WO2016183908A1 - 用于o2o线下调理的治疗行经腹泻的中药组合物及其制备方法 - Google Patents

用于o2o线下调理的治疗行经腹泻的中药组合物及其制备方法 Download PDF

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WO2016183908A1
WO2016183908A1 PCT/CN2015/083116 CN2015083116W WO2016183908A1 WO 2016183908 A1 WO2016183908 A1 WO 2016183908A1 CN 2015083116 W CN2015083116 W CN 2015083116W WO 2016183908 A1 WO2016183908 A1 WO 2016183908A1
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chinese medicine
traditional chinese
medicine composition
servings
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French (fr)
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张贯京
陈兴明
葛新科
张少鹏
方静芳
普拉纽克⋅克里斯基捏
古列莎⋅艾琳娜
波达别特⋅伊万
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Shenzhen Qianhai AnyCheck Information Technology Co Ltd
E Techno Information Technologies Co Ltd
Bio Tech Academy China Co Ltd
Shenzhen Gongchuang Science and Technology Development Co Ltd
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E Techno Information Technologies Co Ltd
Bio Tech Academy China Co Ltd
Shenzhen Gongchuang Science and Technology Development Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487—Psoralea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/746—Morinda
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/754—Evodia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)

Definitions

  • the invention relates to the field of life health technology, in particular to a traditional Chinese medicine composition for treating diarrhea for O2O line conditioning and a preparation method thereof.
  • the object of the present invention is to provide a traditional Chinese medicine composition for treating diarrhea for O2O line conditioning and a preparation method thereof, which have the effects of replenishing qi and strengthening spleen, warming kidney and dispelling cold, relieving diarrhea and nourishing blood and soothe the nerves.
  • the spleen is weak, the kidney is weak, and the diarrhea caused by it has a good therapeutic effect, and it is safe, non-toxic and has no side effects, thereby achieving the effect of treating both the symptoms and the root causes.
  • the present invention provides a traditional Chinese medicine composition for treating diarrhea for O2O line conditioning, which comprises the following parts by weight:
  • 1 ⁇ 5 servings of Codonopsis pilosula 1 ⁇ 3 servings of Atractylodes, 1 ⁇ 2 servings, 2 ⁇ 5 servings of Huanren, 1 ⁇ 4 parts of Wujing, 1 ⁇ 3 parts of nutmeg, 1 ⁇ 3 parts of psoralen, Bayu Tian 1 ⁇ 2 parts, 1 ⁇ 2 parts of Schisandra, 1 ⁇ 3 parts of red dates, 1 ⁇ 3 parts of longan, 1 ⁇ 3 parts of lotus seeds, 1 ⁇ 2 parts of platycodon grandiflorum.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • 3 ⁇ 5 servings of Codonopsis pilosula 2 ⁇ 3 servings of Atractylodes, 1 ⁇ 2 servings, 3 ⁇ 5 servings of Huanren, 2 ⁇ 4 parts of Wujing, 2 ⁇ 3 parts of nutmeg, 2 ⁇ 3 parts of psoralen, Bayu Tian 1 ⁇ 2 parts, 1 ⁇ 2 parts of Schisandra, 1 ⁇ 3 parts of red dates, 2 ⁇ 3 parts of longan, 1.5 ⁇ 3 parts of lotus seeds, 1.5 ⁇ 2 parts of platycodon grandiflorum.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • 3 ⁇ 4 servings of Codonopsis pilosula 2.5 ⁇ 3 servings of Atractylodes, 1.5 ⁇ 2 servings, 4 ⁇ 5 servings of Huanren, 2 ⁇ 3 parts of Wujing, 2 ⁇ 2.5 parts of nutmeg, 2.5 ⁇ 3 parts of psoralen, 1.5 days of Basil Day 2 parts, 1 ⁇ 1.8 parts of Schisandra, 2 ⁇ 3 parts of red dates, 2.5 ⁇ 3 parts of longan, 1.5 ⁇ 2.5 parts of lotus seeds, 1.5 ⁇ 1.8 parts of platycodon grandiflorum.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Codonopsis 3 parts of Codonopsis, 2.5 parts of Atractylodes, 1.5 parts of medlar, 4 parts of Coix seed, 2 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 1.5 parts of Morinda, 1 part of Schisandra, 2 parts of red dates, 2.5 parts of longan, lotus seeds 1.5 parts, 1.5 parts of Campanulaceae.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Codonopsis 3 parts of Codonopsis, 3 parts of Atractylodes, 2 parts of medlar, 4 parts of Coix seed, 2 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 1.5 parts of Morinda, 1 part of Schisandra, 2 parts of red dates, 2.5 parts of longan, 2.5 pieces of lotus seeds 1.5 parts, 1.6 platycodon grandiflorum.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Codonopsis 2.5 parts of Atractylodes, 1.5 parts of alfalfa, 5 parts of coix seed, 2.5 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 1.5 parts of Morinda, 1 part of Schisandra, 2 parts of red dates, 2.5 parts of longan, lotus seeds 1.5 parts, 1.7 servings of Campanulaceae.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Codonopsis 3 parts of Atractylodes, 1.5 parts of medlar, 4 parts of Coix seed, 2 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 1.5 parts of Morinda, 1 part of Schisandra, 2 parts of red dates, 2.5 parts of longan, lotus seeds 2.5 parts, 1.6 parts of Campanulaceae.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Codonopsis 4 parts of Codonopsis, 3 parts of Atractylodes, 2 parts of medlar, 4 parts of Coix seed, 2 parts of Evodia, 2.5 parts of nutmeg, 2.5 parts of psoralen, 2 parts of Morinda, 1.5 parts of Schisandra, 3 parts of red dates, 3 parts of longan, lotus seeds 2.1 parts, 1.6 parts of Campanulaceae.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Codonopsis 4 parts of Codonopsis, 3 parts of Atractylodes, 2 parts of medlar, 4 parts of Coix seed, 3 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 2 parts of Morinda, 1.5 parts of Schisandra, 3 parts of red dates, 2.5 parts of longan, lotus seeds 2 servings, 1.6 platycodon grandiflorum.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • the present invention also provides a method for preparing a traditional Chinese medicine composition for treating diarrhea for O2O line conditioning, the preparation method comprising the following steps:
  • Codonopsis pilosula, Atractylodes, Poria, Coix Seed, Wujing, Nutmeg, Buguzhi, Bayu Tian, Schisandra, Red Date, and Longan are soaked in 8-12 times of water for 40 minutes, then boiled. -60 minutes, pour out the decoction AA;
  • the invention has the components of the medicine, such as Codonopsis pilosula, Atractylodes, Poria, Coix Seed, Wujing, Nutmeg, Buguzhi, Bayu Tian, Schisandra, Jujube, and Longan, and synergistic action thereof to play the role of qi and spleen, Wenshen San
  • Codonopsis pilosula Atractylodes
  • Poria Coix Seed
  • Wujing Nutmeg, Buguzhi, Bayu Tian
  • Schisandra Schisandra
  • Jujube Jujube
  • Longan and synergistic action thereof to play the role of qi and spleen
  • Wenshen San The effects of cold, sputum diarrhea and nourishing blood and soothe the nerves have a good therapeutic effect on diarrhea caused by weak temper and weak kidney, and it is safe, non-toxic and has no side effects, thus achieving the effect of treating both the symptoms and the root causes.
  • the invention provides a traditional Chinese medicine composition for treating diarrhea for O2O offline conditioning, the Chinese medicine composition consisting of the following parts by weight:
  • 1 ⁇ 5 servings of Codonopsis pilosula 1 ⁇ 3 servings of Atractylodes, 1 ⁇ 2 servings, 2 ⁇ 5 servings of Huanren, 1 ⁇ 4 parts of Wujing, 1 ⁇ 3 parts of nutmeg, 1 ⁇ 3 parts of psoralen, Bayu Tian 1 ⁇ 2 parts, 1 ⁇ 2 parts of Schisandra, 1 ⁇ 3 parts of red dates, 1 ⁇ 3 parts of longan, 1 ⁇ 3 parts of lotus seeds, 1 ⁇ 2 parts of platycodon grandiflorum.
  • Codonopsis has the effect of supplementing the vital energy, nourishing the blood and nourishing the blood; it is used for spleen and stomach weakness, qi and blood loss, long-term diarrhea, body weakness and less thirst.
  • Atractylodes It has the effect of replenishing spleen and tonifying the stomach, dampness and spleen; it is used for weak spleen and stomach, not thinking about diet, fatigue, qi, qi, diarrhea and dizziness.
  • ⁇ It can not only strengthen the spleen, but also spleen, and it can calm the phlegm and not harm the righteousness; it has the effect of moisturizing and spleen; it is used for diarrhea caused by spleen deficiency and lower embolism. It is often used in combination with Codonopsis, Atractylodes, and Chinese yam. It has the effect of taking both specimens into consideration, and is an adjuvant for lung and spleen and qi deficiency.
  • Coix seed It has the effects of dampness and spleen, spleen and remove phlegm and clearing heat and draining pus. It is used for diarrhea and other diseases.
  • Wu Hao It has the effect of relieving pain in the middle and relieving vomiting and stomach; it is used for dirty cold vomiting and diarrhea, abdominal pain, abdominal pain and five diarrhea.
  • Nutmeg It has the effect of warming the air and dissolving the intestines; it is used for abdominal pain, diarrhea, cold phlegm, vomiting and food.
  • Buguzhi It has the effect of tonifying kidney and helping yang; it is used for kidney deficiency cold diarrhea and cold knee pain.
  • the fruit of psoralen contains about 20% of volatile oil, mainly composed of organic acid, methyl glycoside, alkali-soluble resin, non-volatile anthraquinone oil and saponin. Modern research has shown that psoralen can shorten the bleeding time and reduce the amount of bleeding; at the same time, it has obvious contraction effect on the uterus.
  • Bayu Tian Weixin, Gan, sexually lukewarm, with the effect of tonifying kidney, strengthening bones and rheumatism; used for less abdominal pain, cold infertility, irregular menstruation and kidney deficiency.
  • “Ba Yu Tian”, also known as “chicken and intestine” is a grass vine plant, which is one of the “four major southern medicines”. It can replenish kidney yang, strengthen bones and muscles, remove rheumatism, improve immune function, lower blood pressure and cortex.
  • the role of hormones, Heng has the name of "Southern ginseng”.
  • Bayu Tian and galangal, cinnamon, Wujing and other drugs in combination can play the role of warming kidney and regulating menstruation. Modern research has shown that Morinda has anti-fatigue and immune-enhancing capabilities.
  • Schisandra tastes sour, sweet, warm, return to the lungs, heart and kidney, menstruation; has astringent solid, congestive lung and kidney and Shengjin sweating effect; used for long-term diarrhea, lung deficiency, asthma, cough, dry mouth for thirst, Spontaneous sweating and labor injuries are thin and embolism.
  • Schisandra chinensis contains a variety of nutrients: such as schisandra, malic acid, citric acid, tartaric acid, succinic acid, fatty oil, volatile oil, sugar, resin, vitamin C, etc., also contains tungsten, iron, manganese, Trace elements such as zinc and phosphorus.
  • Schisandra contains schisandrin.
  • Schisandrin In addition to regulating gastric secretion and exciting the uterus, Schisandrin also has the effect of inhibiting the proliferation of pathogenic microorganisms such as bacteria. As a kind of food, Schisandra chinensis leaves have therapeutic effect. Long-term consumption can play the role of warming and replenishing vital energy, and it is beneficial to the conditioning of various imbalances in the body. Especially for people who are chronically ill and physically weak, when it is not appropriate to abuse drugs for replenishment, they may wish to use their food to make food supplements.
  • Jujube sweet, warm, with Buzhong Yiqi, nourishing blood and calming the nerves and alleviating the medicinal properties; used for spleen deficiency, eating less stool and qi and blood deficiency.
  • Regular consumption jujube can treat diseases such as weakness, neurasthenia, spleen and stomach disharmony, indigestion and anemia, and there are "three eclipses of eclipse, no one is old at the age of 100".
  • Modern pharmacology shows that jujube contains protein, fat, sugar, organic acids, vitamin A, vitamin C. Rich in nutrients such as trace amounts of calcium and amino acids.
  • Jujube is rich in calcium and iron, which plays an important role in the prevention and treatment of osteoporosis and postpartum anemia.
  • Jujube Middle-aged and elderly people often have osteoporosis during menopause. Adolescents and women who are at the peak of growth and development are prone to anemia. Jujube is very common in patients with anemia. The ideal therapeutic effect is usually unmatched by drugs. Jujube is shared with Codonopsis pilosula and Atractylodes sinensis. It can supplement the qi and spleen and stomach, and increase the appetite and diarrhea.
  • Longan It has the functions of replenishing the heart and spleen, replenishing qi and blood, strengthening the spleen and stomach and nourishing the muscles; it is used for thinking about spleen, dizziness, insomnia, palpitations, post-mortem deficiency or postpartum physical weakness, and blood loss due to spleen deficiency. . Modern medical practice proves that longan has the effect of beauty and longevity.
  • Lotus seeds It has the effects of replenishing spleen and stopping diarrhea, stopping the band, replenishing kidney and phlegm, and nourishing the heart and soothe the nerves; it is used for spleen deficiency, diarrhea, nocturnal emission and palpitations and insomnia.
  • Platycodon grandiflorum The platycodon is clear, and the lungs are good for gas.
  • Codonopsis can effectively improve spleen and stomach weakness, qi and blood loss, long-term diarrhea, body weakness and less thirst, and help to replenish qi and nourish the blood;
  • Atractylodes can help spleen and stomach, Dampness and medium, can effectively improve the spleen and stomach, do not think about diet, burnout, qi, swell, diarrhea and dizziness, spontaneous sputum;
  • sputum helps spleen and spleen, can effectively improve diarrhea caused by spleen deficiency, Take the next embolism;
  • Coix seed helps the dampness and spleen, Shujin removes phlegm and clears away heat and discharges pus, which can effectively improve the diarrhea and other embolism;
  • Wusong helps to relieve pain and relieve vomiting and stomach, can effectively improve the dirty Cold vomiting and diarrhea, abdominal pain, abdominal pain and five diarrhea; nutmeg helps to warm the stomach and eliminate the effect of the intestines, can effectively improve
  • Schisandra contains Schisandrin, Schisandrin In addition to regulating the secretion of gastric juice and exciting the uterus, it also has the effect of inhibiting the proliferation of pathogenic microorganisms such as bacteria; red dates help to replenish vital energy, nourish blood and soothe the nerves and alleviate the medicinal properties, and can effectively improve spleen deficiency, eating less stools and qi and blood deficiency. Deficiency syndrome; longan helps to replenish the heart and spleen, replenish qi and blood, strengthen the spleen and stomach and raise muscles. It can effectively improve the thinking of spleen, dizziness, insomnia, palpitations, post-mortem deficiency or postpartum physical weakness and due to spleen deficiency.
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • 3 ⁇ 5 servings of Codonopsis pilosula 2 ⁇ 3 servings of Atractylodes, 1 ⁇ 2 servings, 3 ⁇ 5 servings of Huanren, 2 ⁇ 4 parts of Wujing, 2 ⁇ 3 parts of nutmeg, 2 ⁇ 3 parts of psoralen, Bayu Tian 1 ⁇ 2 parts, 1 ⁇ 2 parts of Schisandra, 1 ⁇ 3 parts of red dates, 2 ⁇ 3 parts of longan, 1.5 ⁇ 3 parts of lotus seeds, 1.5 ⁇ 2 parts of platycodon grandiflorum.
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • 3 ⁇ 4 servings of Codonopsis pilosula 2.5 ⁇ 3 servings of Atractylodes, 1.5 ⁇ 2 servings, 4 ⁇ 5 servings of Huanren, 2 ⁇ 3 parts of Wujing, 2 ⁇ 2.5 parts of nutmeg, 2.5 ⁇ 3 parts of psoralen, 1.5 days of Basil Day 2 parts, 1 ⁇ 1.8 parts of Schisandra, 2 ⁇ 3 parts of red dates, 2.5 ⁇ 3 parts of longan, 1.5 ⁇ 2.5 parts of lotus seeds, 1.5 ⁇ 1.8 parts of platycodon grandiflorum.
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • Codonopsis 3 parts of Codonopsis, 2.5 parts of Atractylodes, 1.5 parts of medlar, 4 parts of Coix seed, 2 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 1.5 parts of Morinda, 1 part of Schisandra, 2 parts of red dates, 2.5 parts of longan, lotus seeds 1.5 parts, 1.5 parts of Campanulaceae.
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • Codonopsis 3 parts of Codonopsis, 3 parts of Atractylodes, 2 parts of medlar, 4 parts of Coix seed, 2 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 1.5 parts of Morinda, 1 part of Schisandra, 2 parts of red dates, 2.5 parts of longan, 2.5 pieces of lotus seeds 1.5 parts, 1.6 platycodon grandiflorum.
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • Codonopsis 2.5 parts of Atractylodes, 1.5 parts of alfalfa, 5 parts of coix seed, 2.5 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 1.5 parts of Morinda, 1 part of Schisandra, 2 parts of red dates, 2.5 parts of longan, lotus seeds 1.5 parts, 1.7 servings of Campanulaceae.
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • Codonopsis 3 parts of Atractylodes, 1.5 parts of medlar, 4 parts of Coix seed, 2 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 1.5 parts of Morinda, 1 part of Schisandra, 2 parts of red dates, 2.5 parts of longan, lotus seeds 2.5 parts, 1.6 parts of Campanulaceae.
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • Codonopsis 4 parts of Codonopsis, 3 parts of Atractylodes, 2 parts of medlar, 4 parts of Coix seed, 2 parts of Evodia, 2.5 parts of nutmeg, 2.5 parts of psoralen, 2 parts of Morinda, 1.5 parts of Schisandra, 3 parts of red dates, 3 parts of longan, lotus seeds 2.1 parts, 1.6 parts of Campanulaceae.
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • Codonopsis 4 parts of Codonopsis, 3 parts of Atractylodes, 2 parts of medlar, 4 parts of Coix seed, 3 parts of Evodia, 2 parts of nutmeg, 2.5 parts of psoralen, 2 parts of Morinda, 1.5 parts of Schisandra, 3 parts of red dates, 2.5 parts of longan, lotus seeds 2 servings, 1.6 platycodon grandiflorum.
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • the components of the traditional Chinese medicine composition for treating diarrhea for O2O line conditioning are as follows:
  • the preparation method comprises the following steps:
  • Codonopsis pilosula, Atractylodes, Poria, Coix Seed, Wujing, Nutmeg, Buguzhi, Bayu Tian, Schisandra, Red Date, and Longan are soaked in 8-12 times of water for 40 minutes, then boiled. -60 minutes, pour out the decoction AA;
  • Symptoms It has typical clinical manifestations and is consistent with the diagnostic criteria for menstrual diarrhea such as diarrhea. No medication has been given for one week.
  • Cure The clinical symptoms disappear and there is no recurrence within 3 months.
  • the drug of the present invention was used for treatment. After treatment, after statistical treatment, 30 patients were cured, accounting for 62.5%, 11 patients were improved, accounting for 34.375%, and 1 patient was invalid. Accounted for 3.125%, the total effective rate was 96.87%.
  • Case 1 Patient Miss Liu, 16 years old, came to the clinic in September 2014. Because she usually likes to eat cold drinks, the symptoms at the time of diagnosis: menstrual diarrhea, cold limbs, and abdominal pain, diarrhea is sputum, 2 times a day, There is no strength in the whole body.
  • the prescription of the present invention was administered twice a day, morning and evening, and the abdominal pain was relieved after the third day, and the stool was gradually normal; after five days, the patient continued to take two menstrual cycles, the pain symptoms completely disappeared, and the bowel movement was normal. After six months of follow-up, no recurrence was observed.
  • Case 2 Miss Zhang, 28 years old, came to the clinic in February 2014. Symptoms at the time of diagnosis: menstrual diarrhea, mental dysfunction, lack of strength, drowsiness, and painful stomach, no appetite; diarrhea is watery Then, many times a day.
  • the prescription of the present invention was administered twice a day, morning and evening, and after 4 days, the stomach pain was relieved and the appetite returned to normal; after 3 consecutive menstrual cycles, the bowel movement was normal, the appetite was normal, and the pain disappeared. After one year of follow-up, no recurrence was observed.
  • Case 3 Patient Miss Li, 45 years old, came to the clinic in November 2013. The patient is usually weak and has a long course of disease for 2 years. Symptoms at the time of diagnosis: menstrual diarrhea, pale complexion, diarrhea is more serious, and after eating Complete discharge, dehydration, no strength, accompanied by abdominal pain.
  • the prescription of the present invention was administered twice a day, once in the morning and evening, and the diarrhea was significantly relieved after the fourth day of administration; the symptoms of diarrhea and abdominal pain completely disappeared after 4 months of continuous administration. There was no recurrence after 1 year and 4 months of follow-up.

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Abstract

用于O2O线下调理的治疗行经腹泻的中药组合物及其制备方法，该组合物使用重量份的党参1-5份、白术1-3份、茯苓1-2份、薏仁2-5份、吴茱萸1-4份、肉豆蔻1-3份、补骨脂1-3份、巴戟天1-2份、五味子1-2份、红枣1-3份、桂圆1-3份、莲子1-3份、桔梗1-2份制成。

Description

用于O2O线下调理的治疗行经腹泻的中药组合物及其制备方法
技术领域
本发明涉及生命健康技术领域，尤其涉及一种用于O2O线下调理的治疗行经腹泻的中药组合物及其制备方法。
背景技术
对于很多女性来说，在月经期间，都会有腹泻的症状出现，每日可腹泻一次至数次，根据不同人的体质而腹泻次数有所不同，而有些患者在腹泻时常常伴有小腹疼痛；腹泻可为溏便，也可为水样便，甚或进食之物完全排出；腹泻后常常伴有精神萎靡、浑身没有力气、昏昏欲睡、并且患者常常感觉肚子胀痛、没有食欲；只有等到经期结束以后，大便才恢复正常，也有些患者至月经结束数日后才停止腹泻，这些症状称为行经腹泻。对于行经腹泻的发病原因，现代医学认为与女性月经期间体内激素比例失调有关；而中医则认为行经泄泻多与素体脾虚肾弱有关，脾气虚弱，脾的运化水湿功能失常，所以出现腹泻。目前，治疗行经腹泻的方法主要采用一些止泻西药来治疗，只能暂时缓解腹泻，而不能根治，给患者带来了不必要的痛苦，影响患者正常的工作和学习。
基于此，需要寻找一种高效可靠的药物来治疗行经腹泻，为女性患者减轻痛苦，并且能够达到标本兼治的效果。
发明内容
本发明的目的在于提供一种用于O2O线下调理的治疗行经腹泻的中药组合物及其制备方法，具有益气健脾、温肾散寒、涩肠止泻和养血安神的功效，对于脾脏虚弱、肾气虚弱等造成的行经腹泻，具有良好的治疗效果，而且安全、无毒无副作用，从而达到标本兼治的效果。
为实现上述目的，本发明提供一种用于O2O线下调理的治疗行经腹泻的中药组合物，所述中药组合物由以下重量份组成：
党参1~5份，白术1~3份，茯苓1~2份，薏仁2~5份，吴茱萸1~4份，肉豆蔻1~3份，补骨脂1~3份，巴戟天1~2份，五味子1~2份，红枣1~3份，桂圆1~3份，莲子1~3份，桔梗1~2份。
优选地，所述中药组合物由以下重量份组成：
党参3~5份，白术2~3份，茯苓1~2份，薏仁3~5份，吴茱萸2~4份，肉豆蔻2~3份，补骨脂2~3份，巴戟天1~2份，五味子1~2份，红枣1~3份，桂圆2~3份，莲子1.5~3份，桔梗1.5~2份。
优选地，所述中药组合物由以下重量份组成：
党参3~4份，白术2.5~3份，茯苓1.5~2份，薏仁4~5份，吴茱萸2~3份，肉豆蔻2~2.5份，补骨脂2.5~3份，巴戟天1.5~2份，五味子1~1.8份，红枣2~3份，桂圆2.5~3份，莲子1.5~2.5份，桔梗1.5~1.8份。
优选地，所述中药组合物由以下重量份组成：
党参3份，白术2.5份，茯苓1.5份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.5份。
优选地，所述中药组合物由以下重量份组成：
党参3份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.6份。
优选地，所述中药组合物由以下重量份组成：
党参3份，白术2.5份，茯苓1.5份，薏仁5份，吴茱萸2.5份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.7份。
优选地，所述中药组合物由以下重量份组成：
党参3份，白术2.5份，茯苓1.5份，薏仁5份，吴茱萸2.5份，肉豆蔻2.5份，补骨脂3份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.8份。
优选地，所述中药组合物由以下重量份组成：
党参4份，白术3份，茯苓1.5份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子2.5份，桔梗1.6份。
优选地，所述中药组合物由以下重量份组成：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣3份，桂圆2.5份，莲子2.3份，桔梗1.6份。
优选地，所述中药组合物由以下重量份组成：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣3份，桂圆3份，莲子2.2份，桔梗1.6份。
优选地，所述中药组合物由以下重量份组成：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2.5份，补骨脂2.5份，巴戟天2份，五味子1.5份，红枣3份，桂圆3份，莲子2.1份，桔梗1.6份。
优选地，所述中药组合物由以下重量份组成：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸3份，肉豆蔻2份，补骨脂2.5份，巴戟天2份，五味子1.5份，红枣3份，桂圆2.5份，莲子2份，桔梗1.6份。
优选地，所述中药组合物由以下重量份组成：
党参4份，白术3份，茯苓2份，薏仁5份，吴茱萸2份，肉豆蔻2份，补骨脂3份，巴戟天1.5份，五味子1.8份，红枣3份，桂圆2.5份，莲子2份，桔梗1.7份。
优选地，所述中药组合物由以下重量份组成：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸3份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1.6份，红枣3份，桂圆3份，莲子2份，桔梗1.8份。
此外，为实现上述目的，本发明还提供一种用于O2O线下调理的治疗行经腹泻的中药组合物的制备方法，所述制备方法包含以下步骤：
A、将党参、白术、茯苓、薏仁、吴茱萸、肉豆蔻、补骨脂、巴戟天、五味子、红枣、桂圆加入8-12倍体积的水浸泡40分钟后煎煮，水开后煎煮30-60分钟，倒出煎液AA；
B、向煎液AA中加入2-3倍体积的水，煎煮 15-20分钟，倒出煎液BB；
C、将煎液AA和煎液BB混匀，静置澄清10-15分钟，吸取上清液，过滤形成滤液CC备用；
D、将所述煎液CC分装于洁净干燥灭菌的大口容器中，冷却后加盖密闭备用。
本发明以党参、白术、茯苓、薏仁、吴茱萸、肉豆蔻、补骨脂、巴戟天、五味子、红枣、桂圆为药物中各组份，通过它们协同作用起到益气健脾、温肾散寒、涩肠止泻和养血安神的功效，对于脾气虚弱、肾气虚弱等造成的行经腹泻，具有良好的治疗效果，而且安全、无毒无副作用，从而达到标本兼治的效果。
具体实施方式
下面结合具体实施例对本发明做进一步的详细说明，以下实施例是对本发明的解释，本发明并不局限于以下实施例。
本发明提供的用于O2O线下调理的治疗行经腹泻的中药组合物，所述中药组合物由以下重量份组成：
党参1~5份，白术1~3份，茯苓1~2份，薏仁2~5份，吴茱萸1~4份，肉豆蔻1~3份，补骨脂1~3份，巴戟天1~2份，五味子1~2份，红枣1~3份，桂圆1~3份，莲子1~3份，桔梗1~2份。
在上述组份中，党参具有补中益气、生津养血的功效；用于脾胃虚弱、气血两亏、久泻、体倦无力和食少口渴等症。
白术：具有补脾益胃、燥湿和中的功效；用于脾胃气弱、不思饮食、倦怠少气、虚胀泄泻和头晕自汗等症。
茯苓：既能健脾、又能渗湿，而且茯苓药性平和、不伤正气；具有利水渗湿和健脾的功效；用于脾虚所致的泄泻、带下等症。茯苓常与党参、白术、山药等配伍，有标本兼顾之效，为补肺脾、治气虚之辅佐药。
薏仁：具有利湿健脾、舒筋除痹和清热排脓的功效；用于泄泻带下等症。
吴茱萸：具有温中止痛和止呕健胃的功效；用于脏寒吐泻、脘腹胀痛、行经腹痛和五更泄泻等症。
肉豆蔻：具有温中下气和消食固肠的功效；用于心腹胀痛、虚泻冷痢、呕吐和宿食不消等症。
补骨脂：具有补肾助阳的功效；用于肾虚冷泻和腰膝冷痛等症。补骨脂的果实含挥发油约20%，主要为有机酸、甲基糖甙、碱溶性树脂、不挥发性萜类油和皂甙等成分。现代研究表明补骨脂能够缩短出血时间，减少出血量的效果；同时对子宫有明显的收缩作用。
巴戟天：味辛、甘，性微温，具有补肾阳、强筋骨和祛风湿的功效；用于少腹冷痛、宫冷不孕、月经不调和肾虚腰膝酸软等症。“巴戟天”又名“鸡肠薯”，属草科藤植物，为“四大南药”之一，可补肾阳、强筋骨、去除风湿、有提高免疫功能，降底血压和类皮质激素的作用，亨有“南国人参”之称。巴戟天与高良姜、肉桂、吴茱萸等药配伍使用，可以起到温肾调经的作用。现代研究表明巴戟天具有抗疲劳和增强免疫能力的作用。
五味子：味酸、甘，性温，归肺、心肾、经；具有收敛固涩、敛肺滋肾和生津收汗功效；用于久泻久痢、肺虚喘咳、口干作渴、自汗盗汗和劳伤羸瘦等症。现代药理研究表明，北五味子含有多种营养成分：如五味子素、苹果酸、柠檬酸、酒石酸、琥珀酸、脂肪油、挥发油、糖类、树脂、维生素C等，还含有钨、铁、锰、锌、磷等微量元素。五味子中含有五味子素，五味子素除了可以调节胃液分泌、兴奋子宫以外，还具有抑制细菌等病原微生物繁殖的功效。五味子树叶做为一种食材，具有食疗效果，长期食用可以起到温补益气、生津的作用，对于机体各种失衡状况的调理很有裨益。尤其是久病体虚之人，不宜滥用药物进行补益时，不妨利用它的食行进行食补。
红枣：味甘、性温，具有补中益气、养血安神和缓和药性的功效；用于脾虚、食少便溏和气血亏虚等症。常食大枣可治疗身体虚弱、神经衰弱、脾胃不和、消化不良和贫血消瘦等病症，有“日食三颗枣，百岁不显老”之说。现代的药理学表明，红枣含有蛋白质、脂肪、糖类、有机酸、维生素A、维生素C 、多种微量钙以及氨基酸等丰富的营养成份。枣中富含钙和铁，它们对防治骨质疏松、产后贫血有重要作用，中老年人更年期经常会骨质疏松，正在生长发育高峰的青少年和女性容易发生贫血，大枣对贫血患者有着十分理想的食疗作用，其效果通常是药物不能比拟的。红枣与党参、白术共用，更能补中益气、健脾胃，达到增加食欲、止泻的功效。
桂圆：具有补心脾、益气血、健脾胃和养肌肉功效；用于思虑伤脾、头昏失眠、心悸怔忡、病后虚赢或产后体虚以及由于脾虚所致之下血失血等症。现代医学实践证明桂圆还有美容、延年益寿之功效。
莲子：具有补脾止泻、止带、益肾涩精和养心安神的功效；用于脾虚泄泻、带下遗精和心悸失眠等症。
桔梗：桔梗升清，宣肺利气，用以载药上行。
服用上述药物，党参能够有效改善脾胃虚弱、气血两亏、久泻、体倦无力和食少口渴等症，有助于补中益气、生津养血；白术有助于补脾益胃、燥湿和中，能够有效改善脾胃气弱、不思饮食、倦怠少气、虚胀泄泻和头晕自汗等症；茯苓有助于健脾渗湿，能够有效改善脾虚所致的泄泻、带下等症；薏仁有助于利湿健脾、舒筋除痹和清热排脓，能够有效改善泄泻带下等症；吴茱萸有助于温中止痛和止呕健胃，能够有效改善脏寒吐泻、脘腹胀痛、行经腹痛和五更泄泻等症；肉豆蔻有助于温中下气和消食固肠的功效，能够有效改善心腹胀痛、虚泻冷痢、呕吐和宿食不消等症；补骨脂有助于补肾助阳，能够有效改善肾虚冷泻和腰膝冷痛等症；巴戟天有助于补肾阳、强筋骨和祛风湿，能够有效改善少腹冷痛、宫冷不孕、月经不调和肾虚腰膝酸软等症； 五味子有助于敛肺滋肾和生津收汗，能够有效改善久泻久痢、肺虚喘咳、口干作渴、自汗盗汗和劳伤羸瘦等症，五味子中含有五味子素，五味子素除了可以调节胃液分泌、兴奋子宫以外，还具有抑制细菌等病原微生物繁殖的功效；红枣有助于补中益气、养血安神和缓和药性，能够有效改善脾虚、食少便溏和气血亏虚等症；桂圆有助于补心脾、益气血、健脾胃和养肌肉，能够有效改善思虑伤脾、头昏失眠、心悸怔忡、病后虚赢或产后体虚以及由于脾虚所致之下血失血等症；莲子有助于补脾止泻、止带、益肾涩精和养心安神，能够有效改善脾虚泄泻、带下遗精和心悸失眠等症；桔梗：桔梗升清，宣肺利气，用以载药上行。通过上述药物组份的协同作用起到益气健脾、温肾散寒、涩肠止泻和养血安神的功效，对于脾气虚弱、肾气虚弱等造成的行经腹泻，具有良好的治疗效果，而且安全、无毒副作用，从而达到标本兼治的效果。
实施例1
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参3~5份，白术2~3份，茯苓1~2份，薏仁3~5份，吴茱萸2~4份，肉豆蔻2~3份，补骨脂2~3份，巴戟天1~2份，五味子1~2份，红枣1~3份，桂圆2~3份，莲子1.5~3份，桔梗1.5~2份。
实施例2
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参3~4份，白术2.5~3份，茯苓1.5~2份，薏仁4~5份，吴茱萸2~3份，肉豆蔻2~2.5份，补骨脂2.5~3份，巴戟天1.5~2份，五味子1~1.8份，红枣2~3份，桂圆2.5~3份，莲子1.5~2.5份，桔梗1.5~1.8份。
实施例3
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参3份，白术2.5份，茯苓1.5份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.5份。
实施例4
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参3份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.6份。
实施例5
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参3份，白术2.5份，茯苓1.5份，薏仁5份，吴茱萸2.5份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.7份。
实施例6
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参3份，白术2.5份，茯苓1.5份，薏仁5份，吴茱萸2.5份，肉豆蔻2.5份，补骨脂3份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.8份。
实施例7
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参4份，白术3份，茯苓1.5份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子2.5份，桔梗1.6份。
实施例8
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子2.4份，桔梗1.6份。
实施例9
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣3份，桂圆2.5份，莲子2.3份，桔梗1.6份。
实施例10
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣3份，桂圆3份，莲子2.2份，桔梗1.6份。
实施例11
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2.5份，补骨脂2.5份，巴戟天2份，五味子1.5份，红枣3份，桂圆3份，莲子2.1份，桔梗1.6份。
实施例12
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸3份，肉豆蔻2份，补骨脂2.5份，巴戟天2份，五味子1.5份，红枣3份，桂圆2.5份，莲子2份，桔梗1.6份。
实施例13
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参4份，白术3份，茯苓2份，薏仁5份，吴茱萸2份，肉豆蔻2份，补骨脂3份，巴戟天1.5份，五味子1.8份，红枣3份，桂圆2.5份，莲子2份，桔梗1.7份。
实施例14
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸3份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1.6份，红枣3份，桂圆3份，莲子2份，桔梗1.8份。
实施例15
用于O2O线下调理的治疗行经腹泻的中药组合物的组分如下：
党参4份，白术3份，茯苓2份，薏仁5份，吴茱萸2.5份，肉豆蔻2份，补骨脂3份，巴戟天2份，五味子1.8份，红枣3份，桂圆3份，莲子2份，桔梗1.9份。
以上实施例1-15中的用于O2O线下调理的治疗行经腹泻的中药组合物均采用下述方法制备：
所述制备方法包含以下步骤：
A、将党参、白术、茯苓、薏仁、吴茱萸、肉豆蔻、补骨脂、巴戟天、五味子、红枣、桂圆加入8-12倍体积的水浸泡40分钟后煎煮，水开后煎煮30-60分钟，倒出煎液AA；
B、向煎液AA中加入2-3倍体积的水，煎煮 15-20分钟，倒出煎液BB；
C、将煎液AA和煎液BB混匀，静置澄清10-15分钟，吸取上清液，过滤形成滤液CC备用；
D、将所述煎液CC分装于洁净干燥灭菌的大口容器中，冷却后加盖密闭备用。
采用上述中药组合物治疗行经腹泄的临床疗效总结：
一、一般资料：共治疗病人32例，均为女性；年龄12-16岁4例，17-30岁21例，30岁以上7例；病程最长者2年，最短者3个月。
二、诊断标准：
症状：具有典型的临床表现，符合行经腹泻等寻常性经期腹泻的诊断标准，一周内未做任何药物治疗。
三、疗效评定标准：
1、治愈：临床症状消失，3个月内不复发。
2、好转：临床症状减轻，有所改善，但仍需要治疗。
四、治疗结果：
经对32名患者按治疗方案给出的治疗方法，用本发明药物进行治疗，治疗后，经统计学处理，其中治愈30人，占62.5%，好转11人，占34.375%，无效1人，占3.125%，总有效率96.87%。
五、典型病例：
病例1：患者刘小姐，16岁，2014年9月来诊，因平时爱吃冷饮，来诊时的症状：经期腹泻，四肢逆冷，且小腹疼痛，腹泻为溏便，一日2次，浑身没有力气。给予本发明方药服用，每日2次，早晚各1次，服用第3天后腹痛明显减轻，大便逐步正常；五天后好转，连续服用2个月经周期，疼痛症状完全消失，排便也正常。随访半年，未见复发。
病例2：张小姐，28岁，2014年2月来诊，来诊时的症状：经期腹泻，且精神萎靡、浑身没有力气、昏昏欲睡、并且肚子胀痛、没有食欲；腹泻为水样便，一日多次。给予本发明方药服用，每日2次，早晚各1次，服用第4天后肚子胀痛明显减轻，食欲恢复正常；连续服用3个月经周期后排便正常、食欲正常和胀痛消失。随访一年，未见复发。
病例3：患者李小姐，45岁，2013年11月来诊，该患者平素体弱，病程较长，为2年，来诊时的症状：经期腹泻，面色苍白，腹泻较为严重，且进食之后完全排出，脱水，浑身没有力气，伴有小腹疼痛。给予本发明方药服用，每日2次，早晚各1次，服用第4天后腹泻明显减轻；连续服用4个月经周期后腹泻症状和腹痛症状完全消失。随访1年4个月，未见复发。
上述病例证明该方具有益气健脾、温肾散寒、涩肠止泻和养血安神的功效，对于脾气虚弱、肾气虚弱等造成的行经腹泻，具有良好的治疗效果，而且安全、无毒副作用，从而达到标本兼治的效果。
以上仅为本发明的优选实施例，并非因此限制本发明的专利范围，凡是利用本发明说明书所作的等效结构或等效流程变换，或直接或间接运用在其他相关的技术领域，均同理包括在本发明的专利保护范围内。

Claims (15)

  1. 一种用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参1~5份，白术1~3份，茯苓1~2份，薏仁2~5份，吴茱萸1~4份，肉豆蔻1~3份，补骨脂1~3份，巴戟天1~2份，五味子1~2份，红枣1~3份，桂圆1~3份，莲子1~3份，桔梗1~2份。
  2. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参3~5份，白术2~3份，茯苓1~2份，薏仁3~5份，吴茱萸2~4份，肉豆蔻2~3份，补骨脂2~3份，巴戟天1~2份，五味子1~2份，红枣1~3份，桂圆2~3份，莲子1.5~3份，桔梗1.5~2份。
  3. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参3~4份，白术2.5~3份，茯苓1.5~2份，薏仁4~5份，吴茱萸2~3份，肉豆蔻2~2.5份，补骨脂2.5~3份，巴戟天1.5~2份，五味子1~1.8份，红枣2~3份，桂圆2.5~3份，莲子1.5~2.5份，桔梗1.5~1.8份。
  4. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参3份，白术2.5份，茯苓1.5份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.5份。
  5. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参3份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.6份。
  6. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参3份，白术2.5份，茯苓1.5份，薏仁5份，吴茱萸2.5份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.7份。
  7. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参3份，白术2.5份，茯苓1.5份，薏仁5份，吴茱萸2.5份，肉豆蔻2.5份，补骨脂3份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子1.5份，桔梗1.8份。
  8. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参4份，白术3份，茯苓1.5份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣2份，桂圆2.5份，莲子2.5份，桔梗1.6份。
  9. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣3份，桂圆2.5份，莲子2.3份，桔梗1.6份。
  10. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1份，红枣3份，桂圆3份，莲子2.2份，桔梗1.6份。
  11. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸2份，肉豆蔻2.5份，补骨脂2.5份，巴戟天2份，五味子1.5份，红枣3份，桂圆3份，莲子2.1份，桔梗1.6份。
  12. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸3份，肉豆蔻2份，补骨脂2.5份，巴戟天2份，五味子1.5份，红枣3份，桂圆2.5份，莲子2份，桔梗1.6份。
  13. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参4份，白术3份，茯苓2份，薏仁5份，吴茱萸2份，肉豆蔻2份，补骨脂3份，巴戟天1.5份，五味子1.8份，红枣3份，桂圆2.5份，莲子2份，桔梗1.7份。
  14. 如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    党参4份，白术3份，茯苓2份，薏仁4份，吴茱萸3份，肉豆蔻2份，补骨脂2.5份，巴戟天1.5份，五味子1.6份，红枣3份，桂圆3份，莲子2份，桔梗1.8份。
  15. 一种如权利要求1所述的用于O2O线下调理的治疗行经腹泻的中药组合物的制备方法，其特征在于，所述制备方法包含以下步骤：
    A、将党参、白术、茯苓、薏仁、吴茱萸、肉豆蔻、补骨脂、巴戟天、五味子、红枣、桂圆加入8-12倍体积的水浸泡40分钟后煎煮，水开后煎煮30-60分钟，倒出煎液AA；
    B、向煎液AA中加入2-3倍体积的水，煎煮 15-20分钟，倒出煎液BB；
    C、将煎液AA和煎液BB混匀，静置澄清10-15分钟，吸取上清液，过滤形成滤液CC备用；
    D、将所述滤液CC分装于洁净干燥灭菌的大口容器中，冷却后加盖密闭备用。
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CN103394057A (zh) * 2013-07-24 2013-11-20 赵世明 一种治疗泄泻的中药组合物

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