US3343541A - Parenteral container - Google Patents

Parenteral container Download PDF

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Publication number
US3343541A
US3343541A US336569A US33656964A US3343541A US 3343541 A US3343541 A US 3343541A US 336569 A US336569 A US 336569A US 33656964 A US33656964 A US 33656964A US 3343541 A US3343541 A US 3343541A
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US
United States
Prior art keywords
port
film
container
tamper proof
closure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US336569A
Inventor
Jr David Bellamy
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Baxter Laboratories Inc
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Baxter Laboratories Inc
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Publication date
Application filed by Baxter Laboratories Inc filed Critical Baxter Laboratories Inc
Priority to US336569A priority Critical patent/US3343541A/en
Application granted granted Critical
Publication of US3343541A publication Critical patent/US3343541A/en
Anticipated expiration legal-status Critical
Application status is Expired - Lifetime legal-status Critical

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor

Description

Sept. 26, 1967 D. BELLAMY, JR 3,343,541

PARENTERAL CONTAINER Filed Jan. 8, 1964 INVENTOR. DAVID BELLAMY JR.

MP by ATTORNEY United States Patent 3,343,541 PARENTERAL CONTAINER David Bellamy, Jr., Glenview, 11]., assignor to Baxter Laboratories, 1120., Morton Grove, 111., a corporation of Delaware Filed Jan. 8, 1964, Ser. No. 336,569 1 Claim. (Cl. 128-272) The present invention relates to a parenteral solution container provided with a tamper proof closure. More particularly, it relates to a plastic parenteral solution container with a closure structure which provides for a sterile port means and a sterile zone about the port means.

Various attempts have been made to prepare a plastic parenteral solution bag with a tamper proof closure. For the most part these attempts have comprised placing a rubber stopper in the opening of the outlet port and attaching a tamper proof metal collar to the port or embedding the entire port structure and stopper in plastic. Such closure systems, although they are tamper proof, possess several disadvantages. First, they are diflicult and uneconomic-a1 to assemble; second, they are difficult to disassemble without violating the sterility of the port; and third, even though the port itself is sterile often the area immediately surrounding the port becomes highly contaminated and presents a hazard which can lead to contamination of the port structure and the contents of the solution container.

It is an object of the present invention to provide a closure structure for a plastic solution bag which is tamper proof, easy to assemble and disassemble, and furthermore, provides a sterile zone about the port.

This and still other objects and advantages will be apparent from the description which follows.

It has now been discovered that a plastic solution container with a superior tamper proof closure may be prepared by sealing a section of relatively thin tearable plastic film to the container about and surrounding the port area. The tearable film is preferably provided with tab means for rupturing said film to expose the port area. The tab means may be a relatively thicker plastic film which is sealed to the tearable film within the periphery of the seal which attaches the tearable film to the bag.

In further describing the invention reference will be had to the drawings in which:

FIGURE 1 is an elevational view showing one embodiment of the novel tamper proof closure of the present invention.

FIGURE 2 is a sectional view taken along lines 2-2 of FIGURE 1 showing the details of the port and closure structure.

FIGURE 3 is an elevational view of the embodiment of FIGURE 1 showing the method of exposing the sterile port area.

In FIGURE 1 is seen a plastic solution container 10 provided with hanger means 11, port 12, and a tamper proof protective closure for said port generally referred to as 13. As seen in FIGURES 1 and 2, the protective closure 13 comprises a section of relatively thin film 14 which is attached to the solution container 10 by a seal 15 about its periphery. Within the periphery of the seal lies the port structure 12. Attached to the tearable film 14 is a section of relatively thick film 16 which is united to the tearable film by a seal 17 which lies within the area bounded by the seal 15. As seen in FIGURE 2, the seal 17 is spaced in from the boundaries of the seal 15 thus creating the tab means 18. The tab means 18 are adapted to be grasped as shown in FIGURE 3 and manipulated to expose the port and the adjacent sterile area. To fur ther facilitate the removal or the tearing of the tearable film 14 the seal 17 may be shaped as shown in FIGURES 3,343,541 Patented Sept. 26, 1967 l and 3. If desired, additional ports may be included within the sterile zone. For example, a second port which is provided with a resealable stopper might be included to provide for the administration of supplemental medication.

In the preferred embodiment of the present invention, the bag 10 is formed of polyvinylchloride resin or a laminate thereof; the section of tearable film 14 is formed of a relatively thin polyvinylchloride resin film about 0.006 inch thick, and the section of relatively thick film 16 is formed of polyvinylchloride resin film about 0.015 inch thick. If desired the tab means 18 may be ribbed or otherwise modified to provide a secure gripping surface (as seen in FIGURE 3). The use of the polyvinylchloride resin for all three components is preferred because of the ease with which components formed of that resin may be sealed to each other.

If desired, the novel tamper proof closure may be sealed to the container immediately after the container has been filled with solution. However, in a completely automated operation in which the solution bag is simultaneously formed, filled and sterilized, it may be desirable to have the tamper proof closure already attached to one of the sheets of plastic which will eventually form a wall of the container. If such is the case the tamper proof closure and the zone it protects might be sterilized separately as by gas sterilization or sterilized with the bag and its contents by any conventional sterilization technique.

In the embodiment illustrated in the drawings a sterile zone is provided only in the area immediately adjacent the port structure, however, it may in some circumstances be desirable to more or less completely enclose the side of the solution bag within the tamper proof protective closure. For example, if desired, a parenteral solution administration set may be integrally connected to the bag and completely enclosed within the novel tamper proof closure system of the present invention. This method of construction would provide substantial advantages for military use where a single sterile compact unit for parenteral administration is desired. In such a case the sterile zone provided would have to be much larger than that required when a separate unconnected administration set is to "be employed. The integral parenteral solution administration set referred to is a modified outlet port and is intended to be covered by the term port as used herein.

It may also be desirable for the tearable film 14 to be provided with printed directions as to method of use, description of the contents, etc., thereby eliminating the necessity of printing such data directly upon the wall of the parenteral solution container. This has the advantage of effectively protecting against the migration of any of the ingredients of the printing materials through the wall of the container and into the parenteral solution.

While in the preferred practice, the films to be employed have been described as being of polyvinylchloride resin it will be understood that other plastics which are equivalent to the polyvinylchloride resin for this particular use such as polyolefin resins, polyhalocarbon resins and the like may be used and are intended to be covered by the term polyvinylchloride resin as used herein.

It will be further understood that the tamper proof clo sure of the present invention may be sealed to the parenteral solution bag by heat sealing, dielectric sealing, ultrasonic sealing, gluing or any other suitable means.

It will be readily apparent to those skilled in the art that the present invention provides many substantial advantages over the practice of the prior art. Some of these advantages have been described, still others will be apparent to those skilled in the art.

What I claim is:

In a plastic solution bag for containing a sterile par- M enteral solution and provided with port means including a tubular extension through the wall of said bag, a tamper proof closure for said port means comprising a relatively thin tearable plastic film permanently sealed to said hag around its edges and encompassing a sterile zone, said port means being located within said sterile zone, tab means for rupturing said tearable plastic film to expose the sterile zone and port means, said tab means including a relatively thick tear tab being located within the periphery of the seal which joins the thin plastic film to the bag.

References Cited UNITED STATES PATENTS Cherkin 128-272 Spees 229-51 Flynn 128-214 Spees.

Cocoran et a1 128-272 Barton et al. 128-272 X 10 RICHARD A. GAUDET, Primary Examiner.

DALTON L. TRULUCK, Examiner.

US336569A 1964-01-08 1964-01-08 Parenteral container Expired - Lifetime US3343541A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US336569A US3343541A (en) 1964-01-08 1964-01-08 Parenteral container

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US336569A US3343541A (en) 1964-01-08 1964-01-08 Parenteral container
GB4198764A GB1081900A (en) 1964-01-08 1964-10-14 Plastic bags with apertures for dispensing contents
DK530564A DK117243B (en) 1964-01-08 1964-10-28 Plastic container, particularly for dispensing a sterile liquid.
NL6412577A NL6412577A (en) 1964-01-08 1964-10-29
BE655158D BE655158A (en) 1964-01-08 1964-11-03
SE1332764A SE323764B (en) 1964-01-08 1964-11-05
CH1438164A CH431816A (en) 1964-01-08 1964-11-06 Plastic container for dispensing a sterile solution
DE19641492296 DE1492296C3 (en) 1964-01-08 1964-11-20
FR954A FR1419521A (en) 1964-01-08 1965-01-06 Container for injectable solutions for parenteral use and shutter device

Publications (1)

Publication Number Publication Date
US3343541A true US3343541A (en) 1967-09-26

Family

ID=23316685

Family Applications (1)

Application Number Title Priority Date Filing Date
US336569A Expired - Lifetime US3343541A (en) 1964-01-08 1964-01-08 Parenteral container

Country Status (9)

Country Link
US (1) US3343541A (en)
BE (1) BE655158A (en)
CH (1) CH431816A (en)
DE (1) DE1492296C3 (en)
DK (1) DK117243B (en)
FR (1) FR1419521A (en)
GB (1) GB1081900A (en)
NL (1) NL6412577A (en)
SE (1) SE323764B (en)

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565075A (en) * 1968-05-02 1971-02-23 Frederick Lonnie Jerry Bandage
US3788374A (en) * 1972-01-26 1974-01-29 Jintan Terumo Co Parenteral solution bag
US4234026A (en) * 1979-03-05 1980-11-18 Baxter Travenol Laboratories, Inc. Seal for flexible container
US4294574A (en) * 1979-03-05 1981-10-13 Baxter Travenol Laboratories, Inc. Method of making seal for flexible container
EP0097054A2 (en) * 1982-06-15 1983-12-28 Hantaaki Oy Injection port for plastic bags
US4507114A (en) * 1983-10-21 1985-03-26 Baxter Travenol Laboratories, Inc. Multiple chamber container having leak detection compartment
US4630729A (en) * 1984-07-27 1986-12-23 Firma Dixie Union Verpackungen Gmbh Package, for example, for surgical instruments and products
US4632673A (en) * 1983-06-15 1986-12-30 Hantaaki Oy Pierceable port for containers
US4787222A (en) * 1986-11-24 1988-11-29 Novatek Medical Inc. Combination lock for blood identification system
US4808179A (en) * 1984-05-09 1989-02-28 Ab Akerlund & Rausing Container device and a method for manufacturing of the device
US4823806A (en) * 1985-11-18 1989-04-25 Serge Bajada Apparatus for testing the sensory system on humans or animals
US4838429A (en) * 1986-10-10 1989-06-13 Baxter International Inc. Flexible thermoplastic pouches having easy-open tear strip means and apparatus for making same
US4917684A (en) * 1986-09-01 1990-04-17 Japan Medical Supply Co., Ltd. Protective cover for inlet/outlet ports of the plastic bag used for medical purpose
US5246011A (en) * 1992-01-30 1993-09-21 Caillouette James C Fine needle aspiration syringe
US5395365A (en) * 1993-03-22 1995-03-07 Automatic Liquid Packaging, Inc. Container with pierceable and/or collapsible features
US6267564B1 (en) 1999-05-12 2001-07-31 Sims Deltec, Inc. Medical reservoir bag and system
US6309105B1 (en) * 1994-10-07 2001-10-30 The Procter & Gamble Company Resealable pack
US7963413B2 (en) 2006-05-23 2011-06-21 Kraft Foods Global Brands Llc Tamper evident resealable closure
US8114451B2 (en) 2006-12-27 2012-02-14 Kraft Foods Global Brands Llc Resealable closure with package integrity feature
US8308363B2 (en) 2006-05-23 2012-11-13 Kraft Foods Global Brands Llc Package integrity indicator for container closure
US8408792B2 (en) 2007-03-30 2013-04-02 Kraft Foods Global Brands Llc Package integrity indicating closure
US9150342B2 (en) 2003-04-16 2015-10-06 Intercontinental Great Brands Llc Resealable tray container
US9205967B2 (en) 2010-01-26 2015-12-08 Generale Biscuit Resealable packaging for food products and method of manufacturing
US9221590B2 (en) 2010-03-23 2015-12-29 Generale Biscuit Resealable packaging for food products and method of manufacturing
US9630761B2 (en) 2008-10-20 2017-04-25 Mondelez UK Holding & Services Limited Packaging
US9656783B2 (en) 2010-05-18 2017-05-23 Intercontinental Great Brands Llc Reclosable flexible packaging and methods for manufacturing same
US9688442B2 (en) 2011-03-17 2017-06-27 Intercontinental Great Brands Llc Reclosable flexible film packaging products and methods of manufacture
US9708104B2 (en) 2010-05-18 2017-07-18 Intercontinental Great Brands Llc Reclosable flexible packaging and methods for manufacturing same
US10118741B2 (en) 2008-07-24 2018-11-06 Deborah Lyzenga Package integrity indicating closure

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2117349B (en) * 1982-03-24 1985-09-11 Metal Box Plc Bags
US4510115A (en) * 1982-11-03 1985-04-09 Baxter Travenol Laboratories, Inc. Method for forming layered thermoplastic articles
DE3634718A1 (en) * 1986-10-11 1988-04-14 Schiwa Gmbh Using a large-volume supply bag for dialysis concentrates

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2704075A (en) * 1952-03-10 1955-03-15 Baxter Don Inc Flexible plastic container
US2991000A (en) * 1956-10-04 1961-07-04 Arthur T Spees Tear strip means for plastic packaging
US2997043A (en) * 1954-08-17 1961-08-22 Becton Dickinson Co Protective cannula sheath
US3053385A (en) * 1958-12-16 1962-09-11 Arthur T Spees Disposable applicator
US3064652A (en) * 1960-02-11 1962-11-20 Baxter Don Inc Transfusion equipment
US3161310A (en) * 1960-10-14 1964-12-15 Baxter Don Inc Parenteral solution container

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2704075A (en) * 1952-03-10 1955-03-15 Baxter Don Inc Flexible plastic container
US2997043A (en) * 1954-08-17 1961-08-22 Becton Dickinson Co Protective cannula sheath
US2991000A (en) * 1956-10-04 1961-07-04 Arthur T Spees Tear strip means for plastic packaging
US3053385A (en) * 1958-12-16 1962-09-11 Arthur T Spees Disposable applicator
US3064652A (en) * 1960-02-11 1962-11-20 Baxter Don Inc Transfusion equipment
US3161310A (en) * 1960-10-14 1964-12-15 Baxter Don Inc Parenteral solution container

Cited By (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565075A (en) * 1968-05-02 1971-02-23 Frederick Lonnie Jerry Bandage
US3788374A (en) * 1972-01-26 1974-01-29 Jintan Terumo Co Parenteral solution bag
US4234026A (en) * 1979-03-05 1980-11-18 Baxter Travenol Laboratories, Inc. Seal for flexible container
US4294574A (en) * 1979-03-05 1981-10-13 Baxter Travenol Laboratories, Inc. Method of making seal for flexible container
EP0097054A3 (en) * 1982-06-15 1984-12-12 Hantaaki Oy Injection port for plastic bags
EP0097054A2 (en) * 1982-06-15 1983-12-28 Hantaaki Oy Injection port for plastic bags
WO1984000025A1 (en) * 1982-06-15 1984-01-05 Hantaaki Oy Injection port for plastic bags
US4632673A (en) * 1983-06-15 1986-12-30 Hantaaki Oy Pierceable port for containers
US4507114A (en) * 1983-10-21 1985-03-26 Baxter Travenol Laboratories, Inc. Multiple chamber container having leak detection compartment
WO1985001716A1 (en) * 1983-10-21 1985-04-25 Baxter Travenol Laboratories, Inc. Multiple chamber container having leak detection compartment
US4808179A (en) * 1984-05-09 1989-02-28 Ab Akerlund & Rausing Container device and a method for manufacturing of the device
US4630729A (en) * 1984-07-27 1986-12-23 Firma Dixie Union Verpackungen Gmbh Package, for example, for surgical instruments and products
US4823806A (en) * 1985-11-18 1989-04-25 Serge Bajada Apparatus for testing the sensory system on humans or animals
US4917684A (en) * 1986-09-01 1990-04-17 Japan Medical Supply Co., Ltd. Protective cover for inlet/outlet ports of the plastic bag used for medical purpose
US4838429A (en) * 1986-10-10 1989-06-13 Baxter International Inc. Flexible thermoplastic pouches having easy-open tear strip means and apparatus for making same
US4787222A (en) * 1986-11-24 1988-11-29 Novatek Medical Inc. Combination lock for blood identification system
WO1990004076A1 (en) * 1988-10-05 1990-04-19 Novatek Medical, Inc. Combination lock for blood identification system
US5246011A (en) * 1992-01-30 1993-09-21 Caillouette James C Fine needle aspiration syringe
US5395365A (en) * 1993-03-22 1995-03-07 Automatic Liquid Packaging, Inc. Container with pierceable and/or collapsible features
US6309105B1 (en) * 1994-10-07 2001-10-30 The Procter & Gamble Company Resealable pack
US6267564B1 (en) 1999-05-12 2001-07-31 Sims Deltec, Inc. Medical reservoir bag and system
US9150342B2 (en) 2003-04-16 2015-10-06 Intercontinental Great Brands Llc Resealable tray container
US9663282B2 (en) 2006-05-23 2017-05-30 International Great Rapids LLC Package integrity indicator for container closure
US7963413B2 (en) 2006-05-23 2011-06-21 Kraft Foods Global Brands Llc Tamper evident resealable closure
US8951591B2 (en) 2006-05-23 2015-02-10 Intercontinental Great Brands Llc Package integrity indicator for container closure
US8722122B2 (en) 2006-05-23 2014-05-13 Intercontinental Great Brands Llc Package integrity indicator for container closure
US8746483B2 (en) 2006-05-23 2014-06-10 Intercontinental Great Brands Llc Tamper evident resealable closure
US8308363B2 (en) 2006-05-23 2012-11-13 Kraft Foods Global Brands Llc Package integrity indicator for container closure
US8889205B2 (en) 2006-12-27 2014-11-18 Intercontinental Great Brands Llc Resealable closure with package integrity feature
US8114451B2 (en) 2006-12-27 2012-02-14 Kraft Foods Global Brands Llc Resealable closure with package integrity feature
US8408792B2 (en) 2007-03-30 2013-04-02 Kraft Foods Global Brands Llc Package integrity indicating closure
US9919855B2 (en) 2007-03-30 2018-03-20 Intercontinental Great Brands Llc Package integrity indicating closure
US9187228B2 (en) 2007-03-30 2015-11-17 Intercontinental Great Brands Llc Package integrity indicating closure
US10118741B2 (en) 2008-07-24 2018-11-06 Deborah Lyzenga Package integrity indicating closure
US9630761B2 (en) 2008-10-20 2017-04-25 Mondelez UK Holding & Services Limited Packaging
US9205967B2 (en) 2010-01-26 2015-12-08 Generale Biscuit Resealable packaging for food products and method of manufacturing
US9221590B2 (en) 2010-03-23 2015-12-29 Generale Biscuit Resealable packaging for food products and method of manufacturing
US9656783B2 (en) 2010-05-18 2017-05-23 Intercontinental Great Brands Llc Reclosable flexible packaging and methods for manufacturing same
US9708104B2 (en) 2010-05-18 2017-07-18 Intercontinental Great Brands Llc Reclosable flexible packaging and methods for manufacturing same
US9688442B2 (en) 2011-03-17 2017-06-27 Intercontinental Great Brands Llc Reclosable flexible film packaging products and methods of manufacture

Also Published As

Publication number Publication date
NL6412577A (en) 1965-07-09
FR1419521A (en) 1965-11-26
CH431816A (en) 1967-03-15
DK117243B (en) 1970-03-31
BE655158A (en) 1965-03-01
GB1081900A (en) 1967-09-06
DE1492296A1 (en) 1970-01-15
SE323764B (en) 1970-05-11
DE1492296B2 (en) 1973-10-25
DE1492296C3 (en) 1974-05-30

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