WO2017213401A3 - 회전형 세포배양장치 - Google Patents

회전형 세포배양장치 Download PDF

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Publication number
WO2017213401A3
WO2017213401A3 PCT/KR2017/005869 KR2017005869W WO2017213401A3 WO 2017213401 A3 WO2017213401 A3 WO 2017213401A3 KR 2017005869 W KR2017005869 W KR 2017005869W WO 2017213401 A3 WO2017213401 A3 WO 2017213401A3
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WO
WIPO (PCT)
Prior art keywords
fixed shaft
gas supply
gas
culture container
cell culture
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PCT/KR2017/005869
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English (en)
French (fr)
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WO2017213401A2 (ko
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정재준
최문식
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주식회사 아리바이오
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Publication of WO2017213401A2 publication Critical patent/WO2017213401A2/ko
Publication of WO2017213401A3 publication Critical patent/WO2017213401A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/10—Rotating vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/24—Recirculation of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/04—Tissue, human, animal or plant cell, or virus culture apparatus with means providing thin layers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

본 발명에 따른 회전형 세포배양장치(1000)는 가스공급로(841)와 가스배출로(861)를 가지는 가스공급 및 배출부재(850)가 일단에 설치된 것으로서 회전하지 않고 고정된 고정축(800)을 가진다. 배양액이 담겨지는 배양통(100)의 내부를 가로질러 상기 고정축(800)이 설치되어 이를 중심으로 상기 배양통(100)은 회전을 이루게 된다. 상기 배양통(100)을 상기 고정축(800)을 중심으로 강제로 회전시키는 회전수단(M)(210)(220)이 제공된다. 상기 배양통(100)의 내부에는 상기 고정축(800)의 가스공급 및 배출부재(850)의 가스배출로(861)와 연통하는 가스포집수단(580)이 설치된다. 상기 고정축(800)은 상기 가스공급로(841)와 연통하는 중공부(838)를 가지고 그 표면은 다공질이다. 상기 가스공급로(841)로 공기를 공급하는 공기압축기(40)가 제공된다.
PCT/KR2017/005869 2016-06-09 2017-06-05 회전형 세포배양장치 WO2017213401A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020160071705A KR101754751B1 (ko) 2016-06-09 2016-06-09 회전형 세포배양장치
KR10-2016-0071705 2016-06-09

Publications (2)

Publication Number Publication Date
WO2017213401A2 WO2017213401A2 (ko) 2017-12-14
WO2017213401A3 true WO2017213401A3 (ko) 2018-02-01

Family

ID=59443265

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2017/005869 WO2017213401A2 (ko) 2016-06-09 2017-06-05 회전형 세포배양장치

Country Status (2)

Country Link
KR (1) KR101754751B1 (ko)
WO (1) WO2017213401A2 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101754751B1 (ko) * 2016-06-09 2017-07-20 주식회사 아리바이오 회전형 세포배양장치
KR102087710B1 (ko) * 2019-05-22 2020-03-11 주식회사 아리바이오 회전형 세포배양 장치를 이용한 nk 세포 활성과 증식 향상의 배양 방법 및 이에 생산된 nk 배양액의 용도
CN112646692A (zh) * 2020-12-11 2021-04-13 中国人民解放军陆军军医大学第二附属医院 一种肠道菌液培养装置
CN114134035A (zh) * 2021-12-10 2022-03-04 普瑞特机械制造股份有限公司 一种可用于筛选曲粉的旋转加热设备

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100542906B1 (ko) * 2004-12-06 2006-01-11 현대엔지니어링 주식회사 퇴비화용 회전 발효반응기의 공기 급배기장치
KR20090056667A (ko) * 2007-11-30 2009-06-03 코아스템(주) 세포배양장치 및 이를 구비한 대용량 자동화 세포배양기
KR20100035434A (ko) * 2008-09-26 2010-04-05 코아스템(주) 실린지 형상의 배양관 및 이를 이용한 세포배양기
KR20120066282A (ko) * 2010-12-14 2012-06-22 세종공업 주식회사 미세조류 배양장치
KR101754751B1 (ko) * 2016-06-09 2017-07-20 주식회사 아리바이오 회전형 세포배양장치

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020088848A (ko) 2001-05-21 2002-11-29 (주)코아바이오텍 세포배양관 및 이를 이용한 대량 세포배양기

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100542906B1 (ko) * 2004-12-06 2006-01-11 현대엔지니어링 주식회사 퇴비화용 회전 발효반응기의 공기 급배기장치
KR20090056667A (ko) * 2007-11-30 2009-06-03 코아스템(주) 세포배양장치 및 이를 구비한 대용량 자동화 세포배양기
KR20100035434A (ko) * 2008-09-26 2010-04-05 코아스템(주) 실린지 형상의 배양관 및 이를 이용한 세포배양기
KR20120066282A (ko) * 2010-12-14 2012-06-22 세종공업 주식회사 미세조류 배양장치
KR101754751B1 (ko) * 2016-06-09 2017-07-20 주식회사 아리바이오 회전형 세포배양장치

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KR101754751B1 (ko) 2017-07-20
WO2017213401A2 (ko) 2017-12-14

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