WO2014192196A8 - センサ、検出方法、検出システム、および検出装置 - Google Patents

センサ、検出方法、検出システム、および検出装置 Download PDF

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Publication number
WO2014192196A8
WO2014192196A8 PCT/JP2013/085212 JP2013085212W WO2014192196A8 WO 2014192196 A8 WO2014192196 A8 WO 2014192196A8 JP 2013085212 W JP2013085212 W JP 2013085212W WO 2014192196 A8 WO2014192196 A8 WO 2014192196A8
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WO
WIPO (PCT)
Prior art keywords
substance
detection
sensor
bond
enzyme
Prior art date
Application number
PCT/JP2013/085212
Other languages
English (en)
French (fr)
Other versions
WO2014192196A1 (ja
Inventor
浩康 田中
秀治 栗岡
信介 山東
Original Assignee
京セラ株式会社
国立大学法人九州大学
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 京セラ株式会社, 国立大学法人九州大学 filed Critical 京セラ株式会社
Priority to US14/894,894 priority Critical patent/US10942191B2/en
Priority to JP2015519610A priority patent/JP6285428B2/ja
Publication of WO2014192196A1 publication Critical patent/WO2014192196A1/ja
Publication of WO2014192196A8 publication Critical patent/WO2014192196A8/ja

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N5/00—Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid
    • G01N5/02—Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid by absorbing or adsorbing components of a material and determining change of weight of the adsorbent, e.g. determining moisture content
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Ecology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

　第１物質を高い精度で検出可能なセンサなどを提供する。検体に第１物質が含まれるか否かを検出するためのセンサ１００であって、基体１０と、基体１０の表面に第２物質２００が固定化されている検出部１３とを備え、第２物質２００は、アミノ酸と、酵素と反応して切断される結合２１０と、アミノ酸に結合２１０によって結合しており且つ他の物質に結合可能な第１の基２０２を有する第１化合物２０１とを有しており、第１物質との反応によって酵素を生成する第３物質に接触した検体が、検出部１３に導入される、センサ１００とする。
PCT/JP2013/085212 2013-05-31 2013-12-27 センサ、検出方法、検出システム、および検出装置 WO2014192196A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US14/894,894 US10942191B2 (en) 2013-05-31 2013-12-27 Sensor, detection method, detection system, and detection apparatus
JP2015519610A JP6285428B2 (ja) 2013-05-31 2013-12-27 センサ、検出方法、検出システム、および検出装置

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013115044 2013-05-31
JP2013-115044 2013-05-31

Publications (2)

Publication Number Publication Date
WO2014192196A1 WO2014192196A1 (ja) 2014-12-04
WO2014192196A8 true WO2014192196A8 (ja) 2015-12-17

Family

ID=51988252

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2013/085212 WO2014192196A1 (ja) 2013-05-31 2013-12-27 センサ、検出方法、検出システム、および検出装置

Country Status (3)

Country Link
US (1) US10942191B2 (ja)
JP (1) JP6285428B2 (ja)
WO (1) WO2014192196A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016188829A (ja) * 2015-03-30 2016-11-04 日本電波工業株式会社 感知センサー及び感知装置
US10126165B2 (en) * 2015-07-28 2018-11-13 Carrier Corporation Radiation sensors
KR102628485B1 (ko) * 2016-06-28 2024-01-24 삼성디스플레이 주식회사 증착 모니터링을 위한 수정 진동자 센서
US11815489B2 (en) 2018-10-30 2023-11-14 Kyocera Corporation Measurement device and measurement method
JP7217182B2 (ja) * 2019-03-14 2023-02-02 日本無線株式会社 弾性表面波センサ及び弾性表面波センサの製造方法
WO2020218369A1 (ja) * 2019-04-26 2020-10-29 京セラ株式会社 センサ装置の製造方法、及び、センサ装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1031830B8 (fr) 1999-02-23 2009-12-09 Asulab S.A. Système électrochimique pour la détermination d'un temps de coagulation du sang
US20030068655A1 (en) * 2001-09-12 2003-04-10 Protiveris, Inc. Microcantilever apparatus and methods for detection of enzymes
JP5276655B2 (ja) * 2007-06-01 2013-08-28 アトノミックス アクティーゼルスカブ 標的検体の検出用のナノ粒子を用いた生体表面弾性波（ｓａｗ）共振器増幅
JP5606435B2 (ja) * 2008-07-16 2014-10-15 ラジオメーター・メディカル・アー・ペー・エス トロンビン基質およびサンプル中の生体活性トロンビンのレベルを測定するためのアッセイ
US20110053285A1 (en) * 2009-08-27 2011-03-03 Samsung Electronics Co., Ltd. Sensor using mass enhancement of nanoparticles
JP5964960B2 (ja) * 2012-06-26 2016-08-03 京セラ株式会社 センサ、検出方法、及び検出システム

Also Published As

Publication number Publication date
US20160187358A1 (en) 2016-06-30
JP6285428B2 (ja) 2018-02-28
US10942191B2 (en) 2021-03-09
JPWO2014192196A1 (ja) 2017-02-23
WO2014192196A1 (ja) 2014-12-04

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