WO2018068685A1

WO2018068685A1 - Sealing device

Info

Publication number: WO2018068685A1
Application number: PCT/CN2017/105281
Authority: WO
Inventors: 胡绍勤; 汤丽芬
Original assignee: 胡绍勤
Priority date: 2016-01-02
Filing date: 2017-10-08
Publication date: 2018-04-19
Also published as: CN105501642A; WO2018068684A1; CN107007901A; WO2017113934A1; CN207693916U; CN207693917U; CN207693915U; WO2018068686A1

Abstract

A sealing device comprises a main body (1) provided with a partitionable space. The partitionable space is partitioned into a first partition space (16) and a second partition space (17) by the main body (1). The main body (1) is provided with a first body portion (10) and a second body portion (11). An outer side of the first body portion (10) is covered with a light shielding material (4), and/or the light shielding material (4) is sandwiched by the first body portion (10). An outer side of the second body portion (11) is covered with the light shielding material (4), and/or the light shielding material (4) is sandwiched by the second body portion (11). In the gap between the light shielding material (4) on the first body portion (10) and the light shielding material (4) on the second body portion (11), there is provided a shielding member (43) which at least shields one side of the gap and exceeds the length of the gap. By providing a separation material (42), the issue of easily photo-decomposable material to be shielded reacting with other materials contacted with and thus undergoing changes in physical and chemical properties is solved. By providing the shielding member (43) the stability of easily photo-decomposable materials can be ensured and excellent light shielding performance can be maintained. The sealing device of the present invention has application in the field of medical packaging materials.

Description

Sealing device

Technical field

The present invention relates to the field of medical packaging materials, and in particular to a sealing device.

Background technique

In daily life, it is often necessary to apply a light-shielding material to separate storage, infusion therapy, and transport of some special materials (such as photo-decomposable drugs, reagents, preparations, and materials). Clinically, some drugs have poor stability. When dissolved, they are prone to oxidation, decomposition, discoloration, etc.; some chemotherapeutic drugs can undergo complex reactions such as splitting, rearrangement, hydrolysis, polymerization, oxidation, and isomerization. Light can catalyze the progress of the above reaction. However, when the light-shielding material is in direct contact with the light-decomposable substance, it often affects the physical and chemical properties of the drug or material or other chemical reactions.

Current light-proof products have gaps between the light-shielding materials, which cause light to enter the dark-proof article from between the gaps, thereby reducing the light-proof performance.

There is a need in the clinic for a seal that is light-proof and safe to use.

Summary of the invention

In order to solve the above problems, the present invention provides a sealing device which is good in light protection and can be used safely.

The technical solution adopted by the present invention to solve the technical problem thereof is:

A sealing device comprising a body provided with a separable space; the separable space is partitioned into a first partition space and a second partition space by a body; the body is provided with a first body and a second body; The outer side of a body covers the light-proof material and/or the first body The light shielding material is sandwiched on the outer side; the outer side of the second body is covered with the light shielding material and/or the light shielding material is sandwiched on the second body; the light shielding material on the first body is separated from the light shielding material on the second body The gap is provided with a shutter that blocks at least one side of the gap and exceeds the length of the gap.

Further, as an improvement of the technical solution of the present invention, the light-shielding material and the light-decomposable substance that is expected to be shielded are separated by at least one layer of separation material, and the separation material is not in contact with the light-decomposable substance that is expected to be shielded; Or the light-shielding material and the light-decomposable substance that is expected to be shielded are separated by at least one layer of separation material, and the light-decomposable substance that is expected to be shielded is not in contact with the separation material, and the physical and chemical properties are not changed; or the light-proof material is expected to be The masked light-decomposable materials are separated by at least one layer of a separating material that is in contact with the light-decomposable material that is intended to be shielded from each other without physical and chemical properties being altered.

Further, as an improvement of the technical solution of the present invention, at least a layer of colorless and transparent polymer material is interposed between the light-proof material and the light-decomposable substance that is expected to be shielded.

Further as an improvement of the technical solution of the present invention, the first body and/or the second body are disposed around the outer periphery of the light-decomposable substance that is intended to be shielded; or the first body and/or the second body are easily decomposed around the light that is intended to be shielded. a substance setting; or the first body and/or the second body is disposed between two light-decomposable substances that are intended to be shielded; or the first body and/or the second body is disposed on a non-photodecomposable substance and is expected The shielded light is easily decomposed between the substances; or the first body and/or the second body is disposed on a container opening of the peripheral device for storing the light-decomposable substance that is intended to be shielded; or the first body and/or the second body The first body and/or the second body is provided with a connection port communicating with the liquid flow channel. The liquid flow path is disposed on the liquid flow path containing the liquid easily decomposable substance.

Further as an improvement of the technical solution of the present invention, the shutter is formed by folding and/or extending from a light-shielding material.

Further, as an improvement of the technical solution of the present invention, the light-proof material is made of a light-proof film.

Further, as an improvement of the technical solution of the present invention, the first body is provided with a fixing device for fixing the second body, and the first body is fixed by the fixing device; the fixing device adopts a heat welding or a solder joint structure or Adhesive or snap-on or threaded or spliced construction.

Further, as an improvement of the technical solution of the present invention, the first body is provided with a fixing device for fixing the second body, and the first body fixes the second body by the fixing device.

Further as an improvement of the technical solution of the present invention, the fixing device adopts a heat welded or a virtual welded structure or an adhesive or snap structure or a threaded structure or a spliced structure.

An infusion device comprising any of the above described sealing devices.

Further, as an improvement of the technical solution of the present invention, the infusion device is selected from the group consisting of an infusion line, an infusion set, an indwelling needle, an infusion needle, an infusion extension tube, a syringe, an infusion connector, an infusion connection tube, a drip bucket, and a filter.

A storage device comprising any of the above sealing devices.

Further, as an improvement of the technical solution of the present invention, the storage device is selected from the group consisting of an infusion bottle, an infusion bag, an ampoule, a medicine bottle, a reagent bottle, a medicine box, and a storage box.

The invention has the beneficial effects that the sealing device solves the expected light-decomposable substance by shielding at least between a light-proof material and a light-decomposable substance that is intended to be shielded with at least one layer of colorless transparent polymer material or other type of separating material. The material in contact with it appears to be reversed It should, as a result, cause problems in the physical and chemical properties of light-decomposable substances, and ensure the stability of light-decomposable substances.

By providing a shutter on the gap between the light-shielding materials, it is solved that the light enters from the gap, and the light-decomposable substance is decomposed by light, and the light-shielding performance is good.

DRAWINGS

The present invention will be further described below in conjunction with the accompanying drawings:

1 is a schematic view showing the overall structure of a first embodiment of the present invention;

Figure 2 is a schematic view showing the overall structure of a second embodiment of the present invention;

Figure 3 is a schematic view showing the overall structure of a third embodiment of the present invention;

Figure 4 is a schematic view showing the overall structure of a fourth embodiment of the present invention.

detailed description

Referring to FIGS. 1 to 2, a sealing device includes a body 1 provided with a separable space 15; the separable space 15 is partitioned by the body 1 into a first partition space 16 and a second partition space 17; The first body 10 and the second body 11 are disposed thereon; the outer side of the first body 10 covers the light-protecting material 4 and/or the first body 10 has a light-shielding material 4; the outer side of the second body 11 is covered The light-shielding material 4 and/or the second body 11 are sandwiched with the light-shielding material 4; the gap between the light-shielding material 4 on the first body 10 and the light-shielding material 4 on the second body 11 is at least blocked. A shutter 43 on one side of the gap and exceeding the gap gap length.

The first separation space 16 and the second separation space 17 may be two independent closed points. a space; or one of them may be a separate sealed space, and the other is an open space; or one of them may be a closed space that communicates with other spaces, and the other is an open space; or One is a closed compartment that is connected to other spaces, and the other is a separate, confined compartment.

As a preferred embodiment of the present invention, at least a layer of partitioning material 42 is interposed between the light-shielding material 4 and the light-decomposable substance that is intended to be shielded, and the partitioning material 42 is in contact with the light-decomposable substance that is intended to be shielded from physical and chemical properties. Changed; or at least a layer of separating material 42 is interposed between the light-shielding material 4 and the light-decomposable substance that is intended to be shielded, and the photo-decomposable substance that is expected to be shielded is not in contact with the partitioning material 42; At least a layer of separating material 42 is interposed between the light-shielding material 4 and the light-decomposable substance that is intended to be shielded, and the partitioning material 42 is in contact with the light-decomposable substance that is expected to be shielded without undergoing physical and chemical properties change from each other.

As a preferred embodiment of the present invention, at least a layer of colorless and transparent polymer material 420 is interposed between the light-protecting material 4 and the light-decomposable substance that is intended to be shielded.

Preferably, the first body and/or the second body are disposed as part or all of the partitioning material. Of course, the first body and the partitioning material, the second body and the partitioning material may also be disposed independently of each other.

Preferably, the partition material is a colorless and transparent polymer material.

By separating at least one layer of separation material between the light-shielding material and the light-decomposable substance that is expected to be shielded, at least a layer of colorless and transparent polymer material may be interposed between the light-proof material and the light-decomposable substance that is expected to be shielded. Resolve that the light-decomposable substance that is expected to be shielded reacts with the separating material that it contacts, resulting in a change in physical and chemical properties of the photodegradable material The problem of solving the problem is that the light-decomposable substance that is expected to be shielded reacts with the separating material that is in contact with it, resulting in a change in the physical and chemical properties of the partitioning material, thereby reducing the physical and chemical properties of the light-shielding material between the partitioning material and the light-shielding material which change the physical and chemical properties. The change affects the light-shielding property, which in turn leads to the problem of the change of physical and chemical properties of the photodegradable material.

Photodegradable materials that are expected to be masked include drugs, reagents, formulations, materials, and other materials that have photodegradable properties.

As a preferred embodiment of the present invention, the first body 10 and/or the second body 11 are disposed around the outer periphery of the light-decomposable substance that is intended to be shielded; or the first body 10 and/or the second body 11 are surrounded by the intended shielding. The light-decomposable substance is disposed; or the first body 10 and/or the second body 11 are disposed between two light-decomposable substances that are intended to be shielded; or the first body 10 and/or the second body 11 are disposed on Between the non-photodecomposable substance and the photo-decomposable substance that is intended to be shielded; or the first body 10 and/or the second body 11 is disposed on a container opening of the peripheral device for storing the light-decomposable substance that is intended to be shielded; or The first body 10 and/or the second body 11 are disposed on a liquid flow path of a liquid containing a photodecomposable substance, and the first body 10 and/or the second body 11 are provided with a connection port communicating with the liquid flow path.

As a preferred embodiment of the invention, the shutter 43 is formed by folding and/or extending from the light-proof material 4.

In a preferred embodiment of the present invention, the light-shielding material 4 is made of a light-shielding film 41. The light-shielding material can also be made of other materials such as aluminum foil, light-shielding paper, and opaque material. The light shielding material on the first body 10 and the second body 11 may be the same light shielding material, or two or more light shielding materials may be used.

As a preferred embodiment of the present invention, the first body 10 is provided with a fixing device for fixing the second body 11. The first body 10 fixes the second body 11 by a fixing device; the fixing device adopts heat welding or virtual Welded structure or adhesive or snap-on or threaded or spliced structure.

As a preferred embodiment of the present invention, the first body 10 is provided with fixing means for fixing the second body 11, and the first body 10 fixes the second body 11 by the fixing means.

As a preferred embodiment of the present invention, the fixing device employs a heat welded or soldered structure or an adhesive or snap structure or a threaded structure or a spliced structure. The fixing device can keep the first body and the second body from being loosened, resulting in an increase in the gap or even direct light entering the area to be protected from light.

Referring to Figure 3, an infusion set includes any of the above described sealing means.

In a preferred embodiment of the present invention, the infusion device is selected from the group consisting of an infusion line, an infusion set, an indwelling needle, an infusion needle, an infusion extension tube, a syringe, an infusion connector, an infusion connection tube, a drip chamber, and a filter.

Referring to Figure 4, a storage device includes any of the above described sealing devices.

As a preferred embodiment of the present invention, the storage device is selected from the group consisting of an infusion bottle, an infusion bag, an ampoule, a vial, a reagent bottle, a drug box, and a storage box.

Claims

A sealing device comprising a body provided with a separable space; the separable space is partitioned into a first partition space and a second partition space by a body; the body is provided with a first body and a second body; The outer side of a body covers the light-proof material and/or the first body has a light-shielding material; the outer side of the second body covers the light-proof material and/or the second body has a light-shielding material; the first body A gap between the upper light-proof material and the light-shielding material on the second body is provided with a shutter that blocks at least one side of the gap and exceeds the gap length.
The sealing device according to claim 1, wherein at least a layer of partitioning material is interposed between said light-shielding material and a light-decomposable substance that is intended to be shielded, and said partitioning material is in contact with the light-decomposable substance that is intended to be shielded. Having a change in physical and chemical properties; or at least a layer of separating material between the light-shielding material and the photo-decomposable material that is expected to be shielded, and the photo-decomposable substance that is expected to be shielded from contacting the separating material does not undergo physical and chemical properties change; At least a layer of spacer material is interposed between the light-shielding material and the photo-decomposable material that is expected to be shielded, and the spacer material is in contact with the photo-decomposable substance that is intended to be shielded without undergoing physical and chemical properties change from each other.
The sealing device according to claim 1, wherein at least one layer of colorless and transparent polymer material is interposed between the light-shielding material and the light-shielding drug to be shielded.
The sealing device according to claim 1, wherein the first body and/or the second body are disposed around the outer periphery of the light-decomposable substance that is intended to be shielded; or the first body and/or the second body surround the expected Shaded light easily decomposable material set; or The first body and/or the second body are disposed between two light-decomposable substances that are intended to be shielded; or the first body and/or the second body are disposed on the non-photodecomposable substance and the light that is intended to be shielded Between the easily decomposable substances; or the first body and/or the second body is disposed on a container opening of the peripheral device for storing the light-decomposable substance that is intended to be shielded; or the first body and/or the second body is disposed to be contained On the liquid flow path of the liquid of the light-decomposable substance, the first body and/or the second body are provided with a connection port communicating with the liquid flow path.
A sealing device according to claim 1 wherein said shutter is formed by folding and/or extending from a light-protecting material.
The sealing device according to claim 1, wherein the first body is provided with fixing means for fixing the second body, the first body fixing the second body by the fixing device; the fixing device is thermally welded Or a solder joint structure or an adhesive or snap structure or a threaded structure or a hinged structure.
An infusion device comprising the sealing device of any of claims 1 to 6.
The infusion device according to claim 7, wherein the infusion device is selected from the group consisting of an infusion line, an infusion set, an indwelling needle, an infusion needle, an infusion extension tube, a syringe, an infusion connector, an infusion connection tube, and a drop. Bucket, filter.
A storage device comprising the sealing device according to any one of claims 1 to 6.
The storage device according to claim 9, wherein the storage device is selected from the group consisting of an infusion bottle, an infusion bag, an ampoule, a vial, a reagent bottle, a drug box, and a storage case.