WO2015165117A1 - 医用封堵系统 - Google Patents

医用封堵系统 Download PDF

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Publication number
WO2015165117A1
WO2015165117A1 PCT/CN2014/076686 CN2014076686W WO2015165117A1 WO 2015165117 A1 WO2015165117 A1 WO 2015165117A1 CN 2014076686 W CN2014076686 W CN 2014076686W WO 2015165117 A1 WO2015165117 A1 WO 2015165117A1
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WO
WIPO (PCT)
Prior art keywords
stent
outer layer
mandrel
tube
waist
Prior art date
Application number
PCT/CN2014/076686
Other languages
English (en)
French (fr)
Inventor
崔凯
李畅
李辉
杨明
张霞
Original Assignee
乐普（北京）医疗器械股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 乐普（北京）医疗器械股份有限公司 filed Critical 乐普（北京）医疗器械股份有限公司
Priority to PCT/CN2014/076686 priority Critical patent/WO2015165117A1/zh
Priority to US15/117,752 priority patent/US20160345943A1/en
Publication of WO2015165117A1 publication Critical patent/WO2015165117A1/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238—Type of minimally invasive operation
    • A61B2017/00243—Type of minimally invasive operation cardiac
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00597—Implements comprising a membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00606—Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00623—Introducing or retrieving devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00982—General structural features
    • A61B2017/00986—Malecots, e.g. slotted tubes, of which the distal end is pulled to deflect side struts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00982—General structural features
    • A61B2017/00991—Telescopic means

Definitions

  • the invention relates to the field of medical devices, and in particular to a medical sealing system. Background technique
  • the plugging system mainly includes a plugging bracket and a conveying device.
  • the plugging brackets of these products are made of nickel-titanium memory alloy wire and then heat-set.
  • the self-expanding plugging bracket is prepared by using the superelasticity of nickel-titanium alloy.
  • the human body's demand for the device is not long-term.
  • the inner membrane will be completely covered in about 3 months.
  • the blocking stent is a useless foreign object, and is accompanied by various side effects such as nickel ion dissolution and destruction of human tissue. Wait.
  • the use of the existing platform to prepare the degradable material to block the stent is prone to retraction, resulting in insufficient clamping force and surgical failure. Summary of the invention
  • the present invention provides a medical occlusion system comprising a occlusion stent and a delivery device, the occlusion stent comprising an outer layer of the stent, a membrane disposed on the outer layer of the stent, and a mandrel disposed in the outer layer of the stent;
  • the distal end of the mandrel is fixedly connected to the distal end of the outer layer of the stent;
  • the occlusion bracket is made of a degradable polymer;
  • the conveying device comprises an outer push tube and an inner push rod disposed in the outer push tube, The outer push tube and the inner push rod are axially movable relative to each other; the outer push tube is movably connected to the proximal end of the outer sleeve; and the inner push rod is movably connected to the proximal end of the mandrel.
  • the proximal end of the mandrel is provided with a snap ring.
  • the snap ring is a protrusion disposed at an outer edge of the proximal end of the mandrel.
  • the outer layer of the bracket is provided with a bracket waist, and when the outer layer of the bracket is unfolded, an outer surface of the outer layer of the outer sleeve forms an upper surface with the waist of the bracket; a proximal end of the outer layer of the bracket and the bracket The lower surface is formed between the waist.
  • bracket waist is connected to the outer end of the outer layer of the bracket and the outer end of the outer layer of the bracket by a plurality of bracket beams; the film is disposed between any two adjacent bracket beams; the bracket beam The middle part has a bend.
  • the waist of the bracket is a telescopic structure, and the length and diameter thereof can be determined according to requirements.
  • the proximal end and the distal end of the stent are connected by a plurality of waist beams.
  • the outer layer of the bracket is a braided tube woven from a spirally intersecting ribbon, and the middle portion of the braided tube is provided with a bracket waist.
  • the inner pushing rod is provided with a connection for connecting with the mandrel, and the proximal end of the mandrel is provided with a guiding hole for engaging with the connecting guiding portion.
  • the conveying device further comprises an outer sheath tube, wherein the outer push tube set is outside And the outer push tube is axially movable along the outer sheath tube.
  • the medical occlusion system provided by the invention delivers the occlusion stent to the position required for the treatment by the conveying device, and unfolds the outer layer of the stent, and disengages from the conveying device, thereby releasing the occlusion stent to the position required for the treatment, and completing the sealing.
  • Figure 1 is a perspective structural view of Embodiment 1 of the present invention.
  • Figure 2 is a view of the axial end of the plugging bracket in the first embodiment of the present invention
  • Figure 3 is a front elevational view showing the occluding stent in an unexpanded state in the first embodiment of the present invention
  • Figure 4 is a perspective view showing the membrane removed in the first embodiment of the present invention
  • Figure 5 is a front elevational view of Embodiment 2 of the present invention
  • Figure 6 is a front elevational view showing the unfolded state of the plugging bracket in the second embodiment of the present invention
  • Figure 7 is a perspective view showing a third embodiment of the present invention.
  • bracket waist 6 bracket beam
  • bracket waist 6 bracket beam
  • 7 snap ring
  • 8 mandrel
  • 9 connecting guide
  • Inner push rod 11: external push tube
  • 12 outer sheath tube
  • 13 bent portion
  • 100 plugging bracket
  • 200 conveying device.
  • a medical occlusion system of the present invention includes a occlusion stent 100 and a delivery device 200.
  • the occlusion stent 100 includes a stent outer layer 1, a membrane 3 disposed on the stent outer layer 1, and a wearer.
  • the outer layer 1 of the stent can be spread, and the film 3 disposed on the outer layer 1 of the stent is unfolded to form a disk surface structure, and the unfolded stent 100 has a sealing function.
  • the distal end of the mandrel 8 is fixedly connected to the distal end of the outer layer 1 of the stent.
  • the sealing stent 100 is made of a degradable polymer.
  • the degradable polymer may be silk fibroin, PLA (polylactic acid), PGA (polyglycolic acid), PGLA (polyethylene lactide) or a composite material.
  • the conveying device 200 comprises an outer sheath tube 12, an outer pushing tube 11 and an inner pushing rod 10 which is arranged in the outer pushing tube.
  • the outer pushing tube 11 and the inner pushing rod 10 can move relative to each other in the axial direction; the outer pushing tube 11 and the outer bracket The proximal end of the layer 1 is movably connected; the inner push rod 10 is movably connected to the proximal end of the mandrel 8; the outer push tube 11 is fitted in the outer sheath tube 12, and the outer push tube 11 is axially movable along the outer sheath tube 12.
  • the outer layer of the bracket 1 and the outer push tube 11 can be connected by a controllable connection such as a rotary type.
  • the inner push rod 10 is connected to the proximal end of the mandrel 8, and the outer push tube 11 and the outer bracket
  • the proximal end of the layer 1 is connected, and the outer push tube 11 is axially moved along the inner push rod 10 to move the proximal end of the outer layer 1 of the bracket to the distal end, and the outer layer of the outer layer of the bracket is deformed according to a pre-designed trend path to form
  • the disc surface structure finally achieves the purpose of deformation of the entire plugging bracket.
  • the outer push tube 11 and the inner push rod 10 By operating the outer push tube 11 and the inner push rod 10, the outer push tube 11 and the inner push rod 10 are separated from the outer layer 1 of the stent 1 and the mandrel 8, respectively, thereby releasing the position of the occlusion stent 100 at a designated treatment, as needed.
  • the plugging bracket can also be recycled.
  • the medical occlusion system transports the occlusion stent to the position required for the treatment by the delivery device, and unfolds the outer layer of the stent, and disengages from the delivery device, thereby releasing the occlusion stent to the position required for the treatment, completing the sealing operation, and using Convenient to prevent the blocking bracket from returning to its original position.
  • the occlusion stent of the invention is made of a degradable polymer material, and can be self-degraded after the occlusion stent 100 enters the human body, thereby eliminating the hidden troubles caused by the residual interference of the prior art occlusion stent in the human body.
  • a snap ring 7 is disposed on the proximal end of the mandrel 8.
  • the mandrel 8 can be a cylinder having a regular polygonal, elliptical or circular cross section. In this embodiment, the mandrel 8 is preferably a circular cylinder.
  • the ring 7 is a projection disposed at the outer edge of the proximal end of the mandrel. The purpose is to ensure that the proximal end of the outer layer 1 of the stent can be strongly restrained when it reaches the corresponding position on the mandrel, ensuring that the outer layer of the stent cannot rebound freely and remain sealed.
  • the outer layer 1 of the bracket is provided with a bracket waist 5, and when the outer layer 1 of the bracket is unfolded, an upper disc surface 2 is formed between the distal end of the outer layer 1 of the bracket and the waist 5 of the bracket; between the proximal end of the outer layer 1 of the bracket and the waist 5 of the bracket The lower disk surface 4 is formed.
  • the bracket waist 5 is preferably disposed in the middle of the outer layer 1 of the bracket.
  • bracket waist 8 and the proximal end of the outer layer 1 of the bracket and between the distal ends of the outer layer 1 of the bracket are respectively connected by a plurality of bracket beams 6; the membrane 3 is disposed between any adjacent two bracket beams 6; A bent portion 13 is provided in the middle of the beam 6.
  • the bracket beam 6 is bent along the bent portion 13, and the film 3 is opened to form a disc surface structure.
  • the outer layer 1 of the bracket can be engraved by integral pipe or processed by strip and wire processing.
  • the diameter of the bracket waist 5 is a retractable structure, and its length and diameter can be determined as needed.
  • the bracket waist 5 can take a mesh structure.
  • the mandrel 8 and the inner push rod 10 can take all controllable connections such as threading or clamping.
  • the inner push rod 10 is radially rotatable along the outer push tube 11.
  • the inner push rod 10 is provided with a joint guide portion 9 for connection with the mandrel 8, and the proximal end of the mandrel 8 is provided with a guide hole (not shown) that engages with the joint guide portion 9.
  • the delivery device further includes a handle (not shown) for controlling the axial movement of the inner push rod 10 and the outer push tube 11 for treatment.
  • This embodiment is basically the same as the first embodiment except that, as shown in FIG. 5 and FIG. 6, the outer layer 1 of the stent of the occlusion stent 100 is a braided tube woven from a spirally intersecting ribbon, a braided tube.
  • the middle section is provided with a bracket waist 5, which has a certain deformation function.
  • This embodiment is basically the same as Embodiment 1, except that, as shown in FIG. 7, the proximal end of the stent waist and the distal end are connected by a plurality of waist beams, and when the external push tube pushes the proximal end of the outer layer of the stent When the push rod moves, the waist beam is flared outwards to shorten the waist.
  • the occlusion bracket recovery means that the outer push tube and the outer end of the outer sleeve of the bracket can be detached or reconnected before the mandrel and the inner push rod are detached, and the deformed occlusion bracket is retracted into strips. Or tubular, and then retracted into the outer sheath; the release of the occluded stent means that after the proximal end of the outer layer of the stent reaches the design position, the outer proximal and outer push tubes of the outer detachment are separated from the outer end of the outer shaft and then pushed The rod keeps the blocking bracket in the intended position.
  • the invention provides a medical occlusion system, comprising a occlusion bracket and a conveying device, the occlusion bracket comprising an outer layer of the bracket, a membrane disposed on the outer layer of the bracket and the outer layer of the bracket a mandrel; a distal end of the mandrel is fixedly connected to the distal end of the outer layer of the stent; the blocking bracket is made of a degradable polymer; the conveying device comprises an outer pushing tube and an inner pushing rod set in the outer pushing tube, the outer pushing tube and the inner pushing tube The rods are relatively movable in the axial direction; the outer push tube is movably connected to the proximal end of the outer layer of the stent; the inner push rod is movably connected to the proximal end of the mandrel.
  • the invention can transport the occlusion stent to the position required for the treatment by the conveying device, and unfold the outer layer of the stent, and disengage from the conveying device, thereby releasing the occlusion stent to the position required for the treatment, completing the sealing operation and preventing the sealing.
  • the stent is returned to the original position; the sealing stent is made of a degradable polymer material, and the sealing stent can self-degrade after entering the human body, thereby eliminating the hidden troubles of the side effects caused by the blocking stent remaining in the human body.

Abstract

一种医用封堵系统，包括封堵支架（100）和输送装置（200），封堵支架（100）包括支架外层（1）、设置在支架外层（1）上的膜（3）以及穿设在支架外层（1）中的芯轴（8）；芯轴（8）远端与支架外层（1）远端固定连接；封堵支架（100）由可降解聚合物制成；输送装置（200）包括外推送管（11）和套装在外推送管（11）中的内推送杆（10），两者之间可沿轴向相对运动；外推送管（11）与支架外层（1）近端活动连接；内推送杆（10）与芯轴（8）近端活动连接。该医用封堵系统在进入人体后能够自行降解，消除了封堵支架残留在人体内会造成的副作用的隐患。

Description

医用封堵系统 技术领域
本发明涉及医疗器械领域， 尤其涉及一种医用封堵系统。 背景技术
先天性心脏病介入治疗已经很普遍了，封堵系统是介入治疗的主 要器械。 封堵系统主要包括封堵支架和输送装置。 目前国内外的很多 公司都有产品上巿，然而这些产品的封堵支架都是使用镍钛记忆合金 丝编制， 然后热定型； 利用镍钛合金的超弹性， 制备成自膨胀式封堵 支架。 但是人体对器械的需求不是长期的， 在 3个月左右内膜就会被 全部覆盖， 此时， 封堵支架就是一个无用的异物， 并且伴随有各种副 作用， 如镍离子溶出、 破坏人体组织等。 另外， 采用现有平台制备可 降解材料封堵支架容易产生回缩， 导致夹持力不够而手术失败。 发明内容
(一） 要解决的技术问题
本发明的目的在于提供医用封堵系统，用以解决封堵支架自动回 缩及难以降解的问题。
(二）技术方案
本发明提供一种医用封堵系统， 包括封堵支架和输送装置， 所述 封堵支架包括支架外层、设置在所述支架外层上的膜以及穿设在支架 外层中的芯轴； 所述芯轴远端与支架外层远端固定连接； 所述封堵支 架由可降解聚合物制成；所述输送装置包括外推送管和套装在所述外 推送管中的内推送杆，所述外推送管与内推送杆之间可沿轴向相对运 动； 所述外推送管与所述支架外层近端活动连接； 所述内推送杆与芯 轴近端活动连接。
其中， 所述芯轴近端设置有卡环。
优选的， 所述卡环为设置在所述芯轴近端外沿的凸起。 其中， 所述支架外层上设有支架腰， 所述支架外层展开时， 所述 支架外层远端与所述支架腰之间形成上盘面；所述支架外层近端与所 述支架腰之间形成下盘面。
其中， 所述支架腰与支架外层近端、 支架外层远端之间分别通过 多个支架梁连接； 所述膜设置在任意相邻的两个所述支架梁之间； 所 述支架梁的中部设有折弯部。
其中， 所述支架腰为可伸缩结构， 其长度和直径可以根据需要而 定。
其中， 所述支架腰近端和远端之间通过多个腰梁连接。 其中， 所述支架外层为由螺旋交叉的丝带编织而成的编织管， 所 述编织管的中段设有支架腰。
其中， 所述内推送杆设有一个用于与所述芯轴连接的连接导向 所述芯轴近端设有与所述连接导向部配合的导向孔。 其中， 所述输送装置还包括外鞘管， 所述外推送管套装在所述外
Figure imgf000004_0001
中， 且所述外推送管可沿所述外鞘管轴向运动。
(三）有益效果
本发明提供的医用封堵系统，通过输送装置将封堵支架输送到治 疗所需要的位置， 并将支架外层展开， 脱离输送装置， 从而使封堵支 架释放到治疗所需要的位置， 完成封堵作业， 防止封堵支架回复原始 位置； 本发明的封堵支架使用的是可降解聚合物材质， 本发明提供的 医用封堵系统在进入人体后能够自行降解，消除了封堵支架残留在人 体内会造成的副作用的隐患。 附图说明
图 1是本发明实施例 1的立体结构图；
图 2是本发明实施例 1中沿封堵支架轴端的视图；
图 3是本发明实施例 1中封堵支架在未展开状态的主视图; 图 4是本发明实施例 1略去膜的立体图； 图 5是本发明实施例 2的主视图；
图 6为本发明实施例 2中的封堵支架未展开状态的主视图； 图 7为本发明实施例 3的立体图。
图中， 1 : 支架外层； 2: 上盘面； 3: 膜； 4: 下盘面； 5: 支架 腰 6: 支架梁； 7: 卡环； 8: 芯轴； 9: 连接导向部； 10: 内推送杆； 11 : 外推送管； 12: 外鞘管； 13: 折弯部； 100: 封堵支架； 200: 输 送装置。 具体实施方式
下面结合附图和实施例， 对本发明的具体实施方式做进一步描 述。
实施例 1
参见图 1至 4所示， 本发明的一种医用封堵系统， 包括封堵支架 100和输送装置 200， 封堵支架 100包括支架外层 1、 设置在支架外 层 1上的膜 3以及穿设于支架外层 1中的芯轴 8。 支架外层 1能够展 开， 使设置在支架外层 1上的膜 3展开形成盘面结构， 展开的封堵支 架 100具有封堵功能。 芯轴 8远端与支架外层 1远端固定连接， 在封 堵支架 100上， 芯轴 3与支架外层 1相固定的一端称之为远端 (参照 图 1的左端）， 相应的， 另外一端称之为近端（参照图 1的右端）。 封 堵支架 100由可降解聚合物制成。可降解聚合物可以为丝素蛋白、 PLA (聚乳酸）、 PGA (聚乙醇酸）、 PGLA (聚乙丙交酯）或复合材料等。 输送装置 200包括外鞘管 12、 外推送管 11和套装在外推送管中的内 推送杆 10， 外推送管 11与内推送杆 10之间可沿轴向相对运动； 外 推送管 11与支架外层 1近端活动连接； 内推送杆 10与芯轴 8近端活 动连接； 外推送管 11套装在外鞘管 12中， 且外推送管 11可沿外鞘 管 12轴向运动。支架外层 1近端和外推送管 11可以采取旋转式等一 切可控的连接方式进行连接。
使用时， 内推送杆 10与芯轴 8近端连接， 外推送管 11与支架外 层 1近端连接， 外推送管 11沿内推送杆 10轴向移动， 使支架外层 1 近端向远端移动，支架外层 1支架外层按照预先设计好的趋势路径进 行变形展开， 形成盘面结构， 最终达到整个封堵支架变形的目的。 通 过操作外推送管 11和内推送杆 10 ， 使外推送管 11和内推送杆 10 分别与支架外层 1、 芯轴 8分离， 从而释放封堵支架 100在指定治疗 所需的位置， 根据需要也可以回收封堵支架。
医用封堵系统，通过输送装置将封堵支架输送到治疗所需要的位 置， 并将支架外层展开， 脱离输送装置， 从而使封堵支架释放到治疗 所需要的位置， 完成封堵作业， 使用方便， 防止封堵支架回复原始位 置。 本发明的封堵支架使用的是可降解聚合物材质， 在封堵支架 100 进入人体后能够自行降解，消除了现有技术封堵支架残留在人体内会 造成的副作用的隐患。
进一步的， 在芯轴 8近端上设置有卡环 7， 芯轴 8可以采用横截 面为正多边形、椭圆形或者圆形的柱体， 本实施例优选芯轴 8为圆形 柱体， 卡环 7为设置在芯轴近端外沿的凸起。 目的是为了保证支架外 层 1近端到达芯轴上相应位置时能够得到有力的束缚，确保支架外层 展开后无法自由回弹而保持封堵状态。
进一步的， 支架外层 1上设有支架腰 5， 支架外层 1展开时， 支 架外层 1远端与支架腰 5之间形成上盘面 2; 支架外层 1近端与支架 腰 5之间形成下盘面 4。 支架腰 5优选设置在支架外层 1的中段。
进一步的， 支架腰 8与支架外层 1近端之间、 支架外层 1远端之 间分别通过多个支架梁 6连接； 膜 3设置在任意相邻的两个支架梁 6 之间； 支架梁 6的中部设有折弯部 13。 在外推送管 11带动支架外层 近端移动时， 支架梁 6沿折弯部 13弯曲， 膜 3张开， 形成盘面结构。 支架外层 1可以通过整体管材雕刻或者采用条状物、丝材加工焊接加 工而成。
进一步的， 为了保证封堵支架能够扩张到治疗需要的长度和直 径， 支架腰 5为可伸缩结构， 其长度和直径可以根据需要而定。 支架 腰 5可以采取网状结构。
进一步的， 芯轴 8和内推送杆 10可以采取螺紋或者夹持等一切 可以控制的连接方式。 当选择螺紋连接时， 内推送杆 10可沿外推送 管 11径向转动。本实施例优选内推送杆 10设有一个用于与芯轴 8连 接的连接导向部 9， 芯轴 8的近端设有与连接导向部 9配合的导向孔 (图未示出）。 通过连接导向部 9和扣座连接， 提高内推送杆 10与芯 轴 8的对接准确度， 防止内推送杆 10与芯轴 8发生偏离， 导致手术 失败。
进一步的， 输送装置还包括手柄 （图未示出）， 手柄用于控制内 推送杆 10、 外推送管 11的轴向运动， 以进行治疗。
实施例 2
本实施例与实施例 1基本相同， 所不同之处在于， 参照图 5和图 6所示， 该封堵支架 100的支架外层 1为由螺旋交叉的丝带编织而成 的编织管， 编织管的中段设有支架腰 5， 具备一定变形的功能。
实施例 3
本实施例与实施例 1基本相同， 所不同之处在于， 如图 7所示， 支架腰近端和远端之间通过多个腰梁连接， 当外推送管推动支架外层 近端沿内推送杆移动时， 腰梁向外展开支架腰缩短。
本发明所述的封堵支架回收是指， 在芯轴和内推送杆脱离前， 外 推送管和支架外层近端可以脱离或重新连接，并且把变形后的封堵支 架重新收回成条状或管状， 进而收回到外鞘管里； 封堵支架的释放是 指，支架外层近端到达设计位置后，先脱离支架外层近端和外推送管， 然后脱离芯轴近端和内推送杆， 使封堵支架留在目的位置。 工业实用性
本发明提供一种医用封堵系统， 包括封堵支架和输送装置， 封堵 支架包括支架外层、设置在支架外层上的膜以及穿设在支架外层中的 芯轴； 芯轴远端与支架外层远端固定连接； 封堵支架由可降解聚合物 制成； 输送装置包括外推送管和套装在外推送管中的内推送杆， 外推 送管与内推送杆之间可沿轴向相对运动；外推送管与支架外层近端活 动连接； 内推送杆与芯轴近端活动连接。 本发明通过输送装置能够将 封堵支架输送到治疗所需要的位置， 并将支架外层展开， 脱离输送装 置， 从而使封堵支架释放到治疗所需要的位置， 完成封堵作业， 防止 封堵支架回复原始位置； 封堵支架使用的是可降解聚合物材质， 封堵 支架在进入人体后能够自行降解，消除了封堵支架残留在人体内会造 成的副作用的隐患。

Claims

权 利 要 求 书
1、 一种医用封堵系统， 包括封堵支架和输送装置， 其特征在于: 所述封堵支架包括支架外层、设置在所述支架外层上的膜以及穿设在 支架外层中的芯轴； 所述芯轴远端与支架外层远端固定连接； 所述封 堵支架由可降解聚合物制成；所述输送装置包括外推送管和套装在所 述外推送管中的内推送杆，所述外推送管与内推送杆之间可沿轴向相 对运动； 所述外推送管与所述支架外层近端活动连接； 所述内推送杆 与芯轴近端活动连接。
2、 根据权利要求 1所述医用封堵系统， 其特征在于： 所述芯轴 近端设置有卡环。
3、 根据权利要求 2所述医用封堵系统， 其特征在于： 所述卡环 为设置在所述芯轴近端外沿的凸起。
4、 根据权利要求 1所述医用封堵系统， 其特征在于： 所述支架 外层上设有支架腰， 所述支架外层展开时， 所述支架外层远端与所述 支架腰之间形成上盘面；所述支架外层近端与所述支架腰之间形成下 盘面。
5、 根据权利要求 4所述医用封堵系统， 其特征在于： 所述支架 腰与支架外层近端、 支架外层远端之间分别通过多个支架梁连接； 所 述膜设置在任意相邻的两个所述支架梁之间；所述支架梁的中部设有 折弯部。
6、 根据权利要求 4所述医用封堵系统， 其特征在于： 所述支架 腰为可伸缩结构， 其长度和直径可以根据需要而定。
7、 根据权利要求 6所述医用封堵系统， 其特征在于： 所述支架 腰近端和远端之间通过多个腰梁连接。
8、 根据权利要求 1所述医用封堵系统， 其特征在于： 所述支架 外层为由螺旋交叉的丝带编织而成的编织管，所述编织管的中段设有 支架腰。
9、 根据权利要求 1所述医用封堵系统， 其特征在于： 所述内推 送杆设有一个用于与所述芯轴连接的连接导向部，所述芯轴近端设有 与所述连接导向部配合的导向孔。
10、 根据权利要求 1所述医用封堵系统， 其特征在于： 所述输送 装置还包括外鞘管， 所述外推送管套装在所述外鞘管中， 且所述外推 送管可沿所述外鞘管轴向运动。
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017210356A1 (en) * 2016-06-02 2017-12-07 Medtronic Vascular Inc. Transcatheter valve delivery system with septum hole closure tip assembly
US10016188B2 (en) 2015-02-10 2018-07-10 Teleflex Innovation S.à.r.l. Closure device for sealing percutaneous opening in a vessel

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1875894A (zh) * 2006-07-06 2006-12-13 何健峰 先天性心脏病封堵装置
US20120065667A1 (en) * 2010-07-02 2012-03-15 Alex Javois Left atrial appendage occlusion device
CN102895008A (zh) * 2012-09-28 2013-01-30 乐普（北京）医疗器械股份有限公司 医用封堵器及其输送系统
CN203153824U (zh) * 2013-04-02 2013-08-28 乐普（北京）医疗器械股份有限公司 一种心脏缺损封堵器

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070129755A1 (en) * 2005-12-05 2007-06-07 Ovalis, Inc. Clip-based systems and methods for treating septal defects
US20040254594A1 (en) * 2003-01-24 2004-12-16 Arthur Alfaro Cardiac defect occlusion device
WO2004082532A1 (en) * 2003-03-17 2004-09-30 Ev3 Sunnyvale, Inc. Thin film composite lamination
EP2481356B1 (en) * 2003-07-14 2013-09-11 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
EP1748732A1 (en) * 2004-05-07 2007-02-07 NMT Medical, Inc. Catching mechanisms for tubular septal occluder
WO2007016261A2 (en) * 2005-07-29 2007-02-08 Cvdevices, Llc Magnetic devices and methods for septal occlusion
EP1962695A1 (en) * 2005-12-22 2008-09-03 NMT Medical, Inc. Catch members for occluder devices
CA2646825A1 (en) * 2006-03-31 2007-10-11 Nmt Medical, Inc. Adjustable length patent foramen ovale (pfo) occluder and catch system
WO2007115125A2 (en) * 2006-03-31 2007-10-11 Nmt Medical, Inc. Deformable flap catch mechanism for occluder device
US9119607B2 (en) * 2008-03-07 2015-09-01 Gore Enterprise Holdings, Inc. Heart occlusion devices
US20100030321A1 (en) * 2008-07-29 2010-02-04 Aga Medical Corporation Medical device including corrugated braid and associated method
US9241696B2 (en) * 2008-10-30 2016-01-26 Abbott Vascular Inc. Closure device
SG183140A1 (en) * 2010-02-05 2012-09-27 Univ Nanyang Tech Occlusion device for closing anatomical defects
CN104487024B (zh) * 2012-03-16 2017-08-29 微仙美国有限公司 支架和支架送递装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1875894A (zh) * 2006-07-06 2006-12-13 何健峰 先天性心脏病封堵装置
US20120065667A1 (en) * 2010-07-02 2012-03-15 Alex Javois Left atrial appendage occlusion device
CN102895008A (zh) * 2012-09-28 2013-01-30 乐普（北京）医疗器械股份有限公司 医用封堵器及其输送系统
CN203153824U (zh) * 2013-04-02 2013-08-28 乐普（北京）医疗器械股份有限公司 一种心脏缺损封堵器

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10016188B2 (en) 2015-02-10 2018-07-10 Teleflex Innovation S.à.r.l. Closure device for sealing percutaneous opening in a vessel
US10722225B2 (en) 2015-02-10 2020-07-28 Teleflex Life Sciences Limited Closure device for sealing percutaneous opening in a vessel
WO2017210356A1 (en) * 2016-06-02 2017-12-07 Medtronic Vascular Inc. Transcatheter valve delivery system with septum hole closure tip assembly
CN109152641A (zh) * 2016-06-02 2019-01-04 美敦力瓦斯科尔勒公司 具有隔膜孔闭合末端组件的经导管瓣膜递送系统
US10449044B2 (en) 2016-06-02 2019-10-22 Medtronic Vascular, Inc. Transcatheter valve delivery system with septum hole closure tip assembly
CN109152641B (zh) * 2016-06-02 2020-08-21 美敦力瓦斯科尔勒公司 具有隔膜孔闭合末端组件的经导管瓣膜递送系统
EP3791828A1 (en) * 2016-06-02 2021-03-17 Medtronic Vascular Inc. Transcatheter valve delivery system with septum hole closure tip assembly
US11273035B2 (en) 2016-06-02 2022-03-15 Medtronic Vascular, Inc. Occluder

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