WO2019091961A1 - Procédé de contrôle et équipement de contrôle - Google Patents

Procédé de contrôle et équipement de contrôle Download PDF

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Publication number
WO2019091961A1
WO2019091961A1 PCT/EP2018/080291 EP2018080291W WO2019091961A1 WO 2019091961 A1 WO2019091961 A1 WO 2019091961A1 EP 2018080291 W EP2018080291 W EP 2018080291W WO 2019091961 A1 WO2019091961 A1 WO 2019091961A1
Authority
WO
WIPO (PCT)
Prior art keywords
instrument part
instrument
holder
contact pressure
pressing
Prior art date
Application number
PCT/EP2018/080291
Other languages
German (de)
English (en)
Inventor
Andreas Wild
Lothar Müller
Original Assignee
Ma Micro Automation Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ma Micro Automation Gmbh filed Critical Ma Micro Automation Gmbh
Publication of WO2019091961A1 publication Critical patent/WO2019091961A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/95—Investigating the presence of flaws or contamination characterised by the material or shape of the object to be examined
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips

Definitions

  • the invention relates to a method for assessing the delay of an elongated instrument part such as a pipette tip and a test device for carrying out the method.
  • a distortion of an elongated instrument part often significantly impairs the use of the same or the instrument part with the instrument part and is often absolutely necessary for a quality control of the instrument part.
  • this may only have a relatively small delay in the longitudinal direction, so only a slight deviation from the linear nominal shape.
  • Such pipette tips are used, for example, in the field of medical technology in automatic pipettes, wherein the medium applied by the pipette medium is applied as exactly as possible at the application site, for example in the center of the recess of a microtetra plate. Even relatively small deviations from the predetermined application site can distort the results of the experiment conducted by ⁇ or lead to an undesirable scattering of the experimental results under certain circumstances.
  • an undesirable delay pipette can also quantity dosage of metered medium beeinflus ⁇ sen circumstances.
  • Especially in the field of medical technology are therefore only comparatively small tolerances with respect to the geo ⁇ metrical design of the instrument part as a Pipet ⁇ ten dictate allowed, but partly also in other technical ⁇ ranges rule.
  • the determination of the target position of the pipette tip outlet openings by means of the second image capture means aligned with the inlet opening of the upper pipette tip end has in practice proven to be partially difficult or error-prone.
  • the tolerances in determining the desired position of the pipette tip with the second image capturing means and the tolerances of the determination of the actual position by means of the first Bilder chargedsmit ⁇ tel overlap each other, which leadership to inaccuracies in the determination of the actual deviation of the pipette tip delay ren can.
  • inaccuracies of the holder lead the Pipette tip at derem inlet end that the second image capture means not reliably detect the desired position and the pipette tip is considered an exclusion or the measurement process is much more difficult.
  • the difficulty of determining the distortion of the elongated instrument part is enhanced if it consists of a dark, in particular black material, since then the boundary edges of different sections of the instruments instrument part are difficult to see visually due to lack of contrast or difficult to detect by means of image acquisition means.
  • the invention is therefore based on the object, a reliably transmitting measurement method for the delay of elongated instrument parts such as in particular the pipette tips provide admirzu ⁇ , the method is fast and reliable and can be carried out with little effort in relation to the required for this test ⁇ device. Furthermore, the object is to provide a test device suitable for carrying out the method.
  • the object is achieved by the method and the test apparatus according to the independent claims 1 and 10, wherein advantageous developments each result from the dependent claims.
  • the testing device to be appropriate to carry out the process facilities, so that was taken in relation to the constructive Ausgestal ⁇ processing of the testing device on the comments on the implementation of the method according to reference.
  • the method is carried out such that the instrument part by means of a pressing device, preferably a pressing device of the test device, with application of force against the instrument part holder of Testing is pressed orcardi and that said Mes ⁇ solution of the positional deviation for determining the delay of the instrument part is given after the instrument portion was pressed with a pressing force or a pressing force of the Anpressein- direction against the tool part holder, preferably while the instrument part with a Anpress ⁇ pressure or a pressing force of the pressing device is pressed against the instrument part holder.
  • a pressing device preferably a pressing device of the test device
  • the area of the instrument part (ie the holding area thereof) received in the holder can have a certain distortion or certain irregularities of the shape in deviation from an ideal instrument part (without such deviations from the desired shape).
  • These deviations of the desired shape for example, a certain distortion of the instrument part in the longitudinal direction is, make ⁇ so that the holding area so different from the linear nominal shape.
  • These deviations may, however, also represent, for example, local bulges at the holding area of the instrument part or certain changes in the cross section of the instrument part.
  • sectional shape for example, a non-round, such as oval cross-sectional shape instead of a circular cross-section according to the desired shape of the holding portion of In ⁇ strumententeils, or, for example, a relation to the desired shape enlarged cross section or diameter and the like.
  • the tilt is canceled by pressing the instrument part against the holder and the instrument part is pressed into its desired position.
  • the instrument part is inserted into the holder, for example.
  • Jammed or the instrument part is plastically deformed by the pressing ⁇ pressure or the pressing force or it ⁇ sufficiently slowly followed by the provision of an elastically deformed instrument part, it may already be suffi ⁇ accordingly, the instrument part only press against the holder before measuring to achieve the stated advantages.
  • the inventive method is thus particularly advantageous way at ⁇ instrument parts applicable, which are plastically or elastically deformable, so that, by the pressing force of the holding portion of the instrument part, the mounting of the test apparatus adapts.
  • the instrument part is thus preferably plastically or elastically deformable under the pressing force of the pressing device.
  • the method may be used for instrument parts made of a plastic material. al be used.
  • the inventive method may in manufactured by injection molding or extrusion processes instrument parts to be applied (especially plastic parts) in which the result of the shrinkage of the instrument part during its cooling to Jardintem ⁇ temperature and / or due to tolerances or inaccuracies in the manufacturing variations of the actual from Target shape of the instrument part can result. Said elasti ⁇ cal or plastic deformation in the holding area of the home be strumententeils or the entire instrument part gege ben ⁇ .
  • inventive method and the dung OF INVENTION ⁇ proper testing are orcardi particularly suitable to reliably detect even the delay of dark, especially black, Instrumententei ⁇ len or identify.
  • the holding portion of the instrument part understood as the holding portion of the instrument part to the holder of the test apparatus.
  • the “fastening region” of the instrument part is generally the area for mounting the instrument part understood at the Instru ⁇ element, say for example.
  • In a Pipette As "elongated instrument part” in the sense of OF INVENTION ⁇ dung is understood in particular, in which the length of the tool part is greater than / equal to a factor of 3 or greater than / equal to the factor of 5 or greater than / equal to 10 times the outer diameter of the instrument part corresponds such speaks without being limited thereto.
  • a "contact pressure” in particular a "predetermined Anpressdru ⁇ ckes” corresponding to "pre-defined contact force” is also a “contact force” or understood.
  • the instruments ⁇ part is particularly preferred in the process is pressed in the shaft longitudinal direction of a shank of the tool member against the tool holder of the test apparatus, so that the said measurement of the positional deviation for the determination of the delay may be carried out after this pressing or during the pressing of the instrument part to the support or is carried out.
  • the shaft ⁇ length may be greater than / equal to correspond to greater than / equal to the factor of 5 or greater than / equal to 10 times the outer diameter of the instrument portion by a factor of 3 or, without being limited thereto be ⁇ .
  • the shaft may be a hollow shaft, wel ⁇ cher can easily forgiven.
  • the instrument part is pressed during the measuring operation by means of the pressing against the instrument holder part with a contact pressure or a contact force, so that during the measuring process a secure and precise defined seat of the instrument part is secured to the holder, especially if the pressed-on instrument part restoring forces exerts the pressure, which could change the exact seat.
  • the instrument part upon initiation of and during the entire measurement procedure is pressed by means of at ⁇ pressing means against the instrument panel fixture with a contact pressure, or a pressing force whereby the method is particularly reliable.
  • the measuring process is checked over ⁇ that the instrument part is pushed by means of the Anpressein ⁇ device with a predefined contact pressure or predefined pressing force against the instrument panel fixture, before the measurement is enabled or carried demonstrates implementation.
  • the check is preferably carried out by means of a measuring sensor, which measures the contact pressure or the contact pressure of the instrument part against the holder, so that the compliance of the contact pressure or the contact force determined independently of other process parameters and the method is particularly reliable.
  • a pressing device configured in this way, which displays the contact pressure or pressing force exerted by the latter on the instrument part, for example on the basis of a measurement of this contact pressure or of this contact pressure or merely on the basis of the setpoint value of the contact pressure device being set.
  • the triggering of the measuring process can then generally occur when the check is positive in fulfillment of the desired size of the contact pressure.
  • the check may additionally or alternatively be performed during and / or after the end of the measuring procedure.
  • the display or control described below may be used.
  • the contact pressure or the contact pressure of the instrument part against the holder can also be generated by placing a weight on the instrument part which presses it against the holder.
  • the measuring device for carrying out a measuring process can ensure that, before and / or the instrument part experiences the traystimm ⁇ th contact pressure or contact pressure during the measuring process, wherein the measure- ment eg.
  • the display can be performed manually or automatically by means of the control.
  • the contact pressure or contact pressure of the Anpressein- direction against the tool part by means of a signal ⁇ transmission device of the testing device used by the signal transmission device a signal to the measuring device or to the control for executing the method in Depending ⁇ ness, wherein the measurement of the delay performed the instrument part, or the measurement device for carrying out such a measurement is activated when the measuring device of the Signalübertra ⁇ restriction device receives such a signal.
  • the instrument part is pressed against the holder with an outgoing , preferably a predetermined, contact pressure or pressing force of the pressing device when the delay is measured by means of the measuring device.
  • the activation of the measuring device on the basis of said signal reception means that the measurement process can be triggered itself independently of the time of signal reception, for example, manually or by means of ei ⁇ ner measurement with a certain, preferably predetermined, time delay from the time of signal reception.
  • the measurement process of the delay can be carried out directly, for example, automatically, if the measuring device receives said signal from the signal transmission device.
  • Said signal reception can be displayed by a ent ⁇ speaking display of the testing device, for example one, including a display of a data processing unit the direction of the optical measuring device and / or audible indication.
  • the inventive method can thus also be automated as part of the industrial manufacturing process of the instrument part or be carried out using a ⁇ of individual samples.
  • the method is preferably such out from ⁇ that the signal transmission means transmits a signal to the measurement device or the control for activating or performing a measuring process, if the pressing with a predetermined pressure or a predetermined pressure force presses the instrument part opposite the holder, For example, with a predetermined constant setpoint.
  • the pressure or pressing force or the corresponding predetermined target value may be determined in depen ⁇ dependence of the formation of this instrument part, in particular depending on the shape of shape and / or plastic and / or elastic properties. This ensures a secure fit of the instrument part during the measuring process.
  • the setpoint value can be determined empirically, for example by examining whether there are effects on the accuracy of the measurement of the distortion of a given group of instrument parts by means of the method according to the invention for a given series of contact pressure actual values or contact force actual values of different sizes.
  • the actual distortion of the individual instrument parts of the group is measured by another measuring method, for example by means of a mechanical scanning device - possibly with prior calibration of the measuring device by means of a distortion-free instrument part as standard, as described below.
  • the contact pressure of the instrument part against the holder can be, for example, in the range of 0.25-20 N or up to 10 N, preferably 1-5 N, in particular in the range of 2-3 N, without being limited thereto.
  • the contact pressure of the instrument part against the holder can result from the abovementioned pressing force, wherein the area to be used for determining the pressure is the cross-sectional area of the instrument part whose boundary is pressed against the holder.
  • the measuring method can be carried out in such a way that the signal transmission device sends a signal to the measuring device when the pressing device presses the instrument part against the holder as a function of a changing contact pressure or changing contact pressure and thereby changes the position of a predefined area of the instrument part Depending on the contact pressure or contact force of a predetermined characteristic follows.
  • Said pre-defined region of the instrument part can in this case in particular of the Hal ⁇ esterification its opposite end region of the tool part, in particular the opposite of the mounting end of the instrument part, for example in the case of Pipet ⁇ tenspitze the region of the outlet opening thereof, or the outlet or the outlet opening of the pipette tip but For example, an inlet opening such as pipette tip inlet opening, the attachment area of the instrument part or the like.
  • the instrument part is used to measure the delay ⁇ in a holder of the test apparatus, which holds without the action of the pressing on the instrument part this backlash in the holder, preferably laterally backlash, particularly preferably allowing a change in position of the instrument part in the longitudinal direction opposite the holder, eg. against the direction of gravity.
  • the instrument part is in this case in all directions perpendicular supported for its longitudinal direction free from play in the holder, to which the Hal ⁇ esterification may surround the instrument part fully, preferably under more fully engagement therewith, whereby even in a delay of the holding portion of the Instru ⁇ management part is under the action of the contact force or the contact pressure results in a well-defined positioning of the In ⁇ strumententeils on the holder.
  • the pressing device without the action of the pressing device on the instrument part, it is held in the holder in a form-fitting, particularly preferably exclusively form-locking manner. tert. Subsequent to the positive retention of the instrument part in the holder, the instrument part is then pressed by means of the pressing device against the holder.
  • this does not counteract the contact pressure or the contact pressure of the pressing device against the instrument part, and thus achieves a particularly defined holder for the measurement. Furthermore, this allows the instrument part to be placed on the bracket simply loose in this and is then transferred by the said contact pressure or contact force in its defined desired position and / or fixed in this.
  • the holding region of the instrument part is preferably arranged on the holder at an end region of the instrument part, which can be opposite the end region of the instrument part whose positional deviation from the desired position of the instrument part is measured by means of a position detection device, in particular an image capture device.
  • a position detection device in particular an image capture device.
  • the holding area of the instru ment ⁇ partly on the holder of the testing apparatus in the area of the attachment region of the instrument part to Festle ⁇ supply the same to the associated instrument is given, for example. Adjacent thereto. This allows the instrument part to be aligned precisely and predefined during the measurement. so that the distortion with low measurement tolerance and particularly reproducible measurable.
  • Said fastening ⁇ area usually also has an increased mechanical Stabili ⁇ ty, so that the pressing is preferably pressed against the attachment region.
  • the method is carried out such that by means of the contact pressure or the contact pressure of the instrument part to the holder, the instrument part is pressed with a stop against the holder, whereby a particularly accurate positioning of the instrument part when pressing against the holder results.
  • the instrument part can be pressed in the longitudinal direction by a certain extent in the holder by the contact pressure or the contact force until said stop of the instrument part comes to rest with the holder.
  • a derarti ⁇ ger stop of the instrument part for example, represent a portion of the mounting portion of the instrument part of the associated instrument, such as an annular flange of the instrument part, with which this is fixed to the instrument.
  • the instrument part is particularly preferably used in an esterification Hal ⁇ which strumententeils this or a shaft of the home at two spaced in longitudinal direction of the
  • the two spaced apart in the longitudinal direction of the shaft holding portions of the holder thus each preferably have a cross section, which is adapted to the cross section of a distortion-free instrument part in the respective holding area to laterally backlash in a predefined direction to support the respective holding area.
  • the holder mount particularly easy to produce, in particular when the holding region of the instrument part extends over the longitudinal direction of the holder receptacle (which runs parallel to the longitudinal axis of the instrument part accommodated in the holder), for example if the instrument part is conical or generally not in its holding region is formed cylindrically.
  • the bracket jig can for this purpose be formed in ⁇ play of two perforated plates with different hole diameter, wherein the perforations are arranged coaxially with each other.
  • more than two holding regions spaced apart from one another in the longitudinal direction of the shank can also be provided on the holder, particularly preferably exactly two.
  • the distance of the two Garbe ⁇ rich each other in Instrumententeillkonsraum is preferably substantially smaller than the length of the instrument part, for example ⁇ 25% or ⁇ 15%, preferably ⁇ 10% or ⁇ 5% of the same or its shaft length.
  • the holder of the measuring device for the instrument part may have a retaining pin, on which the instrument part is placed in order to align it during the measurement with respect to the position detection device, such as an image capture device.
  • the retaining mandrel preferably engages in a recess of the instrument part, for example a passageway of the same, for example the passage channel of a pipette tip.
  • the instru ment ⁇ part positively and / or non-positively supported on the holding mandrel, particularly preferably only a form-fitting, apart from the pressing of the pressing part against the tool before and / or during the measurement of the delay.
  • the exporting ⁇ approximations can apply generally corresponding to the holder, in particular also to the arrangement of two spaced-apart in the longitudinal direction of the shank holding portions.
  • an image capturing device is preferably used, whose optical axis during the measurement of warpage in parallel, preferably coaxially to the longitudinal axis, game as examples shank longitudinal axis of is oriented in the holder salaries ⁇ th instrument part.
  • the expenditure on apparatus of the respective test device is comparatively low and at the same time determined the delay of the instru ment ⁇ part with high accuracy and reproducibility.
  • the image detection means and the pressing means can thus for pressing the tool member against the bracket to each other fringelie ⁇ constricting end portions of the instrument part to be arranged so that the arrangement of the pressing device is not impeded at one end of the instrument portion by a possible second Bil ⁇ der chargeds adopted in this area.
  • an image capture device is particularly preferred in metrological terms and in relation to a production process of mass production.
  • the measuring device can instead an image detection device also have a different position detection device which detects the actual position of the predetermined region of the instrument part in order to be able to determine the positional deviation from the predefined desired position with regard to a possible distortion.
  • the position detection device can, for example, have a coordinate system, wherein the desired position of the predetermined region of the instrument part, such as, for example, a pipette tip, can lie in the origin of the coordinate system.
  • the coordinate system can be, for example, an xy-coordinate system or another coordinate system with two or possibly more coordinates.
  • the coordinates of the actual position of the predetermined area can be determined, for example, by suitable sensors or buttons, for example also by line sensors.
  • the method includes that a distortion-free Instru ⁇ management part is provided, thus having no deviate ⁇ deviations from the desired shape of the instrument part and can therefore be used as a standard or the definition of the distortion-free zero point.
  • This variant is also generally advantageous in a method or device according to the preambles of claims 1 and 10.
  • the distortion ⁇ free tool part can thus a are to be examined using the instrument part for calibrating the measuring ⁇ means for determining the delay, preferably also the warping instrument part before and / or during the measurement of delay through the pressing device is pressed against the holder, so that the measurement of the distortion-free instrument part as a standard and the instrument parts whose distortion is to be determined are examined under the same measuring conditions.
  • the used for calibration instru ⁇ ment part must be made not necessarily by the same manufacturing process ⁇ how to be examined in relation to the United ⁇ train instrument parts. It is understood that the calibration instrument part may be replaced by suitable chanical post-processing and measuring method with respect to its shape shape as for example by means of suitable scanning devices in its nominal form can be produced. The delay can then, for example, be determined as the distance of the position of the free end of the examined instrument part
  • the in respect to the delay toomme ⁇ sponding instrument part a shaft, which it extends ⁇ over a larger part of the length of the instrument part, for example to> 25% or> 50% or> 75% or> 80% of Length of the same.
  • the shaft may be formed as a hollow shaft, for example in the form of a
  • Pipette tip possibly also as a solid shaft.
  • the shank of the tool part may comprise a conical shape aufwei ⁇ sen or conical longitudinal sections, optionally also have a cylindrical or other shape. The delay can be true with respect to a free end of the shaft ⁇ be.
  • a test fixture with multiple holder can be used to measure a plurality of instrument parts simultaneously with respect to their distortion.
  • the plurality of instrument parts can be mounted on the holder in the inventive method particularly simple and fast, for example.
  • a revolving mechanism in each case a single, secured instrument part can be supplied to the pressing device, for example, in which the holder is so positioned.
  • the multi-compartment holder also several instrument parts at a time by an appropriately constituted measuring device with respect to the delay of the respective instrument part ver will measure ⁇ , for example, by the fact that according to the number of the held on the holder tool parts to an equal number of image acquisition devices the measuring device is provided.
  • the pressing device can in this case be designed in such a way that it applies force to a single or several or all of the instrument parts arranged on the holder and presses against the holder, for example at the same time or one after the other, for which purpose the pressing device can, for example, have a suitable stamp.
  • the holder can in this case be variable in position is formed, for example. With a carriage, in each case to arrange a single instrument part from the group of a plurality of Tei ⁇ len to the image capture device for the measurement.
  • the pressing device may also be designed in the form or in the manner of a cam disk, said un ⁇ ter movement such as by rotation or translational tive movement of the cam disc in each case a single or a group of tool parts is pressed against the holder and with respect to this tool parts then the measuring process is carried out.
  • the inventive method is in particular for a quality monitoring of the tool parts in the course of an industrial process suitable Her ⁇ position.
  • the inventive method is particularly geeig ⁇ net, to be integrated in an industrial production process for manufacturing position of the tool parts.
  • manufactured instrument parts can be easily fed by conventional transport devices of the holder of the measuring device.
  • the feeding can take place directly from the shaping device to the holder, or the instrument parts produced by the shaping method can first be collected in a collecting device and then singulated and fed to the measuring device by means of a suitable transport device, whereby this also applies to a group of Parts of the instrument can relate.
  • the holder Due to the fact that the instrument parts are only positively positioned in the holder before use of the pressing device, if necessary also comprising a multiple holder, the holder can be equipped particularly simply and quickly with the instrument parts.
  • the instrument parts can be supplied by means of a louver ⁇ ⁇ lungs worn under the action of gravity of the holder, for example by means of a simple slide, via which the instrument parts guided in the
  • FIG. 1 shows a test device 1 according to the invention for assessing the distortion of an elongated instrument part 2 such as a pipette tip for carrying out the method according to the invention.
  • Figure 2 shows the view ei ⁇ nes instrument part in the longitudinal direction with delay.
  • the device 1 comprises a holder 3 for the tool part 2, by means of which the In ⁇ strumententeil is supported goes on these 2 with its longitudinal direction at least We ⁇ sentlichen along a predefined preferred direction of the device 1 can be aligned, for example. In the direction of gravity.
  • the device 1 further has a measuring device 5 which measures the distortion of the instrument part as a positional deviation of a predetermined region of the holder part held in the holder 3 from a predefined desired position of this region with a distortion-free instrument part.
  • the predetermined range based on which the delay is measured, is in this example, the holder opposite free end of the instrument part, in the case of a pipette tip ⁇ the outlet or the outlet opening.
  • the instru ⁇ ment part 2 in this case has a mounting portion 2a for attachment to the associated instrument such as a pipette and an elongated shaft 2b, which may represent a hollow shaft as in the case of a pipette tip, and thus an inlet opening 2c and at the free end 2d an ⁇ opening 2e.
  • the instrument part or the elongated shaft 2b thereof may be in arrears, ie
  • Deviation from the rectilinear ideal shape so that due to the distortion, the instrument part or its shaft, for example, arc-shaped.
  • This distortion thus leads to the said position deviation A of the free end 2d to the ideal shape or to the longitudinal direction L (P) of the test device 1 or its holder 3, for example.
  • L (P) of the test device 1 or its holder 3 for example.
  • a lateral position deviation as shown in Fig. 2.
  • a measuring device 5 which has an image capture device 6, such as a camera, with which the position of the free end 2d can be detected, or its lateral distance to the longitudinal axis of the instrument part with ideal shape, which in this case coincides with the longitudinal direction L (P) of the test device 1.
  • the optical axis of the image capture device 6 is aligned parallel to the longitudinal axis or the shaft longitudinal axis of the held in the holder 3 Instru ⁇ ment part 2 during the measurement of the delay.
  • End 2d be provided to determine the position deviation of the desired position.
  • the test device has a Anpressein- direction 7, by means of which the instrument part 2 with
  • the contact pressure against the instrument is particularly advantageous. Maintained during the entire measurement period, resulting in particularly reliable test results.
  • the instrument part may consist of an elastically or plastically deformable material, such as a plastic material, which may be deformable under the contact pressure. In the context of the embodiment can respectively at ⁇ point of the contact pressure and a pressing force are used, and vice versa.
  • the measuring device 5 further comprises a display or STEU ⁇ tion 8, which in response to the contact pressure of the pressing device 7 against the instrument part 2, the measuring ⁇ device 5 for activating to perform a measuring operation releases or fourth obliget to perform a measurement.
  • the display can, for example, indicate that the An ⁇ contact pressure against the tool body reaches a predetermined set point, whereupon eg.
  • the measurement process is triggered manually back. Accordingly, upon reaching the specified setpoint value of the contact pressure by means of the control, for example, the measuring method can be automatically initiated and carried out.
  • the test device 1 further has a signal transmission device 9, which emits a signal to the measuring device 5 as a function of the contact pressure of the pressing device 7 against the instrument part 2.
  • a signal transmission device 9 which emits a signal to the measuring device 5 as a function of the contact pressure of the pressing device 7 against the instrument part 2.
  • the signal transmission device 9 transmits a signal to the measuring device 5 when the pressing device 7 with a predetermined contact pressure pushes the instrument part 2 against the holder 3 or when depending on a changing contact pressure of the instrument part against the holder 3, the change in position of a predefined area of the instrument part as a function of the An ⁇ pressing pressure of a predetermined characteristic follows.
  • the holder 3 holds the in these used Instrumen ⁇ tenteil 2 laterally without play and positively, said instrument part is longitudinally displaceable against the bracket 3, before it is pressed by the pressing means 7 against the support.
  • the instrument part is preferably held in the holder only without play, for which purpose, for example, it can be inserted loosely into the holder.
  • the holding portion 2h of the instrument part may in this case be conical or widen at the holding end of the instrument part with increasing distance from the holding ⁇ tion or have a paragraph to rest on the holder. By pressing the instrument part is centered in the holder 2 at the same time.
  • the holder 3 can have two holding regions 3a, 3b which are spaced apart from one another in the longitudinal direction of the holder and can each engage the instrument part for holding the same. As a result, the instrument part can be particularly easily aligned with the test device.
  • the holding portions 3a, 3b are formed here as perforated plates with coaxial alignment of their holes.
  • a distortion-free instrument part (not Darge ⁇ represents) is provided, which corresponds to the distortion-free ideal shape of the instrument part and by means of which the measuring ⁇ device 5 can be calibrated to determine the delay of a to ban ⁇ sponding instrument part.
  • the distortion-free instrument part as standard under the same measuring conditions as the instrument part to be tested, ie also the same contact pressure, so that a zero point for determining the positional deviation due to the distortion is defined for the image detection device.
  • a zero point for determining the positional deviation due to the distortion is defined for the image detection device.

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
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  • Length Measuring Devices By Optical Means (AREA)

Abstract

La présente invention a trait à un procédé pour estimer la déformation d'une partie allongée d'un instrument, telle qu'une pointe de pipette, au moyen d'un équipement de contrôle ainsi qu'à un équipement de contrôle. La partie d'instrument est maintenue et orientée sur un support de l'équipement et au moyen d'un dispositif de mesure de l'équipement de contrôle, une déformation de la partie d'instrument est mesurée en tant que déviation de position d'un secteur prédéterminée de la partie d'instrument par rapport à une position théorique prédéfinie de ce secteur d'une partie d'instrument sans déformation. Selon l'invention, la partie d'instrument au moyen d'un dispositif de serrage de l'équipement de contrôle est serrée par application d'une force contre le support de pièce d'instrument de l'équipement de contrôle et la mesure de l'écart de position est effectuée pour déterminer la déformation de la partie d'instrument après que la partie d'instrument a été pressée avec une pression de serrage du dispositif de serrage contre le support de pièce d'instrument.
PCT/EP2018/080291 2017-11-09 2018-11-06 Procédé de contrôle et équipement de contrôle WO2019091961A1 (fr)

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DE102017126277.6A DE102017126277B3 (de) 2017-11-09 2017-11-09 Prüfverfahren und Prüfvorrichtung
DE102017126277.6 2017-11-09

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WO2019091961A1 true WO2019091961A1 (fr) 2019-05-16

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CN113251931A (zh) * 2021-07-07 2021-08-13 苏州维嘉科技股份有限公司 加工设备的零部件位置检测方法及零部件位置检测装置

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US20140260696A1 (en) * 2013-03-14 2014-09-18 Protedyne Corporation Laser triangulation for pipette tip position
EP2913107A1 (fr) 2014-02-21 2015-09-02 Waldorf Technik GmbH & Co. KG Procédé et dispositif d'évaluation d'une déformation de pointes de pipettes et/ou une erreur d'outil de moulage par injection

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FR1413261A (fr) 1964-09-30 1965-10-08 Nukem Gmbh Procédé et dispositif pour la mesure de la rectitude et des variations de diamètre de barres et de tubes
US5512247A (en) 1994-05-02 1996-04-30 Hoffmann-La Roche Inc. Apparatus for testing pipetting needle linearity in an automated analyzer
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Publication number Priority date Publication date Assignee Title
US20020174707A1 (en) * 2001-05-28 2002-11-28 Susumu Sawafuji Work center position determining method and apparatus
US20140260696A1 (en) * 2013-03-14 2014-09-18 Protedyne Corporation Laser triangulation for pipette tip position
EP2913107A1 (fr) 2014-02-21 2015-09-02 Waldorf Technik GmbH & Co. KG Procédé et dispositif d'évaluation d'une déformation de pointes de pipettes et/ou une erreur d'outil de moulage par injection

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113251931A (zh) * 2021-07-07 2021-08-13 苏州维嘉科技股份有限公司 加工设备的零部件位置检测方法及零部件位置检测装置
CN113251931B (zh) * 2021-07-07 2021-09-21 苏州维嘉科技股份有限公司 加工设备的零部件位置检测方法及零部件位置检测装置

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