an embodiment of the present application;
图5是根据本申请实施例的溶配药单元机的立体结构示意图。Fig. 5 is a schematic diagram of a three-dimensional structure of a medicine dissolving and dispensing unit machine according to an embodiment of the present application.
其中,图1至图5中附图标记与部件名称之间的关系为:Among them, the relationship between the reference signs and component names in Figures 1 to 5 is:
1-基座;2-密封罩;3-第一机罩;4-第二机罩;5-主基板;6-盛瓶模块;7-夹持模块;8-西林瓶;9-输液容器;10-溶配药器;11-运动夹块;12-第一承接架;13-第一纵向导轨;14-第一纵向滑块;15-第二承接架;16-第二纵向导轨;17-第二纵向滑块;18-第三承接架;19、20-第三纵向导轨;21、22-第三纵向滑块;23-第一纵向驱动电机;24-第二纵向驱动电机;25、26-第三纵向驱动电机;27-第一横向驱动电机;28-第一横向导轨;29-第一横向滑块;30-副基板;31-旋转电机;32-第一卡锁机构;33-外轴旋转驱动电机;34-内轴旋转驱动电机;35、36-蠕动泵泵头;37、38-固定夹块;39-旋转电机;40-第一承接杆;41、42-穿刺器基座;43、44-弹性输液软管;45、46-穿刺器;47-内轴;48-外轴;49-盛瓶模块;50-第二横向驱动电机;51-传动机构;52-第二横向导轨;53-第二横向滑块;54-安瓿瓶;55、56-固定架。1- Base; 2- Sealing cover; 3- First machine cover; 4- Second machine cover; 5- Main substrate; 6- Bottle holding module; 7- Clamping module; 8- Cillin bottle; 9- Infusion container 10-Dissolving medicine dispenser; 11-moving clamp block; 12-first receiving frame; 13-first longitudinal rail; 14-first longitudinal sliding block; 15-second receiving frame; 16-second longitudinal rail; 17 -The second longitudinal slide; 18- the third supporting frame; 19, 20- the third longitudinal guide rail; 21, 22- the third longitudinal slide; 23- the first longitudinal drive motor; 24- the second longitudinal drive motor; 25 , 26-third longitudinal drive motor; 27-first lateral drive motor; 28-first lateral guide rail; 29-first lateral slide; 30-sub-base plate; 31-rotating motor; 32-first locking mechanism; 33-Outer shaft rotating drive motor; 34-Inner shaft rotating drive motor; 35,36-Peristaltic pump pump head; 37,38-Fixed clamp block; 39-Rotating motor; 40-First receiving rod; 41,42-puncture Base; 43, 44- elastic infusion hose; 45, 46- puncture; 47- inner shaft; 48- outer shaft; 49- bottle holding module; 50- second transverse drive motor; 51- transmission mechanism; 52 -The second transverse guide rail; 53-The second transverse slider; 54-Ampoule; 55,56-fixed frame.
详述Detail
下文中将结合附图对本申请实施例进行详细说明。需要说明的是,在不冲突的情况下,本申请中的实施例及实施例中的特征可以相互任意组合。Hereinafter, the embodiments of the present application will be described in detail with reference to the drawings. It should be noted that the embodiments in this application and the features in the embodiments can be combined with each other arbitrarily if there is no conflict.
在下面的描述中阐述了很多实施方式以便于充分理解本申请实施例,但是,本申请实施例还可以采用其他不同于在此描述的方式来实施,因此,本申请实施例的保护范围并不受下面公开的实现方式的限制。In the following description, many implementation manners are described in order to fully understand the embodiments of this application. However, the embodiments of this application can also be implemented in other ways different from those described here. Therefore, the protection scope of the embodiments of this application is not Limited by the implementation methods disclosed below.
如图1至图4所示,本申请实施例提供了一种溶配药单元机,包括:主基板5、溶配药装置、两个固定模块、水平运动机构和纵向运动机构。As shown in Figs. 1 to 4, an embodiment of the present application provides a medicine dissolving and dispensing unit machine, which includes a main substrate 5, a medicine dissolving and dispensing device, two fixed modules, a horizontal movement mechanism and a longitudinal movement mechanism.
溶配药装置安装在主基板5上,包括溶配药器10和蠕动泵。溶配药器10包括至少一个溶配药通道,每一个溶配药通道包括两个穿刺器和连接两个穿刺器的弹性输液软管。蠕动泵设置成挤压弹性输液软管。The dissolving and dispensing device is installed on the main substrate 5 and includes a dissolving and dispensing device 10 and a peristaltic pump. The dissolving and dispensing device 10 includes at least one dissolving and dispensing channel, and each dissolving and dispensing channel includes two punctures and an elastic infusion hose connecting the two punctures. The peristaltic pump is configured to squeeze the elastic infusion hose.
两个固定模块安装在主基板5上,设置成固定盛药容器。溶配药装置和两个固定模块中的一者位于上方,另一者位于下方,即溶配药装置位于上方,两个固定模块位于下方;或者,两个固定模块位于上方,溶配药装置位于下方。Two fixed modules are installed on the main base plate 5 and configured to fix the medicine container. One of the dissolving and dispensing device and the two fixed modules is located above and the other is located below, that is, the dissolving and dispensing device is located above and the two fixed modules are located below; or, the two fixing modules are located above and the dissolving and dispensing device is located below.
水平运动机构设置成带动溶配药装置在水平面内运动,使溶配药装置的两个穿刺器与至少一个固定模块上固定的两个盛药容器纵向对应,以便溶配药装置或固定模块纵向移动后两个穿刺器能够分别刺穿两个盛药容器。The horizontal movement mechanism is arranged to drive the dissolving and dispensing device to move in the horizontal plane, so that the two piercers of the dissolving and dispensing device are longitudinally corresponding to the two medicine containers fixed on at least one fixed module, so that the dissolving and dispensing device or the fixed module moves longitudinally. One piercing device can pierce two medicine containers respectively.
纵向运动机构设置成带动两个固定模块和溶配药装置中的一者纵向移动,使穿刺器可穿刺盛药容器或与盛药容器分离。The longitudinal movement mechanism is arranged to drive one of the two fixed modules and the medicine dissolving device to move longitudinally, so that the piercer can pierce the medicine container or be separated from the medicine container.
本实施例提供的溶配药单元机,溶配药器设置成穿刺需要进行溶配药的两个盛药容器,并将两个盛药容器连通,以便两个盛药容器内的内容物互相流动、混合,进行溶配药;蠕动泵的泵头设置成挤压溶配药器的弹性输液软管,驱动弹性输液软管内的流体流动,为溶配药过程提供持续的动力;两个固定模块安装在主基板上,设置成固定盛药容器;水平运动机构驱动溶配药装置进行水平位移,使溶配药器的穿刺器的垂直位置与固定模块纵向对应;纵向运动机构带动固定模块或者带动溶配药器纵向运动,使固定模块和穿刺器基座相向运动,以便固定模块上的盛药容器被穿刺器穿刺,并且在溶配药完成后,纵向运动机构使固定模块和穿刺器相背离运动,以便盛药容器与穿刺器分离。In the dissolving and dispensing unit machine provided in this embodiment, the dissolving and dispensing device is set to puncture two medicinal containers that need to be dissolved and dispensed, and connect the two medicinal containers so that the contents of the two medicinal containers flow and mix with each other , For dissolving and dispensing; the pump head of the peristaltic pump is set to squeeze the elastic infusion hose of the dissolving and dispensing device to drive the fluid flow in the elastic infusion hose to provide continuous power for the process of dissolving and dispensing; two fixed modules are installed on the main substrate The upper part is set to fix the medicine container; the horizontal movement mechanism drives the dissolving and dispensing device to perform horizontal displacement, so that the vertical position of the puncture of the dissolving and dispensing device corresponds to the longitudinal direction of the fixed module; the longitudinal movement mechanism drives the fixed module or drives the longitudinal movement of the dissolving and dispensing device, Move the fixed module and the puncture base toward each other so that the medicine container on the fixed module is punctured by the puncture, and after the dissolution and dispensing is completed, the longitudinal movement mechanism moves the fixed module and the puncture away from each other, so that the medicine container and the puncture Separate.
本实施例提供的溶配药单元机,在溶配药过程中不需将穿刺器反复插入抽出,可实现全封闭的溶配药过程,既减轻了配药的劳动强度,又实现了自动配制,效率提高,且避免了造成漏液及漏液对配药人员造成的伤害,减少或避免了微粒污染、微生物的二次污染。本实施例的溶配药单元机便于实现自动化、高效率、无污染的配药。The dissolving and dispensing unit machine provided in this embodiment does not need to repeatedly insert and extract the puncture during the dissolving and dispensing process, and can realize a fully enclosed dissolving and dispensing process, which not only reduces the labor intensity of dispensing, but also realizes automatic dispensing and improves efficiency. In addition, leakage and damage to dispensing personnel caused by leakage are avoided, and particulate pollution and secondary pollution by microorganisms are reduced or avoided. The dissolving and dispensing unit machine of this embodiment is convenient to realize automatic, high-efficiency, and pollution-free dispensing.
在一些示例性实施例中,如图1和图2所示,主基板5可与基座1相连,并可在旋转电机31驱动下能相对基座1旋转。In some exemplary embodiments, as shown in FIGS. 1 and 2, the main substrate 5 may be connected to the base 1 and can be rotated relative to the base 1 under the driving of the rotating motor 31.
在一些示例性实施例中,溶配药装置,其可安装在主基板5上,且可包括溶配药器10和蠕动泵。In some exemplary embodiments, the dissolving and dispensing device may be installed on the main substrate 5 and may include the dissolving and dispensing device 10 and a peristaltic pump.
在一些示例性实施例中,溶配药器10可包括至少一个溶配药通道和两个穿刺器基座41、42,每一个溶配药通道可包括两个穿刺器41、42和连接两个穿刺器的弹性输液软管,每一个溶配药通道的两个穿刺器可分别安装在两个穿刺器基座41、42上。在图4所示的示例中,溶配药器10可包括两个溶配药器通道,两个溶配药通道可包括安装在穿刺器基座41上的两个穿刺器(图中仅示出了其中一个穿刺器45)、安装在穿刺器基座42上的两个穿刺器(图中仅示出了其中一个穿刺器46)、以及两个弹性输液软管43、44(弹性输液软管43可将穿刺器45、46连接)。In some exemplary embodiments, the dissolving and dispensing device 10 may include at least one dissolving and dispensing channel and two puncture bases 41, 42, each of the dissolving and dispensing channels may include two punctures 41, 42 and connecting two punctures. The two punctures of each dissolving and dispensing channel can be installed on the two puncture bases 41, 42 respectively. In the example shown in FIG. 4, the dissolving and dispensing device 10 may include two dissolving and dispensing channels, and the two dissolving and dispensing channels may include two trocars mounted on the trocar base 41 (only shown in the figure One puncture 45), two punctures mounted on the puncture base 42 (only one of the punctures 46 is shown in the figure), and two elastic infusion hoses 43, 44 (the elastic infusion hose 43 can be Connect the piercers 45 and 46).
溶配药器10的结构和工作原理不在本申请中详细描述,可参见申请人提交的名称为“溶配药器”、申请号为CN201820906668.6的中国专利申请。The structure and working principle of the dissolving and dispensing device 10 are not described in detail in this application, and can refer to the Chinese patent application filed by the applicant named "Dissolving and Dispensing Device" and the application number is CN201820906668.6.
在一些示例性实施例中,蠕动泵,其可包括蠕动泵泵头和泵头驱动装置,泵头驱动装置设置成驱动蠕动泵泵头运动,以挤压弹性输液软管。在图2和图4所示的示例中,蠕动泵可包括两个蠕动泵泵头35、36,泵头驱动装置可包括内轴47、外轴48、外轴旋转驱动电机33、内轴旋转驱动电机34。其中,两个蠕动泵泵头35、36可并排设置,同轴心;内轴47可与一个蠕动泵泵头36相连,内轴47转动可带动相连接的蠕动泵泵头36转动,外轴48可与另一个蠕动泵泵头35相连,外轴48转动可带动相连接的蠕动泵泵头35转动;内轴旋转驱动电机34可与内轴47相连,内轴旋转驱动电机34可带动内轴47转动,进而带动与内轴47相连的蠕动泵泵头36转动;外轴旋转驱动电机33可与外轴48相连,外轴旋转驱动电机33可带动外轴48转动,进而带动与外轴48相连的蠕动泵泵头35转动。In some exemplary embodiments, the peristaltic pump may include a peristaltic pump pump head and a pump head driving device. The pump head driving device is configured to drive the pump head of the peristaltic pump to move to squeeze the elastic infusion hose. In the example shown in Figures 2 and 4, the peristaltic pump may include two peristaltic pump heads 35, 36, and the pump head driving device may include an inner shaft 47, an outer shaft 48, an outer shaft rotation drive motor 33, and an inner shaft rotation Drive motor 34. Among them, the two peristaltic pump heads 35, 36 can be arranged side by side, coaxial; the inner shaft 47 can be connected with a peristaltic pump head 36, the rotation of the inner shaft 47 can drive the connected peristaltic pump head 36 to rotate, and the outer shaft 48 can be connected to another peristaltic pump head 35. The rotation of the outer shaft 48 can drive the connected peristaltic pump head 35 to rotate; the inner shaft rotation drive motor 34 can be connected to the inner shaft 47, and the inner shaft rotation drive motor 34 can drive the inner shaft. The shaft 47 rotates to drive the peristaltic pump head 36 connected to the inner shaft 47 to rotate; the outer shaft rotation drive motor 33 can be connected to the outer shaft 48, and the outer shaft rotation drive motor 33 can drive the outer shaft 48 to rotate, thereby driving the outer shaft 48 The connected peristaltic pump head 35 rotates.
外轴旋转驱动电机33和内轴旋转驱动电机34的类型不限,例如外轴旋转驱动电机33可为空心轴电机,内轴47可穿过外轴旋转驱动电机33与内轴旋转驱动电机34相连,内轴旋转驱动电机34旋转进而带动与内轴47相连的蠕动泵泵头36转动。内轴47与外轴48可同轴心设置,且内轴47与外轴48 之间可设有轴承组或滚轮组,使内轴47、外轴48的转动互不影响。内轴旋转驱动电机34和外轴旋转驱动电机33可选用步进电机,这样在进行溶配药时,在对液体药物配药时,可精确抽吸药品,实现定量配药。The types of the outer shaft rotation driving motor 33 and the inner shaft rotation driving motor 34 are not limited. For example, the outer shaft rotation driving motor 33 may be a hollow shaft motor, and the inner shaft 47 may pass through the outer shaft rotation driving motor 33 and the inner shaft rotation driving motor 34 When connected, the inner shaft rotation drives the motor 34 to rotate, thereby driving the peristaltic pump head 36 connected to the inner shaft 47 to rotate. The inner shaft 47 and the outer shaft 48 can be arranged coaxially, and a bearing set or a roller set can be arranged between the inner shaft 47 and the outer shaft 48, so that the rotation of the inner shaft 47 and the outer shaft 48 does not affect each other. The inner shaft rotation driving motor 34 and the outer shaft rotation driving motor 33 can be selected as stepping motors, so that when dissolving and dispensing liquid medicine, the medicine can be accurately sucked to realize quantitative dispensing.
蠕动泵泵头可设置至少一个,设置成挤压溶配药器10的弹性输液软管,驱动弹性输液软管内的流体流动,为溶配药过程提供持续的动力。在图4所示的示例中,蠕动泵可包括两个蠕动泵泵头35、36,两个蠕动泵泵头35、36可分别挤压两个弹性输液软管43、44。在一些示例中,溶配药器可以包括其它数量的溶配药通道,如一个或三个以上(包括三个),蠕动泵泵头的数量可以根据溶配药器的溶配药通道的数量设置为一个或三个以上(包括三个)。At least one pump head of the peristaltic pump may be provided, which is configured to squeeze the elastic infusion hose of the dissolving and dispensing device 10 to drive the fluid flow in the elastic infusion hose to provide continuous power for the dissolution and dispensing process. In the example shown in FIG. 4, the peristaltic pump may include two peristaltic pump heads 35, 36, and the two peristaltic pump heads 35, 36 can squeeze two elastic infusion hoses 43, 44, respectively. In some examples, the dissolving and dispensing device may include other numbers of dissolving and dispensing channels, such as one or more than three (including three). The number of pump heads of the peristaltic pump can be set to one or more according to the number of dissolving and dispensing channels of the dissolving and dispensing device. More than three (including three).
泵头驱动装置的个数不限。在一些示例中,蠕动泵设置可为单驱动蠕动泵,即蠕动泵可包括一个泵头驱动装置,该泵头驱动装置可驱动一个蠕动泵泵头运动或者驱动多个蠕动泵泵头同步运动。在另一些实施例中,蠕动泵可以根据蠕动泵泵头的数量设置为多驱动蠕动泵,即每一个蠕动泵泵头可对应一个泵头驱动装置。在图4所示的示例中,蠕动泵可包括两个泵头驱动装置,两个泵头驱动装置一一对应地分别驱动两个蠕动泵泵头35、36运动。当两个蠕动泵泵头35、36采用一个泵头驱动装置进行驱动时,则简少了泵头驱动装置的数量,简化了蠕动泵的结构,且两个蠕动泵泵头35、36可同步动作,对两个弹性输液软管43、44进行同步挤压。The number of pump head drive devices is not limited. In some examples, the peristaltic pump setting may be a single-drive peristaltic pump, that is, the peristaltic pump may include a pump head driving device that can drive one pump head of the peristaltic pump to move or drive multiple pump heads of the peristaltic pump to move synchronously. In other embodiments, the peristaltic pump can be set as a multi-drive peristaltic pump according to the number of peristaltic pump pump heads, that is, each peristaltic pump pump head can correspond to a pump head drive device. In the example shown in FIG. 4, the peristaltic pump may include two pump head driving devices, and the two pump head driving devices respectively drive the two peristaltic pump pump heads 35 and 36 to move in a one-to-one correspondence. When the two peristaltic pump heads 35, 36 are driven by one pump head drive device, the number of pump head drive devices is reduced, the structure of the peristaltic pump is simplified, and the two peristaltic pump heads 35, 36 can be synchronized Action to simultaneously squeeze the two elastic infusion hoses 43, 44.
在一些示例性实施例中,可采用线性蠕动泵作为溶配药器10的动力驱动。此时,可通过设置一个泵头驱动装置或多个泵头驱动装置驱动多个蠕动泵泵头同步进行线性移动或独立地进行线性移动。In some exemplary embodiments, a linear peristaltic pump may be used as the power drive of the dissolving and dispensing device 10. At this time, one pump head drive device or multiple pump head drive devices can be set to drive multiple peristaltic pump pump heads to move linearly synchronously or independently.
在一些示例性实施例中,两个固定模块,其可安装在主基板5上,并且设置成固定盛药容器,溶配药装置和两个固定模块中的一者位于上方,另一者位于下方。如图1至图4所示的示例中,溶配药装置位于两个固定模块的上方,其中一个固定模块(第二固定模块)可为夹持模块7,设置成固定第二盛药容器,第二盛药容器的类型不限,例如可为输液容器9;另一个固定模块(第一固定模块)可为盛瓶模块6,设置成固定第一盛药容器,第一盛药容器的类型不限,例如可为西林瓶8和/或安瓿瓶54。两个固定模块可安装在主基板5的前侧(即面向操作人员操作的一侧),以便将盛药容器固定 在固定模块上或者从固定模块上取下。In some exemplary embodiments, two fixing modules can be mounted on the main substrate 5 and configured to fix the medicine container, one of the dissolving and dispensing device and the two fixing modules is located above, and the other is located below . In the example shown in Figures 1 to 4, the dissolving and dispensing device is located above two fixed modules, one of the fixed modules (the second fixed module) can be the clamping module 7, which is arranged to fix the second medicine container. The type of the second medicine container is not limited, for example, it may be the infusion container 9; the other fixing module (the first fixing module) may be the bottle holding module 6, which is configured to fix the first medicine container. The type of the first medicine container is not limited. Limit, for example, vial 8 and/or ampoule 54. Two fixing modules can be installed on the front side of the main base plate 5 (that is, the side facing the operator's operation), so that the medicine container can be fixed to or removed from the fixed module.
在一些示例性实施例中,水平运动机构,其可安装在主基板5上并与溶配药装置相连,带动溶配药装置在水平面内运动,进而使两个穿刺器基座41、42上的穿刺器45、46的垂直位置可进行水平位移,使溶配药装置与至少一个固定模块纵向对应。In some exemplary embodiments, the horizontal movement mechanism, which can be installed on the main substrate 5 and connected to the dissolving and dispensing device, drives the dissolving and dispensing device to move in the horizontal plane, thereby causing the puncture on the two puncture bases 41, 42 The vertical positions of the devices 45 and 46 can be displaced horizontally, so that the dissolving and dispensing device corresponds to the at least one fixed module longitudinally.
在一些示例性实施例中,纵向运动机构,其可带动两个固定模块和溶配药装置中的一者纵向移动,使两个穿刺器基座41、42上的穿刺器45、46穿刺盛药容器或与盛药容器分离。在图2和图3所示的示例中,纵向运动机构可包括第一纵向运动机构和第二纵向运动机构,第一纵向运动机构可通过第一承接架12与盛瓶模块(第一固定模块)6连接,并带动盛瓶模块6上下往复移动;第二纵向运动机构可通过第二承接架15与夹持模块(第二固定模块)7连接,并带动夹持模块7上下往复移动,使得盛瓶模块6上的第一盛药容器和夹持模块7上的第二盛药容器分别被溶配药器10的两个穿刺器基座41、42上的穿刺器45、46穿刺,或者,盛瓶模块6上的第一盛药容器和夹持模块7上的第二盛药容器分别与两个穿刺器基座41、42上的穿刺器45、46分离。In some exemplary embodiments, the longitudinal movement mechanism can drive one of the two fixed modules and the dissolving and dispensing device to move longitudinally, so that the piercers 45, 46 on the two piercer bases 41, 42 pierce the medicine. The container may be separated from the medicine container. In the example shown in FIGS. 2 and 3, the longitudinal movement mechanism may include a first longitudinal movement mechanism and a second longitudinal movement mechanism. The first longitudinal movement mechanism may be connected to the bottle holding module (the first fixed module) through the first receiving frame 12 ) 6 is connected, and drives the bottle holding module 6 to move up and down; the second longitudinal movement mechanism can be connected to the clamping module (second fixed module) 7 through the second receiving frame 15, and drives the clamping module 7 to move up and down, so that The first medicine container on the bottle holding module 6 and the second medicine container on the clamping module 7 are respectively pierced by the piercers 45, 46 on the two piercer bases 41, 42 of the dissolving dispenser 10, or, The first medicine container on the bottle holding module 6 and the second medicine container on the clamping module 7 are separated from the piercers 45 and 46 on the two piercer bases 41 and 42 respectively.
在一些示例性实施例中,第一纵向运动机构和第二纵向运动机构可安装在主基板5的后侧,主基板5上可设有第一纵向滑槽,第一承接架12可穿过该第一纵向滑槽,且第一承接架12的前端可与盛瓶模块6连接,后端可与第一纵向运动机构连接;主基板5上可设有第二纵向滑槽,第二承接架15可穿过该第二纵向滑槽,且第二承接架15的前端可与夹持模块7连接,后端可与第二纵向运动机构连接。In some exemplary embodiments, the first longitudinal movement mechanism and the second longitudinal movement mechanism may be installed on the rear side of the main base plate 5, and the main base plate 5 may be provided with a first longitudinal chute through which the first supporting frame 12 can pass. The first longitudinal chute, and the front end of the first receiving frame 12 can be connected with the bottle holding module 6, and the rear end can be connected with the first longitudinal movement mechanism; the main substrate 5 can be provided with a second longitudinal chute, the second receiving frame The frame 15 can pass through the second longitudinal chute, and the front end of the second receiving frame 15 can be connected with the clamping module 7 and the back end can be connected with the second longitudinal movement mechanism.
夹持模块7的结构和工作原理不在本申请中详细描述,可参见申请人提交的名称为“夹持装置和溶配药单元机”、申请号为CN201820517501.0的中国专利申请。The structure and working principle of the clamping module 7 are not described in detail in this application. You can refer to the Chinese patent application filed by the applicant named "Clamping Device and Dispensing Unit Machine" with application number CN201820517501.0.
在一些示例性实施例中,将纵向运动机构设置在主基板5的后侧,两个固定模块设置在主基板5的前侧,一方面,有利于避免纵向运动机构等不易清洁的部件被污染,造成清洁困难;另一方面,盛药容器的安装拆卸操作都是面向操作人员的,使得溶配药单元机的人机界面友好,操作十分方便。In some exemplary embodiments, the longitudinal movement mechanism is arranged on the rear side of the main base plate 5, and two fixed modules are arranged on the front side of the main base plate 5. On the one hand, it is beneficial to prevent the longitudinal movement mechanism and other difficult-to-clean parts from being contaminated. , Causing cleaning difficulties; on the other hand, the installation and disassembly operations of the medicine container are all for the operator, making the man-machine interface of the dissolving and dispensing unit friendly and the operation is very convenient.
在一些示例性实施例中,如图2至图4所示,溶配药装置还可包括副基板30,溶配药器10和蠕动泵均可安装在副基板30上,副基板30可与主基板5活动连接,水平运动机构可带动副基板30运动。当水平运动机构驱动副基板30在水平面内运动时,会带动副基板30上的溶配药器10和蠕动泵等进行运动。In some exemplary embodiments, as shown in FIGS. 2 to 4, the dissolving and dispensing device may further include a sub-substrate 30. Both the dissolving and dispensing device 10 and the peristaltic pump can be mounted on the sub-substrate 30, and the sub-substrate 30 may be combined with the main substrate. 5 Active connection, the horizontal movement mechanism can drive the sub-base plate 30 to move. When the horizontal movement mechanism drives the sub-substrate 30 to move in the horizontal plane, it will drive the dissolving and dispensing device 10 and the peristaltic pump on the sub-substrate 30 to move.
水平运动机构的类型不限。在图2所示的示例中,水平运动机构可为线性移动机构,并带动副基板30直线移动,进而使得水平运动机构驱动溶配药装置进行水平位移,使两个穿刺器基座41、42上的穿刺器45、46的垂直位置与一个或两个固定模块上的盛药容器纵向对应,以便纵向对应的盛药容器被穿刺器45、46穿刺,进而便于溶配药操作。The type of horizontal movement mechanism is not limited. In the example shown in FIG. 2, the horizontal movement mechanism can be a linear movement mechanism, and drives the sub-substrate 30 to move linearly, so that the horizontal movement mechanism drives the dissolving and dispensing device for horizontal displacement, so that the two puncture bases 41, 42 are The vertical position of the piercers 45, 46 corresponds to the longitudinal position of the medicine container on one or two fixed modules, so that the corresponding longitudinally corresponding medicine container is pierced by the piercers 45, 46 to facilitate the dissolving and dispensing operation.
一些示例性实施例中,如图2所示,水平运动机构为线性移动机构,水平运动机构可包括第一横向导轨28、第一横向滑块29和第一横向驱动电机27,第一横向驱动电机27和第一横向导轨28可安装在主基板5上,且第一横向导轨28可与主基板5的板面平行设置,第一横向滑块29可与第一横向导轨28配合,第一横向滑块29可与副基板30连接,第一横向驱动电机27可驱动第一横向滑块29沿第一横向导轨28运动。In some exemplary embodiments, as shown in FIG. 2, the horizontal movement mechanism is a linear movement mechanism. The horizontal movement mechanism may include a first lateral guide rail 28, a first lateral slider 29, and a first lateral drive motor 27. The first lateral drive The motor 27 and the first transverse guide rail 28 can be installed on the main substrate 5, and the first transverse guide rail 28 can be arranged parallel to the surface of the main substrate 5, and the first transverse slider 29 can cooperate with the first transverse guide rail 28. The horizontal sliding block 29 may be connected to the sub-base 30, and the first horizontal driving motor 27 may drive the first horizontal sliding block 29 to move along the first horizontal guide rail 28.
在本实施例中,在进行溶配药时,水平运动机构驱动溶配药装置进行水平位移。首先,水平运动机构的第一横向驱动电机27驱动第一横向滑块29沿第一横向导轨28运动,进而带动副基板30上的溶配药器10横向移动,使得溶配药器10的两个穿刺器基座41、42上的穿刺器45、46的垂直位置与一个或两个固定模块上的两个盛药容器纵向对应。例如:溶配药单元机进行含专用溶媒药物的溶配药时,水平运动机构驱动溶配药器10运动,使溶配药器10的两个穿刺器基座41、42上的穿刺器45、46的垂直位置与盛瓶模块6上放置的两个第一盛药容器纵向对应,以便纵向对应的第一盛药容器被穿刺器45、46穿刺;或者,溶配药单元机进行其他药物的溶配药时,水平运动机构带动副基板30上的溶配药器10移动,使溶配药器10的两个穿刺器基座41、42上的穿刺器45、46的垂直位置分别与盛瓶模块6内固定的第一盛药容器和夹持模块7内固定的第二盛药容器纵向对应,以便纵向对应的第一盛药容器和第二盛药容器分别被穿刺器45、46穿刺。In this embodiment, when dissolving and dispensing the medicine, the horizontal movement mechanism drives the dissolving and dispensing device to move horizontally. First, the first lateral drive motor 27 of the horizontal movement mechanism drives the first lateral slider 29 to move along the first lateral guide rail 28, and then drives the dissolving and dispensing device 10 on the secondary substrate 30 to move laterally, so that the two piercings of the dissolving and dispensing device 10 The vertical positions of the piercers 45 and 46 on the bases 41 and 42 correspond to the two medicine containers on one or two fixed modules longitudinally. For example: when the dissolving and dispensing unit machine is dissolving and dispensing drugs containing special solvents, the horizontal movement mechanism drives the dissolving and dispensing device 10 to move so that the piercing devices 45 and 46 on the two piercing device bases 41 and 42 of the dissolving and dispensing device 10 are vertical. The position corresponds to the two first medicine containers placed on the bottle holding module 6 longitudinally, so that the first medicine container corresponding to the longitudinal direction is pierced by the piercers 45 and 46; or when the dissolving and dispensing unit machine dissolves and disperses other medicines, The horizontal movement mechanism drives the dissolving and dispensing device 10 on the sub-base plate 30 to move, so that the vertical positions of the piercing devices 45 and 46 on the two piercing device bases 41 and 42 of the dissolving and dispensing device 10 are respectively aligned with the first fixed inside the bottle module 6 A medicine container is longitudinally corresponding to the second medicine container fixed in the clamping module 7, so that the first medicine container and the second medicine container corresponding to the longitudinal direction are pierced by the piercers 45 and 46, respectively.
在一些示例性实施例中,水平运动机构可为水平旋转机构,因主基板5与副基板30活动连接,水平旋转机构可带动副基板30水平转动,进而带动溶配药装置水平旋转。在进行溶配药时,水平运动机构可将溶配药器10旋转至恰当位置,使得溶配药器的两个穿刺器基座41、42上的穿刺器45、46的垂直位置分别与盛瓶模块6内固定的两个第一盛药容器纵向对应,或者分别与盛瓶模块6内固定的第一盛药容器和夹持模块7内固定的第二盛药容器对应。In some exemplary embodiments, the horizontal movement mechanism may be a horizontal rotation mechanism. Because the main substrate 5 and the auxiliary substrate 30 are movably connected, the horizontal rotation mechanism can drive the auxiliary substrate 30 to rotate horizontally, thereby driving the dissolving and dispensing device to rotate horizontally. During the dissolving and dispensing, the horizontal movement mechanism can rotate the dissolving and dispensing device 10 to an appropriate position, so that the vertical positions of the piercing devices 45 and 46 on the two piercing device bases 41 and 42 of the dissolving and dispensing device are respectively aligned with the bottle holding module 6 The two internally fixed first medicine containers correspond longitudinally, or respectively correspond to the first medicine container fixed in the bottle container 6 and the second medicine container fixed in the clamping module 7.
在一些示例性实施例中,两个固定模块中的一个固定模块可包括多个固定单元,每一个固定单元设置成设置成固定一个盛药容器。如图1至图2所示的示例中,盛瓶模块6可包括多个固定单元,每个固定单元上可固定一个第一盛药容器,第一盛药容器包括但不限于装有药物的西林瓶8和安瓿瓶54。当盛瓶模块6包括多个固定单元且可固定多个第一盛药容器时,溶配药单元机能实现对多个第一盛药容器进行溶配药操作,进一步提高了溶配药的效率。In some exemplary embodiments, one of the two fixing modules may include a plurality of fixing units, and each fixing unit is configured to fix a medicine container. In the example shown in FIGS. 1 to 2, the bottle holding module 6 may include a plurality of fixing units, and each fixing unit may be fixed with a first medicine container. The first medicine container includes, but is not limited to, a medicine containing Vial 8 and Ampoule 54. When the bottle containing module 6 includes a plurality of fixing units and can fix a plurality of first medicine containers, the dissolving and dispensing unit function can realize the dissolving and dispensing operations on the plurality of first medicine containers, which further improves the efficiency of dissolving and dispensing medicine.
在一些示例性实施例中,如图1至图2所示,盛瓶模块6还可包括固定架55和旋转驱动装置,盛瓶模块6的多个固定单元可固定在固定架55上且呈圆周排列,相应的,多个第一盛药容器可放置在固定单元上且沿圆周排列。盛瓶模块6的固定架55可设计为圆盘状,其上设置有沿圆盘的圆周方向排列的4个固定单元,固定单元可包括夹持释放机构,可固定西林瓶8和/或安瓿瓶54总共4瓶。盛瓶模块6中西林瓶8和/或安瓿瓶54的夹紧固定或释放可通过夹紧释放电机带动夹持释放机构动作实现,其结构和工作方式不在本申请中详细描述,可参见申请人提交的名称为“药瓶夹持装置及其使用方法”、申请号为CN201810603873.X的中国专利申请。采用该专利申请的设计,夹持在盛瓶模块6中的第一盛药容器,在溶配药过程中可以旋转,从而加速药物的溶解。In some exemplary embodiments, as shown in FIGS. 1 to 2, the bottle holding module 6 may further include a fixing frame 55 and a rotation driving device. A plurality of fixing units of the bottle holding module 6 may be fixed on the fixing frame 55 and present Circumferential arrangement, correspondingly, a plurality of first medicine containers can be placed on the fixed unit and arranged along the circumference. The fixing frame 55 of the bottle holding module 6 can be designed in a disc shape, and 4 fixing units arranged along the circumferential direction of the disc are arranged on it. The fixing unit may include a clamping and releasing mechanism to fix the vial 8 and/or ampoule. Bottle 54 totals 4 bottles. The clamping fixation or release of the vial 8 and/or ampoule 54 in the bottle holding module 6 can be realized by the clamping and releasing motor driving the clamping and releasing mechanism. Its structure and working mode are not described in detail in this application, please refer to the applicant The submitted Chinese patent application named "Medicine Bottle Holding Device and Method of Use", application number is CN201810603873.X. With the design of this patent application, the first medicine container clamped in the bottle holding module 6 can be rotated during the dissolution and dispensing process, thereby accelerating the dissolution of the medicine.
在实际运用时,可根据临床使用情况增加或减少夹持释放机构和夹紧释放电机的数量。In actual use, the number of clamp release mechanisms and clamp release motors can be increased or decreased according to clinical use.
在一些示例性实施例中,如图2和图3所示,第一承接架12上可设有第一承接杆40,第一承接杆40上可设有第一卡锁机构32,盛瓶模块6可安装在第一承接杆40上并且可被第一卡锁机构32固定,盛瓶模块6可从第一承 接杆40上取下,方便清洗消毒。In some exemplary embodiments, as shown in FIGS. 2 and 3, the first receiving frame 12 may be provided with a first receiving rod 40, and the first receiving rod 40 may be provided with a first locking mechanism 32, and a bottle The module 6 can be installed on the first receiving rod 40 and can be fixed by the first locking mechanism 32, and the bottle holding module 6 can be removed from the first receiving rod 40 to facilitate cleaning and disinfection.
在一些示例性实施例中,如图1至图3所示,盛瓶模块6还可包括旋转驱动装置,旋转驱动装置可为旋转电机39,或者为气动、液压传动等其他驱动方式,以驱动第一承接杆40转动,带动盛瓶模块6旋转,使盛瓶模块6上的每一个第一盛药容器均能够实现与穿刺器45纵向对应。In some exemplary embodiments, as shown in FIGS. 1 to 3, the bottle holding module 6 may further include a rotary driving device, which may be a rotary motor 39, or other driving methods such as pneumatic or hydraulic transmission to drive The rotation of the first receiving rod 40 drives the rotation of the bottle holding module 6 so that each first medicine holding container on the bottle holding module 6 can be longitudinally corresponding to the piercing device 45.
在进行溶配药时,旋转电机39可直接或通过传动机构间接驱动第一承接杆40转动,第一承接杆40可带动盛瓶模块6转动,使一个第一盛药容器可与穿刺器45纵向对应;然后,第一纵向运动机构(其描述可参见下文)的第一纵向驱动电机23可驱动第一纵向滑块14沿第一纵向导轨13纵向移动,第一纵向滑块14可带动固定在第一承接架12上的第一承接杆40和盛瓶模块6整体纵向移动,以便与穿刺器45纵向对应的第一盛药容器被穿刺器45穿刺;溶配药完成后,第一纵向驱动电机23可驱动第一纵向滑块14沿第一纵向导轨13反向移动,并带动第一承接架12、第一承接杆40和盛瓶模块6整体反向移动,使第一盛药容器与穿刺器45分离。When dissolving and dispensing medicines, the rotating motor 39 can directly or indirectly drive the first receiving rod 40 to rotate through the transmission mechanism. The first receiving rod 40 can drive the bottle holding module 6 to rotate, so that a first medicine holding container can be longitudinally connected to the piercing device 45. Corresponding; then, the first longitudinal drive motor 23 of the first longitudinal movement mechanism (for a description can be found below) can drive the first longitudinal slider 14 to move longitudinally along the first longitudinal guide rail 13, and the first longitudinal slider 14 can be driven and fixed in The first receiving rod 40 on the first receiving frame 12 and the bottle holding module 6 move longitudinally as a whole, so that the first medicine holding container longitudinally corresponding to the piercing device 45 is pierced by the piercing device 45; after the dissolution and dispensing is completed, the first longitudinal drive motor 23 can drive the first longitudinal sliding block 14 to move in the reverse direction along the first longitudinal guide rail 13, and drive the first receiving frame 12, the first receiving rod 40 and the bottle holding module 6 to move in reverse as a whole, so that the first medicine holding container and the puncture The device 45 is separated.
在一些示例性实施例中,如图1所示,盛瓶模块6及旋转驱动装置(即旋转电机39)可采用密封罩2包裹,防止液体溅入,并方便清洁、消毒。In some exemplary embodiments, as shown in FIG. 1, the bottle holding module 6 and the rotating drive device (ie, the rotating motor 39) can be wrapped in a sealed cover 2 to prevent liquid from splashing in and facilitate cleaning and disinfection.
在一些示例性实施例中,盛瓶模块6还可包括震动机构,震动机构设置成可带动盛瓶模块6内的第一盛药容器震动。在第一盛药容器和第二盛药容器中的内容物互相混合时,在第一盛药容器内的内容物为粉剂药物的情况下,震动机构带动第一盛药容器震动可促进粉剂药物的溶解。该震动机构的设置,减少了内容物溶解所需的时间,提高了溶配药的效率。In some exemplary embodiments, the bottle holding module 6 may further include a vibration mechanism, which is configured to drive the first medicine container in the bottle holding module 6 to vibrate. When the contents in the first medicine container and the second medicine container are mixed with each other, when the contents in the first medicine container are powder medicines, the vibration mechanism drives the first medicine container to vibrate to promote the powder medicine The dissolution. The setting of the vibration mechanism reduces the time required for the dissolution of the contents and improves the efficiency of dissolving and dispensing medicines.
多个固定单元固定在固定架55上且呈圆周排列,则可在固定架55上的固定单元上放置多个相应的第一盛药容器,并使第一盛药容器呈圆周排列。此外,通过固定架55,实现了固定架55上的第一盛药容器与旋转电机39的连接。当旋转电机39驱动固定架55旋转运动时,固定架55上的第一盛药容器在旋转电机39的驱动下,也作相应的旋转运动,以调节放置在固定架55上的第一盛药容器的位置,使得穿刺器可逐个穿刺第一盛药容器,从而提高配药效率。If a plurality of fixing units are fixed on the fixing frame 55 and arranged in a circle, a plurality of corresponding first medicine containers can be placed on the fixing unit on the fixing frame 55, and the first medicine containers are arranged in a circle. In addition, through the fixing frame 55, the connection between the first medicine container on the fixing frame 55 and the rotating motor 39 is realized. When the rotating motor 39 drives the fixing frame 55 to rotate, the first medicine container on the fixing frame 55 is driven by the rotating motor 39 to make a corresponding rotation movement to adjust the first medicine container placed on the fixing frame 55 The position of the container allows the piercer to pierce the first medicine container one by one, thereby improving the efficiency of dispensing.
在一些示例性实施例中,如图5所示,盛瓶模块49可包括固定架56和 线性驱动装置,固定架56可安装在第一承接架12上并可相对第一承接架12沿垂直于主基板5的板面的方向位移,多个固定单元可固定在固定架56上且呈线性排列;相应地,多个第一盛药容器可固定在固定单元上且呈线性排列。In some exemplary embodiments, as shown in FIG. 5, the bottle holding module 49 may include a fixing frame 56 and a linear drive device. The fixing frame 56 may be installed on the first supporting frame 12 and may be perpendicular to the first supporting frame 12. With displacement in the direction of the board surface of the main substrate 5, a plurality of fixing units can be fixed on the fixing frame 56 and arranged linearly; correspondingly, a plurality of first medicine containers can be fixed on the fixing unit and arranged linearly.
在本实施例中,如图5所示,盛瓶模块49可设计为线性,其盛瓶模块49的固定架56上可设有线性排列的四个固定单元,固定单元可包括夹持释放机构,可固定西林瓶8和/或安瓿瓶54总共4瓶。盛瓶模块49中西林瓶8和/或安瓿瓶54的夹紧固定或释放可通过夹紧释放电机带动夹持释放机构动作实现,其结构和工作原理不在本申请中详细描述,可参见申请人提交的名称为“药瓶夹持装置及其使用方法”、申请号为CN201810603873.X的中国专利申请。采用该专利申请的设计,夹持在盛瓶模块49中的第一盛药容器,在溶配药过程中可以旋转,从而加速药物的溶解。在实际运用时,可根据临床使用情况增加或减少夹持释放机构的数量。In this embodiment, as shown in FIG. 5, the bottle holding module 49 can be designed to be linear, and the fixing frame 56 of the bottle holding module 49 can be provided with four fixing units arranged linearly, and the fixing unit can include a clamping release mechanism. , Can fix a total of 4 bottles of vials 8 and/or ampoules 54. The clamping fixation or release of the vial 8 and/or ampoule 54 in the bottle holding module 49 can be realized by the clamping and releasing motor driving the clamping and releasing mechanism. The structure and working principle are not described in detail in this application, please refer to the applicant The submitted Chinese patent application named "Medicine Bottle Holding Device and Method of Use", application number is CN201810603873.X. With the design of this patent application, the first medicine container clamped in the bottle holding module 49 can be rotated during the dissolution and dispensing process, thereby accelerating the dissolution of the medicine. In actual use, the number of clamping and releasing mechanisms can be increased or decreased according to clinical use.
在一些示例性实施例中,如图5所示,盛瓶模块49的线性驱动装置可包括相配合的第二横向导轨52、第二横向滑块53和第二横向驱动电机50,其中,第二横向滑块53和第二横向驱动电机50可固定在第一承接架12上,第二横向导轨52可固定在固定架56上,第二横向驱动电机50驱动固定在固定架56上的传动机构51横向位移或直接驱动第二横向滑块52位移,使第二横向滑块53可沿第二横向导轨52相对移动,进而使盛瓶模块49上的每一个第一盛药容器均能够实现与溶配药器10的穿刺器45纵向对应。In some exemplary embodiments, as shown in FIG. 5, the linear driving device of the bottle holding module 49 may include a second transverse rail 52, a second transverse sliding block 53, and a second transverse driving motor 50 that are matched with each other. The two transverse slide blocks 53 and the second transverse drive motor 50 can be fixed on the first supporting frame 12, the second transverse guide rail 52 can be fixed on the fixing frame 56, and the second lateral drive motor 50 drives the transmission fixed on the fixing frame 56 The mechanism 51 laterally shifts or directly drives the second lateral sliding block 52 to displace, so that the second lateral sliding block 53 can move relative to each other along the second lateral guide rail 52, so that each first medicine container on the bottle holding module 49 can be realized The piercer 45 of the dissolving and dispensing device 10 corresponds longitudinally.
在进行溶配药时,第二横向驱动电机50可驱动固定在固定架56上的传动机构51横向位移,使第二横向滑块53可沿第二横向导轨52相对移动,使一个第一盛药容器与穿刺器45纵向对应;然后,第一纵向驱动机构带动盛瓶模块49整体纵向移动,以便与穿刺器45纵向对应的第一盛药容器被穿刺器45穿刺。溶配药完成后,第一纵向驱动带动盛瓶模块49整体反向移动,使第一盛药容器与穿刺器45分离。When dissolving medicines, the second transverse drive motor 50 can drive the transmission mechanism 51 fixed on the fixing frame 56 to move laterally, so that the second transverse sliding block 53 can move relatively along the second transverse guide rail 52 to make a first medicine holder The container is longitudinally corresponding to the piercer 45; then, the first longitudinal drive mechanism drives the entire bottle holding module 49 to move longitudinally, so that the first medicinal container corresponding to the piercer 45 longitudinally is pierced by the piercer 45. After the dissolving and dispensing of the medicine is completed, the first longitudinal drive drives the bottle-containing module 49 to move in reverse as a whole, so that the first medicine-containing container is separated from the piercing device 45.
通过固定架56,实现固定架56上的第一盛药容器与线性驱动装置的连接,线性驱动装置可驱动固定架56线性移动。在进行溶配药时,可首先利用线性驱动装置将固定架56上的第一盛药容器调节至恰当位置,以便穿刺 器45逐个穿刺第一盛药容器,这样可方便进行溶配药操作,进而提高配药效率。Through the fixing frame 56, the connection between the first medicine container on the fixing frame 56 and the linear driving device is realized, and the linear driving device can drive the fixing frame 56 to move linearly. When dissolving and dispensing medicine, the linear driving device can be used to adjust the first medicine container on the fixing frame 56 to a proper position, so that the puncture device 45 pierces the first medicine container one by one, which facilitates the dissolution and dispensing operation, thereby improving Dispensing efficiency.
盛瓶模块49的固定架56可根据需要,设计成沿平行于主基板5的板面的方向移动,或与主基板5的板面呈任意角度。The fixing frame 56 of the bottle holding module 49 can be designed to move in a direction parallel to the surface of the main substrate 5 or at any angle to the surface of the main substrate 5 as required.
在一些示例性实施例中,如图5所示,线性驱动装置的第二横向驱动电机50可包括旋转电机和能够将旋转运动转换成直线移动的传动机构51(如齿轮齿轮传动机构等),或者可包括线性电机。线性电机可将电能直接转换成直线运动机械能,而不需要任何中间的运动转换机构,因此,线性电机可直接驱动第二横向滑块53进行移动,且线性电机的结构简单,溶配药单元机的整体重量减轻。In some exemplary embodiments, as shown in FIG. 5, the second lateral drive motor 50 of the linear drive device may include a rotating motor and a transmission mechanism 51 (such as a gear-gear transmission mechanism, etc.) capable of converting rotary motion into linear movement, Or a linear motor can be included. The linear motor can directly convert electrical energy into linear motion mechanical energy without any intermediate motion conversion mechanism. Therefore, the linear motor can directly drive the second horizontal slider 53 to move, and the linear motor has a simple structure and is suitable for dissolving and dispensing unit machines. Overall weight reduction.
线性驱动装置可使用其他动力结构例如气动、液压传动的动力结构,来输出直线或旋转运动。The linear drive device can use other power structures such as pneumatic and hydraulic power structures to output linear or rotary motion.
在一些示例性实施例中,如附图2所示,第一纵向运动机构可包括第一纵向导轨13、第一纵向滑块14和第一纵向驱动电机23;其中,第一纵向滑块14可安装在第一承接架12上,第一纵向导轨13固定在主基板5上,第一纵向驱动电机23设置成可驱动第一纵向滑块14沿第一纵向导轨13移动。In some exemplary embodiments, as shown in FIG. 2, the first longitudinal movement mechanism may include a first longitudinal guide rail 13, a first longitudinal slider 14 and a first longitudinal drive motor 23; wherein, the first longitudinal slider 14 It can be installed on the first supporting frame 12, the first longitudinal guide rail 13 is fixed on the main substrate 5, and the first longitudinal drive motor 23 is configured to drive the first longitudinal slider 14 to move along the first longitudinal guide rail 13.
当盛瓶模块6位于溶配药器10的下方时,第一纵向驱动电机23可驱动第一纵向滑块14沿第一纵向导轨13向上移动,第一纵向滑块14可通过与第一纵向滑块14相连的第一承接架12带动盛瓶模块6和第一盛药容器向上运动,使第一盛药容器被穿刺器45穿刺,以便进行溶配药操作;当溶配药完成后,第一纵向驱动电机23可驱动第一纵向滑块14沿第一纵向导轨13向下移动,第一纵向滑块14可通过第一承接架12带动盛瓶模块6和第一盛药容器向下运动,使第一盛药容器与穿刺器45分离。When the bottle holding module 6 is located below the dissolving and dispensing device 10, the first longitudinal drive motor 23 can drive the first longitudinal slider 14 to move upward along the first longitudinal guide rail 13, and the first longitudinal slider 14 can pass and the first longitudinal slide The first receiving frame 12 connected to the block 14 drives the bottle holding module 6 and the first medicine container to move upward, so that the first medicine container is pierced by the piercing device 45 for the dissolution and dispensing operation; when the dissolution and dispensing is completed, the first longitudinal direction The driving motor 23 can drive the first longitudinal slider 14 to move downward along the first longitudinal guide rail 13, and the first longitudinal slider 14 can drive the bottle holding module 6 and the first medicine container to move downward through the first receiving frame 12, so that The first medicine container is separated from the piercing device 45.
在一些示例性实施例中,如图2所示,第二纵向运动机构可包括第二纵向导轨16、第二纵向滑块17和第二纵向驱动电机24;其中,第二纵向滑块17可固定在第二承接架15上,第二纵向导轨16可固定在主基板5上,第二纵向驱动电机24设置成可驱动第二纵向滑块17沿第二纵向导轨16移动。In some exemplary embodiments, as shown in FIG. 2, the second longitudinal motion mechanism may include a second longitudinal guide rail 16, a second longitudinal slider 17, and a second longitudinal drive motor 24; wherein, the second longitudinal slider 17 may Fixed on the second supporting frame 15, the second longitudinal guide rail 16 can be fixed on the main substrate 5, and the second longitudinal drive motor 24 is arranged to drive the second longitudinal slider 17 to move along the second longitudinal guide rail 16.
夹持模块7位于溶配药器10的下方时,第二纵向驱动电机24可驱动第 二纵向滑块17沿第二纵向导轨16向上移动,第二纵向滑块17可通过与其相连的第二承接架15带动夹持模块7和固定在其中的第二盛药容器向上运动,使固定在夹持模块7上的第二盛药容器被穿刺器46穿刺,以便进行溶配药操作;当溶配药完成后,第二纵向驱动电机24可驱动第二纵向滑块17沿第二纵向导轨16向下移动,第二纵向滑块17可通过第二承接架15带动夹持模块7和第二盛药容器向下运动,使第二盛药容器与穿刺器46分离。When the clamping module 7 is located below the dissolving and dispensing device 10, the second longitudinal drive motor 24 can drive the second longitudinal slider 17 to move upward along the second longitudinal guide rail 16, and the second longitudinal slider 17 can pass through the second bearing connected to it. The frame 15 drives the clamping module 7 and the second medicine container fixed therein to move upward, so that the second medicine container fixed on the clamping module 7 is pierced by the piercing device 46 for the dissolving and dispensing operation; when the dissolving and dispensing is completed After that, the second longitudinal drive motor 24 can drive the second longitudinal slider 17 to move downward along the second longitudinal guide rail 16, and the second longitudinal slider 17 can drive the clamping module 7 and the second medicine container through the second receiving frame 15 Move downward to separate the second medicine container from the piercer 46.
在一些示例性实施例中,如图1和图2所示,纵向运动机构可位于主基板5的后侧,主基板5的后侧可固定有第一机罩3,第一机罩3可将纵向运动机构罩住,一方面有利于避免其部件暴露在外,防止药液或灰尘污染;另一方面,当需要维修纵向运动机构时可将第一机罩3拆下,使纵向运动机构的结构露出,然后方便地进行维修。In some exemplary embodiments, as shown in FIGS. 1 and 2, the longitudinal movement mechanism may be located on the rear side of the main base plate 5, the rear side of the main base plate 5 may be fixed with the first hood 3, and the first hood 3 may be Covering the longitudinal movement mechanism, on the one hand, is beneficial to prevent its parts from being exposed and prevent chemical liquid or dust pollution; on the other hand, when the longitudinal movement mechanism needs to be repaired, the first hood 3 can be removed to make the longitudinal movement mechanism effective The structure is exposed and then easy to repair.
在一些示例性实施例中,溶配药装置可位于两个固定模块的上方,即溶配药器10可在上方,固定模块可在下方。在图1至图4所示的示例中,溶配药器10在上方,夹持模块7和盛瓶模块6在下方,因此第二盛药容器(例如输液容器9)以及第一盛药容器(例如西林瓶8、安瓿瓶54等)可以正立地安装在夹持模块7和盛瓶模块6上,一方面使得输液容器9以及西林瓶8、安瓿瓶54的安装方便,另一方面可避免输液容器9以及西林瓶8、安瓿瓶54倒置时内容物泄露的问题。In some exemplary embodiments, the dissolving and dispensing device may be located above the two fixed modules, that is, the dissolving and dispensing device 10 may be above and the fixed module may be below. In the example shown in Figures 1 to 4, the dissolving and dispensing device 10 is above, the clamping module 7 and the bottle holding module 6 are below, so the second medicine container (for example, the infusion container 9) and the first medicine container ( For example, vials 8, ampoules 54, etc.) can be installed upright on the clamping module 7 and the bottle holding module 6, which on the one hand makes the installation of the infusion container 9 and the vials 8, and ampoules 54 easy, and on the other hand can avoid infusion The problem that the contents of the container 9, the vial 8, and the ampoule 54 are inverted when they leak.
在一些示例性实施例中,如图1和图2所示,水平运动机构可位于主基板5的后侧,且当溶配药装置位于两个固定模块的上方时,驱动溶配药装置水平移动的水平运动机构可位于驱动固定模块纵向移动的纵向运动机构的上方,这样设置有利于简化溶配药单元机的结构,使溶配药单元机的设置合理。In some exemplary embodiments, as shown in FIGS. 1 and 2, the horizontal movement mechanism may be located on the rear side of the main base plate 5, and when the dissolving and dispensing device is located above the two fixed modules, the horizontal movement of the dissolving and dispensing device is driven. The horizontal movement mechanism can be located above the longitudinal movement mechanism that drives the fixed module to move longitudinally. This arrangement is beneficial to simplify the structure of the dissolving and dispensing unit machine, and make the setting of the dissolving and dispensing unit machine reasonable.
如图1和图2所示,水平运动机构位于主基板5的后侧,第一机罩3可将水平运动机构罩住以避免其部件暴露在外,防止药液或灰尘污染。第一机罩3的上部可设有安装槽,副基板30可穿过第一机罩3的安装槽后与水平运动机构连接,而水平运动机构可安装在主基板5上,使得主基板5与副基板30连接在一起。As shown in Figs. 1 and 2, the horizontal movement mechanism is located on the rear side of the main substrate 5. The first hood 3 can cover the horizontal movement mechanism to prevent its parts from being exposed and prevent chemical liquid or dust pollution. The upper part of the first hood 3 may be provided with a mounting groove, the sub-base 30 may pass through the mounting groove of the first hood 3 and then be connected to the horizontal movement mechanism, and the horizontal movement mechanism may be installed on the main base 5 so that the main base 5 Connect with the sub-substrate 30.
在一些示例性实施例中,如图1所示,副基板30上可固定有第二机罩4, 第二机罩4可将溶配药装置的部件罩住,一方面,有利于避免溶配药装置的部件暴露在外,防止液体溅入污染内部的部件;另一方面,当需要维修溶配药装置时,可将第二机罩4拆下,使溶配药装置露出,然后方便地进行维修。In some exemplary embodiments, as shown in FIG. 1, a second hood 4 may be fixed on the secondary substrate 30, and the second hood 4 may cover the components of the dissolving and dispensing device. On the one hand, it is beneficial to avoid dissolving and dispensing. The components of the device are exposed to prevent liquid from splashing into the internal components; on the other hand, when the dissolving and dispensing device needs to be repaired, the second hood 4 can be removed to expose the dissolving and dispensing device, and then maintenance can be conveniently performed.
在一些示例性实施例中,溶配药装置还可包括安装在副基板30上的溶配药器固定控制机构。在图3和图4所示的示例中,溶配药器固定控制机构可包括第三纵向运动机构、固定夹块37、38和运动夹块11,溶配药器10可安装在运动夹块11上,第三纵向运动机构能够带动运动夹块11上下往复运动,带动溶配药器10上下往复运动,使得溶配药器10可被固定夹块37、38、运动夹块11共同夹持固定,此时,穿刺器45、46的位置固定,弹性输液软管43、44可被蠕动泵泵头35、36挤压。In some exemplary embodiments, the dissolving and dispensing device may further include a dissolving and dispensing device fixing control mechanism installed on the sub-base 30. In the example shown in Figures 3 and 4, the dissolving and dispensing device fixed control mechanism may include a third longitudinal movement mechanism, fixed clamp blocks 37, 38, and a moving clamp block 11. The dissolving and dispensing device 10 may be mounted on the moving clamp block 11. , The third longitudinal movement mechanism can drive the moving clamp block 11 to reciprocate up and down, and drive the dissolving dispenser 10 to reciprocate up and down, so that the dissolving dispenser 10 can be clamped and fixed by the fixed clamp blocks 37, 38 and the moving clamp block 11. , The position of the puncture device 45, 46 is fixed, and the elastic infusion hose 43, 44 can be squeezed by the pump head 35, 36 of the peristaltic pump.
在一些示例性实施例中,第三纵向运动机构可位于副基板30的后侧,溶配药器10及运动夹块11可位于副基板30的前侧,第三纵向运动机构可通过第三承接架18与固定溶配药器10的运动夹块11连接,且副基板30上可设有第三纵向滑槽,第三承接架18可穿过该第三纵向滑槽,第三承接架18的前端可与运动夹块11连接,后端可与第三纵向运动机构连接。In some exemplary embodiments, the third longitudinal movement mechanism may be located on the rear side of the secondary base plate 30, the dissolving and dispensing device 10 and the movement clamp 11 may be located on the front side of the secondary base plate 30, and the third longitudinal movement mechanism may be provided by the third receiving plate. The frame 18 is connected to the movable clamp 11 of the fixed dissolving and dispensing device 10, and a third longitudinal chute can be provided on the secondary base plate 30, and the third supporting frame 18 can pass through the third longitudinal chute. The front end can be connected with the movement clamping block 11, and the rear end can be connected with the third longitudinal movement mechanism.
在一些示例性实施例中,如图2和图4所示,第三纵向运动机构可包括第三纵向导轨19、20、第三纵向滑块21、22和第三纵向驱动电机25、26。其中,第三纵向滑块21、22可固定在第三承接架18上并位于第三承接架18的两端,第三纵向导轨19、20可固定在副基板30上,第三纵向驱动电机25、26设置成可分别驱动第三纵向滑块21、22沿第三纵向导轨19、20移动。In some exemplary embodiments, as shown in FIGS. 2 and 4, the third longitudinal movement mechanism may include third longitudinal guide rails 19, 20, third longitudinal sliders 21, 22 and third longitudinal drive motors 25, 26. Among them, the third longitudinal sliders 21, 22 can be fixed on the third supporting frame 18 and located at both ends of the third supporting frame 18, the third longitudinal guide rails 19, 20 can be fixed on the auxiliary base plate 30, and the third longitudinal drive motor 25 and 26 are arranged to drive the third longitudinal sliders 21 and 22 to move along the third longitudinal guide rails 19 and 20 respectively.
在一些示例性实施例中,溶配药器固定控制机构的运动夹块11可位于蠕动泵泵头35、36的下侧;溶配药器固定控制机构的固定夹块37、38可分别列于蠕动泵泵头35、36的两侧,呈相对应关系。固定夹块37、38、运动夹块11的结构配合溶配药器10和蠕动泵泵头35、36的结构,当溶配药器10安装在运动夹块11上时,第三纵向驱动电机25、26可分别驱动第三纵向滑块21、22沿第三纵向导轨19、20向上移动,第三纵向滑块21、22可通过与其相连的第三承接架18带动运动夹块11朝向固定夹块37、38运动,当溶配药器10触碰固定夹块37、38时,溶配药器10可被固定夹块37、38、运动夹块11共同夹持固定,使穿刺器45、46的位置固定,蠕动泵泵头35、 36与弹性输液软管43、44可成挤压和待驱动状态。In some exemplary embodiments, the moving clamp 11 of the fixing control mechanism of the dissolving and dispensing device may be located on the underside of the pump heads 35 and 36 of the peristaltic pump; the fixing clamping blocks 37 and 38 of the fixing and controlling mechanism of the dissolving and dispensing device may be arranged in the peristaltic respectively. The two sides of the pump heads 35 and 36 correspond to each other. The structure of the fixed clamp blocks 37, 38 and the moving clamp block 11 matches the structure of the dissolving and dispensing device 10 and the peristaltic pump heads 35, 36. When the dissolving and dispensing device 10 is installed on the moving clamp block 11, the third longitudinal drive motor 25, 26 can respectively drive the third longitudinal sliders 21, 22 to move upward along the third longitudinal guide rails 19, 20, and the third longitudinal sliders 21, 22 can drive the moving clamp block 11 toward the fixed clamp block through the third supporting frame 18 connected to it. 37 and 38 move. When the dissolving and dispensing device 10 touches the fixed clamping blocks 37 and 38, the dissolving and dispensing device 10 can be clamped and fixed by the fixed clamping blocks 37, 38 and the movable clamping block 11, so that the position of the piercing device 45, 46 Fixed, the peristaltic pump heads 35, 36 and the elastic infusion hoses 43, 44 can be squeezed and ready to be driven.
下面结合五个示例,说明采用本申请实施例中的溶配药单元机进行溶配药的过程。In the following, five examples are combined to illustrate the process of dissolving and distributing medicine using the dissolving and dispensing unit machine in the embodiment of the present application.
示例一:配制安瓿瓶装药物Example 1: Preparation of drugs in ampoules
采用图1至图4中所示的溶配药单元机进行配制的过程为:The process of using the dissolving and dispensing unit machine shown in Figures 1 to 4 for preparation is:
首先,可将溶配药器10安装在溶配药器固定控制机构的运动夹块11上;然后,第三纵向驱动装置可驱动运动夹块11向固定夹块37、38运动,至溶配药器10与固定夹块37、38接触,使溶配药器10被固定夹块37、38、运动夹块11共同夹持固定,穿刺器45、46的位置固定,这时蠕动泵泵头35、36与弹性输液软管43、44成挤压和待驱动状态。First, the dissolving and dispensing device 10 can be installed on the moving clamp 11 of the fixing and controlling mechanism of the dissolving and dispensing device; then, the third longitudinal drive device can drive the moving clamp 11 to move to the fixed clamping blocks 37, 38 to the dissolving and dispensing device 10. In contact with the fixed clamp blocks 37 and 38, the dissolving and dispensing device 10 is clamped and fixed by the fixed clamp blocks 37, 38 and the moving clamp block 11. The positions of the punctures 45 and 46 are fixed. At this time, the pump heads 35, 36 of the peristaltic pump and The elastic infusion hoses 43 and 44 are squeezed and to be driven.
将输液容器9定位固定至夹持模块7内。Position the infusion container 9 into the clamping module 7.
将安瓿瓶54放置于盛瓶模块6内,这时安瓿瓶54的开口向上,驱动盛瓶模块6的夹紧释放电机,将放置在盛瓶模块6内的安瓿瓶54夹紧定位。The ampoule 54 is placed in the bottle holding module 6, and the opening of the ampoule 54 is upward, driving the clamping release motor of the bottle holding module 6 to clamp and position the ampoule 54 placed in the bottle holding module 6.
其中,溶配药器10、输液容器9和安瓿瓶54的放置安装次序可以互换。Among them, the placement and installation sequence of the dissolving and dispensing device 10, the infusion container 9 and the ampoule 54 can be interchanged.
然后,水平运动机构可驱动溶配药装置水平位移,使溶配药器10两端的穿刺器45、46的垂直轴心分别与盛瓶模块6上处于待配位的安瓿瓶54的轴心和输液容器9的插入口的轴心处于同一轴线上。Then, the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the ampoule 54 to be coordinated and the infusion container on the bottle module 6 The axis of the insertion port of 9 is on the same axis.
其次,第一纵向驱动电机23可驱动第一承接架12纵向向上移动,并带动盛瓶模块6纵向向上移动,使溶配药器10的穿刺器45可插入待配位的安瓿瓶54内,并且使穿刺器45尽可能地插入安瓿瓶54的瓶底处;随后或并行地,第二纵向驱动电机24可带动第二承接架15纵向向上移动,进而带动输液容器9纵向移动,使溶配药器10的穿刺器46刺穿输液容器9的胶塞内。Secondly, the first longitudinal drive motor 23 can drive the first receiving frame 12 to move longitudinally upwards, and drive the bottle holding module 6 to move longitudinally upwards, so that the piercer 45 of the dissolving and dispensing device 10 can be inserted into the ampoule 54 to be coordinated, and The puncture device 45 is inserted into the bottom of the ampoule 54 as much as possible; subsequently or in parallel, the second longitudinal drive motor 24 can drive the second receiving frame 15 to move longitudinally upward, and then drive the infusion container 9 to move longitudinally, so that the dissolving and dispensing device The piercer 46 of 10 pierces the rubber stopper of the infusion container 9.
随后,蠕动泵工作,按照医嘱定量将安瓿瓶54内的药液泵入输液容器9中或将安瓿瓶54内的全部药液泵入输液容器9中;Subsequently, the peristaltic pump works to pump the liquid medicine in the ampoule 54 into the infusion container 9 or pump all the medicine liquid in the ampoule 54 into the infusion container 9 according to the doctor's order;
(i)若盛瓶模块6上仅放置一个安瓿瓶54时,则此时溶配药过程完成,用第一纵向驱动电机23带动第一承接架12反向纵向位移(向下位移),用第二纵向驱动电机24带动第二承接架15反向纵向位移(向下位移),使溶配药器10的穿刺器45、46分别与安瓿瓶54和输液容器9分离,即完成配制 操作;(i) If only one ampoule 54 is placed on the bottle holding module 6, then the dissolving and dispensing process is completed. The first longitudinal drive motor 23 is used to drive the first receiving frame 12 to reverse longitudinal displacement (downward displacement). The two longitudinal drive motors 24 drive the second receiving frame 15 to reverse longitudinal displacement (downward displacement), so that the piercers 45 and 46 of the dissolving and dispensing device 10 are separated from the ampoule 54 and the infusion container 9 respectively, and the preparation operation is completed;
(ii)若盛瓶模块上放置多个安瓿瓶,(ii) If multiple ampoules are placed on the bottle holding module,
在第一纵向驱动电机23带动安瓿瓶54向下位移,使穿刺器45与安瓿瓶54分离后,旋转电机39可带动第一承接杆40和盛瓶模块6转动,使盛瓶模块6上的下一安瓿瓶54转动至待配位,再用第一纵向驱动电机23带动第一承接架12纵向向上移动,使穿刺器45插入该下一安瓿瓶54,并且使穿刺器45尽可能地插入该下一安瓿瓶54的瓶底处。随后,再按照上述配药程序,启动蠕动泵,按照医嘱,将该下一安瓿瓶54内所需的药物泵入输液容器9中。After the first longitudinal drive motor 23 drives the ampoule 54 to move downwards to separate the piercer 45 from the ampoule 54, the rotating motor 39 can drive the first receiving rod 40 and the bottle holding module 6 to rotate, so that the The next ampoule 54 is rotated to the position to be coordinated, and then the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to move vertically upwards, so that the piercer 45 is inserted into the next ampoule 54 and the piercer 45 is inserted as far as possible The bottom of the next ampoule 54. Subsequently, according to the above-mentioned dispensing procedure, the peristaltic pump is started, and the medicine required in the next ampoule 54 is pumped into the infusion container 9 according to the doctor's order.
重复上述步骤(ii),按照医嘱,直至所有的安瓿瓶54内所需的药物泵入输液容器9中,此时溶配药过程完成。Repeat the above step (ii) and follow the doctor's order until all the required medicines in the ampoules 54 are pumped into the infusion container 9, at which time the dissolving and dispensing process is completed.
溶配药过程完成后,用第一纵向驱动电机23带动第一承接架12向下位移,用第二纵向驱动电机24带动第二承接架15向下位移,使溶配药器药的穿刺器45、46分别与安瓿瓶54和输液容器9分离,即完成配制操作。After the dissolving and dispensing process is completed, the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to move downward, and the second longitudinal drive motor 24 is used to drive the second receiving frame 15 to move downward, so that the piercing device 45, 46 is separated from the ampoule 54 and the infusion container 9 respectively, and the preparation operation is completed.
采用图5所示的溶配药单元机进行该配置操作时,与采用图1至图4的溶配药单元机进行配制的不同之处在于:盛瓶模块49上放置多个安瓿瓶54时的步骤(ii)。When the dissolving and dispensing unit machine shown in Fig. 5 is used for this configuration operation, the difference from the dissolving and dispensing unit machine shown in Figs. 1 to 4 is that the steps when multiple ampoules 54 are placed on the bottle holding module 49 (ii).
采用图5所示的溶配药单元机进行该配置操作时的步骤(ii)为:Step (ii) when the dissolving and dispensing unit machine shown in Figure 5 is used for this configuration operation is:
如盛瓶模块49放置两个安瓿瓶54时,第一纵向驱动电机带动盛瓶模块49向下位移,使穿刺器45与安瓿瓶54分离;然后,第二横向驱动电机50驱动盛瓶模块49横向移动,使盛瓶模块49横向移动至下一安瓿瓶54与穿刺器纵向相对应的位置;再用第一纵向驱动电机带动第一承接架纵向向上移动,使穿刺器45插入该下一安瓿瓶54内,并且使穿刺器45尽可能地插入安瓿瓶54的瓶底处;随后,再按照上述配药程序,启动蠕动泵,按照医嘱将安瓿瓶54内所需的药物泵入输液容器9中,此时溶配药过程完成;For example, when two ampoules 54 are placed in the bottle holding module 49, the first longitudinal drive motor drives the bottle holding module 49 to move downward to separate the piercer 45 from the ampoule 54; then, the second horizontal drive motor 50 drives the bottle holding module 49 Move laterally to make the bottle holding module 49 move laterally to the position of the next ampoule 54 corresponding to the longitudinal direction of the puncture; and then use the first longitudinal drive motor to drive the first receiving frame to move vertically upward, so that the puncture 45 is inserted into the next ampoule. Insert the puncture device 45 into the bottom of the ampoule 54 as far as possible; then, according to the above-mentioned dispensing procedure, start the peristaltic pump, and pump the required medicine in the ampoule 54 into the infusion container 9 according to the doctor’s instructions , The dissolution and dispensing process is now complete;
若盛瓶模块49放置三个以上的安瓿瓶54时,则重复上述步骤(ii),按照医嘱直至将有的安瓿瓶54内所需的药物泵入输液容器9中,此时溶配药过程完成。If more than three ampoules 54 are placed in the bottle holding module 49, repeat the above step (ii) and follow the doctor's instructions until the required medicine in some ampoules 54 is pumped into the infusion container 9, and the dissolving and dispensing process is completed. .
示例二:配制西林瓶装固体药物Example 2: Preparation of solid drugs in vials
采用图1至图4所示的溶配药单元机进行配制的过程为:The process of using the dissolving and dispensing unit machine shown in Figure 1 to Figure 4 for preparation is:
首先,可将溶配药器10安装在溶配药器固定控制机构的运动夹块11上;然后,第三纵向驱动电机25、26可驱动运动夹块11向固定夹块37、38运动,至溶配药器10与固定夹块37、38接触,使溶配药器10被固定夹块37、38、运动夹块11共同夹持固定,穿刺器45、46的位置固定,这时蠕动泵泵头35、36与弹性输液软管43、44成挤压和待驱动状态。First, the dissolving dispenser 10 can be installed on the moving clamp 11 of the fixing control mechanism of the dissolving dispenser; then, the third longitudinal drive motor 25, 26 can drive the moving clamp 11 to move to the fixed clamps 37, 38 until the dissolving The dispenser 10 is in contact with the fixed clamp blocks 37, 38, so that the dissolving dispenser 10 is clamped and fixed by the fixed clamp blocks 37, 38 and the moving clamp block 11. The positions of the piercers 45, 46 are fixed, and then the peristaltic pump head 35 , 36 and the elastic infusion hose 43, 44 are squeezed and ready to be driven.
将输液容器9定位固定至夹持模块7内。Position the infusion container 9 into the clamping module 7.
将西林瓶8放置于盛瓶模块6内,这时西林瓶8的胶塞向上,驱动盛瓶模块6的夹紧释放电机,将放置在盛瓶模块6内的西林瓶8夹紧并定位。Place the vial 8 in the bottle holding module 6, and at this time, the rubber stopper of the vial 8 is upward, driving the clamping release motor of the bottle holding module 6 to clamp and position the vial 8 placed in the bottle holding module 6.
其中,溶配药器10、输液容器9和西林瓶8的放置安装次序可以互换。Among them, the placing and installation sequence of the dissolving and dispensing device 10, the infusion container 9 and the vial 8 can be interchanged.
然后,水平运动机构可驱动溶配药装置水平位移,使溶配药器10两端的穿刺器45、46的垂直轴心分别与盛瓶模块6上西林瓶8的轴心和输液容器9的插入口的轴心处于同一轴线上。Then, the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the vial 8 on the bottle module 6 and the insertion port of the infusion container 9 The shaft centers are on the same axis.
其次,第一纵向驱动电机23可带动第一承接架12纵向向上移动,并带动盛瓶模块6纵向向上位移,使溶配药器10的穿刺器45可插入西林瓶8内,并且使穿刺器45尽可能地插入西林瓶8的瓶底处,也可设置为穿刺器45刚刺穿西林瓶8的胶塞;随后或同时,第二纵向驱动电机24可带动第二承接架15纵向向上位移,进而带动输液容器9纵向向上移动,使溶配药器10的穿刺器46刺穿输液容器9的胶塞内。Secondly, the first longitudinal drive motor 23 can drive the first receiving frame 12 to move vertically upwards, and drive the bottle holding module 6 to move upwards longitudinally, so that the piercer 45 of the dissolving and dispensing device 10 can be inserted into the vial 8 and the piercing device 45 Insert into the bottom of the vial 8 as much as possible, or it can be set as the piercing device 45 to just pierce the rubber stopper of the vial 8; subsequently or at the same time, the second longitudinal drive motor 24 can drive the second receiving frame 15 to move vertically upward, In turn, the infusion container 9 is driven to move longitudinally upward, so that the piercer 46 of the dissolving and dispensing device 10 pierces the rubber plug of the infusion container 9.
随后,旋转电机31可驱动主基板5转动,使西林瓶8的胶塞朝下,同时使输液容器9的出口朝下,进而使输液容器9内部的液体淹没穿刺器46的针孔。Subsequently, the rotating motor 31 can drive the main substrate 5 to rotate, so that the rubber stopper of the vial 8 faces downward, and at the same time the outlet of the infusion container 9 faces downward, so that the liquid inside the infusion container 9 floods the needle hole of the piercer 46.
然后,蠕动泵工作,通过一溶配药通道将输液容器10内的药液快速泵入西林瓶8中,随后或同时,通过另一溶配药通道将西林瓶8内的药液泵出,从而在西林瓶8和输液容器9之间形成循环回流状态,在西林瓶8内形成激烈的湍流,持续剧烈扰动西林瓶8内的药液和未溶解的药物,且通过大量输液持续动态的泵入、泵出,西林瓶8内有限容积的溶液的浓度被不断快速稀 释,从而使药物加快溶解。在药液循环回流的同时,可驱动西林瓶8旋转,并且第一纵向驱动电机23可带动第一承接架12纵向往复移动,同时保证穿刺器45的针孔处在西林瓶8内,从而使插入西林瓶8的穿刺器45喷射出的溶液可覆盖西林瓶8的内表面。并行地,可转动主基板5和/或驱动震动机构,促进药物溶解并平衡西林瓶8和输液容器9内的气压,对于难溶药物的溶解有极大的促进作用。药物完全溶解后,若溶配药器10的穿刺器45插入西林瓶8的底部,将主基板5旋转至西林瓶5胶塞向上,将西林瓶8内的药液完全泵入输液容器9内;若穿刺器45刚刺穿西林瓶8的胶塞时,将主基板5旋转至西林瓶8的胶塞向下,将西林瓶8内的药液完全泵入输液容器9内。Then, the peristaltic pump works to quickly pump the liquid medicine in the infusion container 10 into the vial 8 through a dissolving and dispensing channel, and then or at the same time, pump out the liquid medicine in the vial 8 through another dissolving and dispensing channel, thereby A circulating backflow state is formed between the vial 8 and the infusion container 9, and intense turbulence is formed in the vial 8, which continuously and violently disturbs the liquid and undissolved drugs in the vial 8, and is continuously and dynamically pumped through a large amount of infusion. When pumped out, the concentration of the limited volume of the solution in the vial 8 is continuously and rapidly diluted, so that the drug dissolves faster. While the liquid medicine is circulating back, the vial 8 can be driven to rotate, and the first longitudinal drive motor 23 can drive the first receiving frame 12 to move back and forth longitudinally, while ensuring that the needle hole of the trocar 45 is in the vial 8, so that The solution sprayed from the piercer 45 inserted into the vial 8 can cover the inner surface of the vial 8. In parallel, the main substrate 5 can be rotated and/or the vibration mechanism can be driven to promote the dissolution of the medicine and balance the air pressure in the vial 8 and the infusion container 9, which greatly promotes the dissolution of the insoluble medicine. After the medicine is completely dissolved, if the piercer 45 of the dissolving and dispensing device 10 is inserted into the bottom of the vial 8, the main substrate 5 is rotated to the rubber stopper of the vial 5, and the liquid medicine in the vial 8 is completely pumped into the infusion container 9; If the piercing device 45 has just pierced the rubber stopper of the vial 8, the main substrate 5 is rotated until the rubber stopper of the vial 8 is down, and the liquid medicine in the vial 8 is completely pumped into the infusion container 9.
(i)若盛瓶模块6上仅放置一个西林瓶8,则此时溶配药过程完成,转动主基板5回到原始体位,用第一纵向驱动电机23带动第一承接架12反向纵向位移(向下位移),用第二纵向驱动电机24带动第二承接架15反向纵向位移(向下位移),使溶配药器10的穿刺器45、46分别与西林瓶8和输液容器9分离,即完成配制操作;(i) If only one vial 8 is placed on the bottle holding module 6, the dissolving and dispensing process is completed at this time, and the main substrate 5 is rotated to return to the original position, and the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to reverse longitudinal displacement (Downward displacement), the second longitudinal drive motor 24 is used to drive the second receiving frame 15 to reverse longitudinal displacement (downward displacement), so that the piercers 45 and 46 of the dissolving and dispensing device 10 are separated from the vial 8 and the infusion container 9 respectively , The preparation operation is completed;
(ii)若盛瓶模块6上放置多个西林瓶8,(ii) If multiple vials 8 are placed on the bottle holding module 6,
第一纵向驱动电机23带动盛瓶模块6反向纵向位移,使穿刺器45与西林瓶8分离后,旋转电机39可带动第一承接杆40和盛瓶模块6转动,使盛瓶模块6上的下一西林瓶8转动至待配位;再用第一纵向驱动电机23带动第一承接架12纵向向上移动,使穿刺器45穿刺该下一西林瓶8的胶塞;随后,再按照上述溶配药程序将下一西林瓶8内的药物溶解转移至输液容器9中。The first longitudinal drive motor 23 drives the bottle holding module 6 to move in the reverse longitudinal direction, and after the piercer 45 is separated from the vial 8, the rotating motor 39 can drive the first receiving rod 40 and the bottle holding module 6 to rotate, so that the bottle holding module 6 is Next, the next vial 8 rotates to the position to be coordinated; then the first longitudinal drive motor 23 drives the first receiving frame 12 to move longitudinally upward, so that the piercer 45 pierces the rubber stopper of the next vial 8; then, follow the above The medicine dissolution procedure dissolves and transfers the medicine in the next vial 8 to the infusion container 9.
重复上述步骤(ii),直至所有的西林瓶8内的药物溶解转移至输液容器9中,此时溶配药过程完成。Repeat the above step (ii) until all the medicine in the vial 8 is dissolved and transferred to the infusion container 9, at which time the dissolving and dispensing process is completed.
溶配药过程完成后,用第一纵向驱动电机23带动第一承接架12向下位移,用第二纵向驱动电机24带动第二承接架15向下位移,使溶配药器10的穿刺器45、46分别与西林瓶8和输液容器9分离,即完成配制操作。转动主基板5回到原始体位。After the dissolving and dispensing process is completed, the first longitudinal drive motor 23 is used to drive the first supporting frame 12 to move downward, and the second longitudinal drive motor 24 is used to drive the second supporting frame 15 to move downwards, so that the piercers 45, 45, 46 is separated from the vial 8 and the infusion container 9 to complete the preparation operation. Rotate the main substrate 5 back to the original position.
采用图5所示的溶配药单元机进行该配置操作时,与采用图1至图4所示的溶配药单元机进行配制的不同之处在于:盛瓶模块49上放置多个西林瓶8时的步骤(ii)。When the dissolving and dispensing unit machine shown in FIG. 5 is used for this configuration operation, the difference from the dissolving and dispensing unit machine shown in FIGS. 1 to 4 is that a plurality of vials are placed on the bottle holding module 49 for 8 hours.的步骤(ii).
采用图5所示的溶配药单元机进行该配置操作时的步骤(ii)为:Step (ii) when the dissolving and dispensing unit machine shown in Figure 5 is used for this configuration operation is:
第一纵向驱动电机可带动盛瓶模块49向下位移,使穿刺器45与该西林瓶8分离;然后,第二横向驱动电机50可驱动盛瓶模块49横向移动,使盛瓶模块49横向移动至下一西林瓶8与穿刺器45纵向相对应;再用第一纵向驱动电机带动第一承接架纵向向上移动,使穿刺器45穿刺下一西林瓶8的胶塞;随后,再按照上述溶配药程序将下一西林瓶8内的药物溶解转移至输液容器9中。The first longitudinal drive motor can drive the bottle holding module 49 to move downwards to separate the piercer 45 from the vial 8; then, the second lateral drive motor 50 can drive the bottle holding module 49 to move laterally, so that the bottle holding module 49 can move laterally The next vial 8 corresponds to the piercing device 45 longitudinally; then the first longitudinal drive motor is used to drive the first receiving frame to move vertically upward, so that the piercing device 45 pierces the rubber stopper of the next vial 8; The dispensing procedure dissolves the medicine in the next vial 8 and transfers it to the infusion container 9.
重复上述步骤(ii),直至所有的西林瓶8内的药物泵入输液容器9中,此时溶配药过程完成。Repeat the above step (ii) until all the drugs in the vial 8 are pumped into the infusion container 9, at which time the dissolution and dispensing process is completed.
示例三:配制西林瓶装液体药物Example 3: Preparation of liquid medicine in vials
采用图1至图4所示的溶配药单元机进行配制的过程为:The process of using the dissolving and dispensing unit machine shown in Figure 1 to Figure 4 for preparation is:
首先,可将溶配药器10安装在溶配药器固定控制机构的运动夹块11上;然后,第三纵向驱动电机25、26可驱动运动夹块11向固定夹块37、38运动,至溶配药器10与固定夹块37、38接触,使溶配药器10被固定夹块37、38、运动夹块11共同夹持固定,穿刺器45、46的位置固定,这时蠕动泵泵头35、36与弹性输液软管43、44成挤压和待驱动状态。First, the dissolving dispenser 10 can be installed on the moving clamp 11 of the fixing control mechanism of the dissolving dispenser; then, the third longitudinal drive motor 25, 26 can drive the moving clamp 11 to move to the fixed clamps 37, 38 until the dissolving The dispenser 10 is in contact with the fixed clamp blocks 37, 38, so that the dissolving dispenser 10 is clamped and fixed by the fixed clamp blocks 37, 38 and the moving clamp block 11. The positions of the piercers 45, 46 are fixed, and then the peristaltic pump head 35 , 36 and the elastic infusion hose 43, 44 are squeezed and ready to be driven.
将输液容器9定位固定至夹持模块7内。Position the infusion container 9 into the clamping module 7.
将西林瓶8放置至盛瓶模块6内,这时西林瓶8的胶塞向上,驱动盛瓶模块6的夹紧释放电机,将放置在盛瓶模块6内的西林瓶8夹紧并定位。Place the vial 8 in the bottle holding module 6, and at this time, the rubber stopper of the vial 8 upwards, driving the clamping release motor of the bottle holding module 6 to clamp and position the vial 8 placed in the bottle holding module 6.
其中,溶配药器10、输液容器9和西林瓶8的放置安装次序可以互换。Among them, the placing and installation sequence of the dissolving and dispensing device 10, the infusion container 9 and the vial 8 can be interchanged.
然后,水平运动机构可驱动溶配药装置水平位移,使溶配药器10两端穿刺器45、46的垂直轴心分别与盛瓶模块6上处于待配位的西林瓶8的轴心和输液容器9的插入口的轴心处于同一轴线上。Then, the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the vial 8 to be coordinated on the bottle module 6 and the infusion container The axis of the insertion port of 9 is on the same axis.
其次,第一纵向驱动电机23可带动第一承接架12纵向向上移动,并带动盛瓶模块6纵向向上位移,使溶配药器10的穿刺器45插入西林瓶8内,并且使穿刺器45尽可能地插入西林瓶8的瓶底处,也可设置为穿刺器45刚刺穿西林瓶8的胶塞;随后或同时,第二纵向驱动电机24可带动第二承接架15纵向向上位移,带动输液容器9纵向移动,使溶配药器10的穿刺器46刺 穿输液容器9的胶塞内。Secondly, the first longitudinal drive motor 23 can drive the first receiving frame 12 to move vertically upwards, and drive the bottle holding module 6 to move upwards longitudinally, so that the piercer 45 of the dissolving and dispensing device 10 is inserted into the vial 8, and the piercing device 45 is exhausted. Possibly inserted into the bottom of the vial 8, or it can be set as the piercing device 45 just pierced the rubber stopper of the vial 8; subsequently or at the same time, the second longitudinal drive motor 24 can drive the second receiving frame 15 to move upward in the longitudinal direction to drive The infusion container 9 moves longitudinally, so that the piercer 46 of the dissolving and dispensing device 10 pierces the rubber stopper of the infusion container 9.
然后,蠕动泵工作,按照医嘱定量,将西林瓶8内的药液泵入输液容器9中或将西林瓶8内的全部药液泵入输液容器9中。当穿刺器45刚刺穿西林瓶8的胶塞时,旋转电机31还可驱动主基板5转动,使西林瓶8胶塞向下;然后蠕动泵工作,按照医嘱定量将西林瓶8内的药液泵入输液容器9中或将西林瓶8内的全部药液泵入输液容器9中。Then, the peristaltic pump works to pump the liquid medicine in the vial 8 into the infusion container 9 or pump all the liquid medicine in the vial 8 into the infusion container 9 according to the doctor's order. When the puncture device 45 has just pierced the rubber stopper of the vial 8, the rotating motor 31 can also drive the main substrate 5 to rotate to make the rubber stopper of the vial 8 downward; then the peristaltic pump works and quantifies the medicine in the vial 8 according to the doctor’s instructions. The liquid is pumped into the infusion container 9 or all the liquid medicine in the vial 8 is pumped into the infusion container 9.
(i)若盛瓶模块6上仅放置一个西林瓶8,则此时溶配药过程完成,用第一纵向驱动电机23带动第一承接架12反向纵向位移(向下位移),用第二纵向驱动电机24带动第二承接架15反向纵向位移(向下位移),使溶配药器10的穿刺器45、46分别与西林瓶8和输液容器9分离,即完成配制操作;(i) If only one vial 8 is placed on the bottle holding module 6, the dissolving and dispensing process is completed at this time, the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to reverse longitudinal displacement (downward displacement), and the second The longitudinal drive motor 24 drives the reverse longitudinal displacement (downward displacement) of the second receiving frame 15 so that the piercers 45 and 46 of the dissolving and dispensing device 10 are separated from the vial 8 and the infusion container 9 respectively, and the preparation operation is completed;
(ii)若盛瓶模块6上放置多个西林瓶8,(ii) If multiple vials 8 are placed on the bottle holding module 6,
在第一纵向驱动电机23带动盛瓶模块6向下位移,使穿刺器45与西林瓶8分离后,旋转电机39可带动第一承接杆40和盛瓶模块6转动,使盛瓶模块6上的下一西林瓶8转动至待配位;再用第一纵向驱动电机23带动第一承接架12纵向向上移动,使穿刺器45穿刺该下一西林瓶8的胶塞;按照上述配药程序,再启动蠕动泵,按照医嘱将该下一西林瓶8内所需的药物泵入输液容器9中。After the first longitudinal drive motor 23 drives the bottle holding module 6 to move downwards to separate the puncture device 45 from the vial 8, the rotating motor 39 can drive the first receiving rod 40 and the bottle holding module 6 to rotate, so that the bottle holding module 6 The next vial 8 of the next vial 8 is rotated to be coordinated; then the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to move longitudinally upwards, so that the piercing device 45 pierces the rubber stopper of the next vial 8; according to the above dispensing procedure, Then start the peristaltic pump, and pump the medicine needed in the next vial 8 into the infusion container 9 according to the doctor's order.
重复上述步骤(ii),按照医嘱直至所有的西林瓶8内所需的药物转移至输液容器9中,此时配药过程完成。Repeat the above step (ii) and follow the doctor's instructions until all the required drugs in the vial 8 are transferred to the infusion container 9, at which time the dispensing process is completed.
配药过程完成后,用第一纵向驱动电机23带动第一承接架12向下位移,第二纵向驱动电机24带动第二承接架15向下位移,使溶配药器10的穿刺器45、46分别与西林瓶8和输液容器9分离,即完成配制操作。After the dispensing process is completed, the first longitudinal drive motor 23 is used to drive the first receiving frame 12 to move downward, and the second longitudinal drive motor 24 drives the second receiving frame 15 to move downwards, so that the piercers 45 and 46 of the dissolving and dispensing device 10 are respectively Separate from the vial 8 and the infusion container 9 to complete the preparation operation.
采用图5所示的溶配药单元机进行该配置操作时,与采用图1至图4所示的溶配药单元机进行配制的不同之处在于:盛瓶模块49上放置多个西林瓶8时的步骤(ii)。When the dissolving and dispensing unit machine shown in FIG. 5 is used for this configuration operation, the difference from the dissolving and dispensing unit machine shown in FIGS. 1 to 4 is that a plurality of vials are placed on the bottle holding module 49 for 8 hours.的步骤(ii).
采用图5所示的溶配药单元机进行该配置操作时的步骤(ii)为:Step (ii) when the dissolving and dispensing unit machine shown in Figure 5 is used for this configuration operation is:
第一纵向驱动电机带动盛瓶模块49向下位移,使穿刺器45与该西林瓶 8分离;然后,第二横向驱动电机50可驱动盛瓶模块49横向位移,使盛瓶模块49横向位移至下一西林瓶8与穿刺器45纵向相对应的位置;再用第一纵向驱动电机带动第一承接架纵向向上移动,使穿刺器45穿刺下一西林瓶8的胶塞;随后,启动蠕动泵,按照医嘱将西林瓶8内的所需药液泵入输液容器9内。The first longitudinal drive motor drives the bottle holding module 49 to move downwards to separate the piercer 45 from the vial 8; then, the second lateral drive motor 50 can drive the bottle holding module 49 to move laterally, so that the bottle holding module 49 moves laterally to The position of the next vial 8 corresponding to the longitudinal direction of the puncture 45; then the first longitudinal drive motor drives the first supporting frame to move vertically upwards, so that the puncture 45 punctures the rubber stopper of the next vial 8; then, the peristaltic pump is started , Pump the required medicinal solution in the vial 8 into the infusion container 9 according to the doctor's order.
重复上述步骤(ii),按照医嘱直至所有的西林瓶8内所需的药物泵入输液容器9中,此时配药过程完成。Repeat the above step (ii) and follow the doctor's instructions until all the required medicines in the vials 8 are pumped into the infusion container 9, at which time the dispensing process is completed.
示例四:并行配制安瓿瓶装药物和西林瓶装液体药物Example 4: Parallel preparation of ampoules and vials of liquid drugs
首先,可将溶配药器10安装在溶配药器固定控制机构的运动夹块11上;然后,第三纵向驱动电机25、26可驱动运动夹块11向固定夹块37、38运动,至溶配药器10与固定夹块37、38接触,夹紧,这时蠕动泵泵头35、36与弹性输液软管43、44成挤压和待驱动状态。First, the dissolving dispenser 10 can be installed on the moving clamp 11 of the fixing control mechanism of the dissolving dispenser; then, the third longitudinal drive motor 25, 26 can drive the moving clamp 11 to move to the fixed clamps 37, 38 until the dissolving The dispenser 10 is in contact with the fixed clamp blocks 37, 38 and clamped. At this time, the pump heads 35, 36 of the peristaltic pump and the elastic infusion hoses 43, 44 are in a squeezed and ready-to-drive state.
将输液容器9定位固定至夹持模块7内。Position the infusion container 9 into the clamping module 7.
将安瓿瓶54和西林瓶8放置至盛瓶模块6内,这时安瓿瓶54的开口向上,西林瓶8的胶塞向上。驱动盛瓶模块6的夹紧释放电机,将放置在盛瓶模块6内的安瓿瓶54和西林瓶8夹紧并定位。Place the ampoule 54 and the vial 8 in the bottle holding module 6, at this time, the opening of the ampoule 54 is upward, and the rubber stopper of the vial 8 is upward. The clamping release motor of the bottle holding module 6 is driven to clamp and position the ampoule 54 and the vial 8 placed in the bottle holding module 6.
其中,溶配药器10、输液容器9、以及安瓿瓶54和西林瓶8的放置安装次序可以互换。Among them, the dissolving and dispensing device 10, the transfusion container 9, and the ampule 54 and the vial 8 are placed and installed in an interchangeable order.
然后,水平运动机构可驱动溶配药装置水平位移,使溶配药器10两端的穿刺器45、46垂直轴心分别盛瓶模块6上处于待配位的安瓿瓶54的轴心和输液容器9的插入口的轴心处于同一轴线上。Then, the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are on the bottle holding module 6 and the axis of the ampoule 54 to be coordinated and the infusion container 9 respectively. The axis of the insertion port is on the same axis.
然后,按照示例一中的安瓿瓶的溶配药操作进行,使盛瓶模块6中的安瓿瓶54先完成溶配药操作。Then, follow the dissolving and dispensing operation of the ampoule in Example 1, so that the ampoule 54 in the bottle holding module 6 completes the dissolving and dispensing operation first.
随后,按照示例二或示例三中的西林瓶8的溶配药操作进行,使盛瓶模块6中的西林瓶8完成溶配药操作。Subsequently, the dissolving and dispensing operation of the vial 8 in Example 2 or 3 is performed, so that the vial 8 in the bottle holding module 6 completes the dissolving and dispensing operation.
溶配药过程完成后,用第一纵向驱动电机23带动第一承接架12向下位移,用第二纵向驱动电机24带动第二承接架15向下位移,使溶配药器10的穿刺器45、46分别与西林瓶8和输液容器9分离,即完成配制操作。After the dissolving and dispensing process is completed, the first longitudinal drive motor 23 is used to drive the first supporting frame 12 to move downward, and the second longitudinal drive motor 24 is used to drive the second supporting frame 15 to move downwards, so that the piercers 45, 45, 46 is separated from the vial 8 and the infusion container 9 to complete the preparation operation.
在溶配药过程中,如果西林瓶8内是液体药物,不需溶解,也可以先进行西林瓶8的溶配药操作,然后再进行安瓿瓶54的溶配药操作;或者,西林瓶8和安瓿瓶54有多瓶时,交替进行西林瓶8和安瓿瓶54的溶配药操作。In the process of dissolving and dispensing, if the vial 8 contains liquid medicine and does not need to be dissolved, the dissolving and dispensing operation of the vial 8 can be performed first, and then the dissolving and dispensing operation of the ampoule 54; or, the vial 8 and the ampoule When 54 has multiple bottles, the dissolving and dispensing operations of the vial 8 and the ampoule 54 are alternately performed.
示例五:配制含专用溶媒的药物Example 5: Preparation of drugs containing special solvents
采用图1至图4所示的溶配药单元机进行配制的过程为:The process of using the dissolving and dispensing unit machine shown in Figure 1 to Figure 4 for preparation is:
首先,可将溶配药器10安装在运动夹块11上;然后,第三驱动电机25、26可驱动运动夹块11向固定夹块37、38运动,至溶配药器10与固定夹块37、38接触,使溶配药器10被固定夹块37、38、运动夹块11共同夹持固定,穿刺器45、46的位置固定,这时蠕动泵泵头35、36与弹性输液软管43、44成挤压和待驱动状态。First, the dissolving and dispensing device 10 can be installed on the moving clamp 11; then, the third drive motor 25, 26 can drive the movable clamping block 11 to move to the fixed clamping blocks 37, 38 to the dissolving and dispensing device 10 and the fixed clamping block 37 , 38 contact, so that the dissolving and dispensing device 10 is clamped and fixed by the fixed clamp block 37, 38, and the moving clamp block 11, the position of the puncture device 45, 46 is fixed, then the peristaltic pump head 35, 36 and the elastic infusion hose 43 , 44 into squeezed and to be driven state.
将输液容器10定位固定至夹持模块7内。The infusion container 10 is positioned and fixed in the clamping module 7.
将西林瓶8及配套使用的专用溶媒药瓶放置至盛瓶模块6内,这时西林瓶8的胶塞向上。驱动盛瓶模块6的夹紧释放电机,将放置在盛瓶模块6内的西林瓶和专用溶配药瓶夹紧并定位。Place the vial 8 and the matched special solvent medicine bottle into the bottle holding module 6, and the rubber stopper of the vial 8 is upward. The clamping release motor of the bottle holding module 6 is driven to clamp and position the vial and the special dissolving medicine bottle placed in the bottle holding module 6.
溶配药器10、输液容器9、以及西林瓶8和专用溶媒药瓶的放置安装次序可以互换。The dissolving and dispensing device 10, the infusion container 9, and the vial 8 and the special solvent medicine bottle are placed and installed in an interchangeable order.
然后,水平运动机构可驱动溶配药装置水平位移,使溶配药器10两端的穿刺器45、46的垂直轴心分别与盛瓶模块6上处于待配位西林瓶8的轴心和专用溶媒药瓶的轴心处于同一轴线上。Then, the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at the two ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the vial 8 to be coordinated and the special solvent on the bottle module 6 The axis of the bottle is on the same axis.
其次,第一纵向驱动电机23带动第一承接架12纵向向上移动,并带动盛瓶模块6纵向向上位移,使溶配药器10的穿刺器45插入西林瓶8内,同时溶配药器10的另一穿刺器46插入专用溶媒药瓶内,并且使穿刺器46尽可能地插入专用溶媒药瓶的瓶底处。Secondly, the first longitudinal drive motor 23 drives the first receiving frame 12 to move upwards longitudinally, and drives the bottle holding module 6 to move upwards longitudinally, so that the piercer 45 of the dissolving and dispensing device 10 is inserted into the vial 8, and the other part of the dispensing device 10 is simultaneously melted. A puncture device 46 is inserted into the special solvent medicine bottle, and the puncture device 46 is inserted into the bottom of the special solvent medicine bottle as much as possible.
然后,蠕动泵工作,通过一溶配药通道将专用溶媒药瓶内的溶液快速泵入西林瓶8中;随后/同时,可通过另一溶配药通道将西林瓶8内的药液泵出至专用溶媒药瓶,从而在西林瓶8和专用溶媒药瓶之间形成循环回流状态,在西林瓶8内形成激烈的湍流,持续剧烈扰动西林瓶内的药液和未溶解的药物,且通过溶液持续动态的泵入、泵出,西林瓶8内有限容积的溶液的浓度 被不断快速稀释,从而使药物加快溶解。在药液循环回流的同时,可驱动西林瓶8旋转,并且第一纵向驱动电机23可带动第一承接架12纵向往复移动,同时保证穿刺器45的针孔处在西林瓶8内,穿刺器46的针孔处在专用溶媒药瓶内,从而使插入西林瓶8的穿刺器45喷射出的溶液可覆盖西林瓶8的内表面。并行地,可转动主基板5和/或驱动震动机构,对于难溶药物的溶解有极大的促进作用。药物完全溶解后,专用溶媒内的药液全部泵入西林瓶8内。Then, the peristaltic pump works and quickly pumps the solution in the special solvent medicine bottle into the vial 8 through a dissolving and dispensing channel; subsequently/at the same time, the liquid in the vial 8 can be pumped out to the dedicated via another dissolving and dispensing channel The solvent medicine bottle forms a circulating backflow state between the vial 8 and the special solvent medicine bottle, and intense turbulence is formed in the vial 8, which continuously violently disturbs the liquid medicine and undissolved medicine in the vial, and continues through the solution With dynamic pumping in and out, the concentration of the limited volume solution in the vial 8 is continuously and rapidly diluted, so that the drug dissolves faster. While the liquid medicine is circulating back, the vial 8 can be driven to rotate, and the first longitudinal drive motor 23 can drive the first supporting frame 12 to move back and forth longitudinally, while ensuring that the needle hole of the trocar 45 is in the vial 8. The needle hole of 46 is in the special solvent medicine bottle, so that the solution sprayed from the puncture device 45 inserted into the vial 8 can cover the inner surface of the vial 8. In parallel, the main substrate 5 can be rotated and/or the vibration mechanism can be driven, which greatly promotes the dissolution of insoluble drugs. After the medicine is completely dissolved, all the liquid medicine in the special solvent is pumped into the vial 8.
然后,第一纵向驱动电机23可带动盛瓶模块6向下位移,使穿刺器45、46分别与西林瓶8和专用溶媒药瓶分离。Then, the first longitudinal drive motor 23 can drive the bottle holding module 6 to move downward, so that the piercers 45 and 46 are separated from the vial 8 and the special solvent medicine bottle respectively.
随后,水平运动机构可驱动溶配药装置水平位移,使溶配药器10两端的穿刺器45、46垂直轴心分别与盛瓶模块6上处于待配位的西林瓶8的轴心和输液容器9的插入口轴心处于同一轴线上。Subsequently, the horizontal movement mechanism can drive the dissolving and dispensing device to move horizontally, so that the vertical axes of the piercers 45 and 46 at both ends of the dissolving and dispensing device 10 are respectively aligned with the axis of the vial 8 to be coordinated on the bottle module 6 and the infusion container 9 The axis of the insertion port is on the same axis.
然后,第一纵向驱动电机23可带动第一承接架12纵向向上移动,并带动盛瓶模块6纵向向上位移,使溶配药器10的穿刺器45插入西林瓶8内,并且使穿刺器45尽可能地插入西林瓶8的瓶底处,也可设置为穿刺器45刚刺穿西林瓶8的胶塞;随后或同时,第二纵向驱动电机24可带动第二承接架15纵向向上位移,带动输液容器9纵向移动,使溶配药器10的穿刺器46刺穿输液容器9的胶塞内。Then, the first longitudinal drive motor 23 can drive the first receiving frame 12 to move vertically upwards, and drive the bottle holding module 6 to move vertically upwards, so that the puncture 45 of the dissolving and dispensing device 10 is inserted into the vial 8, and the puncture 45 is exhausted. Possibly inserted into the bottom of the vial 8, or it can be set as the piercing device 45 just pierced the rubber stopper of the vial 8; subsequently or at the same time, the second longitudinal drive motor 24 can drive the second receiving frame 15 to move upward in the longitudinal direction to drive The infusion container 9 moves longitudinally, so that the piercer 46 of the dissolving and dispensing device 10 pierces the rubber stopper of the infusion container 9.
然后,蠕动泵工作,按照医嘱定量将西林瓶8内的药液泵入输液容器9中,或将西林瓶8内的全部药液泵入输液容器9中。当穿刺器45刚刺穿西林瓶8的胶塞时,还可将主基板5旋转,使西林瓶8的胶塞向下,然后蠕动泵工作,按照医嘱定量将西林瓶8内的药液泵入输液容器9中或将西林瓶8内的全部药液泵入输液容器9中。Then, the peristaltic pump works to pump the liquid medicine in the vial 8 into the infusion container 9 according to the doctor's order, or pump all the liquid medicine in the vial 8 into the infusion container 9. When the puncture device 45 has just pierced the rubber stopper of the vial 8, the main substrate 5 can also be rotated to make the rubber stopper of the vial 8 downward, and then the peristaltic pump will work to quantitatively pump the liquid medicine in the vial 8 according to the doctor’s instructions Into the infusion container 9 or pump all the liquid medicine in the vial 8 into the infusion container 9.
此时溶配药过程完成,用第一纵向驱动电机24带动第一承接架12反向纵向位移(向下位移),用第二纵向驱动电机24带动第二承接架15反向纵向位移(向下位移),使溶配药器10的穿刺器45、46分别与西林瓶8和输液容器9分离,即完成含专用溶媒药物的配制操作。At this time, the process of dissolving and dispensing is completed. The first longitudinal drive motor 24 drives the first receiving frame 12 to reverse longitudinal displacement (downward displacement), and the second longitudinal drive motor 24 drives the second longitudinal displacement (downward) of the second receiving frame 15 Displacement), the piercers 45 and 46 of the dissolving and dispensing device 10 are separated from the vial 8 and the infusion container 9 respectively, and the compounding operation of the medicine containing the special solvent is completed.
采用图5所示的溶配药单元机进行该配置操作时的步骤与图1至图4所示的溶配药单元机进行配制操作时的步骤基本相同。The steps when the dissolving and dispensing unit machine shown in FIG. 5 is used for this configuration operation are basically the same as the steps when the dissolving and dispensing unit machine shown in FIGS. 1 to 4 is used for the preparation operation.
本申请实施例中的部件运动均可由自动化溶配药系统进行自动控制。The movement of the components in the embodiments of the present application can be automatically controlled by the automatic dissolving and dispensing system.
上述的溶配药单元机的实施例及五个溶配药的示例显示,溶配药单元机可进行快速溶配药品的操作并可实现自动化溶配,具备为每个医嘱独立完成溶配药物的功能,能极大提高难溶药物的溶解配制速度,并有配制含专用溶媒药物的功能。在配制药物过程中,医护人员无需接触药品,无需对输液容器的胶塞和西林瓶的胶塞反复进行穿刺,在配药过程中有效减少胶塞颗粒脱离、外界微粒、微生物的污染,在配药过程中尽可能减少药物溅出和挥发,有效降低配药过程中药物对医护人员的伤害,最大限度地降低了药品暴露和药品二次污染,提高了输液安全性。本申请实施例的溶配药单元机的人机界面友好,在溶配药过程中,溶配药器的安装操作、第一盛药容器的安装操作和第二盛药容器的安装操作,都是面向操作人员的,操作十分方便;本申请实施例的溶配药单元机中,主要的不易清洁和消毒的运动机构均与溶配药器、第一盛药容器和第二盛药容器分置于主基板和副基板的两侧安装,且运动机构均被封闭,使本申请实施例的溶配药单元机易于清洁、消毒。本申请实施例的溶配药单元机实现了自动化、高效率、无污染的配药,在保护医护人员和患者的健康的同时,大大降低医护人员的劳动强度,可对社会和患者带来较大的益处。The above-mentioned embodiment of the dissolving and dispensing unit machine and five examples of dissolving and dispensing medicine show that the dissolving and dispensing unit machine can quickly dissolve and dispense medicines and realize automatic dispensing, and has the function of independently dissolving medicines for each doctor's order. It can greatly improve the dissolution and preparation speed of insoluble drugs, and has the function of preparing drugs containing special solvents. In the process of drug preparation, medical staff do not need to touch the drugs, and do not need to repeatedly puncture the rubber stopper of the infusion container and the rubber stopper of the vial, effectively reducing the separation of rubber stopper particles, external particles, and microbial contamination during the dispensing process. It minimizes drug splashing and volatilization, effectively reduces the harm of drugs to medical staff during the dispensing process, minimizes drug exposure and drug secondary pollution, and improves the safety of infusion. The man-machine interface of the dissolving and dispensing unit machine of the embodiment of the application is friendly. During the dissolving and dispensing process, the installation operation of the dissolving and dispensing device, the installation operation of the first medicine container and the installation operation of the second medicine container are all operation-oriented For personnel, the operation is very convenient; in the dissolving and dispensing unit machine of the embodiment of the application, the main movement mechanisms that are not easy to clean and sterilize are separated from the dissolving and dispensing device, the first medicine container and the second medicine container on the main substrate and Both sides of the sub-base plate are installed, and the movement mechanism is closed, so that the dissolving and dispensing unit machine of the embodiment of the present application is easy to clean and disinfect. The dissolving and dispensing unit machine of the embodiment of the application realizes automatic, high-efficiency, and pollution-free dispensing. While protecting the health of medical staff and patients, it greatly reduces the labor intensity of medical staff and can bring greater impact to society and patients benefit.
在本申请实施例中的描述中,术语“上”、“下”、“前”、“后”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本申请实施例和简化描述,而不是指示或暗示所指的结构具有特定的方位、以特定的方位构造和操作,因此不能理解为对本申请实施例的限制。In the description of the embodiments of this application, the terms "upper", "lower", "front", "rear", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for ease of description The embodiments and simplified descriptions of the present application do not indicate or imply that the structure referred to has a specific orientation, is constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the embodiments of the present application.
在本申请实施例的描述中,术语“安装”、“连接”、“固定”等均应做广义理解,例如,“连接”可以是固定连接,或可拆卸连接,或一体地连接;可以是直接相连,或通过中间媒介间接相连。对于本领域的普通技术人员而言,可以根据实际情况理解上述术语在本申请实施例中的含义。In the description of the embodiments of the present application, the terms "installation", "connection", "fixation", etc. should be understood in a broad sense. For example, "connection" can be a fixed connection, a detachable connection, or an integral connection; Connect directly or indirectly through an intermediary. For those of ordinary skill in the art, the meaning of the above terms in the embodiments of the present application can be understood according to actual conditions.
虽然本申请实施例所揭露的实施方式如上,但所述的内容仅为便于理解本申请实施例而采用的实施方式,并非用以限定本申请实施例。任何本申请实施例所属领域内的技术人员,在不脱离本申请实施例所揭露的精神和范围的前提下,可以在实施的形式及细节上进行任何的修改与变化,但本申请实施例的专利保护范围,仍须以所附的权利要求书所界定的范围为准。Although the implementation manners disclosed in the embodiments of the present application are as described above, the content described is only the implementation manners used to facilitate the understanding of the embodiments of the present application, and are not intended to limit the embodiments of the present application. Any person skilled in the art of the embodiments of this application can make any modifications and changes in the implementation form and details without departing from the spirit and scope disclosed in the embodiments of this application. The scope of patent protection is still subject to the scope defined by the appended claims.

Claims (13)

  1. 一种溶配药单元机,包括:A dissolving and dispensing unit machine includes:
    主基板;Main substrate
    溶配药装置,安装在所述主基板上,包括溶配药器和蠕动泵,所述溶配药器包括至少一个溶配药通道,每一个所述溶配药通道包括两个穿刺器和连接所述两个穿刺器的弹性输液软管,所述蠕动泵设置成挤压所述弹性输液软管;The dissolving and dispensing device is installed on the main substrate and includes a dissolving and dispensing device and a peristaltic pump. The dissolving and dispensing device includes at least one dissolving and dispensing channel, and each of the dissolving and dispensing channels includes two punctures and connecting the two The elastic infusion hose of the trocar, the peristaltic pump is arranged to squeeze the elastic infusion hose;
    两个固定模块,安装在所述主基板上,设置成固定盛药容器,所述溶配药装置位于上方,所述两个固定模块位于下方;或者,所述两个固定模块位于上方,所述溶配药装置位于下方;Two fixing modules are installed on the main substrate and configured to fix the medicine container, the dissolving and dispensing device is located above, and the two fixing modules are located below; or, the two fixing modules are located above, the The dissolving and dispensing device is located below;
    水平运动机构,设置成带动所述溶配药装置在水平面内运动,使所述溶配药装置的所述两个穿刺器与至少一个所述固定模块上固定的两个所述盛药容器纵向对应;和The horizontal movement mechanism is configured to drive the medicine dissolving and dispensing device to move in a horizontal plane, so that the two piercers of the medicine dissolving and dispensing device correspond longitudinally with the two medicine containers fixed on at least one of the fixing modules; with
    纵向运动机构,设置成带动所述两个固定模块和所述溶配药装置中的一者纵向移动,使所述穿刺器穿刺所述盛药容器或与所述盛药容器分离。The longitudinal movement mechanism is configured to drive one of the two fixing modules and the medicine dissolving device to move longitudinally, so that the piercing device pierces the medicine container or is separated from the medicine container.
  2. 如权利要求1所述的溶配药单元机,其中,所述溶配药装置还包括副基板,所述溶配药器和所述蠕动泵均安装在所述副基板上,所述副基板与所述主基板活动连接,所述水平运动机构设置成带动所述副基板运动。The dissolving and dispensing unit machine according to claim 1, wherein the dissolving and dispensing device further comprises a sub-base, and the dissolving and dispensing device and the peristaltic pump are both mounted on the sub-base, and the sub-base and the The main substrate is movably connected, and the horizontal movement mechanism is configured to drive the auxiliary substrate to move.
  3. 如权利要求2所述的溶配药单元机,其中,所述水平运动机构为线性移动机构,设置成带动所述副基板直线移动。3. The medicine dissolving and dispensing unit machine according to claim 2, wherein the horizontal movement mechanism is a linear movement mechanism configured to drive the auxiliary substrate to move linearly.
  4. 如权利要求3所述的溶配药单元机,其中,所述水平运动机构包括横向导轨、横向滑块和横向驱动模块,所述横向驱动模块和所述横向导轨安装在所述主基板上,所述横向滑块与所述横向导轨配合,且所述横向滑块与所述副基板连接,所述横向驱动模块设置成驱动所述横向滑块沿所述横向导轨运动。The dissolving and dispensing unit machine according to claim 3, wherein the horizontal movement mechanism includes a horizontal rail, a horizontal sliding block and a horizontal drive module, and the horizontal drive module and the horizontal rail are mounted on the main substrate, so The horizontal slider is matched with the horizontal rail, and the horizontal slider is connected with the auxiliary substrate, and the horizontal driving module is configured to drive the horizontal slider to move along the horizontal rail.
  5. 如权利要求2所述的溶配药单元机,其中,所述水平运动机构为水平旋转机构,设置成带动所述副基板在水平面内进行旋转运动。The dissolving and dispensing unit machine according to claim 2, wherein the horizontal movement mechanism is a horizontal rotation mechanism configured to drive the sub-substrate to perform a rotational movement in a horizontal plane.
  6. 如权利要求1至5中任一项所述的溶配药单元机,其中,一个所述固定模块包括多个固定单元,每一个所述固定单元设置成固定一个所述盛药容器,所述水平运动机构设置成带动所述溶配药装置水平运动直至所述两个穿刺器与两个所述固定单元一一纵向对应。The medicine dissolving and dispensing unit machine according to any one of claims 1 to 5, wherein one fixing module includes a plurality of fixing units, and each fixing unit is configured to fix one medicine container, and the horizontal The movement mechanism is arranged to drive the dissolving and dispensing device to move horizontally until the two piercers and the two fixing units correspond one-to-one longitudinally.
  7. 如权利要求6所述的溶配药单元机,其中,所述固定模块还包括固定架和线性驱动装置,多个所述固定单元固定在所述固定架上且呈线性排列,所述线性驱动装置设置成驱动所述固定架线性移动;The dissolving and dispensing unit machine according to claim 6, wherein the fixing module further comprises a fixing frame and a linear driving device, and a plurality of the fixing units are fixed on the fixing frame and arranged linearly, and the linear driving device Set to drive the fixed frame to move linearly;
    或者,所述固定模块还包括固定架和旋转驱动装置,多个所述固定单元固定在所述固定架上且呈圆周排列,所述旋转驱动装置设置成驱动所述固定架旋转运动。Alternatively, the fixing module further includes a fixing frame and a rotation driving device, a plurality of the fixing units are fixed on the fixing frame and arranged in a circle, and the rotation driving device is configured to drive the fixing frame to rotate.
  8. 如权利要求7所述的溶配药单元机,其中,所述固定模块的线性驱动装置或旋转驱动装置被密封罩包裹。The dissolving and dispensing unit machine according to claim 7, wherein the linear drive device or the rotation drive device of the fixed module is wrapped by a sealing cover.
  9. 如权利要求2至8中任一项所述的溶配药单元机,其中,所述纵向运动机构设置成带动所述两个固定模块纵向移动,所述两个固定模块位于所述主基板的前侧,所述纵向运动机构位于所述主基板的后侧,所述纵向运动机构通过承接架与所述两个固定模块连接,所述主基板上设有纵向滑槽,所述承接架穿过所述纵向滑槽;The dissolving and dispensing unit machine according to any one of claims 2 to 8, wherein the longitudinal movement mechanism is configured to drive the two fixed modules to move longitudinally, and the two fixed modules are located in front of the main substrate. Side, the longitudinal movement mechanism is located on the rear side of the main base plate, the longitudinal movement mechanism is connected to the two fixed modules through a supporting frame, the main base plate is provided with a longitudinal chute through which the supporting frame passes The longitudinal chute;
    所述主基板的后侧固定有第一机罩,所述第一机罩罩住所述纵向运动机构。A first hood is fixed on the rear side of the main substrate, and the first hood covers the longitudinal movement mechanism.
  10. 如权利要求9所述的溶配药单元机,其中,所述纵向运动机构包括第一纵向运动机构和第二纵向运动机构,所述承接架包括第一承接架和第二承接架,所述纵向滑槽包括第一纵向滑槽和第二纵向滑槽,所述第一纵向运动机构通过所述第一承接架与所述两个固定模块中的第一固定模块连接,所述第一承接架穿过所述第一纵向滑槽,所述第二纵向运动机构通过所述第二承接架与所述两个固定模块中的第二固定模块连接,所述第二承接架穿过所述第二纵向滑槽。The dissolving and dispensing unit machine according to claim 9, wherein the longitudinal movement mechanism comprises a first longitudinal movement mechanism and a second longitudinal movement mechanism, and the supporting frame comprises a first supporting frame and a second supporting frame, and the longitudinal movement mechanism The chute includes a first longitudinal chute and a second longitudinal chute. The first longitudinal movement mechanism is connected to the first of the two fixed modules through the first supporting frame. The first supporting frame Passing through the first longitudinal chute, the second longitudinal movement mechanism is connected to the second fixed module of the two fixed modules through the second supporting frame, and the second supporting frame passes through the first Two longitudinal chutes.
  11. 如权利要求9或10所述的溶配药单元机,其中,所述溶配药装置位于所述两个固定模块的上方,所述水平运动机构位于所述主基板的后侧、所 述纵向运动机构的上方;The dissolving and dispensing unit machine according to claim 9 or 10, wherein the dissolving and dispensing device is located above the two fixed modules, the horizontal movement mechanism is located on the rear side of the main substrate, and the longitudinal movement mechanism Above
    所述第一机罩罩住所述水平运动机构,所述第一机罩的上部设有安装槽,所述副基板穿过所述安装槽后与所述水平运动机构连接。The first hood covers the horizontal movement mechanism, an upper part of the first hood is provided with a mounting groove, and the auxiliary base plate is connected to the horizontal movement mechanism after passing through the mounting groove.
  12. 如权利要求2至11中任一项所述的溶配药单元机,其中,所述副基板上固定有第二机罩,所述第二机罩罩住所述溶配药装置。The medicine dissolving and dispensing unit machine according to any one of claims 2 to 11, wherein a second machine cover is fixed on the sub-base plate, and the second machine cover covers the medicine dissolving and dispensing device.
  13. 如权利要求1至12中任一项所述的溶配药单元机,还包括基座和旋转电机,所述主基板与所述基座转动连接,所述旋转电机设置成驱动所述主基板相对所述基座旋转。The dissolving and dispensing unit machine according to any one of claims 1 to 12, further comprising a base and a rotating motor, the main substrate is rotatably connected to the base, and the rotating motor is configured to drive the main substrate to face each other The base rotates.
PCT/CN2020/074858 2019-02-15 2020-02-12 Medicine dissolving and dispensing unit machine WO2020164511A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201920202393.2 2019-02-15
CN201920202393.2U CN210078311U (en) 2019-02-15 2019-02-15 Dissolve unit machine of dispensing

Publications (1)

Publication Number Publication Date
WO2020164511A1 true WO2020164511A1 (en) 2020-08-20

Family

ID=69470710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2020/074858 WO2020164511A1 (en) 2019-02-15 2020-02-12 Medicine dissolving and dispensing unit machine

Country Status (2)

Country Link
CN (1) CN210078311U (en)
WO (1) WO2020164511A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112206152B (en) * 2020-10-22 2023-05-12 西南医科大学 Multifunctional automatic dispensing device for clinical pharmacy transfusion
CN113509869A (en) * 2021-08-06 2021-10-19 四川省医学科学院·四川省人民医院 A xining bottle bearing subassembly for dispensing machine people

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103028161A (en) * 2012-01-17 2013-04-10 深圳市卫邦科技有限公司 Automatic dispensing method and automatic dispensing system
JP2013184027A (en) * 2012-03-12 2013-09-19 Hitachi Aloka Medical Ltd Liquid medicine dispensing apparatus
CN106377425A (en) * 2016-08-31 2017-02-08 深圳市博为医疗机器人有限公司 Intelligent dispensing equipment
CN106955235A (en) * 2017-02-23 2017-07-18 湖南千山制药机械股份有限公司 Automatic dispensation apparatus
CN206508252U (en) * 2016-11-24 2017-09-22 上海螭宿医药科技有限公司 Molten dispensing system is automated with the molten unit machine that makes up a prescription
CN206980625U (en) * 2017-07-20 2018-02-09 上海螭宿医药科技有限公司 The molten unit machine that makes up a prescription
CN207838731U (en) * 2017-08-16 2018-09-11 上海合宿医疗科技有限公司 Molten dispensing system
CN108852832A (en) * 2018-07-17 2018-11-23 天津屹诺康源医药科技有限公司 A kind of automatic injection drug liquid make-up machine

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103028161A (en) * 2012-01-17 2013-04-10 深圳市卫邦科技有限公司 Automatic dispensing method and automatic dispensing system
JP2013184027A (en) * 2012-03-12 2013-09-19 Hitachi Aloka Medical Ltd Liquid medicine dispensing apparatus
CN106377425A (en) * 2016-08-31 2017-02-08 深圳市博为医疗机器人有限公司 Intelligent dispensing equipment
CN206508252U (en) * 2016-11-24 2017-09-22 上海螭宿医药科技有限公司 Molten dispensing system is automated with the molten unit machine that makes up a prescription
CN106955235A (en) * 2017-02-23 2017-07-18 湖南千山制药机械股份有限公司 Automatic dispensation apparatus
CN206980625U (en) * 2017-07-20 2018-02-09 上海螭宿医药科技有限公司 The molten unit machine that makes up a prescription
CN207838731U (en) * 2017-08-16 2018-09-11 上海合宿医疗科技有限公司 Molten dispensing system
CN108852832A (en) * 2018-07-17 2018-11-23 天津屹诺康源医药科技有限公司 A kind of automatic injection drug liquid make-up machine

Also Published As

Publication number Publication date
CN210078311U (en) 2020-02-18

Similar Documents

Publication Publication Date Title
WO2018095331A1 (en) Dissolving and dispensing unit, dissolving and dispensing system, and dissolving and dispensing method
WO2020164511A1 (en) Medicine dissolving and dispensing unit machine
CN103006436B (en) A kind of automated dispensing machine people's system and method
CN205391352U (en) Medicine dispensing machine ware people
CN202537953U (en) Peristaltic pump and automatic dispensing system comprising same
WO2021189883A1 (en) Apparatus for continuously dispensing medicine from multiple medicine bottles and medicine dispensing method thereof
CN108969358B (en) Automatic dispensing device, transfer head and dispensing method
CN110882162A (en) Automatic medicine dispensing robot
CN106473924B (en) A kind of automation molten dispensing system molten dispensing unit machine and molten dosage
CN103588161A (en) Tabletop type medical dispensing operation station
CN112206152B (en) Multifunctional automatic dispensing device for clinical pharmacy transfusion
CN211326906U (en) Automatic medicine dispensing robot
CN209548389U (en) A kind of automatic dispensation apparatus
CN114533552A (en) Automatic transfusion medicine dispensing machine
CN217745057U (en) XiLin bottle encapsulation medicine allotment robot
CN111603388B (en) Multidimensional dispensing robot
WO2017162120A1 (en) Medicine dissolving and dispensing apparatus
CN208726278U (en) Molten dispensing unit machine
WO2016202010A1 (en) Semi-automatic medicine mixing machine
CN219110241U (en) Medicine dispenser for static dispensing center
CN114983821A (en) Automatic quantitative dispensing robot and automatic dispensing method thereof
CN218908253U (en) Combined container for clinical pharmacist to dispense medicine
CN218900200U (en) Intravenous transfusion liquid preparation device
CN217548555U (en) Quick dispensing device
CN219804528U (en) Electric dispensing device

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20756620

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 20756620

Country of ref document: EP

Kind code of ref document: A1