WO2017096755A1 - 一种治疗兔子胀气腹泻的复方中药及其使用方法 - Google Patents

一种治疗兔子胀气腹泻的复方中药及其使用方法 Download PDF

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WO2017096755A1
WO2017096755A1 PCT/CN2016/081712 CN2016081712W WO2017096755A1 WO 2017096755 A1 WO2017096755 A1 WO 2017096755A1 CN 2016081712 W CN2016081712 W CN 2016081712W WO 2017096755 A1 WO2017096755 A1 WO 2017096755A1
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chinese medicine
diarrhea
rabbit
compound chinese
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PCT/CN2016/081712
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English (en)
French (fr)
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黄安全
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四川行之智汇知识产权运营有限公司
蓬溪发联农牧有限公司
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A61K36/575—Magnolia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage

Definitions

  • the invention belongs to the technical field of poultry medicine, and particularly relates to a compound Chinese medicine for treating flatulence and diarrhea in rabbits and a using method thereof.
  • rabbits In the breeding process of rabbits, rabbits often experience symptoms such as diarrhea (or diarrhea), constipation, flatulence, colds and rhinitis. If left untreated, the condition will become more and more serious, and eventually the rabbit will die.
  • rabbit flatulence is a disease that is often encountered in rabbit breeding. There are many reasons for rabbits to flatulence. When rabbits suffer from insufficient fiber intake, dehydration, and urgency, intestinal slowing will cause food or foreign matter to accumulate. In the stomach or intestine, obstruction occurs. If no treatment is taken, the blockage will become more and more serious, the peristalsis will be completely stagnant, and the stomach or intestines will be severely damaged.
  • rabbit diarrhea There are many reasons for rabbit diarrhea, such as improper feeding management, low dietary fiber, low feeding, irregular feeding, toxic substances, cold in the abdomen, etc.
  • improper feeding management low dietary fiber, low feeding, irregular feeding, toxic substances, cold in the abdomen, etc.
  • the feces are mostly watery or paste-like, and the feces are mixed with undigested food. Scraps, steam drums or mucus, the rabbit is severely dehydrated and quickly loses weight.
  • the object of the present invention is to provide a compound Chinese medicine capable of simultaneously treating flatulence and diarrhea, and a method for using the compound Chinese medicine, and a traditional Chinese medicine formula for treating flatulence and diarrhea in rabbits, in order to solve the problem of prone to flatulence and diarrhea during rabbit breeding.
  • the drug can achieve the effect of appetizing and strengthening the spleen and promoting digestion.
  • a compound Chinese medicine for treating flatulence and diarrhea in rabbits wherein the weight fraction of each raw material of the compound Chinese medicine is: 1-3 parts of Atractylodes, 2-5 parts of woody, 1-3 parts of Magnolia, 2-3 parts of medlar, 1-2 parts of rhubarb, 2-4 parts of hawthorn, 2-3 parts of Jianqu, 1-2 parts of fried radish, 0.5-1 parts of cypress.
  • the weight fraction of each raw material of the compound Chinese medicine is: 1-2 parts of Atractylodes, 2-3 parts of woody, 1-2 parts of Magnolia, 2-3 parts of medlar, 1-2 parts of rhubarb, hawthorn 2-4 parts, 2-3 pieces of Jianqu, 1-2 parts of fried radish, 0.5 parts of cypress.
  • the weight fraction of each raw material of the compound Chinese medicine is: 1 part of Atractylodes, 3 parts of woody, 2 parts of Magnolia, and tamping 2-3 parts, 1 part of rhubarb, 3 parts of hawthorn, 2-3 parts of Jianqu, 1-2 parts of fried radish, 0.5 parts of cypress.
  • the dosage form of the compound Chinese medicine is a powder.
  • the invention also provides a method for using the above compound Chinese medicine, the technical scheme is:
  • Each raw material medicine is separately pulverized, pulverized, sieved with a 50-100 mesh sieve, and then uniformly mixed according to the mixing ratio of the compound Chinese medicine, and then mixed into the rabbit food material according to the medicinal amount of 3-5 grams of the powder compound of each rabbit. 1 time in the morning and evening, continuous feeding for 5-7 days.
  • the invention also provides another method for using the above compound Chinese medicine, the technical scheme is:
  • Each raw material medicine is separately pulverized, pulverized, sieved with a 50-100 mesh sieve, and then uniformly mixed according to the mixing ratio of the compound Chinese medicine, and then mixed into the rabbit drinking water according to the medicinal amount of 3-5 grams of the powder compound of each rabbit. Feeding, 1 time in the morning and evening, continuous feeding for 5-7 days.
  • the invention relates to a compound traditional Chinese medicine for treating flatulence and diarrhea in rabbits and a method for using the same.
  • the distribution area in the gastrointestinal tract is large, the absorption is fast, the diarrhea is fast, and at the same time, the gastrointestinal motility function can be adjusted, and the relaxation state is Smooth muscle has excitatory effect, accelerates intestinal peristalsis, helps digestion, promotes rabbit growth, abandons dependence on antibiotics and other drugs, enhances rabbit's constitution, and has the dual effect of simultaneously treating flatulence and diarrhea; compound Chinese medicine powder can be mixed into rabbit Feeding the rabbits in the food or in the water is easier to absorb.
  • Embodiment 1 is a diagrammatic representation of Embodiment 1:
  • the raw materials of the compound Chinese medicine were crushed and sieved with a 100 mesh sieve, then 100 g of Atractylodes, 300 g of woody, 200 g of Magnolia, 200 g of eucalyptus, 100 g of rhubarb, 300 g of hawthorn, 300 g of Jianqu, 100 g of roasted radish, cypress 50g was weighed and mixed evenly. Stir in the rabbit foodstuff according to the dosage of 5g of powder in each rabbit, and feed it once in the morning and evening for 5 days.
  • Embodiment 2 is a diagrammatic representation of Embodiment 1:
  • the raw materials of the compound Chinese medicine were crushed and sieved with a 100 mesh sieve, then 100 g of Atractylodes, 300 g of woody, 200 g of Magnolia, 300 g of medlar, 100 g of rhubarb, 300 g of hawthorn, 200 g of Jianqu, 200 g of fried radish, cypress 50g was weighed and mixed evenly. Stir in the rabbit foodstuff according to the dosage of the powder of 3 grams of each rabbit, and feed it once in the morning and evening for 7 days.
  • Embodiment 3 is a diagrammatic representation of Embodiment 3
  • the raw materials of the compound Chinese medicine were crushed and sieved with a 50 mesh sieve, and then 200 g of atractylodes, 200 g of woody, Magnolia 100g, citrus 250g, rhubarb 200g, hawthorn 200g, Jianqu 250g, fried radish 150g, cypress fruit 50g weighed, mixed evenly, according to the amount of 5 grams of each rabbit in the powder compound mixed into the rabbit food feed 1 time in the morning and evening, continuous feeding for 5 days.
  • Embodiment 4 is a diagrammatic representation of Embodiment 4:
  • the raw materials of the compound Chinese medicine were crushed and sieved with a 100 mesh sieve, then 150 g of Atractylodes, 200 g of woody, 100 g of Magnolia, 300 g of medlar, 200 g of rhubarb, 400 g of hawthorn, 200 g of Jianqu, 100 g of roasted radish, cypress 50g was weighed, mixed evenly, and then mixed with rabbit foodstuffs according to the dosage of 4 grams of powder in each rabbit, and fed once in the morning and evening, and fed continuously for 6 days.
  • Embodiment 5 is a diagrammatic representation of Embodiment 5:
  • the raw materials of the compound Chinese medicine were crushed and sieved with 50 mesh sieve, then according to Atractylodes 300g, woody 500g, Magnolia 300g, medlar 200g, rhubarb 150g, hawthorn 300g, Jianqu 300g, fried radish 100g, cypress After weighing 100g, mix well, and mix it into rabbit foodstuff according to the dosage of 5g of powder in each rabbit, and feed it once in the morning and evening for 5 days.
  • Each raw material of the compound Chinese medicine is crushed and sieved with 100 mesh sieve, then according to Atractylodes 300g, woody 400g, Magnolia 300g, medlar 250g, rhubarb 100g, hawthorn 350g, Jianqu 200g, fried radish 200g, cypress 70g was weighed and mixed evenly.
  • 140 rabbits were selected for experimental research. Of the 140 rabbits, 70 rabbits were in a diarrhea state, and another 70 rabbits had flatulence, with 10 diarrhea rabbits and 10 flatulent rabbits. For one group, 140 rabbits were divided into 7 groups, 6 of which were fed according to the compound Chinese medicines of 6 examples, and the other group was fed without drugs, and the rats were fed normally for one week to observe the growth of the rabbits.

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Abstract

公开了一种治疗兔子胀气腹泻的复方中药及其制备方法，该复方中药各原料药的重量份数为：苍术1-3份，木香2-5份，厚朴1-3份，枳实2-3份，大黄1-2份，山楂2-4份，建曲2-3份，炒萝卜子1-2份，柏树果0.5-1份。该复方中药的制备方法包括将各原料药分别粉碎，粉碎后用50-100目筛筛粒，然后按照所述复方中药的混合比例均匀混合。

Description

一种治疗兔子胀气腹泻的复方中药及其使用方法 技术领域
本发明属于家禽用药技术领域，具体涉及一种治疗兔子胀气腹泻的复方中药及其使用方法。
背景技术
在兔子的养殖过程中，经常会遇到兔子拉稀(或腹泻)、便秘、胀气、感冒和鼻炎等症状，如果不及时治疗，病情会越来越严重，最后导致兔子死亡。
其中，兔子胀气是兔子饲养过程中经常会遇到的疾病，导致兔子胀气的原因很多，当兔子遭遇粗纤维摄入不足、脱水、紧迫等因素时，肠道蠕动变慢会使食物或异物堆积在胃或肠道中，阻塞产生。若不采取治疗措施，阻塞会越来越严重，蠕动会完全停滞，胃或肠道遭到严重破坏。
兔子拉稀的原因很多，例如饲养管理不当，日粮粗纤维过低，不定时喂食，含有毒物质，腹部受凉等，腹泻时，粪多为水样或者糊状，粪中混有未消化的食物残屑，有汽包或黏液，兔子严重脱水，迅速消瘦。
由于导致兔子胀气和腹泻的原因很多，根据不同的病因采取不同的治疗手段以及治疗药物，因此导致兔子胀气和兔子腹泻的治疗非常困难，同时还存在的乱用药物，尤其是抗生素的问题，使得兔子体质变弱，更容易生病，治疗更加困难。
发明内容
本发明的目的在于：针对兔子养殖过程中容易出现胀气和腹泻的问题，提供一种能同时治疗胀气及腹泻的复方中药，以及该复方中药的使用方法，采用中药配方作为治疗兔子胀气及腹泻的药物，能达到开胃健脾、促进消化的效果。
为了实现上述目的，本发明采用的技术方案为：
一种治疗兔子胀气腹泻的复方中药，所述复方中药各原料药的重量份数为：苍术1-3份，木香2-5份，厚朴1-3份，枳实2-3份，大黄1-2份，山楂2-4份，建曲2-3份，炒萝卜子1-2份，柏树果0.5-1份。
优选地，所述复方中药各原料药的重量份数为：苍术1-2份，木香2-3份，厚朴1-2份，枳实2-3份，大黄1-2份，山楂2-4份，建曲2-3份，炒萝卜子1-2份，柏树果0.5份。
优选地，所述复方中药各原料药的重量份数为：苍术1份，木香3份，厚朴2份，枳实 2-3份，大黄1份，山楂3份，建曲2-3份，炒萝卜子1-2份，柏树果0.5份。
优选地，复方中药的剂型为粉剂。
本发明还提供上述复方中药的使用方法，技术方案为：
将各原料药分别粉碎，粉碎后用50-100目筛筛粒，然后按照所述复方中药的混合比例均匀混合，然后按照每只兔子3-5克的粉剂复方中药用量拌入兔子食料中喂食，早晚各1次，连续喂食5-7天。
本发明还提供上述复方中药的另一种使用方法，技术方案为：
将各原料药分别粉碎，粉碎后用50-100目筛筛粒，然后按照所述复方中药的混合比例均匀混合，然后按照每只兔子3-5克的粉剂复方中药用量拌入兔子饮用水中喂食，早晚各1次，连续喂食5-7天。
由于采用了上述技术方案，本发明的有益效果是：
本发明的一种治疗兔子胀气腹泻的复方中药及其使用方法，兔子服用后，在肠胃的分布面积大，吸收快，止泻快，同时能够对胃肠运动功能具有调节作用，对松弛状态的平滑肌有兴奋作用，加快肠道蠕动，助消化，促进兔子的生长，摒弃了对抗生素等药物的依赖，增强兔子的体质，具有同时治疗胀气和腹泻的双重功效；复方中药的粉剂可拌入兔子食料或者引用水中，喂食兔子，吸收更容易。
具体实施方式
下面结合具体的实施方式对本发明作进一步的说明。
实施例一：
取复方中药的各原料药分别粉碎后用100目筛筛粒，然后按照苍术100g，木香300g，厚朴200g，枳实200g，大黄100g，山楂300g，建曲300g，炒萝卜子100g，柏树果50g称取，混合均匀后，按照每只兔子5克的粉剂复方中药用量拌入兔子食料中喂食，早晚各1次，连续喂食5天。
实施例二：
取复方中药的各原料药分别粉碎后用100目筛筛粒，然后按照苍术100g，木香300g，厚朴200g，枳实300g，大黄100g，山楂300g，建曲200g，炒萝卜子200g，柏树果50g称取，混合均匀后，按照每只兔子3克的粉剂复方中药用量拌入兔子食料中喂食，早晚各1次，连续喂食7天。
实施例三：
取复方中药的各原料药分别粉碎后用50目筛筛粒，然后按照苍术200g，木香200g， 厚朴100g，枳实250g，大黄200g，山楂200g，建曲250g，炒萝卜子150g，柏树果50g称取，混合均匀后，按照每只兔子5克的粉剂复方中药用量拌入兔子食料中喂食，早晚各1次，连续喂食5天。
实施例四：
取复方中药的各原料药分别粉碎后用100目筛筛粒，然后按照苍术150g，木香200g，厚朴100g，枳实300g，大黄200g，山楂400g，建曲200g，炒萝卜子100g，柏树果50g称取，混合均匀后，按照每只兔子4克的粉剂复方中药用量拌入兔子食料中喂食，早晚各1次，连续喂食6天。
实施例五：
取复方中药的各原料药分别粉碎后用50目筛筛粒，然后按照苍术300g，木香500g，厚朴300g，枳实200g，大黄150g，山楂300g，建曲300g，炒萝卜子100g，柏树果100g称取，混合均匀后，按照每只兔子5克的粉剂复方中药用量拌入兔子食料中喂食，早晚各1次，连续喂食5天。
实施例六：
取复方中药的各原料药分别粉碎后用100目筛筛粒，然后按照苍术300g，木香400g，厚朴300g，枳实250g，大黄100g，山楂350g，建曲200g，炒萝卜子200g，柏树果70g称取，混合均匀后，按照每只兔子5克的粉剂复方中药用量拌入兔子食料中喂食，早晚各1次，连续喂食7天。
为了检测复方中药的治疗效果，现选用140兔子进行实验研究，140只兔子中，70只兔子为正处于拉稀状态，另外70只兔子存在胀气现象，以10只拉稀的兔子和10只胀气的兔子为一组，将140只兔子分为7组，其中6组按照6个实施例的复方中药分别进行喂食，另外1组不喂药，正常喂食，为期一周，观察兔子的生长情况。
表1兔子健康情况实验研究统计表
Figure PCTCN2016081712-appb-000001
Figure PCTCN2016081712-appb-000002
实验结果表明，本发明的复方中药具有极为明显的治疗效果，并且能同时治疗兔子的胀气和腹泻。

Claims (6)

  1. 一种治疗兔子胀气腹泻的复方中药，其特征在于，所述复方中药各原料药的重量份数为：苍术1-3份，木香2-5份，厚朴1-3份，枳实2-3份，大黄1-2份，山楂2-4份，建曲2-3份，炒萝卜子1-2份，柏树果0.5-1份。
  2. 根据权利要求1所述的治疗兔子胀气腹泻的复方中药，其特征在于，所述复方中药各原料药的重量份数为：苍术1-2份，木香2-3份，厚朴1-2份，枳实2-3份，大黄1-2份，山楂2-4份，建曲2-3份，炒萝卜子1-2份，柏树果0.5份。
  3. 根据权利要求2所述的治疗兔子胀气腹泻的复方中药，其特征在于，所述复方中药各原料药的重量份数为：苍术1份，木香3份，厚朴2份，枳实2-3份，大黄1份，山楂3份，建曲2-3份，炒萝卜子1-2份，柏树果0.5份。
  4. 根据权利要求1-3任意一项所述的治疗兔子胀气及腹泻的复方中药，其特征在于，复方中药的剂型为粉剂。
  5. 根据权利要求1-3任意一项所述的治疗兔子胀气腹泻的复方中药的使用方法，其特征在于，将各原料药分别粉碎，粉碎后用50-100目筛筛粒，然后按照所述复方中药的混合比例均匀混合，然后按照每只兔子3-5克的粉剂复方中药用量拌入兔子食料中喂食，早晚各1次，连续喂食5-7天。
  6. 根据权利要求1-3任意一项所述的治疗兔子胀气腹泻的复方中药的使用方法，其特征在于，将各原料药分别粉碎，粉碎后用50-100目筛筛粒，然后按照所述复方中药的混合比例均匀混合，然后按照每只兔子3-5克的粉剂复方中药用量拌入兔子饮用水中喂食，早晚各1次，连续喂食5-7天。
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