WO2016046208A1

WO2016046208A1 - Tobacco substitute, use and method for production thereof

Info

Publication number: WO2016046208A1
Application number: PCT/EP2015/071751
Authority: WO
Inventors: Gideon Rath; Marek Lachmann; Rainer Schnee; Florian Stukenborg; Yu Lu
Original assignee: Chemische Fabrik Budenheim Kg
Priority date: 2014-09-23
Filing date: 2015-09-22
Publication date: 2016-03-31
Also published as: EP3197299A1; DE102014113776A1; US20170295840A1

Abstract

The invention relates to a tobacco substitute, in particular for use in a water pipe (hookah), pipe or electronic cigarette, which comprises a liquid fluid and a carrier material for said fluid. In order to make a tobacco substitute available which, compared to known tobacco substitute systems, forms denser vapor or denser aerosol, the carrier material of the tobacco substitute according to the invention comprises apatite.

Description

Tobacco substitute, use and method of manufacture

Background of the invention

The present invention relates to a tobacco substitute, the use thereof and a process for its preparation.

In addition to the "real" tobacco commonly used in tobacco products of all kinds, alternative tobacco replacement systems have also been known for some time, with the aid of which flavorings and / or active substances in the form of aerosols, i. Smoke or steam can be consumed. These include, among other things, nicotine-free herbs, but also other particular mineral carrier materials, such as steam stones, which with aromatized fluid, eg. B. Aromasirup or so-called molasses or molasses, are occupied. These carrier materials are portionable and capable of bringing the flavored liquid into an inhalable presentation form. Such carrier materials are used, inter alia, in water pipes (shishas), conventional tobacco pipes and electric cigarettes, so-called e-cigarettes.

If these tobacco substitute systems are heated to a temperature at which neither the carrier material nor the aromatized fluid burns, there is no smoke, as in the case of real tobacco, but a vapor or aerosol, i. finely distributed liquid droplets. Such systems have the advantage that they usually contain no nicotine and no tar, so they are considered less harmful than tobacco. Different tobacco substitution systems are known. WO 201 1/120518 discloses as carrier material a pore-containing rock which contains at least 65% clinoptilolite and is loaded with a fluid which forms an aerosol in the hookah.

DE 10 2007 033 083 discloses a tobacco substitute which has as carrier materials inter alia fiber materials, foams and bulk materials such as montmorillonite, dolomite or kieselguhr. It has been shown that in many of these systems already visibly noticeable thinner smoke or vapor is formed as in real tobacco, which is compared to the classic consumption of real tobacco causes a significantly different smoking sensation. Description of the invention

Against this background, there has been a need for a tobacco substitute system that forms a denser vapor or denser aerosol compared to known systems. This object is achieved by a tobacco substitute, in particular for use in a water pipe (hookah), tobacco pipe or electric cigarette, which comprises a liquid fluid and a carrier material for the fluid, characterized in that the carrier material comprises apatite. It has been found that with such a system a considerable amount of a fluid can be adsorbed or absorbed. It is believed that based on this, a smoking experience comparable to the classic consumption of tobacco can be provided over a longer period of time. In addition, it has been shown that apatite is suitable for the absorption of a wide variety of fluids.

Another advantage of the use of apatite as a carrier material or component of the carrier material is that it remains unchanged under temperatures commonly used in smoking applications in the range of 100 to 350 ° C and thus does not change into the formed aerosol or the vapor formed. For this reason, there is also the possibility of recharging apatite as a carrier material after use with fluid, so that the carrier material is reusable.

The term "fluid" or "liquid fluid" or "substantially liquid fluid" in the sense of this invention refers to fluids which are present in the liquid state at room temperature (18 ° C.) and atmospheric pressure (1, 01325 bar).

In certain embodiments, the fluid comprises water, one or more polyols, one or more sugars, one or more dyes, one or more flavoring agents and / or agents. Examples of suitable polyols according to the invention include but are not limited to glycerine, propylene glycol and mixtures thereof. As sugar, glucose may be used in certain embodiments. In a preferred embodiment, the fluid comprises one or more active substances and / or flavorings. Such agents and flavorants include extracted and / or synthetic plant ingredients, including those of Fruits, herbs, fruit products and plant products and mixtures thereof, for example caffeine and nicotine. Active ingredients and flavorings may be in the form of, for example, esters, ethers, oils, monohydric alcohols or mixtures thereof. Useful and suitable fluids according to the invention are also commercially available for use with steam stones and are also referred to as flavored syrups, molasses or molasses.

As used herein, the term "aerosol" refers to solid and / or liquid particles finely distributed in a gas, and if it is solely a liquid particle, the aerosol is also called a vapor, and is essentially a solid particle , the aerosol is also called smoke.

As used herein, the term "apatite" refers to calcium phosphates such as hydroxylapatite (Ca ₅ (PO ₄ ) 30H), fluoroapatite (Ca ₅ (PO ₄ ) ₃ F), chloroapatite (Ca ₅ (PO ₄ ) ₃ CI), carbonate-containing apatites and other naturally occurring and / or synthetically produced apatites In a particularly preferred embodiment of the invention, the apatite is hydroxyapatite.

In one embodiment, the carrier material has an apatite content of from 70% by weight to 100% by weight, preferably from 80% by weight to 100% by weight, particularly preferably from 90% by weight to 100% by weight, based on the total weight of the unloaded carrier material. In one embodiment, the carrier material is apatite. It has been found that apatite can be used essentially as exclusive carrier material and is inert in taste and in the formation of the aerosol. The carrier material optionally has adjuvants. Such adjuvants include, but are not limited to stearates, particularly magnesium stearate, polyethylene glycols, polyethylene oxides and talc. The adjuvants can be used with advantage as Tablettierungshilfen.

In a further embodiment, the apatite has a specific surface area of more than 60 m ² / g, preferably more than 70 m ² / g, measured by the BET method according to DIN-ISO 9277 2003-05. In one embodiment, the apatite has a specific surface area of up to 250 m ² / g.

The proportion of fluid on the carrier material is preferably 2% by weight to 55% by weight, more preferably 5% by weight to 30% by weight, based on the total weight of the carrier material with fluid. It has been found that at this weight ratio, a particularly good and long-lasting aerosol development is achieved. Preferably, the carrier material is in the form of a pressed tablet. The term "tablet" refers to a pressed molding which is produced under pressure in tablet presses or other pressing tools known to the person skilled in the art.The pressing pressure preferably used for the production of such tablets advantageously lies in the range from 60 MPa to 300 MPa optional prepress pressure from 20 MPa to 100 MPa.

Conveniently, the tablet has a cylindrical or biconvex shape with a diameter in the range of 2 mm to 2 cm. The term "biconvex shape" generally refers to a generally circular shape in a plan view from below or above, which is curved upwards and downwards.A substantially round shape can have a circular shape but also slight deviations thereof, including regular ones Polygons (triangles, squares, pentagons, hexagons, heptagones, octagons, etc.) and oval shapes, as well as a tablet having a cylindrical shape whose base and top surfaces have a substantially circular shape as described above.

In alternative embodiments, the tobacco substitute is in a form obtained by extrusion, compaction, 3-D printing or injection molding. These methods provide greater shape variability. In a preferred embodiment, the fluid has a water content in the range of 0% to 50% by weight, based on the total volume of the fluid, preferably it has a water content of 0.5% to 10% by weight. on.

The invention further includes the use of apatite in a carrier material for a fluid in a tobacco substitute having the properties and features described herein. In one embodiment, apatite is used as a carrier material for a fluid in a tobacco substitute.

The invention further includes the use of the tobacco substitute set herein in a tobacco pipe or hookah.

Finally, the invention further comprises a process for the preparation of a tobacco substitute, in which one loads an apatite-comprising or consisting of apatite carrier material with a fluid, wherein

in a first step, the apatite and optional excipients in a mixer with stirring presents,

in a second step, the fluid is added with continued stirring and mixed with the presented apatite and optional excipients and

Forming the resulting mass in a third step or pressing into tablets. In one embodiment of the method according to the invention, a vacuum is further applied in the first step, which is maintained in the second step. The vacuum pulls the fluid into the mixer. Shaping in the third step can be done by extrusion, compaction or injection molding.

In one embodiment of the method according to the invention tablets are produced with a diameter in the range of 2 mm to 2 cm, wherein a pressing pressure of 60 MPa to 300 MPa is used and optionally a prepressing pressure of 20 to 100 MPa.

Examples

Example 1 - Aerosol Development and Aroma In this example, the aerosol development of different tobaccos or tobacco substitutes was compared.

For this purpose, a hydroxyapatite having a specific surface area of 80 m ² / g (CAS No. 1306-06-5; available from Chemische Fabrik Budenheim KG, Budenheim, Germany) was mixed with a commercially available aroma fluid containing glycerol, glucose, water, natural flavors and food coloring contained (raspberry flavor fluid, available from Aladin Shisha, Wiesbaden, Germany, website: www.bigg-steam.com). The apatite loaded with the aroma fluid was used as a mass pressed into tablets (sample b)). In another approach, an already used tablet according to sample b) was again loaded with aroma fluid (sample d)).

In sample b), loading of the apatite with 25% by weight of aroma fluid, based on the total weight of apatite and aroma fluid, was carried out before tableting. The tablets used in sample d) were prepared as for sample b) and, after being used in a hookah as described below, re-introduced into aroma fluid, using a clear excess of aroma fluid.

After mixing the ingredients for sample b) or sample d) before the first use, the mass was compressed in a tablet press with a pressure of 210 MPa to form tablets. Steam samples (Shiazo Steam Stones Raspberry, Shiazo / ASA GmbH) in sample a) and water pipe tobacco (Al Ajamy cherry flavor) in sample c) were used as comparative samples. For the experiment, a Wasserpfeifen Kopf was filled with the materials specified in Table 1, covered with a perforated aluminum foil and initiated a vapor or aerosol development by application of glowing coal.

Aerosol density was determined by visual comparison, and the developed aroma was subjectively evaluated by four subjects. The evaluation took place within 30 minutes after ignition of the hookah.

The evaluation was performed by indicating better (+), equal to (0) and worse (-) than sample b) as a reference. The results of the experiment are listed in Table 1, the last column indicating the respective ratings of the four subjects.

Table 1

The test persons evaluated the tobacco substitute according to the invention used as sample b) with respect to aroma / flavor and aerosol formation similar to the conventionally used flavored water pipe tobacco, but at least could not assign this to clear advantages over the tobacco substitute sample b). A conventional commercial tobacco substitute (sample a) likewise used in the experiment was rated worse in terms of both aerosol development and aroma / taste than a tobacco substitute according to the invention.

In addition, the reused tobacco substitute sample d) was rated similarly positive as sample b).

In addition to the results reported in Table 1, it has been found that tablets of the present invention already used can remain in flavor fluid for up to two hours without disintegration. This confirms that the tablets according to the invention can be loaded again with fluid and used after use. Example 2 - Long Term Use of Aromatherapy Loaded Apatite Tablets

In this experiment, it was tested whether an apatite-rich carrier material is able to provide a tobacco-like smelling experience during a typical period of water pipe consumption.

The tablets used for this experiment and loaded with aroma fluid had the following composition:

75% by weight of hydroxylapatatite (with a specific surface area of 80 m ² / g, Chemische Fabrik Budenheim KG)

25% by weight flavoring fluid (raspberry aroma fluid, www.bigg-steam.com)

For the preparation of the tablets, the apatite was loaded with the aroma fluid using a Stephan mixer. The apatite was presented in the mixer. Subsequently, the aroma fluid was added via a funnel. The fluid was evenly distributed in the apatite to be loaded by mixing. The loading process lasted 5 minutes. Subsequently, the apparatus was opened and small residues on the lid were returned to the mixture. There was a 1 minute post-mixing phase. The tableting was carried out in a tablet press (Fette 102i, Fette Compacting GmbH, Schwarzenbek, Germany) with a pressure of 105 MPa. The finished tablets had on average a mass of 396.1 mg and a breaking strength of 106 N (measured with a tablet tester from ERWEKA GmbH, Heusenstamm, Germany). In the experiment, a water pipe bowl was filled with water pipe tobacco (Sample aa)), tablets (Sample bb)) or commercially available steam stones (Sample cc), Aladin Shisha, Wiesbaden, Germany, Website: www.shiazo.com) with a perforated one Covered with aluminum foil and started steaming by burning red-hot coal. All samples were consumed for the usual 45-60 minutes.

The evaluation was carried out as described above for Example 1, using the pipe tobacco as a reference. The results are given in Table 2:

Table 2

Sample Material Aerosol Remarks

density

aa) Hookah tobacco with Himdicht Dichter steam. After 55 Minubeeraroma th still a pleasant taste, no scratching in the throat.

bb) tablets, dense right at the beginning density

25% Aromafluid steam development (30 sec), after 45 minutes the aroma became weaker and the steam less dense.

cc) Steamed raspberry flavored steam thin For the first 2 minutes very thin steam, no aroma. After 5 minutes the steam became denser but less strong than the tobacco. After 45 minutes the aroma faded and the vapor density decreased.

As in example 1, sample b) a dense aerosol comparable to the conventional tobacco (sample aa) could be provided when using sample bb). The duration of the possible use of 45 minutes is almost as long as with conventional water pipe tobacco, which is generally usable for about 60 minutes. In conventional steam stones, the vapor density was less high. In addition, it was possible to observe a dense formation of vapor in sample bb) immediately, while sample cc) showed noticeable evolution of vapor only after 5 minutes.

Claims

Patent claims

Tobacco substitute, in particular for use in a hookah, tobacco pipe or electric cigarette, comprising a liquid fluid and a carrier material for the fluid, characterized in that the carrier material comprises apatite.

2. Tobacco substitute according to claim 1, characterized in that the carrier material has an Apatitanteil of 70 wt .-% to 100 wt .-%, preferably 80 wt .-% to 100 wt .-%, particularly preferably 90 wt .-% to 100 Wt .-%, based on the total weight of the carrier material having.

3. Tobacco substitute according to one of claims 1 or 2, characterized in that the apatite has a specific surface area of more than 60 m ² / g, preferably more than 70 m ² / g, measured by the BET method according to DIN-ISO 9277 2003-05.

4. Tobacco substitute according to one of the preceding claims, characterized in that the carrier material is in the form of a pressed tablet and preferably the proportion of fluid on the carrier material is 2 wt .-% to 55 wt .-%, particularly preferably 5 wt .-% to 30 wt .-%, based on the total weight of the carrier material with fluid

5. Tobacco substitute according to one of the preceding claims, characterized in that the fluid has a water content in the range of 0 wt .-% to 50 wt .-%, based on the total volume of the fluid, preferably 0.5 wt .-% to 10 wt .-%, having.

6. Tobacco substitute according to one of the preceding claims, characterized in that the fluid comprises an active ingredient and / or flavoring.

7. Use of apatite in a carrier material for a fluid in a tobacco substitute.

8. Use of the tobacco substitute according to one of claims 1 to 6 in a tobacco pipe or hookah (Shisha).

9. A process for producing a tobacco substitute, which comprises loading an apatite-comprising or apatite existing carrier material with a fluid, wherein

in a second step, the fluid mixed with continued stirring and with the presented apatite and optional excipients and Forming the resulting mass in a third step or pressing into tablets.