WO2020107213A1

WO2020107213A1 - Traditional chinese medicine composition, preparation process therefor, and application thereof

Info

Publication number: WO2020107213A1
Application number: PCT/CN2018/117691
Authority: WO
Inventors: 刘志杰
Original assignee: 深圳市得道健康管理有限公司; 刘志杰
Priority date: 2018-11-27
Filing date: 2018-11-27
Publication date: 2020-06-04
Also published as: CN111601611A

Abstract

A traditional Chinese medicine composition, consisting of the following parts by weight: 1-2 parts of Coptidis Rhizoma, 1-3 parts of Scutellariae Radix, 1-3 parts of Phellodendri Chinensis Cortex, 1-3 parts of Gardeniae Fructus, 1-3 parts of Rhei Radix et Rhizoma, 1-5 parts of Rhapontici Radix, 1-3 parts of Borneolum Syntheticum, 1-2 parts of Natrii Sulfas, 1-3 parts of Bletillae Rhizoma and 18-135 parts of adjuvants. The raw materials in the composition are coordinated with one another to achieve the effects of reducing inner heat, expelling toxins, and relieving swelling and pain, and are used to cure heat toxins, sores and ulcers, skin tinea and eczema, scalds, burns, and the like. The traditional Chinese medicine composition is prepared by an easy preparation process, can be prepared at room temperature and under atmospheric pressure, has high production efficiency, and is suitable for industrial production.

Description

Chinese medicine composition and its preparation process and application

Technical field

The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition capable of treating heat, heat, detoxification, swelling and analgesia, and its preparation process and application.

Background technique

In the sweltering hot summer, the persistent high temperature and sultry weather can easily accumulate heat and poison in the human body, and suffer long-term damp and hot attacks, which will make the skin appear red, swollen, hot and other uncomfortable symptoms. In the field of traditional Chinese medicine, heat poison is also known as warm poison, and it is generally caused by the stagnation of fiery disease. It is a general term for acute fever such as boils, erysipelas, and heat boils. When it invades the human body, it will destroy the physiological function of the human body and cause local gas. Blood stagnation, inconsistency between the health and the health, obstruction of the meridians, swelling and pain symptoms, which can easily lead to boils and carbuncles. The clinical manifestations are thermal ulcers (such as paronychia) and ulcers, boils, boils, skin on the body surface. Eczema and other skin diseases are the most common types of diseases in traditional Chinese medicine surgical diseases. They have the characteristics of rapid onset and some serious conditions. They can easily cause serious consequences of injury to the hands and feet. When the sores, poisons, and evils are in full bloom, they can also destroy the body's defense function. Through the conduction of the meridians, they can also affect or invade the internal organs, causing a series of internal pathological reactions. In some cases, fever, thirst, constipation, and Chi Chi embolism; in others, nausea and vomiting, irritability, dizziness, cough, bloody sputum embolism, or even life-threatening. At present, there is no effective Chinese medicine preparation for sores caused by heat toxicity.

Summary of the invention

For this reason, the technical problem to be solved by the present invention is how to provide a Chinese medicine composition that can effectively relieve the symptoms described in the background art, and its preparation process and application.

To solve the above technical problems, the technical solutions of the present invention are:

The invention provides a traditional Chinese medicine composition, which is composed of 1-2 parts of Coptis chinensis, 1-3 parts of Scutellaria baicalensis, 1-3 parts of Phellodendron, 1-3 parts of Gardenia, 1-3 parts of rhubarb in parts by weight , 1-5 parts leaked reeds, 1-3 parts borneol, 1-2 parts Glauber's salt, 1-3 parts Bletilla striata and 18-135 parts of auxiliary materials.

Preferably, the Chinese medicine composition is composed of 1.2-1.4 parts of Coptis chinensis, 1.2-1.4 parts of Scutellaria baicalensis, 1.2-1.3 parts of Phellodendron, 1.2-1.4 parts of Gardenia, 1.2-1.4 parts of rhubarb, 2-3 parts of Lulu, 1.2-1.4 It consists of borneol, 1.2-1.3 parts of thenardite, 1.2-1.4 parts of Bletilla striata, and 30-50 parts of auxiliary materials.

Preferably, the Chinese medicine composition is composed of 1.8-1.9 parts of Coptis chinensis, 2.2-2.8 parts of Scutellaria baicalensis, 2.2-2.8 parts of Phellodendron, 2.3-2.8 parts of Gardenia, 2.4-2.9 parts of rhubarb, 4-4.8 parts of Lulu, 2.2-2.8 It consists of borneol, 1.7-1.9 parts of thenardite, 2.2-2.7 parts of Bletilla striata, and 100-120 parts of auxiliary materials.

Preferably, the Chinese medicine composition consists of 1.5-1.7 parts of Coptis chinensis, 1.6-2 parts of Scutellaria baicalensis, 1.5-2 parts of Phellodendron, 1.5-2 parts of Gardenia, 1.6-2.2 parts of rhubarb, 3.2-3.8 parts of Lulu, 1.5-2 It consists of borneol, 1.4-1.6 parts of thenardite, 1.5-2 parts of Bletilla striata, and 70-90 parts of auxiliary materials.

Preferably, the composition consists of 1.5 parts of Coptis chinensis, 2 parts of Scutellaria baicalensis, 2 parts of Phellodendron, 2 parts of Gardenia, 1.5 parts of rhubarb, 3 parts of Lulu, 2 parts of borneol, 1.5 parts of Glauber's salt, and 2 parts of Bletilla striata. And 40 parts of accessories.

Preferably, the auxiliary material is sesame oil or honey.

The invention also provides a process for preparing the traditional Chinese medicine composition, which comprises the following steps:

S1, Weighing Coptis chinensis, Radix Scutellariae, Phellodendron, Gardenia, Rhubarb, Leu Lu, Glauber's Salt, and Baiji in proportion, and grinding to obtain a powdery mixture;

S2. Mix the powder mixture with borneol uniformly;

S3. Add auxiliary materials and mix evenly.

Preferably, the particle size of the powder mixture obtained in step S1 is 10-15 μm.

The invention also provides an application of the traditional Chinese medicine composition in the preparation of medicines for treating heat poisoning sores, skin eczema, water and fire scalds.

Compared with the prior art, the above technical solution of the present invention has the following advantages:

(1) The traditional Chinese medicine composition according to the present invention is composed of 1-2 parts of Coptis chinensis, 1-3 parts of Scutellaria baicalensis, 1-3 parts of Phellodendron, 1-3 parts of gardenia, 1- It consists of 3 parts of rhubarb, 1-5 parts of reed, 1-3 parts of borneol, 1-2 parts of thenardite, 1-3 parts of striata, and 18-135 parts of auxiliary materials. The composition is coordinated with each other according to the compatibility relationship of "Jun, Chen, Zuo, Shi", with proper compatibility and synergistic effect, which can clear away heat and detoxify, reduce swelling and relieve pain, and can be used to treat various heat and ulcer sores Not ulcerated (such as paronychia), can also be used for skin eczema, water and fire burns. Among the components used in the composition, Coptis chinensis, Leulu and Glauber's salt are the main medicines for clearing away heat and detoxification, reducing swelling and removing carbuncle, which is a medicine with significant efficacy for curing thermal skin diseases and surgical burns and scalds, abandoning the traditional The borax in the formula solves the problem that borax is not suitable for treating skin diseases, thereby obtaining a traditional Chinese medicine composition that can significantly alleviate skin diseases caused by heat toxicity.

(2) The process for preparing the traditional Chinese medicine composition according to the present invention includes the following steps: S1. Weighing Coptis chinensis, Radix Scutellariae, Phellodendron, Gardenia, Rhubarb, Leu Lu, Glauber's Salt, and Bletilla striata, and grinding to obtain a powder Mixture; S2, mix the powder mixture with borneol uniformly; S3, add auxiliary materials and mix evenly. The preparation process steps are simple, can be completed under normal temperature and pressure, the conditions are mild, the preparation efficiency is high, and it is suitable for industrial mass production.

BRIEF DESCRIPTION

In order to make the content of the present invention easier to understand clearly, the present invention will be further described in detail based on specific embodiments of the present invention and the accompanying drawings, in which

FIG. 1 is a process flow diagram of preparing the traditional Chinese medicine composition according to an embodiment of the present invention.

detailed description

Example 1

This embodiment provides a traditional Chinese medicine composition, which has the effects of clearing away heat and detoxifying, reducing swelling and relieving pain, and can be used to treat various types of heat ulcers, whether it has been ulcerated or not, such as paronychia; it can also be used Skin eczema, water and fire burns, etc.

The traditional Chinese medicine composition is composed of 1g of Coptis chinensis, 1g of Scutellaria baicalensis, 1g of Phellodendron amurense, 1g of gardenia, 1g of rhubarb, 1g of gourd, 1g of borneol, 1g of Glauber's salt, 1g of Bletilla striata, and 18g of auxiliary materials, which can be sesame oil or honey Since honey is not suitable for wound ulcers, the auxiliary material in this embodiment is preferably sesame oil.

This embodiment also provides a process for preparing the Chinese medicine composition, as shown in FIG. 1, which includes the following steps:

S1. Weighing Coptis chinensis, Scutellaria baicalensis, Phellodendron amurense, Gardenia, Rhubarb, Leulu, Glauber's salt, and Bletilla striata according to the above ratio, grinding and mixing the above substances to obtain a powdery mixture, and the particle size of the powdery mixture is 10 μm.

S2. Mix the powder mixture with borneol uniformly.

S3. Add sesame oil and mix well to obtain a paste composition.

In the above composition, Coptidis Rhizoma Coptidis has the effects of clearing away heat and dampness, purging fire and detoxifying, and can be used for treating dampness and heat, fullness of vomiting, vomiting and swallowing acid, diarrhea, jaundice, hyperpyrexia, hyperactivity of heart and fire, blood and heat, epidemic, Symptoms such as toothache, thirst, carbuncle and swollen boils, can also be used to treat eczema and eczema; Scutellaria has the effects of clearing away heat and dampness, purging fire, detoxifying and hemostasis. It can be used to treat dampness, nausea, chest tightness and nausea, dampness and heat , Diarrhea, jaundice, lung fever cough, hyperthermia, thirst, carbuncle and sore poison; Phellodendron has the effect of clearing away heat and dampness, purging fire and detoxifying, used to treat wet poisoning ulcers, eczema, aphthous boils, scalds, etc.; Gardenia It has the effects of purging fire, removing heat and dampness, cooling blood and detoxifying, swelling and analgesic for external use. It is used to treat fever, upset, jaundice with dampness and heat, astringent pain in shower syndrome, redness and pain in the eyes, and fire ulcers; rhubarb has diarrhea The effects of attacking accumulation, clearing away heat and purging fire, cooling blood and detoxification, removing blood stasis and clearing menstrual flow, removing dampness and yellowing can be used for real heat accumulation constipation, blood heat spitting blemishes, red eye pharyngeal swelling, carbuncle swollen boils, intestinal carbuncle abdominal pain, Blood stasis and amenorrhea, bruises, dysentery and heat dysentery, jaundice and urinary red, external treatment of burns and scalds; Leulu has the effect of clearing away heat and detoxification, eliminating carbuncle, used for the treatment of skin heat and toxins, ulcers, gangrene and hemorrhoids; The effect of clearing away heat and dispersing poison, clearing away eyesight, treating fever, high fever, dizziness, stroke, phlegm, convulsions, hoodia, deafness, laryngitis, deafness, sores and swollen sores, carbuncle and hemorrhoids, red eyes, swelling, pain, and nebula Cover eyes; Glauber's salt has the effects of laxative laxative, moisturizing and softening, clearing fire and reducing swelling. It can treat solid heat accumulation and intestinal swollen pain; Bletilla striata has the effect of reducing swelling and muscles, and can treat sores, swelling and poison.

The traditional Chinese medicine composition can be used for preparing medicines for treating heat ulcers, skin eczema, water and fire scalds.

Example 2

The traditional Chinese medicine composition is composed of 2g of Coptis chinensis, 3g of Scutellaria baicalensis, 3g of Phellodendron amurense, 3g of gardenia, 3g of rhubarb, 5g of gourd, 3g of borneol, 2g of Glauber's salt, 3g of scutellaria and 135g of auxiliary materials. The auxiliary materials may be sesame oil or honey Since honey is not suitable for wound ulcers, the auxiliary material in this embodiment is preferably sesame oil.

S1, Weighing Coptis chinensis, Scutellaria baicalensis, Phellodendron amurense, Gardenia, Rhubarb, Leulu, Glauber's salt, and Bletilla striata according to the above ratio, grinding and mixing the above substances to obtain a powder mixture, and the particle size of the powder mixture is 15 μm.

S2. Mix the powder mixture with borneol uniformly.

S3. Add sesame oil and mix well to obtain a paste composition.

Example 3

The traditional Chinese medicine composition is composed of 1.5 g of Coptis chinensis, 2 g of Scutellaria baicalensis, 2 g of Phellodendron amurense, 2 g of gardenia, 1.5 g of rhubarb, 3 g of gourd, 2 g of borneol, 1.5 g of Glauber's salt, 2 g of Bletilla striata, and 40 g of auxiliary materials. The auxiliary materials may be sesame oil, or It may be honey. Since honey is not suitable for wound ulcers, the auxiliary material in this embodiment is preferably sesame oil.

S1, Weighing Coptis chinensis, Scutellaria baicalensis, Phellodendron amurense, Gardenia, Rhubarb, Leulu, Glauber's salt, and Bletilla striata according to the above ratio, grinding and mixing the above substances to obtain a powdery mixture, and the particle size of the powdery mixture is 12 μm.

S2. Mix the powder mixture with borneol uniformly.

S3. Add sesame oil and mix well to obtain a paste composition.

Example 4-12

Examples 4-12 provide the traditional Chinese medicine compositions in the ratios shown in Table 1, and the preparation process of the traditional Chinese medicine compositions in each ratio is the same as that in Examples 1-3.

Table 1

Experimental example

58 patients with small area scald from 2008 to 2018 were selected. Among 53 patients, 28 were male and 30 were female. The age distribution was between 6-50 years old. All patients suffered from small area scald caused by water and fire. , Clinical manifestations are red and swollen, or there are blisters.

Treatment method: Apply the traditional Chinese medicine composition of the present invention to the affected area, apply three times a day, the dosage is determined by the area of the affected area, and apply for 10 days.

Criteria for curative effect: cure: the symptoms and signs disappear completely; marked effect: most of the symptoms and signs disappear after treatment; ineffective: the symptoms and signs have not been alleviated or even aggravated.

Efficacy statistics: 58 patients treated with the combination of heat-clearing and dry-removing traditional Chinese medicine described in Example 1, 58 cases were cured, 0 cases were markedly effective, and 0 cases were ineffective, with an effective rate of 100%. Chinese medicine composition for detoxification, swelling and pain relief.

Obviously, the above examples are only examples for clear explanation, and are not limitations on the implementation. For those of ordinary skill in the art, other different forms of changes or changes can be made based on the above description. There is no need to exhaustively list all implementations. The obvious changes or changes derived from this are still within the protection scope created by the present invention.

Claims

A traditional Chinese medicine composition, characterized in that, based on parts by weight, the traditional Chinese medicine composition is composed of 1-2 parts of Coptis chinensis, 1-3 parts of Scutellaria baicalensis, 1-3 parts of cork, 1-3 parts of gardenia, 1-3 parts of gardenia It is composed of rhubarb, 1-5 parts of reed, 1-3 parts of borneol, 1-2 parts of Glauber's salt, 1-3 parts of Bletilla striata, and 18-135 parts of auxiliary materials.
The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises 1.2-1.4 parts of Coptis chinensis, 1.2-1.4 parts of Scutellaria baicalensis, 1.2-1.3 parts of Phellodendron amurense, 1.2-1.4 parts of gardenia, 1.2-1.4 parts It is composed of rhubarb, 2-3 parts of leaked reed, 1.2-1.4 parts of borneol, 1.2-1.3 parts of thenardite, 1.2-1.4 parts of Bletilla striata, and 30-50 parts of auxiliary materials.
The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises 1.8-1.9 parts of Coptis chinensis, 2.2-2.8 parts of Scutellaria baicalensis, 2.2-2.8 parts of Phellodendron amurense, 2.3-2.8 parts of gardenia, 2.4-2.9 parts It is composed of rhubarb, 4-4.8 parts of reed, 2.2-2.8 parts of borneol, 1.7-1.9 parts of thenardite, 2.2-2.7 parts of Bletilla striata, and 100-120 parts of auxiliary materials.
The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises 1.5-1.7 parts of Coptis chinensis, 1.6-2 parts of Scutellaria baicalensis, 1.5-2 parts of Phellodendron amurense, 1.5-2 parts of gardenia, 1.6-2.2 parts It is composed of rhubarb, 3.2-3.8 parts of reed, 1.5-2 parts of borneol, 1.4-1.6 parts of thenardite, 1.5-2 parts of Bletilla striata, and 70-90 parts of auxiliary materials.
The traditional Chinese medicine composition according to claim 1, characterized in that the composition consists of 1.5 parts of Coptis chinensis, 2 parts of Scutellaria baicalensis, 2 parts of Phellodendron, 2 parts of Gardenia, 1.5 parts of rhubarb, and 3 parts of Lulu , 2 parts borneol, 1.5 parts Glauber's salt, 2 parts Bletilla striata and 40 parts of auxiliary materials.
The traditional Chinese medicine composition according to any one of claims 1 to 5, wherein the auxiliary material is sesame oil or honey.
A process for preparing the Chinese medicine composition according to any one of claims 1-5, characterized in that it comprises the following steps:

S1, Weighing Coptis chinensis, Radix Scutellariae, Phellodendron, Gardenia, Rhubarb, Leu Lu, Glauber's Salt, and Baiji in proportion, and grinding to obtain a powdery mixture;

S2. Mix the powder mixture with borneol uniformly;

S3. Add auxiliary materials and mix evenly.
The preparation process of the traditional Chinese medicine composition according to claim 7, wherein the particle size of the powder mixture obtained in step S1 is 10-15 μm.
An application of the traditional Chinese medicine composition according to any one of claims 1 to 5 in the preparation of a medicine for treating heat ulcers, skin eczema, water and fire scalds.