MX2022015601A - Compuesto para el tratamiento de infecciones coronavirales. - Google Patents
Compuesto para el tratamiento de infecciones coronavirales.Info
- Publication number
- MX2022015601A MX2022015601A MX2022015601A MX2022015601A MX2022015601A MX 2022015601 A MX2022015601 A MX 2022015601A MX 2022015601 A MX2022015601 A MX 2022015601A MX 2022015601 A MX2022015601 A MX 2022015601A MX 2022015601 A MX2022015601 A MX 2022015601A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- compound
- coronaviral
- infections
- coronaviral infections
- Prior art date
Links
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- YSZIOXAEADAJLX-UHFFFAOYSA-N phthalazine-1,4-dione Chemical compound C1=CC=C2C(=O)N=NC(=O)C2=C1 YSZIOXAEADAJLX-UHFFFAOYSA-N 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente solicitud se refiere al uso de una ftalazindiona en la prevención o el tratamiento de infecciones coronavirales. Se divulgan composiciones farmacéuticas, combinaciones y técnicas de formulación ventajosas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20000212 | 2020-06-10 | ||
EP20000366.3A EP3981405A1 (en) | 2020-10-08 | 2020-10-08 | Compound for the treatment of coronaviral infections |
PCT/EP2021/000071 WO2021249667A1 (en) | 2020-06-10 | 2021-06-09 | Compound for the treatment of coronaviral infections |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022015601A true MX2022015601A (es) | 2023-01-30 |
Family
ID=76444360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022015601A MX2022015601A (es) | 2020-06-10 | 2021-06-09 | Compuesto para el tratamiento de infecciones coronavirales. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20230218614A1 (es) |
EP (1) | EP4164651A1 (es) |
JP (1) | JP2023529022A (es) |
KR (1) | KR20230027150A (es) |
CN (1) | CN116075306A (es) |
AU (1) | AU2021288757A1 (es) |
BR (1) | BR112022025134A2 (es) |
CA (1) | CA3182022A1 (es) |
IL (1) | IL298899A (es) |
MX (1) | MX2022015601A (es) |
WO (1) | WO2021249667A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20240075029A1 (en) * | 2020-12-02 | 2024-03-07 | Metriopharm Ag | Luminol for the prophylaxis and the treatment of sequelae of a sars-cov-2 infection |
EP4193994A1 (en) * | 2021-12-08 | 2023-06-14 | MetrioPharm AG | Combination of 5-amino-2,3-dihydro-1,4-phtalazinedione and a 6'-methoxycinchonan-9-ol for use in the treatment of coronaviral infections |
EP4209219A1 (en) * | 2022-01-07 | 2023-07-12 | MetrioPharm AG | Combination of budesonide and 5-amino-2,3-dihydro-1,4-phtalazinedione |
WO2023131579A1 (en) * | 2022-01-07 | 2023-07-13 | Metriopharm Ag | Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of congenital muscular dystrophies |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9011833D0 (en) | 1990-05-25 | 1990-07-18 | Collins Mary K L | Inhibition of viral infection |
US6953799B1 (en) | 2002-10-30 | 2005-10-11 | Bach Pharma, Inc. | Modulation of cell fates and activities by diketo phthalazines |
US7326690B2 (en) * | 2002-10-30 | 2008-02-05 | Bach Pharma, Inc. | Modulation of cell fates and activities by phthalazinediones |
ITMI20052036A1 (it) | 2005-10-26 | 2007-04-27 | Professional Dietetics Srl | Composizioni farmaceutiche oftalmiche a base di amminoacidi e sodio ialuronato |
PL231885B1 (pl) | 2009-01-16 | 2019-04-30 | Abidopharma Spolka Z Ograniczona Odpowiedzialnoscia | Sposób wytwarzania soli 5-amino-2,3-dihydroftalazyno-1,4-di onu z metalami alkalicznymi, ich kompozycje farmaceutyczne i ich zastosowanie |
CA2791327C (en) | 2010-03-01 | 2018-10-30 | Metriopharm Ag | Crystalline forms of 5-amino-2,3-dihydrophthalazine-1,4-dione sodium salt, pharmaceutical preparations containing the same, method for production of said forms and use of said forms for modulating the immune system |
EP2688565A1 (en) | 2011-03-23 | 2014-01-29 | Semorex Technologies Ltd. | Treatment of proliferative disorders with a chemiluminescent agent |
JP2017537958A (ja) * | 2014-12-18 | 2017-12-21 | メトリオファーム アーゲー | 5−アミノ−2,3−ジヒドロフタラジン1,4−ジオンナトリウム塩の結晶形態、同一物を含む医薬製剤、及びこの形態の製造ための方法 |
CA3011767C (en) | 2016-02-16 | 2024-02-06 | Metriopharm Ag | Crystalline form of 5-amino-2,3-dihydrophthalazine-1,4-dione |
ES2796476T3 (es) * | 2016-02-16 | 2020-11-27 | Metriopharm Ag | Procedimiento para la producción de una forma cristalina de 5-amino-2,3-dihidroftalazina-1,4-diona |
EP3248602A1 (en) * | 2016-05-26 | 2017-11-29 | MetrioPharm AG | Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of inflammatory and/or degenerative disorders of the tendons, ligaments of the joints, articular capsules and bursae |
WO2018082814A1 (en) | 2016-11-07 | 2018-05-11 | Metriopharm Ag | Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of chronic progressive multiple sclerosis |
EP4125802A1 (en) * | 2020-03-25 | 2023-02-08 | MetrioPharm AG | 5-amino-2,3-dihydro-1,4-phthalazinedione for treatment of acute lung injury |
RU2747467C1 (ru) * | 2020-07-17 | 2021-05-05 | Муса Тажудинович Абидов | Способ защиты от коронавирусной инфекции |
-
2021
- 2021-06-09 EP EP21732191.8A patent/EP4164651A1/en active Pending
- 2021-06-09 IL IL298899A patent/IL298899A/en unknown
- 2021-06-09 US US18/001,034 patent/US20230218614A1/en active Pending
- 2021-06-09 MX MX2022015601A patent/MX2022015601A/es unknown
- 2021-06-09 CN CN202180056484.XA patent/CN116075306A/zh active Pending
- 2021-06-09 KR KR1020237000847A patent/KR20230027150A/ko unknown
- 2021-06-09 JP JP2023506134A patent/JP2023529022A/ja active Pending
- 2021-06-09 BR BR112022025134A patent/BR112022025134A2/pt unknown
- 2021-06-09 AU AU2021288757A patent/AU2021288757A1/en active Pending
- 2021-06-09 CA CA3182022A patent/CA3182022A1/en active Pending
- 2021-06-09 WO PCT/EP2021/000071 patent/WO2021249667A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN116075306A (zh) | 2023-05-05 |
EP4164651A1 (en) | 2023-04-19 |
WO2021249667A1 (en) | 2021-12-16 |
US20230218614A1 (en) | 2023-07-13 |
AU2021288757A1 (en) | 2023-02-02 |
IL298899A (en) | 2023-02-01 |
JP2023529022A (ja) | 2023-07-06 |
BR112022025134A2 (pt) | 2022-12-27 |
CA3182022A1 (en) | 2021-12-16 |
KR20230027150A (ko) | 2023-02-27 |
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