WO2016167502A1 - Composition permettant d'augmenter la prise alimentaire et de favoriser la croissance, et son procédé de préparation - Google Patents

Composition permettant d'augmenter la prise alimentaire et de favoriser la croissance, et son procédé de préparation Download PDF

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Publication number
WO2016167502A1
WO2016167502A1 PCT/KR2016/003473 KR2016003473W WO2016167502A1 WO 2016167502 A1 WO2016167502 A1 WO 2016167502A1 KR 2016003473 W KR2016003473 W KR 2016003473W WO 2016167502 A1 WO2016167502 A1 WO 2016167502A1
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WIPO (PCT)
Prior art keywords
weight
ciproheptadine
feed intake
composition
feed
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PCT/KR2016/003473
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English (en)
Korean (ko)
Inventor
권혁천
채병조
최형규
정은용
Original Assignee
권혁천
(주)이엘티사이언스
채병조
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Publication of WO2016167502A1 publication Critical patent/WO2016167502A1/fr

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry

Definitions

  • the present invention is a feed intake enhancer and growth promoter composition, more specifically, by adding the feed intake enhancer and growth accelerator composition to the feed consumed by livestock, so that the appetite is reduced due to disease and stress, feed intake is reduced
  • the present invention relates to a feed intake enhancing and growth promoting agent composition and a method for producing the same, which are capable of restoring or increasing feed intake of livestock to promote the growth and health of the livestock.
  • the purpose of the livestock industry is to raise livestock such as chickens, pigs, cows, etc. to produce livestock products such as eggs, meat, and milk to promote human health.
  • livestock products such as chickens, pigs, cows, etc.
  • livestock products such as eggs, meat, and milk to promote human health.
  • the size of the livestock industry has also increased and specialized, and as the import and export of livestock products between countries has been liberalized, efforts to secure competitiveness by increasing productivity are required.
  • Feed ingestion enhancers have been used to increase the food intake by feeding the palatal substances that stimulate feed intake to increase the amount of feed intake and thereby increase the productivity has been used flavors, sweeteners, acidulants and the like.
  • Feed intake is an important indicator for improving livestock productivity. Increasing feed intake for livestock can result in more meat and livestock products in a shorter period of time. These feed intakes are affected by a variety of factors, including the health of the livestock, the breeding environment, age and sex, and the quality and palatability of the feed. In particular, in order to maintain high quality and palatability of feed, fresh and savory raw materials should be used, which leads to an increase in feed prices and lowers price competitiveness. Therefore, farms or feed mills prefer to use inexpensive by-products. have. Therefore, some flavors, sweeteners and acidifiers are added to the feed for the purpose of improving productivity by optimizing or maximizing the feed intake of livestock, which is an economic animal. Proper use of these feed intake enhancers makes it possible to increase the ratio of by-products with low palatability but low palatability, resulting in economical design for feed blending and increased productivity through increased feed intake, resulting in increased productivity. Can achieve an improvement.
  • physiological phenomena may cause anorexia to reduce food intake at certain times (high summer season, disease occurrence, weaning, moving, feed replacement, etc.). Even if the palatability of the feed is increased by using a sweetener or an acidulant, there is a problem that the feed intake cannot be recovered or increased.
  • the present invention is invented to solve the problems of the conventional feed intake enhancer as described above, feed intake in order to increase the feed intake of livestock feed is significantly reduced due to diseases or stress, feed intake to improve productivity It is an object of the present invention to provide a growth and growth promoter composition and a method of preparing the same.
  • the present invention is 0.2 ⁇ 5.0% by weight of the hawthorn extract, 2.0 ⁇ 20.0% by weight of ciproheptadine dispersion, 1.0 ⁇ 5.0% by weight of liquid paraffin, 25.0 ⁇ 50.0% by weight zeolite, and roasted rice husk powder It is characterized by being formed by mixing 25.0 ⁇ 71.8% by weight.
  • the present invention comprises the first step of preparing a hawthorn extract by putting the dried hawthorn powder in 70% ethanol solution and adding ganbanite to extract at room temperature for 3 to 7 days and then concentrated under reduced pressure the filtered solution; Dissolving ciproheptadine with a mixture of ethanol, polyethylene glycol, and polysorbate 80 to adsorb to silicon dioxide to prepare a ciproheptadine dispersion; 0.2 to 5.0% by weight of hawthorn extract, 2.0 to 20.0% by weight of ciproheptadine dispersion, 1.0 to 5.0% by weight of liquid paraffin, 25.0 to 50.0% by weight of zeolite, and 25.0 to 71.8% by weight of roasted rice husk powder were added to the mixer.
  • the third step of forming a composition by mixing characterized by including.
  • the feed intake promotion and growth promoter composition of the present invention by providing the feed intake promotion and growth promoter composition of the present invention and a method for manufacturing the same, the feed intake can be effectively restored or enhanced by adding to the feed to the animals whose appetite is deteriorated due to disease or stress. It has the effect of promoting livestock growth and improving productivity.
  • 1 is a block diagram showing a manufacturing process of the composition according to the present invention.
  • the present invention is 0.2 to 5.0% by weight of the hawthorn extract, ciproheptadine dispersion 2.0 to 20.0% by weight, liquid paraffin 1.0 to 5.0% by weight, zeolite 25.0 to 50.0% by weight, and roasted rice husk powder 25.0 to 71.8% by weight It is characterized by being formed.
  • Feed intake enhancement and growth promoting agent according to the present invention includes the acid extract and ciproheptadine as an active ingredient, in particular composed of a composite composition composed of acid extract, ciproheptadine, zeolite, liquid paraffin and roasted chaff powder
  • the feed intake improvement effect is insufficient by adding to the feed at a specific time such as high temperature during the summer when the feed intake decreases or when a disease occurs or the reason, movement, and stress.
  • the hawthorn extract used as a main ingredient in the present invention extracts dried fruits of hawthorn (Crataegus pinnatifida bunge) with ethanol or water and concentrates the filtered solution under reduced pressure to promote the secretion of various digestive enzymes as a dry powder to help digestion and immunity. It has excellent reinforcing effect, strengthens anti-medical force, and is effective in preventing indigestion, enteritis, hepatitis, jaundice and high blood pressure in human body because of its excellent effect on inhibiting liver cancer and lowering blood pressure.
  • Cyproheptadine which is used as a main ingredient in the present invention, is a dibenzocycloheptene piperidine-based antihistamine. It is used for the treatment of gall bladder, vasomotor edema, and also for the treatment of anorexia and weight loss.
  • the anti-histamine pharmacological mechanism of ciproheptadine is sporoheptadine binds to the histamine H1 receptor to exhibit an antihistamine effect, and the appetite promoting mechanism is that ciproheptadine competitively inhibits the action of serotonin.
  • serotonin binds to the 5-HT2C serotonin receptor in the satiety center and feels satiety.
  • Ciproheptadine binds to the satiety center instead of serotonin, thereby inhibiting the action of serotonin, making it less likely to continue eating. It helps to help.
  • Zeolite used as an excipient in the present invention is an aluminum silicate hydrate of alkali and alkaline earth metals, which does not cause physical and chemical reactions with active ingredients, has excellent preservation and low moisture content, and is used as an excipient of feed additives to maintain stability. .
  • Roasted rice husk powder used as an excipient in the present invention is a powder crushed to 50 to 100 mesh size after firing rice hull (Rice hull) is a preservative without causing a physical chemical reaction with the active ingredients and has a low moisture content feed additive It is used as an excipient of.
  • Liquid paraffin used as a stabilizer in the present invention is a mixture of hydrocarbons obtained from petroleum, colorless, odorless, tasteless to improve the blending and uniformity in the manufacture of feed additives without improving the active ingredient and to improve the stability of the product It is used as an additive for.
  • the main component of the hawthorn extract used in the present invention it is preferable to use 0.2 to 5.0% by weight based on the total weight of the composition.
  • Ciproheptadine which is a main component of the feed intake enhancing and growth promoter composition, preferably contains 0.1 to 1.0 wt% based on the total weight of the composition.
  • ciproheptadine When the ciproheptadine is less than 0.1% by weight, feed intake enhancement and growth promoting effects are insufficient, and when it is 1.0% by weight or more, it is not preferable to be applied to livestock which is an expensive animal compared to the effect.
  • Fluid paraffin, a stabilizer used in the present invention is preferably used 1.0 to 5.0% by weight based on the total weight of the composition.
  • liquid paraffin When the liquid paraffin is 1.0% by weight or less, it causes a problem in the stability of the composition, and when 5.0% by weight or more is not preferable due to the excessive use.
  • Zeolite as an excipient in the feed intake promotion and growth accelerator composition according to the present invention is preferably used 25.0 ⁇ 50.0% by weight based on the total weight of the composition.
  • the zeolite When the zeolite is 25.0 wt% or less, it causes a problem in the stability of the composition (uniformity maintenance), and when it is 50.0 wt% or more, it also causes a problem in the stability of the composition, which is not preferable.
  • Baked chaff powder is an excipient used in the present invention is preferably used 25.0 ⁇ 71.8% by weight based on the weight of the total composition.
  • the roasted rice husk powder When the roasted rice husk powder is 25.0% by weight or less, it causes a problem in the stability (uniformity) of the composition, and when 71.8% by weight or more also causes a problem in the stability of the composition is not preferable.
  • Such a method for preparing feed intake promotion and growth promoter compositions according to the present invention is as follows.
  • the first step (S100) is a process for manufacturing the hawthorn extract, each 250g dried hawthorn in 1,000ml of 70% ethanol and put about 20g of ganban stone and left at room temperature for 3 to 7 days and then filtered through a 20 mesh sieve Then, concentrated under reduced pressure to prepare an hawthorn extract.
  • the extraction time in the first step (S100) hawthorn extract manufacturing step is preferably 3 to 7 days, if less than 3 days is not preferable because the extraction state is insufficient and more than 7 days no extraction occurs. .
  • the second step 200 is a process for preparing a ciproheptadine dispersion in order to improve the mixing, uniformity and bioavailability of ciproheptadine, 100ml of anhydrous ethanol and polyethyleneglycol-400 (Polyethyleneglycol-400) Add 100 g, start stirring at a speed of 120 rpm, add 11 g of ciproheptadine hydrochloride and stir for 60 minutes to completely dissolve. Then, add 10 g of polysorbate 80 (Polysorbate 80), lower the stirring speed to 30 rpm, and stir for 30 minutes.
  • the second step (S200) ciproheptadine dispersion manufacturing process it is preferable to use 30.0 to 60.0% by weight, based on the weight of the total ciproheptadine solution of the anhydrous ethanol and silver, when 30.0% by weight or less.
  • the amount of polyethylene glycol 400 is relatively reduced, which is not preferable because of insufficient ciproheptadine dissolving effect.
  • the polyethylene glycol 400 is preferably used 25.0 to 62.5% by weight, based on the total weight of ciproheptadine solution, when 25.0% by weight or less.
  • the amount of anhydrous ethanol is relatively decreased, so the ciproheptadine dissolution effect is insufficient, which is not preferable.
  • polysorbate 80 is preferably used 2.5 to 10.0% by weight based on the total weight of ciproheptadine solution, if 2.5% by weight or less If the stability of roheptadine is lower than 10% by weight, it is not preferable to use excessively.
  • the third step (S300) is a step of preparing the final composition, 0.2 ⁇ 5.0% by weight of the hawthorn extract prepared in the first step (S100) and the ciproheptadine dispersion prepared in step (S200) 2.0 ⁇ 20.0 After the weight%, zeolite 25.0 ⁇ 50.0% by weight and roasted rice husk powder 20.0 ⁇ 71.8% by weight, respectively, into the mixer and mixed with liquid paraffin 1.0 ⁇ 5.0% by weight while mixing for 10 to 30 minutes at 120rpm to form a composition .
  • Table 1 ingredient 1 kg Hawthorn extract 5 g Ciproheptadine Dispersion 100 g Liquid paraffin 20 g Zeolite 400 g Grilled chaff powder 475 g
  • the process of preparing a feed intake enhancement and growth promoter composition is as follows. Sansa extract and ciproheptadine dispersion, zeolite and roasted rice husk powder in each order in the mixer, and then mixed by spraying liquid paraffin for 10 to 30 minutes at a speed of 120rpm to prepare a feed intake enhancement and growth promoter composition.
  • the process of preparing a feed intake enhancement and growth promoter composition is as follows.
  • the hawthorn extract, zeolite and roasted rice husk powder were put into the mixer in order, and then mixed with the liquid paraffin for 10 to 30 minutes at a speed of 120 rpm to prepare a feed ingestion and growth promoter composition.
  • Ciproheptadine Dispersion 100 g Liquid paraffin 20 g Zeolite 400 g Grilled chaff powder 475 g
  • the process of preparing a feed intake enhancement and growth promoter composition is as follows.
  • the ciproheptadine dispersion, zeolite and roasted rice husk powder are put into a mixer in order, and then mixed at a speed of 120 rpm for 10 to 30 minutes while spraying liquid paraffin to prepare a feed ingestion and growth promoter composition.
  • Table 4 ingredient 1 kg Hawthorn extract 5 g Ciproheptadine Dispersion 100 g Zeolite 400 g Grilled chaff powder 475 g
  • the process of preparing a feed intake enhancement and growth promoter composition is as follows. Sansa extract, ciproheptadine dispersion, zeolite and roasted rice husk powder are put in a mixer in order, and then mixed for 10 to 30 minutes at a speed of 120 rpm to prepare a feed ingestion and growth promoter composition.
  • the process of preparing a feed intake enhancement and growth promoter composition is as follows. Sansa extract, ciproheptadine dispersion, and roasted rice husk powder were put into the mixer in order, and then mixed with the liquid paraffin for 10 to 30 minutes at a speed of 120 rpm to prepare a feed ingestion and growth promoter composition.
  • Table 6 ingredient 1 kg Hawthorn extract 5 g Ciproheptadine Dispersion 100 g Liquid paraffin 20 g Zeolite 400 g
  • the process of preparing a feed intake enhancement and growth promoter composition is as follows. Sansa extract, ciproheptadine dispersion and zeolite were put into the mixer in order, respectively, and mixed with the liquid paraffin for 10 to 30 minutes at a speed of 120 rpm to prepare a feed ingestion and growth promoter composition.
  • Feed intake was the highest in the Example 1 feed group was increased by 15.1% compared to the control group, the Example 2 feed group was increased 4.5%, Example 3 feed group was increased by 7.9%, respectively.
  • the weight gain was increased by 17.7% in Example 1, 5.1% in Example 2, and 8.6% in Example 3, respectively.
  • Feed intake, weight gain and feed rate of each example composition are shown in Table 8 below.
  • compositions of Examples 1, 2, and 3 were in good condition of maintaining uniformity, and the contents of the active ingredients for each sample were very stable, but Examples 4, 5, and 6 were poor in uniformity. In addition, the active ingredient content is also significantly reduced compared to Examples 1, 2, 3 was poor in stability.
  • the present invention is 0.2 to 5.0% by weight of the hawthorn extract, ciproheptadine dispersion 2.0 to 20.0% by weight, liquid paraffin 1.0 to 5.0% by weight, zeolite 25.0 to 50.0% by weight, and roasted rice husk powder 25.0 to 71.8% by weight
  • the feed intake can be effectively restored or promoted to promote the growth of the animals and improve productivity. It is an invention that has the effect of making it possible to be a very useful invention and an invention of very high industrial applicability.

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Health & Medical Sciences (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne une composition permettant d'augmenter la prise alimentaire et de favoriser la croissance et son procédé de préparation, la composition étant ajoutée à un aliment pour animaux, qui est ensuite acheminé au bétail dont l'appétit est réduit à cause d'une maladie ou du stress, ce qui permet de récupérer ou d'augmenter efficacement la quantité de la prise alimentaire, favorisant ainsi la croissance du bétail et améliorant la productivité. Pour ce faire, la composition est préparée en mélangeant de 0,2 à 5,0 % en poids d'un extrait de Crataegus pinnatifida, de 2,0 à 20,0 % en poids d'un dispersant cyproheptadine, de 1,0 à 5,0 % en poids de paraffine liquide, de 25,0 à 50,0 % en poids de zéolite, et de 25,0 à 71,8 % en poids d'une poudre de paille torréfiée.
PCT/KR2016/003473 2015-04-13 2016-04-04 Composition permettant d'augmenter la prise alimentaire et de favoriser la croissance, et son procédé de préparation WO2016167502A1 (fr)

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KR1020150051765A KR101550354B1 (ko) 2015-04-13 2015-04-13 사료섭취 증진 및 성장 촉진제 조성물 및 그 제조방법
KR10-2015-0051765 2015-04-13

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114982870A (zh) * 2022-04-13 2022-09-02 厦门安国腾新材料有限公司 一种提高马科动物消化吸收能力的饲料添加剂及其应用

Families Citing this family (2)

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KR101949481B1 (ko) * 2018-05-04 2019-05-02 (주)케이앤씨바이오 사료섭취 증진제 조성물 및 그 제조방법
KR102236857B1 (ko) * 2018-12-28 2021-04-06 강원대학교산학협력단 시프로헵타딘 유도체, 이의 제조방법 및 이를 포함하는 식욕 촉진용 조성물

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR980000100A (ko) * 1996-06-01 1998-03-30 임영철 양식어류의 성장촉진을 위한 사료 첨가제 조성물
KR100860209B1 (ko) * 2007-07-31 2008-09-24 남궁성조 유황이 함유된 한약재를 이용한 기능성 사료첨가제 및 이를첨가한 사료로 사육, 생산한 돈육
KR20120014336A (ko) * 2010-08-09 2012-02-17 (주)이엘티사이언스 사료 섭취 증진제 조성물 및 그 제조방법
KR20130002292A (ko) * 2011-06-28 2013-01-07 주식회사 비보존 다중 타겟팅의 상승 효과를 유발하는 유효물질의 조합 및 그 용도

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR980000100A (ko) * 1996-06-01 1998-03-30 임영철 양식어류의 성장촉진을 위한 사료 첨가제 조성물
KR100860209B1 (ko) * 2007-07-31 2008-09-24 남궁성조 유황이 함유된 한약재를 이용한 기능성 사료첨가제 및 이를첨가한 사료로 사육, 생산한 돈육
KR20120014336A (ko) * 2010-08-09 2012-02-17 (주)이엘티사이언스 사료 섭취 증진제 조성물 및 그 제조방법
KR20130002292A (ko) * 2011-06-28 2013-01-07 주식회사 비보존 다중 타겟팅의 상승 효과를 유발하는 유효물질의 조합 및 그 용도

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114982870A (zh) * 2022-04-13 2022-09-02 厦门安国腾新材料有限公司 一种提高马科动物消化吸收能力的饲料添加剂及其应用

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