WO2020141786A1 - Ensemble plateau de diagnostic - Google Patents

Ensemble plateau de diagnostic Download PDF

Info

Publication number
WO2020141786A1
WO2020141786A1 PCT/KR2019/018366 KR2019018366W WO2020141786A1 WO 2020141786 A1 WO2020141786 A1 WO 2020141786A1 KR 2019018366 W KR2019018366 W KR 2019018366W WO 2020141786 A1 WO2020141786 A1 WO 2020141786A1
Authority
WO
WIPO (PCT)
Prior art keywords
tray
diagnostic
tray assembly
present
trays
Prior art date
Application number
PCT/KR2019/018366
Other languages
English (en)
Korean (ko)
Inventor
김성욱
최상백
오재훈
Original Assignee
주식회사 엘지화학
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020190133081A external-priority patent/KR102135806B1/ko
Application filed by 주식회사 엘지화학 filed Critical 주식회사 엘지화학
Priority to CN201980085726.0A priority Critical patent/CN113226552A/zh
Publication of WO2020141786A1 publication Critical patent/WO2020141786A1/fr

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices

Definitions

  • the present invention relates to a diagnostic tray assembly, and more particularly, to a diagnostic tray assembly capable of receiving an allergen coated membrane.
  • Diagnostic chips for analyzing the components in a sample are usually produced by coating an antigen or the like on a membrane-shaped fixture. Thereafter, various biological information can be obtained by reacting the antigen coated on the prepared diagnostic chip with a sample to be analyzed.
  • the diagnostic chip In order to react the sample on the diagnostic chip, the diagnostic chip is mounted on a tray, and then mounted on an automated device that reacts with the sample. After the reaction with the sample is completed on the automated equipment, the tray equipped with the diagnostic chip is taken out again.
  • a method in which a plurality of trays are mounted in one mold and then the mold is mounted again in an automated equipment is used to mount multiple trays in an automated equipment for reaction with a sample.
  • the problem to be solved by the present invention is to shorten the process and time required for diagnosis for component analysis in a sample compared to the prior art.
  • Another problem to be solved by the present invention is to maximize the space utilization of the interior of the automated equipment where the reaction of the sample occurs compared to the prior art.
  • the first tray and the second tray are provided in parallel with each other is formed in a receiving portion that can be accommodated in the diagnostic membrane; And a connection portion provided between the first tray and the second tray, one end connected to the first tray, and the other end connected to the second tray.
  • the first tray and the second tray has a long bar shape having a predetermined width (W), a predetermined thickness (t) and a predetermined length (L), respectively, with the connecting portion between the The second tray is provided on the side of the first tray in the width (W) direction, and the connection part is provided with a diagnostic tray assembly made of ABS.
  • the ratio of the length L to the width W of the first tray and the second tray has a value of 10 to 30, and the length to the thickness t of the first tray and the second tray
  • the ratio of (L) may have a value of 20 to 40.
  • a notch having an indented shape may be formed in the connection portion so as to have a thickness thinner than that of other regions of the connection portion.
  • the notch portion may be formed at a central portion in the length (L) direction of the connection portion.
  • the notch portion may be formed at both ends in the length (L) direction of the connection portion.
  • the notch portion may be formed in a region spaced apart from the point where the connecting portion is connected to the first tray and the second tray in the center direction in the length (L) direction of the connecting portion.
  • the cross section of the notch portion may have a V-shape.
  • the cross section of the notch portion may have a U shape.
  • the notch portion may be formed only on the upper or lower surface of the connection portion.
  • the notch portion may be formed on upper and lower surfaces of the connection portion.
  • the notch portion formed on the lower surface of the connection portion may be formed at a position corresponding to the position of the notch portion formed on the upper surface of the connection portion.
  • the surface of the connecting portion may have a flat shape.
  • the diagnostic tray assembly may be an allergy diagnostic tray assembly.
  • FIG. 1 is a perspective view showing a state as viewed from above the diagnostic tray assembly according to the present invention.
  • Figure 2 is a perspective view showing a state viewed from the bottom of the diagnostic tray assembly according to the present invention.
  • FIG. 3 is a plan view showing the structure of a diagnostic tray assembly according to the present invention.
  • FIG. 4 is a cross-sectional view showing the structure of a diagnostic tray assembly cut in the A-A direction of FIG. 3.
  • FIG 5 is an enlarged view showing a first example of a connecting portion of the diagnostic tray assembly according to the first embodiment of the present invention.
  • FIG. 6 is an enlarged view showing a second example of the connection portion of the diagnostic tray assembly according to the first embodiment of the present invention.
  • FIG. 7 is an enlarged view showing a third example of the connecting portion of the diagnostic tray assembly according to the first embodiment of the present invention.
  • FIG 8 is an enlarged view showing a fourth example of the connection portion of the diagnostic tray assembly according to the first embodiment of the present invention.
  • FIG 9 is an enlarged view showing a first example of the connecting portion of the diagnostic tray assembly according to the second embodiment of the present invention.
  • FIG 10 is an enlarged view showing a second example of the connecting portion of the diagnostic tray assembly according to the second embodiment of the present invention.
  • FIG. 11 is an enlarged view showing a third example of the connecting portion of the diagnostic tray assembly according to the second embodiment of the present invention.
  • FIG. 12 is an enlarged view showing a fourth example of a connection portion of the diagnostic tray assembly according to the second embodiment of the present invention.
  • FIG. 13 is an enlarged view showing a first example of a connection portion of the diagnostic tray assembly according to the third embodiment of the present invention.
  • FIG. 14 is an enlarged view showing a second example of a connecting portion of the diagnostic tray assembly according to the third embodiment of the present invention.
  • FIG. 15 is an enlarged view showing a third example of the connecting portion of the diagnostic tray assembly according to the third embodiment of the present invention.
  • 16 is an enlarged view showing a fourth example of a connection portion of the diagnostic tray assembly according to the third embodiment of the present invention.
  • FIG. 1 is a perspective view showing a view of the diagnostic tray assembly according to the present invention as viewed from above
  • FIG. 2 is a perspective view showing a view of the diagnostic tray assembly according to the present invention as viewed from below.
  • 3 is a plan view showing the structure of a diagnostic tray assembly according to the present invention
  • FIG. 4 is a cross-sectional view showing the structure of a diagnostic tray assembly cut in the A-A direction of FIG. 3.
  • the diagnostic tray assembly 10 may include a plurality of trays including the first tray 100 and the second tray 200. 1 to 4 show a diagnostic tray assembly 10 consisting of 10 trays. However, the number of the diagnostic tray assembly 10 according to the present invention is not limited to the drawings, and may be composed of various numbers of trays.
  • the description of the specification of the first tray 100 and the second tray 200 may be equally applied to other trays constituting the diagnostic tray assembly 10 according to the present invention.
  • the first tray 100 and the second tray 200 may be provided in parallel in a state adjacent to each other.
  • FIG. 1 shows a state in which the first accommodating part 110 and the second accommodating part 210 are formed on the first tray 100 and the second tray 200, respectively.
  • a first protrusion 120 and a second protrusion 220 having a shape protruding downward may be formed on the first tray 100 and the second tray 200, respectively.
  • the upper portions of the first protrusion 120 and the second protrusion 220 have a structure indented downwards, so that each of the first protrusion 120 and the second protrusion 220 is inside. Spaces may be formed, and these spaces may be a first accommodating part 110 and a second accommodating part 210, respectively.
  • the diagnostic tray assembly 10 may further include a configuration of connecting a plurality of trays constituting the diagnostic tray assembly to each other. That is, the diagnostic tray assembly 10 may be provided between any two trays, and one end may be connected to one tray and the other end may be connected to the other tray to include a connection unit connecting the two trays to each other. 1 to 4, as an example, a connection part 300 provided between the first tray 100 and the second tray 200 is illustrated. That is, the diagnostic tray assembly 10 according to the present invention may have a structure in which a plurality of trays are provided in parallel with a predetermined interval spaced apart, and a connection part is provided between the plurality of trays to connect a plurality of trays to each other. Meanwhile, as illustrated in FIGS.
  • a plurality of trays including the first tray 100 and the second tray 200 may be connected in parallel in the width (W) direction of the trays by the connection unit 300. Therefore, the second tray 200 may be provided on the side in the width (W) direction of the first tray 100 with the connecting portion 300 interposed therebetween.
  • the trays are connected to each other by the connection unit, trays constituting the diagnostic tray assembly can be mounted at once in an automated device for sample reaction. Therefore, it is possible to significantly reduce the process and time compared to individually mounting the trays in an automated device for sample reaction. For example, when 10 trays are mounted on an automation device, according to the prior art, a process of mounting the 10 trays on one frame and then mounting the frame on the automation device is required. In the case of manufacturing a diagnostic tray assembly in which two trays are connected to each other by a connection part, the process and time required for the sample reaction in the automation device are significantly reduced because the diagnostic tray assembly needs to be mounted only once in the automation device.
  • the space occupied by the frame in the automation device disappears, so that utilization of the space inside the automation device can be maximized.
  • a plurality of trays of the tray assembly 10 may have an elongated bar shape.
  • the first tray 100 and the second tray 200 have a predetermined width W, a predetermined thickness t, and a predetermined length L. It can have an elongated rod shape. It can be interpreted that the first tray and the second tray have an elongated rod shape, and the first tray and the second tray have a length L that is considerably larger than the width W and the thickness t.
  • the ratio of the length L to the width W of the first tray 100 and the second tray 200 may have a value of 10 to 30, and the length L to the thickness t ) May also have a value of 20 to 40.
  • the plurality of trays constituting the tray assembly 10 according to the present invention may all have the same size and shape. Accordingly, the foregoing descriptions of the widths, thicknesses, and lengths of the first tray and the second tray can be applied to all trays constituting the tray assembly.
  • the present invention The connecting portion may be provided in plurality between two trays.
  • the connection part 300 provided between the first tray 100 and the second tray 200 may include the first tray 100 and the second tray 200.
  • a total of two may be provided, one in each of the upper region and the lower region.
  • a total of three connecting parts 300 may be provided, one for each of the upper area, the middle area, and the lower area of the first tray 100 and the second tray 200.
  • a notch portion 300a having an indented shape is formed in the connecting portion 300 of the diagnostic tray assembly 10 according to the present invention to have a thickness thinner than other regions of the connecting portion. Can.
  • the notch portion 300a having a relatively thin thickness in the connection portion 300 is more easily broken than other regions of the connection portion 300, some of the trays of the diagnostic tray assembly are used depending on the use state of the diagnostic tray assembly. It can be easily removed.
  • the notch portion 300a of the connection portion 300 may be formed at the central portion in the length (L) direction of the connection portion 300.
  • the notch portion 300a may be formed only on the upper or lower surface of the connecting portion 300 as shown in FIGS. 5 and 7, and the upper and lower surfaces of the connecting portion 300 as shown in FIGS. 6 and 8 It may be formed in all.
  • the notch portion 300a is formed only on the upper or lower surface of the connection portion 300, it is possible to easily cut the connection portion 300 as needed while maintaining the durability of the connection portion 300 as much as possible, and the notch portion 300a
  • cutting of the connecting portion 300 may be performed as quickly as possible.
  • the shape of the notch portion 300a according to the first embodiment of the present invention may have a V-shape as shown in FIGS. 5 to 6.
  • the notch part 300a has a V-shape
  • stress concentration occurs in the valley region of the'V-shape' where the shape of the notch part 300a changes rapidly, so that the notch part 300a needs to.
  • the connection part 300 can be cut as quickly as possible.
  • the shape of the notch portion 300a according to the first embodiment of the present invention may have a U-shape as shown in FIGS. 7 to 8.
  • the'U-shaped' should be interpreted as a concept including not only the lower end being formed as a curve, but also the lower end being formed at an angle as shown in FIGS. 7 and 8.
  • stress concentration in the notch portion 300a is relatively low or does not occur, thereby maintaining the durability of the connection portion 300 as much as possible.
  • the connection part 300 can be easily cut as necessary.
  • the notch portion 300a of the connection portion 300 may be formed at both ends in the length (L) direction of the connection portion 300. have. That is, according to the second embodiment of the present invention, the notch portion 300a of the connection portion 300 may be directly connected to the first tray 100 and the second tray 200. At this time, the notch portion 300a may be formed only on the upper or lower surface of the connecting portion 300 as shown in FIGS. 9 and 11, and the upper and lower surfaces of the connecting portion 300 as shown in FIGS. 10 and 12. It may be formed in all.
  • the first embodiment of the present invention Replace the above with an example.
  • the shape of the notch portion 300a according to the second embodiment of the present invention has a V-shape as shown in FIGS. 9 to 10 or a U-shape as shown in FIGS. 11 to 12. You may have When the notch portion 300a has a V-shape and a U-shape, the effects of the first notch 300a are also replaced with the above-described contents.
  • the notch portion 300a of the connection portion 300 has a connection portion 300 having a first tray 100 and a second tray 200 ) May be formed in a region spaced apart in a center direction in the length (L) direction of the connecting portion 300 from the point connected to.
  • the notch portion 300a may be formed only on the upper or lower surface of the connecting portion 300 as shown in FIGS. 13 and 15, and the upper and lower surfaces of the connecting portion 300 as shown in FIGS. 14 and 16. It may be formed in all.
  • the first embodiment of the present invention Replace the above with an example.
  • the shape of the notch portion 300a according to the third embodiment of the present invention also has a V-shape as shown in FIGS. 13 to 14 or a U-shape as shown in FIGS. 15 to 16. You may have When the notch portion 300a has a V-shape and a U-shape, the effects of the first notch 300a are also replaced with the above-described contents.
  • the connecting portion (as shown in FIGS. 6, 8, 10, 12, 14 and 16)
  • the notch formed on the lower surface of 300) may be formed at a position corresponding to the position of the notch formed on the upper surface of the connecting portion 300. In this case, the cutability of the connecting portion 300 at the notch portion may be maximized.
  • the surface of the connecting portion 300 according to the present invention may have a flat shape in which a notch portion is not formed.
  • connection part 300 may be made of a material having a rigidity sufficient to maintain the connection between the trays and a rigidity sufficient to be cut by a human force depending on the use state. .
  • connection part 300 when an impact is applied to one area of the connection part 300, plastic deformation is deformed more than a certain area in the one area so that the impact is not transmitted to other areas except the one area to which the impact is applied.
  • It can be made of a material having a degree of ductility and brittleness that can be broken after rising.
  • connection part 300 does not react even if it comes into contact with a sample provided in a diagnostic chip, and may be made of a material having biocompatibility that does not affect the diagnostic result of the sample.
  • connection part 300 may include one or more materials from the group consisting of polycarbonate, polyethylene, polypropylene and ABS. More preferably, the connecting portion 300 may be made of polycarbonate, polyethylene or polypropylene, or may be made of a mixture of polycarbonate and ABS. Meanwhile, the trays and the connecting portions of the diagnostic tray assembly according to the present invention may be made of the same material. When the trays and the connecting portions have the same material, efficiency in production of the tray assembly can be improved.
  • connection part 300 according to the present invention may be made of ABS material.
  • the ABS material has low ductility and high brittleness compared to polypropylene. Therefore, when the connection portion 300 is made of such an ABS material, since the connection portion 300 can be easily cut to suit the needs of the user, separation between trays can be easily performed.
  • the plurality of trays including the first tray and the second tray may each have an elongated rod shape, and the plurality of trays having an elongated rod shape may be connected to the ABS material.
  • the trays are connected in the width direction (see W, FIGS. 3 and 4) by 300, the ease of separation between trays according to a user's request may be significantly maximized.
  • a plurality of trays constituting the tray assembly are connected in parallel in the width direction of the trays (ie, one-dimensionally) by the connecting portion, so in order to separate the trays along the width direction of the trays It is only necessary to cut the formed connection. Accordingly, separation of the trays can be made much easier compared to the case where a plurality of trays are connected in parallel in the width direction as well as the thickness direction or the length direction (ie, two-dimensionally) of the trays.
  • the connecting portion connecting the trays is made of ABS material having low ductility and high brittleness, the user can break the connecting portion without exerting great force. Therefore, the separation of the trays can be made much easier compared to the case where the connecting portion is made of a material other than ABS.
  • a plurality of trays constituting the tray assembly each has an elongated bar shape, so that the user can easily break the connection in the state of holding the tray by hand. Therefore, the separation of the trays can be made much easier compared to the case where the trays are not elongated bar shapes, but have a rectangular parallelepiped shape in which the difference between width and thickness and length is not large.
  • connection part 300 according to the present invention may be made of the same material as the trays 100 and 200 constituting the tray assembly 10. In this case, the type and process of materials required to manufacture the tray assembly according to the present invention can be minimized.
  • connection part 300 may be made of different materials from the trays 100 and 200 constituting the tray assembly 10.
  • the connection part 300 since there is a boundary between the trays 100 and 200 and the connection part 300, when the person cuts the connection part 300 by applying a force to the connection part according to the use state, the trays 100 and 200 No shock is applied. Therefore, it is possible to solve the problem of damage to the trays 100 and 200 that may occur in the process of cutting the connecting portion 300.
  • the tray assembly for diagnosis according to the present invention may be a tray assembly for allergy diagnosis. That is, the present invention can be applied to the field of allergy diagnosis capable of diagnosing the presence or absence of an allergy by providing an allergen, such as an antigen, in a tray, that is, a membrane coated with allergen.
  • an allergen such as an antigen
  • the ratio of the length L to the width W of the first tray 100 and the second tray 200 may have a value of 10 to 30, with respect to the width W
  • the ratio of the length (L) is less than 10
  • the number of allergens coated on the membrane provided in the tray is limited, and thus, the high integration of the diagnostic tray may not be possible.
  • the ratio of the length (L) to the width (W) exceeds 30, the length of the tray becomes relatively long, which may cause problems in the quality of the tray.
  • problems such as bending of the tray without maintaining a straight shape may occur. Therefore, the ratio of the length (L) to the width (W) of the first tray (100) and the second tray (200) having a value of 10 to 30 is not a simple option, but a critical significance. can see.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'invention concerne un ensemble plateau de diagnostic. Selon un aspect de la présente invention, l'invention concerne un ensemble plateau de diagnostic comprenant : un premier plateau et un second plateau qui ont respectivement des parties de réception aptes à recevoir des membranes de diagnostic et qui sont disposées en parallèle les unes avec les autres; et une partie de liaison qui est disposée entre le premier plateau et le second plateau et dont une partie d'extrémité est reliée au premier plateau et l'autre partie d'extrémité est reliée au second plateau.
PCT/KR2019/018366 2019-01-03 2019-12-24 Ensemble plateau de diagnostic WO2020141786A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201980085726.0A CN113226552A (zh) 2019-01-03 2019-12-24 诊断托盘组件

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2019-0000843 2019-01-03
KR20190000843 2019-01-03
KR10-2019-0133081 2019-10-24
KR1020190133081A KR102135806B1 (ko) 2019-01-03 2019-10-24 진단용 트레이 조립체

Publications (1)

Publication Number Publication Date
WO2020141786A1 true WO2020141786A1 (fr) 2020-07-09

Family

ID=71406549

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2019/018366 WO2020141786A1 (fr) 2019-01-03 2019-12-24 Ensemble plateau de diagnostic

Country Status (1)

Country Link
WO (1) WO2020141786A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070056873A1 (en) * 2004-04-30 2007-03-15 Elorz Oscar L Blistered rapid diagnostic test with incorporated moisture absorbent material
KR20070054293A (ko) * 2005-11-23 2007-05-29 최세묵 체액 샘플 진단 키트
KR20080077383A (ko) * 2005-12-08 2008-08-22 코리스 바이오컨셉 신속 진단용 검사 장치
KR20150112913A (ko) * 2015-09-17 2015-10-07 (주)프로테옴텍 다중 진단용 병렬식 라인형 바이오칩
JP2016088597A (ja) * 2014-11-07 2016-05-23 三友機器株式会社 包装体用多層シート

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070056873A1 (en) * 2004-04-30 2007-03-15 Elorz Oscar L Blistered rapid diagnostic test with incorporated moisture absorbent material
KR20070054293A (ko) * 2005-11-23 2007-05-29 최세묵 체액 샘플 진단 키트
KR20080077383A (ko) * 2005-12-08 2008-08-22 코리스 바이오컨셉 신속 진단용 검사 장치
JP2016088597A (ja) * 2014-11-07 2016-05-23 三友機器株式会社 包装体用多層シート
KR20150112913A (ko) * 2015-09-17 2015-10-07 (주)프로테옴텍 다중 진단용 병렬식 라인형 바이오칩

Similar Documents

Publication Publication Date Title
JP2909601B2 (ja) キュベット・トレイ装置
WO2020130399A1 (fr) Appareil de gabarit de pression permettant d'amener un fil d'électrode en contact étroit avec une barre omnibus, et système de fabrication de module de batterie comprenant ledit appareil
WO2019209072A1 (fr) Support de tubes à échantillons
WO2018117549A1 (fr) Bandelette de mesure de lipides sanguins
WO2012128459A2 (fr) Cassette de plaquettes solaires
WO2017164493A1 (fr) Unité de pochoir d'impression
WO2022030922A1 (fr) Module de batterie ayant une structure capable d'absorber le gonflement d'élément, et bloc-batterie et véhicule le comprenant
WO2020141786A1 (fr) Ensemble plateau de diagnostic
WO2022065880A1 (fr) Plateau de kits de diagnostic
US20210018711A1 (en) Fiber optic cassettes and splice modules
WO2020004780A1 (fr) Appareil de montage à pression automatique destiné à presser un fil d'électrode contre une barre omnibus
WO2003072249A2 (fr) Systeme pour preparer et manipuler des sondes multiples d'ionisation-desorption laser
WO2010140763A2 (fr) Capteur biologique
WO2015008927A1 (fr) Puce de biocapteur
WO2024058341A1 (fr) Plateau coulissant et procédé de fabrication de plateau coulissant
WO2017061651A1 (fr) Broche de contact pour le test d'une borne électrique
KR102135806B1 (ko) 진단용 트레이 조립체
WO2017135579A1 (fr) Appareil d'éjection de bandelette destiné à un lecteur de glycémie
WO2022173267A1 (fr) Bande pour biocapteur, son procédé de fabrication, et dispositif de collecte et de mesure de sang l'utilisant
JP2001349825A (ja) キュベット・スタンド及びキュベット付きスタンド
CA2441439A1 (fr) Dispositif de reception pour porte-objets
WO2018052176A1 (fr) Multi-unité pour effectuer un test biochimique et test de réponse immunitaire, et méthode de test l'utilisant
WO2019194400A1 (fr) Structure de membrane pour la séparation de biomolécules
WO2024147571A1 (fr) Ensemble berceau et ensemble dispositif de diagnostic in vitro le comprenant
WO2020141826A1 (fr) Bloc de contacteurs d'une carte sonde verticale à auto-alignement et procédé de fabrication correspondant

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19907574

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 19907574

Country of ref document: EP

Kind code of ref document: A1