WO2015102078A1 - Ensemble de perfusion, dispositif de commande commandant son entraînement, et ensemble de perfusion avec fonction d'administration de médicament en étant doté - Google Patents

Ensemble de perfusion, dispositif de commande commandant son entraînement, et ensemble de perfusion avec fonction d'administration de médicament en étant doté Download PDF

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Publication number
WO2015102078A1
WO2015102078A1 PCT/JP2014/083798 JP2014083798W WO2015102078A1 WO 2015102078 A1 WO2015102078 A1 WO 2015102078A1 JP 2014083798 W JP2014083798 W JP 2014083798W WO 2015102078 A1 WO2015102078 A1 WO 2015102078A1
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WO
WIPO (PCT)
Prior art keywords
chemical solution
infusion set
chemical
pump
container
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Application number
PCT/JP2014/083798
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English (en)
Japanese (ja)
Inventor
山田　圭一
晃子 北籔
正行 漆間
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大研医器株式会社
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Publication of WO2015102078A1 publication Critical patent/WO2015102078A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14224—Diaphragm type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1413—Modular systems comprising interconnecting elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M2005/16863—Occlusion detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0272—Electro-active or magneto-active materials
    • A61M2205/0294—Piezoelectric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3317—Electromagnetic, inductive or dielectric measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3375—Acoustical, e.g. ultrasonic, measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3569—Range sublocal, e.g. between console and disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
    • A61M5/365—Air detectors

Definitions

  • the present invention relates to an infusion set for guiding a chemical solution in a chemical solution container to a patient while being connected to the chemical solution container that stores the chemical solution.
  • Patent Document 1 an infusion system for administering a drug solution in an infusion bag to a patient is known.
  • the infusion system described in Patent Document 1 includes an infusion set including a flexible tube connected to an infusion bag, and an infusion pump that pushes the drug solution in the flexible tube toward the patient.
  • the infusion pump has a peristaltic pump section having a plurality of fingers.
  • the peristaltic pump unit crushes the flexible tube sequentially from the outside of the flexible tube from the suction side to the discharge side by performing a peristaltic movement of the plurality of fingers. Thereby, the chemical solution in the flexible tube is pushed away from the suction side to the discharge side in the flexible tube.
  • the infusion set may be connected to a syringe that stores a chemical solution.
  • the drug solution in the syringe is swept away by, for example, an infusion device described in Patent Document 2.
  • the infusion device described in Patent Document 2 has a pressing mechanism that pushes the plunger into the outer cylinder of the syringe.
  • the pressing mechanism pushes the plunger into the outer cylinder of the syringe.
  • the infusion set is removed from the infusion pump described in Patent Document 1 or the infusion device described in Patent Document 2, and discarded together with a chemical solution bag or a syringe to prevent infection.
  • the present invention is an infusion set for guiding a chemical solution in the chemical solution container to a patient while being connected to the chemical solution container that stores the chemical solution, and accepting the chemical solution from the chemical solution container
  • a connecting portion connectable to the chemical solution container to permit, a derivation portion for deriving the chemical solution received from the chemical solution container via the connection portion, and for guiding the chemical solution from the connection portion to the derivation portion.
  • connection portion A conduit provided between the connection portion and the lead-out portion, a connection conductor, a piezoelectric element that repeats expansion and contraction by a driving voltage supplied via the connection conductor, and expansion and contraction of the piezoelectric element
  • a pump that has a diaphragm that vibrates due to contraction, and that applies a force to the chemical solution to be derived through the deriving unit in response to the supply of the drive voltage, and for supplying the drive voltage to the pump Control unit and the connection conductor and has a mounting portion for mounting detachably said control device in a state of being electrically connected to provide an infusion set.
  • FIG. 1 is a perspective view showing the overall configuration of an infusion set with a chemical solution feeding function according to the first embodiment of the present invention.
  • FIG. 2 is an exploded perspective view of the infusion set with a chemical solution feeding function shown in FIG. 3 is a cross-sectional view taken along line III-III in FIG. 4 is a cross-sectional view taken along line IV-IV in FIG.
  • FIG. 5 is a cross-sectional view for explaining the operation of the pump, and shows a state where the drive voltage is not supplied.
  • FIG. 6 is a cross-sectional view for explaining the operation of the pump, and shows a state where the pump chamber is expanded.
  • FIG. 7 is a cross-sectional view for explaining the operation of the pump, and shows a state where the pump chamber is contracted.
  • FIG. 8 is a cross-sectional view taken along line VIII-VIII in FIG.
  • FIG. 9 is a block diagram showing an electrical configuration of the infusion set with a chemical solution feeding function shown in FIG.
  • FIG. 10 is a perspective view showing the overall configuration of an infusion set with a chemical solution feeding function according to the second embodiment of the present invention.
  • FIG. 11 is an exploded perspective view of the infusion set with a chemical solution feeding function shown in FIG. 12 is a cross-sectional view taken along line XII-XII in FIG. 13 is a cross-sectional view taken along line XIII-XIII in FIG. 14 is a cross-sectional view taken along line XIV-XIV in FIG.
  • FIG. 15 is a circuit diagram showing an example of the switching valve, and shows a state in which the pump is stopped and the pressure of the chemical solution in the infusion bag is lower than the reference pressure.
  • FIG. 16 is a circuit diagram showing an example of the switching valve, and shows a state where the pressure of the chemical solution in the infusion bag is equal to or higher than the reference pressure.
  • FIG. 17 is a view corresponding to FIG. 14 of the chemical solution feeding section according to the third embodiment of the present invention.
  • FIG. 18 is a perspective view showing an overall configuration of an infusion set with a chemical solution feeding function according to the fourth embodiment of the present invention.
  • FIG. 19 is a side cross-sectional view of the infusion set shown in FIG. 20 is a cross-sectional view of the control device shown in FIG. 18 when viewed from the back.
  • FIG. 21 is a perspective view showing an overall configuration of an infusion set with a drug solution feeding function according to the fifth embodiment of the present invention.
  • the infusion bag B1 includes a bag main body B2 that stores the chemical liquid, and a port B3 that is provided at one end of the bag main body B2 and leads out the chemical liquid in the bag main body B2.
  • the port B3 includes a cylindrical main body and a rubber plug B4 provided in the main body.
  • An infusion set 1A with a medicinal solution feeding function includes an infusion set 2 for guiding medicinal solution in the infusion bag B1 to a patient, and a control device 3 that is detachably attached to the infusion set 2 and controls the medicinal solution feeding operation by the infusion set 2. And.
  • the control device 3 is re-used.
  • the infusion set 2 leads out the medicinal solution received from the infusion bag B1 through the connection portion 4 that can be connected to the port B3 of the infusion bag B1 so as to allow the acceptance of the medicinal solution from the infusion bag B1.
  • medical solution sending part 7 which sends
  • the side where the connection part 4 in the infusion set 2 is provided is referred to as a proximal end side
  • the side where the outlet part 5 is provided is referred to as a distal end side.
  • the lead-out unit 5 includes a catheter and an injection needle, and is configured to be connectable to an indwelling member that is indwelled in the patient's body.
  • the lead-out part 5 itself may be an indwelling member.
  • the connecting portion 4 includes a needle 4a for penetrating the rubber plug B4 of the infusion bag B1, and a port B3 of the infusion bag B1 so that the needle 4a is prevented from coming off from the rubber plug B4 with the needle 4a passing through the rubber plug B4.
  • Engaging portion 4b is provided.
  • the needle 4a has a communication hole provided in a range from the distal end portion to the proximal end portion. When the needle 4a passes through the rubber plug B4, the chemical solution is introduced into the needle 4a through the communication hole.
  • the conduit 6 includes a first conduit 6a that extends from the chemical solution feed section 7 described later to the proximal end side, and a second conduit 6b that extends from the chemical solution feed section 7 to the distal end side.
  • the proximal end portion of the first conduit 6a is connected to the distal end portion of the needle 4a, allows the chemical solution introduced through the needle 4a to be accepted, and guides it to the chemical solution feeding portion 7.
  • the second conduit 6 b guides the chemical solution sent from the chemical solution feeding unit 7 to the derivation unit 5.
  • the chemical solution feeder 7 includes a connecting member 10 that connects the first conduit 6a and the second conduit 6b, a pump 11 connected to the connecting member 10, a first conduit 6a, A case 8 and a lid 9 are provided for housing the connecting member 10 and the pump 11 with the second conduit 6b penetrating therethrough.
  • the connecting member 10 has a first chamber and a second chamber (reference numerals omitted) that are partitioned so as not to communicate with each other.
  • the first chamber communicates with the first conduit 6a, and the second chamber communicates with the second conduit 6b.
  • the connecting member 10 has an inlet side opening 10 a that communicates the first chamber and the outside of the connecting member 10, and an outlet side opening 10 b that communicates the second chamber and the outside of the connecting member 10.
  • the inlet side opening 10a communicates with an inlet 12b of the pump 11 described later
  • the outlet side opening 10b communicates with an outlet 12c of the pump 11 described later.
  • a seal member 11a (see FIG. 5) is provided so that the communication between the inlet-side opening 10a and the inlet 12b and the communication between the outlet-side opening 10b and the outlet 12c are realized separately. 4).
  • the connecting member 10 is restricted from moving to the base end side and the tip end side with respect to the case 8 by engaging with a protrusion 8 a provided inside the case 8.
  • the pump 11 is attached to the side wall of the housing 12 such that a pump chamber 12a is formed between the housing 12 having a bottom portion and a side wall erected on the peripheral edge of the bottom portion, and the bottom portion of the housing 12.
  • the diaphragm 13, the piezoelectric element 14 provided on the surface of the diaphragm 13 opposite to the pump chamber 12 a, the connection conductor 15 for supplying a driving voltage to the piezoelectric element 14, and the bottom of the housing 12 are formed.
  • An introduction side one-way valve 16 provided in the introduction port 12 b and a lead-out side one-way valve 17 provided in a lead-out port 12 c formed at the bottom of the housing 12 are provided.
  • the introduction side one-way valve 16 is opened when the pressure of the chemical solution in the introduction port 12b exceeds the pressure of the chemical solution in the pump chamber 12a, and allows the flow of the chemical solution from the introduction port 12b toward the pump chamber 12a.
  • the one-side valve 17 on the outlet side opens when the pressure of the chemical liquid in the pump chamber 12a exceeds the pressure of the chemical liquid in the outlet port 12c, and allows the flow of the chemical liquid from the pump chamber 12a toward the outlet port 12c.
  • the piezoelectric element 14 repeats expansion and contraction as shown in FIGS. 6 and 7 when a drive voltage from the AC power supply P is supplied.
  • the diaphragm 13 vibrates due to the expansion and contraction of the piezoelectric element 14.
  • FIG. 5 shows a state in which the drive voltage is not supplied from the AC power source P.
  • the inlet 12 b of the pump 11 communicates with the inlet side opening 10 a of the connecting member 10 as shown in FIG. 4, and the outlet 12 c of the pump 11 communicates with the outlet side opening 10 b of the connecting member 10. .
  • the chemical solution in the infusion bag B 1 is guided into the infusion set 2 through the connection portion 4 and is led out from the infusion set 2 through the lead-out portion 5.
  • control device 3 includes a control device main body 18 that is detachably attached to the chemical solution feeding unit 7 and an output device 19 that outputs a control command to the control device main body 18. ing.
  • the control device main body 18 can detect the presence or absence of bubbles in the chemical solution in the second conduit 6b, the connection terminal 21 electrically connected to the substrate 20, the battery 22 that supplies power to the substrate 20, and the second conduit 6b.
  • Air bubble sensor (detector) 23, blockage sensor (detector) 24 capable of detecting whether or not the second conduit 6 b or the chemical solution path on the downstream side is blocked, and a substrate storage unit 25 for storing the substrate 20.
  • a battery storage unit 26 that stores the battery 22 and a lid unit 27 that is detachably attached to the battery storage unit 26 are provided.
  • the substrate storage unit 25 includes a storage unit body 25a having a top plate (reference numeral omitted) arranged along the surface of the substrate 20 and a side wall (reference numeral omitted) extending from the peripheral edge of the top plate to the back surface side of the substrate 20.
  • a storage unit body 25a having a top plate (reference numeral omitted) arranged along the surface of the substrate 20 and a side wall (reference numeral omitted) extending from the peripheral edge of the top plate to the back surface side of the substrate 20.
  • substrate 20 is accommodated inside the side wall of the accommodating part main body 25a.
  • the top plate of the storage unit body 25a includes a recess (attached mechanism) 25d for fitting the chemical solution feeding unit 7, a pair of projecting pieces (conduit holding mechanism) 25b and a pair projecting from the top plate on both sides of the recess 25d. Projecting piece (conduit holding mechanism) 25c.
  • the concave portion 25d has a size capable of fitting the end portion on the lid 9 side of the chemical solution feeding portion 7. That is, the chemical solution feeding unit 7 corresponds to a mounting unit for mounting the control device 3 detachably.
  • a through hole 25e is formed in the top plate of the storage unit body 25a, and the connection terminal 21 extends from the substrate 20 to the outside of the storage unit body 25a through the through hole 25e.
  • a through hole 9 a is formed in the lid 9 of the chemical solution feeding section 7, and the connection conductor 15 of the pump 11 is opened to the outside of the lid 9 through the through hole 9 a. Then, the connecting terminal 21 (through hole 25e) and the connecting conductor 15 (through hole 9a) are located at positions where the connecting terminal 21 and the connecting conductor 15 can come into contact with each other by fitting the chemical solution feeding part 7 into the recess 25d. Have been placed.
  • the pair of projecting pieces 25b hold the first conduit 6a by sandwiching the first conduit 6a from both sides in the direction orthogonal to the axis.
  • the pair of projecting pieces 25c hold the second conductor 6b with the second conduit 6b sandwiched from both sides in the direction orthogonal to the axis.
  • the bubble sensor 23 and the blockage sensor 24 are built in the pair of protruding pieces 25c. Both sensors 23 and 24 are electrically connected to the substrate 20, respectively.
  • the bubble sensor 23 has a detector provided in each of the pair of protruding pieces 25c, and detects the presence or absence of bubbles of the chemical liquid between the two detectors.
  • the bubble sensor 23 can be constituted by, for example, an ultrasonic sensor that detects bubbles based on a difference in propagation efficiency of ultrasonic waves in a chemical solution.
  • the blockage sensor 24 has a detector provided on each of the pair of projecting pieces 25c, and detects blockage of the flow path of the chemical solution between the two detectors.
  • the blockage sensor 24 detects, for example, a change in the diameter of the second conduit 6b based on a change in the distance between the two magnetic bodies, and detects blockage of the flow path based on this change.
  • the substrate 20 has a plurality of elements and a circuit that electrically connects these elements.
  • the substrate 20 includes an element that converts DC power from the battery 22 into AC power, and a circuit that connects the element and the connection terminal 21.
  • the main control unit 28 shown in FIG. 9 is configured by elements and circuits provided on the substrate 20.
  • the infusion set 1A with a chemical solution feeding function includes the disposable infusion set 2 and the controller 3 to be reused.
  • the infusion set 2 includes a pump 11, and the control device 3 includes an output device 19 and a main control unit 28.
  • the output device 19 includes a display unit 19a for displaying a flow rate set value, an operation unit 19b for changing the flow rate set value and starting / stopping the infusion, and a flow rate set value set by the operation unit 19b.
  • An output control unit 19c that generates a corresponding command and controls the display of the display unit 19a, and a transmission unit 19d that wirelessly transmits the command generated by the output control unit 19c to the main control unit 28 are provided.
  • the main control unit 28 includes a reception unit 28a that receives a command output from the output device 19, a voltage setting unit 28b that sets a drive voltage output to the pump 11 based on the command received by the reception unit 28a, and a voltage And an output unit 28c that outputs the drive voltage set by the setting unit 28b to the pump 11 via the connection terminal 21.
  • the pump 11 can be driven so that the chemical solution is derived at the flow rate set by the output device 19.
  • the voltage setting unit 28b stops the pump 11 when bubbles are detected in the chemical solution in the conduit 6 by the bubble sensor 23 and / or when blockage of the flow path is detected by the blockage sensor 24.
  • the drive voltage is set as follows.
  • the output device 19 can be substituted by portable information communication terminals (a smart phone, a tablet, etc.).
  • the infusion set 2 includes the pump 11 for applying a force for deriving through the deriving unit 5 to the drug solution.
  • the so-called diaphragm pump having the connecting conductor 15, the piezoelectric element 14, and the diaphragm 13 is suitable for disposable because of its simple structure.
  • the control apparatus 3 should just be electrically connected with respect to the connection conductor 15 of the pump 11, and since it does not contact with a chemical
  • the infusion set 2 used for a specific patient can be disposable without being used for other patients, and infection can be reliably prevented by reusing the control device 3.
  • the pump 11 is incorporated in the path of the chemical solution in the infusion set 2 in order to apply a force directly to the chemical solution in the infusion set 2, a pump portion (outside of the flexible tube and the syringe (Compared with a conventional apparatus having a peristaltic pump unit and a pressing mechanism), the combined structure of the pump part and the infusion set can be reduced in size.
  • the pump 11 derives the chemical liquid by the vibration of the diaphragm 13 due to the expansion and contraction of the piezoelectric element 14, the time from the start of the chemical liquid discharge until the discharge flow rate is stabilized is shortened as compared with the conventional apparatus. be able to.
  • a conventional infusion pump and infusion device include a driving source and a mechanism (gear, etc.) for converting the power from the driving source into a force in the peristaltic direction or the pushing direction of the plunger. And a complicated structure. Therefore, it takes a long time to drive such a complex structure at a stable speed, and a loss in power transmission from the drive source is large.
  • the pump 11 uses the expansion and contraction of the piezoelectric element 14 as it is for the vibration of the diaphragm 13 as described above, and has a simple configuration as compared with the prior art.
  • the pump 11 is provided in the middle of the conduit 6, that is, at a position away from the connection portion 4 and the lead-out portion 5, it is possible to reduce the burden on the medical staff for avoiding contact with the drug solution.
  • the conduit 6 can be held by the first protruding piece 25b and the second protruding piece (conduit holding mechanism), the coupling state between the infusion bag B1 and the control device 3 can be reliably maintained using this holding force. Can do.
  • the pump 11 can be stopped in the event of an abnormality using the detection signals from both the sensors 23 and 24. it can.
  • medical solution feed function differs from the infusion set 1A with a chemical
  • the infusion set 1B with the medicinal solution feeding function is an infusion set 29 for guiding the medicinal solution in the infusion bag B1 to the patient, and is detachably attached to the infusion set 29 and controls the medicinal solution feeding operation by the infusion set 29. And a control device 30 for performing the operation.
  • the infusion set 29 is used to lead out the medicinal solution received from the infusion bag B1 through the needle (connection portion) 31 that can penetrate the rubber stopper B4 and the needle 31 so as to allow the acceptance of the medicinal solution in the infusion bag B1.
  • a conduit 6 for connecting the two.
  • the chemical solution feeding section 32 includes a needle holding member 33 that holds the proximal end portion of the needle 31, a pair of support plates 36 and 37 for supporting the needle holding member 33, and a needle.
  • the pump 11 is connected to the distal end portion 31 and the proximal end portion of the conduit 6, the needle holding member 33, the support plates 36 and 37, and the first case 34 and the second case 35 that store the pump 11.
  • the first case 34 has a bottom 34a and a side wall 34b erected on the bottom 34a along the outer peripheral edge of the bottom 34a.
  • the bottom portion 34 a has a long hole 34 c extending in a direction orthogonal to the axial direction of the needle 31, and the proximal end portion of the needle 31 is interposed between the first case 34 and the second case 35 through the long hole 34 c.
  • the proximal end portion of the needle 31 is connected to the introduction port 12 b of the pump 11 through the relay pipe 38.
  • the second case 35 has a bottom 35a and a side wall 35b erected on the bottom 35a along the outer peripheral edge of the bottom 35a.
  • the proximal end portion of the conduit 6 passes through the bottom portion 35 a and is introduced into the second case 35.
  • the proximal end portion of the conduit 6 is connected to the outlet 12 c of the pump 11 through the relay pipe 39.
  • the proximal end portion of the conduit 6 may be directly connected to the outlet 12c of the pump 11.
  • the needle holding member 33 includes a holding member main body 33a that surrounds the proximal end portion of the needle 31 over the entire circumference around the axis of the needle 31, and a disk that protrudes from the holding member main body 33a toward the outside in the radial direction of the needle 31.
  • Shaped flange 33b is
  • the flange 33b is sandwiched between the support plates 36 and 37.
  • the support plates 36 and 37 have long holes 36 a and 37 a formed along the longitudinal direction of the long hole 34 c of the first case 34, respectively, and the flange 33 b is connected to the support plates 36 and 37. It is sandwiched between the edges of the long holes 36a and 37a.
  • the holding member main body 33a is slidably disposed in the long holes 34c, 36a, 37a.
  • the needle 31 can move along the long holes 34c, 36a, and 37a using the flexibility of the relay pipe 38. Therefore, even when the infusion set 29 and the infusion bag B1 are relatively displaced when attaching the infusion set 29 and the port B3 of the infusion bag B1 to the control device 30 to be described later, the needle 31 moves. The positional deviation can be absorbed.
  • projecting portions 34 d and 35 c projecting outward are provided on part of the side walls 34 b of the first case 34 and the side walls 35 b of the second case 35 in the circumferential direction.
  • the pump 11 is accommodated in both cases 34 and 35 in a state of being sandwiched between the protruding portions 34d and 35c. Further, an opening A1 that opens the connection conductor 15 of the pump 11 to the outside of the cases 34 and 35 is provided between the protrusions 34d and 35c.
  • the control device 30 includes a substrate 20, a connection terminal 21, a battery 22, a substrate storage unit 40 that stores the substrate 20, a battery storage unit 41 that stores the battery 22, A feeding portion support portion 42 that supports the chemical solution feeding portion 32 between the substrate housing portion 40 and the battery housing portion 41; and a retaining portion 43 that prevents the chemical solution feeding portion 32 supported by the feeding portion support portion 42 from coming off. And a container holding mechanism 44 for holding the port B3 of the infusion bag B1.
  • the substrate storage unit 40 has a peripheral wall 40 a that surrounds the substrate 20 over the entire circumference centered on a line parallel to the axis of the needle 31.
  • a concave portion 40b is formed in a portion of the peripheral wall 40a facing the battery storage portion 41.
  • the recess 40b has a size that allows the protrusions 34d and 35c of the chemical solution feeding part 32 to be fitted.
  • a through hole 40c is formed in a part of the peripheral wall 40a constituting the recess 40b.
  • the connection terminal 21 extends from the substrate 20 to a position in the recess 40b through the through hole 40c. Therefore, the projecting portions 34d and 35c of the chemical solution feeding section 32 are fitted in the recess 40b, whereby the connection conductor 15 of the pump 11 and the connection terminal 21 of the control device 30 are electrically connected.
  • the feeding portion support portion 42 receives the chemical solution feeding portion 32 from below in a state where the protruding portions 34d and 35c are fitted in the recess 40b.
  • the retaining portion 43 is formed between the end portion of the substrate housing portion 40 and the end portion of the battery housing portion 41 so as to contact the base end surface of the chemical solution feeding portion 32 with the protruding portions 34d and 35c fitted in the recess portion 40b. It is provided in between. Further, the retaining portion 43 has a notch (reference numeral omitted) for passing the needle 31 in a state where the proximal end surface of the chemical solution feeding portion 32 is in contact.
  • the container holding mechanism 44 is provided at the end of the substrate storage unit 40 and the battery storage unit 41 opposite to the retaining portion 43.
  • the container holding mechanism 44 has a receiving portion 44a and a rotating portion 44b for sandwiching the port B3 of the infusion bag B1.
  • the receiving portion 44a receives the port B3 from below with the protruding portions 34d and 35c fitted in the recess 40b. Further, the end surface 44 c (see FIG. 11) facing the retaining portion 43 side of the receiving portion 44 a sandwiches the chemical solution feeding portion 32 with the retaining portion 43.
  • medical solution feeding part 32 of the infusion set 29 is corresponded to the mounting part for mounting
  • the substrate storage unit 40, the battery storage unit 41, the feeding unit support unit 42, the retaining unit 43, and the container holding mechanism 44 (receiving unit 44a) of the control device 30 are attached to a mounting mechanism on which the infusion set 29 is detachably mounted. Equivalent to.
  • the rotating portion 44b is rotatable with respect to the receiving portion 44a around an axis J1 (see FIG. 11) parallel to the axis of the needle 31. Further, the rotating portion 44b is urged in a direction in which the tip end portion of the rotating portion 44b approaches the receiving portion 44a by a winding spring (not shown).
  • the port B3 can be held between the receiving portion 44a and the rotating portion 44b by the urging force of the winding spring.
  • the port B3 of the infusion bag B1 can be held by the container holding mechanism 44 in a state where the infusion set 29 is attached to the control device 30.
  • the coupling state between the infusion set 29 and the control device 30 can be reliably maintained by using the holding force of the container holding mechanism 44.
  • the pump 11 has an introduction-side one-way valve 16 and a discharge-side one-side valve 17, and allows the flow of the chemical solution from the introduction port 12b toward the discharge port 12c.
  • the flow rate of the chemical solution during free flow increases as the pressure of the chemical solution in the infusion bag B1 increases.
  • the infusion set with a medicinal solution feeding function has a switching valve 47 that closes the flow path of the medicinal solution when the pressure of the medicinal solution in the infusion bag B1 is equal to or higher than a preset reference pressure. .
  • the switching valve 47 is connected to the pump 11 through the first introduction port 47a and directly connected to the infusion bag B1 through the second introduction port 47b.
  • the switching valve 47 is connected to the conduit 6 through the outlet port 47c.
  • the switching valve 47 includes an abnormal stop valve 48 connected to the first introduction port 47a and a high-pressure selection valve 46 connected to the abnormal stop valve 48 and the second introduction port 47b.
  • the high pressure selection valve 46 closes a passage (hereinafter referred to as a first passage) connected to the first introduction port 47a when the pump 11 is not operated, and opens the first passage when the pump 11 is operating. Thus, the chemical liquid discharged from the pump 11 is guided to the conduit 6.
  • the high pressure selection valve 46 includes an initial position 46a for closing a passage connected to the first passage and the second introduction port 47b (hereinafter referred to as a second passage), and the first passage with the second passage closed. Switching between the open switching position 46b is possible.
  • the high pressure selection valve 46 is biased to the initial position 46a by a differential pressure setting spring 46c.
  • the differential pressure setting spring 46c has an urging force that is set so that the high-pressure selection valve 46 is switched to the switching position 46b by a pressure corresponding to the differential pressure of the second passage relative to the first passage generated when the pump 11 is operated.
  • the abnormal stop valve 48 opens the first passage when the pressure of the chemical solution in the infusion bag B1 is less than the reference pressure, while the first stop passage when the pressure of the chemical solution in the infusion bag B1 is equal to or higher than the reference pressure. It is for closing.
  • the abnormal stop valve 48 can be switched between an initial position 48a for opening the first passage and a switching position 48b for closing the first passage.
  • the abnormal stop valve 48 is biased to the initial position 48a by the reference pressure setting spring 48c.
  • the reference pressure setting spring 48c has a biasing force that is set so that the abnormal stop valve 48 is switched to the switching position 48b when the pressure of the drug solution in the infusion bag B1 becomes the reference pressure.
  • the initial position 48a is provided with a throttle for generating back pressure. If the flow resistance in the downstream path of the abnormal stop valve 48 is sufficiently large to generate back pressure, The aperture can be omitted.
  • the abnormal stop valve 48 When the drug solution in the infusion bag B1 is less than the reference pressure, the abnormal stop valve 48 is switched (biased) to the initial position 48a. In this state, the chemical discharged from the pump 11 is guided to the conduit 6 through the abnormal stop valve 48 and the high pressure selection valve 46.
  • the abnormal stop valve 48 is switched to the switching position 48b by the pressure of the chemical solution. Thereby, a 1st channel
  • the switching valve 47 described above can be applied to an infusion set with a chemical feeding function as shown in FIG.
  • FIG. 17 although the example which applied the switching valve 47 to the chemical
  • the switching valve 47 is housed in the first case 34 and the second case 35 of the chemical solution feeding unit 32.
  • the first introduction port 47a of the switching valve 47 is connected to the outlet 12c of the pump 11 through the relay pipe I2.
  • the second introduction port 47b of the switching valve 47 is connected to the needle 31 through the relay pipe I1.
  • the outlet port 47c of the switching valve 47 is connected to the conduit 6 through the relay pipe I3.
  • the flow path can be closed by the switching valve 47 when the pressure of the chemical solution in the infusion bag B1 is equal to or higher than the reference pressure, thereby preventing unintentional derivation of the chemical solution. can do.
  • the switching valve 47 is switched to a state in which the flow path is closed by the pressure of the chemical solution, that is, a power source (for example, a power source) for operating the switching valve 47 is unnecessary. Therefore, unintentional derivation of the chemical solution can be reliably prevented even in a situation after the infusion bag B1 is connected and before the control device 30 is mounted (before power is supplied).
  • a power source for example, a power source
  • an infusion set 1C with a chemical solution feeding function includes two infusion sets 49 that are used by being connected to vial B5, one infusion set 50 that is used by being connected to syringe S, and an infusion set. And a control device 51 for controlling the feeding operation of the chemical liquids 49 and 50.
  • the vial B5 includes a chemical solution storage bottle B6, a port B7 provided at the tip of the chemical solution storage bottle, and a rubber stopper (not shown) provided in the port.
  • the bag body B2 of the infusion bag B1 described above has rigidity that can be deformed in the direction of contracting the volume in accordance with the derivation of the chemical solution. Therefore, the pressure of the chemical solution in the infusion bag B1 is maintained also by the derivation of the chemical solution.
  • the vial B5 has rigidity that maintains its shape in accordance with the derivation of the chemical solution. Therefore, the infusion set 49 to be described later has a configuration for introducing outside air into the vial B5 as the drug solution is led out from the vial B5.
  • the infusion set 49 derives the medicinal solution received from the vial B5 through the needle 52 that can penetrate the rubber stopper of the vial B5 so as to allow the acceptance of the medicinal solution in the medicinal solution storage bottle B6.
  • the derivation unit 5 for performing the treatment the chemical solution feeding unit 53 for feeding the chemical solution along the flow path from the needle 52 to the derivation unit 5, and the derivation with the chemical solution feeding unit 53 for guiding the chemical solution from the chemical solution feeding unit 53 to the derivation unit 5.
  • a conduit 6 connecting the portion 5.
  • the needle 52 has a chemical liquid passage 52a for receiving the chemical liquid in the vial B5 and an air passage (air introduction mechanism) 52b for introducing air into the vial B5.
  • One end (the upper end in FIG. 19) of the chemical liquid passage 52a and the air passage 52b has an opening communicating with the chemical liquid storage bottle B6 in a state where the needle 52 penetrates the rubber stopper of the vial B5.
  • the other ends (the lower ends in FIG. 19) of the chemical liquid passage 52 a and the air passage 52 b extend to the inside of the chemical liquid feeding portion 53.
  • the chemical liquid feeding unit 53 includes a pump 11, a chemical liquid passage forming member 54 for forming a chemical liquid path from the needle 52 to the pump 11, and an air passage forming member for forming a passage for taking air into the needle 52.
  • (Air introduction mechanism) 55 a filter (air introduction mechanism) 56 provided in the air passage formation member 55, a chemical liquid passage formation member 54, an air passage formation member 55, and a first case (container support) that houses the filter 56 Member) 57 and a second case 58.
  • the chemical liquid passage forming member 54 includes a first chemical liquid passage 54 a that connects the other end (the lower end in FIG. 19) of the chemical liquid passage 52 a of the needle 52 and the inlet 12 b of the pump 11, an outlet 12 c of the pump 11, and the conduit 6. 2nd chemical
  • a seal member is provided between the pump 11 and the chemical liquid passage forming member 54 so that the communication between the first chemical liquid passage 54a and the inlet 12b and the communication between the second chemical liquid passage 54b and the outlet 12c are realized separately. 11b is provided.
  • the air passage forming member 55 includes an air passage 55a having a first end communicating with the other end (the lower end in FIG. 19) of the air passage 52b of the needle 52 and a second end that opens in the cases 57 and 58. ing.
  • the filter 56 allows air flow and restricts liquid flow (for example, a hydrophobic filter), and is provided so as to cover the opening at the second end of the air passage 55a.
  • the chemical solution in the vial B5 is guided to the conduit 6 through the chemical solution passage 52a of the needle 52 and the chemical solution passages 54a and 54b of the chemical solution passage forming member 54.
  • air outside air
  • the air introduced into the air passage 55 a is filtered by the filter 56.
  • the first case 57 has a top plate 57a through which the needle 52 passes.
  • the surface of the top plate 57a (upper surface in FIG. 19) is formed flat and constitutes a mounting surface 57b on which the outer surface (port B7) of the rubber stopper of the vial B5 can be mounted.
  • the second case 58 is fixed to the first case 57 so as to sandwich the chemical liquid passage forming member 54, the air passage forming member 55, and the filter 56 in the axial direction of the needle 52 between the second case 58 and the first case 57.
  • control device 51 includes substrate 20, connection terminal 21, battery 22, storage box 59 that stores substrate 20 and battery 22, and protection provided on storage box 59. And a wall 60.
  • the storage box 59 can be mounted with the chemical solution feeding section 53 with the axis of the needle 52 extending in the vertical direction and the mounting surface 57b of the chemical solution feeding section 53 facing upward.
  • the storage box 59 includes a bottom plate 59a, a side plate 59d standing on the peripheral edge of the bottom plate 59a, and a top plate 59b fixed to the upper end of the side plate 59d so as to face the bottom plate 59a.
  • the substrate 20 and the battery 22 are accommodated in a room surrounded by the plates 59a, 59b, and 59d.
  • the storage box 59 includes a pair of clamping walls 59c that protrude upward from the top plate 59b. Both sandwiching walls 59c extend in the vertical direction on the top plate 59b and face each other in the horizontal direction.
  • the interval between the both clamping walls 59c is set to an interval at which the chemical solution feeding part 53 can be held in a state where the chemical solution feeding unit 53 is sandwiched. That is, in 4th Embodiment, the chemical
  • six holding walls 59c are provided to hold the three infusion sets 49 and 50.
  • the top plate 59b is provided with a through hole 59e that penetrates the top plate 59b between the sandwiching walls 59c.
  • the connection terminal 21 extends from the substrate 20 to a position between the holding walls 59c through the through hole 59e. Therefore, by attaching the chemical solution feeding part 53 between the holding walls 59c, the connection conductor 15 (see FIG. 20) of the pump 11 and the connection terminal 21 of the control device 30 are electrically connected.
  • the lower surface of the rubber stopper (port B7) of the vial B5 can be mounted on the mounting surface 57b of the chemical solution feeding section 53 with the chemical solution feeding section 53 mounted between the holding walls 59c.
  • the protective wall 60 surrounds the infusion set 49 in a direction in which the conduit 6 extends and in a state where the upper side is open.
  • the infusion set 50 has a female luer 61 for connecting to the male luer S1 of the syringe S instead of the needle 52 of the infusion set 49.
  • the syringe S has an outer cylinder S2 having a male luer S1 and a plunger S3 sliding in the outer cylinder S2. Therefore, the plunger S3 can move with respect to the outer cylinder S2 in a direction in which the chamber in which the chemical liquid is stored is reduced as the chemical liquid in the outer cylinder S2 is led out through the male luer S1.
  • the configuration for introducing air into the syringe S (the air passage 52b of the needle 52 and the air passage forming member 55) is omitted.
  • the air introduction mechanism (the air passage 52b, the air passage forming member 55) is used even when the vial B5 that maintains its shape even when the chemical solution is led out is used. Since the air can be introduced into the vial B5 by the filter 56), the pressure fluctuation of the chemical solution in the vial B5 can be suppressed.
  • the vial B5 is formed so as to be able to stand by itself, the drug solution in the vial B5 can be quickly led out to the end by arranging the rubber stopper (port B7) of the vial B5 downward.
  • the rubber plug faces downward and the rubber plug is placed on the placement surface 57b of the first case 57, so that the vial B5 is placed with the rubber stopper faced downward. Can be made independent.
  • An infusion set 1D with a medicinal solution feeding function includes an infusion set 62 for guiding the medicinal solution in the syringe S to a patient, a control device 63 that is detachably attached to the infusion set 62 and controls the medicinal solution feeding operation by the infusate set 62. It has.
  • the infusion set 62 includes a female luer 61 connected to the male luer S1 of the syringe S, a deriving unit 5 for deriving a chemical liquid received from the syringe S via the female luer 61, and a flow path from the female luer 61 to the deriving unit 5. And a conduit 6 for connecting the chemical solution feeding unit 66 and the outlet unit 5 in order to guide the chemical solution from the chemical solution feeding unit 66 to the outlet unit 5.
  • the chemical solution feeding unit 66 includes the pump 11 although not shown.
  • the control device 63 is in a state in which the control device main body 64 having the substrate 20 (not shown) and the connection terminal 21, the connection terminal 21 of the control device main body 64, and the connection conductor 15 (not shown) of the pump 11 are connected. And a syringe case (covering member) 65 for storing the chemical solution feeding section 66, the female luer 61, and the syringe S.
  • the syringe case 65 includes a case main body 65a provided with a control device main body 64 and a lid 65b capable of opening and closing the case main body 65a. As shown in FIG. 21, the chemical solution feeding section 66, the female luer 61, and the syringe S can be stored in the case main body 65a with the lid 65b opened.
  • the case body 65a is provided with a notch 65b for allowing the conduit 6 to pass therethrough.
  • the chemical solution feeder 66 is attached to the case body 65a in a state where the connection conductor 15 of the pump 11 and the connection terminal 21 are electrically connected by being inserted into the case body 65a. That is, the chemical solution feeding part 66 corresponds to the mounting part, and the case main body 65a corresponds to the mounted mechanism.
  • the syringe S can be protected by the syringe case 65, it is possible to prevent the syringe S from being damaged by an external force applied to the syringe S.
  • the pump 11 may be provided between the conduit 6 and the outlet portion 5 or may be provided in the connection portion or the outlet portion 5 itself.
  • the present invention is an infusion set for guiding a chemical solution in the chemical solution container to a patient while being connected to the chemical solution container that stores the chemical solution, and accepting the chemical solution from the chemical solution container.
  • a connecting portion connectable to a container, a deriving portion for deriving a chemical solution received from the chemical solution container via the connecting portion, and the connecting portion and the connection portion for guiding the chemical solution from the connecting portion to the deriving portion.
  • a conduit provided between the lead-out portion, a connection conductor, a piezoelectric element that repeats expansion and contraction by a driving voltage supplied via the connection conductor, and a diaphragm that vibrates due to expansion and contraction of the piezoelectric element;
  • a pump for supplying a chemical with a force for deriving through the deriving unit in response to the supply of the drive voltage, a control device for supplying the drive voltage to the pump, and And connection conductors and a mounting portion for detachably mounting the control device in a state of being electrically connected to provide an infusion set.
  • the infusion set includes a pump for giving the drug solution a force for deriving through the deriving unit.
  • a so-called diaphragm pump having a connection conductor, a piezoelectric element, and a diaphragm is suitable for disposable because of its simple structure. Moreover, since the control apparatus should just be electrically connected with respect to the connection conductor of a pump and does not contact with a chemical
  • the infusion set used for a specific patient can be discarded without being used for other patients, and infection can be reliably prevented by reusing the control device.
  • the diaphragm pump is incorporated in the path of the chemical solution in the infusion set in order to directly apply the force to the chemical solution in the infusion set, the pump part (peristaltic type) provided outside the flexible tube and the syringe Compared with a conventional device having a pump unit and a pressing mechanism), the combined structure of the pump part and the infusion set can be reduced in size.
  • the diaphragm pump derives the chemical liquid by the vibration of the diaphragm due to expansion and contraction of the piezoelectric element, it can shorten the time from the start of the chemical liquid discharge until the discharge flow rate is stabilized as compared with the conventional apparatus. it can.
  • a conventional infusion pump and infusion device include a driving source and a mechanism (gear, etc.) for converting the power from the driving source into a force in the peristaltic direction or the pushing direction of the plunger. And a complicated structure. Therefore, it takes a long time to drive such a complex structure at a stable speed, and a loss in power transmission from the drive source is large.
  • the diaphragm pump uses the expansion and contraction of the piezoelectric element as it is for vibration of the diaphragm as described above, and has a simpler structure than the conventional one.
  • the diaphragm pump has a configuration that allows the flow of the chemical liquid from the inlet side to the outlet side, for example, when an external force is applied to the chemical liquid container to increase the pressure of the chemical liquid in the chemical liquid container, There is a possibility that the chemical solution is unintentionally derived from the deriving unit.
  • the pressure of the chemical solution in the chemical solution flow path from the connection portion to the outlet portion is equal to or higher than a preset reference pressure
  • the pressure of the chemical solution It is preferable to further include a switching valve that returns to a state in which the flow path is opened when the pressure of the chemical liquid in the chemical liquid container is lower than the reference pressure.
  • the flow path can be closed by the switching valve when the pressure of the chemical solution in the chemical solution container is equal to or higher than the reference pressure, unintentional derivation of the chemical solution can be prevented.
  • the switching valve is switched to a state in which the flow path is closed by the pressure of the chemical solution, that is, a power source (for example, a power source) for operating the switching valve is unnecessary. Therefore, unintentional derivation of the chemical solution can be reliably prevented even in a situation after the chemical solution container is connected and before the control device is mounted (before power is supplied).
  • a power source for example, a power source
  • the pump can be provided at the connection part or the lead-out part, but the connection part and the lead-out part are parts that are highly likely to come into contact with the chemical solution. Therefore, when a pump is provided at the connection part or the lead-out part, the medical worker needs to handle the pump while paying close attention to avoid contact with the drug solution (for example, mounting a control member on the pump).
  • the pump is provided in the middle of the conduit.
  • the pump is provided at a position away from the connection part and the lead-out part, it is possible to reduce the burden on the medical staff for avoiding contact with the drug solution.
  • the chemical solution container has a rigidity that deforms in the direction of decreasing the volume as the chemical solution is led out through the infusion set, the pressure of the chemical solution in the chemical solution container is maintained even when the chemical solution is led out.
  • the chemical container has rigidity to maintain its shape even when the chemical solution is derived through the infusion set, the pressure of the chemical solution in the chemical solution container must be introduced unless a fluid corresponding to the volume of the derived chemical solution is introduced into the chemical solution container. Can not be maintained.
  • an air introduction mechanism for introducing air into the chemical solution container is further provided.
  • the air can be introduced into the chemical liquid container by the air introduction mechanism even when the chemical liquid container has rigidity to maintain its shape even when the chemical liquid is led out, the chemical liquid in the chemical liquid container The pressure fluctuation can be suppressed.
  • the air introduction mechanism includes an air passage formed in the connection portion so as to allow introduction of outside air into the chemical solution container, and a filter that filters outside air introduced into the air passage. It is preferable to provide.
  • the outside air introduced into the air passage can be filtered by the filter, it is possible to prevent the chemical solution in the chemical solution container from being contaminated by the contaminant contained in the outside air.
  • the chemical solution in the chemical solution container can be quickly drawn out to the end by arranging the rubber stopper of the chemical solution container downward.
  • the connecting portion has a needle for penetrating the rubber plug of the chemical solution container from the outer surface to the inner surface, and the infusion set mounts the outer surface of the rubber plug with the needle penetrating the rubber plug. It is preferable to further include a container support member having a placement surface for placement.
  • the chemical container can be made self-supporting with the rubber plug facing down. Can do.
  • the present invention is a control device mounted on the infusion set, wherein a connection terminal electrically connectable with a connection conductor of the pump, and the connection conductor and the connection terminal are electrically connected.
  • a control device comprising a mounting mechanism on which a mounting portion of the infusion set is detachably mounted in a state.
  • the control device is provided in the conduit holding mechanism capable of holding the conduit in a state in which the mounting portion of the infusion set is mounted on the mounted mechanism, and the conduit holding mechanism has an abnormality in the flow of the chemical solution in the conduit It is preferable to further include a detector capable of detecting whether or not the above has occurred.
  • conduit can be held by the conduit holding mechanism, it is possible to reliably maintain the coupling state between the infusion set and the control device using this holding force.
  • the detector is provided in the conduit holding mechanism, it is possible to take measures such as stopping the pump in the event of an abnormality using the detection signal from the detector.
  • control device further includes a container holding mechanism capable of holding a part of the chemical solution container in a state where the mounting portion of the infusion set is mounted on the mounted mechanism.
  • the chemical solution container can be held by the container holding mechanism, the coupling state between the infusion set and the control device can be reliably maintained using this holding force.
  • control device further includes a covering member capable of covering the whole of the drug solution container in a state where the mounting portion of the infusion set is mounted on the mounted mechanism.
  • the chemical liquid container can be protected by the covering member, it is possible to prevent the chemical liquid container from being damaged when an external force is applied to the chemical liquid container.
  • the present invention also provides an infusion set with a chemical solution feeding function, comprising the infusion set and the control device.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Un objectif de la présente invention vise à la fois à éviter la contamination et à réduire la taille globale des dispositifs lors de l'administration d'un médicament via une tubulure. La présente invention concerne par conséquent un ensemble de perfusion (2), comprenant : une partie de raccordement (4) qui peut être raccordée à une poche de perfusion (B1) ; une partie tubulure (5) pour acheminer via une tubulure un médicament qui est reçu de la poche de perfusion (B1) via la partie de raccordement (4) ; un conduit (6) qui est disposé entre la partie de raccordement (4) et la partie tubulure (5) pour guider le médicament de la partie de raccordement (4) à la partie tubulure (5) ; une pompe (11) comprenant des conducteurs de raccordement (15), un élément piézoélectrique (14) qui s'étend et se contracte à plusieurs reprises sous l'effet de tensions d'entraînement alimentées via les conducteurs de raccordement (15), et un diaphragme (13) qui oscille sous l'effet de l'extension et de la contraction de l'élément piézoélectrique (14), ladite pompe (11) impartissant au médicament une force pour faire s'écouler le médicament à travers la partie tubulure (5) en réponse à la fourniture des tensions d'entraînement ; et une partie administration de médicament (7) pour monter de manière amovible un dispositif de commande (3), destiné à fournir les tensions d'entraînement à la pompe (11), dans un état dans lequel le dispositif de commande (3) et les conducteurs de raccordement (15) sont électriquement raccordés.
PCT/JP2014/083798 2014-01-06 2014-12-19 Ensemble de perfusion, dispositif de commande commandant son entraînement, et ensemble de perfusion avec fonction d'administration de médicament en étant doté WO2015102078A1 (fr)

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JP2014000499A JP2015128480A (ja) 2014-01-06 2014-01-06 輸液セット及びその駆動を制御する制御装置並びにこれらを備えた薬液送り機能付き輸液セット

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WO2018060505A1 (fr) * 2016-09-29 2018-04-05 Koninklijke Philips N.V. Pompe à membrane piézoélectrique pour la perfusion de liquides
CN111110943A (zh) * 2019-12-28 2020-05-08 安徽华能医用橡胶制品股份有限公司 一种连体式医用橡胶塞

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JP6475957B2 (ja) * 2014-11-27 2019-02-27 日東電工株式会社 投薬機構
JP7178838B2 (ja) * 2018-09-11 2022-11-28 大研医器株式会社 接続部材、当該接続部材を備えたポンプ用ケーシングおよび注入装置

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