WO2016180678A1 - Connector for a medical container - Google Patents
Connector for a medical container Download PDFInfo
- Publication number
- WO2016180678A1 WO2016180678A1 PCT/EP2016/059897 EP2016059897W WO2016180678A1 WO 2016180678 A1 WO2016180678 A1 WO 2016180678A1 EP 2016059897 W EP2016059897 W EP 2016059897W WO 2016180678 A1 WO2016180678 A1 WO 2016180678A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- section
- connector
- pinch
- medical container
- head section
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/18—Arrangements for indicating condition of container contents, e.g. sterile condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
- A61J1/1425—Snap-fit type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/20—Closure caps or plugs for connectors or open ends of tubes
Definitions
- the invention relates to a connector for a medical container according to the preamble of claim 1 .
- a connector of this kind comprises a connector element to be attached to the medical container for providing a port to the medical container.
- the connector element comprises a head section and a pinch-off section adjoining the head section, wherein the head section comprises an opening and the pinch-off section encloses an inner lumen being in fluid connection with the opening of the head section for providing a fluid path through the connector element.
- the opening of the head section can be closed by a closure element which is attachable to the head section of the connector element such that, when the closure element is attached to the head section, the fluid path through the connector element is blocked.
- a membrane element can be placed in-between the closure element and the head section of the connector element. The membrane element can be pierced by a needle of a delivery device, for example a syringe, for injecting a medical fluid into the medical container or for extracting a medical fluid from the medical container.
- the connector when attached to a medical container, shall allow for filling the medical container with a medical fluid, for example a fluid for the parenteral feeding of a patient such as a glucose solution, a fat solution or an amino acid solution.
- a medical fluid for example a fluid for the parenteral feeding of a patient such as a glucose solution, a fat solution or an amino acid solution.
- the medical container herein may be filled for example by a medical supplier (which may be the container manufacturer) or in a pharmacy of a hospital and shall subsequently be prepared such that it can be stored and delivered for a later usage.
- a filling spike of a filling station may be inserted into the connector element prior to attaching the closure element to the connector element.
- the connector element is pinched-off at its pinch-off section such that the fluid path through the connector element is closed and fluid cannot exit from the medical container through the connector element.
- the connector element is sealed towards the outside such that the pinching of the pinch-off section can be released and the medical container can be stored or delivered to a hospital or the like.
- the closure element When using the medical container on a patient, the closure element may be opened, for example by breaking-off a break-off part.
- a user hence may access the connector element by piercing the membrane element placed in-between the head section of the connector element and the closure element using for example a needle of a syringe.
- fluid may be extracted from the medical container, or fluid may be added to the medical container in order to for example add further components such as vitamins or other nutritional components or the like to the fluid contained in the container.
- the needle comes into contact with the pinch-off section of the connector element, e.g. because the pinch-off section could have a reduced wall thickness in order for it to be deformable for pinching off the connector element. If the needle were to come into contact with the pinch-off section, there may be a risk of damaging the pinch-off section, possibly rendering the medical container unsterile and hence useless. It is clear that the invention relates to any kind of pinch-off section being in the danger to be damaged by the needle. Reasons therefore may the thickness of the wall, selection of material of the wall or other. The invention will be described by a connector with thinner walls at the pinch-off section in way of example only.
- a deflection element which extends from the head section towards the inner lumen of the pinch-off section for deflecting a needle of a delivery device when piercing the membrane element.
- the deflection element serves to guide the needle towards the inner lumen of the pinch- off section when piercing the membrane element by means of the needle.
- the deflection element herein is shaped such that the risk for damaging the pinch-off section by means of the needle, when introducing it into the connector element, is reduced, in particular in that the needle is guided such that it would not come into contact with the walls of the pinch-off section.
- the deflection element reaches into the inner lumen of the pinch-off section.
- the deflection element hence extends from the head section and reaches into the inner lumen enclosed by the pinch-off section.
- the deflection element is formed as a comparatively rigid piece and in particular may be formed in one piece with the head section.
- the deflection element may reach into the inner lumen of the pinch-off section, it extends into the inner lumen of the pinch-off section only that far that a pinching off of the pinch-off section is not hindered. In particular, the deflection element does not extend into a region of the pinch-off section in which (typically) a pinching off shall take place.
- the deflection element may for example have the shape of a cylindrical pipe.
- the deflection element extends from the head section and provides a guide for the needle such that the needle cannot come into contact with walls of the pinch-off section when inserting it into the connector element.
- the deflection element for example having the shape of a cylindrical pipe, comprises a guide opening through which the needle may be guided.
- the guide opening longitudinally extends along an insertion direction along which the needle of the delivery device can be inserted into the connector element.
- the guide opening beneficially is aligned with the opening of the head section of the connector element through which the needle of the delivery device is inserted into the connector element.
- the deflection element in one embodiment, is arranged at a radial distance to the walls of the pinch-off section.
- the deflection element hence, is arranged radially inside the pinch-off section such that it provides a guide inside of the pinch-off section.
- the walls of the pinch-off section are arranged radially outside of the deflection element at a radial distance to the deflection element, a needle guided by the deflection element cannot come into contact with the walls of the pinch-off section such that the risk for damaging the walls of the pinch-off section when inserting the needle into the connector element is greatly reduced.
- the connector element may for example have the shape of a ship-shaped conus.
- the connector element hence has a general ship shape and comprises for example a fastening section which can be inserted in-between foils of the medical container such that the connector element via its fastening section can be welded to the foils of the medical container (having the shape of for example a flexible bag).
- the fastening section has a rather rigid shape and has an increased wall thickness in comparison to walls of the pinch-off section. Because the walls of the pinch-off section have a reduced wall thickness (at least in particular regions), the pinch-off section is flexibly deformable for pinching-off the fluid path through the connector element after filling the medical container.
- the closure element may for example comprise an attachment section attachable to the head section of the connector element and a break-off part connected to the attachment section along a break line along which the break-off part can be broken off the attachment section.
- the closure element may for example be attached to the connector element after filling of the medical container such that, with the closure element attached, the medical container can be stored or delivered for example to a hospital.
- a user wants to access the medical container for example to inject a medical fluid into the medical container or to extract a medical fluid from the medical container, he breakes off the break-off part and hence opens the connector element such that the membrane element placed in-between the closure element and the connector element is accessible from the outside for piercing it by means of a needle of a suitable delivery device, for example a syringe or the like.
- a suitable delivery device for example a syringe or the like.
- Fig. 1 shows a schematic view of a medical container in the shape of a three- chamber flexible bag comprising three connectors
- Fig. 2A shows a front view of a connector element of a connector
- Fig. 2B shows a side view of the connector element
- Fig. 2C shows a top view of the connector element
- Fig. 3A shows a sectional view along line A-A according to Fig. 2A;
- Fig. 3B shows a sectional view along line B-B according to Fig. 2B
- Fig. 4A shows a sectional view of the connector element with a closure element attached to a head section of the connector element
- Fig. 4B shows the view of Fig. 4A, with a break-off part broken off the closure element and with a needle of a delivery device inserted into the connector element.
- Fig. 1 shows in a schematic view a medical container 1 in the shape of a flexible bag made of thin, flexible foils welded to each other.
- the medical container 1 in the shown embodiment, comprises three chambers 10-12 for receiving medical fluids, for example for the parenteral feeding of a patient.
- the chambers 10-12 herein may contain different medical fluids, for example a glucose solution, a fat solution and an amino acid solution, wherein the chambers 10-12 may be connected via tearable seams which may be torn open to bring the chambers 10-12 in fluid connection with each other for mixing the different solutions with each other prior to delivering them to a patient.
- Each chamber 10-12 is associated with a connector 2, as shown in Fig. 1 .
- the chambers 10-12 herein are filled via their respective connectors 2, for example by a medical supplier or within a hospital pharmacy or the like.
- the connectors 2 are closed such that the chambers 10-12 are sealed towards the outside and the medical container can be stored or delivered for use on a patient.
- the mixing of the different solutions contained in the chambers 10-12 then takes place immediately prior to injecting the medical fluid of the medical container 1 to a patient in that a user, for example a nurse, tears open the tearable seams in-between the chambers 10-12 such that the solutions contained in the chambers 10-12 can mix within the medical container 1 .
- a user for example a nurse
- each connector 2 comprises a connector element 20, a closure element 21 and a membrane element 22 placed in-between the closure element 21 and the connector element 20.
- the connector element 20 comprises a fastening section 200 which can be inserted in- between foils of the medical container 1 for welding the connector element 20 to the medical container 1 .
- the fastening section 200 is adjoined by a pinch-off section 201 , which terminates in a head section 202.
- the closure element 21 is attached via an attachment section 210 in a form locking manner by engaging with a locking rim 203 of the head section 202.
- the closure element 21 when it is attached to the head section 202 of the connector element 20, closes off an opening 204 in the head section 202.
- the closure element 21 comprises a head section 21 1 adjoining the attachment section 210 and being connected, in the state of Fig. 4A, to a break-off part 214 along a circumferential break line 213.
- the connector elements 20 of the connectors 2 are placed in-between the foils of the medical container 1 and are welded to the foils when forming the chambers 10-12 of the medical container 1.
- the chambers 10-12 of the medical container 1 are filled for example by a medical supplier or in a pharmacy of a hospital by inserting a filling spike into the respective connector elements 20 and by filling the chambers 10-12 with medical solutions as desired.
- the respective connector element 20 is pinched- off at its pinch-off section 201 by applying a suitable clamping device.
- the connector element 20 is flexibly deformable at its pinch-off section 201 , which comprises a reduced wall thickness W1 in comparison to other sections of the connector element 20, for example in comparison to a wall thickness W2 of the walls 208 of the fastening section 201 , as depicted in Fig. 3A.
- the medical container 1 can be stored or can be delivered to a place of usage, for example to a hospital.
- a user may break off one or multiple of the break-off parts 214 of the closure elements 21 of the connectors 2 and may insert a needle 30 of a suitable delivery device 3, for example a syringe, into an opening 212 within the head section 21 1 of the closure element 21 and may pierce the membrane element 22 held in-between the closure element 21 and the connector element 20.
- a medical fluid may be added to the medical container 1 or a medical fluid may be extracted from the medical container 1.
- the medical container 1 comprises different solutions for the parenteral feeding of a patient, further components such as vitamins or the like may be added via one of the connectors 2 prior to administering the (mixed) solutions to a patient.
- the membrane element 22 is constituted as a self-sealing membrane which, after removing the needle 30 of the delivery device 3, seals itself such that the connector element 20 is closed in a fluid-tight manner towards the outside.
- a deflection element 205 having the shape of a cylindrical pipe is provided which extends from the head section 202 towards the inner lumen L of the pinch-off section 201 , as shown in the sectional views of Fig. 3A and 3B.
- the deflection element 205 comprises a longitudinal guide opening 206 which is aligned along the insertion direction I with the opening 204 of the head section 202 such that the needle 30 of a delivery device 3 is guided via the deflection element 205 towards the inner lumen L of the pinch-off section 201 , as shown in Fig. 4B.
- the deflection element 205 in the shape of a cylindrical pipe is formed in one piece with the connector element 20 and has a rigid shape such that a needle 30 pinching onto the inner circumferential face of the guide opening 206 is deflected and guided in the insertion direction I or is stopped such that it cannot come into contact with the outer walls 207 of the pinch-off section 201. Hence, the risk that the walls 207 of the pinch-off section may be damaged by the needle 30 is reduced.
- the deflection element 205 extends from the head section 202 in the insertion direction I and reaches into the inner lumen L of the pinch-off section 201 . It herein is placed inside the pinch-off section at a radial distance to the walls 207.
- the deflection element 205 reaches into the inner lumen L of the pinch-off section 201 , it does not extend through the pinch-off section 201 and in particular reaches into the inner lumen L only that far that a reliable pinching of the pinch-off section 201 is not hindered.
- the connector element 20, as visible from the top view of Fig. 2C, has the general shape of a ship, with the fastening section 200 reducing in width towards both sides along a horizontal direction H such that the fastening section 200 may be reliably welded to the foils of the medical container 1 for providing a fluid-tight transition.
- the pinch-off section 201 likewise does not have a circular cross-section, but is formed such that it may be reliably pinched-off in a pinch-off direction P (see Fig. 3A) for closing off the fluid path through the connector element 20, as it is described for example in WO 2004/084793 A1.
- the invention is not limited to the embodiments described above, but may be implemented in an entirely different fashion.
- the invention is not limited to three-chamber medical bags, but may be applied to any sort of medical containers, having one, two or more chambers.
- the medical container not necessarily is flexible, but may also have a rigid shape, such as the shape of a bottle or the like.
- Each chamber of the medical container may be provided with one, two or more connector(s) according to the present invention. It is also understood that the medical container may provided with a mixture of both, inventive connector(s) and connector(s)/port(s) of the prior art, depending of the needs for the use of said container.
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16721772.8A EP3294255B1 (en) | 2015-05-08 | 2016-05-03 | Connector for a medical container |
PL16721772T PL3294255T3 (pl) | 2015-05-08 | 2016-05-03 | Łącznik do pojemnika medycznego |
US15/572,550 US20180104148A1 (en) | 2015-05-08 | 2016-05-03 | Connector for a medical containerr |
CN201680026621.4A CN107820421B (zh) | 2015-05-08 | 2016-05-03 | 用于医用容器的连接器 |
KR1020177032229A KR102593071B1 (ko) | 2015-05-08 | 2016-05-03 | 의료 용기용 커넥터 |
ES16721772T ES2794829T3 (es) | 2015-05-08 | 2016-05-03 | Conector para un recipiente médico |
HK18108673.7A HK1249005A1 (zh) | 2015-05-08 | 2018-07-04 | 用於醫用容器的連接器 |
US18/217,804 US20230338236A1 (en) | 2015-05-08 | 2023-07-03 | Connector for a medical container |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15166901 | 2015-05-08 | ||
EP15166901.7 | 2015-05-08 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US15/572,550 A-371-Of-International US20180104148A1 (en) | 2015-05-08 | 2016-05-03 | Connector for a medical containerr |
US18/217,804 Continuation US20230338236A1 (en) | 2015-05-08 | 2023-07-03 | Connector for a medical container |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2016180678A1 true WO2016180678A1 (en) | 2016-11-17 |
Family
ID=53054957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2016/059897 WO2016180678A1 (en) | 2015-05-08 | 2016-05-03 | Connector for a medical container |
Country Status (8)
Country | Link |
---|---|
US (2) | US20180104148A1 (zh) |
EP (1) | EP3294255B1 (zh) |
KR (1) | KR102593071B1 (zh) |
CN (1) | CN107820421B (zh) |
ES (1) | ES2794829T3 (zh) |
HK (1) | HK1249005A1 (zh) |
PL (1) | PL3294255T3 (zh) |
WO (1) | WO2016180678A1 (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023148320A1 (de) * | 2022-02-04 | 2023-08-10 | Fresenius Kabi Deutschland Gmbh | Infusionsbeutel sowie verfahren zu dessen herstellung |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10313760B3 (de) * | 2003-03-27 | 2004-06-03 | Fresenius Kabi Deutschland Gmbh | Konnektor für medizinische Flüssigkeiten enthaltende Verpackungen und Verpackung für medizinische Flüssigkeiten |
US20050059951A1 (en) * | 2003-09-12 | 2005-03-17 | Young Harvey Theodore | Flexible container with a flexible port and method for making the same |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5088996A (en) * | 1984-04-16 | 1992-02-18 | Kopfer Rudolph J | Anti-aerosoling drug reconstitution device |
CN1179983A (zh) * | 1997-06-03 | 1998-04-29 | 王坤山 | 由弹性活门式瓶塞和穿刺针组成的医用装置 |
DE19958952B4 (de) * | 1999-12-08 | 2004-05-27 | Fresenius Kabi Deutschland Gmbh | Entnahmesystem für medizinische Lösungen und Behälter mit einem derartigen Entnahmesystem |
FR2821827B1 (fr) * | 2001-03-07 | 2003-06-13 | Biodome | Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif |
DE10223560B4 (de) * | 2002-05-27 | 2006-01-19 | Fresenius Kabi Deutschland Gmbh | Konnektor für medizinische Flüssigkeiten enthaltende Verpackungen und Verpackung für medizinische Flüssigkeiten |
DE10348016B4 (de) * | 2003-10-15 | 2007-05-03 | Fresenius Kabi Deutschland Gmbh | Konnektor für medizinische Flüssigkeiten enthaltende Verpackungen und Verpackung für medizinische Flüssigkeiten |
US7455663B2 (en) * | 2006-08-23 | 2008-11-25 | Medtronic Minimed, Inc. | Infusion medium delivery system, device and method with needle inserter and needle inserter device and method |
GB2461085B (en) * | 2008-06-19 | 2012-08-29 | Cilag Gmbh Int | Injection device |
CN102573754B (zh) * | 2009-10-26 | 2014-07-02 | 株式会社Jms | 医疗用容器的连接器组 |
EP2353629A1 (de) * | 2010-02-08 | 2011-08-10 | Fresenius Kabi Deutschland GmbH | Konnektor für medizinischen Wirkstoff enthaltende Behälter |
CN202497451U (zh) * | 2012-04-06 | 2012-10-24 | 重庆莱美药业股份有限公司 | 旋进预装式加药器上使用的推动装置 |
-
2016
- 2016-05-03 CN CN201680026621.4A patent/CN107820421B/zh active Active
- 2016-05-03 KR KR1020177032229A patent/KR102593071B1/ko active IP Right Grant
- 2016-05-03 ES ES16721772T patent/ES2794829T3/es active Active
- 2016-05-03 WO PCT/EP2016/059897 patent/WO2016180678A1/en active Application Filing
- 2016-05-03 PL PL16721772T patent/PL3294255T3/pl unknown
- 2016-05-03 EP EP16721772.8A patent/EP3294255B1/en active Active
- 2016-05-03 US US15/572,550 patent/US20180104148A1/en not_active Abandoned
-
2018
- 2018-07-04 HK HK18108673.7A patent/HK1249005A1/zh unknown
-
2023
- 2023-07-03 US US18/217,804 patent/US20230338236A1/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10313760B3 (de) * | 2003-03-27 | 2004-06-03 | Fresenius Kabi Deutschland Gmbh | Konnektor für medizinische Flüssigkeiten enthaltende Verpackungen und Verpackung für medizinische Flüssigkeiten |
US20050059951A1 (en) * | 2003-09-12 | 2005-03-17 | Young Harvey Theodore | Flexible container with a flexible port and method for making the same |
Also Published As
Publication number | Publication date |
---|---|
US20180104148A1 (en) | 2018-04-19 |
CN107820421A (zh) | 2018-03-20 |
KR20180004144A (ko) | 2018-01-10 |
EP3294255A1 (en) | 2018-03-21 |
PL3294255T3 (pl) | 2020-07-27 |
EP3294255B1 (en) | 2020-04-01 |
KR102593071B1 (ko) | 2023-10-23 |
US20230338236A1 (en) | 2023-10-26 |
HK1249005A1 (zh) | 2018-10-26 |
ES2794829T3 (es) | 2020-11-19 |
CN107820421B (zh) | 2021-04-02 |
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