WO2020158644A1 - Dispositif de tomosynthèse et procédé pour l'entraîner - Google Patents

Dispositif de tomosynthèse et procédé pour l'entraîner Download PDF

Info

Publication number
WO2020158644A1
WO2020158644A1 PCT/JP2020/002697 JP2020002697W WO2020158644A1 WO 2020158644 A1 WO2020158644 A1 WO 2020158644A1 JP 2020002697 W JP2020002697 W JP 2020002697W WO 2020158644 A1 WO2020158644 A1 WO 2020158644A1
Authority
WO
WIPO (PCT)
Prior art keywords
cold cathode
ray
ray sources
tomosynthesis
tomosynthesis device
Prior art date
Application number
PCT/JP2020/002697
Other languages
English (en)
Japanese (ja)
Inventor
均 桝谷
秀憲 監物
Original Assignee
ナノックス イメージング リミテッド
株式会社ナノックスイメージング
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ナノックス イメージング リミテッド, 株式会社ナノックスイメージング filed Critical ナノックス イメージング リミテッド
Publication of WO2020158644A1 publication Critical patent/WO2020158644A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J35/00—X-ray tubes
    • H01J35/02—Details
    • H01J35/04—Electrodes ; Mutual position thereof; Constructional adaptations therefor
    • H01J35/06—Cathodes
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05G—X-RAY TECHNIQUE
    • H05G1/00—X-ray apparatus involving X-ray tubes; Circuits therefor
    • H05G1/08—Electrical details
    • H05G1/70—Circuit arrangements for X-ray tubes with more than one anode; Circuit arrangements for apparatus comprising more than one X ray tube or more than one cathode

Definitions

  • the present invention relates to a tomosynthesis device using a plurality of cold cathode X-ray sources and a method of blinking these X-ray sources.
  • Tomosynthesis is one of the widely used methods for obtaining high-resolution tomographic images in X-ray fluoroscopy, and a plurality of objects obtained by scanning an object while irradiating X-rays in a certain angle range are used. It is a method of reconstructing a tomographic image of a subject from image information. Compared with computed tomography (abbreviated as CT), the imaging range and the number of tomography are limited, but since tomographic images can be obtained with a small X-ray dose, the digital processing technology for image information is rapidly advancing, It is expected to be applied in various fields including medical applications.
  • CT computed tomography
  • Digital radiography (digital X-ray photography), which has been in full swing since the beginning of the 21st century, uses a flat panel image sensor in the X-ray photosensitive section, which used to rely on the film until then. It is to be taken out as a digital signal.
  • X-ray source which is a light source
  • a traditional hot cathode X-ray tube is used in which thermoelectrons from a filament are accelerated by a high voltage and collide with an anode to obtain X-rays from the braking energy.
  • one X-ray tube is moved in one direction on an arc or parallel straight line trajectory with respect to the image sensor, and the irradiated X-rays from this X-ray tube are transmitted to the object in the vicinity of the image sensor. Scanning against.
  • thermoelectrons Due to the nature of thermoelectrons, it is not possible to quickly switch the blinking of X-ray irradiation by a simple and inexpensive method, and it is physically necessary to arrange multiple hot cathode X-ray tubes that tend to be large due to exhaust heat treatment or high voltage introduction. Nor was it economically rational.
  • the irradiation X-rays can be blinked easily and reliably, and the need for exhaust heat treatment is reduced, so that the X-ray tube can be downsized. It is possible, and a method of arranging a plurality of them and sequentially lighting them becomes practical. This eliminates the need for a drive mechanism for moving one X-ray tube, eliminates deterioration of image quality due to mechanical drive, shortens imaging time, and simplifies the entire imaging apparatus.
  • the tomosynthesis device includes a plurality of cold cathode X-ray sources for irradiating a subject with X-rays, and the plurality of cold cathode X-ray sources are two-dimensionally arranged on a predetermined plane. ..
  • a method of driving a tomosynthesis device is a method of driving a tomosynthesis device in which a plurality of cold cathode X-ray sources for irradiating a subject with X-rays are two-dimensionally arranged on a predetermined plane. , A plurality of cold cathode X-ray sources are sequentially blinked.
  • FIG. 1A is a schematic perspective view showing a conventional tomosynthesis device (using a rotating mechanism) using a hot cathode X-ray tube.
  • FIG. 1B is a schematic perspective view showing a conventional tomosynthesis apparatus (using a parallel movement mechanism) using a hot cathode X-ray tube.
  • FIG. 1C is a schematic diagram for explaining an imaging method of a conventional tomosynthesis apparatus using a hot cathode X-ray tube.
  • FIG. 2A is a schematic diagram showing a tomosynthesis device (small X-ray tubes arranged in an arc shape) using a plurality of small cold cathode X-ray sources.
  • FIG. 1A is a schematic perspective view showing a conventional tomosynthesis device (using a rotating mechanism) using a hot cathode X-ray tube.
  • FIG. 1B is a schematic perspective view showing a conventional tomosynthesis apparatus (using a parallel movement mechanism) using a hot cathode
  • FIG. 2B is a schematic diagram showing a tomosynthesis device using a plurality of small cold cathode X-ray sources (a plurality of X-ray sources arranged linearly in a single X-ray generator).
  • FIG. 3A is a schematic diagram showing a tomosynthesis device according to an example in which a plurality of small cold cathode X-ray sources are arranged in an arc shape.
  • FIG. 3B is a schematic diagram showing a tomosynthesis device according to an example in which a plurality of small cold cathode X-ray sources are two-dimensionally arranged on a predetermined plane.
  • FIG. 4A is a schematic diagram showing a tomosynthesis device according to an example in which some small cold cathode X-ray sources are arranged on different planes while avoiding obstacles.
  • FIG. 4B is a schematic diagram showing a tomosynthesis apparatus according to an example in which a plane on which a plurality of small-sized cold cathode X-ray sources is arranged has an inclination.
  • FIG. 5 is a schematic diagram for explaining an example of the blinking order of a plurality of small cold cathode X-ray sources.
  • FIG. 6 is a schematic diagram for explaining an example of blinking order and dose of a plurality of small cold cathode X-ray sources.
  • FIG. 7 is a schematic diagram for explaining an example of the blinking order and dose of a plurality of small cold cathode X-ray sources, and shows an example in which different anode voltages are applied in advance to specific X-ray sources.
  • a method of sequentially blinking driving of angled X-rays for tomosynthesis imaging can be considered. ..
  • a plurality of X-ray tubes or X-ray sources are arranged on an arc or a straight line in accordance with a conventional mechanical X-ray tube driving method, and they are sequentially blinked in a fixed direction. It is assumed that.
  • the arrangement of the cold cathode X-ray tube or the X-ray source which is small and can blink easily, is not limited to the conventional mechanically driven track, and the blinking order is free.
  • the present invention introduces a new usage and merit by introducing into the tomosynthesis the arrangement and blinking method of the cold cathode X-ray source that did not exist in the past.
  • a rotary mechanism drives the arcuate track, and a parallel mechanism drives the linear track.
  • the width of the arc (symbol A shown in FIG. 1A) and the length of the straight line (symbol B shown in FIG. 1B) are several tens cm to hundreds of tens of cm, and since there is also a drive mechanism, the tomosynthesis device itself is moved to take an image. I can't.
  • the tomosynthesis device is fixed, and an object to be photographed (affected part) is placed at a predetermined photographing place for photographing.
  • X-rays are emitted ten to several dozen times in the order from one end of the orbit to the other end (Fig. 1C). Since it is difficult for the hot cathode X-ray tube to quickly and reliably blink the thermoelectrons from the filament, the X-ray tube is kept irradiating X-rays while moving in orbit, and There was also a method of sequentially capturing only the image information from the position from one end of the trajectory to the other end, but with this, most of the X-ray dose does not contribute to imaging, and the object (affected part) becomes useless. You will be exposed. Therefore, at present, measures are taken to prevent the X-rays from being irradiated from the orbital positions other than the time of photographing by using a high-cost method such as blinking the anode voltage of the X-ray tube.
  • a high-cost method such as blinking the anode voltage of the X-ray tube.
  • each cold cathode X-ray tube or cold cathode source is arranged along an arc or straight line in the conventional tomosynthesis device.
  • the size of the X-ray source portion of the tomosynthesis device (reference A in FIG. 1A or reference B in FIG. 1B) does not change except that the X-ray tube drive mechanism is not required.
  • the blinking method of multiple cold cathode tubes or cold cathode sources is performed under the same condition from one end of the arc or linear array to the other end.
  • a plurality of X-ray irradiations from different angles with respect to the object (X-ray image sensor) necessary for tomosynthesis imaging are arranged one-dimensionally when viewed from the object (X-ray image sensor) ( 3A) is not necessary and may be realized by dispersing the cold cathode X-ray source in two dimensions (FIG. 3B). That is, a plurality of small cold cathode X-ray sources may be arranged two-dimensionally on a predetermined plane. As a result, the maximum length of the X-ray source portion can be reduced even if the same number of irradiations and the same intervals as those in the conventional arrangement are arranged (reference numeral C in FIG. 3A to reference numeral C in FIG.
  • a plurality of cold cathode X-ray sources are arranged so as to surround the object to be viewed when viewed from directly above the object.
  • the plurality of cold cathode sources arranged two-dimensionally when viewed from the object (X-ray image sensor) does not need to be equidistant from the object (X-ray image sensor), and different distances depending on the purpose. In addition, they may be dispersed in a three-dimensional space.
  • the X-ray source portion of the tomosynthesis device can be placed in the restricted space shape (FIG. 4A), and it can also be arranged so as to ensure imaging from a specific direction (FIG. 4B).
  • some small cold cathode X-ray sources are arranged on another plane closer to the object to be photographed, avoiding obstacles. Further, in the example shown in FIG.
  • the plane on which the plurality of small cold cathode X-ray sources are arranged has an inclination, and the small cold cathode X-ray source located at the center is directly above the object to be photographed. It is arranged.
  • the distances between the plurality of cold cathode X-ray sources and the object to be photographed are not the same, and at least two cold cathode X-ray sources are different from each other in the object to be photographed.
  • the blinking may be performed sequentially along the arrangement order of the plurality of cold cathode X-ray sources, or the blinking may be performed sequentially in an order different from the arrangement order of the plurality of cold cathode X-ray sources.
  • Fig. 5 it is not necessary that the blinking of the cold cathode X-ray source be performed once under the same conditions. If a higher X-ray dose is required for an image from irradiation from a particular direction, a large current can be set for irradiation in this direction. This can also be realized by repeating the irradiation (Fig. 6).
  • the X-ray dose of the cold cathode X-ray source G is 20 mAs
  • the X-ray dose of the other cold cathode X-ray sources G is 10 mAs.
  • the cold cathode X-ray source G may irradiate the X-ray dose of 20 mAs at a time, or may irradiate the X-ray dose of 10 mAs in two times. With a cold cathode X-ray source that does not mechanically move during imaging, the imaging time does not significantly increase even if the specific X-ray source is repeatedly irradiated. Such adjustment of the dose according to the irradiation direction is repeated in the same irradiation direction in order to correct a problem such as poor image quality found in the analysis of a certain image in addition to the case of being preset. The dose adjustment in the next irradiation direction can be performed dynamically in conjunction with image analysis by a computer.
  • the method of adjusting the irradiation conditions from each cold cathode X-ray source can affect not only the X-ray dose but also the X-ray energy, but the anode voltage of one X-ray tube is blinked or the energy level is changed. Up and down has already been done.
  • the anode voltage of each X-ray source is not dynamically adjusted, but different anode voltages are given to a specific X-ray source in advance, and the corresponding X-ray sources are provided.
  • By flashing the current of X it is possible to realize X-ray irradiation with different energies (FIG. 7).
  • FIG. 7 In the example shown in FIG.
  • the anode voltage is 40 keV in some cold cathode X-ray sources, while the anode voltage is 70 keV in the remaining cold cathode X-ray sources.
  • the combination of X-ray energy and its irradiation direction is uniquely determined, but the order and number of times can be arbitrarily selected.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

Le problème décrit par la présente invention est de fournir un dispositif compact de tomosynthèse qui met en œuvre une pluralité de sources de rayons X à cathode froide. La solution selon l'invention porte sur un dispositif de tomosynthèse comprenant une pluralité de sources de rayons X à cathode froide qui exposent un sujet à des rayons X, la pluralité des sources de rayons X à cathode froide étant disposée de façon bidimensionnelle sur un plan prédéterminé. Ledit procédé d'entraînement pour dispositif de tomosynthèse sert à un dispositif de tomosynthèse dans lequel une pluralité de sources de rayons X à cathode froide qui éclairent un sujet avec des rayons X sont disposées de façon bidimensionnelle sur un plan prédéterminé, et la pluralité des sources de rayons X à cathode froide sont amenées à clignoter à leur tour.
PCT/JP2020/002697 2019-01-29 2020-01-27 Dispositif de tomosynthèse et procédé pour l'entraîner WO2020158644A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962798325P 2019-01-29 2019-01-29
US62/798,325 2019-01-29

Publications (1)

Publication Number Publication Date
WO2020158644A1 true WO2020158644A1 (fr) 2020-08-06

Family

ID=71842244

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2020/002697 WO2020158644A1 (fr) 2019-01-29 2020-01-27 Dispositif de tomosynthèse et procédé pour l'entraîner

Country Status (1)

Country Link
WO (1) WO2020158644A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100034450A1 (en) * 2008-01-15 2010-02-11 Thomas Mertelmeier Method and device for producing a tomosynthetic 3d x-ray image
JP2011512004A (ja) * 2008-01-25 2011-04-14 テールズ 光電制御装置と組み合わせた少なくとも１つの電子源を備えるｘ線源
JP2013504365A (ja) * 2009-09-15 2013-02-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 分散型ｘ線源及びそれを有するｘ線イメージングシステム
US20160256128A1 (en) * 2014-02-26 2016-09-08 Carestream Health, Inc. Hybrid imaging apparatus and methods for interactive procedures
US20170311911A1 (en) * 2014-10-24 2017-11-02 Vatech Co., Ltd. X-ray generation apparatus for intra-oral x-ray imaging, guide holder, and intra-oral x-ray imaging system comprising same
US20180005796A1 (en) * 2016-05-16 2018-01-04 Nanox Imaging Plc X-ray tube and a controller thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100034450A1 (en) * 2008-01-15 2010-02-11 Thomas Mertelmeier Method and device for producing a tomosynthetic 3d x-ray image
JP2011512004A (ja) * 2008-01-25 2011-04-14 テールズ 光電制御装置と組み合わせた少なくとも１つの電子源を備えるｘ線源
JP2013504365A (ja) * 2009-09-15 2013-02-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 分散型ｘ線源及びそれを有するｘ線イメージングシステム
US20160256128A1 (en) * 2014-02-26 2016-09-08 Carestream Health, Inc. Hybrid imaging apparatus and methods for interactive procedures
US20170311911A1 (en) * 2014-10-24 2017-11-02 Vatech Co., Ltd. X-ray generation apparatus for intra-oral x-ray imaging, guide holder, and intra-oral x-ray imaging system comprising same
US20180005796A1 (en) * 2016-05-16 2018-01-04 Nanox Imaging Plc X-ray tube and a controller thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SPRENGER,F. ET AL.: "Distributed source x-ray tube technology for tomosynthesis imaging", PROCEEDINGS OF SPIE, vol. 7622, 23 March 2010 (2010-03-23), XP055361499, DOI: 10.1117/12.844586 *

Similar Documents

Publication Publication Date Title
US10405813B2 (en) Panoramic imaging using multi-spectral X-ray source
US6990175B2 (en) X-ray computed tomography apparatus
JP4864308B2 (ja) 増大した有効範囲を有するｘ線陽極
KR101875847B1 (ko) 방사선 촬영 장치 및 이를 이용한 방사선 촬영 방법
US8873716B2 (en) Method and system for controlling x-ray focal spot characteristics for tomosynthesis and mammography imaging
US9107642B2 (en) Method and apparatus for tomographic X-ray imaging and source configuration
WO2009115982A1 (fr) Dispositif de tomodensimétrie et procédé d'acquisition d'images par tomodensimétrie basés sur des microsources de rayons x réparties dans l'espace du type faisceau conique
US20150282774A1 (en) Stationary gantry computed tomography systems and methods with distributed x-ray source arrays
JP2010082428A (ja) Ｘ線コンピュータ断層撮影装置
US20110002442A1 (en) Circular tomosynthesis x-ray tube
JP2013504365A (ja) 分散型ｘ線源及びそれを有するｘ線イメージングシステム
JP2020048993A (ja) トモシンセシス撮影装置及びその作動方法
CN117241734A (zh) 带有运动补偿式多个脉冲x射线源的使用x射线柔性曲面板检测器的快速3d放射摄影
JP2004136021A (ja) 集中照射型放射線治療装置
WO2018174389A1 (fr) Appareil de radiographie et procédé de radiographie utilisant ledit appareil de radiographie
US20050163285A1 (en) X-ray CT apparatus
WO2020158644A1 (fr) Dispositif de tomosynthèse et procédé pour l'entraîner
JP7043381B2 (ja) トモシンセシス撮影装置及びその作動方法
JP2010284325A (ja) Ｘ線コンピュータ断層撮影装置
JP4208271B2 (ja) グリッド制御回転陽極型ｘ線管
WO2009027904A2 (fr) Système d'imagerie par rayons x avec un agencement cylindrique de source et de détecteur
JP5823178B2 (ja) Ｘ線ｃｔ装置
JP7007319B2 (ja) 放射線撮影装置、放射線撮影装置の作動方法、放射線撮影装置の作動プログラム
EP4224215A1 (fr) Procédés de correction de saturation et de configuration de gain dynamique
JP7175602B2 (ja) Ｘ線ｃｔ装置及びｘ線発生システム

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20748641

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 20748641

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: JP