WO2019093555A1 - Suture tubulaire de type cône et ensemble aiguille l'incorporant - Google Patents

Suture tubulaire de type cône et ensemble aiguille l'incorporant Download PDF

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Publication number
WO2019093555A1
WO2019093555A1 PCT/KR2017/012819 KR2017012819W WO2019093555A1 WO 2019093555 A1 WO2019093555 A1 WO 2019093555A1 KR 2017012819 W KR2017012819 W KR 2017012819W WO 2019093555 A1 WO2019093555 A1 WO 2019093555A1
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WIPO (PCT)
Prior art keywords
suture
region
mesh
weaving
participating
Prior art date
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PCT/KR2017/012819
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English (en)
Korean (ko)
Inventor
이도경
이상억
박은지
Original Assignee
주식회사 파인수처스
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Publication of WO2019093555A1 publication Critical patent/WO2019093555A1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166Sutures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06066Needles, e.g. needle tip configurations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06At least partially resorbable materials
    • A61L17/10At least partially resorbable materials containing macromolecular materials
    • A61L17/12Homopolymers or copolymers of glycolic acid or lactic acid
    • DTEXTILES; PAPER
    • D02YARNS; MECHANICAL FINISHING OF YARNS OR ROPES; WARPING OR BEAMING
    • D02GCRIMPING OR CURLING FIBRES, FILAMENTS, THREADS, OR YARNS; YARNS OR THREADS
    • D02G3/00Yarns or threads, e.g. fancy yarns; Processes or apparatus for the production thereof, not otherwise provided for
    • D02G3/22Yarns or threads characterised by constructional features, e.g. blending, filament/fibre
    • D02G3/26Yarns or threads characterised by constructional features, e.g. blending, filament/fibre with characteristics dependent on the amount or direction of twist
    • DTEXTILES; PAPER
    • D02YARNS; MECHANICAL FINISHING OF YARNS OR ROPES; WARPING OR BEAMING
    • D02GCRIMPING OR CURLING FIBRES, FILAMENTS, THREADS, OR YARNS; YARNS OR THREADS
    • D02G3/00Yarns or threads, e.g. fancy yarns; Processes or apparatus for the production thereof, not otherwise provided for
    • D02G3/22Yarns or threads characterised by constructional features, e.g. blending, filament/fibre
    • D02G3/26Yarns or threads characterised by constructional features, e.g. blending, filament/fibre with characteristics dependent on the amount or direction of twist
    • D02G3/28Doubled, plied, or cabled threads
    • DTEXTILES; PAPER
    • D02YARNS; MECHANICAL FINISHING OF YARNS OR ROPES; WARPING OR BEAMING
    • D02GCRIMPING OR CURLING FIBRES, FILAMENTS, THREADS, OR YARNS; YARNS OR THREADS
    • D02G3/00Yarns or threads, e.g. fancy yarns; Processes or apparatus for the production thereof, not otherwise provided for
    • D02G3/44Yarns or threads characterised by the purpose for which they are designed
    • DTEXTILES; PAPER
    • D02YARNS; MECHANICAL FINISHING OF YARNS OR ROPES; WARPING OR BEAMING
    • D02GCRIMPING OR CURLING FIBRES, FILAMENTS, THREADS, OR YARNS; YARNS OR THREADS
    • D02G3/00Yarns or threads, e.g. fancy yarns; Processes or apparatus for the production thereof, not otherwise provided for
    • D02G3/44Yarns or threads characterised by the purpose for which they are designed
    • D02G3/448Yarns or threads for use in medical applications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00526Methods of manufacturing

Definitions

  • the present invention relates to a cone-type tubular suture and a needle assembly incorporating the tubular suture, and more particularly, to a tubular suture having a tubular suture having a mesh face while forming a hollow portion into which needle- The front end of the needle inserted into the hollow body is guided by the needle tube introduced into the hollow portion to form the cone type so that the suture thread is tightly formed at the front end portion of the suture thread to prevent the needle threading from being deviated to the side through the gap between the individual suture threads
  • the present invention relates to a cone-type tubular suture that can loosely form suture twist intervals in the middle portion of the suture and improve the tissue filling effect by facilitating the inflow of the regenerated human tissue into the inner hollow portion.
  • a suture used as a surgical suture material is a thread used to suture tissue damage due to surgical trauma and can be classified into a biodegradable suture and a non-biodegradable suture depending on the decomposition in vivo.
  • a biodegradable suture is a thread that spontaneously breaks down after a period of time after the damaged part of the tissue is sutured. It is mainly used to fix the skin or to suture the soft tissue.
  • a non biodegradable suture is a thread that is not degraded even after the damaged part of the tissue has been sealed, mainly used for blood vessels and orthopedic surgery.
  • sutures are used in a great number of applications such as lifting for pulling tissue by insertion of a human tissue, filler for restoring volume, and the like since the suture has good tightness with human tissue.
  • the human tissue includes a midnight healing material that surrounds the foreign material to protect the skin tissue from foreign matter when the foreign matter penetrates into the skin.
  • a self-healing substance protects the subcutaneous tissues and, as a result, provides the function of strengthening the muscles inside the subcutaneous layer. Therefore, by inserting the suture into the human body and fixing it, it can be used for preventing or restoring the sagging or depression of the skin by providing a tension between human tissues for a while.
  • Korean Unexamined Patent Publication No. 10-2014-0127333 (published on November 3, 2014; hereinafter referred to as "Prior Art 1”) presented improved sutures.
  • the suture is formed in a tubular shape, since the surgical needle is attached to the front end of the suture to be inserted into the human body, the needle is inserted before the needle into the human body to draw the suture. And then discharged.
  • US Patent No. 4372293 (registered on Feb. 2, 1983) refers to an apparatus and a method for surgical correction of a sagittal chest.
  • the tubular mesh is applied, but both ends of the tubular mesh are coupled to the needle and the rod, respectively, and are guided by needles or rods at the time of human body insertion.
  • Korean Registered Patent No. 10-1635580 (registered on May 26, 2016, hereinafter referred to as 'Prior Art 3') has proposed a mesh type lifting member.
  • the above-mentioned prior art document 3 is similar to the above-described process in which a member is inserted into a human body through a process of being inserted into a human body through a needle and then retreating the needle.
  • both the basic yarn and the net yarn surrounding the basic yarn are inserted into the needle, There is a disadvantage that it gives a sense of dislike to the practitioner.
  • the suture is made into a tubular shape to minimize the diameter of the needle, and the needle is inserted into the tubular suture so that the needle of the human suture pushes the sheath of the tubular suture into the human body, retracts the needle, Research has been conducted.
  • such a direction of operation is to close the shear portion of the tubular suture so that the needle is pushed against the closed shear.
  • a method of simply welding or bonding the front end of the tubular suture or sealing the tubular suture with a separate bead member may be applied, but the tubular suture itself may be a mesh having a plurality of openings . Therefore, the pressure applied at the time of the human body may cause a disadvantage that the end of the needle is released through the side opening of the end of the tubular suture so that the tubular suture can not be inserted into the desired position. This causes the tubular suture to be inserted again, There is a problem of damaging it. Further, when a separate cap member is used to prevent the needle from deviating in the lateral direction, the volume of the additional configuration becomes large, so that the practitioner may feel discomfort due to the foreign body feeling.
  • the tubular suture is formed with tightly spaced side twist intervals of the closed front end of the tubular suture so that the needle is prevented from protruding out through the side gap in the infusion process and loosely formed in the middle portion to loosen the twist interval, And to provide a tubular suturing needle and a needle assembly for facilitating tissue regeneration.
  • Another object of the present invention is to provide a device for increasing the skin regeneration efficiency by increasing the amount of skin irritation by increasing the contact area with the human tissue upon the human body by forming a curvature on the outer surface of the tubular suture by adjusting the twist interval.
  • a tubular suture having a hollow portion manufactured by twisting a plurality of individual sutures the front end is closed, and a certain length from the closed front end to the backward unidirection is formed by narrowing the individual suture interval so as to remove the gap on the side,
  • a cone type front end portion having a cone shape;
  • a mesh part which is continuous with the cone type front end part and forms a mesh area in which the weaving interval is loosened, and communicates the inside and the outside part by the gap formed on the side.
  • a rear end finishing portion may be further formed at the rear end of the mesh portion to form a dense region in the front end direction so as to prevent loosening of the individual suture thread.
  • the individual suture twist interval of the dense region may be 40 to 100 PPI (peak per inch).
  • the front end sealing of the cone type front end may be performed by any one selected from the group consisting of an adhesive, heat welding, and ultrasonic welding.
  • the cone type front end may be formed to have a length of 5 to 50 mm.
  • the dense region and the mesh region may have different numbers of individual sutures participating in weaving.
  • Partially participating individual sutures participating in the weaving of the dense region and not participating in the weaving of the mesh region are arranged in the mesh region between the two dense regions along the outer surfaces of the continuous participating individual sutures participating in the weaving of the dense region and the mesh region And are arranged in the longitudinal direction of the straight line to connect the two dense regions on both sides of the mesh region so that continuous weaving can be performed without yarn breakage.
  • the mesh portion may be configured such that the dense region and the mesh region are repeatedly formed.
  • the dense region and the mesh region may have different numbers of individual sutures participating in weaving.
  • Partially participating individual sutures participating in the weaving of the dense region and not participating in the weaving of the mesh region are arranged in the mesh region between the two dense regions along the outer sides of the continuous participating individual sutures participating in the weaving of the dense region and the mesh region. And are arranged in the longitudinal direction of the straight line to connect the two dense regions on both sides of the mesh region so that continuous weaving can be performed without yarn breakage.
  • the individual suture may be made of polyglycolic acid (PGA), polyglactin (PGLA), polydioxanone (PDO), polyglycolide-co -caprolactone (PGCL), polylactic acid (PLLA), polylactic acid (PLA), polycaprolactone (PCL), hyaluronic acid (HA) Gold weaving, and chitosan; or a biodegradable material group composed of two or more polymerized copolymers; Nylon, polypropylene, polypropylene ethylene, teflon, and silicone.
  • a tubular suture of the present invention A needle inserted into the hollow portion of the tubular suture; And a cup-shaped needle support body integrally joined to a rear end of the needle to support the needle and having an engaging portion coupled to an injector on an inner surface of a rear end of the needle.
  • the suture side of the tubular suture is tightly formed without any clearance so that the needle sheath inside the tubular suture is prevented from protruding through the gap at the front end side of the tubular suture so that the needle of the tubular suture is stable As shown in FIG.
  • tubular suture of the present invention can be easily infiltrated into the regenerated tissue through the mesh region by dividing the tubular suture yarn into a dense region having a tight side and a mesh region having a large gap.
  • the diameter of the mesh region becomes narrower than the diameter of the dense region, thereby increasing the contact area with the body tissue in which the outer surface of the tubular suture is curved, .
  • the pressure in the human body is supported and the distortion is minimized, thereby sufficiently securing the skin regeneration space.
  • a drug or other therapeutic drug necessary for regeneration of the skin can be injected together with the needle during the procedure, and the injected drug can be fixed by the tubular suture, thereby providing an intensive treatment effect to the desired site .
  • FIG. 1 is a sectional view showing a cone type tubular suture according to the present invention
  • Figures 2 and 3a are cross-sectional views illustrating tubular sutures according to another embodiment of the present invention.
  • FIG. 3B is a state diagram showing a cross-sectional state when the tubular suture of FIG.
  • FIG. 4 is an enlarged view of a main part of a tubular suture including a partially engaged individual suture according to another embodiment of the present invention
  • 5A and 5B are cross-sectional views and a photograph showing a needle assembly according to the present invention.
  • Fig. 1 is a cross-sectional view showing a cone-type tubular suture according to the present invention.
  • the tubular suture 10 of the present invention includes a hollow portion 11, which is manufactured by twisting a plurality of individual suture yarns 20 at an intersection, Is formed long in the longitudinal direction.
  • the individual suture is generally used as a suture and is provided in a general thickness.
  • the individual suture 20 may be formed by combining various types of monofilaments made of a single strand, multifilaments made of strands, protruding monofilaments having protrusions on the outer surface, monofilaments or multifilaments twisted or knotted, Because it can be provided in various thicknesses, it can provide the necessary supporting force for the tubular suture.
  • the tubular suture 10 of the present invention comprises a cone type front end portion 30 having a dense region 12 in which a gap is removed by adjusting the spacing of individual suture threads and a mesh region 13 in which the inner and outer portions communicate with each other through a gap And a mesh portion 40 formed thereon.
  • the cone type front end portion 30 of the present invention has a cone shape in which a predetermined length is formed as a dense region 12 in a rear single direction from a closed front end, And a meshed region 13 is formed which is woven at a loosely spaced interval so as to enlarge the side clearance so that the inside and the outside are communicated with each other.
  • the dense region forming the cone type front end portion 30 is formed by narrowing a plurality of individual sutures crossing each other at a narrow interval so as to remove a gap on the side, and at least a twist interval is set to 40 PPI (peak per inch) So that the needle can be prevented from protruding to the outside through the twist interval by the pressure.
  • the twist spacing is woven to have a density of 100 PPI or more, the individual suture is overlapped with multiple layers, so that the thickness is excessively increased, which may lead to a large entrance of the human body, It is preferable to use one having a PPI of 100 PPI or less. (In the experimental example, when the twist was formed at an interval of 40 PPI or more, it was possible to prevent the needle from protruding to the outside with respect to the left and right twisting pressure with respect to the inserted needle.)
  • the dense region 12 is formed to have a predetermined length from the closed front end to the rear end direction in the tubular suture, and the front end can be sealed by various known techniques of adhesion and fusing, Fusion bonding, ultrasonic fusion bonding, or the like. In this case, it is preferable to minimize the fusing surface in the heat fusion or ultrasonic fusion.
  • Various known types of adhesives can be used, but Loctide 4014 or Elvamide, which is a medical adhesive harmless to the human body, is preferably used. It is also possible to use an adhesive component that melts and fuses or bonds the material.
  • the cone type front end portion 30 formed as a dense region and having the side through holes removed has a structure for wrapping the needle front end where a large pressure acts upon coupling with the needle 60, the needle passes through the side of the tubular suture during the human skin insertion process So that it can be prevented from being projected.
  • the length of the cone type front end portion 30 is preferably about 20 to 40% of the length of the tubular suture. In general, when the tubular suture is attached to the needle, It is preferable that the length is formed within a length of 50 mm. In this case, the length of the side of the needle front is shorter than 5 mm, so that the front end of the needle can be separated from the front end of the cone type by the sway of the left and right sutures.
  • the length of the mesh portion which is an area communicating between the inside and the outside, is shortened. Therefore, it is preferable to form the length of the cone type front end within the above range.
  • the meshed portion 40 is formed by continuous weaving from the cone-shaped front end portion 30, but is formed in a mesh form having loosened twist spacing more than the cone type front end portion, so that the hollow portion communicates with the outside, So that the inflow can be facilitated.
  • the mesh region forming the mesh portion has a twist interval of 10 to 60 PPI so that the regenerated cell tissue can be easily introduced. Providing a twist spacing of 10 PPI or less is difficult to maintain the inner hollow portion of the tubular suture due to a reduction in the supporting force. If the twist spacing is more than 60 PPI, it takes a long time for the regenerating cells to flow in It is preferable to provide the above range. In this case, the twist interval in the range of 40 to 60 PPI is a gap in which the needle can not protrude, and the twist interval of the mesh area and the dense area narrows the twist interval of the dense area, Can be loosely formed.
  • the cone type tubular suture 10 of the present invention may further include a rear end finishing portion 50 that forms a dense region in the front end direction from the rear end.
  • the rear end finishing portion 50 prevents the loosening by densely forming the individual suture thread spacing at the end portion of the mesh portion 40 and facilitates insertion of the needle 60 into the hollow portion 11 of the tubular suture 10 .
  • the length of the rear end finishing portion 50 is preferably about 20 to 30% of the entire length of the tubular suture 10.
  • the length of the rear end finishing portion 50 is set by using a tubular suture attached to the needle, It is preferably formed within a length of 5 to 40 mm. In this case, it is difficult to provide an effect of preventing loosening of the individual suture thread within the above-mentioned 5 mm, and when the length is 40 mm or more, the length of the mesh portion, which is an area communicating the inside and the outside of the tubular suture, is shortened. .
  • the mesh portion 40 may be formed by repeatedly alternating mesh networks in which loosely woven individual suture yarns are formed or dense regions and mesh regions.
  • the dense region 12 and the mesh region 13 are alternately repeatedly formed in a short section, as shown in FIG. 3A.
  • pressure is applied to the entire outer surface of the tubular suture 10, and the dense region 12 having a relatively high structural strength has a large repulsive force against the internal pressure, ) Is weak in structure strength due to loose weaving, so that it is pushed inward when the internal pressure acts, and the diameter is reduced.
  • the outer surface of the mesh portion 40 in which the dense region 12 and the mesh region 13 are alternately formed, is formed to be bent.
  • Such a curved surface increases the contact area with the human tissue and can promote more tissue regeneration by transmitting more stimulation to the human tissue due to the increased contact area.
  • the curvature of the mesh portion also serves to fix the position of the inserted tubular suture.
  • the dense region 12 and the mesh region 13 can be woven with different strands of individual sutures.
  • the dense region 12 is woven with 8, 12, 16, and 24 strands of individual sutures, and the mesh region 13 is formed by a variety of combinations, such as weaving with 4, 6, 12 strands of individual sutures,
  • the mesh regions can be woven with different numbers of strands.
  • the dense region 12 may provide a short length of individual sutures to increase the number of strands to densely form the twist spacing, but to provide continuity, the dense region may include both individual sutures in the weave, , It is possible to control the twist interval in the two regions by allowing only a part of the individual sutures to participate in weaving.
  • the partially participating individual suture yarn 21, which participates in the weaving of the dense region but does not participate in the weaving of the mesh region is formed by weaving the dense region and the mesh region in the mesh region between the two dense regions It is possible to connect the two dense regions on both sides of the mesh region in a continuous lengthwise direction along the outer surface of the continuously participating individual suture yarn 22, which are all participating, in a straight line.
  • the partial participating individual suture not participating in the mesh weaving is a continuous participating individual suture participating in the mesh region weaving Extending in the longitudinal direction along the outer surface so as to allow continuous weaving.
  • the partial participating individual suture 21 forms the outer surface of the continuous participating individual suture 22 So that the partial participating individual suture and the continuous participating individual suture are continuously woven.
  • a temporary skin regeneration space is formed using a biodegradable material and then decomposed and removed.
  • a non-biodegradable material is used to enter the skin along with regenerated skin, And a pulling force, or a mixture of a biodegradable material and a non-biodegradable material may be used.
  • biodegradable material examples include polyglycolic acid (PGA), polyglactin (PGLA), polydioxanone (PDO), polyglycolide-co (co-caprolactone -caprolactone (PGCL), polylactic acid (PLLA), polylactic acid (PLA), polycaprolactone (PCL), hyaluronic acid (HA) Gold weaving, chitosan, or a copolymer of two or more kinds of polymers, may be used alone or in combination of two or more.
  • PGA polyglycolic acid
  • PGLA polyglactin
  • PDO polydioxanone
  • PDO polyglycolide-co (co-caprolactone -caprolactone
  • PGCL polylactic acid
  • PLA polylactic acid
  • PCL polycaprolactone
  • HA hyaluronic acid
  • Gold weaving chitosan, or a copolymer of two or more kinds of polymers, may be used alone or in combination of two
  • nylon, polypropylene, polypropylene ethylene, teflon, and silicone may be used alone or in combination of two or more.
  • a needle assembly 100 according to the present invention is provided in the form of a tubular suture 10 having the dense region and the mesh region mounted on a needle 60. That is, in order to use the tubular suture 10 of the present invention, it is necessary to insert the tubular suture 10 into the needle 60. However, since the tubular suture 10 is not easily performed in the field, The needle assembly 100 may be provided in the form of a needle assembly 100 pre-mounted on the needle assembly 100.
  • the needle 60 is inserted from the front end into the hollow portion 11 of the tubular suture 10 so that the tubular suture is wrapped around the outer surface of the needle and the rear end of the needle 60 is supported by the needle support 70.
  • the needle support 70 serves as a handle for holding the needle of a human body or an injector such as a syringe is additionally provided on the inner surface of the needle support to easily inject drugs or inject necessary components for skin regeneration You can.
  • the engaging portion may protrude from the inner surface of the needle support in a ring shape so that the engaging portion can be engaged with the injector or can be engaged with the injector.
  • the tubular suture serves as a reservoir for storing the injected drug for a certain period of time. Therefore, the drug is slowly transferred to the outside to promote tissue regeneration at a specific site, Treatment can be performed.
  • the usable needle may be selected from a variety of well-known needles, and preferably any one of the needles having blunt end R-Blunt, L-Blunt, W-Blunt, A-Blunt and Sharp cannula is selected and used will be.

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Abstract

La présente invention concerne une suture tubulaire de type cône et un ensemble aiguille l'incorporant et, plus particulièrement, une suture tubulaire de type cône et un ensemble aiguille l'incorporant, une suture tubulaire avec une forme tubulaire ayant une surface de maille étant fabriquée par torsion d'au moins deux sutures individuelles à une intersection et par formation d'une partie creuse dans laquelle un tube d'aiguille est introduit; l'extrémité avant de la suture, guidée par le tube d'aiguille introduit dans la partie creuse et d'abord insérée dans un corps humain, étant formée avec un type de cône par formation étroite d'un intervalle de torsion de suture de façon à empêcher le tube d'aiguille de dévier vers le côté à travers un espace entre des sutures individuelles pendant le processus d'insertion; et l'intervalle de torsion de suture étant formé de manière lâche dans la partie médiane de la suture tubulaire de telle sorte que l'introduction de tissu humain régénéré dans la partie creuse à l'intérieur de celle-ci peut être facilitée, de façon à améliorer l'effet de remplissage de tissu.
PCT/KR2017/012819 2017-11-10 2017-11-13 Suture tubulaire de type cône et ensemble aiguille l'incorporant WO2019093555A1 (fr)

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KR10-2017-0149442 2017-11-10
KR1020170149442A KR102057894B1 (ko) 2017-11-10 2017-11-10 콘타입 관형봉합사 및 이를 결합한 니들 조립체

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KR102534808B1 (ko) * 2020-01-15 2023-05-19 가톨릭관동대학교산학협력단 생분해성 봉합사 및 이를 포함하는 수술용 봉합사

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EP2275148A1 (fr) * 2004-06-14 2011-01-19 Teleflex Medical Incorporated Suture à haute résistance
US20120197294A1 (en) * 2011-02-02 2012-08-02 Martin Daniel L Variable denier yarn and suture
KR20140127333A (ko) * 2012-02-23 2014-11-03 노오쓰웨스턴 유니버시티 개선된 봉합물
US20150051643A1 (en) * 2008-06-24 2015-02-19 Bioactive Surgical, Inc. Surgical sutures incorporated with stem cells or other bioactive materials
WO2016148904A1 (fr) * 2015-03-17 2016-09-22 Advanced Suture, Inc. Fil de suture en treillis présentant des caractéristiques antiboudinage

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