WO2014128007A1 - Dispositif de distribution à l'épreuve des enfants - Google Patents

Dispositif de distribution à l'épreuve des enfants Download PDF

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Publication number
WO2014128007A1
WO2014128007A1 PCT/EP2014/052380 EP2014052380W WO2014128007A1 WO 2014128007 A1 WO2014128007 A1 WO 2014128007A1 EP 2014052380 W EP2014052380 W EP 2014052380W WO 2014128007 A1 WO2014128007 A1 WO 2014128007A1
Authority
WO
WIPO (PCT)
Prior art keywords
housing
dispenser
actuating unit
cap
relative
Prior art date
Application number
PCT/EP2014/052380
Other languages
German (de)
English (en)
Inventor
Christoph Szymiczek
Stefan Ritsche
Original Assignee
Aptar Radolfzell Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49475773&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2014128007(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aptar Radolfzell Gmbh filed Critical Aptar Radolfzell Gmbh
Publication of WO2014128007A1 publication Critical patent/WO2014128007A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007Syringe-type or piston-type sprayers or atomisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • A61M15/0025Mouthpieces therefor with caps
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0027Means for neutralising the actuation of the sprayer ; Means for preventing access to the sprayer actuation means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001Piston pumps
    • B05B11/1004Piston pumps comprising a movable cylinder and a stationary piston
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001Piston pumps
    • B05B11/1016Piston pumps the outlet valve having a valve seat located downstream a movable valve element controlled by a pressure actuated controlling element
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1059Means for locking a pump or its actuation means in a fixed position
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1061Pump priming means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1061Pump priming means
    • B05B11/1063Air exhausted from the pump chamber being discharged into the container during priming
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B15/00Details of spraying plant or spraying apparatus not otherwise provided for; Accessories
    • B05B15/50Arrangements for cleaning; Arrangements for preventing deposits, drying-out or blockage; Arrangements for detecting improper discharge caused by the presence of foreign matter
    • B05B15/58Arrangements for cleaning; Arrangements for preventing deposits, drying-out or blockage; Arrangements for detecting improper discharge caused by the presence of foreign matter preventing deposits, drying-out or blockage by recirculating the fluid to be sprayed from upstream of the discharge opening back to the supplying means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00Closures with filling and discharging, or with discharging, devices
    • B65D47/04Closures with discharging devices other than pumps
    • B65D47/20Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • B65D47/24Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge with poppet valves or lift valves, i.e. valves opening or closing a passageway by a relative motion substantially perpendicular to the plane of the seat
    • B65D47/241Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge with poppet valves or lift valves, i.e. valves opening or closing a passageway by a relative motion substantially perpendicular to the plane of the seat the valve being opened or closed by actuating a cap-like element
    • B65D47/243Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge with poppet valves or lift valves, i.e. valves opening or closing a passageway by a relative motion substantially perpendicular to the plane of the seat the valve being opened or closed by actuating a cap-like element moving linearly, i.e. without rotational motion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D50/00Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures
    • B65D50/02Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures openable or removable by the combination of plural actions
    • B65D50/06Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures openable or removable by the combination of plural actions requiring the combination of different actions in succession
    • B65D50/061Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures openable or removable by the combination of plural actions requiring the combination of different actions in succession being disengageable from container only after rotational alignment of closure, or other means inhibiting removal of closure, with container, e.g. tortuous path type
    • B65D50/062Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures openable or removable by the combination of plural actions requiring the combination of different actions in succession being disengageable from container only after rotational alignment of closure, or other means inhibiting removal of closure, with container, e.g. tortuous path type the closure removal inhibiting means being a displaceable ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/27General characteristics of the apparatus preventing use
    • A61M2205/276General characteristics of the apparatus preventing use preventing unwanted use
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2215/00Child-proof means
    • B65D2215/04Child-proof means requiring the combination of different actions in succession

Definitions

  • the invention relates to a dispenser for dispensing pharmaceutical liquids.
  • dispensers usually have a housing with integrated or attached liquid storage, a movable relative to the housing operating unit with finger support surface which is subjected to force for the purpose of actuation manually and is operatively connected to an outlet valve or a feed pump, and via a discharge opening through which the liquid can be discharged into a surrounding atmosphere.
  • the donors described herein may, in particular, be designed as nasal dispensers intended for nasal administration of medicaments.
  • the liquids to be dispensed with generic dispensers also include liquids whose ingestion may be detrimental if not medically indicated. It is particularly problematic when, for example, out of curiosity or while playing, children use pharmaceutical dispensers and in doing so carry out and ingest liquid. Depending on the fluid, this can be associated with significant risks to the health of a child.
  • the object of the invention is to further develop generic dispenser to the effect that with a low design effort an effective child safety is achieved.
  • a dispenser for dispensing pharmaceutical liquids has a housing and a discharge opening provided for discharging the liquid in the manner mentioned.
  • a liquid storage is provided, which is fixed to the housing.
  • the actuating unit is provided, which is displaceable relative to the housing in an axial direction and having said finger support surface.
  • Such a known dispenser according to the invention according to this first variant added to the effect that the housing is arranged on the outside accessible ratchet, which is rotatable relative to the housing between a blocking rotational position and an actuating rotational position about a parallel to the axial direction of the dispenser axis of rotation , wherein it prevents the discharge of liquid in the blocking rotational position and allows the discharge of liquid in the actuating rotational position.
  • a housing is thus provided, to which the liquid reservoir designed as a separate external liquid storage can be coupled, in particular by means of a thread.
  • An actuating unit is displaced relative to the housing and in particular provided for linearly guided displacement. By depressing this actuating unit, an outlet valve can be opened or a pump device can be actuated, so that liquid is conveyed from the liquid reservoir to the discharge opening.
  • the ratchet wheel is rotatably provided on the housing and surrounds this preferably completely encircling. Depending on the rotational position of the ratchet wheel relative to the housing a liquid discharge is possible or impossible.
  • the ratchet can prevent the discharge of liquid in various ways in its blocking rotational position.
  • a comparatively complex possibility is that by turning the ratchet wheel, not the mobility of the operating unit is mechanically prevented directly, but the possibility to discharge liquid by this movement. This could for example be done by decoupling the actuator from a conveyor such as a piston pump. It could also happen that a switchable valve is provided in the dispenser, which is switched by turning the ratchet wheel.
  • a switchable valve is provided in the dispenser, which is switched by turning the ratchet wheel.
  • the ratchet wheel in the blocking rotational position mechanically limits or prevents the displacement of the actuating unit relative to the housing.
  • the ratchet wheel limits the mobility of the actuator unit at least to the extent that no relevant amount of liquid can be discharged.
  • This technical design is also advantageous because it is possible with her to provide conventional donors with minor structural changes with a child safety. This requires only the attachment of the locking ring and an additional stop on the actuating unit, which collides depending on the rotational position of the ratchet wheel in the course of the displacement relative to the housing before the success of a discharge with the ratchet wheel or a stopper portion provided thereon.
  • a design can be selected in which takes place at a complete rotation of the actuator unit relative to the housing by 360 °, the majority of this rotation in the locked state.
  • unintentional rotation of the ratchet wheel would take place with great likelihood no unlocking.
  • the angular range within which actuation is possible and thus defines the actuation rotational positions preferably less than 90 °, in particular preferably less than 45 °, so that with far more than likely probability free rotation of the ratchet wheel not to a Actuating rotary position leads.
  • the ratchet wheel prevents liquid discharge and thus is in the blocking rotational position.
  • the ratchet wheel prevents liquid discharge and thus is in the blocking rotational position.
  • the actuating rotation position is otherwise given, which makes a liquid discharge possible.
  • the respective specific embodiment depends on the angular range in which the blocking is caused in particular in a mechanical manner by colliding slinging means on the housing and the actuating unit.
  • the ratchet wheel can be additionally secured in the blocking rotational position.
  • the ratchet wheel can be additionally secured in the blocking rotational position.
  • a dispenser according to the invention has a housing, a discharge opening and an actuating unit displaceable relative to the housing for the purpose of discharging liquid in an axial direction, on which the discharge opening is provided. Furthermore, a protective cap is provided which can be attached to the actuating unit in such a way that it covers the discharge opening.
  • the protective cap has a special design.
  • the protective cap Corresponding to an external thread on the actuating unit, the protective cap has an inner cap and an outer cap, wherein a female thread corresponding to the outer thread is provided on the inner cap.
  • the inner cap and the outer cap are rotatable relative to each other and, depending on the design of the cap by axial or radial application of force to the outer cap in the direction of the inner cap can be positively coupled to then rotate together.
  • the inner cap is sufficiently far screwed onto the operating unit, that the discharge opening is sealed by the inner cap closed.
  • a discharge opening is provided, which is displaceable together with the actuating unit relative to the housing.
  • said two-part cap which coincides in its basic structure with known safety caps. It has an inner cap and an outer cap, with only the outer cap is directly accessible with attached protective cap.
  • the inner cap and the outer cap are normally rotated against each other, so that not easily the inner cap with internal thread of the actuator unit with external thread can be solved.
  • it can be made by axial or radial application of force to the outer cap a positive connection between the outer cap and inner cap, through which the two partial caps are rotatable together.
  • the protective cap can then be unscrewed from the operating unit.
  • Such a two-part cap with intended axial application of force is known, for example, from DE 102009049902 A1, the relevant disclosure of which is incorporated by reference in the present disclosure.
  • the inner cap of the protective cap can be unscrewed so far that it closes off the discharge opening movable with the actuating unit. When force applied to the cap thus no liquid can escape.
  • an inner end face of the inner cap abuts against the discharge opening in the fitted state of the inner cap and thereby closes it.
  • the inside end face may optionally have a survey that comes into abutment.
  • Increased safety can be ensured if an extension is provided on the inner cap, preferably in the region of the inside end face, which engages in the discharge opening when the protective cap is screwed onto the actuating unit. By such an extension, a reliable seal can be achieved quite reliably.
  • annular sealing surface is provided which comes when tightening the cap on the actuator in annular contact with a surface surrounding the discharge, wherein a limited by the annular sealing surface volume beyond the discharge at attached cap is a maximum of 100 ⁇ , preferably a maximum of 20 ⁇ , is.
  • annular sealing surface can be brought in an individual case more easily in a sealing position as provided on the inner cap extension.
  • the annular sealing surface sets when screwed in an annular region surrounding the discharge opening on. Liquid can then pass through the discharge opening although in an inner region within the annular sealing surface.
  • this design is appropriate.
  • this has a piston pump with a pump cylinder and a pump piston, which together define a pump chamber and by applying force to the actuator unit for the purpose of sosstechnikticianstrages while reducing a volume of the pumping chamber from a Poperelativlage to a Endrelativlage are displaced.
  • a return flow channel is provided, which connects the pumping chamber with the liquid reservoir after exceeding an intermediate relative position.
  • the said design with reflux channel is also very well suited to possibly remove after the manufacture, transport and storage of the dispenser still located in the pump chamber air from this.
  • a plurality of pump strokes can be carried out with attached cap and thus prevented remplisstechniksaustrag, in the course of which there is a backflow of the medium from the Pump chamber comes into the liquid storage.
  • the air can be gradually removed from the pump chamber, so that after subsequent removal of the cap directly not disturbed by air in the pump chamber discharge process is possible.
  • the in the simplest case provided on the inside end face of the inner cap surface which closes the discharge or the said extension or said annular sealing surface may be provided in one simple configuration of the inner cap in one piece with the other components, in particular their internal thread.
  • the inner cap has such a separate sealing element, which comes into contact with the discharge opening or with the surface surrounding the discharge opening when the protective cap is screwed on.
  • such a separate sealing element may be substantially planar, form said annular sealing surface or also form the extension on the inner end face of the inner cap.
  • the material of the sealing element is preferably of lower rigidity than the material of the inner cap, in order to apply sealingly in the region of the discharge opening or the nosepiece.
  • a dispenser according to the invention has a housing, a discharge opening and an actuating unit with a finger support surface displaceable in an axial direction relative to the housing for the purpose of discharging liquid.
  • the actuating unit is rotatable relative to the housing about an axis of rotation extending in the axial direction, wherein the actuating unit in at least one blocked blocking rotational position is not axially displaceable relative to the housing and in at least one unblocked actuation rotational position is axially displaceable relative to the housing.
  • the actuating unit in the blocking rotational position on the housing by a locking device against rotation can be locked.
  • a dispenser according to the invention according to this third variant of the invention starting from a secured state, the locking device must first be unlocked, so that subsequently a rotational movement of the actuating unit relative to the housing becomes possible. Only by this rotational movement an actuating rotary position is reached, in which the axial displacement of the actuating unit relative to the housing and thus the liquid discharge is possible. This process is difficult for children to see through.
  • the secured position in which the operating unit is locked against rotation, initially neither an axial movement nor a rotational movement is possible. Only by unlocking the condition is created to bring the actuator unit required in the actuation actuation rotational position.
  • the locking device in such a manner that the unlocking can be achieved by applying force to at least one unlocking surface of the actuating unit itself. This is preferably done in that the application of force to the unlocking surface causes a radial displacement of a locking portion of the actuating unit, whereby it comes to unlocking.
  • the arrangement of the unlocking directly on the actuator unit has the consequence that the operation for an adult is hardly associated with additional effort and yet remains difficult to see through a child.
  • the unlocking surface is provided by its arrangement on the actuator unit, together with this Be actuation unit to be axially displaceable relative to the housing.
  • the displaceability of the unlocking surface for the purpose of unlocking is preferably a radial displacement.
  • this displacement of the unlocking surface preferably also causes a radial displacement of a locking section of the actuating unit, which is arranged in the unlocked unlocking surface in such a way that it counteracts a positive displacement of the actuating unit.
  • the finger support surface, the unlocking surface and the locking portion are formed as a one-piece component.
  • this one-piece component is produced either from a uniform material or in the multi-component injection molding process from a plurality of different plastics, which may differ in particular with regard to their strength.
  • the unlocking surface which in principle could also be formed as a separate component, is in this embodiment integrally connected to the finger support surface, but against this preferably displaced by elastic deformation of the common one-piece component.
  • the unlocking surface is provided on the outside of a deformable circumferential jacket of the actuating unit, wherein preferably the locking portion is provided on the inside of this jacket.
  • Such a jacket is in particular preferably provided underneath the finger support surface of the actuating unit and arranged such that it covers the housing and in particular the portion of the housing which cooperates with the locking portion both when the dispenser is actuated and when it is not actuated.
  • the interaction of the displacement of the unlocking surface on the one hand and the displacement of the bolt spacing on the other hand can be achieved in the simplest case, that the locking portion and the unlocking surface are provided stationary to each other, so that the latch portion is displaced to the same extent and in the same direction as the unlocking surface relative to the housing.
  • An advantage is the design in which is offset on the said jacket of the locking portion relative to the unlocking surface in the circumferential direction, in particular by 60 ° to 120 °. In this way, it can be achieved that a force application of the unlocking surface or the preferably two opposing unlocking surfaces causes a radially outward deflection of the at least one locking portion radially outward. Since it is structurally simpler to provide a locking device in which a displacement of the locking portion radially outwardly causes the unlocking, such a design is considered advantageous.
  • the three mentioned variants of donors according to the invention can be designed as donors of various types, for example as donors for the oral administration of liquid or for the topical administration of liquids.
  • the embodiment of dispensers according to the invention is considered particularly expedient as a nasal dispenser for the nasal administration of fluids.
  • a dispenser preferably has a nose olive, at the distal end of the discharge opening is provided, wherein the nosepiece is preferably provided stationary to the actuating handle.
  • Dispensers according to the invention are particularly useful in the case of pharmaceutical fluids whose intake is associated with considerable danger. These include, for example, painkillers.
  • a use of a dispenser according to the invention with pharmaceutical liquids / formulations with nasal decongestants such as imidazoline is useful.
  • FIGS 1 a and 1 b a dispenser according to the first variant of
  • Fig. 7a and 7b another dispenser according to the third variant of the invention.
  • FIGS 1 a and 1 b show a dispenser according to the first variant of the invention.
  • This dispenser 100 has a housing 1 10, to which an external liquid storage 120 is coupled by means of a threaded connection 122.
  • an actuating unit 130 is provided, which has a finger support surface 132.
  • a nose olive 140 is further provided, at the distal end of which a discharge opening 142 is arranged.
  • the actuating unit 130 is basically opposite the housing 1 10 in one Axial direction 2 displaceable, wherein for the purpose of discharging liquid, a displacement of the actuating unit 130 in the direction of 2a on the housing 1 10 is required.
  • a pumping device 150 is provided, the inlet channel 152 protrudes into the liquid storage 120, wherein a provided for sucking liquid riser is not shown in the figures.
  • the outlet channel 154 of the pump device 150 is fastened to the inside of the nose olive 140.
  • the main body 158 of the pumping device 150 is fixed in position between the liquid storage 120 and the housing 1 10. By displacing the actuating unit 130 in the direction 2a, the outlet channel 154 of the pumping device 150 can be displaced, whereby liquid is conveyed to the discharge opening 142. This is achieved by means of an internal piston pump, not shown, within the pumping device 150.
  • a switchable valve device controls the discharge.
  • a blocking section 136 is provided on the actuating unit 130.
  • this blocking section 136 forms an inwardly directed thickening of a jacket-like ring 134, which is provided below the finger support surface 132.
  • This blocking portion 136 may cooperate with a ratchet wheel 160, which is rotatable about an axis of rotation 3 relative to the housing 120.
  • This ratchet wheel 160 has one with a serrated
  • the blocking ring 164 has an outer radius with respect to the axis of rotation 3 over almost the entire circumference, which is greater than the spacing of the axis of rotation Blocking portion 136 of the rotation axis 3. Only in a comparatively small angular range of about 15 ° is a recess 164a provided in the locking ring 164.
  • ratchet wheel 160 By means of the ratchet wheel 160 can thus be placed in a blocked or a released state in a simple manner, the donor.
  • FIGS 2a to 2c show dispensers according to the second variant of the invention.
  • such a dispenser has a housing 210 and an actuating unit 230 displaceable relative to it in the axial direction 2.
  • the latter in turn has a finger rest 232 and a nose olive 240, at the distal end of which a discharge opening 242 is provided.
  • the liquid storage and the pumping means are not shown in the illustrations of Fig. 2a to 2c. They are speak structurally those components that are shown in the embodiment of Fig. 1 a and 1 b.
  • a direct mechanical blocking of the actuating unit 230 is not provided.
  • a protective cap 270 is instead provided, which can be attached to a thread 244 of the nosepiece 240.
  • This protective cap 270 has an outer cap 272 and an inner cap 274 with an internal thread.
  • the inner cap 274 and the outer cap 272 in the axial direction 2 are mutually displaceable. They have a coupling mechanism 276, which, although counteracts a complete separation of the inner cap 274 and the outer cap 272, the said axial displaceability but allows.
  • the inner cap 274 and the outer cap 272 are also rotated about the rotation axis 3 against each other, so that a manual rotation of the outer cap 272 initially causes no rotation of the inner cap 274 and thus not directly unscrewing the cap 270 of the nosepiece 240 allowed.
  • the outer cap 272 must be pressed against the inner cap 274 in the direction 2a.
  • interlocking means 274a, 272a are positively joined together in the end region of the cap, so that then a common rotation of the inner cap 274 and the outer cap 272 is possible.
  • the inner cap 274 is dimensioned and sufficiently screwed onto the nose olive 240 in such a way that it is screwed on which can be seen in Fig. 2a, the discharge opening 242 with its inside end face 274b closes.
  • a survey is provided, the immediate comes to the discharge 274 to the plant. Depression of the outer cap 272 thus causes no liquid discharge.
  • FIGS. 2b and 2c are provided.
  • a circumferential ring 274d is provided, which circumferentially surrounds the discharge opening 242 when the cap 270 is attached.
  • a small amount of liquid in an intermediate region 273 between the inner cap and the ring 274 d and the discharge port 242 reach.
  • this small amount of liquid does not escape to the outside.
  • a sealing section 278 made of a different material is fastened to the inner cap 274.
  • the sealing ring 274d of the embodiment of FIG. 2b can also be brought about by a component which is separated from the inner cap 274 in order to use a material which is ideal for sealing purposes.
  • FIG. 3a to 3c show a further embodiment of a dispenser 200 according to the invention, which is identical to the embodiment of Fig. 2a in view of the operation and shape of the cap.
  • the peculiarity in the embodiment of Figures 3a to 3c is the peculiarity of the pumping device 250th
  • This pumping device is in the manner of a Together, the cylinder 252 and the piston 254 limit the majority of a pumping chamber 253.
  • the liquid flow into the pumping chamber 253 is effected through an access channel 255 in the piston 254. Between the access channel 255 and the pumping chamber
  • an inlet valve 256 is arranged, in the present case in the form of a ball valve acting as a check valve. Furthermore, the pump device 250 has an outlet valve 257, which is formed, on the one hand, by the nasal olive 240 penetrated by the discharge opening 242 and, on the other hand, by a valve pin 252a.
  • the piston cylinder 252 together with the valve pin 252a terminating at the end thereof can be displaced in the axial direction 2 relative to the housing 210 of the dispenser and with respect to the actuating unit 230.
  • this pump device 250 provides that the nose olive 240 is pressed down together with the actuating unit 230 in the direction of the arrow 2a, as is illustrated in FIG. 3b. As a result, the cylinder 252 is opposite the piston
  • a peculiarity of the pumping device 250 is that if the displacement of the cylinder 252 and the piston 254 relative to one another in the direction of a volumetric reduction of the pumping chamber 253 is sufficiently long, the pressure in the pumping chamber 253 is determined. according to the rules. This is the case as soon as the piston 254 has reached the area of two recesses 252b and thereby has lost the peripheral contact with the cylinder component 252.
  • the recesses 252b allow the liquid to pass from the pumping chamber 253 on the outside of the piston 254 past into a return flow channel 258, through which it can pass back into the liquid reservoir (not shown).
  • such a described pump device 250 with reflux option is of particular advantage.
  • an axial force is applied to the outer cap 272 relative to the inner cap 274 in the manner already mentioned.
  • the design of the pumping device 250 in such a way that, when the operating unit 230 is displaced further relative to the housing 210, the pressure in the pumping chamber 253 collapses, the actuating unit 230 can be pressed against a stop for the purpose of releasing the cap in the manner illustrated in Fig. 3c by the fully compressed spring 21 1 is formed. Since the liquid pressure in the pump chamber 253 has already collapsed in the state of FIG. 3c and since, moreover, the outlet valve is closed in the state of FIG. 3c, the cap can be removed without undesired leakage.
  • the type of pump described which provides for the pressure in the pump chamber 253 to be eliminated at the end of the pump stroke and at least partial return flow of the medium from the pump chamber 253 into the fluid reservoir, is also advantageous because it makes priming possible.
  • air from the pump chamber which has accumulated here, for example, during prolonged storage or during the manufacture of the dispenser, can escape into the liquid store, so that a complete dispensing operation is possible immediately after the cap has been released.
  • Fig. 4 shows a section through a two-part cap, which can be used as an alternative to the caps of Fig. 2a to 2c and 3a to 3c in one of these donors use.
  • the peculiarity of the schematically illustrated in Fig. 4 cap which coincides in terms of the basic shape of the inner cap 274 and the outer cap 272 with the caps of Figures 2a to 3c, lies in the fact that the positive connection between the caps produced not by axial but by radial application of force becomes.
  • the outer cap 272 and the inner cap 274 have teeth 272d, 274d facing each other. With undeformed outer cap 272, these teeth 272d, 274d are not in engagement with each other, so that a release of the cap is not possible. Only by a radial application of force to the outer cap 274, which is illustrated by the arrows 4, the teeth 272 d, 274 d engage such that a common rotation of the outer cap 272 and the inner cap 274 is possible.
  • the teeth 272d, 274d are shaped in such a way that they have bevels 272e, 274e which abut each other when the cap with deformed outer cap 274 is unscrewed and, due to their shape, render the teeth sliding against each other more likely. It is therefore for unscrewing the cap a particularly strong application of force in the manner indicated by the arrows 4. Since each opposite to the bevels 272e, 274e approximately radially aligned edges 272f, 274f are provided, which are intended to rest when screwing the cap together this requires a much lower radial force application.
  • FIGS. 5a to 5d show the third variant of the invention.
  • the actuating unit 330 is basically rotatable about the axis of rotation 3 relative to the housing 310. In a blocking rotational position, which is shown in FIGS. 5a and 5b, however, a depression of the actuating unit 330 in the direction 2a is not possible since a blocking web 312 is attached to the housing 310. As can be seen in particular with reference to FIG. 5b, this blocking web 312, together with a corresponding blocking section 336 of the actuating unit 330, prevents the depression of the actuating unit 330 and thus the discharge of the liquid.
  • two locking webs 314 are provided on both sides of the blocking web 312. These extend in the radial direction less far outward than the blocking rib 312. However, they extend with respect to the axial direction 2 further than the blocking rib 312 in the direction 2b and thus initially prevent the rotation of the actuating unit 330 about the axis of rotation. 3
  • the user presses on two unlocking surfaces 338 of a circumferential jacket 334 of the actuating unit 330 in the radial direction 4.
  • the jacket 334 thereby deforms into an oval shape, wherein the tion arranged offset by 90 ° blocker portion 336 in the direction of the arrow 6 is moved radially outward.
  • Figs. 5c and 5d show the state of the dispenser 300 after this twisting.
  • the blocking section 336 is now offset in the circumferential direction with respect to the blocking web 312 and with respect to the locking webs 314.
  • the actuating unit 330 can now be pressed down in the direction of the arrow 2a and thus a liquid discharge be effected.
  • the dispenser 300 can again be brought into the locked state 5a and 5b.
  • the locking webs 314 are preferably formed like a ramp, so that starting from the state of Fig. 5c and 5d, a transfer to the state of Figs. 5a and 5b is possible solely by rotating the actuator 330 relative to the housing 310, without it requires a force application of the unlocking surfaces.
  • FIGS. 3a to 3c show an alternative embodiment of a dispenser according to the third variant of the invention.
  • the pumping device 350 of this dispenser is configured in the same way as in the dispenser according to FIGS. 3a to 3c.
  • FIGS. 6 a to 6 e it is provided in the dispenser of FIGS. 6 a to 6 e that, starting from the initial position, which is illustrated in FIGS. 6 a and 6 b, a discharge process is only possible when the actuation unit 330 is opposite the Housing 310 has been rotated about the axis of rotation 3. Such a rotation about the turning Axis 3 is sufficiently possible, however, only if previously unlocking has taken place.
  • a blocking section 336 provided on a jacket 334 of the actuating unit 330 is arranged beyond a locking web 314 which is provided on the outside of the housing 310. Based on the representation of FIG.
  • a rotational movement of the actuating unit 330 relative to the housing 310 in the clockwise direction is limited thereby.
  • a rotational movement is prevented by subsequently described attacks.
  • it could also be a second in the circumferential direction relative to the first locking web 314 spaced second locking web 314 provided for this purpose.
  • an actuation ie a displacement of the actuation unit 330 in the direction of the arrow 2a relative to the housing 310, by means of radially outwardly pointing webs 335a on an inner tube 335 of the actuation unit 330 shown in FIG prevented, which rest on a circumferential, but non-continuous, blocking ridge 316 of the housing 310.
  • Stops 316a which have already been mentioned and which, starting from the locked position of FIG. 6a, prevent a rotational movement of the actuating unit 330 relative to the housing 310 in the counterclockwise direction, are also provided on this blocking ridge 316.
  • FIGS. 7a and 7b show a further embodiment of a dispenser, of which only the housing 310 and the actuation unit 330 together with the nosepiece 340 are shown in the illustrations. All other components are substantially identical to those components of the dispenser of Figs. 6a to 6e.
  • the peculiarity of this embodiment of FIGS. 7 a and 7 b is that the unlocking that is required before the actuator unit 330 can be rotated relative to the housing 310 can not be released by radially compressing the jacket 334.
  • the locking is effected in the embodiment of Fig. 7a and 7b by the inside of the jacket 334 provided webs 337 which abut in the unactuated rest position of the dispenser to an annular stop 313 of the housing.
  • a locking cam 313 a is further attached, which counteracts the rotation of the actuator unit 330 relative to the housing 310.
  • the position of the web 337 in the locking position is illustrated in Fig. 7a by dotted lines.
  • the actuator unit 330 In order to achieve unlocking, the actuator unit 330 must be displaced slightly axially in the direction of the arrow 2a relative to the housing 310, with the associated mobility first being limited to a very small distance, preferably less than 2 mm. Only if, according to the dashed representation of the web 337, this unlocking stroke is provided. has been taken, the web 337 can be displaced in the direction of arrow 7 in Fig. 7a, so that in an analogous manner as in Fig. 6d and 6e illustrates the actuator 330 and the housing 310 can be rotated against each other until the discharge stroke is possible , Unlocking is facilitated by a bevel provided on the locking cam 313a.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)

Abstract

L'invention concerne différentes variantes pour protéger des distributeurs connus pour la distribution de liquides pharmaceutiques contre l'utilisation par des enfants. Ces variantes comprennent une roue de blocage disposée de manière rotative sur le boîtier, qui empêche en particulier mécaniquement l'actionnement du distributeur, en outre des capuchons particuliers à l'épreuve des enfants qui ferment eux-mêmes directement l'ouverture de sortie ainsi que des verrouillages particuliers d'une unité d'actionnement pour empêcher l'aptitude à la rotation par rapport au boîtier nécessaire pour l'actionnement.
PCT/EP2014/052380 2013-02-22 2014-02-06 Dispositif de distribution à l'épreuve des enfants WO2014128007A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102013202933.0 2013-02-22
DE201310202933 DE102013202933B3 (de) 2013-02-22 2013-02-22 Kindergesicherte Austragvorrichtung

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WO2014128007A1 true WO2014128007A1 (fr) 2014-08-28

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PCT/EP2014/052380 WO2014128007A1 (fr) 2013-02-22 2014-02-06 Dispositif de distribution à l'épreuve des enfants

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AR (1) AR094765A1 (fr)
DE (1) DE102013202933B3 (fr)
WO (1) WO2014128007A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190035823A (ko) * 2016-08-25 2019-04-03 발리도즈, 아이엔씨. 제어된 의료 요법을 위한 시스템 및 방법
US10752412B1 (en) 2019-11-06 2020-08-25 Berlin Packaging, Llc Child resistant container with pump actuator
USD920805S1 (en) 2019-05-30 2021-06-01 Berlin Packaging, Llc Container with pump actuator
CN113086403A (zh) * 2021-04-30 2021-07-09 上海宝柏新材料股份有限公司 一种瓶嘴

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3093074B1 (fr) * 2015-05-13 2019-12-04 Aptar Radolfzell GmbH Tête distributrice pour un distributeur pour la sortie d'un liquide et distributeur doté d'une telle tête distributrice et section de fixation pour une telle tête distributrice
EP3135599B1 (fr) 2015-08-24 2018-10-03 Aptar Radolfzell GmbH Tete distributrice pour un distributeur de liquide et distributeur de liquide

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FR1542927A (fr) * 1966-11-25 1968-10-18 Aerosol Inventions Dev Capuchon de commande de sécurité pour distributeurs de petit format
EP0098939A2 (fr) * 1982-07-10 1984-01-25 Ing. Erich Pfeiffer GmbH & Co. KG Atomiseur ou pompe de dosage
US4773567A (en) * 1986-04-21 1988-09-27 Stoody William R Child resistant latching actuator for aerosol/pump valve
US6186364B1 (en) * 1999-11-22 2001-02-13 Calmar Inc. Dosage control for dispenser with child-resistant feature
EP1125864A2 (fr) * 2000-02-19 2001-08-22 Ing. Erich Pfeiffer GmbH Distributeur pour milieux
US20050173459A1 (en) * 2003-04-09 2005-08-11 Ursapharm Arzneimittel Gmbh & Co. Kg Fluid dispenser
US20060113329A1 (en) * 2004-11-29 2006-06-01 Seaquisperfect Dispensing Foreign, Inc. Dispenser with lock
FR2898818A1 (fr) * 2006-03-22 2007-09-28 Valois Sas Pompe de distribution de produit fluide
US20090266845A1 (en) * 2008-04-25 2009-10-29 Valois Sas Fluid dispenser device
DE102009049902A1 (de) 2009-10-13 2011-04-14 Ing. Erich Pfeiffer Gmbh Austragvorrichtung
US20110094990A1 (en) * 2009-10-27 2011-04-28 Drug Plastics & Glass Company, Inc. Child Resistant Closure

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DE29601047U1 (de) * 1995-02-09 1996-06-13 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für fließfähige Medien, insbesondere für den Austrag in nur einem Hub
DE19613185A1 (de) * 1996-04-02 1997-10-09 Pfeiffer Erich Gmbh & Co Kg Dosiereinrichtung für strömungsfähige Medien wie Pulver/Luft-Dispersionen

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1542927A (fr) * 1966-11-25 1968-10-18 Aerosol Inventions Dev Capuchon de commande de sécurité pour distributeurs de petit format
EP0098939A2 (fr) * 1982-07-10 1984-01-25 Ing. Erich Pfeiffer GmbH & Co. KG Atomiseur ou pompe de dosage
US4773567A (en) * 1986-04-21 1988-09-27 Stoody William R Child resistant latching actuator for aerosol/pump valve
US6186364B1 (en) * 1999-11-22 2001-02-13 Calmar Inc. Dosage control for dispenser with child-resistant feature
EP1125864A2 (fr) * 2000-02-19 2001-08-22 Ing. Erich Pfeiffer GmbH Distributeur pour milieux
US20050173459A1 (en) * 2003-04-09 2005-08-11 Ursapharm Arzneimittel Gmbh & Co. Kg Fluid dispenser
US20060113329A1 (en) * 2004-11-29 2006-06-01 Seaquisperfect Dispensing Foreign, Inc. Dispenser with lock
FR2898818A1 (fr) * 2006-03-22 2007-09-28 Valois Sas Pompe de distribution de produit fluide
US20090266845A1 (en) * 2008-04-25 2009-10-29 Valois Sas Fluid dispenser device
DE102009049902A1 (de) 2009-10-13 2011-04-14 Ing. Erich Pfeiffer Gmbh Austragvorrichtung
US20110094990A1 (en) * 2009-10-27 2011-04-28 Drug Plastics & Glass Company, Inc. Child Resistant Closure

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190035823A (ko) * 2016-08-25 2019-04-03 발리도즈, 아이엔씨. 제어된 의료 요법을 위한 시스템 및 방법
KR102483049B1 (ko) 2016-08-25 2022-12-29 발리도즈, 아이엔씨. 제어된 의료 요법을 위한 시스템 및 방법
USD920805S1 (en) 2019-05-30 2021-06-01 Berlin Packaging, Llc Container with pump actuator
US10752412B1 (en) 2019-11-06 2020-08-25 Berlin Packaging, Llc Child resistant container with pump actuator
CN113086403A (zh) * 2021-04-30 2021-07-09 上海宝柏新材料股份有限公司 一种瓶嘴
CN113086403B (zh) * 2021-04-30 2024-03-22 上海宝柏新材料股份有限公司 一种瓶嘴

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AR094765A1 (es) 2015-08-26
DE102013202933B3 (de) 2013-11-14

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