WO2017055503A1 - Multifokale linse und verfahren zu deren herstellung - Google Patents
Multifokale linse und verfahren zu deren herstellung Download PDFInfo
- Publication number
- WO2017055503A1 WO2017055503A1 PCT/EP2016/073349 EP2016073349W WO2017055503A1 WO 2017055503 A1 WO2017055503 A1 WO 2017055503A1 EP 2016073349 W EP2016073349 W EP 2016073349W WO 2017055503 A1 WO2017055503 A1 WO 2017055503A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- lens
- diffractive
- diffractive structure
- focus
- structures
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1616—Pseudo-accommodative, e.g. multifocal or enabling monovision
- A61F2/1618—Multifocal lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1637—Correcting aberrations caused by inhomogeneities; correcting intrinsic aberrations, e.g. of the cornea, of the surface of the natural lens, aspheric, cylindrical, toric lenses
- A61F2/164—Aspheric lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1654—Diffractive lenses
- A61F2/1656—Fresnel lenses, prisms or plates
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/041—Contact lenses for the eyes bifocal; multifocal
- G02C7/044—Annular configuration, e.g. pupil tuned
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C2202/00—Generic optical aspects applicable to one or more of the subgroups of G02C7/00
- G02C2202/20—Diffractive and Fresnel lenses or lens portions
Definitions
- Multifocal lens and method of making the same
- the present invention relates to a multifocal lens, in particular an intraocular or contact lens, with a refractive focus and a first and a second diffractive structure, which at least partially overlap.
- the invention relates to a method for producing such a multifocal lens.
- Multifocal intraocular or contact lenses i.
- Lenses with multiple focal points e.g. can be used for near and far vision (bi-focal) or near, intermediate and distance (trifocal), have been known for several decades and use a variety of diffractive structures on a refractive base lens, in addition to the refractive focus one or more diffractive foci to accomplish .
- the objective is achieved with a lens of the initially mentioned type, in which the two diffractive structures are different, and wherein a first-order focus of the first diffractive structure coincides with a first-order focus of the second diffractive structure.
- the computation of the superimposed diffractive structure can be considerably simplified, since the structures to be superimposed each have a profile with equal period lengths. Adjustments of the structures for determining an optimal intensity distribution during the calculation can thus be carried out particularly easily.
- the two diffractive structures have different intensity distributions, whereby an individual mixture of intensity ratios is possible.
- a particularly advantageous embodiment of the invention is characterized in that the first diffractive structure has an intensity distribution which is asymmetrical about the refractive focus and the second diffractive structure has an intensity distribution substantially symmetrical about the refractive focus.
- the superposition of these two diffractive structures creates a lens whose focal points which can be used for near, intermediate and distance vision have a higher intensity component than known in the prior art.
- diffractive foci of "positive" order are defined as those lying between the lens and its refractive focus and "negative" order diffractive foci as those on the side of the lens facing away from the lens refractive focus lie.
- the focal point of the first positive order of the diffractive structures corresponds to a distance for the intermediary view and the focal point of the second positive order of the diffractive structures to a distance for the near view.
- the respective negative focal points of the diffractive structures are only imaged behind the retina of the user of the lens, which is why they can not be used by the user and contribute to a deterioration of the image quality.
- the refractive focus is used for near vision
- the focal point of the first negative order of the superposition structure is at a distance for the intermediary
- the focal point of the second negative order of the heterodyne structure corresponds to a distance for far vision.
- the positive orders of the diffractive structures are difficult to use because they are located in front of the near-vision focal point, and the orders of the third negative order are not usable, since they are only focused behind the retina.
- the intensity components of the positive orders are mapped here to the zeroth (refractory), negative first and negative second order, which in comparison to the prior art again results in a higher luminous efficacy in the usable focal points and thus a more color intensive and high-contrast image results.
- the profiles of the two diffractive structures have an equal period length, wherein the profile of the first diffractive structure is monotonically increasing within the period and the profile of the second diffractive structure is minimum in the first half of the period and second in the second half of the period Maximum has.
- the first diffractive structure ie the structure with the asymmetrical intensity distribution
- the second diffractive structure ie the structure with the substantially symmetrical intensity distribution
- This profile profiles can be used, their behavior is well known and also allow easy production.
- At least one of the profiles may have rounded or chamfered flanks.
- the two diffractive structures overlap only in a central region of the lens.
- the lens outside the central area may not have any diffractive structure at all. If the pupil becomes larger, for example at low incidence of light, then the influence of the non-central area resp. of the refractive portion for the distance view larger, so that at such pupil sizes the intensity distribution includes only the distance view.
- the lens may also have only one of the two diffractive structures outside the central region, as a result of which, for example, the near and far vision or the intermediate and long-distance vision can be designed to be the largest for wide pupils.
- the two diffractive structures are preferably apodized in the radial direction of the lens, preferably with different strengths.
- the intensity distributions can be adjusted as desired to the desired pupil size.
- the lens of the invention can basically be used in any optical devices, but it is particularly suitable as a multifocal contact or intraocular lens.
- the invention also provides a method for producing the lens presented here.
- the method comprises the following steps:
- incorporating the overlay structure into the lens blank to make the multifocal lens.
- the step of incorporating the overlay structure in the lens blank is preferably carried out by turning, which allows a particularly precise production of the multifocal lens.
- the method comprises the following steps:
- a mold blank having the overlay structure i. a "negative mold” created by, for example, turning or milling
- the lens may be cast, pressed, tested or otherwise formed by the negative mold.
- the contacting preferably takes place by casting the lens material onto the blank mold and curing the lens material.
- the lens material can in this case solidify by itself or be cured by means of light or heat treatment.
- the first diffractive structure has an intensity distribution which is asymmetric about the refractive focus
- the second diffractive structure has an intensity distribution substantially symmetrical about the refractive focus
- Fig. 1 shows the lens according to the invention in a schematic plan view
- FIG. 2 the lens of FIG. 1 in a schematic side view
- FIG. 3 shows profiles of a first and a second diffractive structure as well as the profile of a superimposition structure for the lens from FIG. 1 resulting from the superposition of the first and second structures.
- FIG. 1 ;
- FIG. 4 the lens of FIG. 1 with the overlay structure of FIG. 3 in an enlarged half section;
- FIG. 5 shows the intensity distribution of a first diffractive structure of FIG. 3 equipped lens;
- FIG. 6 shows the intensity distribution of a second diffractive structure of FIG. 3 equipped lens
- Fig. 7 shows the intensity distribution of the erfindungssuren
- Fig. 8 shows a first embodiment of the method according to the invention for producing the lens of FIG. 1 in a schematic block diagram
- Fig. 9 shows a second embodiment of the invention
- Fig. 10 shows a comparison of the intensity distribution of the lens according to the invention with a lens according to the prior art.
- the Fig. 1 and 2 show a lens 1 having a front side 2, a back side 3 and an optical axis 4.
- the lens 1 has a central zone Z ⁇ and two annular zones Z 2l Z 3 , which will be explained in more detail later.
- the described lens 1 is used as an intraocular lens or contact lens, but can also be used in optical devices.
- the lens 1 has a refractive focus F r lying on the optical axis 4, which can be used for the distance or near vision as described below and is also referred to below as the zero-order focal point.
- F r refractive focus
- 3 of the lens 1 is a dif frine Structure 5 incorporated, see FIG. 4, to adapt the lens 1 for both near and intermediate and distance vision.
- the diffractive foci F g _, F 9i2 are used as foci of positive first resp. second order of the diffractive structure denote 5 and lie on the optical axis 4 between the lens 1 and the refractive focus F r .
- the diffractive foci F 9i " 1; F g are used as foci of negative first resp. second order of the diffractive structure denoted 5 and lie on the side facing away from the lens 1 of the refractive focus F r .
- the intensity distribution attributed to the respective focal points F g , i should not be symmetrical.
- the intensity distribution attributed to the respective focal points F g , i should not be symmetrical.
- the first dif fra ⁇ ive structure 6 has a grating period pi (r), which depends on the radius r, exactly - of r 2 . If the structure 6 is plotted as an abscissa scale over r 2 , the period ⁇ > occurs . in equidistant repetitions above the abscissa.
- the first diffractive structure 6 has an asymmetrical intensity distribution about the refractive focus F r in its diffractive focal points Fi,, see later FIG. 5, and has for this purpose a profile 8 applied to the squared radius r 2, asymmetrically rising and falling edges 9, 10, wherein one of the flanks 9, 10 may be perpendicular.
- Fig. 3 shows the first diffractive structure 6 with a sawtooth form, but alternatively it could also have an echelette or kinoform.
- the grating period pi (r) determines the distance of the foci F i generated by the first diffractive structure 6. from the refractive focus F r .
- Fig. 3 shows in the middle diagram the profile of the second diffractive structure 7 (abscissa: radius r 2 [mm 2 ]; ordinate: profile depth T [mm]).
- the second diffractive structure 7 has a grating period p 2 (r) which depends on the radius r, more precisely r 2 . If the structure 7 is plotted as abscissa scale via r 2 , the period p 2 occurs in equidistant repetitions over the abscissa.
- the second dif-fractional structure 7 has a substantially symmetrical intensity about the refractive focus F r. Distribution in their diffractive foci F 2 , i, as later with reference to FIG. 5 explained in more detail.
- the structure 7 has a profile with respect to one another, plotted over the square radius r 2 , and essentially flanking and descending flanks 12, 13, which are preferably perpendicular.
- the term "substantially symmetrical" includes in each case slight deviations from the symmetry.
- Fig. 3 shows the second diffractive structure 7 as a binary structure, ie with a rectangular shape. Alternatively, however, it could also have a trapezoidal or sinusoidal shape, for example.
- the grating period p 2 (r) determines the distance of the focal points F 2 generated by the second diffractive structure 7, ⁇ from the refractive focus F r .
- FIG. 5 shows the intensity distribution of a lens to which only a first diffractive structure 6 according to the uppermost diagram of FIG. 3 is plotted (abscissa: distance D from the lens [mm]; ordinate: relative intensity I [1]). As shown, the intensity distribution of the diffractive foci F 1; i is asymmetric about the refractive focus.
- FIG. 6 shows the intensity distribution of a lens 1, to which only a second diffractive structure 7 according to the middle diagram of FIG. 3 is plotted (abscissa: distance D from the lens [mm]; ordinate: relative intensity I [1]).
- the focal points F 2 i, F:; , 2 , ... positive order a substantially equal intensity component to the focal points F 2 , -i, F 2i _ 2 , ... negative order.
- the grating periods pi (r) and p 2 (r) are the same, so that according to FIGS. 5 and 6, the first positive focus Fi , the first diffractive structure 6 is located at a distance from the refractive focus F r , which corresponds to the distance of the first positive focus F 2 , i of the second diffractive structure 7.
- the composite, "superimposed" diffractive structure 5 is obtained by additive superimposition of the two structures 6, 7 (abscissa: radius r 2 [mm 2 ]; ordinate: profile depth T [mm].)
- the superimposed diffractive structure 5 has a Profile 14 with rising and falling flanks 15, 16, so that the profile 14 of the diffractive structure 5 is monotonically increasing substantially within one period
- the diffractive structure 5 with the profile 14 is applied to one of the sides 2, 3 of the lens 1 See Figure 4.
- the profiles 8, 11, 14 may have rounded or chamfered flanks 9, 10, 12, 13, 15, 16.
- the profile 8 of the first diffractive structure 6 increases monotonically within the period pi (r) and the profile 11 of the second diffractive structure 7 has a minimum in the first half of the period p 2 (r) and in the second half Half of the period a maximum.
- the profile 14 of the superimposed diffractive structure 5 increases monotonically within the period pi (r), p 2 (r) and thus has only a maximum within this period.
- the second diffractive structure 7 may be the maximum also in the first half of the period p :: (r) and have the minimum in the second half of the period, which then leads to a superimposed dif frepte structure 5 with two maxima per period.
- the first-mentioned variant with only one maximum per period is to be preferred.
- FIG. 7 shows the intensity distribution of the lens 1, into which the diffractive structure 5 is composed of the added or superimposed structures 6, 7 is incorporated (abscissa: distance D from the lens [mm]; ordinate: relative intensity I [1]).
- the refractive focus F r is used here for the distance vision
- the first positive dif - fractive focus F 9il corresponds in position to the focal points Fi. i, F 2, i of the first (positive) order of the diffractive structures 6, 7 and is used for the intermediate view
- the second positive dif-fractive focus F gi2 corresponds in position to the foci F 1 , F 2.2 second ( positive) order of dif-fractional structures 6, 7 and is used for near vision.
- the slopes of the flanks 9, 10, 12, 13 could be reversed by 1 s, whereby, for example, the refractive focus F r for the near vision and the first-order diffractive foci F li ⁇ , F 2 , i or. second order Fi. 2, F 2i2 respectively for the intermediary. Distance vision could be used.
- the two structures 6, 7 can either be applied to the entire surface of the side 2, 3 of the lens 1 for 1 second, or only zonally, as shown in FIG. 1 shown.
- the combined structure 5 can be applied only in the innermost zone Zi, ie in the central region, of the lens 1.
- Only one of the two structures 6, 7 can be applied to a surrounding annular zone Z 2 , and none of the structures 5, 6, 7 can be applied in an outermost annular zone Z 3.
- an intensity distribution dependent on the pupil size is achieved, the weighting of the intensity at the refractive focus F r increases with increasing pupil size.
- this effect can be achieved by apodization of the structures 5, 6, 7. This means that the depth T of the profiles 8, 11, 14 of the structures 5, 6, 7 decreases with increasing lens radius r (not shown in FIG. 3).
- the Fig. 8 and 9 show two variants of the method for producing the multifocal lens 1.
- the diffractive structure 5 also referred to as "overlay structure” 5
- the first diffractive structure 6, which has a refractive focus F r has asymmetrical intensity distribution
- the second diffractive structure 7, which has an intensity distribution substantially symmetrical about the refractive focus F r is superimposed, eg added.
- the structures 6, 7 can be made available to the arithmetic unit 17 by means of memories 18, 19 or the arithmetic unit 17 itself be calculated or determined.
- Fig. 8 shows a first variant of the manufacturing method in which the overlay structure 5 calculated in the arithmetic unit 17 is worked into a lens blank 20, for example, by machining such as turning in a lathe 21 so as to manufacture the multifocal lens 1.
- the lens blank 20 is rotated about its optical axis and the rotary tool of the lathe 21 operates during the rotation of the lens blank 20, the overlay structure 5 in the lens blank 20 a.
- the lens 1 can optionally be polished.
- the lens blank 20 could also merely be a processable starting material for a 3D printer, and the incorporation of the overlay structure 5 in the lens blank 5 is then effected by 3D printing of the starting material 20 to the multifocal lens 1.
- Fig. 9 shows a second variant of the manufacturing method, in which the overlay structure 5 calculated in the arithmetic unit is first worked into a mold blank 22 as a negative, e.g. again by means of a lathe 21 or a 3D printer. Subsequently, a lens material 20 is brought into contact with the mold blank 22 so as to produce the multifocal lens 1.
- the lens material 20 may be e.g. may already be prefabricated into a lens blank in which the overlay structure 5 is pressed in or stamped in as a stamp by means of the mold blank 22.
- the lens material 20 may be in a liquid or viscous state and cast onto the mold blank, for example in a mold
- the lens material 20 is cured, for example by means of light or heat.
- Fig. 10 shows a comparison of the intensity profile 23 of the lens 1 presented here with the intensity profile 24 of a lens according to the prior art (abscissa: distance D) from the lens [mm]; Ordinate: relative intensity I [1]).
- the prior art comparative lens is provided with a structure in which two diffractive structures having asymmetrical intensity distributions (eg, saw toothed structures) are superimposed, the first order focal point of the first diffractive structure having the second order focal point of the second diffractive structure coincides.
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- Heart & Thoracic Surgery (AREA)
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- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
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Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2018113217A RU2692165C1 (ru) | 2015-10-02 | 2016-09-29 | Мультифокальная линза и способ ее изготовления |
CA3000570A CA3000570C (en) | 2015-10-02 | 2016-09-29 | Multifocal lens and method for producing same |
JP2018536337A JP2018531434A (ja) | 2015-10-02 | 2016-09-29 | 多焦点レンズおよびその製造方法 |
US15/765,385 US10524899B2 (en) | 2015-10-02 | 2016-09-29 | Multifocal lens and method for producing same |
PL426072A PL426072A1 (pl) | 2015-10-02 | 2016-09-29 | Soczewka wieloogniskowa i sposób jej wytwarzania |
CN201680055351.XA CN108135691B (zh) | 2015-10-02 | 2016-09-29 | 多焦点镜片和用于制造多焦点镜片的方法 |
AU2016329355A AU2016329355B2 (en) | 2015-10-02 | 2016-09-29 | Multifocal lens and method for producing same |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15188049.9 | 2015-10-02 | ||
EP15188049.9A EP3150170B1 (de) | 2015-10-02 | 2015-10-02 | Multifokale linse und verfahren zu deren herstellung |
Publications (1)
Publication Number | Publication Date |
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WO2017055503A1 true WO2017055503A1 (de) | 2017-04-06 |
Family
ID=54266393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/EP2016/073349 WO2017055503A1 (de) | 2015-10-02 | 2016-09-29 | Multifokale linse und verfahren zu deren herstellung |
Country Status (11)
Country | Link |
---|---|
US (1) | US10524899B2 (de) |
EP (1) | EP3150170B1 (de) |
JP (2) | JP2018531434A (de) |
CN (1) | CN108135691B (de) |
AU (1) | AU2016329355B2 (de) |
CA (1) | CA3000570C (de) |
ES (1) | ES2660306T3 (de) |
HU (1) | HUE038672T2 (de) |
PL (1) | PL426072A1 (de) |
RU (1) | RU2692165C1 (de) |
WO (1) | WO2017055503A1 (de) |
Cited By (1)
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EP3435143A1 (de) | 2017-07-26 | 2019-01-30 | VSY Biyoteknoloji Ve Ilac Sanayi Anonim Sirketi | Multifokale ophthalmische diffraktionslinse |
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US9335563B2 (en) | 2012-08-31 | 2016-05-10 | Amo Groningen B.V. | Multi-ring lens, systems and methods for extended depth of focus |
CA3056707A1 (en) | 2017-03-17 | 2018-09-20 | Amo Groningen B.V. | Diffractive intraocular lenses for extended range of vision |
US11523897B2 (en) | 2017-06-23 | 2022-12-13 | Amo Groningen B.V. | Intraocular lenses for presbyopia treatment |
CA3067116A1 (en) | 2017-06-28 | 2019-01-03 | Amo Groningen B.V. | Diffractive lenses and related intraocular lenses for presbyopia treatment |
AU2018292030B2 (en) | 2017-06-28 | 2024-02-08 | Amo Groningen B.V. | Extended range and related intraocular lenses for presbyopia treatment |
US11327210B2 (en) | 2017-06-30 | 2022-05-10 | Amo Groningen B.V. | Non-repeating echelettes and related intraocular lenses for presbyopia treatment |
EP4258026A3 (de) | 2018-09-13 | 2023-11-15 | Hanita Lenses R.C.A. | Multifokale intraokularlinse |
WO2021136617A1 (en) | 2019-12-30 | 2021-07-08 | Amo Groningen B.V. | Lenses having diffractive profiles with irregular width for vision treatment |
AU2021283398A1 (en) | 2020-06-01 | 2023-01-05 | Icares Medicus, Inc. | Double-sided aspheric diffractive multifocal lens, manufacture, and uses thereof |
CA3217795A1 (en) | 2021-06-14 | 2022-12-22 | Alcon Inc. | Multifocal diffractive silicone hydrogel contact lenses |
CN116509598A (zh) * | 2021-11-18 | 2023-08-01 | 郑州耐视医药科技有限公司 | 一种防磨多焦点人工晶状体 |
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2015
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- 2015-10-02 EP EP15188049.9A patent/EP3150170B1/de active Active
- 2015-10-02 ES ES15188049.9T patent/ES2660306T3/es active Active
-
2016
- 2016-09-29 WO PCT/EP2016/073349 patent/WO2017055503A1/de active Application Filing
- 2016-09-29 CA CA3000570A patent/CA3000570C/en not_active Expired - Fee Related
- 2016-09-29 JP JP2018536337A patent/JP2018531434A/ja active Pending
- 2016-09-29 CN CN201680055351.XA patent/CN108135691B/zh active Active
- 2016-09-29 PL PL426072A patent/PL426072A1/pl unknown
- 2016-09-29 US US15/765,385 patent/US10524899B2/en active Active
- 2016-09-29 RU RU2018113217A patent/RU2692165C1/ru active
- 2016-09-29 AU AU2016329355A patent/AU2016329355B2/en not_active Ceased
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2020
- 2020-03-30 JP JP2020059847A patent/JP2020112820A/ja active Pending
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EP3435143A1 (de) | 2017-07-26 | 2019-01-30 | VSY Biyoteknoloji Ve Ilac Sanayi Anonim Sirketi | Multifokale ophthalmische diffraktionslinse |
WO2019020435A1 (en) | 2017-07-26 | 2019-01-31 | Vsy Biyoteknoloji Ve Ilaç San. A.S. | MULTIFOCAL OPHTHALMIC DIFFRACTIVE LENS |
US11556018B2 (en) | 2017-07-26 | 2023-01-17 | Vsy Biyoteknoloji Ve Ilaç San. A.S. | Ophthalmic multifocal diffractive lens |
Also Published As
Publication number | Publication date |
---|---|
US10524899B2 (en) | 2020-01-07 |
CA3000570A1 (en) | 2017-04-06 |
CA3000570C (en) | 2020-08-25 |
PL426072A1 (pl) | 2019-02-25 |
US20180303601A1 (en) | 2018-10-25 |
CN108135691A (zh) | 2018-06-08 |
AU2016329355B2 (en) | 2019-07-11 |
ES2660306T3 (es) | 2018-03-21 |
RU2692165C1 (ru) | 2019-06-21 |
JP2018531434A (ja) | 2018-10-25 |
AU2016329355A1 (en) | 2018-03-15 |
EP3150170B1 (de) | 2017-12-06 |
JP2020112820A (ja) | 2020-07-27 |
CN108135691B (zh) | 2020-01-17 |
HUE038672T2 (hu) | 2018-11-28 |
EP3150170A1 (de) | 2017-04-05 |
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