WO2018004281A3 - 피부 미백 활성을 가지는 트라넥삼산-펩타이드 및 그 용도 - Google Patents

피부 미백 활성을 가지는 트라넥삼산-펩타이드 및 그 용도 Download PDF

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Publication number
WO2018004281A3
WO2018004281A3 PCT/KR2017/006919 KR2017006919W WO2018004281A3 WO 2018004281 A3 WO2018004281 A3 WO 2018004281A3 KR 2017006919 W KR2017006919 W KR 2017006919W WO 2018004281 A3 WO2018004281 A3 WO 2018004281A3
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WO
WIPO (PCT)
Prior art keywords
tranexamil
peptide
skin whitening
tranexamic acid
whitening activity
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Application number
PCT/KR2017/006919
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English (en)
French (fr)
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WO2018004281A2 (ko
Inventor
강상문
황석연
임미혜
박청
신은진
이기영
박운규
임현지
양동현
차상주
Original Assignee
에이엔펩주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60787380&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2018004281(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 에이엔펩주식회사 filed Critical 에이엔펩주식회사
Priority to US16/305,492 priority Critical patent/US10532018B2/en
Priority to CN201780034067.9A priority patent/CN109311938B/zh
Publication of WO2018004281A2 publication Critical patent/WO2018004281A2/ko
Publication of WO2018004281A3 publication Critical patent/WO2018004281A3/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
    • C07C223/04—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

피부의 턴오버 개선을 통한 미백 효과 및 건강한 피부로의 회귀를 유도하는 것이 가능하며, 피부 미백효과 및 열적안정성과 시간안정성이 뛰어난 피부 미백 활성을 가지는 트라넥삼산-펩타이드 및 그 용도가 개시된다, 본 발명은 트라넥사밀-AS, 트라넥사밀-AT, 트라넥사밀-AP, 트라넥사밀-GP, 트라넥사밀-ES, 트라넥사밀-KK, 트라넥사밀-HK, 트라넥사밀-MY, 트라넥사밀-GH, 트라넥사밀-MA, 트라넥사밀-AH, 트라넥사밀-CC, 트라넥사밀-SA, 트라넥사밀-WA, 트라넥사밀-WE, 트라넥사밀-KD, 트라넥사밀-NA, 트라넥사밀-TS, 트라넥사밀-SS, 트라넥사밀-EC, 트라넥사밀-TA, 트라넥사밀-PF, 트라넥사밀-VS, 트라넥사밀-VV, 트라넥사밀-VP, 트라넥사밀-AA, 트라넥사밀-PS, 트라넥사밀-HA, 트라넥사밀-GK, 트라넥사밀-KV, 트라넥사밀-AR, 트라넥사밀-RP, 트라넥사밀-PQ, 트라넥사밀-QG, 트라넥사밀-PP, 트라넥사밀-VR, 트라넥사밀-SV, 트라넥사밀-ET, 트라넥사밀-CG 및 트라넥사밀-NT로 구성된 군 에서 선택되는 피부 미백 활성을 나타내는 트라넥삼산-펩타이드를 제공한다.
PCT/KR2017/006919 2016-06-29 2017-06-29 피부 미백 활성을 가지는 트라넥삼산-펩타이드 및 그 용도 WO2018004281A2 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US16/305,492 US10532018B2 (en) 2016-06-29 2017-06-29 Method of whitening skin using tranexamic acid-peptide having skin whitening activity
CN201780034067.9A CN109311938B (zh) 2016-06-29 2017-06-29 具有皮肤美白活性的凝血酸-肽及其用途

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2016-0081998 2016-06-29
KR1020160081998A KR101848887B1 (ko) 2016-06-29 2016-06-29 피부 미백 활성을 가지는 트라넥삼산-펩타이드 및 그 용도

Publications (2)

Publication Number Publication Date
WO2018004281A2 WO2018004281A2 (ko) 2018-01-04
WO2018004281A3 true WO2018004281A3 (ko) 2018-02-22

Family

ID=60787380

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2017/006919 WO2018004281A2 (ko) 2016-06-29 2017-06-29 피부 미백 활성을 가지는 트라넥삼산-펩타이드 및 그 용도

Country Status (4)

Country Link
US (1) US10532018B2 (ko)
KR (1) KR101848887B1 (ko)
CN (1) CN109311938B (ko)
WO (1) WO2018004281A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102255580B1 (ko) 2020-07-14 2021-05-25 (주)지에프씨생명과학 마테 추출물 및 트라넥삼산의 혼합물을 유효성분으로 포함하는 화장료 조성물
WO2023077339A1 (zh) * 2021-11-04 2023-05-11 深圳市维琪科技股份有限公司 一种四肽衍生物及其美容组合物或药用组合物和用途
KR20240032203A (ko) * 2022-08-30 2024-03-12 주식회사 바이오셀트란 미백용 복합 펩타이드 및 이를 함유하는 화장료 조성물

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05170637A (ja) * 1991-12-25 1993-07-09 Narisu Keshohin:Kk 美白化粧料
JPH0672846A (ja) * 1992-08-31 1994-03-15 Shiseido Co Ltd 皮膚外用剤
JPH06345797A (ja) * 1993-06-11 1994-12-20 Yakult Honsha Co Ltd ジペプチド及びこれを含有する化粧料
KR20040060157A (ko) * 2002-12-30 2004-07-06 주식회사 코리아나화장품 트라넥사믹산을 포함하는 피부 미백용 화장료 조성물
KR20100092150A (ko) * 2009-02-12 2010-08-20 주식회사 웰스킨 다이펩타이드를 포함하는 피부 미백용 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69316681T2 (de) * 1992-08-27 1998-05-14 Shiseido Co Ltd Äusserliche, auf der Haut anzuwendende Depigmentierungsmittel enthaltende Zusammensetzung
JPH07165556A (ja) * 1993-12-09 1995-06-27 Shiseido Co Ltd 皮膚外用剤
ATE464041T1 (de) * 2002-12-27 2010-04-15 Daiichi Sankyo Healthcare Co Zusammensetzung zur hautaufhellung
JP2013523721A (ja) * 2010-03-31 2013-06-17 株式會社アモーレパシフィック メラニン色素生成抑制剤及びこれを含有する化粧料組成物
KR101167285B1 (ko) * 2011-11-18 2012-07-23 에이앤펩주식회사 피부 미백 활성을 갖는 나이아신-펩타이드 및 그의 용도

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05170637A (ja) * 1991-12-25 1993-07-09 Narisu Keshohin:Kk 美白化粧料
JPH0672846A (ja) * 1992-08-31 1994-03-15 Shiseido Co Ltd 皮膚外用剤
JPH06345797A (ja) * 1993-06-11 1994-12-20 Yakult Honsha Co Ltd ジペプチド及びこれを含有する化粧料
KR20040060157A (ko) * 2002-12-30 2004-07-06 주식회사 코리아나화장품 트라넥사믹산을 포함하는 피부 미백용 화장료 조성물
KR20100092150A (ko) * 2009-02-12 2010-08-20 주식회사 웰스킨 다이펩타이드를 포함하는 피부 미백용 조성물

Also Published As

Publication number Publication date
CN109311938A (zh) 2019-02-05
KR101848887B1 (ko) 2018-04-13
KR20180002970A (ko) 2018-01-09
CN109311938B (zh) 2022-10-11
US20190380943A1 (en) 2019-12-19
WO2018004281A2 (ko) 2018-01-04
US10532018B2 (en) 2020-01-14

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