WO2015037832A1 - Dispositif capillaire comprenant un filtre interne et dispositif d'injection de fluide le comprenant - Google Patents

Dispositif capillaire comprenant un filtre interne et dispositif d'injection de fluide le comprenant Download PDF

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Publication number
WO2015037832A1
WO2015037832A1 PCT/KR2014/007421 KR2014007421W WO2015037832A1 WO 2015037832 A1 WO2015037832 A1 WO 2015037832A1 KR 2014007421 W KR2014007421 W KR 2014007421W WO 2015037832 A1 WO2015037832 A1 WO 2015037832A1
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WO
WIPO (PCT)
Prior art keywords
capillary
liquid
filter
body portion
coupling body
Prior art date
Application number
PCT/KR2014/007421
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English (en)
Korean (ko)
Inventor
김용무
Original Assignee
Kim Young Mu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kim Young Mu filed Critical Kim Young Mu
Publication of WO2015037832A1 publication Critical patent/WO2015037832A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/141—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor with capillaries for restricting fluid flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
    • A61M5/38—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body using hydrophilic or hydrophobic filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
    • A61M2005/1652—Filter with duct, e.g. filtering element incorporated in a flow line, tube, duct
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7527—General characteristics of the apparatus with filters liquophilic, hydrophilic

Definitions

  • the present invention relates to a capillary device having an internal filter, and more particularly, to effectively remove various impurities that may be contained in the liquid flowing to the capillary even after primary filtration by an external filter device provided in the liquid supply line.
  • the present invention relates to a capillary device having an internal filter which prevents the capillary from clogging or narrowing so that the flow of liquid stops or the flow rate is slowed down.
  • the present invention relates to a capillary device having an internal filter having a function of preventing foreign matter from entering the liquid by scratching the inside of the capillary device by the sharp edge of the capillary when the capillary is inserted into the capillary device. .
  • the present invention relates to an injection liquid injection device comprising a capillary device with such an internal filter.
  • the injection liquid injection device In general, patients often need to be constantly injected with injections. At this time, the injection liquid injection device is used, the injection liquid injection device includes a filter device for removing foreign matter and air contained in the injection liquid.
  • a conventional injection liquid injecting apparatus includes an injection liquid storage means such as a bottle or a pack in which an injection liquid is stored, and a flexible extension tube which is provided to extend from the injection liquid storage means and in which the injection liquid supplied from the injection liquid storage means is transferred. Equipped.
  • the extension tube is provided with an external filter device for filtering and removing foreign substances and air in the supplied injection liquid, and the terminal end of the extension tube is detachably coupled to the needle or catheter inserted into the patient's body.
  • the injection liquid stored in the injection liquid storage means is discharged and supplied in small portions to flow along the extension tube, and finally, the needle or catheter coupled to the terminal connector Through the patient's body.
  • an external filter device having a hydrophobic filter and a friend filter is provided on the path of the extension tube, and finally, the end of the extension tube connected to the external filter device controls the flow rate of the drug.
  • Capillary tube is provided. Capillaries placed inside the distal ends of extension tubes prevent excessive injection of drugs that can cause fatal damage to the patient's organs at high rates of drug injection, such as anticancer drugs or antibiotics.
  • the conventional filter device is required to adopt a plurality of filter materials to completely remove the air and solid impurities contained in the drug, which is due to the structural complexity, the assembly is complicated and the manufacturing cost increases There was this.
  • the conventional filter device employing a plurality of filter materials for the complete removal of air and solid impurities not only has a problem of slowing the flow rate of the drug to be injected into the patient at a constant rate, There was an unsatisfactory problem in terms of the effect of removal.
  • the present inventor has proposed a novel configuration of the filter device and the injection liquid injection device having the same.
  • These new devices are designed to effectively remove solid impurities such as air and glass chips in the drug. Examples of such new devices are disclosed in WO 2007/117119 A1 and Korean Patent Publication No. 10-2008-0104487.
  • the filter devices and the injection liquid injection device including the same are excellent technologies, the continuous improvement can be made like other excellent technologies.
  • a conventional external filter device may primarily filter impurities such as particles contained in a liquid such as a drug and solid particles such as precipitates newly generated in a flowing drug.
  • impurities such as particles contained in a liquid such as a drug
  • solid particles such as precipitates newly generated in a flowing drug.
  • the external filter device when the first filtered drug passes through the extension tube connected to the external filter device to the capillary tube, which controls the flow rate, impurities that may exist inside the extension tube, the external The drug may be contaminated again by the adhesive component used to bond the filter device and the extension tube, and the newly generated precipitate in the drug until reaching the capillary.
  • Such contaminated drugs may cause serious harm to the patient when injected into the human body, and the capillaries may be blocked or narrowed by impurities or sediments contained in the contaminated drugs entering the capillary tube, resulting in discontinuation of drug injection or lowering of injection volume. Problems may arise.
  • the inventors have found that at least one internal filter installed just before the liquid inlet side of the capillary inside the capillary device connected to the extension tube end, and the sharp edge of the capillary tube.
  • a sealing ring that is inserted into the capillary device after the capping, as described above, various impurities that may be included in the drug flowing into the capillary after the first filtration are removed just before the capillary inflow or blocked the occurrence of impurities.
  • the technology has been completed to prevent the drug injection interruption or the lowering of the drug injection due to capillary inflow.
  • the present invention has been made to solve the above problems, the capillary tube by impurities by effectively removing various impurities that may be included in the liquid flowing to the capillary tube even after the primary filtration by the external filter device provided in the liquid supply line It is an object of the present invention to provide a capillary device having an internal filter which prevents the blockage or narrowing of the liquid to stop the flow or slow the flow rate.
  • the present invention provides a capillary device having an internal filter having a function of preventing foreign matters from entering the liquid by scratching the inside of the capillary device by the sharp edge of the capillary when inserting the capillary into the capillary device Its purpose is.
  • an injection liquid injection device comprising a capillary device having an internal filter as described above.
  • An inlet passage having an inlet connected to a liquid supply line through which the liquid flows, and an inflow passage for flowing the liquid introduced through the inlet into an inner space of the capillary device, and in communication with the inflow passage and from the inflow passage;
  • An inlet-side housing having a hollow first engaging body portion extending toward one another;
  • An outlet passage portion having an outlet port communicating with the inner space and disposed at a position opposite to the inlet passage portion, and configured to transfer the liquid exiting from the inner space to the outside; and an outlet passage portion communicating with the outlet passage portion and from the outlet passage portion.
  • a hollow second coupling body portion extending toward the inner space, the outlet side housing having a second coupling body portion coupled to communicate with the first coupling body portion to form the inner space;
  • a capillary tube disposed on the liquid flow path in the interior space
  • At least one hydrophilic internal filter for filtering the solid impurities of the liquid introduced through the inlet and the filtered liquid into the capillary.
  • a boundary wall may be formed on an inner surface of the inflow side housing near a boundary between the inflow passage part and the first coupling body part, and the boundary wall may include the first wall.
  • a through hole may be formed that is aligned with the opening of the sealing ring located in the engaging body portion.
  • the hydrophilic internal filter is a filter installed on the boundary wall in the inflow passage, a filter provided between the boundary wall and the outer surface of the sealing ring, and the It may be at least one selected from the group consisting of a filter installed between the sealing ring inner surface and the liquid inlet side of the capillary.
  • the installation position of the hydrophilic inner filter is not limited to the above examples, and the filter may be disposed in the space between the inlet port and the capillary tube if the solid impurities of the liquid introduced through the inlet port are effectively filtered.
  • the hydrophilic internal filter can be installed and the number of installations is also adjustable.
  • the pore size of the hydrophilic internal filter may be about 30 ⁇ m to 50 ⁇ m, but the present invention is not limited thereto, and a filter having a pore having an appropriate size may be used according to the size of the solid impurities. .
  • the first coupling body of the inlet-side housing has a cylindrical first insertion portion formed stepped while extending an inner diameter from a through hole of the boundary wall, and the first It may have a cylindrical second insert formed stepped while the inner diameter is extended from the insert.
  • the second engaging body portion of the outflow side housing is guided by the second insertion portion when engaged into the first engaging body portion of the inflow side housing. At this time, the front end of the second coupling body portion does not touch the stepped portion formed between the first insertion portion and the second insertion portion and leaves a free space.
  • the outlet side housing may further include a circumferential portion facing the second coupling body portion and extending at regular intervals around the outlet passage portion. have.
  • a coupling portion of the needle or the catheter may be detachably coupled to a space between the inner surface of the circumference portion and the outer surface of the outlet passage portion.
  • the sealing ring may be composed of a substantially cylindrical body portion having an opening in the center, and a ring-shaped wing portion formed stepped while the outer diameter thereof extends from the cylindrical body portion. have.
  • the diameter of the opening of the sealing ring is formed in a tapered shape that gradually narrows toward the inside, and the outermost diameter of the opening is configured to be substantially the same as the diameter of the through hole of the boundary wall so as not to change the flow velocity of the introduced liquid.
  • the innermost diameter of the opening is configured to cover the edge of the capillary tube as much as possible so as not to block the micropath of the capillary tube, so that the pointed end of the liquid inlet side of the capillary tube can be efficiently capped.
  • the corner of the tip portion of the cylindrical body portion and the edge of the circumferential portion of the ring-shaped wing portion is rounded, so that when the capillary capped with the sealing ring is inserted into the capillary device, The end portion of the capillary device is scratched to prevent foreign matters from entering the liquid.
  • the cylindrical body portion of the sealing ring can be fitted into the first insertion portion in a fitting manner, the ring-shaped wing of the sealing ring is It may be supported by a stepped portion between the first insertion portion and the second insertion portion.
  • the ring-shaped wing portion of the sealing ring may be fitted into a space between the stepped portion and the distal end of the second coupling body portion.
  • the inlet housing and the outlet housing are each formed of a synthetic resin material, preferably ABS (Acrylonitrile Butadiene Styrene copolymer) resin, it is good to configure so as to bond by performing ultrasonic bonding to the bonding surface therebetween.
  • the sealing ring is preferably made of a silicon material so as to effectively seal the space around the capillary tube and to be fitted in close contact with the first insert.
  • the injection liquid injection device of the present invention is characterized in that it comprises a capillary device having an internal filter as described above.
  • various impurities which may be included in the liquid after the first filtration by the external filter device provided in the liquid supply line are removed immediately before the capillary inflow by the at least one internal filter installed in front of the liquid inlet side of the capillary.
  • the present invention by the sealing ring for capping the pointed end of the liquid inlet side of the capillary, the inside of the capillary device is scratched by the pointed end of the liquid inlet side of the capillary can prevent the foreign matter is generated to flow into the liquid. .
  • FIG 1 is a perspective view of a state in which the capillary device 160 having the internal filter of one embodiment of the present invention is coupled.
  • FIG 2 is an exploded perspective view of the capillary device 160 having an internal filter in one embodiment of the present invention in an exploded state.
  • FIG 3 is a longitudinal cross-sectional view of the capillary device 160 having the internal filter of one embodiment of the present invention in which the capillary device 160 provided with one hydrophilic internal filter 50 is coupled.
  • FIG. 4 is a longitudinal cross-sectional view of the capillary device 160 having the internal filter of one embodiment of the present invention in which the capillary device 160 having three hydrophilic internal filters 50, 51, and 52 are installed.
  • FIG. 5 is a longitudinal cross-sectional view of a state in which only the inlet housing 20 and the outlet housing 10 are coupled together, excluding components that are internally housed in the capillary device 160 illustrated in FIGS. 3 and 4.
  • FIG. 6 is a perspective view and a longitudinal sectional view of the sealing ring 40 embedded in the capillary device 160 with the internal filter of one embodiment of the present invention.
  • FIG. 7 is a schematic diagram illustrating an embodiment of an injection liquid injection device to which a capillary device 160 having an internal filter according to an embodiment of the present invention is applied.
  • the capillary device 160 with the internal filter of one embodiment of the invention as shown in FIGS. 1 to 4 is provided at the end of the extension tube 152 to which liquid is supplied (see FIG. 7), A needle or catheter inserted into the body is detachably coupled to the capillary device 160 having the internal filter of one embodiment of the present invention.
  • the capillary device 160 having the internal filter includes a large inlet housing 20, an outlet housing 10, a capillary tube 30, a sealing ring 40, and a hydrophilic internal filter ( 50).
  • the inlet side housing 20 has an inlet port 29 which is connected to the liquid supply line through which the liquid flows, and the liquid introduced through the inlet port 29 is capillary device ( An inflow passage 26 to flow into the inner spaces 32 and 33 of the 160, and communicates with the inflow passage 26 and extends from the inflow passage 26 toward the inner spaces 32 and 33. It is provided with a hollow first coupling body portion 27 formed. An inclined surface 262 is formed at an inlet side of the flow passage 26, and when the extension tube 152 supplied with liquid is inserted into and connected to the flow passage 26, the inclined surface 262 extends through the inclined surface 262. The end of the tube 152 is guided to facilitate insertion and removal of the extension tube.
  • a boundary wall 244 is formed on an inner surface of the inflow side housing 20 near a boundary between the inflow passage 26 and the first coupling body portion 27, and the boundary wall 244 has the first coupling body.
  • a through hole 28 is formed which is aligned with the opening 48 of the sealing ring 40 which is located in the part 27.
  • the first coupling body portion 27 has a cylindrical first insertion portion 24 formed stepwise while the inner diameter thereof is expanded from the through hole 28 of the boundary wall 244, and the inner diameter from the first insertion portion 24.
  • the expansion has a cylindrical second insertion portion 22 formed stepped.
  • the outer circumferential surface of the first coupling body portion 27 is provided with a plurality of mountain-shaped protrusions 25 extending in the longitudinal direction.
  • two mountain shaped protrusions 25 are formed on the outer circumferential surface of the first coupling body portion 27 and they are spaced apart from each other at approximately 180 °. have.
  • the outlet side housing 10 has an outlet 122 communicating with the internal spaces 32 and 33 and faces the inlet passage 26.
  • the second coupling body portion 16 couples the outlet side housing 10 to the inlet side housing 20
  • the outer surface of the second coupling body portion 16 closely fits to the inner surface of the first coupling body portion 27 to be coupled thereto. do.
  • the first coupling body portion 27 and the second coupling body portion 16, which are hollow, communicate with each other to form the internal spaces 32 and 33 (see FIG. 5).
  • the second coupling body portion 16 of the outlet side housing 10 When the second coupling body portion 16 of the outlet side housing 10 is coupled while being fitted in close contact with the first coupling body portion 27 of the inlet side housing 20, the second insertion portion 22 is coupled. Guided by and combined. In addition, the front end 162 of the second coupling body portion 16 does not touch the stepped portion 242 formed between the first insertion portion 24 and the second insertion portion 22 to leave a free space. The ring-shaped wing portion 42 of the sealing ring 40 is inserted into this clearance.
  • the outlet side housing 10 further includes a circumferential portion 14 which faces the second coupling body portion 16 and extends at regular intervals around the outlet passage portion 12.
  • a coupling portion (not shown) of the needle or the catheter may be detachably coupled to the space 142 between the inner surface of the circumference portion 14 and the outer surface of the outflow passage portion 12.
  • a plurality of protrusions 144 extending in the longitudinal direction are formed on the outer circumferential surface of the circumferential portion 14.
  • the plurality of protrusions 144 formed on the outer circumferential surface of the circumferential portion 14 and the plurality of mountain-shaped protrusions 25 formed on the outer circumferential surface of the first coupling body portion 27 described above facilitate the user's gripping. Helps to smoothly apply the user's force when rotating, dismounting and engaging the needle or catheter.
  • each of the inlet housing 20 and the outlet housing 10 is molded of a synthetic resin, preferably ABS (Acrylonitrile Butadiene Styrene copolymer) resin, and then ultrasonically bonded to the bonding surface 146 therebetween. It is good to configure to implement by combining.
  • ABS Advanced Chemical Bonding
  • the present invention is not limited thereto and that the above components may be constructed using various materials known in the art consistent with the object of the present invention.
  • the capillary tube 30 is disposed on the liquid flow path in the interior spaces 32 and 33, specifically the sealing ring 40 and the second coupling body portion. It is arranged in the space surrounded by 16. At this time, the liquid inlet side portion of the capillary tube 30 is tightly inserted into the sealing ring 40 and the liquid outlet side portion of the capillary tube 30 is inserted into the second coupling body portion 16 and accommodated therein. .
  • the accommodated capillary tube 30 can communicate with the inflow passage 26 through an opening 48 formed at one side of the sealing ring 40 while the pointed end of the liquid inlet side is capped by the sealing ring 40. Done.
  • the liquid outlet side portion of the accommodated capillary tube 30 is inserted into the second coupling body 16 so as to be in communication with the outlet passage 12 which is in communication with the second coupling body 16. do.
  • the liquid outlet side end of the capillary tube 30 is a separation prevention block 148 formed between the second coupling body portion 16 and the outlet passage portion 12 to prevent the liquid outlet side from being separated toward the outlet passage portion 12. It is supported and fixed by.
  • the sealing ring 40 has a substantially cylindrical body portion 44 having an opening 48 in the center thereof, and the outer diameter thereof extends from the cylindrical body portion 44. It is composed of a ring-shaped wing portion 42 formed stepped.
  • the diameter of the opening 48 of the sealing ring 40 is formed in a tapered shape that gradually narrows toward the inside, and the outermost diameter of the opening 48 is the through hole 28 of the boundary wall 244.
  • the inner diameter of the opening 48 does not block the micropath of the capillary tube 30 while covering the edge of the capillary tube 30 as much as possible without changing the flow velocity of the introduced liquid. It can be configured to efficiently cap the pointed end of the liquid inlet side of the capillary (30).
  • the edge of the tip portion of the cylindrical body portion 44 and the edge of the circumferential portion of the ring-shaped wing portion 42 is rounded, so that the capillary 30 capping the sealing ring 40 capillary device
  • the inside of the capillary device 16 is scratched by the pointed end of the liquid inlet side of the capillary tube 30 when inserted into the first inserting portion 24, that is, foreign matter is generated and introduced into the liquid. Can be prevented.
  • the cylindrical body portion 44 of the sealing ring 40 is fitted and coupled to the first insertion portion 24 in a fitting manner, the ring-shaped wing portion 42 of the sealing ring 40 is the first It is supported by the stepped portion 242 between the insertion portion 24 and the second insertion portion 22.
  • the ring-shaped wing portion 42 of the sealing ring 40 is fitted into the space between the stepped portion 242 and the tip 162 of the second coupling body portion 16 is coupled.
  • the liquid outlet side end of the capillary tube 30 is in communication with the outlet 122 through the outlet passage portion 12, the remaining portion of the capillary tube 30 is the sealing ring 40 and the first 2 is enclosed so as to be completely sealed by the inner wall of the engaging body portion 16 (see FIGS. 3 and 4).
  • the sealing ring 40 is preferably made of a silicon material so as to effectively seal the space around the capillary tube 30, the first inserting portion 24 and the like to be coupled and coupled.
  • the present invention is not limited thereto and that the above components may be constructed using various materials known in the art consistent with the object of the present invention.
  • a hydrophilic internal filter that filters out solid impurities of the liquid introduced through the inlet port 29 and introduces the filtered liquid into the capillary tube 30 has the inlet port 29 and the capillary tube.
  • the hydrophilic inner filter is a filter 50 (hereinafter referred to as “A filter”) installed between the boundary wall 244 and the outer surface of the sealing ring 40 and the inflow passage 26.
  • Filter 51 hereinafter referred to as "B filter”
  • filter 52 hereinafter referred to as "between" the inner surface of the sealing ring 40 and the liquid inflow side of the capillary tube 30
  • FIG. 3 shows an example in which one hydrophilic inner filter 50 is installed between the boundary wall 244 and the outer ring 40, and in FIG. 4, three hydrophilic inner filters as described above.
  • An example in which all of 50, 51, and 52 are provided is shown.
  • a B filter or a C filter may be installed alone, and may be installed as a combination of A filter and B filter, a combination of A filter and C filter, and a combination of B filter and C filter. .
  • the installation positions of the hydrophilic internal filters 50, 51, and 52 are not limited to the above examples, provided that the solid impurities of the liquid introduced through the inlet port 29 are effectively filtered.
  • the hydrophilic internal filter 50, 51, 52 can be installed in the space between the inlet 29 and the capillary 30, and the installation quantity can be adjusted.
  • the hydrophilic inner filter 50, 51, 52 removes various impurities that may be included in the flowing liquid even after primary filtration by the external filter device 150, immediately before the capillary 30 inflow.
  • the problem of interrupting liquid injection or lowering the liquid injection amount due to capillary inflow can be prevented in advance (see FIG. 7).
  • the capillary device 160 of the present invention can be applied to the injection liquid injection device 100 shown in WO 2010/120051 A2 as shown in FIG. 7.
  • gas generated from the gas supply unit 130 disposed behind the piston 140 pushes the piston 140 forward and the drug in the cylinder 110.
  • the drug stored in the storage space 120 is pushed out to the flow tube 151 at a constant flow rate by the piston 140.
  • Impurities such as solid particles and gas, such as air, contained in the drug flowing from the drug storage space 120 to the flow tube 151 are primarily by a hydrophilic filter and a hydrophobic filter provided to the external filter device 150. Removed.
  • new contaminants may exist between the external filter device 150 and the capillary device 160 even after the first filtration by the external filter device 150.
  • particles and other contaminants present in the extension tube 152, an adhesive component used to connect the external filter device 150 and the extension tube 152, the extension tube 152 and the capillary device There may be an adhesive component used to connect 160 and a precipitate depending on the nature of the drug.
  • the A filter, B filter and / or C filter provided in the capillary device 160 of the present invention as described above filters such impurities before entering the capillary 30 so that these impurities block or narrow the capillary 30. Undesirable phenomenon can be prevented in advance.
  • the hydrophilic inner filter (50, 51, 52) can be used as long as it is well known in the art and usually available as a filter to filter out the solid impurities and pass through the liquid.
  • the pore size of the hydrophilic inner filter 50, 51, 52 may be about 30 ⁇ m to 50 ⁇ m, but the present invention is not limited thereto, and a filter having a pore having an appropriate size may be used according to the size of solid impurities. Of course it can.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne un dispositif capillaire comprenant un filtre interne. Selon la présente invention, diverses impuretés, qui peuvent être contenues dans un liquide après une première filtration par un dispositif filtrant externe prévu au niveau d'une conduite d'alimentation en liquide, sont éliminées juste avant d'entrer dans un capillaire par au moins un filtre interne prévu devant le côté d'entrée de liquide du capillaire ; ainsi, une interruption pendant l'injection de liquide ou une baisse de la quantité de liquide injectée peut être prévenue par l'entrée des impuretés dans le capillaire. En outre, la présente invention peut prévenir l'entrée, dans le liquide, de matière étrangère produite lorsque l'intérieur du dispositif est gratté par l'extrémité pointue du côté d'entrée de liquide d'un capillaire, en utilisant un joint d'étanchéité pour couvrir l'extrémité pointue du côté d'entrée de liquide du capillaire.
PCT/KR2014/007421 2013-09-10 2014-08-11 Dispositif capillaire comprenant un filtre interne et dispositif d'injection de fluide le comprenant WO2015037832A1 (fr)

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KR10-2013-0108222 2013-09-10
KR1020130108222A KR101535350B1 (ko) 2013-09-10 2013-09-10 내부 필터를 구비한 모세관 장치 및 이를 구비한 주사액 주입장치

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JP2022539746A (ja) * 2019-07-05 2022-09-13 ヨンヒョン キム 薬品移送管装置用カバー及びこれを含む薬品移送管装置セット

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KR101993759B1 (ko) * 2017-09-25 2019-07-01 주식회사 유니메딕스 의료용 캐필러리의 결합구조
KR101833729B1 (ko) * 2017-10-31 2018-03-02 이정민 의료 주입장치용 주입액 여과필터
KR102085515B1 (ko) * 2018-02-27 2020-03-05 주식회사 이화메디텍 약액 공급 조절장치 및 이를 구비한 주사액 주입장치
KR102044467B1 (ko) 2018-07-27 2019-11-14 김은석 수액 세트
WO2020080889A1 (fr) * 2018-10-19 2020-04-23 Yong Hyun Kim Filtre à air pour injection de liquide médicamenteux et appareil d'injection de liquide médicamenteux associé
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