WO2018135912A3 - 커큐민이 포집된 진세노사이드 및 인지질 기반 지질나노입자를 유효성분으로 함유하는 헬리코박터 파이로리 감염의 예방 또는 치료용 조성물 - Google Patents

커큐민이 포집된 진세노사이드 및 인지질 기반 지질나노입자를 유효성분으로 함유하는 헬리코박터 파이로리 감염의 예방 또는 치료용 조성물 Download PDF

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WO2018135912A3
WO2018135912A3 PCT/KR2018/000936 KR2018000936W WO2018135912A3 WO 2018135912 A3 WO2018135912 A3 WO 2018135912A3 KR 2018000936 W KR2018000936 W KR 2018000936W WO 2018135912 A3 WO2018135912 A3 WO 2018135912A3
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WIPO (PCT)
Prior art keywords
curcumin
captured
helicobacter pylori
ginsenoside
phospholipid
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PCT/KR2018/000936
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English (en)
French (fr)
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WO2018135912A2 (ko
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유봉규
아제이비자야쿠마르
정광원
정준원
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가천대학교 산학협력단
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Publication of WO2018135912A2 publication Critical patent/WO2018135912A2/ko
Publication of WO2018135912A3 publication Critical patent/WO2018135912A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/20—Natural extracts
    • A23V2250/21—Plant extracts
    • A23V2250/2112—Curcumin, turmeric

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 커큐민이 포집된 진세노사이드 및 인지질 기반 지질나노입자를 유효성분으로 함유하는 헬리코박터 파이로리 감염의 예방 또는 치료용 조성물에 관한 것이다. 구체적으로, 본 발명의 커큐민이 포집된 진세노사이드 및 인지질 기반 지질나노입자는 포집된 커큐민의 용해도 및 안정성을 향상시키며, 헬리코박터 파이로리에 대한 항균력이 우수함으로써, 헬리코박터 파이로리의 감염을 치료하는데 유용하게 사용될 수 있다.
PCT/KR2018/000936 2017-01-20 2018-01-22 커큐민이 포집된 진세노사이드 및 인지질 기반 지질나노입자를 유효성분으로 함유하는 헬리코박터 파이로리 감염의 예방 또는 치료용 조성물 WO2018135912A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170009678A KR101948407B1 (ko) 2017-01-20 2017-01-20 커큐민이 포집된 진세노사이드 및 인지질 기반 지질나노입자를 유효성분으로 함유하는 헬리코박터 파이로리 감염의 예방 또는 치료용 조성물
KR10-2017-0009678 2017-01-20

Publications (2)

Publication Number Publication Date
WO2018135912A2 WO2018135912A2 (ko) 2018-07-26
WO2018135912A3 true WO2018135912A3 (ko) 2019-01-24

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PCT/KR2018/000936 WO2018135912A2 (ko) 2017-01-20 2018-01-22 커큐민이 포집된 진세노사이드 및 인지질 기반 지질나노입자를 유효성분으로 함유하는 헬리코박터 파이로리 감염의 예방 또는 치료용 조성물

Country Status (2)

Country Link
KR (1) KR101948407B1 (ko)
WO (1) WO2018135912A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109045064B (zh) * 2018-08-02 2020-03-31 山东大学 一种岩藻多糖与姜黄素的固体分散体的制备方法及其应用
KR102166253B1 (ko) * 2018-10-22 2020-10-16 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 지페노사이드 75(Gypenoside LXXV)를 유효성분으로 포함하는 상처 치유용 조성물
KR102169710B1 (ko) * 2020-01-08 2020-10-26 제주대학교 산학협력단 커큐민 나노스피어, 그 제조방법 및 이의 용도

Citations (4)

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KR19990030700A (ko) * 1997-10-02 1999-05-06 이영무 장기 안정성이 우수한 인지질 나노캡슐의 제조방법
KR20030094523A (ko) * 2002-05-27 2003-12-18 주식회사 태평양 인삼사포닌 대사 산물을 유효 성분으로 한 미세 유화 입자 및 그 제조방법, 이를 함유한 피부 노화방지용 화장료 조성물
US20120058208A1 (en) * 2010-09-04 2012-03-08 Synthite Industries Ltd. Synergistic Composition for Enhancing Bioavailability of Curcumin
CN104997655A (zh) * 2015-08-17 2015-10-28 杭州华胄科技有限公司 含姜黄素的具有抗幽门螺杆菌功效的口腔护理产品

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CN101530389B (zh) 2008-03-11 2012-02-15 沈阳市万嘉生物技术研究所 人参皂苷Rg3磷脂复合物及其制备方法

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KR20030094523A (ko) * 2002-05-27 2003-12-18 주식회사 태평양 인삼사포닌 대사 산물을 유효 성분으로 한 미세 유화 입자 및 그 제조방법, 이를 함유한 피부 노화방지용 화장료 조성물
US20120058208A1 (en) * 2010-09-04 2012-03-08 Synthite Industries Ltd. Synergistic Composition for Enhancing Bioavailability of Curcumin
CN104997655A (zh) * 2015-08-17 2015-10-28 杭州华胄科技有限公司 含姜黄素的具有抗幽门螺杆菌功效的口腔护理产品

Non-Patent Citations (3)

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WANG ET AL.: "Enhanced Bioavailability and Efficiency of Curcumin for the Treatment of Asthma by Its Formulation in Solid Lipid Nanoparticles", INTERNATIONAL JOURNAL OF NANOMEDICINE, vol. 7, 2012, pages 3667 - 3677, XP055563116 *
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Publication number Publication date
WO2018135912A2 (ko) 2018-07-26
KR20180085947A (ko) 2018-07-30
KR101948407B1 (ko) 2019-02-14

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