WO2016107568A1

WO2016107568A1 - Insecticidal composition and uses thereof

Info

Publication number: WO2016107568A1
Application number: PCT/CN2015/099649
Authority: WO
Inventors: 罗昌炎; 詹姆斯•T.•布里斯托
Original assignee: 江苏龙灯化学有限公司
Priority date: 2014-12-30
Filing date: 2015-12-30
Publication date: 2016-07-07
Also published as: CN107897202A; CN105794831A; CN105794831B

Abstract

Disclosed are an insecticidal composition and a use thereof, relating to an insecticidal combination containing Bifenthrin and Indoxacarb used as active ingredients. The insecticidal composition is used for preventing or controlling animal pests found in agriculture, animal health, forests, gardens, leisure equipment, storage product protection and the health field. The insecticidal composition contains active ingredients of Bifenthrin and Indoxacarb at a weight ratio of 1:100 to 100:1. The Bifenthrin and Indoxacarb totally occupy 0.5% to 100% of the composition by weight.

Description

Insecticidal composition and use thereof

Technical field

The present invention relates to a pesticidal composition comprising an active ingredient consisting of bifenthrin and indoxacarb. The present invention also relates to the use of bifenthrin and indoxacarb in combination for preventing or controlling pests, and a method of preventing or controlling pests.

Background technique

Chemical control is an important means of preventing or controlling pests in agriculture or public health. However, the currently used agents are still not satisfactory for the effects of certain pests; and, due to the long-term use of insecticides, many pests have developed resistance to commonly used insecticides. It is becoming increasingly difficult to use conventional chemicals for prevention and control. Therefore, there is an urgent need to develop new methods and drugs for controlling these pests. In addition, current environmental and economic requirements for pesticides are increasing, such as spectrum of action, toxicity, selectivity, application rate, pesticide residues, and advantageous formulation capabilities. In addition, the development of new novel drugs that have advantages over at least one or some aspects relative to existing drugs has become an urgent problem to be solved because of the potential for resistance to known active compounds.

Bifenthrin, chemical name: (1R,S)-cis-(Z)-2,2-dimethyl-3-(2-chloro-3,3,3-trifluoro-1 -propenyl)cyclopropanecarboxylic acid-2-methyl-3-phenylbenzyl ester, the structural formula is:

Bifenthrin is a pyrethroid insecticide developed by American Fulfill, which acts to inhibit the conduction of insect axons, and has anti-avoidance, knockdown, contact and stomach toxicity. It has a wide spectrum of insecticides, high activity, rapid drug effect, and is resistant to rain after spraying. It has good control effects on Lepidoptera larvae, Homoptera, Orthoptera, Hemiptera and mites. Suitable for crops such as tea, cotton, fruit trees and vegetables. However, for long-term use, pests are prone to resistance.

Indoxacarb, chemical name: 7-chloro-2,3,4a,5-tetrahydro-2-[methoxycarbonyl(4-trifluoromethoxyphenyl)carbamoyl]indole [1,2-e][1,3,4-]oxadiazine-4a-carboxylic acid methyl ester, the structural formula is:

Indoxacarb is an insecticide developed and produced by DuPont of the United States. It has contact and stomach toxicity and is effective against larvae of all ages. The agent enters the insect body through contact and feeding, and the nerve cell loses its function by blocking the sodium ion channel in the insect nerve cell; the insect stops eating after 0-4 hours, and then the parasite is paralyzed, and the coordination ability of the insect is decreased. Causes the larva to fall from the crop and usually die within 24-60 hours after the drug. Indomethacin has a unique insecticidal mechanism and has no cross-resistance with other insecticides; it is low-toxic to mammals and livestock, and it is safe for beneficial insects such as non-target organisms in the environment, and has low residue in crops. It can be harvested in 2 days, especially for crops that have been harvested many times, such as vegetables and tea. Suitable for the control of tea, apple, pear, peach, apricot, kale, broccoli, kale, tomato, pepper, cucumber, courgette, eggplant, lettuce, cotton, potato, grape and other crops on the green leafy green tea, tea Ruler, leaf moth, codling moth, beet armyworm, diamondback moth, cabbage caterpillar, Spodoptera litura, cabbage moth, cotton bollworm, tobacco budworm, diamond, potato beetle, etc.

The activity of bifenthrin and indoxacarb alone is good; however, they are not always sufficient to meet the high requirements of insecticides, acaricides or nematicides when used at low application rates or for individual pests.

A typical need in the field of pest control is the need to reduce the dose rate of active ingredients. And reduce or avoid adverse environmental or toxicological effects while still allowing effective pest control. Another requirement is the ability to combine knockdown activity and duration of action, ie, combined with rapid action and long-acting action.

Another difficulty with the use of insecticides is that repeated and unique use of a single insecticidal compound in many cases results in a rapid selection of pests that produce natural or adaptive resistance to the active compound. Therefore, there is a need for pest control agents that help prevent or overcome drug resistance.

Summary of the invention

An object of the present invention is to solve the above problems and to provide a pesticidal composition which, by combining bifenthrin and indoxacarb, has a gain effect in controlling effects, and Expanded the insecticidal spectrum, improved the rapid action and long-term effect on pest control, and delayed the emergence of drug resistance.

It is an object of the present invention to provide at least one of the problems addressed, such as reducing the dosage rate, increasing the activity profile, combining knockdown activity and duration of action, and delaying resistance.

Accordingly, it is an object of the present invention to provide a pesticidal composition comprising an active ingredient consisting of bifenthrin and indoxacarb.

The insecticidal composition of the present invention is achieved by the following technical solutions:

A pesticidal composition comprising an active ingredient consisting of bifenthrin and indoxacarb, wherein the weight ratio of bifenthrin to indoxacarb is from 1:100 to 100:1.

An insecticidal composition, the active ingredient consisting of bifenthrin and indoxacarb, wherein the weight ratio of bifenthrin to indoxacarb is 1:50 to 50:1, preferably 1:20 to 20:1, More preferably, it is 1:10 to 10:1.

A pesticidal composition, the active ingredient bifenthrin and indoxacarb, in total, comprises from 0.5% to 100%, preferably from 1% to 80%, more preferably from 5% to 60% by weight of the composition.

An insecticidal composition of the invention further comprises a carrier and/or a surfactant.

The insecticidal composition of the present invention is in the form of a suspension, a microcapsule, an emulsifiable concentrate, a suspending agent, a water-dispersible granule, a wettable powder, a suspoemulsion, an aqueous emulsion, a suspension seed coating agent, a granule, and a bait. .

The present invention also provides a use of the pesticidal composition of the present invention for preventing or controlling agricultural pests.

The present invention also provides a use of the pesticidal composition of the present invention for preventing or controlling agricultural pests that invade plants or plant propagation materials.

The plant propagation material is seedlings, rhizomes, seedlings, cuttings or seeds.

The agricultural pests are cotton bollworm, peach small heartworm, pear small heartworm, hawthorn leafhopper, citrus scutellaria, tea wing scorpion, rapeseed, cabbage caterpillar, diamondback moth, red spider, tea moth, greenhouse whitefly, tea scorpion , tea caterpillar, leafhopper, beet armyworm, cabbage caterpillar, Spodoptera litura, cabbage moth, tobacco budworm, apple moth, diamond, beetle.

In another aspect, the present invention also provides a method of preventing or controlling agricultural pests, which comprises applying the pesticidal composition of the present invention to a target agricultural pest and/or its environment.

A method of protecting a plant against attack by an agricultural pest comprising contacting the pesticidal composition of the present invention with a target useful plant, a target agricultural pest, and/or an environment thereof, a propagation material of the target useful plant.

A method of protecting plants from attack by agricultural pests, comprising separating, sequentially or simultaneously bifenthrin and indoxacarb.

A method of preventing or controlling agricultural pests, wherein bifenthrin and indoxacarb are each in the form of a formulated composition.

A method of protecting a plant seed comprising contacting the seed with an effective amount of the pesticidal composition of the present invention prior to sowing and/or after germination.

The use of the pesticidal composition of the invention for treating seeds.

In another aspect, the invention also provides a pesticidal composition as described for use in preventing or controlling a sanitary pest. The sanitary pests are red fire ants, termites, mosquitoes, and flies.

The present invention also provides a method of preventing or controlling a sanitary pest comprising applying the pesticidal composition of the present invention to a target sanitary pest and/or its environment.

The benefits of the present invention by combining the two are as follows:

A. The synergistic effect on pests is obvious, which can reduce the dosage of the two components;

B. The combination of the two solves the problem of pest persistence period and quick-acting effect, thereby reducing the number of medications and reducing labor costs;

C. Delayed the production of resistance: the mechanism and mode of action of the two are completely different. After combination, they have the effects of contact, stomach poisoning, etc., so that the pests are more easily killed, thereby delaying the generation of resistance;

detailed description

The present inventors have unexpectedly discovered that the combination of bifenthrin and indoxacarb not only provides an increase in the additiveness to the insecticidal spectrum, but more importantly, a surprising synergy can be achieved.

The term "synergistic effect" as used herein means that the insecticidal effect of the active agent combination or composition of the present invention is greater than the sum of the effects of the respective active agents, or that the effect is superadditive. Also, see Tammes The effect defined by the method is "Isoboles, a graphic representation of synergism in pesticides", Netherlands Journal of Plant Pathology, 70 (1964), pages 73-80.

The total amount of the active ingredient compound in the pesticidal composition of the present invention can be selected depending on specific factors such as the dosage form, the subject to be administered, the method of administration, and the like. Bifenthrin and indoxacarb together comprise from 0.5% to 100%, preferably from 1% to 80%, more preferably from 5% to 60% by weight of the composition.

The pesticidal compositions of the present invention may also optionally comprise an agronomically acceptable surfactant and/or extender.

According to the invention, the term "filler" refers to a natural or synthetic organic or inorganic compound which can be combined or combined with an active compound to make it easier to apply to a subject, such as a plant, crop or grass. Therefore, the filler is preferably inert and at least agronomically acceptable. The filler may be a solid or a liquid.

Suitable solid carriers are, for example, pulverized and classified natural rocks such as calcite, marble, pumice, sepiolite, dolomite, and synthetic particles of inorganic and organic powders, as well as organic materials such as paper, sawdust, coconut shell, and corn ears. Axes and granules of tobacco stems;

Suitable liquid carriers are, for example, water, polar and non-polar organic chemical liquids, such as aromatic and non-aromatic hydrocarbons (such as paraffin, alkylbenzene, alkylnaphthalene, chlorobenzene), alcohols and polyols (if appropriate, It may also be substituted, etherified and/or esterified), ketones (such as acetone, cyclohexanone), esters (including fats and oils) and polyethers, unsubstituted and substituted amines, Amides, lactams (such as N-alkylpyrrolidone) and lactones, sulfones and sulfoxides (such as dimethyl sulfoxide).

If the liquid carrier used is water, it is also possible to use, for example, an organic solvent as a co-solvent. Suitable liquid solvents are mainly: aromatic hydrocarbons such as xylene, toluene or alkylnaphthalene; chlorinated aromatic hydrocarbons and chlorinated aliphatic hydrocarbons such as chlorobenzene, vinyl chloride or dichloromethane; aliphatic hydrocarbons such as cyclohexane or paraffin such as petroleum fractions. Mineral and vegetable oils; alcohols such as Butanol or ethylene glycol, and their ethers and esters; ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone; strong polar solvents such as dimethyl sulfoxide.

A surfactant may be used for emulsifying, dispersing, solubilizing, and/or wetting the active ingredient compound, and examples thereof include fatty alcohol polyoxyethylene ether, polyoxyethylene alkyl aryl ether, polyoxyethylene higher fatty acid ester, and poly Phosphate of oxyethylene alcohol or phenol, fatty acid ester of polyhydric alcohol, naphthalenesulfonic acid polymer, lignosulfonate, polymer comb-shaped branched copolymer, butyl naphthalenesulfonate, alkylarylsulfonate Acid salt, sodium alkyl sulfosuccinate, oil and fat, fatty alcohol and ethylene oxide condensate, alkyl taurate polyacrylate, protein hydrolysate. Suitable oligosaccharides or polymers are for example based on the individual ethylene monomers, acrylic acid, polyoxyethylene and/or polyoxypropylene or their combination with, for example, (poly)alcohols or (poly)amines.

For dispersing, stabilizing, and adhering the active ingredient compound, for example, xanthan gum, magnesium aluminum silicate, gelatin, starch, cellulose methyl ether, polyvinyl alcohol, polyvinyl acetate, and natural phospholipids such as cephalin and eggs can be used. Phospholipids) and auxiliary agents such as synthetic phospholipids, bentonite, and sodium lignosulfonate.

Among them, antifreeze can be selected from ethylene glycol, propylene glycol, glycerin, and sorbitol. As the deflocculating agent of the suspension product, an auxiliary agent such as a naphthalenesulfonic acid polymer or a polymeric phosphate can be used. As the antifoaming agent, a silicone antifoaming agent can be used. In order to improve the fluidity of the solid product, an auxiliary agent such as paraffin, stearate or alkyl phosphate may be used.

Colorants which can be used, such as inorganic pigments such as iron oxide, titanium oxide and Prussian blue; and organic pigments/dyes: alizarin dyes, azo dyes and metal phthalocyanine dyes; and trace elements such as iron salts, manganese salts, Boron salts, copper salts, cobalt salts, molybdenum salts and zinc salts.

Optionally, other additional components may also be included, such as protective colloids, binders, thickeners, thixotropic agents, penetrants, stabilizers, masking agents.

The pesticidal composition of the present invention can be used as it is, in the form of a preparation or as a form of use prepared therefrom, such as an aerosol, a suspension, a microcapsule, a fine granule, a flowable concentrate, a ready-to-use solution , powder, emulsifiable concentrate, water emulsion, oil emulsion, large granule, microparticle, oil dispersion powder, oil miscible fluid concentrate, oil mixed solution, foaming agent, paste, suspension concentrate, suspoemulsion, soluble concentrate Soluble powders, granules, water-soluble granules and/or tablets, water-soluble granules, wettable powders, natural or synthetic materials impregnated with active compounds, microcapsules in polymeric materials, and water-dispersible granules.

In a preferred embodiment, the agrochemical composition is an emulsifiable concentrate, a suspending agent, a seed coating, and water. Dispersible granules, wettable powders, suspoemulsions, aerosols, aqueous emulsions, microcapsule suspensions, microcapsule suspension-suspending agents, ultra low volume liquids, baits.

The formulations of the present invention can be prepared by mixing the active compounds with conventional additives in a known manner. The conventional additives such as a conventional extender and a solvent or diluent, an emulsifier, a dispersant, and/or a binder or fixative, a wetting agent, a water repellent, and if necessary, a drier and a colorant , stabilizers, pigments, defoamers, preservatives, thickeners, water and other processing aids.

These compositions include not only immediate application to the subject to be treated by means of suitable equipment such as spray or dusting equipment, but also concentrated commercial compositions which require dilution prior to application to the subject.

The pesticidal composition of the present invention can be formulated into a preparation suitable for administration in the form of a composition of its active ingredient compound, or it can be administered in the form of a combination of a suitable dosage of a commercial preparation. It can also be administered in combination with other active agents such as insecticides, attractants, sterilants, bactericides, acaricides, nematicides, fungicides, growth regulators, herbicides, safes. Agents, fertilizers or chemical pheromones.

The present invention also provides a use of the pesticidal composition of the present invention for preventing or controlling agricultural pests and sanitary pests.

The invention also provides a use of the pesticidal composition of the invention for the prevention or control of sanitary pests.

The pesticidal composition of the invention is suitable for controlling animal pests in the fields of agriculture, horticulture, animal husbandry, forestry, garden and leisure equipment, storage product protection and hygiene, especially insects, arthropods, parasitic worms, nematodes and Mollusk. The pesticidal compositions of the present invention simultaneously exhibit good tolerance to plants, low toxicity to warm-blooded species, and good environmental compatibility. It is active against normally sensitive and resistant varieties and active against all or special developmental stages. The above pests include:

From the Isopoda, such as the Oniscus aselluse, the Armadillidium vulgare, and the Porcellio scaber.

From the foot of the family, such as Blaiuus guttulatus.

From the lip foot, such as the Geophilus carpophagus and Scutigera spp.

From the comprehensive program, such as Scutigerella immaculate.

From the order of the iris, such as Lepisma saccharina.

From the order of the tail, such as the Onychiurus armatus.

From the order of the Orthoptera, such as Acheta domesticus, Gryllotalpa spp., Locusta migratoria migratorioides, Melanoplus spp., and Schistocerca gregaria.

From the order of the eye, such as Blatta orientalis, Periplaneta Americana, Leucophaea maderae, Blattella germanica.

From the order of the constellation, such as the European ball (Forficula auricularia).

From the order of the Isoptera, such as the genus Rhinoceros.

From the order of the eye, such as the Pediculus humanus corporis, the genus Blind, and the long-legged genus, the genus, the genus.

From the order of the Thysanoptera, such as the Hercinothrips femoralis, the Thrips tabaci, the Thrips palmi and the Frankliniella accidentalis.

From the genus Heteroptera, such as the genus Dilister, Dysdercus intermedius, Piesema quadrata, Cimex lectularius, Rhodnius prolixus and Cone .

From the Homoptera, such as Aleurodes brassicae, Bemisia tabaci, Trialeurodes vaporariorum, Aphis gossypii, Brevicoryne brassicae, Camellia Cryptomyzus ribis, Brevicoryne brassicae, Aphispomi, Eriosoma lanigerum, Hyalopterus arundinis, Phylloxera vastatrix, Aphis gossypii, wheat Macrosiphum avenae, genus Phorodo, Phophodo, Nephotettix cincticeps, Lecanium corni, Saissetia oleae, rice planthopper (Laodelphaxstriatellus), brown rice bran (Nilaparvata lugens), Aonidiel1a aurantii, Aspidiotus hederae, Aphis genus and Hibiscus.

From Lepidoptera, such as Pectinophora gossypiella, Bupalus piniarius, Chemimatobia brumata, Lithoclletis blancardela, Hyponomeuta padella, Plutella xylostella, Canopy caterpillar (Malacosoma neustria), Euproctis chrysorrhoea, genus, genus Bucculatrix thurberiella, Phyllocnis tiscitrella, genus, genus, genus, genus, diamond (Eariasinsulana), Noctuidae, Mamestra brassicae, Panolis flammea, Noctuidae, Trichoplusiani, Carpocapsa pomonella, Verticillium, Brassica (Pyraustlla), Tineola bisselliella, Tinea Pellionella, Hofmannophila pseudospretella, Cacoecia podana, Choristoneura fumiferana, grape locust moth Clysia ambiguella), Homona magnanima, Tortrix viridana, genus, genus Insects (Oulema oryzae).

From Coleoptera, such as Anobium punctatum, Rhizopertha dominica, Bruchidius obtectus, Acanthoscelides obtectus, Hylotrupes bajulus, Agelastica alni, potato beetle (Leptinotarsadecemlineata), Phaedon cochleariae, Psylliodes chrysocephala, Epi1achna varivestis, Oryzaephilus surinamensis, Genus, genus, Otiorrhynchus sulcatus, Cosmopolites sordidus, Ceuthorrhynchusassimilis, Hypera postica, genus, genus , Round genus, ranunculus, white genus, genus Meligethes aeneus, genus, Niptus hololeucus, Gibbiumpsylloides, genus, yellow powder (Tenebrio molitor), genus, genus, genus Melonontha melolontha, juvenile chameleon (Amphimallon solstitialis), brown xinxi Costelytra zealandica and Lisorhoptrus oryzophilus.

From Hymenoptera, such as the genus Hymenoptera, the genus Hymenoptera, the genus of the genus, the genus of the family (Monomorium pharaonis) and the genus.

From Diptera, such as Aedes, Anopheles, Culex, Drosophila melanogaster, Musca domestica, Drosophila, Calliphoraerythrocephala, Mercera, and Golden flies Genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus Pythium, Pegomyiahyoscyami, Ceratitis capitata, Dacusoleae and Tipula paludosa, Musca, and Liriomyza.

From the order of the eye, such as the oriental squid (Xenopsylla cheopis) and the horned squirrel.

From arachnids, such as Scorpio maurus, Latrodectus mactans, Acarus siro, genus, genus, Dermanyssys gallinae, tea deer ( Eriophyesribis), Phyllocoptruta oleivora, burdock, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus, genus螨 (Bryobia praetiosa), red spider genus, red leaf genus, genus, genus.

Parasitic plant nematodes include, for example, the genus Tetrarid, the genus Radopholus similis, Ditylenchus dipsaci, Tylenchulus semipenetrans, the genus Heterodera, the genus Heterodera, the root-knot nematode Genus, Nematodes, Nematodes, Spirulina, and Trichinella, Burmese.

The pesticidal compositions of the present invention are particularly useful for controlling "bite" pests, which specifically include the following pests:

From Lepidoptera, such as Pectinophora gossypiella, Bupalus piniarius, Cheimatobia brumata, Lithocolletis blancardel1a, Hyponomeuta padella, Plutella xylostella, Canopy caterpillar (Malacosoma neustria), Euproctis chrysorrhoea, genus Moth, cotton leaf perforated moth (Bucculatrix thurberlella), orange leaf miner (Phyllocnistiscitrella), genus, genus, genus, genus, genus, all Drill (Eariasinsulana), Noctuidae, Mamestra brassicae, Panolisflammea, Noctuidae, Trichoplusiani, Carpocapsa pomonella, Verticillium, Amaranthus, Pyrausta nubilalis, Ephestia kuehniella, Gal1eriamellonella, Tineola Bisselliella), Tineapellionella, Hofmannophila pseudospretella, Cacoecia podana, Capua reticulana, Choristoneura fumiferana, Clysia ambiguella, ochre leaf moth (Homona magnanima), Tortrix viridana, genus, Oulema oryzae.

From Coleoptera, such as Anobium punctatum, Rhizopertha dominica, Bruchidius obtectus, Acanthoscelides obtectus, Hylotrupes bajulus, Agelastica alni, potato beetle (Leptinotarsa decemlineata), Phaedon cochleariae, Psylliodes chrysocephala, Epilachnavarivestis, Oryzaephilus surinamensis, When the genus is genus, the genus Mito, the genus Otiorrhynchus sulcatus, the genus Cosmopolites sordidus, the genus Ceuthorrhynchus assimilis, the Hypera postica, the genus, the skin Genus, genus, genus, genus, genus, genus Meligethes aeneus, genus Niptus, genus Gibbium psylloides, genus , Tenebrio molitor, genus, golden genus, Melonontha melolontha, Amphimallon solstitialis, New Zealand wing rib beetle, chafer angle (Costelytra zealandica) and rice water weevil (Lissorhoptrus oryzophilus).

The insecticidal composition containing bifenthrin and indoxacarb of the present invention is particularly suitable for controlling "sucking" pests, and the pests specifically include the following pests:

From the order of the Homoptera, such as Aleurodes brassicae, Bemisia tabaci, Trialeurodes vaporariorum, Aphis gossypii, Brevicoryne brassicae, Camel sinus (Cryptomyzus ribis), Aphis fabae, Aphispomi, Eriosoma lanigerum, Hyalopterusarundinis, Phylloxera vastatrix, Aphis gossypii, Mai long tube Mac (Macrosiphum avenae), genus Phenodonhumuli, Rhopalosiphum padi, Cicadellidae, Nephotettix cincticeps, Lecanium corni ), Saissetia oleae, Laodel phaxstriatellus, Nilaparvata lugens, Aonidiella Aurantii), Aspidiotus hederae, Aphis genus and Hibiscus.

Preferably, the pesticidal composition of the present invention is suitable for controlling cotton bollworm, peach heartworm, pear small heartworm, hawthorn spider mites, citrus cantharidin, tea wing mites, rapeseed meal, cabbage caterpillar, diamondback moth, red spider, tea fine Moth, greenhouse whitefly, tea mites, tea caterpillar, spider mites, beet armyworm, cabbage caterpillar, Spodoptera litura, cabbage moth, tobacco budworm, apple moth, diamond, beetle and other agricultural pests.

Preferably, the pesticidal composition of the present invention is suitable for controlling sanitary insects such as termites, red fire ants, mosquitoes, and flies.

In another aspect, the present invention also provides a method of preventing or controlling agricultural pests, sanitary pests, and the insecticidal composition of the present invention is applied to target agricultural pests, sanitary pests and/or their environment.

The present invention also provides a method of protecting plants against attack by agricultural pests and sanitary pests, comprising contacting the pesticidal composition of the present invention with a target useful plant, a target pest, and/or an environment thereof, a propagation material of the target useful plant.

The meaning of the plants herein is to be understood as meaning all plants and plant populations. Plants are plants obtainable by conventional breeding and preferred methods or by biotechnological and genetic engineering methods or by a combination of these methods. The plants include transgenic plants, as well as plant varieties that are protected or unprotected by plant breeders' rights.

Useful plants which can be used in the protection of the present invention, as well as the application of the pesticidal composition according to the invention, include: cereal plants such as wheat, oats, barley, triticale and rye, as well as corn, sorghum and chestnut, rice; beets, such as sugar Beet or fodder beet; fruit, such as apple fruit, stone fruit, tree nut or soft fruit such as apple, pear, plum, peach, banana, almond, walnut, pistachio, cherry or berry, such as strawberry, or blackberry; Crops such as kidney beans, peas or soybeans; oil crops such as canola, mustard, olive, sunflower, ramie, cocoa or peanut; cucurbits such as pumpkin, zucchini, cucumber or melon; fiber plants such as cotton, flax, marijuana Or jute; citrus fruits such as oranges, lemons, grapefruits or oranges; vegetables such as spinach, lettuce, asparagus, cabbage, carrots, onions, tomatoes, red peppers, potatoes or bell pepper; medlars such as avocado, cinnamon or Camphor; and tobacco, nuts, coffee, eggplant, sugar cane, tea tree, pepper, vine, hops, plantain, gum plant, grass , Lawn, forage grasses, as well as ornamental plants, such as petunia, pansies and impatiens; and shrubs, broad-leaved trees and evergreens, such as conifers.

The treatment of plants with the pesticidal compositions of the invention is carried out directly by conventional treatment or by acting on their environment, habitat or storage area, such as impregnation, Watering, spraying, misting, spreading, dusting, fogging, spreading, foaming, coating, coating, drip irrigation, etc. can be applied to the leaves of plants (foliar application), and the frequency and amount of application can be adjusted to Adapt to the extent of the agricultural pests.

The pesticidal compositions of the present invention are also suitable for protecting plant propagation material such as seeds, fruits, tubers or nucleoli or plant cuttings from pests, particularly insects and mites. The propagation material can be treated with the composition prior to application, such as seed dressing prior to sowing. The active ingredient can also be applied to the seed (coating) by soaking the nucleoli in the liquid composition or coating the nucleolus with a solid composition. The composition can also be applied to the application site when the propagation material is applied, for example, within the seed ditch during sowing. These methods of treating plant propagation materials and plant propagation materials so treated are further subject matter of the present invention.

The term "plant propagation material" is understood to mean all parts of the plant capable of reproduction, such as seeds, as well as plant material such as cuttings or tubers (for example potatoes). Thus, the plant parts used herein include plant propagation material. Mention may be made, for example, of seeds (in the narrow sense), roots, fruits, tubers, bulbs, rhizomes and plant parts. Germinated plants and effective plants to be inhibited after germination from the soil or after emergence are also mentioned. Young plants can be protected by whole or partial treatment by dipping prior to transplantation.

Plant parts and subsequently grown plant organs are any part of a plant produced by plant propagation material such as seeds. Plant parts, plant organs and plants can also benefit from protecting plants from plant diseases by applying the compositions to plant propagation materials. Certain plant parts and certain subsequently grown plant organs can also be considered as plant propagation material, which can itself be applied (or treated) with the composition; thus plants produced from treated plant parts and treated plant organs, Other plant parts and other plant parts may also benefit from protecting the plant from plant pests by applying the composition to certain plant parts and certain plant organs.

For the treatment of plant propagation material, in particular seeds, the active ingredient can also be applied to the seed by successively impregnating the tubers or grains with a liquid preparation of the respective active ingredients, or by coating with a combined wet or dry preparation (coating) ).

The pesticidal composition of the present invention is applied to the seed in itself or in a suitable dosage form. Preferably, the seed is treated in a steady state such that the treatment does not cause any damage. The treatment of the seed can usually be carried out at any time between harvesting and sowing. Usually must be noted during seed treatment, applied to the species The amount of the composition of the invention and/or the amount of other additives is selected so as not to affect the germination of the seed or to damage the resulting plant.

A method of protecting a seed comprising contacting the seed with a synergistically effective amount of a pesticidal composition of the present invention prior to sowing and/or after germination.

The invention further relates to a seed treated with the pesticidal composition of the invention.

The pesticidal compositions of the present invention can be applied to the environment, habitat or storage area in which the plants are grown. The environment and habitat of plant growth refer to a support capable of rooting and growing crops, such as soil, water, etc. Specific raw materials can be used, for example, sand, pumice, vermiculite, diatomaceous earth, agar, gelatin, High molecular substances, asbestos, wood chips, bark, etc. Soil is preferred.

A method of applying a medicament to the soil, for example, diluting the liquid medicament in water or undiluting the root applied directly to the root of the plant or the method of growing the farm, and spreading the granule into the root of the plant or in the field of the nursery Before spraying, powder, water-dispersible granules, etc. are sprayed into the soil and mixed with the soil as a whole. Before the planting or planting the object, the powder and the water-dispersible granules are diluted and sprayed in the planting hole and the seeding ditch. The method of sowing, etc.

The methods of the invention also provide for the combined administration of the active compound in separate, sequential or simultaneous manner. It is common and advantageous to administer the compositions or combinations of active agents of the invention in the following dosages:

- for foliar treatment: 0.1-10000 g/ha, preferably 5-1000 g/ha, more preferably 10-50 g/ha; for dipping or drip application, the dose may even be reduced, especially when an inert matrix is applied Such as asbestos or perlite;

- for seed treatment: 2-200 g / 100 kg seed, preferably 3-150 g / 100 kg seed;

- For soil treatment: 0.1-10000 g/ha, preferably 1-5000 g/ha.

The above dosages are merely exemplary exemplary dosages, and the dosage rate will be adjusted by those skilled in the art according to the actual conditions and needs, especially depending on the nature of the plants or crops to be treated and the pest conditions.

On the other hand, the treatment of the present invention may also produce a super-additive effect of improving plant growth, increasing tolerance to high or low temperatures, increasing tolerance to drought or salinity to water or soil, and increasing flowering. Quality, ease of harvesting, accelerated maturity, improved harvesting yield, improved quality of harvested products and/or improved nutritional value, improved storage stability of harvested products and/or their processing properties.

Furthermore, it has been found that the pesticidal compositions of the present invention have an effective insecticidal action against pests that destroy industrial materials.

As an example and preferably the following insects are proposed, but are not limited thereto:

Coleoptera, such as Hyloptrupes bajulus, Chlorophorus pilosis, furniture stolen, and smashed (Xestobiumrufovillosu, Ptilinus pecticornis, Dendrobium pertinex, pine buds Ernobius mol1is, Priobiumcarpini, Lyctus brunneus, Lyctus africanus, Lyctus planicollis, Lyctus linearis, whitefly (Lyctus pubescens) ), Trogoxylon aequale, Minthesrugicollis, genus genus, genus Apo temonachus, Bostrychus capucins, Heterobostrychusbrunneus, Spinosaurus genus, Dinoderus minutus.

Genus, such as Sirex juvencus, Urocerusgigas, Urocerus gigas taignus, and Urocerus augur.

Termites, such as Kalofermes flavicollis, Cryptotermes brevis, Heterotermes indicola, Reticulitermes flavipes, Reticulitermes santonensis, Reticuli Termeslucifugus), Mastotermes darwiniensis, Zootermopsis nevadensis, Coptotermesformosanus.

Iris, such as Taiwanese fish (Lepisma saccharina).

Industrial materials herein are understood to mean inanimate materials such as preferred polymers, binders, glues, paper and board, leather, wood, wood products and coatings. Materials which are intended to protect them from insect attack are particularly preferably wood and wood processed articles.

Wood and wood-processed articles which may be protected by the pesticidal compositions of the invention or mixtures containing the compositions are understood to mean, for example:

Construction timber, wooden beams, railway sleepers, bridge components, breakwaters, wooden vehicles, boxes, pallets, containers, telephone poles, wooden partitions, wooden windows and doors, plywood, flower panels, joinery, or Wood products commonly used in building construction or building joinery.

The pesticidal composition can be used as it is, in a concentrate or a conventional preparation such as a powder, a granule, a solution, a suspension, Used in the form of an emulsion or paste.

The abovementioned preparations can be prepared in a manner known per se, for example by stabilizing the active compound with at least one solvent or diluent, emulsifier, dispersant and/or binder or fixative, water repellent, desiccant if required and UV The agent is mixed with colorants and pigments as needed, as well as other processing aids.

The pesticidal compositions or concentrates for the protection of wood and wood products contain the active compound of the invention in a concentration of from 0.0001 to 95% by weight, in particular from 0.01 to 60% by weight.

The amount of the composition or concentrate depends on the species and amount of the insect and the medium. The optimum amount in each case can be determined by a series of application tests, but it is usually sufficient to use from 0.0001 to 20% by weight, preferably from 0.001 to 10% by weight, based on the material to be protected.

The pesticidal compositions of the present invention are also suitable for use in the control of enclosed animal pests, particularly insects, spiders and mites, such as dwellings, factory floors, offices, cabins and the like. They can be used in household insecticidal products to control these pests, which are active against sensitive and resistant varieties and for all stages of development. These pests include:

Attention, such as Buthus occitanus.

Attention, such as Persian sharp rim, sharp edge rim, moss, chicken skin hedgehog, home sweet potato, African blunt rim, blood red scallop, cricket (Trombicula alfreddugesi), Neutrombicula autumnalis, house Dust mites, dust mites.

Arachnid, such as the genus Arachnida, Arachnida.

Blind spiders, such as Pseudoscorpiones chelifer, Pseudoscorpiones cheiridium, Opiliones phalangium.

Isoping, such as tide worms, rat women.

Double-footed, such as zebra land, mountain locust.

Lips and feet, such as the genus Mantle.

Zygentoma, such as the genus Codfish, Taiwanese fish, Lepismodes inquilinus.

Attention, such as Oriental lynx, German cockroach, Blattel1a asahinai, Madeira, Astragalus, Hibiscus, Australian cockroach, American cockroach, brown spotted cockroach, black Big chest, long beard.

Jumping sub-heads, such as a family.

Genus, such as the European ball.

Isoptera, such as the wood termite genus, the termite genus.

Insects, such as Lepinatus, Pseudomonas.

Coleoptera, such as the genus of the genus Corydalis, the genus of the genus, the genus of the genus, the genus of the genus, the long-headed glutinous rice, the genus of the genus Corydalis, the genus Arachnid, the glutinous rice, the valley, the rice, the corn,

Diptera, such as Aedes aegypti, Aedes albopictus, Aedes taeniorhynchus, Anopheles, Red-headed fly, High-flying fly, Culex pipiens, Sharp-sounding grave, Culex tarsalis, Drosophila, Summer fly, Housefly, Bailing, Sarcophaga carnaria, genus, cockroach, and cockroach (Tipula paludosa).

Lepidoptera, such as small wax mites, wax mites, Indian ancient spotted owls, valley moths, bagged moths, snail moths.

Attention, such as the scorpion scorpion, the cat scorpion singularly named subspecies, human cockroaches, wearing leather snorkeling, printing mouse scorpion.

Hymenoptera, such as the broad-backed ant, bright-haired ant, black-haired ant, Lasius umbratus, small family ant, Paravespula genus, paving ant.

Eyes, such as head lice, body lice, haze.

Heteroptera, such as tropical bedbugs, temperate bed bugs, and long red hunting crickets, invade the vertebrate.

The pesticidal composition of the present invention can be used as an aerosol, a pressureless spray product such as a pump spray and atomizer spray, an automatic fog forming system, a smoke generator, a foam, a gel, a vaporized sheet made of cellulose or a polymer. Evaporator products, liquid evaporators, gel and membrane evaporators, propeller-driven evaporators, non-energy or passive evaporation systems, worm-catching paper, moth-bags and insecticides, as a puller or powder In the bait for spraying or at the bait position.

Formulation example

Example 1: 2% bifenthrin + 10% indoxacarb suspension

The components such as the active component, the dispersing agent, the wetting agent and the water are uniformly mixed according to the formulation ratio, and after grinding and/or high-speed shearing, 2% bifenthrin + 10% indoxacarb suspension is obtained.

Example 2 20% bifenthrin + 4% indoxacarb WP

The active ingredients, various auxiliaries and fillers are mixed according to the proportions of the formulation, and after being pulverized by an ultrafine pulverizer, 20% bifenthrin + 4% indoxacarb WP can be obtained.

Example 3 0.2% bifenthrin + 20% indoxacarb emulsion

Adding the original drug, solvent and emulsifier together to dissolve into a uniform oil phase; mixing the water-soluble component with water to prepare an aqueous phase; mixing the oil phase with the water phase under high-speed stirring to obtain 0.2% Permethrin + 20% aphid water emulsion.

Example 4 3.5% bifenthrin + 1.5% aphid water dispersible granules

The active ingredient, the dispersing agent, the wetting agent, the disintegrating agent and the filler are uniformly mixed according to the formulation ratio, and are pulverized into a wettable powder by a jet stream, and then a certain amount of water is added to mix and extrude the material. After drying and sieving, 3.5% bifenthrin + 1.5% aphid water dispersible granules were obtained.

Example 5 20% bifenthrin + 0.2% indoxacarb suspension

The components such as active ingredient, dispersing agent, wetting agent and water are uniformly mixed according to the formulation ratio, and after grinding and/or high-speed shearing, 20% bifenthrin + 0.2% indoxacarb suspension is obtained.

Example 6 7.5% bifenthrin + 2.5% indoxacarb suspension

The components such as active ingredient, dispersing agent, wetting agent and water are uniformly mixed according to the formulation ratio, and after grinding and/or high-speed shearing, 7.5% bifenthrin + 2.5% indoxasu suspension is obtained.

Example 7 1% bifenthrin + 10% indoxacarb WP

The above components are mixed in proportion, ground and pulverized to prepare a wettable powder.

Example 8 50% bifenthrin + 1% indoxacarb suspension

The above components are uniformly mixed in proportion and sanded to prepare a suspension.

Example 9 30% bifenthrin + 20% indoxacarb emulsion

Oil phase:

water box:

Bifenthrin and indoxacarb are dissolved in methyl oleate, polystyrene is added to obtain an oil phase; the components in the formulation are uniformly mixed to obtain an aqueous phase; and the oil phase is added to the aqueous phase with stirring to obtain an aqueous emulsion.

Example 10 20% bifenthrin + 1% indoxacarb WP

Example 11 1% bifenthrin + 20% indoxacarb coated granules

The milled active ingredient is uniformly applied to the carrier wetted with polyethylene glycol in a mixer. In this way, dust-free coated granules can be obtained.

Example 12 60% bifenthrin + 20% indoxacarb WP

Example 13 20% bifenthrin + 40% indoxacarb extruded granules

The active ingredient is mixed with the auxiliaries and ground and the mixture is wetted with water. The mixture was extruded and then dried in a stream of air.

Example 14 1% bifenthrin + 50% indoxacarb suspension

Example 15 10% bifenthrin + 20% indoxacarb microcapsule suspension-suspending agent

The oil PAPI, indoxacarb and oil phase formed acetate aqueous solution was added in ATLOX ^TM 4913, to form an emulsion. The catalyst was then heated and kept warm at 50 ° C for 2 hours. After cooling, a microcapsule of indoxacarb was obtained.

ATLOX ^TM 4913, LFH dispersants, antifoaming agents, urea, bifenthrin and water was mixed uniformly, and sanded to prepare a suspension.

The obtained microcapsule of indoxacarb was added to the aqueous suspension of bifenthrin, and uniformly stirred to obtain 10% bifenthrin + 20% indoxacarb microcapsule suspension suspending agent.

Example 16 5% bifenthrin + 15% indoxacarb suspension emulsion

Dissolving bifenthrin in SOLVESSO ^TM 200, adding ethoxylated castor oil to obtain a bifenthrin emulsifiable concentrate; and indoxacarb, a fatty alcohol polyoxyethylene ether sulfosuccinate monosodium disodium, each of the above The components are uniformly mixed in proportion and sanded to prepare a suspension.

The oil phase containing bifenthrin is added to a suspension containing indoxacarb to obtain a suspoemulsion.

Example 17 10% bifenthrin + 10% indoxacarb EC

The above components were mixed and stirred until a transparent homogeneous phase was obtained.

Example 18 1% bifenthrin + 0.01% indoxacarb bait

The above components are uniformly mixed, and then pulverized into a wettable powder by a jet stream, and then a certain amount of water is mixed and extruded to obtain a bait pellet.

Example 19 0.05% bifenthrin + 0.05% indoxacarb bait

Example 20 5% bifenthrin + 5% indoxacarb suspension seed coating agent

The above components were uniformly mixed in proportion and sanded to prepare a suspension seed coating agent.

Example 21 50% bifenthrin + 50% indoxacarb

Bifenthrin 50%

Indoxacarb 50%

Mix bifenthrin and indoxacarb in proportions.

Biological test case

Good insecticidal and acaricidal effects of an insecticidal composition of the invention can be found in the following examples. Although the individual active compounds show disadvantages in their action, the compositions show a simple additive effect over each effect. Synergistic insecticidal and acaricidal effects are present when the effect of the active compound composition exceeds the sum of the effects when the individual active compounds are applied separately. The expected effect of a particular combination of the two active compounds can be calculated using the so-called "Colby Formula" (see S. R. Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations", Weeds 1967, 15, 20-22) as follows:

X is the kill rate when active compound A is used in an amount of mg/ha or at a concentration of mppm, expressed as a percentage of the untreated control,

Y is the kill rate when active compound B is used in an amount of ng/ha or at a concentration of nppm, expressed as a percentage of the untreated control,

E is the kill rate when active ingredients A and B are used in amounts of m and ng/ha or at concentrations of m and n ppm, expressed as a percentage of the untreated control,

Then

If the actual insecticidal lethality exceeds the calculated value, the lethal effect of the composition is superadditive, i.e., there is a synergistic effect. In this case, the actually observed kill rate must exceed the value of the expected kill rate value (E) calculated using the above formula.

Test example 1

Tea green leafhopper test

Solvent 7 parts by weight of dimethylformamide

Emulsifier 2 parts by weight of alkylaryl polyglycol ether

To make a suitable formulation of the active compound, 1 part by weight of active compound is mixed with the amount of solvent and emulsifier, and the concentrate is diluted with water to the desired concentration.

Tea leaves severely infected by tea green leaf mites are impregnated into the active compound preparation of the desired concentration

deal with.

After a desired period of time, the % mortality was determined. 100% means that all tea green leafhoppers have been killed; 0% means that no tea green leafhopper has been killed. The measured mortality rate was calculated using the "Colby Formula".

It has been shown in this test that the pesticidal compositions of the invention exhibit synergistic activity, for example, compared to the active compound alone.

Table 1

Found *= found activity

Calculated *=Applicable to the activity calculated by the Colby formula

Test example 2

Helicoverpa armigera test

Solvent 7 parts by weight of dimethylformamide

Emulsifier 2 parts by weight of alkylaryl polyglycol ether

Cotton leaves severely infected with cotton bollworm are treated by dipping them into a preparation of the active compound of the desired concentration. After a desired period of time, the % mortality was determined. 100% means that all cotton bollworms have been killed; 0% means that no cotton bollworm has been killed. The measured mortality rate was calculated using the "Colby Formula".

Table 2

Found *= found activity

Calculated *=Applicable to the activity calculated by the Colby formula

Test Example 3

Red spider test

Solvent 7 parts by weight of dimethylformamide

Emulsifier 2 parts by weight of alkylaryl polyglycol ether

Citrus leaves severely infected by spider mites are treated by dipping them into the active compound preparation of the desired concentration.

After a desired period of time, the % mortality was determined. 100% means that all red spiders have been killed; 0% means that no red spiders have been killed. The measured mortality was calculated using the "Colby Formula".

table 3

Found *= found activity

Calculated *=Applicable to the activity calculated by the Colby formula

Test Example 4

Whitefly test

Solvent 7 parts by weight of dimethylformamide

Emulsifier 2 parts by weight of alkylaryl polyglycol ether

Tomato leaves severely infected with white meal are impregnated into the active compound preparation of the desired concentration for treatment.

After a desired period of time, the % mortality was determined. 100% means that all white meal has been killed; 0% means that no white meal is killed. The measured mortality was calculated using the "Colby Formula".

Table 4

Found *= found activity

Calculated *=Applicable to the activity calculated by the Colby formula

Test Example 5

Plutella xylostella test

Solvent 7 parts by weight of dimethylformamide

Emulsifier 2 parts by weight of alkylaryl polyglycol ether

Cabbage leaves severely infected by Plutella xylostella are treated by dipping them into the active compound preparation of the desired concentration.

After a desired period of time, the % mortality was determined. 100% means that all Plutella xylostella has been killed; 0% means no The diamondback moth was killed. The measured mortality was calculated using the "Colby Formula".

table 5

Found *= found activity

Calculated *=Applicable to the activity calculated by the Colby formula

Test Example 6

Fly test

Solvent 7 parts by weight of dimethylformamide

Emulsifier 2 parts by weight of alkylaryl polyglycol ether

Place a certain amount of flies in each enclosed space. It is treated with the active compound of the desired concentration.

After a desired period of time, the % mortality was determined. 100% means that all flies have been killed; 0% means that no flies have been killed. The measured mortality was calculated using the "Colby Formula".

Table 6

Found *= found activity

Calculated *=Applicable to the activity calculated by the Colby formula

Test Example 7

Termite test

Solvent 7 parts by weight of dimethylformamide

Emulsifier 2 parts by weight of alkylaryl polyglycol ether

The wood severely eroded by termites is impregnated into the active compound preparation of the desired concentration for treatment.

After a desired period of time, the % mortality was determined. 100% means that all termites have been killed; 0% means that no termites have been killed. The measured mortality was calculated using the "Colby Formula".

Table 7

Found *= found activity

Calculated *=Applicable to the activity calculated by the Colby formula.

Claims

An insecticidal composition characterized in that the active ingredient consists of bifenthrin and indoxacarb, wherein the weight ratio of bifenthrin to indoxacarb is from 1:100 to 100:1.
The insecticidal composition according to claim 1, wherein the weight ratio of the bifenthrin to indoxacarb is from 1:50 to 50:1.
A pesticidal composition according to claim 1, wherein the weight ratio of the bifenthrin to indoxacarb is from 1:20 to 20:1.
The insecticidal composition according to claim 1, wherein the weight ratio of the bifenthrin to indoxacarb is from 1:10 to 10:1.
A pesticidal composition according to claim 1, wherein the weight ratio of the bifenthrin to indoxacarb is from 1:5 to 5:1.
A pesticidal composition according to claim 1 wherein said bifenthrin and indoxacarb comprise from 0.5% to 100% by weight of said composition.
A pesticidal composition according to claim 1 wherein said bifenthrin and indoxacarb comprise a total of from 1% to 80% by weight of said composition.
A pesticidal composition according to claim 1 wherein said bifenthrin and indoxacarb comprise a total of from 5% to 60% by weight of said composition.
A pesticidal composition according to claim 1 further comprising a carrier and/or a surfactant.
The insecticidal composition according to claim 1, wherein the dosage form is: a suspending agent, a microcapsule, an emulsifiable concentrate, a suspending agent, a water-dispersible granule, a wettable powder, a suspoemulsion, an aqueous emulsion, and a suspension species. Clothes, granules, baits.
Use of the pesticidal composition of claim 1 for preventing or controlling agricultural pests.
Use of the pesticidal composition of claim 1 for preventing or controlling agricultural pests that invade plants or plant propagation materials.
The use according to claim 11, wherein the agricultural pest is a cotton bollworm, a peach heartworm, a pear heartworm, a hawthorn leafhopper, a mandarin, a tea hawksbill, a vegetable bud, a cabbage caterpillar, a diamondback moth, a red spider, a tea moth. , whitefly mites, tea mites, tea caterpillars, spider mites, beet armyworm, cabbage caterpillar, Spodoptera litura, cabbage moth, tobacco budworm, apple moth, diamond, beetle.
The use of the plant propagation material according to claim 12, which is seedlings, rhizomes, seedlings, cuttings or seeds.
A method for preventing or controlling agricultural pests, which comprises applying the pesticidal composition of claim 1 to a target agricultural pest and/or its environment.
A method of protecting a plant against attack by an agricultural pest, the insecticidal composition of claim 1 being contacted with a target useful plant, a target agricultural pest, and/or an environment thereof, a propagation material of the target useful plant.
A method of protecting a plant seed comprising contacting the seed with the pesticidal composition of claim 1 prior to sowing and/or after germination.
Use of the pesticidal composition of claim 1 for preventing or controlling a sanitary pest.
A method of preventing or controlling a sanitary pest, which comprises applying the pesticidal composition of claim 1 to a target sanitary pest and/or its environment.