WO2020038085A1 - 生化分析仪 - Google Patents

生化分析仪 Download PDF

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Publication number
WO2020038085A1
WO2020038085A1 PCT/CN2019/091418 CN2019091418W WO2020038085A1 WO 2020038085 A1 WO2020038085 A1 WO 2020038085A1 CN 2019091418 W CN2019091418 W CN 2019091418W WO 2020038085 A1 WO2020038085 A1 WO 2020038085A1
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WIPO (PCT)
Prior art keywords
card
execution
sample disc
biochemical analyzer
return spring
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PCT/CN2019/091418
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English (en)
French (fr)
Inventor
赵冯
张小三
张文俊
侯伟博
许德晨
景宏维
孙家振
张国秀
Original Assignee
基蛋生物科技股份有限公司
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Application filed by 基蛋生物科技股份有限公司 filed Critical 基蛋生物科技股份有限公司
Publication of WO2020038085A1 publication Critical patent/WO2020038085A1/zh

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system

Definitions

  • the present application relates to the technical field of medical automatic detection equipment, and in particular to a biochemical analyzer.
  • biochemical analyzers are commonly used in clinical medical institutions.
  • the instruments consist of sample trays, reagent racks, sample loading devices, reagent loading devices, reflection dials, colorimetric devices, mixing devices, clear systems, ISE systems, and operating system.
  • dry biochemical analyzers have developed rapidly due to their fast and convenient operation, such as Roche's ReflotronPlus dry biochemical analyzer and FUJIFILM's 4000ie automatic dry biochemical analyzer.
  • Such instruments use the dry chemical method. Simply add the sample to the solid-phase carrier dry reagent strip for subsequent measurements, eliminating the need for traditional tubing systems.
  • the dry reagent structure is generally divided into a diffusion layer, a filter layer, a reagent layer, a color development layer, and a support layer from the top to the bottom.
  • the purpose of this application is to provide a biochemical analyzer to alleviate the technical problems of low efficiency of dry biochemical detection in the prior art.
  • a biochemical analyzer provided in this application includes: a rotatable sample disc and a detection mechanism;
  • the sample disc is provided with a plurality of clamping positions for clamping reagent strips; and the detection mechanism is configured to detect the position of each detection position on the sample disc when the position is detected by the detection mechanism. Information on the reagent strip clipped on the card slot.
  • the biochemical analyzer further includes an anti-optocoupler, one end of which is disposed above the sample disc, and the other end of which is disposed below the sample disc.
  • the through-beam photocoupler is used to detect whether a reagent strip is stuck on the card position.
  • biochemical analyzer further includes a number grid photocoupler and an out-of-step detection photocoupler;
  • the digital grid photocoupler and the out-of-step detection photocoupler are both disposed at the bottom end of the sample disc.
  • the digital grid photocoupler detects a reagent strip on one of the card positions, the Information collected by a detection mechanism on a reagent strip on the card position;
  • the out-of-step detection photocoupler is used to check whether the sample disc is out of step.
  • the biochemical analyzer further includes a reset photocoupler.
  • the reset photocoupler is disposed on a bottom end of the sample disc near a side of the out-of-step detection photocoupler. The sample disc is reset.
  • biochemical analyzer further includes a plurality of card feeding mechanisms
  • a plurality of the card feeding mechanisms are arranged in a fan shape on one side of the sample disc, and an interval between two adjacent card feeding mechanisms is the same as an interval between two adjacent card positions.
  • the card feeding mechanism includes a first driving portion, a first guiding portion, a first executing portion, and a first transmitting portion;
  • the first execution portion is disposed on the first guide portion, the first driving portion and the first execution portion are connected through the first transmission portion, and the first driving portion drives the first execution portion
  • the portion is reciprocated along the extending direction of the first guide portion to push the reagent strip into the card position.
  • the first execution portion includes a first slider, a first return spring, and a first execution plate;
  • first slider is slidably disposed on the first guide portion, the other end of the first slider is provided with a first extension plate, and the first extension plate is disposed near the sample.
  • first extension plate is provided with a first through hole and a first card slot, and the first card slot is provided on a side near the center of the sample disk, and the first card
  • the groove is in communication with the first through hole, and first mounting holes are also provided on both sides of the first extension plate, the first mounting hole passes through the first through hole, and the bolt passes through the first mounting hole.
  • the first return spring is installed in the first through hole, and one end of the first return spring abuts a side wall of the first through hole, and the other end of the first return spring is provided Above the first card slot;
  • the first execution board is connected to the first return spring, and one side of the first execution board extends to an end away from the first slot and abuts the first extension board.
  • the first execution board An end remote from the first return spring is provided in an arc shape, and an end remote from the first execution plate is provided on a side remote from the center of the sample disc.
  • the first guide portion is a slide rail
  • an end of the first slider close to the slide rail is provided with a slide groove matching the slide rail
  • one side of the first slider is provided with A clamping plate that cooperates with the first transmission portion, the clamping plate is fixed on the first slider by bolts, and the first transmission portion is disposed between the clamping plate and the first slider .
  • the card ejection mechanism includes a second driving portion, a second guiding portion, a second executing portion, and a second transmission portion;
  • the second driving portion and the second guide portion are both provided at the bottom end of the sample disc, the second execution portion is provided on the second guide portion, and the second driving portion and the The second execution part is connected through the second transmission part, and the second driving part drives the second execution part to reciprocate along the extending direction of the second guide part, so that the reagent strip is withdrawn from the card position.
  • the second execution portion includes a second slider, a second return spring, and a second execution plate
  • One end of the second slider is slidably disposed on the second guide portion, the other end of the second slider is provided with a second extension plate, and the second extension plate is disposed near the sample.
  • One end of the center of the disc, the second extension plate is provided with a second through hole and a second card slot, and the second card slot is provided on a side of the second through hole away from the center of the sample disk.
  • the second slot is in communication with the second through hole, and two sides of the second extension plate are also provided with second mounting holes.
  • the second mounting hole passes through the second through hole and the bolt passes through.
  • the second return spring is installed in the second through hole through the second mounting hole, and one end of the second return spring is in contact with a side wall of the second through hole, and the second The other end of the return spring is disposed above the second card slot;
  • the second execution board is connected to the second return spring, and one side of the second execution board extends to an end away from the second card slot and abuts against the second extension board.
  • the second execution board An end remote from the second return spring is provided in an arc shape, and an end of the second execution plate in an arc shape is provided on a side near the center of the sample disc.
  • the biochemical analyzer further includes a positioning mechanism, the positioning mechanism is disposed at an end of the first guide portion away from the sample disc, and the positioning mechanism is electrically connected to the first driving portion;
  • a positioning plate is provided at an end of the first slider far from the center of the sample disc. When the positioning plate is used to cooperate with the positioning mechanism, the first driving unit stops working.
  • a biochemical analyzer provided by the present application includes a rotatable sample disc and a detection mechanism; the sample disc is provided with a plurality of clamping positions for clamping a reagent strip; the detection mechanism is used for When each card position on the sample disc is rotated to the position of the detection mechanism, the information of the reagent strip caught on the card position is detected.
  • a detection mechanism is provided above the sample disc, and the sample disc can be rotated. In this way, the reagent strip in the card position on the sample disc can be continuously detected, thereby improving the detection. s efficiency. To alleviate the technical problems of low efficiency of dry biochemical detection in the prior art.
  • FIG. 1 is a schematic structural diagram of a biochemical analyzer according to an embodiment of the present application.
  • FIG. 2 is a schematic structural diagram of a sample disc and a card feeding mechanism of a biochemical analyzer according to an embodiment of the present application
  • FIG. 3 is a schematic structural diagram of a card feeding mechanism of a biochemical analyzer according to an embodiment of the present application
  • FIG. 4 is a schematic structural diagram of a first execution unit on a card feeding mechanism of a biochemical analyzer according to an embodiment of the present application.
  • Icons 100-sample disc; 200-detection mechanism; 300-optocoupler; 400-number grid optocoupler; 500-out-of-step detection optocoupler; 600-reset optocoupler; 700-card feed mechanism; 800-positioning Mechanism; 110-position; 710-first drive; 720-first guide; 730-first execution; 740-first transmission; 731-first slider; 732-first return spring; 733 -The first execution board; 734-the first extension board; 735-the positioning board; 736-the snap-in board; 7340-the first card slot.
  • FIG. 1 is a schematic structural diagram of a biochemical analyzer provided in an embodiment of the present application
  • FIG. 2 is a schematic structural diagram of a sample disc and a card feeding mechanism of the biochemical analyzer provided in an embodiment of the present application.
  • a biochemical analyzer provided by the present application includes: a rotatable sample disc 100 and a detection mechanism 200;
  • the sample disc 100 is provided with a plurality of clamping positions 110 for clamping reagent strips; the detection mechanism 200 is configured to rotate each of the clamping positions 110 on the sample disc 100 to the detection mechanism 200. When it is in the position, the information of the reagent strip clamped on the card position 110 is detected.
  • the detection mechanism 200 is an optical path.
  • the number of card slots 110 may be 12, 16, or more. In this application, 16 card slots 110 are used, and the number of card slots 110 may be adjusted according to the specific use situation.
  • the biochemical analyzer also includes a workbench, and the sample disc 100 and the detection mechanism 200 are both disposed on the workbench.
  • a biochemical analyzer provided by the present application is provided with a detection mechanism 200 above the sample disc 100, and the sample disc 100 can be rotated, so that the detection can be continuously held on the sample disc 100 by 110 The reagent strip in the test is performed, thereby improving the detection efficiency. To alleviate the technical problems of low efficiency of dry biochemical detection in the prior art.
  • the biochemical analyzer further includes an anti-optical coupler 300, one end of which is disposed above the sample disc 100, The other end is disposed below the sample disc 100, and the anti-optocoupler 300 is used to detect whether a reagent strip is stuck on the card position 110.
  • the photocoupler 300 is fixedly installed.
  • the card position 110 passes through the photocoupler 300, and the photocoupler 300 can detect whether there is a reagent strip on the card position 110, and
  • the sample disc 100 is rotated, so that the card position 110 where the reagent strip is installed passes through the photocoupler 300, thereby detecting whether the reagent strip is successfully installed.
  • the biochemical analyzer further includes a number grid photocoupler 400 and a step-out detection photocoupler 500;
  • the digital grid photocoupler 400 and the out-of-step detection photocoupler 500 are both disposed at the bottom end of the sample disc 100.
  • the digital grid photocoupler 400 detects one of the reagents on the card position 110
  • the detection mechanism 200 collects information of a reagent strip on the card position 110;
  • the out-of-step detection photocoupler 500 is used to check whether the sample disc 100 is out of step.
  • the digital grid photocoupler 400 and the out-of-step detection photocoupler 500 are arranged on the same mounting base.
  • the digital grid photocoupler 400 and the detection mechanism 200 work synchronously.
  • the detection mechanism 200 detects one card position 110, and several photocouplers sense the same time as the detection mechanism 200 detects the photocoupler, thereby ensuring that the detection mechanism 200 can hold the card position on the sample disc 100. All 110 are tested to improve the accuracy of the overall device.
  • the out-of-step detection photocoupler 500 can detect the out-of-step condition of the sample disc 100 so as to facilitate subsequent adjustment of the driving mechanism that drives the sample disc 100.
  • the biochemical analyzer further includes a reset photocoupler 600, which is disposed at the bottom end of the sample disc 100 near the out-of-step detection photocoupler 500. On one side, the reset photocoupler 600 is used to reset the sample disc 100.
  • the reset photocoupler 600 can detect whether the sample disc 100 is reset accurately, so as to ensure the accuracy of the next work of the sample disc 100 and the detection mechanism 200.
  • the biochemical analyzer further includes a plurality of card feeding mechanisms 700;
  • a plurality of the card-feeding mechanisms 700 are fan-shapedly disposed on one side of the sample disc 100, and an interval between two adjacent card-feeding mechanisms 700 and an interval between two adjacent card slots 110 are fan-shaped. the same.
  • a plurality of card-feeding mechanisms 700 are arranged in a fan shape so that the card-feeding mechanism 700 and the sample disc 100 are adapted, and the distance between two adjacent card-feeding mechanisms 700 and the two adjacent cards The intervals of the bits 110 are the same, so that multiple card feeding mechanisms 700 can work at the same time, and the speed of installing the reagent strips into the card slots 110 is increased.
  • FIG. 3 is a schematic structural diagram of a card feeding mechanism of a biochemical analyzer according to an embodiment of the present application. As shown in FIG. 3, based on the above embodiment, further, the card feeding mechanism 700 includes a first driving portion 710, a first guiding portion 720, a first execution portion 730, and a first transmission portion 740;
  • the first driving portion 710 and the first guide portion 720 are both disposed at the bottom end of the sample disc 100, the first execution portion 730 is disposed on the first guide portion 720, and the first A driving portion 710 is connected to the first execution portion 730 through the first transmission portion 740, and the first driving portion 710 drives the first execution portion 730 to reciprocate in an extending direction of the first guide portion 720. To push the reagent strip into the card slot 110.
  • the first transmission portion 740 is a belt
  • the first driving portion 710 includes a driving wheel and a driven wheel. Both ends of the driving wheel and the driven wheel are respectively disposed at both ends of the first guide portion 720.
  • the belt is used to connect the driving wheel and the driven wheel.
  • the moving wheel is connected, and the belt is also connected to the first execution portion 730 to drive the first execution portion 730 to move along the first guide portion 720.
  • one end of the first guide portion 720 is close to the edge of the table, and the other end of the first guide portion 720 extends toward the intersection of the work table in the center of the sample disc 100.
  • the first execution portion 730 can be opposite to The first guide portion 720 moves, so that the first execution portion 730 can push the reagent strip into the card position 110.
  • FIG. 4 is a schematic structural diagram of a first execution unit on a card feeding mechanism of a biochemical analyzer according to an embodiment of the present application.
  • the first execution unit 730 includes a first slider 731, a first return spring 732, and a first execution plate 733;
  • first slider 731 is slidably disposed on the first guide portion 720, and the other end of the first slider 731 is provided with a first extension plate 734, and the first extension plate 734 is disposed at An end near the center of the sample disc 100.
  • the first extension plate 734 is provided with a first through hole and a first clamping groove 7340.
  • the first clamping groove 7340 is disposed near the sample disc 100.
  • the first slot 7340 communicates with the first through hole, and two sides of the first extension plate 734 are also provided with first mounting holes, and the first mounting holes pass through the first A through hole, a bolt passing through the first mounting hole to install the first return spring 732 in the first through hole, and one end of the first return spring 732 and a side of the first through hole The wall abuts, and the other end of the first return spring 732 is disposed above the first slot 7340;
  • the first execution plate 733 is connected to the first return spring 732, and a side of the first execution plate 733 extends toward an end away from the first card slot 7340 and abuts the first extension plate 734.
  • An end of the first execution plate 733 remote from the first return spring 732 is arc-shaped, and an end of the first execution plate 733 curved is disposed at a side far from the center of the sample disc 100.
  • the first return spring 732 is a torsion spring.
  • a first extension plate 734 is provided on the first slider 731.
  • the first extension plate 734 is provided with a first through hole and a first mounting hole.
  • the first execution plate 733 is connected to the first return spring 732.
  • the bolt passes through the first mounting hole and the first return spring 732, the first return spring 732 is installed in the first through hole, and one end of the first return spring 732 is disposed above the first slot 7340, so that the first There is a gap between the return spring and the first clamping groove 7340, and the other end is disposed on the inner wall near the first through hole.
  • the side of the first execution plate 733 extends to an end away from the first slot 7340 and abuts the first extension plate 734.
  • the first execution board 733 will push the reagent strip from the outside into the card position 110.
  • the first execution board 733 will rotate toward the end of the card under the force, so that the first execution board 733 Smooth exit, reset by first return spring 732 after exit
  • the first guide portion 720 is a slide rail, and an end of the first slider near the slide rail is provided with a slide groove that cooperates with the slide rail.
  • One side of a slider 731 is provided with a clamping plate 736 for cooperating with the first transmission portion 740.
  • the clamping plate 736 is fixed on the first slider 731 by bolts.
  • the first transmission portion 740 is provided. Between the latching plate 736 and the first slider 731.
  • the first guide portion 720 is a slide rail, and a slide groove is provided at the bottom end of the first slider 731, so that the first slider 731 can slide on the first guide portion 720, and the first slider 731 can slide on the first slider 731.
  • a clamping plate 736 is also provided on one side of the 731. The clamping plate 736 fixes the belt to the first slider 731 by bolts, so that the belt drives the first slider 731 to move.
  • the card ejection mechanism includes a second driving portion, a second guiding portion, a second execution portion, and a second transmission portion;
  • the second driving portion and the second guide portion are both provided at the bottom end of the sample disc, the second execution portion is provided on the second guide portion, and the second driving portion and the The second execution part is connected through the second transmission part, and the second driving part drives the second execution part to reciprocate along the extending direction of the second guide part, so that the reagent strip is withdrawn from the card position.
  • the structures of the second transmission portion and the second driving portion are the same as those of the first transmission portion and the first driving portion.
  • one end of the second guide portion is close to the edge of the table, and the other end of the second guide portion extends to the intersection of the work table in the center of the sample disc.
  • the second execution portion can be opposite to the second guide portion. Move so that the second execution part can eject the reagent strip from the card position 110.
  • the second execution unit includes a second slider, a second return spring, and a second execution board;
  • One end of the second slider is slidably disposed on the second guide portion, the other end of the second slider is provided with a second extension plate, and the second extension plate is disposed near the sample.
  • One end of the center of the disc, the second extension plate is provided with a second through hole and a second card slot, and the second card slot is provided on a side of the second through hole away from the center of the sample disk.
  • the second slot is in communication with the second through hole, and two sides of the second extension plate are also provided with second mounting holes.
  • the second mounting hole passes through the second through hole and the bolt passes through.
  • the second return spring is installed in the second through hole through the second mounting hole, and one end of the second return spring is in contact with a side wall of the second through hole, and the second The other end of the return spring is disposed above the second card slot;
  • the second execution board is connected to the second return spring, and one side of the second execution board extends to an end away from the second card slot and abuts against the second extension board.
  • the second execution board An end remote from the second return spring is provided in an arc shape, and an end of the second execution plate in an arc shape is provided on a side near the center of the sample disc 100.
  • a second extension plate is provided on the second slider.
  • the second extension plate is provided with a second through hole and a second installation hole.
  • the second execution plate is connected to the second return spring, and the bolt passes through the first extension plate.
  • Two mounting holes and a second return spring the second return spring is installed in the second through hole, and one end of the second return spring is disposed above the second card slot, so that the second return spring and the second card There is a gap between the grooves, and the other end is disposed on the inner wall near the second through hole. Since the arcuate end of the second execution board is disposed near the center of the sample disc 100, the side of the second execution board is away from the first side. One end of the two card slots extends and abuts the second extension plate.
  • the second execution plate moves to the end away from the sample disc 100, the second execution plate will cause the reagent strip to exit from the card position 110,
  • the second execution board enters the card position 110, the second execution board is rotated by the force to make the second execution board enter smoothly. After the entry, it is reset by the second reset spring.
  • a positioning mechanism 800 is provided at an end of the table near the first guide portion 720 away from the sample disc 100, and the positioning mechanism 800 and the first A driving part 710 is electrically connected;
  • a positioning plate 735 is provided at an end of the first slider 731 away from the center of the sample disc 100. When the positioning plate 735 is used to cooperate with the positioning mechanism 800, the first driving portion 710 stops working.
  • the positioning plate 735 is L-shaped
  • the positioning mechanism 800 is a positioning photocoupler
  • the positioning photocoupler is U-shaped.
  • a positioning mechanism 800 is further provided on the workbench.
  • the positioning mechanism 800 is a U-shaped positioning optocoupler.
  • a positioning plate 735 is provided on the first slider 731, and the positioning plate 735 is provided in an L-shape.

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Abstract

本申请涉及医疗自动化检测设备技术领域,尤其是涉及一种生化分析仪。所述生化分析仪包括:可转动的试样圆盘和检测机构;所述试样圆盘上设置有多个用于卡接试剂条的卡位;所述检测机构用于在所述试样圆盘上的每个卡位转动至检测机构所在位置时,检测该卡位上卡接的试剂条的信息。上述生化分析仪能够改善现有技术中存在的干式生化检测效率低下的技术问题。

Description

生化分析仪
本申请要求在2018年8月20日提交中国专利局、申请号为2018109506661、发明名称为“生化分析仪”一件中国专利申请的优先权,其全部内容通过引用结合在本申请中。
技术领域
本申请涉及医疗自动化检测设备技术领域,尤其是涉及一种生化分析仪。
背景技术
自从Technicon公司在1957年成功的生产了世界上第一台全自动生化分析仪后,各种型号和功能不同的全自动生化仪不断的涌现,为医院的临床生化检验的自动化迈出十分重要的一步。
目前,临床医疗机构普遍使用的是分立式生化仪,仪器由样品盘、试剂架、样品加样装置、试剂加样装置、反映转盘、比色装置、混匀装置、清晰系统、ISE系统及操作系统。近年来,干式生化仪由于操作快速便捷等特点得到了快速发展,如Roche的ReflotronPlus型干式生化仪,FUJIFILM的4000ie全自动干式生化分析仪,此类仪器采用干化学的方法,使用时只需将样品加到固相载体干试剂条上即可进行后续测定,无需传统的管路系统。干式试剂结构分从上倒下一般分为扩散层、过滤层、试剂层、显色层和支持层。
在临床实践中,一个患者往往需要做几个干式生化的检测,同时,要做检测的患者数量巨大,目前的做法是将样本逐个放到干式检测仪器上进行各项目检测,不仅人工操作成本较高,测试反应灵敏度也不如预期,往往花费更过的时间还需要进一步测试,严重影响了患者的诊断。
发明内容
本申请的目的在于提供生化分析仪,以缓解现有技术中存在的干式生化检测效率低下的技术问题。
本申请提供的一种生化分析仪,包括:可转动的试样圆盘和检测机构;
所述试样圆盘上设置有多个用于卡接试剂条的卡位;所述检测机构用于在所述试样圆盘上的每个卡位转动至检测机构所在位置时,检测该卡位上卡接的试剂条的信息。
进一步地,所述生化分析仪还包括有对射光耦,所述对射光耦的一端设置在所述试样圆盘上方,所述对射光耦的另一端设置在所述试样圆盘下方,所述对射光耦用于检测所述卡位上是否卡设有试剂条。
进一步地,所述生化分析仪还包括数格子光耦和失步检测光耦;
所述数格子光耦和所述失步检测光耦均设置在所述试样圆盘的底端,当所述数格子光耦检测到其中一个所述卡位上的试剂条时,所述检测机构采集到一个所述卡位上的试剂条的信息;
所述失步检测光耦用于对试样圆盘是否失步。
进一步地,所述生化分析仪还包括有复位光耦,所述复位光耦设置在试样圆盘的底端靠近所述失步检测光耦的一侧,所述复位光耦用于使所述试样圆盘复位。
进一步地,所述生化分析仪还包括多个进卡机构;
多个所述进卡机构呈扇形设置在所述试样圆盘的一侧,且相邻的两个所述进卡机构的间隔与相邻的两个所述卡位的间隔相同。
进一步地,所述进卡机构包括第一驱动部、第一导向部、第一执行部和第一传动部;
所述第一执行部设置在所述第一导向部上,所述第一驱动部与所述第一执行部通过所述第一传动部连接,所述第一驱动部带动所述第一执行部沿所述第一导向部的延伸方向往复运动,以将试剂条推送至所述卡位中。
进一步地,所述第一执行部包括第一滑块、第一复位弹簧和第一执行板;
所述第一滑块的一端可滑动地设置在所述第一导向部上,所述第一滑块的另一端设置有第一延伸板,所述第一延伸板设置在靠近所述试样圆盘中心的一端,所述第一延伸板上设置有第一通孔和第一卡槽,所述第一卡槽设置在靠近所述试样圆盘中心的一侧,所述第一卡槽和所述第一通孔连通,所述第一延伸板的两侧还设置有第一安装孔,所述第一安装孔穿过所述第一通孔,螺栓穿过所述第一安装孔将所述第一复位弹簧安装在所述第一通孔中,且所述第一复位弹簧的一端与所述第一通孔的侧壁抵接,所述第一复位弹簧的另一端设置在所述第一卡槽的上方;
所述第一执行板与所述第一复位弹簧连接,所述第一执行板的一侧向远离所述第一卡槽的一端延伸并与第一延伸板抵接,所述第一执行板远离所述第一复位弹簧的一端呈弧形设置,所述第一执行板呈弧形的一端设置在远离所述试样圆盘中心一侧。
进一步地,所述第一导向部为滑轨,所述第一滑块靠近所述滑轨的一端设置有与所述滑轨配合的滑槽,所述第一滑块的一侧设置有用于和所述第一传动部配合的卡接板,所述卡接板通过螺栓固定在第一滑块上,所述第一传动部设置在所述卡接板和所述第一滑块之间。
进一步地,所述退卡机构包括第二驱动部、第二导向部、第二执行部和第二传动部;
所述第二驱动部和所述第二导向部均设在所述试样圆盘底端,所述第二执行部设置在所述第二导向部上,所述第二驱动部与所述第二执行部通过所述第二传动部连接,所述第二驱动部带动所述第二执行部沿所述第二导向部的延伸方向往复运动,以使试剂条从所述卡位退出。
进一步地,所述第二执行部包括第二滑块、第二复位弹簧和第二执行板;
所述第二滑块的一端可滑动地设置在所述第二导向部上,所述第二滑块的另一端设置有第二延伸板,所述第二延伸板设置在靠近所述试样圆盘中心的一端,所述第二延伸板上设置有第二通孔和第二卡槽,所述第二卡槽设置在所述第二通孔远离所述试样圆盘中心的一侧,所述第二卡槽和所述第二通孔连通,所述第二延伸板的两侧还设置有第二安装孔,所述第二安装孔穿过所述第二通孔,螺栓穿过所述第二安装孔将所述第二复位弹簧安装在所述第二通孔中,且所述第二复位弹簧的一端与所述第二通孔的侧壁抵接,所述第二复位弹簧的另一端设置在所述第二卡槽的上方;
所述第二执行板与所述第二复位弹簧连接,所述第二执行板的一侧向远离所述第二卡槽的一端延伸并与第二延伸板抵接,所述第二执行板远离所述第二复位弹簧的一端呈弧形设置,所述第二执行板呈弧形的一端设置在靠近所述试样圆盘中心一侧。
进一步地,所述生化分析仪还包括有定位机构,所述定位机构设置在所述第一导向部远离所述试样圆盘的一端,所述定位机构与所述第一驱动部电连接;
所述第一滑块远离所述试样圆盘中心的一端设置有定位板,当所述定位板用于与所述定位机构配合,所述第一驱动部停止工作。
本申请提供的一种生化分析仪,包括可转动的试样圆盘和检测机构;所述试样圆盘上设置有多个用于卡接试剂条的卡位;所述检测机构用于在所述试样圆盘上的每个卡位转动至检测机构所在位置时,检测该卡位上卡接的试剂条的信息。采用上述的方案,在试样圆盘的上方设置有检测机构,并且试样圆盘能够转动,这样检测即可持续不断的对试样圆盘上卡位中的试剂条进行检测,从而提高检测的效率。以缓解现有技术中存在的干式生化检测效率低下的技术问题。
附图说明
为了更清楚地说明本申请具体实施方式或现有技术中的技术方案,下面将对具体实施方式或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图是本申请的一些实施方式,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。
图1为本申请实施例提供的生化分析仪的结构示意图;
图2为本申请实施例提供的生化分析仪试样圆盘及进卡机构的结构示意图;
图3为本申请实施例提供的生化分析仪进卡机构的结构示意图;
图4为本申请实施例提供的生化分析仪进卡机构上第一执行部的结构示意图。
图标:100-试样圆盘;200-检测机构;300-对射光耦;400-数格子光耦;500-失步检测光耦;600-复位光耦;700-进卡机构;800-定位机构;110-卡位;710-第一驱动部;720-第一导向部;730-第一执行部;740-第一传动部;731-第一滑块;732-第一复位弹簧;733-第一执行板;734-第一延伸板;735-定位板;736-卡接板;7340-第一卡槽。
具体实施方式
下面将结合附图对本申请的技术方案进行清楚、完整地描述,显然,所描述的实施例是本申请一部分实施例,而不是全部的实施例。基于本申请中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本申请保护的范围。
在本申请的描述中,需要说明的是,术语“中心”、“上”、“下”、“左”、“右”、“竖直”、“水平”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本申请和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本申请的限制。此外,术语“第一”、“第二”、“第三”仅用于描述目的,而不能理解为指示或暗示相对重要性。
在本申请的描述中,需要说明的是,除非另有明确的规定和限定,术语“安装”、“相连”、“连接”应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或一体地连接;可以是机械连接,也可以是电连接;可以是直接相连,也可以通过中间媒介间接相连,可以是两个元件内部的连通。对于本领域的普通技术人员而言,可以具体情况理解上述术语在本申请中的具体含义。
图1为本申请实施例提供的生化分析仪的结构示意图;图2为本申请实施例提供的生化分析仪试样圆盘及进卡机构的结构示意图。如图1和2所示,本申请提供的一种生化分析仪,包括:可转动的试样圆盘100和检测机构200;
所述试样圆盘100上设置有多个用于卡接试剂条的卡位110;所述检测机构200用于在所述试样圆盘100上的每个卡位110转动至检测机构200所在位置时,检测该卡位110上卡接的试剂条的信息。
其中,检测机构200为光路通道。
卡位110的数量可为12个、16个或者更多,本申请中卡位110采用16个,还 可根据具体的使用情况进行调整。
另外生化分析仪还包括工作台,试样圆盘100和检测机构200均设置在工作台上。
本申请提供的一种生化分析仪,在试样圆盘100的上方设置有检测机构200,并且试样圆盘100能够转动,这样检测即可持续不断的对试样圆盘100上卡位110中的试剂条进行检测,从而提高检测的效率。以缓解现有技术中存在的干式生化检测效率低下的技术问题。
在上述实施例的基础上,进一步地,所述生化分析仪还包括有对射光耦300,所述对射光耦300的一端设置在所述试样圆盘100上方,所述对射光耦300的另一端设置在所述试样圆盘100下方,所述对射光耦300用于检测所述卡位110上是否卡设有试剂条。
本实施例中,对射光耦300固定设置,在试样圆盘100转动时,卡位110经过对射光耦300,对射光耦300即可检测到卡位110上是否存在有试剂条,而且在每个卡位110安装试剂条时,试样圆盘100均会转动,以使安装试剂条的卡位110经过对射光耦300,从而检测试剂条是否安装成功。
在上述实施例的基础上,进一步地,所述生化分析仪还包括数格子光耦400和失步检测光耦500;
所述数格子光耦400和所述失步检测光耦500均设置在所述试样圆盘100的底端,当所述数格子光耦400检测到其中一个所述卡位110上的试剂条时,所述检测机构200采集到一个所述卡位110上的试剂条的信息;
所述失步检测光耦500用于对试样圆盘100是否失步。
本实施例中,数格子光耦400和失步检测光耦500设置在同一安装座上,数格子光耦400和检测机构200同步工作,当数格子光耦400检测的一个卡位110上有试剂条时,检测机构200对一个卡位110进行检测,而且数个光耦感应到和检测机构200检测到光耦的时间相同,进而保障检测机构200能够将试样圆盘100上的卡位110全部检测,以提高整体装置的精度。同时失步检测光耦500能够检测出试样圆盘100失步的情况,以便于后续对驱动试样圆盘100的驱动机构进行调整。
在上述实施例的基础上,进一步地,所述生化分析仪还包括有复位光耦600,所述复位光耦600设置在试样圆盘100的底端靠近所述失步检测光耦500的一侧,所述复位光耦600用于使所述试样圆盘100复位。
本实施例中,复位光耦600能够使检测到试样圆盘100是否复位精确,以保障试样圆盘100及检测机构200下一次工作的精确程度。
在上述实施例的基础上,进一步地,所述生化分析仪还包括多个进卡机构700;
多个所述进卡机构700呈扇形设置在所述试样圆盘100的一侧,且相邻的两个所 述进卡机构700的间隔与相邻的两个所述卡位110的间隔相同。
其中,进卡机构700为四个。
本实施例中,多个进卡机构700呈扇形排布,以使进卡机构700和试样圆盘100相适应,且相邻的两个进卡机构700的间距和相邻的两个卡位110的间隔相同,这样多个进卡机构700能够同时工作,提高试剂条安装到卡位110中的速度。
图3为本申请实施例提供的生化分析仪进卡机构的结构示意图。如图3所示,在上述实施例的基础上,进一步地,所述进卡机构700包括第一驱动部710、第一导向部720、第一执行部730和第一传动部740;
所述第一驱动部710和所述第一导向部720均设在所述试样圆盘100的底端,所述第一执行部730设置在所述第一导向部720上,所述第一驱动部710与所述第一执行部730通过所述第一传动部740连接,所述第一驱动部710带动所述第一执行部730沿所述第一导向部720的延伸方向往复运动,以将试剂条推送至所述卡位110中。
其中,第一传动部740为皮带,第一驱动部710包括主动轮和从动轮,主动轮和从动轮的两端分别设置在第一导向部720的两端,皮带用于将主动轮和从动轮连接,且皮带还和第一执行部730连接,带动第一执行部730沿第一导向部720移动。
本实施例中,第一导向部720的一端靠近工作台的边沿,第一导向部720的另一端向试样圆盘100的中心有工作的台的交叉处延伸,第一执行部730能够相对第一导向部720移动,这样第一执行部730即可将试剂条推送到卡位110中。
图4为本申请实施例提供的生化分析仪进卡机构上第一执行部的结构示意图。如图4所示,在上述实施例的基础上,进一步地,所述第一执行部730包括第一滑块731、第一复位弹簧732和第一执行板733;
所述第一滑块731的一端可滑动地设置在所述第一导向部720上,所述第一滑块731的另一端设置有第一延伸板734,所述第一延伸板734设置在靠近所述试样圆盘100中心的一端,所述第一延伸板734上设置有第一通孔和第一卡槽7340,所述第一卡槽7340设置在靠近所述试样圆盘100中心的一侧,所述第一卡槽7340和所述第一通孔连通,所述第一延伸板734的两侧还设置有第一安装孔,所述第一安装孔穿过所述第一通孔,螺栓穿过所述第一安装孔将所述第一复位弹簧732安装在所述第一通孔中,且所述第一复位弹簧732的一端与所述第一通孔的侧壁抵接,所述第一复位弹簧732的另一端设置在所述第一卡槽7340的上方;
所述第一执行板733与所述第一复位弹簧732连接,所述第一执行板733的一侧向远离所述第一卡槽7340的一端延伸并与第一延伸板734抵接,所述第一执行板733远离所述第一复位弹簧732的一端呈弧形设置,所述第一执行板733呈弧形的一端设置在远离所述试样圆盘100中心一侧。
其中,第一复位弹簧732为扭簧。
本实施例中,在第一滑块731上设置有一第一延伸板734,第一延伸板734上设有第一通孔及第一安装孔,第一执行板733与第一复位弹簧732连接,螺栓穿过第一安装孔及第一复位弹簧732,将第一复位弹簧732安装在第一通孔中,而且第一复位弹簧732的一端设置在第一卡槽7340的上方,这样,第一复位弹簧即会与第一卡槽7340之间存在间隙,另一端设置在靠近第一通孔的内壁上,由于第一执行板733呈弧形的一端设置在远离所述试样圆盘100中心一侧,第一执行板733一侧向远离第一卡槽7340的一端延伸并与第一延伸板734抵接,在第一执行板733向靠近试样圆盘100一端移动时,第一执行板733即会将试剂条从外侧推送至卡位110中,在第一执行板733退出时,第一执行板733受到作用力即会朝向卡擦的一端转动,以使第一执行板733顺利的退出,退出后通过第一复位弹簧732进行复位。
在上述实施例的基础上,进一步地,所述第一导向部720为滑轨,所述第一滑块靠近所述滑轨的一端设置有与所述滑轨配合的滑槽,所述第一滑块731的一侧设置有用于和所述第一传动部740配合的卡接板736,所述卡接板736通过螺栓固定在第一滑块731上,所述第一传动部740设置在所述卡接板736和所述第一滑块731之间。
本实施例中,第一导向部720为滑轨,第一滑块731的底端设置有滑槽,以使第一滑块731能够在第一导向部720上滑动,并且在第一滑块731的一侧还设置有卡接板736,卡接板736通过螺栓将皮带与第一滑块731固定,从而使皮带带动第一滑块731移动。
在上述实施例的基础上,进一步地,所述退卡机构包括第二驱动部、第二导向部、第二执行部和第二传动部;
所述第二驱动部和所述第二导向部均设在所述试样圆盘底端,所述第二执行部设置在所述第二导向部上,所述第二驱动部与所述第二执行部通过所述第二传动部连接,所述第二驱动部带动所述第二执行部沿所述第二导向部的延伸方向往复运动,以使试剂条从所述卡位退出。
其中,第二传动部和第二驱动部的结构与第一传动部和第一驱动部的结构相同。
本实施例中,第二导向部的一端靠近工作台的边沿,第二导向部的另一端向试样圆盘的中心有工作的台的交叉处延伸,第二执行部能够相对第二导向部移动,这样第二执行部能够使试剂条从卡位110退出中。
在上述实施例的基础上,进一步地,所述第二执行部包括第二滑块、第二复位弹簧和第二执行板;
所述第二滑块的一端可滑动地设置在所述第二导向部上,所述第二滑块的另一端设置有第二延伸板,所述第二延伸板设置在靠近所述试样圆盘中心的一端,所述第二延伸板上设置有第二通孔和第二卡槽,所述第二卡槽设置在所述第二通孔远离所述试 样圆盘中心的一侧,所述第二卡槽和所述第二通孔连通,所述第二延伸板的两侧还设置有第二安装孔,所述第二安装孔穿过所述第二通孔,螺栓穿过所述第二安装孔将所述第二复位弹簧安装在所述第二通孔中,且所述第二复位弹簧的一端与所述第二通孔的侧壁抵接,所述第二复位弹簧的另一端设置在所述第二卡槽的上方;
所述第二执行板与所述第二复位弹簧连接,所述第二执行板的一侧向远离所述第二卡槽的一端延伸并与第二延伸板抵接,所述第二执行板远离所述第二复位弹簧的一端呈弧形设置,所述第二执行板呈弧形的一端设置在靠近所述试样圆盘100中心一侧。
本实施例中,在第二滑块上设置有一第二延伸板,第二延伸板上设有第二通孔及第二安装孔,第二执行板与第二复位弹簧连接,螺栓穿过第二安装孔及第二复位弹簧,将第二复位弹簧安装在第二通孔中,而且第二复位弹簧的一端设置在第二卡槽的上方,这样,第二复位弹簧即会与第二卡槽之间存在间隙,另一端设置在靠近第二通孔的内壁上,由于第二执行板呈弧形的一端设置在靠近试样圆盘100中心一侧,第二执行板一侧向远离第二卡槽的一端延伸并与第二延伸板抵接,在第二执行板向远离试样圆盘100一端移动时,第二执行板即会使试剂条从卡位110中退出,在第二执行板进入卡位110中时,第二执行板受到作用力转动,以使第二执行板顺利的进入,进入后通过第二复位弹簧进行复位。
在上述实施例的基础上,进一步地,在所述工作台边沿靠近所述第一导向部720远离所述试样圆盘100的一端设置有定位机构800,所述定位机构800与所述第一驱动部710电连接;
所述第一滑块731远离所述试样圆盘100中心的一端设置有定位板735,当所述定位板735用于与所述定位机构800配合,所述第一驱动部710停止工作。
进一步地,所述定位板735呈L型设置,所述定位机构800为定位光耦,所述定位光耦呈U型设置。
本实施例中,在工作台上还设置有定位机构800,定位机构800为呈U型的定位光耦,在第一滑块731上设置有定位板735,定位板735呈L型设置,定位板735与定位光耦配合时,即为第一滑块731移动到预定的位置,此时第一驱动部710停止工作,以保障第一滑块731的位置相对稳定。
最后应说明的是:以上各实施例仅用以说明本申请的技术方案,而非对其限制;尽管参照前述各实施例对本申请进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分或者全部技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本申请各实施例技术方案的范围。

Claims (10)

  1. 一种生化分析仪,其特征在于,包括:可转动的试样圆盘和检测机构;
    所述试样圆盘上设置有多个用于卡接试剂条的卡位;所述检测机构用于在所述试样圆盘上的每个卡位转动至检测机构所在位置时,检测该卡位上卡接的试剂条的信息。
  2. 根据权利要求1所述的生化分析仪,其特征在于,所述生化分析仪还包括有对射光耦、数格子光耦和失步检测光耦;
    所述对射光耦的一端设置在所述试样圆盘上方,所述对射光耦的另一端设置在所述试样圆盘下方,所述对射光耦用于检测所述卡位上是否卡设有试剂条;
    所述数格子光耦和所述失步检测光耦均设置在所述试样圆盘的底端,当所述数格子光耦检测到其中一个所述卡位上的试剂条时,所述检测机构采集到一个所述卡位上的试剂条的信息;
    所述失步检测光耦用于对试样圆盘是否失步。
  3. 根据权利要求2所述的生化分析仪,其特征在于,所述生化分析仪还包括有复位光耦,所述复位光耦设置在试样圆盘的底端靠近所述失步检测光耦的一侧,所述复位光耦用于使所述试样圆盘复位。
  4. 根据权利要求3所述的生化分析仪,其特征在于,所述生化分析仪还包括多个进卡机构和一个退卡机构;
    多个所述进卡机构和一个退卡机构呈扇形设置在所述试样圆盘的一侧,且相邻的两个所述进卡机构的间隔与相邻的两个所述卡位的间隔相同。
  5. 根据权利要求4所述的生化分析仪,其特征在于,所述生化分析仪所述进卡机构包括第一驱动部、第一导向部、第一执行部和第一传动部;
    所述第一驱动部和所述第一导向部均设在所述试样圆盘底端,所述第一执行部设置在所述第一导向部上,所述第一驱动部与所述第一执行部通过所述第一传动部连接,所述第一驱动部带动所述第一执行部沿所述第一导向部的延伸方向往复运动,以将试剂条推送至所述卡位中。
  6. 根据权利要求5所述的生化分析仪,其特征在于,所述第一执行部包括第一滑块、第一复位弹簧和第一执行板;
    所述第一滑块的一端可滑动地设置在所述第一导向部上,所述第一滑块的另一端设置有第一延伸板,所述第一延伸板设置在靠近所述试样圆盘中心的一端,所述第一延伸板上设置有第一通孔和第一卡槽,所述第一卡槽设置在靠近所述试样圆盘中心的一侧,所述第一卡槽和所述第一通孔连通,所述第一延伸板的两侧 还设置有第一安装孔,所述第一安装孔穿过所述第一通孔,螺栓穿过所述第一安装孔将所述第一复位弹簧安装在所述第一通孔中,且所述第一复位弹簧的一端与所述第一通孔的侧壁抵接,所述第一复位弹簧的另一端设置在所述第一卡槽的上方;
    所述第一执行板与所述第一复位弹簧连接,所述第一执行板的一侧向远离所述第一卡槽的一端延伸并与第一延伸板抵接,所述第一执行板远离所述第一复位弹簧的一端呈弧形设置,所述第一执行板呈弧形的一端设置在远离所述试样圆盘中心一侧。
  7. 根据权利要求6所述的生化分析仪,其特征在于,所述第一导向部为滑轨,所述第一滑块靠近所述滑轨的一端设置有与所述滑轨配合的滑槽,所述第一滑块的一侧设置有用于和所述第一传动部配合的卡接板,所述卡接板通过螺栓固定在第一滑块上,所述第一传动部设置在所述卡接板和所述第一滑块之间。
  8. 根据权利要求7所述的生化分析仪,其特征在于,所述退卡机构包括第二驱动部、第二导向部、第二执行部和第二传动部;
    所述第二驱动部和所述第二导向部均设在所述试样圆盘底端,所述第二执行部设置在所述第二导向部上,所述第二驱动部与所述第二执行部通过所述第二传动部连接,所述第二驱动部带动所述第二执行部沿所述第二导向部的延伸方向往复运动,以使试剂条从所述卡位退出。
  9. 根据权利要求8所述的生化分析仪,其特征在于,所述第二执行部包括第二滑块、第二复位弹簧和第二执行板;
    所述第二滑块的一端可滑动地设置在所述第二导向部上,所述第二滑块的另一端设置有第二延伸板,所述第二延伸板设置在靠近所述试样圆盘中心的一端,所述第二延伸板上设置有第二通孔和第二卡槽,所述第二卡槽设置在所述第二通孔远离所述试样圆盘中心的一侧,所述第二卡槽和所述第二通孔连通,所述第二延伸板的两侧还设置有第二安装孔,所述第二安装孔穿过所述第二通孔,螺栓穿过所述第二安装孔将所述第二复位弹簧安装在所述第二通孔中,且所述第二复位弹簧的一端与所述第二通孔的侧壁抵接,所述第二复位弹簧的另一端设置在所述第二卡槽的上方;
    所述第二执行板与所述第二复位弹簧连接,所述第二执行板的一侧向远离所述第二卡槽的一端延伸并与第二延伸板抵接,所述第二执行板远离所述第二复位弹簧的一端呈弧形设置,所述第二执行板呈弧形的一端设置在靠近所述试样圆盘中心一侧。
  10. 根据权利要求9所述的生化分析仪,其特征在于,所述生化分析仪还包括有定位机构,所述定位机构设置在所述第一导向部远离所述试样圆盘的一端,所述定位机构与所述第一驱动部电连接;
    所述第一滑块远离所述试样圆盘中心的一端设置有定位板,当所述定位板用于与所述定位机构配合,所述第一驱动部停止工作。
PCT/CN2019/091418 2018-08-20 2019-06-14 生化分析仪 WO2020038085A1 (zh)

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