WO2018149290A1 - Medicinal liquor for treating bone diseases - Google Patents

Medicinal liquor for treating bone diseases Download PDF

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Publication number
WO2018149290A1
WO2018149290A1 PCT/CN2018/074519 CN2018074519W WO2018149290A1 WO 2018149290 A1 WO2018149290 A1 WO 2018149290A1 CN 2018074519 W CN2018074519 W CN 2018074519W WO 2018149290 A1 WO2018149290 A1 WO 2018149290A1
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parts
wine
bone diseases
raw materials
medicinal
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PCT/CN2018/074519
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French (fr)
Chinese (zh)
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卢异奇
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卢异奇
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A61K36/126—Drynaria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254—Acanthopanax or Eleutherococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487—Psoralea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884—Arisaema, e.g. Jack in the pulpit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Definitions

  • the invention relates to the technical field of medicine, in particular to a medicinal liquor for treating bone diseases.
  • Bone is a hard organ that makes up vertebrate animals. Its function is to exercise, support and protect the body.
  • Osteopathic diseases generally include: rheumatoid arthritis, rheumatoid arthritis, degenerative arthritis, ankylosing spondylitis, cervical spondylosis, lumbar spondylosis, frozen shoulder, bone hyperplasia, femoral head necrosis, osteomyelitis, postpartum wind, etc. .
  • the treatment of bone diseases includes surgical treatment and medical treatment. If treated by surgery, the patient needs to withstand greater physical and psychological stress. Generally, surgery is often performed in the event of a last resort. Inadvertent surgery can also cause disability. Regardless of the cause, once suffering from bone disease, it is necessary to seek early detection and early diagnosis. The use of traditional Chinese medicine surgery has already cured many patients with bone diseases.
  • the invention provides a medicinal liquor for treating bone diseases, which is prepared by mixing raw materials arranged in the following parts by weight with wine; the raw materials and wine and the parts thereof are: 3-8 parts of Gentiana 6-12 parts of Eucommia, 10-20 parts of Acanthopanax, 10-15 parts of Araceae, 12-18 parts of honeysuckle, 8-18 parts of deer grass, 6-9 parts of sea breeze, 5-10 parts of hematoxylin, frankincense 15-20 parts, Wujiapi 15-20 parts, anti-self 5-8 parts, aconite 3-9 parts, bone broken 11-20 parts, psoralen 9-16 parts, Codonopsis 3-6 parts, Polygonum cuspidatum 5 -10 parts, 8-12 parts of blood, 1-6 parts of white peony, 6-12 parts of silkworm, 3-8 parts of angelica, 10-15 parts of Chuanxiong, 2-8 parts of Polygonum multiflorum, 1000-3000 parts of wine.
  • the raw materials and the wine and the parts thereof are: 5 parts of Gentiana, 10 parts of Eucommia, 15 parts of Acanthopanax, 13 parts of Araceae, 15 parts of honeysuckle, 11 parts of deer, and 7 Serve, 8 parts of hemat, 18 parts of frankincense, 19 parts of Wujiapi, 6 parts of anti-self, 6 parts of aconite, 16 parts of broken bones, 14 parts of psoralen, 5 parts of Codonopsis, 7 parts of Polygonum cuspidatum, 10 parts of blood 4 parts of white peony, 8 parts of silkworm, 6 parts of angelica, 12 parts of Chuanxiong, 5 parts of Polygonum multiflorum, 2000 parts of wine.
  • the wine is yellow wine, rice wine or fruit wine.
  • the wine has a degree of from 20° to 30°.
  • the method for preparing the medicinal wine comprises the following steps:
  • step (1) Put the wine and the raw materials in step (1) into the bottle and let it stand for 8-12 days.
  • the liquid filtered through the gauze is the medicinal liquor, and the dregs are retained in the bottle.
  • the invention provides the medicinal liquor for treating bone disease and the preparation method thereof, wherein the raw material component is reasonable, the formula is scientific, the raw materials are common and easy to obtain, the production and preparation process is simple, the cure rate is high, and the treatment process is painless, non-toxic and has no side effects. It is convenient and safe, and has good curative effect on treating various bone diseases such as femoral head necrosis and osteomyelitis.
  • Embodiment 1 is a diagrammatic representation of Embodiment 1:
  • a medicinal wine for treating bone diseases which is prepared by mixing raw materials arranged in the following parts by weight with wine.
  • the raw materials and wine and the parts thereof are: 3 parts of Gentiana, 6 parts of Eucommia, 10 parts of Acanthopanax, 10 parts of Araceae, 12 parts of honeysuckle, 8 parts of deer, 8 parts of sea breeze, 5 parts of Sumu, 15 parts of frankincense, 15 parts of Wujiapi, 5 parts of anti-five, 3 parts of aconite, 11 parts of broken bones, 9 parts of psoralen, 3 parts of Codonopsis, 5 parts of Polygonum cuspidatum, 8 parts of blood, 1 part of white peony, silkworm 6 parts, 3 parts of angelica, 10 parts of Chuanxiong, 2 parts of Polygonum multiflorum, 1000 parts of wine.
  • the preparation method of the medicinal wine comprises the following steps:
  • step (1) Put the wine and the raw materials in step (1) into the bottle and let it stand for 8-12 days.
  • the liquid filtered through the gauze is the medicinal liquor, and the dregs are retained in the bottle.
  • the wine is rice wine, rice wine or fruit wine, and is preferably yellow wine.
  • the wine has a degree of from 20 to 30, and preferably 20.
  • Rice wine is also used as an intermediary to operate the active ingredients to the affected area of the patient.
  • the patient can quickly absorb the medicinal liquor, penetrate the whole body meridian including bone joints, participate in human hemoglobin synthesis, repair bone marrow cells, promote hematopoiesis, accelerate blood circulation, and remove siltation. Timely relief, convergence of pain, recovery of human function, showing the exact effect.
  • Patients with ankylosing spondylitis can gradually relieve pain within one month after taking it. Due to long-term ankylosing spondylitis and physical deformation, patients with severe hunchback can also stand up for normal life and work.
  • the time for treating lumbar and cervical diseases is 10 days to 20 days
  • the treatment for ankylosing spondylitis is 20 days to 40 days
  • the time for treatment of femoral head necrosis is 30 days to 100 days.
  • the time for treatment of osteomyelitis is longer.
  • Embodiment 2 is a diagrammatic representation of Embodiment 1:
  • the main difference between the present embodiment and the above embodiments is that the raw materials and the wine and the parts thereof are: 5 parts of Gentiana, 10 parts of Eucommia, 15 parts of Acanthopanax, 13 parts of Araceae, 15 parts of honeysuckle, and 11 parts of deer.
  • the wine is rice wine, rice wine or fruit wine, and is preferably rice wine.
  • the wine has a degree of from 20 to 30, and preferably 25.
  • Embodiment 3 is a diagrammatic representation of Embodiment 3
  • the main difference between the present embodiment and the above embodiments is that the raw materials and the wine and the parts thereof are: 8 parts of Gentiana, 12 parts of Eucommia, 20 parts of Acanthopanax, 15 parts of Araceae, 18 parts of honeysuckle, and 18 pieces of deer and grass.
  • the wine is rice wine, rice wine or fruit wine, and is preferably fruit wine, and is further preferably mulberry wine.
  • the wine has a degree of from 20 to 30, and preferably 30.
  • the experimental method was to select 30 patients with femoral head necrosis, including 15 female patients and 15 male patients. They were randomly divided into two groups, and the market-selling common drugs with the same effect were selected for experimentation, and the effects of the drugs after use were compared.
  • the comparative standard is the efficacy standard for femoral head necrosis in "Diagnostic Efficacy Standards for TCM Diseases", as follows:
  • Cure walking without flaws, no pain in the hip joint, no shortening of the lower limbs, complete or basic recovery, X-ray film femoral head dead bone collapse, osteonecrosis and bone hyperplasia almost disappeared.
  • the medicinal liquor for treating bone diseases provided by the invention can not only treat femoral head necrosis, but also treat various bone diseases such as cervical spondylosis, lumbar spondylosis, frozen shoulder, bone hyperplasia, femoral head necrosis and osteomyelitis.
  • the medicinal liquor for treating bone diseases provided by the present invention has already cured 162 patients with bone diseases, and will not be enumerated here.

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  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Alternative & Traditional Medicine (AREA)
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Abstract

Disclosed is a medicinal liquor for treating bone diseases, which is made by mixing and soaking the following raw materials with/in liquor: Gentiana macrophylla, Eucommia ulmoides, Radix Acanthopanacis Senticosi, Rhizoma arisaematis, honeysuckle, herb pyrolae, Caulis Piperis Futokadssurae, hematoxylon, frankincense, Cortex acanthopanacis, Radix Stephaniae Tetrandrae, Radix Aconiti Lateralis, Rhizoma Drynaria, Fructus Psoraleae, Radix Codonopsis, Polygonum Cuspidatum, Resina Draconis, Radix Angelicae Dahuricae, silkworm feces, Angelica Sinensis, Rhizoma Chuanxiong and Polygonum multiflorum. The medicinal liquor has a better therapeutic effect on various bone diseases such as femoral head necrosis and osteomyelitis.

Description

一种治疗骨病的药酒Medicated wine for treating bone disease 技术领域Technical field
本发明涉及医药技术领域，尤其涉及一种治疗骨病的药酒。The invention relates to the technical field of medicine, in particular to a medicinal liquor for treating bone diseases.
背景技术Background technique
人体共有206块骨骼，分为29块颅骨、51块躯干骨和126块四肢骨三个大部分。骨骼是组成脊椎动物的坚硬器官，功能是运动、支持和保护身体。The human body has a total of 206 bones, divided into 29 skulls, 51 trunk bones and 126 limb bones. Bone is a hard organ that makes up vertebrate animals. Its function is to exercise, support and protect the body.
骨骼是人体非常重要的身体部位，如果骨骼发生疾病的话，那么会对健康有很直接的威胁，另外严重的骨骼疾病还可能会对生命有很大的威胁。Bone is a very important part of the body. If the bones are ill, it will have a direct threat to health. In addition, serious bone diseases may pose a great threat to life.
骨病一般包括:风湿性关节炎、类风湿性关节炎、退行性关节炎、强直性脊柱炎、颈椎病、腰椎病、肩周炎、骨质增生、股骨头坏死、骨髓炎、产后风等。Osteopathic diseases generally include: rheumatoid arthritis, rheumatoid arthritis, degenerative arthritis, ankylosing spondylitis, cervical spondylosis, lumbar spondylosis, frozen shoulder, bone hyperplasia, femoral head necrosis, osteomyelitis, postpartum wind, etc. .
目前，骨病的治疗方法有手术治疗和药物治疗等。若通过手术治疗，患者需要承受较大的身体和心理压力，一般多在不得已的情况下进行手术治疗，手术不慎还会致残。无论何种病因，一旦患上骨病，要争取早发现早确诊，采用中医药免手术方法目前已经治愈了众多骨病患者。At present, the treatment of bone diseases includes surgical treatment and medical treatment. If treated by surgery, the patient needs to withstand greater physical and psychological stress. Generally, surgery is often performed in the event of a last resort. Inadvertent surgery can also cause disability. Regardless of the cause, once suffering from bone disease, it is necessary to seek early detection and early diagnosis. The use of traditional Chinese medicine surgery has already cured many patients with bone diseases.
发明内容Summary of the invention
本发明提供了一种治疗骨病的药酒，所述药酒由按下述重量份数配置的原料与酒混合泡制而成；所述原料与酒及其重量份数为：秦艽3-8份，杜仲6-12份，刺五加10-20份，天南星10-15份，金银花12-18份，鹿含草8-18份，海风藤6-9份，苏木5-10份，乳香15-20份，五加皮15-20份，防己5-8份，制附子3-9份，骨碎补11-20份，补骨脂9-16份，党参3-6份，虎杖5-10份，血竭8-12份，白芷1-6份，蚕沙6-12份，当归3-8份，川芎10-15份，何首乌2-8份，酒1000-3000份。The invention provides a medicinal liquor for treating bone diseases, which is prepared by mixing raw materials arranged in the following parts by weight with wine; the raw materials and wine and the parts thereof are: 3-8 parts of Gentiana 6-12 parts of Eucommia, 10-20 parts of Acanthopanax, 10-15 parts of Araceae, 12-18 parts of honeysuckle, 8-18 parts of deer grass, 6-9 parts of sea breeze, 5-10 parts of hematoxylin, frankincense 15-20 parts, Wujiapi 15-20 parts, anti-self 5-8 parts, aconite 3-9 parts, bone broken 11-20 parts, psoralen 9-16 parts, Codonopsis 3-6 parts, Polygonum cuspidatum 5 -10 parts, 8-12 parts of blood, 1-6 parts of white peony, 6-12 parts of silkworm, 3-8 parts of angelica, 10-15 parts of Chuanxiong, 2-8 parts of Polygonum multiflorum, 1000-3000 parts of wine.
本发明的一些方案中，所述原料与酒及其重量份数为：秦艽5份，杜仲10份，刺五加15份，天南星13份，金银花15份，鹿含草11份，海风藤7份，苏木8份，乳香18份，五加皮19份，防己6份，制附子6份，骨碎补16份，补骨脂14份，党参5份，虎杖7份，血 竭10份，白芷4份，蚕沙8份，当归6份，川芎12份，何首乌5份，酒2000份。In some aspects of the present invention, the raw materials and the wine and the parts thereof are: 5 parts of Gentiana, 10 parts of Eucommia, 15 parts of Acanthopanax, 13 parts of Araceae, 15 parts of honeysuckle, 11 parts of deer, and 7 Serve, 8 parts of hemat, 18 parts of frankincense, 19 parts of Wujiapi, 6 parts of anti-self, 6 parts of aconite, 16 parts of broken bones, 14 parts of psoralen, 5 parts of Codonopsis, 7 parts of Polygonum cuspidatum, 10 parts of blood 4 parts of white peony, 8 parts of silkworm, 6 parts of angelica, 12 parts of Chuanxiong, 5 parts of Polygonum multiflorum, 2000 parts of wine.
本发明的一些方案中，所述酒为黄酒、米酒或者果酒。In some aspects of the invention, the wine is yellow wine, rice wine or fruit wine.
本发明的一些方案中，所述酒的度数为20°-30°。In some aspects of the invention, the wine has a degree of from 20° to 30°.
本发明的一些方案中，所述药酒的制备方法包括如下步骤：In some aspects of the present invention, the method for preparing the medicinal wine comprises the following steps:
(1)精选性能优质的原料备用；(1) Selecting high-quality raw materials for use;
(2)将酒和步骤(1)中的原料共同放入酒瓶中，静置8-12天，经纱布过滤出的液体为药酒，药渣滞留在酒瓶中。(2) Put the wine and the raw materials in step (1) into the bottle and let it stand for 8-12 days. The liquid filtered through the gauze is the medicinal liquor, and the dregs are retained in the bottle.
技术效果Technical effect
本发明所提供的治疗骨病的药酒及其制备方法，其原料组分合理，配方科学，原料常见易得，生产制备过程简单，治愈率高，治疗过程中无痛、无毒、无副作用，方便安全，对治疗各种骨病例如股骨头坏死、骨髓炎等具有较好的疗效。The invention provides the medicinal liquor for treating bone disease and the preparation method thereof, wherein the raw material component is reasonable, the formula is scientific, the raw materials are common and easy to obtain, the production and preparation process is simple, the cure rate is high, and the treatment process is painless, non-toxic and has no side effects. It is convenient and safe, and has good curative effect on treating various bone diseases such as femoral head necrosis and osteomyelitis.
具体实施方式detailed description
为了更好的理解本发明的内容，下面结合具体实施例来做进一步的说明，但具体的实施方式并不是对本发明的内容所做的限制。For a better understanding of the content of the present invention, the following detailed description is made in conjunction with the specific embodiments, but the specific embodiments are not limited to the content of the present invention.
实施例一：Embodiment 1:
一种治疗骨病的药酒，所述药酒由按下述重量份数配置的原料与酒混合泡制而成。A medicinal wine for treating bone diseases, which is prepared by mixing raw materials arranged in the following parts by weight with wine.
所述原料与酒及其重量份数为：秦艽3份，杜仲6份，刺五加10份，天南星10份，金银花12份，鹿含草8份，海风藤6份，苏木5份，乳香15份，五加皮15份，防己5份，制附子3份，骨碎补11份，补骨脂9份，党参3份，虎杖5份，血竭8份，白芷1份，蚕沙6份，当归3份，川芎10份，何首乌2份，酒1000份。The raw materials and wine and the parts thereof are: 3 parts of Gentiana, 6 parts of Eucommia, 10 parts of Acanthopanax, 10 parts of Araceae, 12 parts of honeysuckle, 8 parts of deer, 8 parts of sea breeze, 5 parts of Sumu, 15 parts of frankincense, 15 parts of Wujiapi, 5 parts of anti-five, 3 parts of aconite, 11 parts of broken bones, 9 parts of psoralen, 3 parts of Codonopsis, 5 parts of Polygonum cuspidatum, 8 parts of blood, 1 part of white peony, silkworm 6 parts, 3 parts of angelica, 10 parts of Chuanxiong, 2 parts of Polygonum multiflorum, 1000 parts of wine.
所述药酒的制备方法包括如下步骤：The preparation method of the medicinal wine comprises the following steps:
(1)精选性能优质的原料备用；(1) Selecting high-quality raw materials for use;
(2)将酒和步骤(1)中的原料共同放入酒瓶中，静置8-12天，经纱布过滤出的液体为药酒，药渣滞留在酒瓶中。(2) Put the wine and the raw materials in step (1) into the bottle and let it stand for 8-12 days. The liquid filtered through the gauze is the medicinal liquor, and the dregs are retained in the bottle.
所述酒为黄酒、米酒或者果酒，并优选为黄酒。所述酒的度数为20°-30°，并优选为20°。The wine is rice wine, rice wine or fruit wine, and is preferably yellow wine. The wine has a degree of from 20 to 30, and preferably 20.
用黄酒泡制各种原料，能够使各种原料中的有效的活性成份释放出来。黄酒又作为中介体来营运活性成份至患者的患处，患者服用该 药酒后能迅速吸收，贯通全身经络包括骨骼关节，参与人体血红蛋白合成，修复骨髓细胞，促进造血功能，加速血液循环，清除淤积，及时缓解、收敛其疼痛，恢复人体机能，显现出确切的疗效。The use of yellow wine to brew various raw materials enables the release of effective active ingredients in various raw materials. Rice wine is also used as an intermediary to operate the active ingredients to the affected area of the patient. The patient can quickly absorb the medicinal liquor, penetrate the whole body meridian including bone joints, participate in human hemoglobin synthesis, repair bone marrow cells, promote hematopoiesis, accelerate blood circulation, and remove siltation. Timely relief, convergence of pain, recovery of human function, showing the exact effect.
病情较为严重的患者，服用该药酒的见效最快，一般情况下，在服用2-3天后，就明显感觉到疼痛感有所缓解，逐渐至基本消除疼痛并不再复发。In patients with more serious illness, taking the medicinal liquor is the quickest. Under normal circumstances, after taking 2-3 days, the pain is obviously relieved, and the pain is gradually eliminated and the recurrence is no longer repeated.
如果是腰椎间盘突出或者坐骨神经患者，其下肢酸痛，麻痹瘫痪在床的重症患者，服用10天左右就能活动起床，面色转变有光泽，一个月后就能正常生活工作，并且不易复发。If it is a patient with lumbar disc herniation or sciatic nerve, the lower limbs are sore, and the critically ill patients who are paralyzed in bed can get up and get up after taking it for about 10 days. The complexion is shiny and shiny. After one month, they can work normally and are not easy to relapse.
强直性脊柱炎患者在服用后一个月内可以逐步缓解疼痛感，由于长期患强直性脊柱炎而身体变形，严重驼背的患者也能挺起腰杆正常生活与工作。Patients with ankylosing spondylitis can gradually relieve pain within one month after taking it. Due to long-term ankylosing spondylitis and physical deformation, patients with severe hunchback can also stand up for normal life and work.
治疗腰椎和颈椎疾病的时间为10天-20天，治疗强直性脊柱炎时间在20天-40天，治疗股骨头坏死时间在30天-100天，治疗骨髓炎的时间更长。The time for treating lumbar and cervical diseases is 10 days to 20 days, the treatment for ankylosing spondylitis is 20 days to 40 days, and the time for treatment of femoral head necrosis is 30 days to 100 days. The time for treatment of osteomyelitis is longer.
实施例二：Embodiment 2:
本实施例与上述实施例的主要区别在于：所述原料与酒及其重量份数为：秦艽5份，杜仲10份，刺五加15份，天南星13份，金银花15份，鹿含草11份，海风藤7份，苏木8份，乳香18份，五加皮19份，防己6份，制附子6份，骨碎补16份，补骨脂14份，党参5份，虎杖7份，血竭10份，白芷4份，蚕沙8份，当归6份，川芎12份，何首乌5份，酒2000份。The main difference between the present embodiment and the above embodiments is that the raw materials and the wine and the parts thereof are: 5 parts of Gentiana, 10 parts of Eucommia, 15 parts of Acanthopanax, 13 parts of Araceae, 15 parts of honeysuckle, and 11 parts of deer. 4 parts of sea buckthorn, 8 pieces of hematoxylin, 18 parts of frankincense, 19 parts of Wujiapi, 6 parts of anti-self, 6 parts of aconite, 16 parts of broken bones, 14 parts of psoralen, 5 parts of Codonopsis, 7 parts of Polygonum cuspidatum 10 parts of blood, 4 parts of white peony, 8 parts of silkworm, 6 parts of angelica, 12 parts of Chuanxiong, 5 parts of Polygonum multiflorum, 2000 parts of wine.
所述酒为黄酒、米酒或者果酒，并优选为米酒。所述酒的度数为20°-30°，并优选为25°。The wine is rice wine, rice wine or fruit wine, and is preferably rice wine. The wine has a degree of from 20 to 30, and preferably 25.
实施例三：Embodiment 3:
本实施例与上述实施例的主要区别在于：所述原料与酒及其重量份数为：秦艽8份，杜仲12份，刺五加20份，天南星15份，金银花18份，鹿含草18份，海风藤9份，苏木10份，乳香20份，五加皮20份，防己8份，制附子9份，骨碎补20份，补骨脂16份，党参6份，虎杖10份，血竭12份，白芷6份，蚕沙12份，当归8份，川芎15份，何首乌8份，酒3000份。The main difference between the present embodiment and the above embodiments is that the raw materials and the wine and the parts thereof are: 8 parts of Gentiana, 12 parts of Eucommia, 20 parts of Acanthopanax, 15 parts of Araceae, 18 parts of honeysuckle, and 18 pieces of deer and grass. 9 parts of sea breeze, 10 pieces of hematoxylin, 10 parts of frankincense, 20 parts of Wujiapi, 8 parts of anti-self, 9 parts of aconite, 20 parts of broken bones, 16 parts of psoralen, 6 parts of Codonopsis, 10 parts of Polygonum cuspidatum 12 parts of blood, 6 parts of white peony, 12 parts of silkworm, 8 parts of angelica, 15 parts of Chuanxiong, 8 parts of Polygonum multiflorum, 3000 parts of wine.
所述酒为黄酒、米酒或者果酒，并优选为果酒，并进一步优选为 桑葚酒。所述酒的度数为20°-30°，并优选为30°。The wine is rice wine, rice wine or fruit wine, and is preferably fruit wine, and is further preferably mulberry wine. The wine has a degree of from 20 to 30, and preferably 30.
为检验本发明的治疗效果，进行了以下实验。实验方法为：选取30个股骨头坏死的患者，包括15名女性患者和15名男性患者。随机分为两组，选取市面销售同等作用普通药品进行实验，对用药后的使用效果进行比较。In order to examine the therapeutic effects of the present invention, the following experiment was conducted. The experimental method was to select 30 patients with femoral head necrosis, including 15 female patients and 15 male patients. They were randomly divided into two groups, and the market-selling common drugs with the same effect were selected for experimentation, and the effects of the drugs after use were compared.
比较标准为《中医病症诊断疗效标准》中关于股骨头坏死的疗效标准，具体如下：The comparative standard is the efficacy standard for femoral head necrosis in "Diagnostic Efficacy Standards for TCM Diseases", as follows:
治愈：行走无跛行，髋关节无疼痛，下肢无短缩，功能完全或基本恢复，X线片股骨头死骨区塌陷、骨坏死及骨增生硬化现象基本消失。Cure: walking without flaws, no pain in the hip joint, no shortening of the lower limbs, complete or basic recovery, X-ray film femoral head dead bone collapse, osteonecrosis and bone hyperplasia almost disappeared.
好转：症状减轻，髋关节活动功能改善，下肢短缩在1厘米左右，X线片股骨头变大或扁平，但骨坏死及骨增生硬化现象有改善。Better: Symptoms are alleviated, hip function is improved, lower limb shortening is about 1 cm, and the femoral head of the X-ray film becomes larger or flat, but osteonecrosis and osteoproliferative hardening are improved.
未愈：症状无改善，X线片征象无改变。Unhealed: no improvement in symptoms, no change in X-ray signs.
经过3个疗程，时间为30天的治疗，治疗结果如下：After 3 courses of treatment, the time is 30 days of treatment, the treatment results are as follows:
Figure PCTCN2018074519-appb-000001
Figure PCTCN2018074519-appb-000001
应用实例：Applications:
1、余XX，男50岁，股骨头坏死，经服用本药酒后，骨坏死及骨增生硬化现象有改善，功能完全或基本恢复。1, Yu XX, male 50 years old, femoral head necrosis, after taking this medicine, osteonecrosis and bone hyperplasia have improved, and the function is completely or basically restored.
2、刘X，男，42岁，一年前骨小梁部分消失，囊状改变，骨质硬化，经服用本药酒后，骨坏死及骨增生硬化现象基本消失。2, Liu X, male, 42 years old, a part of the trabecular bone disappeared a year ago, cystic changes, osteosclerosis, after taking this medicine, osteonecrosis and bone hyperplasia almost disappeared.
3、李XX，女，34岁，半个月前股骨头扁平，关节间隙狭窄或消失，囊状改变明显，骨质硬化面积较大，股骨头软骨完全断裂。经服用本药酒后，骨坏死及骨增生硬化现象基本消失。3, Li XX, female, 34 years old, half a month ago, the femoral head is flat, the joint space is narrow or disappear, the cystic changes are obvious, the osteosclerosis area is larger, and the femoral head cartilage is completely broken. After taking this medicine, the phenomenon of osteonecrosis and osteoporosis hardening basically disappeared.
当然，本发明提供的治疗骨病的药酒不仅可治疗股骨头坏死，也可治疗颈椎病、腰椎病、肩周炎、骨质增生、股骨头坏死、骨髓炎等各种骨病。Of course, the medicinal liquor for treating bone diseases provided by the invention can not only treat femoral head necrosis, but also treat various bone diseases such as cervical spondylosis, lumbar spondylosis, frozen shoulder, bone hyperplasia, femoral head necrosis and osteomyelitis.
本发明提供的治疗骨病的药酒目前已经治愈162名骨病患者，此处不作一一列举。The medicinal liquor for treating bone diseases provided by the present invention has already cured 162 patients with bone diseases, and will not be enumerated here.

Claims (5)

  1. 一种治疗骨病的药酒，其特征在于，所述药酒由按下述重量份数配置的原料与酒混合泡制而成；A medicinal wine for treating bone diseases, characterized in that the medicinal wine is made by mixing raw materials arranged in the following parts by weight with wine;
    所述原料与酒及其重量份数为：秦艽3-8份，杜仲6-12份，刺五加10-20份，天南星10-15份，金银花12-18份，鹿含草8-18份，海风藤6-9份，苏木5-10份，乳香15-20份，五加皮15-20份，防己5-8份，制附子3-9份，骨碎补11-20份，补骨脂9-16份，党参3-6份，虎杖5-10份，血竭8-12份，白芷1-6份，蚕沙6-12份，当归3-8份，川芎10-15份，何首乌2-8份，酒1000-3000份。The raw materials and wine and the parts thereof are: 3-8 parts of Gentiana, 6-12 parts of Eucommia, 10-20 parts of Acanthopanax, 10-15 parts of Araceae, 12-18 parts of honeysuckle, and 8-18 of deer grass 4-9 parts of sea buckthorn, 5-10 parts of hematoxylin, 15-20 parts of frankincense, 15-20 parts of Wujiapi, 5-8 parts of anti-fever, 3-9 parts of aconite, 11-20 parts of broken bones 9-16 parts of psoralen, 3-6 parts of Codonopsis pilosula, 5-10 parts of Polygonum cuspidatum, 8-12 parts of blood, 1-6 parts of white peony, 6-12 parts of silkworm, 3-8 parts of angelica, Chuanxiong 10- 15 servings, 2-8 copies of Polygonum multiflorum, 1000-3000 servings of wine.
  2. 根据权利要求1所述的治疗骨病的药酒，其特征在于，所述原料与酒及其重量份数为：秦艽5份，杜仲10份，刺五加15份，天南星13份，金银花15份，鹿含草11份，海风藤7份，苏木8份，乳香18份，五加皮19份，防己6份，制附子6份，骨碎补16份，补骨脂14份，党参5份，虎杖7份，血竭10份，白芷4份，蚕沙8份，当归6份，川芎12份，何首乌5份，酒2000份。The medicinal liquor for treating bone diseases according to claim 1, wherein the raw materials and the wine and the parts thereof are: 5 parts of Gentiana, 10 parts of Eucommia, 15 parts of Acanthopanax, 13 parts of Araceae, 15 parts of honeysuckle. 11 deer with grass, 7 with sea breeze, 8 with hematoxylin, 18 with frankincense, 19 with five plus skin, 6 with anti-self, 6 with aconite, 16 with bone-breaking, 14 with psoralen, and codonopsis 5 4 parts of Polygonum cuspidatum, 10 parts of blood, 4 parts of white peony, 8 parts of silkworm, 6 parts of angelica, 12 parts of Chuanxiong, 5 parts of Polygonum multiflorum, 2000 parts of wine.
  3. 根据权利要求2所述的治疗骨病的药酒，其特征在于，所述酒为黄酒、米酒或者果酒。The medicinal wine for treating bone diseases according to claim 2, wherein the wine is rice wine, rice wine or fruit wine.
  4. 根据权利要求3所述的治疗骨病的药酒，其特征在于，所述酒的度数为20°-30°。The medicinal wine for treating bone diseases according to claim 3, wherein the wine has a degree of from 20 to 30.
  5. 根据权利要求1-4中任一项所述的治疗骨病的药酒，其特征在于，所述药酒的制备方法包括如下步骤：The medicinal liquor for treating bone diseases according to any one of claims 1 to 4, wherein the preparation method of the medicinal liquor comprises the following steps:
    (1)精选性能优质的原料备用；(1) Selecting high-quality raw materials for use;
    (2)将酒和步骤(1)中的原料共同放入酒瓶中，静置8-12天，经纱布过滤出的液体为药酒，药渣滞留在酒瓶中。(2) Put the wine and the raw materials in step (1) into the bottle and let it stand for 8-12 days. The liquid filtered through the gauze is the medicinal liquor, and the dregs are retained in the bottle.
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