WO2017043261A1 - 脈波検出装置 - Google Patents

脈波検出装置 Download PDF

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Publication number
WO2017043261A1
WO2017043261A1 PCT/JP2016/073852 JP2016073852W WO2017043261A1 WO 2017043261 A1 WO2017043261 A1 WO 2017043261A1 JP 2016073852 W JP2016073852 W JP 2016073852W WO 2017043261 A1 WO2017043261 A1 WO 2017043261A1
Authority
WO
WIPO (PCT)
Prior art keywords
wrist
pulse wave
pressure
housing
pressing surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2016/073852
Other languages
English (en)
French (fr)
Japanese (ja)
Inventor
ブライアン ブリガム
正幸 福塚
新吾 山下
北川　毅
小椋　敏彦
祐之 若宮
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Omron Healthcare Co Ltd
Original Assignee
Omron Healthcare Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omron Healthcare Co Ltd filed Critical Omron Healthcare Co Ltd
Priority to EP16844124.4A priority Critical patent/EP3332701B1/en
Priority to CN201680051626.2A priority patent/CN108024735B/zh
Publication of WO2017043261A1 publication Critical patent/WO2017043261A1/ja
Priority to US15/914,825 priority patent/US11553847B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6824—Arm or wrist
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843—Monitoring or controlling sensor contact pressure

Definitions

  • the present invention relates to a pulse wave detection device.
  • a wrist-worn type that can measure biological information such as pulse and blood pressure using information detected by the pressure detection element in a state where the pressure detection element is pressed against a living body part through which an artery such as the radial artery of the wrist passes.
  • Biological information measuring devices are known (see, for example, Patent Documents 1 and 2).
  • the biological information measuring device described in Patent Document 2 is configured such that a pressure detection element protrudes toward the wrist by an appropriate amount by a restriction wall provided around the pressure detection element. For this reason, the wrist is also pressed by the restriction wall. If the pressure applied to the wrist by the restriction wall is greater than the pressure applied to the wrist by the pressure detecting element, the pressure pulse wave cannot be detected with high accuracy.
  • Patent Documents 1 and 2 do not take into account such a problem that the pressure pulse wave detection accuracy decreases.
  • the present invention has been made in view of the above circumstances, and an object thereof is to provide a pulse wave detection device capable of improving the detection accuracy of a pressure pulse wave.
  • the pulse wave detection device of the present invention includes a pressure pulse wave detection unit that detects a pressure pulse wave from the radial artery by pressing the pressure surface on which the pressure detection element is formed against the radial artery under the skin of the wrist of the subject.
  • a housing that exposes the pressure surface to the wrist and accommodates the pressure pulse wave detection unit, and the housing is subjected to pressure applied to the radial artery by the housing in a mounted state on the wrist.
  • the pressure applied to the radial artery by the pressing surface in the mounted state is configured to be smaller than the pressing pressure.
  • FIG. 2 is a perspective view of the housing 20 shown in FIG. 1 as viewed from the inner peripheral surface side in contact with the wrist H. It is a side view of the housing
  • 6 is a perspective view of a housing 20A that is a modification of the housing 20 of the biological information measuring device 100.
  • FIG. It is the perspective view which looked at the housing
  • case 20A It is a side view of case 20A. It is the top view which looked at a part of case 20A from the inner peripheral surface side which contacts a wrist.
  • FIG. 1 is a schematic diagram showing an external configuration of a biological information measuring apparatus 100 for explaining an embodiment of the present invention.
  • 2 is a perspective view of the housing 20 shown in FIG. 1 as viewed from the inner peripheral surface side in contact with the wrist H.
  • FIG. 3 is a side view of the housing 20 shown in FIG. 1 as seen from the arm side of the person to be measured.
  • the biological information measuring device 100 is used by being worn on the wrist of a person to be measured.
  • FIG. 1 shows the left wrist H of the person to be measured, and the front side in the figure is the direction in which the hand of the person to be measured exists. Further, the upper side in the figure is the direction in which the palm is facing.
  • a radius T, an ulna S, and a radial artery TD are illustrated.
  • the biological information measuring apparatus 100 includes a pressure pulse wave detection unit 10 that detects a pressure pulse wave from the radial artery TD along the rib T of the wrist H of the measurement subject, and the pressure pulse detected by the pressure pulse wave detection unit 10 Biological information such as blood pressure value and pulse rate is measured based on the wave.
  • the pressure pulse wave detection unit 10 can employ a known configuration.
  • the pressure pulse wave detection unit 10 includes a pressure detection element and a mechanism for pressing the pressure detection element against the skin, and detects the pressure pulse wave by the pressure detection element.
  • the biological information measuring apparatus 100 includes a pressure pulse wave detection unit 10 and a biological information calculation unit (not shown) that calculates biological information such as a blood pressure value and a pulse rate based on the pressure pulse wave detected by the pressure pulse wave detection unit 10.
  • casing 20 which accommodates is provided.
  • the biological information measuring device 100 only needs to have at least the pressure pulse wave detection unit 10 and functions as a pulse wave detection device.
  • the biological information calculation unit may be provided in a device different from the biological information measuring device 100.
  • the pressure pulse wave detector 10 has a pressing surface 10a on which one or a plurality of pressure detecting elements are formed (see FIGS. 2 and 3), and the pressing surface 10a is perpendicular to the pressing surface 10a by a pressing mechanism (not shown). It can move in the direction. As shown in FIG. 2, the pressure pulse wave detection unit 10 is housed in the housing 20 with the pressing surface 10 a exposed to the wrist side in the mounted state.
  • the housing 20 is configured to be wound along a circumferential direction of the wrist H (hereinafter also referred to as a circumferential direction), and is a substantially U-shaped housing in which the ulna S side of the wrist H is opened.
  • the housing 20 is configured such that the ulna S is not covered between both ends in the circumferential direction of the wrist H.
  • the housing 20 includes a rigid portion 1 including a rigid portion 1a and a rigid portion 1b, and a soft portion 2 having a lower rigidity than the rigid portion 1.
  • the rigid portion 1a constitutes the tip portion of the housing 20, and the thickness is substantially constant from the tip of the housing 20 to a predetermined distance, and from the inner peripheral surface side of the housing 20 toward the outer peripheral surface side after the predetermined distance.
  • the thickness is thin.
  • a part of the flexible part 2 is superimposed on the part where the thickness of the rigid part 1a is reduced.
  • the soft part 2 has a shape extending from the overlapping part with the rigid part 1 a to the rear end of the housing 20.
  • the flexible portion 2 has a thickness that decreases from the outer peripheral surface side to the inner peripheral surface side of the housing 20 at the overlapping portion with the rigid portion 1a, and the portion of the housing 20 that is wound around the back side of the hand of the housing 20. The thickness decreases from the inner peripheral surface side toward the outer peripheral surface side.
  • a rigid portion 1b is superimposed on a portion where the thickness of the soft portion 2 on the back side of the hand is reduced.
  • Each of the rigid portion 1a and the rigid portion 1b and the flexible portion 2 are connected by adhesion such as adhesion or welding, or are connected by a connection pin.
  • the rigid part 1a accommodates the pressure pulse wave detection part 10.
  • the rigid portion 1a stabilizes the position of the pressure pulse wave detection unit 10 with respect to the radial artery TD when the housing 20 is attached to the wrist H, and protects the pressure pulse wave detection unit 10 including a precision element.
  • the first material having high rigidity is used.
  • the first material for example, resin or metal is used.
  • Part of the pressure pulse wave detection unit 10 (a portion including the pressing surface 10a) is inserted into a through hole provided in a portion of the soft portion 2 that overlaps the rigid portion 1a, and the pressing surface 10a is exposed to the wrist side. It has become.
  • the soft part 2 is composed of a second material having lower rigidity than the first material.
  • a second material having lower rigidity than the first material.
  • an elastic member or a shape memory alloy is used as the second material.
  • the rigid portion 1b is made of the same first material as that of the rigid portion 1a, but is made of a material different from the first material (however, a material having higher rigidity than the second material is preferable). May be.
  • the portion wound around from the palm side to the back of the hand is constituted by the soft part 2, so that the case 20 can be easily deformed according to the shape of the wrist H.
  • a band fastener 22 for fixing a band (not shown) for fixing the housing 20 to the wrist H is provided on the inner peripheral surface (the surface facing the wrist H) of the rigid portion 1 b. Yes.
  • the band fastener 22 is configured by a cylindrical metal fitting. The base end of the band is fixed to the band fastener 22.
  • Holes 11 and 12 for locking the band to the rigid portion 1a are provided side by side along the circumferential direction of the wrist H on the outer peripheral surface of the rigid portion 1a (the surface opposite to the surface facing the wrist H). ing.
  • the band is a band extending along the longitudinal direction of the casing 20 (synonymous with the circumferential direction of the wrist H), and is composed of a member having rigidity lower than that of the casing 20. For example, cloth or leather is used for this member.
  • This band is provided with a hook-and-loop fastener for attaching the bands together.
  • the person to be measured turns the tip of the band fixed to the band fastener 22 to the palm side, inserts it into the hole 12, and pulls out from the hole 11.
  • the measured person pulls the band taken out from the hole 11 toward the back side of the hand and adjusts the tightening condition, and then locks the bands to each other with a hook-and-loop fastener, thereby fixing the casing 20 to the wrist H by the band.
  • FIG. 4 is a plan view of a part of the housing 20 as viewed from a direction perpendicular to the pressing surface 10a of the pressure pulse wave detection unit 10 accommodated in the housing 20.
  • FIG. A portion surrounded by a thick line shown in FIG. 4 indicates a portion that can come into contact with the wrist while the housing 20 is attached to the wrist.
  • the flexible portion 2 in the portion overlapping the pressing surface 10a in the direction Y (the range indicated by reference numeral 30 in FIG. 4) can come into contact with the wrist. Further, since there are cavities 2a and 2b inside this portion, the cavities 2a and 2b allow the portion to be deformed in a direction perpendicular to the pressing surface 10a.
  • the biological information measuring apparatus 100 is used by attaching the housing 20 to the wrist so that the pressing surface 10a can press the radial artery TD of the measurement subject. That is, in the wearing state recommended by the manufacturer, the pressing surface 10a and the radial artery TD necessarily overlap each other. When the pressing surface 10a and the radial artery TD overlap each other, the soft part 2 in the range indicated by reference numeral 30 in FIG. 4 also overlaps the radial artery TD somewhere.
  • the soft part 2 and the pressing surface 10a in the range indicated by reference numeral 30 in FIG. 4 are in contact with the skin of the measurement subject, and the pressing surface 10a is further pressed toward the radial artery TD.
  • the soft part 2 Since the cavities 2a and 2b are present in the soft part 2 in this range, the soft part 2 is deformed in a state in which the cavities 2a and 2b are collapsed in the mounted state, so that the soft part 2 in this range causes the radial artery TD to be deformed.
  • the compression pressure is reduced.
  • the pressure applied to the radial artery TD by the soft part 2 can be made sufficiently smaller than the pressure applied to the radial artery TD by the pressing surface 10a.
  • the radial artery TD is almost compressed only by the pressing surface 10a, and the pressure pulse wave can be detected with high accuracy.
  • the casing 20 has cavities 2a and 2b that are longer in the circumferential direction X than the range indicated by reference numeral 30 in FIG. 4, but at least if there are cavities in this range, the radial artery TD caused by the flexible portion 2 is present.
  • the effect of reducing the compression pressure to the can be obtained.
  • FIGS. 1 to 4 by forming the cavities 2a and 2b in a range wider than this range, the flexible portion 2 in this range can be more easily deformed, which is effective.
  • the rigidity of the soft part 2 is not particularly limited.
  • the soft part 2 may be made of the same material as the rigid part 1a.
  • the cavities 2a and 2b may be filled with a material having lower rigidity than the soft part 2.
  • the flexible portion 2 in the range indicated by reference numeral 30 in FIG. 4 can be deformed in a direction perpendicular to the pressing surface 10a. For this reason, the compression pressure to the radial artery TD by the housing
  • FIG. 5 is a perspective view of a housing 20 ⁇ / b> A that is a modification of the housing 20 of the biological information measuring apparatus 100.
  • FIG. 6 is a perspective view of the housing 20A as seen from the inner peripheral surface side that comes into contact with the wrist.
  • FIG. 7 is a side view of the housing 20A as viewed from the arm side of the measurement subject.
  • the housing 20A has a configuration in which the portions of the housing 20 having the cavities 2a and 2b of the soft portion 2 are changed to the recesses 2c and 2d.
  • FIG. 8 is a plan view of a part of the housing 20A as seen from a direction perpendicular to the pressing surface 10a of the pressure pulse wave detector 10 accommodated in the housing 20A. A portion surrounded by a thick line shown in FIG. 8 indicates a portion that can contact the wrist when the housing 20A is attached to the wrist.
  • recesses 2 c and 2 d are formed on the inner peripheral surface of the portion adjacent to the pressure pulse wave detection unit 10 in both ends of the soft part 2 in the direction Y orthogonal to the circumferential direction X of the wrist in the wearing state. Is formed.
  • the housing 20A has a portion where the portion overlapping the pressing surface 10a in the direction Y (the range indicated by reference numeral 30 in FIG. 8) cannot contact the wrist in the mounted state (in the direction perpendicular to the pressing surface 10a).
  • the position is closer to the outer peripheral surface of the housing 20A than to the pressing surface 10a.
  • the radial artery TD of the measurement subject is compressed only by the pressing surface 10a. Therefore, the pressure applied to the radial artery TD by the housing 20A can be made sufficiently smaller than the pressure applied to the radial artery TD by the pressing surface 10a, and the pressure pulse wave can be accurately detected.
  • the housing 20A has the recesses 2c and 2d larger in the circumferential direction X than the range indicated by reference numeral 30 in FIG. 8, but at least if there is a recess in this range, the radial artery TD by the housing 20A The effect of reducing the compression pressure to the can be obtained.
  • the disclosed pulse wave detection device includes a pressure pulse wave detection unit that detects a pressure pulse wave from the radial artery by pressing the pressure surface on which the pressure detection element is formed against the radial artery under the skin of the subject's wrist.
  • a housing that accommodates the pressure pulse wave detection unit with the pressing surface exposed to the wrist side, and the housing is compressed against the radial artery by the housing in a mounted state on the wrist.
  • the pressure is configured to be smaller than the pressure applied to the radial artery by the pressing surface in the wearing state.
  • the portion of the housing that overlaps the pressing surface in a direction orthogonal to the circumferential direction of the wrist in the mounted state is on the wrist in the mounted state. It is in a position where contact is impossible.
  • the portion of the housing that overlaps the pressing surface in a direction orthogonal to the circumferential direction of the wrist in the mounted state is on the wrist in the mounted state. It is in a position where contact is impossible.
  • the portion that can come into contact with the wrist has a cavity inside, and the cavity can be deformed by the cavity in a direction perpendicular to the pressing surface.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physiology (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
PCT/JP2016/073852 2015-09-07 2016-08-15 脈波検出装置 Ceased WO2017043261A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP16844124.4A EP3332701B1 (en) 2015-09-07 2016-08-15 Pulse wave detector
CN201680051626.2A CN108024735B (zh) 2015-09-07 2016-08-15 脉搏波检测装置
US15/914,825 US11553847B2 (en) 2015-09-07 2018-03-07 Pulse wave detecting device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015-175964 2015-09-07
JP2015175964A JP6540396B2 (ja) 2015-09-07 2015-09-07 脈波検出装置

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US15/914,825 Continuation US11553847B2 (en) 2015-09-07 2018-03-07 Pulse wave detecting device

Publications (1)

Publication Number Publication Date
WO2017043261A1 true WO2017043261A1 (ja) 2017-03-16

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PCT/JP2016/073852 Ceased WO2017043261A1 (ja) 2015-09-07 2016-08-15 脈波検出装置

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US (1) US11553847B2 (enExample)
EP (1) EP3332701B1 (enExample)
JP (1) JP6540396B2 (enExample)
CN (1) CN108024735B (enExample)
WO (1) WO2017043261A1 (enExample)

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Publication number Priority date Publication date Assignee Title
JP1615126S (enExample) * 2017-12-27 2018-10-09

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01122704U (enExample) * 1988-02-17 1989-08-21
JPH03114207U (enExample) * 1990-01-10 1991-11-22
JPH05329117A (ja) * 1992-05-28 1993-12-14 Sanyo Electric Co Ltd バンド型情報検知具
WO1998042254A1 (en) * 1997-03-25 1998-10-01 Seiko Epson Corporation Pulse wave detector, pulsation detector and pressure detector
JP2002224064A (ja) * 2001-02-02 2002-08-13 Omron Corp 圧脈波センサ

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3342129B2 (ja) * 1993-10-26 2002-11-05 日本コーリン株式会社 圧脈波センサ
US6120460A (en) * 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
JP3631979B2 (ja) * 2001-06-06 2005-03-23 コーリンメディカルテクノロジー株式会社 心機能評価機能付き血圧測定装置
US6730038B2 (en) * 2002-02-05 2004-05-04 Tensys Medical, Inc. Method and apparatus for non-invasively measuring hemodynamic parameters using parametrics
CN1524490A (zh) * 2003-02-25 2004-09-01 北京泰达新兴医学工程技术有限公司 压力型脉搏波检测装置及使用该装置的血压计
US20060111636A1 (en) * 2004-11-23 2006-05-25 Jacober Jeffrey M Wrist-mount blood pressure monitor
JP2008168054A (ja) * 2007-01-15 2008-07-24 Citizen Holdings Co Ltd 手首装着型の生体測定装置用のバンド
JP5076996B2 (ja) * 2008-03-19 2012-11-21 オムロンヘルスケア株式会社 血圧情報測定装置
JP5329117B2 (ja) * 2008-04-07 2013-10-30 株式会社プレックス 布類展張搬送方法及び布類展張搬送機
US20120221041A1 (en) * 2011-02-25 2012-08-30 St. Jude Medical Systems Ab Artery compressor
JP5821657B2 (ja) * 2012-01-25 2015-11-24 オムロンヘルスケア株式会社 測定装置および測定方法
US8948832B2 (en) * 2012-06-22 2015-02-03 Fitbit, Inc. Wearable heart rate monitor
US9427239B2 (en) * 2013-07-12 2016-08-30 Semier Technologies, Inc. Apparatus and method of use for an adjustable radial and ulnar compression wristband
US20150265214A1 (en) * 2014-03-24 2015-09-24 Samsung Electronics Co., Ltd. Adjustable sensor support structure for optimizing skin contact
US9904320B2 (en) * 2014-05-30 2018-02-27 Microsoft Technology Licensing, Llc Battery compartments for wearable electronic device
US9724003B2 (en) * 2014-11-14 2017-08-08 Intel Corporation Ultra-low power continuous heart rate sensing in wearable devices

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01122704U (enExample) * 1988-02-17 1989-08-21
JPH03114207U (enExample) * 1990-01-10 1991-11-22
JPH05329117A (ja) * 1992-05-28 1993-12-14 Sanyo Electric Co Ltd バンド型情報検知具
WO1998042254A1 (en) * 1997-03-25 1998-10-01 Seiko Epson Corporation Pulse wave detector, pulsation detector and pressure detector
JP2002224064A (ja) * 2001-02-02 2002-08-13 Omron Corp 圧脈波センサ

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP3332701A4 *

Also Published As

Publication number Publication date
EP3332701B1 (en) 2022-10-19
JP2017051274A (ja) 2017-03-16
EP3332701A1 (en) 2018-06-13
CN108024735B (zh) 2021-07-13
US11553847B2 (en) 2023-01-17
EP3332701A4 (en) 2019-03-27
CN108024735A (zh) 2018-05-11
US20180192892A1 (en) 2018-07-12
JP6540396B2 (ja) 2019-07-10

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