WO2019043547A3 - 抗菌用水凝胶 - Google Patents

抗菌用水凝胶 Download PDF

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Publication number
WO2019043547A3
WO2019043547A3 PCT/IB2018/056475 IB2018056475W WO2019043547A3 WO 2019043547 A3 WO2019043547 A3 WO 2019043547A3 IB 2018056475 W IB2018056475 W IB 2018056475W WO 2019043547 A3 WO2019043547 A3 WO 2019043547A3
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WO
WIPO (PCT)
Prior art keywords
water
antibacterial
antibacterial hydrogel
polymer composition
soluble polymer
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Application number
PCT/IB2018/056475
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English (en)
French (fr)
Other versions
WO2019043547A2 (zh
Inventor
娄敬
林幸钰
何美乡
邓昭芳
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娄敬
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Publication date
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Publication of WO2019043547A2 publication Critical patent/WO2019043547A2/zh
Publication of WO2019043547A3 publication Critical patent/WO2019043547A3/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/20—Elemental chlorine; Inorganic compounds releasing chlorine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0004—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

一种抗菌用水凝胶，是由混合物所形成的水凝胶，该混合物包含：水溶性聚合物组合物、过氧化酶、二氧化氯及水，该水溶性聚合物组合物包括聚乙二醇及选自于聚乙烯醇及聚（：甲基：）丙烯酸中至少一者。本发明抗菌用水凝胶具有亲水性及抗菌性（例如杀菌或抑制细菌生长等），有助于皮肤伤口修复。
PCT/IB2018/056475 2017-08-28 2018-08-27 抗菌用水凝胶 WO2019043547A2 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TW106129168 2017-08-28
TW106129168A TWI644676B (zh) 2017-08-28 2017-08-28 Antibacterial hydrogel

Publications (2)

Publication Number Publication Date
WO2019043547A2 WO2019043547A2 (zh) 2019-03-07
WO2019043547A3 true WO2019043547A3 (zh) 2019-07-11

Family

ID=65431675

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2018/056475 WO2019043547A2 (zh) 2017-08-28 2018-08-27 抗菌用水凝胶

Country Status (3)

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CN (1) CN109420197B (zh)
TW (1) TWI644676B (zh)
WO (1) WO2019043547A2 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220307194A1 (en) * 2019-08-30 2022-09-29 Brandeis University Self-decontaminating, self-deodorizing textiles and surfaces and methods of making and using the same
CN114732942B (zh) * 2022-04-12 2023-04-21 兰州大学 一种二氧化氯缓释型液体创可贴及其制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1708281A (zh) * 2002-11-04 2005-12-14 沛瑞丹泰斯实验公司 口腔卫生系统及理疗方法
CN101194627A (zh) * 2006-12-08 2008-06-11 吴予奇 小空间消毒除异味缓释剂
CN101669518A (zh) * 2009-09-30 2010-03-17 北京欧凯纳斯科技有限公司 含二氧化氯的杀菌、抗病毒组合物
CN101810874A (zh) * 2009-12-15 2010-08-25 北京欧凯纳斯科技有限公司 一种缓释二氧化氯凝胶、其制备方法及其应用
CN103565828A (zh) * 2012-07-24 2014-02-12 殷豪章 一种二氧化氯凝胶及其制备方法
CN107286354A (zh) * 2016-03-30 2017-10-24 娄敬 水凝胶Chlorine Dioxide/PEG交联聚合链结物制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
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JP2003535165A (ja) * 2000-05-30 2003-11-25 ビリディス バイオテック インコーポレイテッド ポリユビキチン系ヒドロゲルとその用途
US8840918B2 (en) * 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US8512731B2 (en) * 2007-11-13 2013-08-20 Medtronic Minimed, Inc. Antimicrobial coatings for medical devices and methods for making and using them
CN101439206A (zh) * 2007-11-22 2009-05-27 郭倩 酶催化快速固化水凝胶的制备及其应用
KR20110030688A (ko) * 2008-07-15 2011-03-23 바스프 코포레이션 비세포독성 이산화염소 유체
KR101091028B1 (ko) * 2009-07-02 2011-12-09 아주대학교산학협력단 체내 주입형 하이드로젤 및 이의 생의학적 용도
CN102000021B (zh) * 2010-11-18 2012-06-27 毕小平 一种稳定性二氧化氯缓释凝胶制剂,其制备方法及其应用
CN106397645B (zh) * 2016-09-10 2018-10-23 上海大学 一种电化学聚合制备丙烯酸系水凝胶的方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1708281A (zh) * 2002-11-04 2005-12-14 沛瑞丹泰斯实验公司 口腔卫生系统及理疗方法
CN101194627A (zh) * 2006-12-08 2008-06-11 吴予奇 小空间消毒除异味缓释剂
CN101669518A (zh) * 2009-09-30 2010-03-17 北京欧凯纳斯科技有限公司 含二氧化氯的杀菌、抗病毒组合物
CN101810874A (zh) * 2009-12-15 2010-08-25 北京欧凯纳斯科技有限公司 一种缓释二氧化氯凝胶、其制备方法及其应用
CN103565828A (zh) * 2012-07-24 2014-02-12 殷豪章 一种二氧化氯凝胶及其制备方法
CN107286354A (zh) * 2016-03-30 2017-10-24 娄敬 水凝胶Chlorine Dioxide/PEG交联聚合链结物制备方法

Also Published As

Publication number Publication date
WO2019043547A2 (zh) 2019-03-07
TWI644676B (zh) 2018-12-21
TW201912165A (zh) 2019-04-01
CN109420197B (zh) 2021-09-21
CN109420197A (zh) 2019-03-05

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