WO2018117462A3 - 신규한 비브리오 파라헤몰리티쿠스 박테리오파지 Vib-PAP-4 및 이의 비브리오 파라헤몰리티쿠스 균 증식 억제 용도 - Google Patents

신규한 비브리오 파라헤몰리티쿠스 박테리오파지 Vib-PAP-4 및 이의 비브리오 파라헤몰리티쿠스 균 증식 억제 용도 Download PDF

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WO2018117462A3
WO2018117462A3 PCT/KR2017/013765 KR2017013765W WO2018117462A3 WO 2018117462 A3 WO2018117462 A3 WO 2018117462A3 KR 2017013765 W KR2017013765 W KR 2017013765W WO 2018117462 A3 WO2018117462 A3 WO 2018117462A3
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vibrio
bacteria
pap
vibrio parahaemolyticus
parahaemoliticus
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PCT/KR2017/013765
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English (en)
French (fr)
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WO2018117462A2 (ko
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윤성준
전수연
권안성
송현민
황순혜
강상현
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주식회사 인트론바이오테크놀로지
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Priority to US16/471,051 priority Critical patent/US11679137B2/en
Priority to CN201780079660.5A priority patent/CN110214181A/zh
Publication of WO2018117462A2 publication Critical patent/WO2018117462A2/ko
Publication of WO2018117462A3 publication Critical patent/WO2018117462A3/ko

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    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
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Abstract

본 발명은 비브리오 파라헤몰리티쿠스 균을 특이적으로 사멸시킬 수 있는 능력을 갖고 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리한 미오비리대 박테리오파지 Vib-PAP-4(수탁번호 KCTC 13168BP), 및 이를 유효성분으로 포함하는 조성물을 이용한 비브리오 파라헤몰리티쿠스 균의 감염을 방지 및 비브리오 파라헤몰리티쿠스 균의 감염을 치료하는 방법에 관한 것이다.
PCT/KR2017/013765 2016-12-21 2017-11-29 신규한 비브리오 파라헤몰리티쿠스 박테리오파지 Vib-PAP-4 및 이의 비브리오 파라헤몰리티쿠스 균 증식 억제 용도 WO2018117462A2 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US16/471,051 US11679137B2 (en) 2016-12-21 2017-11-29 Vibrio parahaemolyticus bacteriophage Vib-PAP-4 and use thereof in inhibiting proliferation of Vibrio parahaemoliticus bacteria
CN201780079660.5A CN110214181A (zh) 2016-12-21 2017-11-29 新型副溶血弧菌噬菌体vib-pap-4及其用于抑制副溶血弧菌细菌增殖的用途

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2016-0175223 2016-12-21
KR1020160175223A KR20180072055A (ko) 2016-12-21 2016-12-21 신규한 비브리오 파라헤몰리티쿠스 박테리오파지 Vib-PAP-4 및 이의 비브리오 파라헤몰리티쿠스 균 증식 억제 용도

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WO2018117462A2 WO2018117462A2 (ko) 2018-06-28
WO2018117462A3 true WO2018117462A3 (ko) 2019-01-24

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US (1) US11679137B2 (ko)
KR (1) KR20180072055A (ko)
CN (1) CN110214181A (ko)
WO (1) WO2018117462A2 (ko)

Families Citing this family (2)

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Publication number Priority date Publication date Assignee Title
KR101915486B1 (ko) * 2017-05-10 2018-11-08 주식회사 인트론바이오테크놀로지 신규한 비브리오 파라헤몰리티쿠스 박테리오파지 Vib-PAP-7 및 이의 비브리오 파라헤몰리티쿠스 균 증식 억제 용도
CN114672467A (zh) * 2022-04-11 2022-06-28 扬州大学 一种防治凡纳滨对虾副溶血弧菌的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130021677A (ko) * 2011-08-23 2013-03-06 경희대학교 산학협력단 식중독을 유발하는 살모넬라에 특이적 사멸능을 갖는 박테리오파지
KR20140000541A (ko) * 2012-06-25 2014-01-03 주식회사 씨티씨바이오 신규한 박테리오파지 pvp-1 및 이의 비브리오 파라헤몰리티쿠스 증식 억제 용도
KR20150024115A (ko) * 2013-08-26 2015-03-06 군산대학교산학협력단 바실러스 서브틸러스 및 파지 혼합물을 유효성분으로 함유하는 어류용 프로바이오틱스 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101798568B (zh) * 2009-04-03 2012-06-20 珠海市晋平科技有限公司 一种分离的副溶血弧菌噬菌体及其在杀菌和防菌中的应用
US9504721B2 (en) 2012-06-04 2016-11-29 Ctc Bio, Inc. Bacteriophage and its use for preventing proliferation of pathogenic bacteria
WO2013191363A1 (ko) * 2012-06-22 2013-12-27 주식회사 씨티씨바이오 신규한 박테리오파지 및 병원성 박테리아 증식 억제 용도
KR101592175B1 (ko) * 2014-04-29 2016-02-05 주식회사 인트론바이오테크놀로지 스트렙토코커스 파라우베리스 감염을 방지 및 처치하는 방법
KR101727456B1 (ko) * 2015-12-21 2017-04-17 주식회사 인트론바이오테크놀로지 신규한 비브리오 파라헤몰리티쿠스 박테리오파지 Vib-PAP-1 및 이의 비브리오 파라헤몰리티쿠스 균 증식 억제 용도
KR101915486B1 (ko) * 2017-05-10 2018-11-08 주식회사 인트론바이오테크놀로지 신규한 비브리오 파라헤몰리티쿠스 박테리오파지 Vib-PAP-7 및 이의 비브리오 파라헤몰리티쿠스 균 증식 억제 용도
CN112760296B (zh) * 2021-01-29 2022-06-17 青岛润达生物科技有限公司 一株副溶血弧菌噬菌体rdp-vp-19010及其应用
CN113368221A (zh) * 2021-06-21 2021-09-10 南京北极光生物科技有限公司 一种组合物、制备方法及其在治疗细菌性疾病中的应用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130021677A (ko) * 2011-08-23 2013-03-06 경희대학교 산학협력단 식중독을 유발하는 살모넬라에 특이적 사멸능을 갖는 박테리오파지
KR20140000541A (ko) * 2012-06-25 2014-01-03 주식회사 씨티씨바이오 신규한 박테리오파지 pvp-1 및 이의 비브리오 파라헤몰리티쿠스 증식 억제 용도
KR20150024115A (ko) * 2013-08-26 2015-03-06 군산대학교산학협력단 바실러스 서브틸러스 및 파지 혼합물을 유효성분으로 함유하는 어류용 프로바이오틱스 조성물

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ALANIS VILLA, A. ET AL.: "Genome Sequence of Temperate Vibrio Parahaemolyticus Bacteriophage vB VpaS MARIO", JOURNAL OF VIROLOGY, vol. 86, no. 24, December 2012 (2012-12-01), pages 13851 - 13852 *
JUN, J. W. ET AL.: "Bacteriophage Therapy of a Vibrio Parahaemolyticus Infection Caused by a Multiple-antibiotic-resistant 03:K6 Pandemic Clinical Strain", J. INFECT. DIS., vol. 210, no. 1, 1 July 2014 (2014-07-01), pages 72 - 78, XP055245527 *

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KR20180072055A (ko) 2018-06-29
US11679137B2 (en) 2023-06-20
CN110214181A (zh) 2019-09-06
WO2018117462A2 (ko) 2018-06-28
US20190328803A1 (en) 2019-10-31

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