WO2014109012A1 - Instrument pour administration de liquide - Google Patents

Instrument pour administration de liquide Download PDF

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Publication number
WO2014109012A1
WO2014109012A1 PCT/JP2013/050190 JP2013050190W WO2014109012A1 WO 2014109012 A1 WO2014109012 A1 WO 2014109012A1 JP 2013050190 W JP2013050190 W JP 2013050190W WO 2014109012 A1 WO2014109012 A1 WO 2014109012A1
Authority
WO
WIPO (PCT)
Prior art keywords
liquid
cover member
state
administration device
display unit
Prior art date
Application number
PCT/JP2013/050190
Other languages
English (en)
Japanese (ja)
Inventor
正臣 今井
滋晃 冨家
学 有延
俊明 高木
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Priority to PCT/JP2013/050190 priority Critical patent/WO2014109012A1/fr
Publication of WO2014109012A1 publication Critical patent/WO2014109012A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3271—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel with guiding tracks for controlled sliding of needle protective sleeve from needle exposing to needle covering position
    • A61M5/3272—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel with guiding tracks for controlled sliding of needle protective sleeve from needle exposing to needle covering position having projections following labyrinth paths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2026—Semi-automatic, e.g. user activated piston is assisted by additional source of energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
    • A61M2005/2474—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with movable piercing means, e.g. ampoule remains fixed or steady
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion

Definitions

  • the present invention relates to a liquid administration device.
  • the prefilled syringe described in Patent Document 1 is provided with a syringe outer cylinder having a mouth part for discharging a chemical solution, a needle tube provided at the mouth part of the syringe outer cylinder and having a sharp needle tip at the tip, and a slide inside the syringe outer cylinder.
  • a movable gasket, a drug solution filled in a space surrounded by the syringe outer cylinder and the gasket, and a proximal end side of the gasket are connected, and the gasket is pressed toward the distal end to discharge the drug solution from the mouth.
  • a plunger to be operated.
  • the needle tube When administering a drug solution using a prefilled syringe, the needle tube is punctured into the living body, and the plunger is pressed in this punctured state. Thereby, a chemical
  • the prefilled syringe described in Patent Document 1 further has a visual display unit that visually notifies the completion of the administration of the liquid preparation.
  • This visible display part is comprised by the display window provided in the outer peripheral surface of the prefilled syringe, and the scale displayed on this display window, and alert
  • An object of the present invention is to provide a liquid administration device that can reliably notify completion of liquid administration.
  • the present invention has a bottom at the distal end, an opening at the proximal end, an inner cylinder that can be filled with liquid, and a sharp needle tip attached to the distal end of the inner cylinder,
  • An inner structure comprising a needle tube whose base end can communicate with the inside of the inner cylinder, and a gasket that is installed in the inner cylinder and that can slide along the axial direction of the inner cylinder;
  • An operation member that has a pusher that presses the gasket, moves the pusher in a distal direction, and performs a push operation for discharging the liquid filled in the inner cylinder from the needle tube;
  • a liquid administration device comprising: a notification mechanism having a vibration generating unit that notifies the completion state by generating a sound or vibration when the discharge of the liquid is completed by the pressing operation.
  • the vibration generating portion is provided in the first engagement portion provided in the inner structure and the operation member, and when the discharge of the liquid is completed, the first engagement portion is provided. It is preferable to have a second engaging portion that generates the sound or vibration by overcoming the engaging portion.
  • the first engagement portion is constituted by a protruding piece protruding inward from the opening, and the second engagement portion is in the middle of the longitudinal direction of the pusher, It is preferable that the outer diameter is constituted by an enlarged diameter portion.
  • At least one of the protruding piece and the enlarged diameter portion has elasticity.
  • the needle tip is provided on the outer peripheral side of the inner cylinder, covers at least the needle tip of the needle tube, and retracts from the first position in the proximal direction, and the needle tip And a cover member movable to a second position where the
  • the notification mechanism further includes a visual recognition unit that visually notifies at least the second state of the first state in which the liquid is not yet discharged and the second state in which the liquid is discharged. It is preferable.
  • the visual recognition unit includes a third state in which the cover member is located at the second position, and the inner tube and the needle tube communicate with each other, and the cover member includes the second member. It is preferable to further visually notify the fourth state in which the position has returned to the first position again.
  • the inner structure has a cylindrical outer cylinder provided between the inner cylinder and the cover member,
  • the visual recognition portion is provided on the cover member, and a cover member side window portion that can visually recognize the inside of the cover member;
  • a first display portion provided on the outer cylinder, visually recognized through the cover side window portion, and displaying the first state;
  • a second display part provided on the outer cylinder, visually recognized through the cover side window part, and displaying the second state;
  • a third display unit provided on the outer cylinder, visible through the cover side window, and displaying the third state;
  • the first display unit, the second display unit, the third display unit, and the fourth display unit are the first display unit and the third display unit. It is preferable that the part, the second display part, and the fourth display part are viewed in this order through the cover member side window part.
  • the cover member has a cylindrical shape
  • the outer cylinder is configured to be relatively movable in the axial direction of the cover member with respect to the cover member, and is configured to be relatively rotatable about the axis with respect to the cover member, By the pressing operation, the outer cylinder moves relative to the cover member in the axial direction, or the outer cylinder rotates relative to the cover member around the axis, It is preferable that the first display unit, the second display unit, the third display unit, and the fourth display unit that are visually recognized through the cover member side window unit are switched.
  • the first display portion is an outer cylinder side window portion configured to be able to visually recognize the liquid filled in the inner cylinder.
  • the second display unit, the third display unit, and the fourth display unit are configured by markers having different conditions of at least one of color and shape. Is preferred.
  • the operation member is disposed on the outer peripheral side of the cover member, and is provided with a grip portion that is connected to the pusher and is gripped when the operation member is operated. It is preferable that the grip portion has an operation member side window portion that can visually recognize the second display portion, the third display portion, and the fourth display portion.
  • an auxiliary mechanism that generates an auxiliary force for pressing the gasket through the operation member; It is preferable to further include an auxiliary force transmission prevention mechanism that prevents the auxiliary force from being transmitted to the gasket during the pressing operation.
  • the notification mechanism has at least the second state of a first state where the liquid is not yet discharged and a second state where the liquid is discharged. It further comprises a visual recognition part that notifies by visual recognition, In the blocking state in which the auxiliary force is prevented from being transmitted to the gasket, it is preferable that the visual recognition unit notifies the second state.
  • the vibration generating unit also serves as notification of completion of the operation of the auxiliary mechanism.
  • the completion state is notified to the user by generating sound or vibration.
  • the user can recognize that the discharge of the liquid has been completed, and can reliably prevent the needle tube from being removed from the living body in a state where the administration has not been completed. Therefore, it is possible to reliably prevent the amount of liquid administered to the user from becoming insufficient. Therefore, a sufficient amount of liquid can be reliably administered to the living body.
  • auxiliary mechanism that generates an auxiliary force that presses the gasket through the pusher
  • a user with weak force to press an operation member such as an elderly person or a woman, a finger of a rheumatic patient, etc.
  • the liquid when there is an auxiliary force transmission blocking mechanism that prevents the auxiliary force from being transmitted to the gasket, the liquid is prevented from being discharged from the tip of the needle tube when the liquid administration is temporarily interrupted. can do. Thereby, it is possible to prevent the liquid from being wasted or insufficient, and a sufficient amount of the liquid can be reliably administered to the living body.
  • FIG. 1 is a side view showing a first embodiment of the liquid administration device of the present invention.
  • FIG. 2 is a longitudinal sectional view of the liquid administration device shown in FIG.
  • FIG. 3 is a perspective view of the proximal end member of the outer cylinder of the cylinder of the liquid administration device shown in FIG.
  • FIG. 4 is a perspective view of the distal end side member of the outer cylinder of the cylinder of the liquid administration device shown in FIG.
  • FIG. 5 is a perspective view of a cover member of the liquid administration device shown in FIG.
  • FIG. 6 is a side view sequentially illustrating an operating state when the liquid administration device shown in FIG. 1 is used.
  • FIG. 7 is a longitudinal sectional view for sequentially illustrating the operating state when the liquid administration device shown in FIG. 1 is used.
  • FIG. 1 is a side view showing a first embodiment of the liquid administration device of the present invention.
  • FIG. 2 is a longitudinal sectional view of the liquid administration device shown in FIG.
  • FIG. 3 is
  • FIG. 8 is a side view sequentially illustrating an operating state when the liquid administration device shown in FIG. 1 is used.
  • FIG. 9 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device shown in FIG. 1 is used.
  • FIG. 10 is a side view sequentially illustrating an operating state when the liquid administration device shown in FIG. 1 is used.
  • FIG. 11 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device shown in FIG. 1 is used.
  • FIG. 12 is a side view sequentially illustrating an operating state when the liquid administration device shown in FIG. 1 is used.
  • FIG. 13 is a longitudinal sectional view for sequentially illustrating the operating state when the liquid administration device shown in FIG. 1 is used.
  • FIG. 14 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device shown in FIG. 1 is used.
  • FIG. 15 is a longitudinal cross-sectional view sequentially showing the operating state when the liquid administration device shown in FIG. 1 is used.
  • 16 is a view of the liquid administration device shown in FIG. 1 as viewed from the direction of arrow A in FIG. 17 is a view of the liquid administration device shown in FIG. 6 as viewed from the direction of arrow B in FIG. 18 is a view of the liquid administration device shown in FIG. 8 as viewed from the direction of arrow C in FIG. 19 is a view of the liquid administration device shown in FIG. 10 as viewed from the direction of arrow D in FIG. 20 is a view of the liquid administration device shown in FIG.
  • FIG. 12 as seen from the direction of arrow E in FIG. 21 is a view of the liquid administration device shown in FIG. 15 as viewed from the direction of arrow F in FIG.
  • FIG. 22 is a perspective view of a vibration generating unit of the second embodiment of the liquid administration device of the present invention.
  • FIG. 23 is a longitudinal sectional view sequentially illustrating the operating states of the third embodiment of the liquid administration device of the present invention.
  • FIG. 24 is a longitudinal cross-sectional view sequentially illustrating the operating state of the third embodiment of the liquid administration device of the present invention.
  • liquid administration device of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.
  • FIG. 1 is a side view showing a first embodiment of the liquid administration device of the present invention.
  • FIG. 2 is a longitudinal sectional view of the liquid administration device shown in FIG.
  • FIG. 3 is a perspective view of the proximal end member of the outer cylinder of the cylinder of the liquid administration device shown in FIG.
  • FIG. 4 is a perspective view of the distal end side member of the outer cylinder of the cylinder of the liquid administration device shown in FIG.
  • FIG. 5 is a perspective view of a cover member of the liquid administration device shown in FIG. 6, FIG. 8, FIG. 10, and FIG. 12 are side views sequentially showing the operating state when the liquid administration device shown in FIG. 1 is used. 7, FIG. 9, FIG. 11, and FIGS.
  • 13 to 15 are longitudinal sectional views sequentially showing the operating state when the liquid administration device shown in FIG. 1 is used.
  • 16 is a view of the liquid administration device shown in FIG. 1 as viewed from the direction of arrow A in FIG. 17 is a view of the liquid administration device shown in FIG. 6 as viewed from the direction of arrow B in FIG. 18 is a view of the liquid administration device shown in FIG. 8 as viewed from the direction of arrow C in FIG. 19 is a view of the liquid administration device shown in FIG. 10 as viewed from the direction of arrow D in FIG. 20 is a view of the liquid administration device shown in FIG. 12 as seen from the direction of arrow E in FIG. 21 is a view of the liquid administration device shown in FIG.
  • the upper side in FIGS. 1 to 21 is “base end (rear end)” or “upper (upper)”, the lower side is “tip” or “lower (lower)”, and the vertical direction is “axial direction”. "Or" longitudinal direction ".
  • the liquid administration device 10 shown in FIGS. 1, 2, and 6 to 21 is a medical device used when a liquid is administered (injected) into a living body.
  • the liquid is appropriately selected according to the purpose of use.
  • hematopoietic agents, vaccines, hormone preparations, anti-rheumatic agents, anti-cancer agents, anesthetics, anticoagulants, etc. are mainly injected subcutaneously. Chemicals.
  • the liquid administration device 10 includes an inner structure 1, an operation member 5, a cover member 6 disposed on the outer peripheral side of the inner structure 1, and a first bias that biases the cover member 6 toward the distal direction.
  • a notification mechanism 9 that notifies the completion state, an auxiliary mechanism 40, and an auxiliary force transmission blocking mechanism 50 are provided.
  • the inner structure 1 includes a cylindrical body 2 constituted by an inner cylinder 3 and an outer cylinder 4, a puncture needle 7 constituted by a double-ended needle (needle tube) 71 and a support member 72,
  • the gasket 8 is installed in the inner cylinder 3 (cylinder 2) and can slide along an axis 60 which is the central axis of the liquid administration device 10.
  • the inner cylinder 3 has an inner cylinder body 31.
  • the inner cylinder main body 31 is composed of a bottom portion 32 at a distal end portion, a side wall 33 standing from an edge of the bottom portion 32, and a member having an opening portion at a proximal end portion, that is, a member having a bottomed cylindrical shape.
  • the inner cylinder 3 can be filled with liquid.
  • the front end portion of the inner cylinder main body 31, that is, the central portion of the bottom portion 32 is integrally formed with a mouth portion 34 that is reduced in diameter relative to the portion of the side wall 33 of the inner cylinder main body 31 and through which the liquid passes. Yes. From the mouth portion 34, liquid is sucked or discharged.
  • the inner cylinder 3 includes a sealing member 11 that seals the mouth 34 of the inner cylinder main body 31 in a liquid-tight manner, and a fixing member 12 that fixes the sealing member 11 from the front end side.
  • the sealing member 11 is formed of an elastic piece, and a convex portion is formed on the base end surface thereof, and the convex portion is fitted in the mouth portion 34 in a liquid-tight manner. In this way, the sealing member 11 is mounted on the mouth portion 34 of the inner cylinder main body 31 and the mouth portion 34 is sealed in a liquid-tight manner.
  • the fixing member 12 is a cylindrical member.
  • the fixing member 12 is fitted or fused to the sealing member 11 and the mouth portion 34 from the outer peripheral side, and fixes the sealing member 11 to the inner cylinder main body 31. Thereby, the detachment
  • a fixing method of the fixing member 12 a method by adhesion or a method by welding may be used.
  • the inner cylinder main body 31 is comprised by the substantially transparent material of the said material so that the inside can be visually
  • polyvinyl chloride polyethylene, polypropylene, cyclic polyolefin, Polystyrene such as polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate, polyethylene naphthalate, butadiene-styrene copolymer, polyamide (for example, nylon) 6, various types of resins such as nylon 6,6, nylon 6,10, nylon 12), among which, such as polypropylene, cyclic polyolefin, polyester, poly- (4-methylpentene-1), and polycarbonate Tree that is easy to form It is preferred.
  • the inner cylinder main body 31 is comprised by the substantially transparent material of the said material so that the inside can be visually
  • the elastic material constituting the sealing member 11 and the gasket 8 is not particularly limited.
  • various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber
  • elastic materials such as various thermoplastic elastomers such as polyurethane, polyester, polyamide, olefin, and styrene, and mixtures thereof.
  • the outer cylinder 4 is disposed concentrically with the inner cylinder 3 on the outer peripheral side of the inner cylinder 3. As shown in FIGS. 2 to 4, the outer cylinder 4 has an overall shape of a cylinder with both ends opened, and its length is longer than that of the inner cylinder 3.
  • the inner cylinder 3 is installed inside the outer cylinder 4.
  • the outer cylinder 4 is rotatable with respect to the inner cylinder 3 about its axis.
  • the outer cylinder 4 is disposed on the proximal end side, and is configured by a proximal end side member 4a shown in FIG. 3 and a distal end side member 4b shown in FIG.
  • a pair of hole portions 41b disposed so as to face each other is formed at the base end portion of the distal end side member 4b.
  • a pair of arm portions 41a that are elastic and are arranged so as to face each other are formed in the distal end portion of the base end side member 4a so as to protrude in the distal end direction.
  • Each has a claw 42a projecting outward.
  • claw 42a is inserted in each hole 41b from the inner side of the front end side member 4b, and when each nail
  • bonding such as adhesion
  • the outer cylinder 4 is formed at the body portion 41, the distal end portion of the body portion 41, the reduced diameter portion 42b having a diameter reduced with respect to the body portion 41, and the proximal end portion of the body portion 41, A diameter-reduced portion 45 a having a diameter reduced with respect to the body portion 41 is provided.
  • a stepped portion 421b is formed on the inner peripheral portion of the reduced diameter portion 42b.
  • a pair of long holes 43b penetrating through the body 41 is formed in the body 41 of the distal end side member 4b.
  • the long holes 43b are arranged so as to face each other via the shaft 60.
  • each long hole 43b is the same, hereafter, one long hole 43b is demonstrated typically.
  • the long hole 43 b extends along the shaft 60. Further, the end face on the base end side of the long hole 43 b is an inclined surface that is inclined at a predetermined angle with respect to the shaft 60.
  • a pair of arm portions 43a which are elastic and are arranged so as to face each other are formed in the base end portion of the body portion 41 of the base end side member 4a so as to protrude in the base end direction.
  • Claws (convex portions) 44a projecting outward are formed at the base end portions of the portions 43a.
  • claw 44a is arrange
  • ribs 431a are formed at the base end portions of the respective arm portions 43a and at positions closer to the distal end side than the claws 44a.
  • the projecting pieces 46 a and 48 a are arranged to face the base end portion (opening portion) of the reduced diameter portion 45 a of the base end side member 4 a so as to project toward the shaft 60.
  • the inner cylinder 3 is installed between the protruding pieces 46a and 48a of the base end side member 4a and the reduced diameter portion 42b of the tip end side member 4b, and thereby the axial direction of the inner cylinder 3 with respect to the outer cylinder 4 is increased. Movement is prevented. Further, the outer cylinder 4 constituted by the proximal end side member 4 a and the distal end side member 4 b is rotatable around the shaft 60 with respect to the inner cylinder 3.
  • each cam groove 42 is formed so as to penetrate the wall portion of the trunk portion 41, but is not limited thereto, and may not penetrate the wall portion of the trunk portion 41. Since each cam groove 42 is the same, one cam groove 42 will be described below representatively.
  • the cam groove 42 includes a linear groove 421 formed linearly in the direction of the axis 60 on the outer peripheral surface of the body portion 41, an inclined groove 422 formed so as to be inclined at a predetermined angle with respect to the axis 60, and the direction of the axis 60. And a straight groove 423 formed linearly.
  • the distal end portion of the linear groove 423 is located on the proximal end side with respect to the distal end portion of the linear groove 421, and the proximal end portion of the linear groove 423 is located on the proximal end side with respect to the proximal end portion of the linear groove 421.
  • the inclined groove 422 is formed shorter than one round.
  • the linear groove 421, the inclined groove 422, and the linear groove 423 are continuously formed in this order from the left side to the right side in FIG.
  • the base end portion of the linear groove 421 and the tip end portion (left end portion in FIG. 1) of the inclined groove 422 communicate with each other, and the base end portion (right end portion in FIG. 1) of the inclined groove 422
  • the base end of the linear groove 423 communicates.
  • the outer cylinder 4 is rotated relative to the cover member 6 and the inner cylinder 3 in the direction of the axis 60 by the cam groove 42 and the projection 63 of the cover member 6. That is, it rotates a predetermined angle to the left in FIG.
  • a puncture needle 7 is disposed at the distal end of the cylinder 2.
  • the puncture needle 7 includes a double-ended needle 71 and a support member 72 that supports and fixes the double-ended needle 71.
  • the double-ended needle 71 is a hollow needle tube, has a sharp distal needle tip 711 at the distal end, and a sharp proximal needle tip 712 at the proximal end.
  • This double-ended needle 71 can puncture a living body with the distal needle tip 711 and can pierce the sealing member 11 of the inner cylinder 3 with the proximal needle tip 712.
  • the lumen portion (hollow portion) of the double-ended needle 71 communicates with the inner cylinder 3 and allows the liquid from the inner cylinder 3 to pass therethrough. Functions as a road. Further, the liquid is injected into the living body through the flow path of the double-ended needle 71 in a state where the living body is punctured from the skin to a predetermined depth with the tip side needle tip 711.
  • constituent material of the double-ended needle 71 is not particularly limited, and examples thereof include metal materials such as stainless steel, aluminum or aluminum alloy, titanium or titanium alloy.
  • the double-ended needle 71 having such a configuration is attached to the distal end portion of the outer cylinder 4 (cylinder body 2) via the support member 72, that is, the reduced diameter portion 42b so as to be movable along the axis 60 direction.
  • the support member 72 supports the double-ended needle 71 movably along the axis 60 direction with respect to the outer cylinder 4.
  • the support member 72 has a bottomed cylindrical shape.
  • the double-ended needle 71 is supported and fixed to the bottom portion of the support member 72 at an intermediate position.
  • protrusions 721 are arranged in parallel at equiangular intervals along the circumferential direction of the base end portion of the support member 72 (see FIG. 14).
  • One or a plurality of long holes (not shown) extending in the direction of the axis 60 and opening in the proximal direction are formed between the adjacent protrusions 721 of the support member 72. .
  • part of the base end side of the supporting member 72 can be elastically deformed and diameter-reduced.
  • each protrusion 721 is engaged with 421b of the reduced diameter portion 45a of the base end side member 4a, thereby preventing the puncture needle 7 from being detached from the distal end portion of the cylindrical body 2.
  • the puncture needle 7 is supported by the outer cylinder 4 through the support member 72 so as to be movable along the axis 60 direction.
  • the puncture needle 7 seals the proximal end needle tip 712 of the double-ended needle 71 from the separated state shown in FIG. 2 in which the proximal needle tip 712 of the double-ended needle 71 is separated from the sealing member 11 of the cylindrical body 2.
  • the piercing state shown in FIGS. 7 and 9 through which the stop member 11 is pierced can be taken. Therefore, unintentional leakage of the liquid from the double-ended needle 71 is prevented until the piercing state is reached.
  • the cover member 6 is disposed on the outer peripheral side of the outer cylinder 4 (tubular body 2).
  • the cover member 6 is supported so as to be relatively movable along the direction of the axis 60 with respect to the outer cylinder 4 (tubular body 2) similarly to the puncture needle 7.
  • the cover member 6 has the outer cylinder 4 (cylinder 2) so that the distal end surface 622 of the double-ended needle 71 contacts the living body before the distal end needle tip 711 is punctured from the skin to a predetermined depth of the living body.
  • a first position see FIGS. 1 and 2 that protrudes more distally
  • a second position see FIGS. 6 to 9 that retracts from the first position in the proximal direction. it can.
  • the distal end surface 622 of the cover member 6 protrudes from the distal end side needle tip 711 of the double-ended needle 71 to the distal end side, and the double-ended needle is detected by the cover member 6.
  • the tip end needle tip 711 of 71 is covered.
  • the distal end needle tip 711 of the double-ended needle 71 is not exposed until the cover member 6 moves from the first position to the proximal end side, the distal end needle tip 711 of the double-ended needle 71 before the user punctures. Can be prevented from being erroneously pierced and the tip side needle tip 711 being damaged.
  • the distal end side needle tip 711 of the double-ended needle 71 is exposed from the distal end surface 622 of the cover member 6.
  • the puncture needle 7 described above is in a separated state located on the proximal side from the distal end portion of the cover member 6, and the cover member 6 has come to the second position. At this time, the cover member 6 presses and moves the puncture needle 7 (the double-ended needle 71 together with the support member 72) toward the proximal end, and enters the piercing state.
  • the cover member 6 includes a plate-like distal end wall portion 62 disposed at the distal end portion and a side wall 61 erected in the proximal direction from the distal end wall portion 62, that is, has a bottomed cylindrical shape. It is composed of members.
  • the cover member 6 has a tip surface 622 at the tip.
  • an opening 621 that passes through the center is formed.
  • the tip side needle tip 711 of the double-ended needle 71 protrudes (exposes) from the opening 621.
  • the side wall 61 has a cylindrical shape.
  • a pair of protrusions 611 are formed on the outer peripheral surface of the base end portion of the side wall 61 so as to protrude outward and to face each other.
  • a pair of arm portions 612 having elasticity and arranged so as to face each other are formed to protrude in the proximal direction, and at the proximal end portion of each arm portion 612, Protrusions 613 projecting inward are formed.
  • Each protrusion 613 is disposed on the distal end side of the base end of the side wall 61.
  • the arm portions 612, the protrusions 613, and the protrusions 611 are alternately arranged at equiangular intervals along the circumferential direction of the cover member 6.
  • a pair of protrusions 63 are formed on the inner peripheral surface of the base end portion of the side wall 61 so as to protrude inward and to be opposed to each other (see FIG. 1).
  • Each protrusion 63 is inserted into each cam groove 42 of the outer cylinder 4, that is, engages with each cam groove 42.
  • each protrusion 613 of the cover member 6 is inserted into each long hole 43b of the outer cylinder 4 respectively.
  • each projection 613 of the cover member 6 is respectively a base end of the first display portion 45 b configured by a pair of long holes described later. Move to the side.
  • a coil spring 13 is housed inside the cover member 6.
  • the distal end of the coil spring 13 is in contact with the distal end wall 62 of the cover member 6, and the proximal end is in contact with the distal end of the body 41 of the outer cylinder 4.
  • the coil spring 13 is slightly compressed due to the weight applied to the tip of the outer cylinder 4.
  • the cover member 6 can be urged in the direction from the second position toward the first position (ie, urged toward the front end direction).
  • Such a biasing force of the coil spring 13 allows the distal end surface 622 of the cover member 6 to protrude from the distal end side needle tip 711 of the double-ended needle 71 to the distal end side until the liquid administration device 10 is used. An erroneous puncture by the tip side needle tip 711 can be reliably prevented.
  • the constituent material of the coil spring 13 is not particularly limited, and for example, a metal material such as stainless steel can be used.
  • the gasket 8 is accommodated in the inner cylinder 3 so as to be slidable along the shaft 60.
  • the space surrounded by the gasket 8 and the inner cylinder 3 is preliminarily filled with liquid. Then, by moving the gasket 8 toward the distal direction, the liquid in the inner cylinder 3 can be pushed out from the double-ended needle 71 in a state communicating with the inner cylinder 3.
  • the gasket 8 has a cylindrical outer shape, and four protrusions 81 are formed on the outer periphery thereof. Adjacent protrusions 81 and protrusions 81 are spaced apart along the axis 60 direction. Each protrusion 81 has a ring shape along the circumferential direction of the gasket 8, and its outer diameter is slightly larger than the inner diameter of the inner cylinder 3 in a natural state where no external force is applied. Accordingly, each protrusion 81 can slide while being in close contact with the inner peripheral portion of the side wall 33 of the inner cylinder 3, so that liquid-tightness is reliably maintained and slidability is improved. Can be planned.
  • a recess 82 is formed in the base end surface of the gasket 8 to be connected by inserting (fitting) the connecting portion 513 of the pusher 51 of the operation member 5.
  • the pusher 51 and the gasket 8 may not be connected (not shown).
  • the operation member 5 includes a pusher 51 that is connected to the proximal end side of the gasket 8 and presses the gasket 8 toward the distal end direction, and a grip portion 52.
  • the pusher 51 and the grip portion 52 are connected.
  • the operation member 5 moves the pusher 51 in the distal direction, thereby moving the gasket 8 toward the distal direction, thereby discharging the liquid in the inner cylinder 3 from the double-ended needle 71 (hereinafter, this operation). Is a member that is gripped when performing a “pressing operation”.
  • the pusher 51 has a rod-like main body portion 511 whose cross section has a cross shape or a circular shape, for example, and the gasket 8 is fixed to the tip of the main body portion 511.
  • a disc-shaped top plate 512 is formed at the base end of the main body 511.
  • a connecting portion 513 corresponding to the shape of the concave portion 82 of the gasket 8 is formed at the tip of the main body portion 511.
  • the pusher 51 (operation member 5) and the gasket 8 are connected.
  • the method of fixing the gasket 8 to the main body 511 is not limited to this.
  • a male screw is formed on the main body 511 and a female screw is formed on the gasket 8 to be screwed to the male screw. And a method of screwing the two together.
  • a pair of arm portions 514 that are elastic and are disposed so as to face each other are formed on the base end surface of the top plate 512 of the pusher 51 so as to protrude in the distal direction.
  • Each part has a claw 515 protruding outward.
  • step portions 516 are formed at the tip of the main body 511 of the pusher 51.
  • the step portions 516 are arranged at equiangular intervals along the circumferential direction of the main body portion 511.
  • each step portion 516 of the pusher 51 is engaged with the projecting pieces 46 a and 48 a of the outer cylinder 4, whereby the pusher 51 is moved toward the distal end direction of the pusher 51 with respect to the cylindrical body 2. Movement is blocked.
  • each step of the pusher 51 The portion 516 moves to a position shifted from the protruding pieces 46a and 48a of the outer cylinder 4, and the engagement between each stepped portion 516 and the protruding pieces 46a and 48a is released, whereby the tip of the pusher 51 with respect to the cylindrical body 2 is released. Allows movement in the direction.
  • the grip portion 52 is disposed on the outer peripheral side of the inner structure 1 and the cover member 6.
  • the grip portion 52 has a cylindrical shape, and has a shape that is easy to grip when operating the operation member 5.
  • a pair of hole portions 521 arranged so as to face each other are formed at the proximal end portion of the grip portion 52. And each nail
  • the method of connecting the base end side member 4a and the front end side member 4b is not limited to this,
  • bonding such as adhesion
  • the notification mechanism 9 includes a vibration generating unit 91 for notifying the completion of discharge by generating a sound (audible sound) or vibration when the discharge of the liquid is completed by a pressing operation, and the discharge completion (administration completion). ) With a visual recognition part 92 having a function of notifying by visual recognition.
  • the vibration generating portion 91 is provided on the protruding pieces (first engaging portions) 47 a and 49 a provided on the proximal end side member 4 a of the inner structure 1 and the pusher 51 of the operation member 5. And an enlarged diameter portion (second engagement portion) 517 provided.
  • the protruding pieces (first engaging portions) 47a and 49a are disposed to face the proximal end portion (opening portion) of the reduced diameter portion 45a of the proximal end side member 4a.
  • the protruding pieces 47 a and 49 a have elasticity and are formed to protrude toward the shaft 60. Further, the protruding pieces 47a and 49a protrude toward the shaft 60 rather than the protruding pieces 46a and 48a described above.
  • the protruding pieces 47a and 49a and the protruding pieces 46a and 48a are arranged at equiangular intervals in the order of the protruding pieces 46a, 47a, 48a, and 49a along the circumferential direction of the reduced diameter portion 45a (opening). Yes.
  • the enlarged diameter portion (second engagement portion) 517 is formed in the middle of the main body portion 511 in the longitudinal direction, and the outer diameter of the enlarged portion is increased.
  • the enlarged diameter portion 517 overlaps the end portions on the shaft 60 side of the protruding pieces 47a and 49a.
  • the enlarged diameter portion 517 has an inclined surface 510 whose outer diameter gradually increases from the distal end side toward the proximal end side at the distal end side.
  • the gasket 8 slides in the inner cylinder 3 toward the tip side by a pressing operation.
  • the pressing operation is continued and the remaining amount of liquid becomes small, the gasket 8 approaches the bottom portion 32 of the inner cylinder 3, and the enlarged diameter portion 517 provided on the pusher 51 is a protruding piece provided on the base end side member 4a. Abuts with 47a and 49a.
  • the pressing operation is further continued, the discharge of the liquid is completed, and the protruding pieces 47a and 49a are elastically deformed, that is, curved in a direction perpendicular to the shaft 60, and the enlarged-diameter portion 517 becomes the protruding pieces 47a and 49a. At that moment, sound (audible sound) and vibration (click feeling) are generated from the protruding pieces 47a and 49a.
  • the user can detect the generated sound and thereby recognize the completion of the liquid ejection.
  • the generated vibration is transmitted to the grip portion 52, and the user senses the vibration and sound. Accordingly, the user can more reliably recognize the completion of the liquid ejection.
  • the visual recognition unit 92 includes a first display unit 45b, a second display unit 46b, a third display unit 47b, a fourth display unit 48b, A cover member side window 614 and an operation member side window 520 are provided.
  • the visual recognition unit 92 has a function of notifying the completion by visual recognition when the discharge of the liquid is completed.
  • the first display portion 45b is disposed on the body portion 41 of the distal end side member 4b so as to face each other through the shaft 60.
  • Each first display part (outer cylinder side window part) 45b is configured by a long hole that penetrates the body part 41 of the distal end side member 4b and can visually recognize the liquid filled in the inner cylinder 3.
  • the first display unit 45b (the first display unit 45b on the front side in FIG. 4) displays the initial state.
  • Each first display portion 45b is provided at a position shifted in the longitudinal direction with respect to the long hole 43b, that is, on the right side of the long hole 43b in FIG. Further, the end face on the base end side of each first display portion 45b is located on the base end side with respect to the end face on the base end side of the long hole 43b.
  • the second display unit 46b is composed of a triangular yellow marker having a base 460b on the tip side, and displays the progressing state (second state) of the liquid discharge by changing the shape of the displayed part. is there.
  • the shape of the second display portion 46b is an isosceles triangle having a base 460b on the distal end side and an apex angle 461b on the proximal end side.
  • the second display portion 46b has an apex angle 461b that is smaller than 90 ° and is long in the direction of the axis 60. In other words, the second display portion 46b extends along the axis 60 and gradually increases in width toward the distal direction.
  • the second display portion 46b is arranged at a position shifted in the circumferential direction of the body portion 41 with respect to the first display portion 45b, that is, at the right side in FIG. Further, the base 460b of the second display portion 46b is located on the distal end side with respect to the end surface on the proximal end side of the first display portion 45b. Further, the apex angle 461 b on the base end side of the second display portion 46 b is located at the base end of the body portion 41.
  • the third display unit 47b is configured by a rectangular red marker extending along the axis 60, and the third display unit 47b is configured such that the cover member 6 is located at the second position and the inner cylinder 3 and the two heads A state (third state) in which the needle 71 is in communication is displayed.
  • the third display portion 47b is arranged at a position shifted in the longitudinal direction of the body portion 41 with respect to the first display portion 45b, that is, on the upper side in FIG. Further, the third display unit 47b is arranged at a position shifted in the circumferential direction with respect to the second display unit 46b, that is, shifted to the left side in FIG.
  • the fourth display portion 48b is composed of a rectangular blue marker extending along the axis 60, and the cover member 6 is returned from the second position to the first position again after the liquid discharge is completed. (Fourth state) is displayed. Further, the fourth display portion 48b is arranged at a position shifted in the circumferential direction of the body portion 41 with respect to the first display portion 45b, that is, on the right side in FIG. Further, the fourth display portion 48b is arranged at a position shifted in the longitudinal direction of the body portion 41 with respect to the second display portion 46b, that is, on the lower side in FIG.
  • the first display unit 45b, the second display unit 46b, the third display unit 47b, and the fourth display unit 48b are provided at different positions on the body 41.
  • the long hole 43b and the third display portion 47b are in the same position in the circumferential direction of the body portion 41
  • the second display portion 46b and the fourth display portion 48b are in the circumferential direction of the body portion 41.
  • the position is the same.
  • the 2nd display part 46b, the 3rd display part 47b, and the 4th display part 48b are comprised by the marker from which at least 1 conditions of a color and a shape differ.
  • the cover member side window 614 is provided in the middle (base end portion) of the side wall 61 of the cover member 6, and is configured by a long hole that penetrates the side wall 61 and can visually recognize the inside. Yes.
  • the cover member-side window 614 is arranged at a position shifted in the circumferential direction of the side wall 61 with respect to one arm 612 of the cover member 6, that is, shifted to the right in FIG.
  • the operation member side window 520 is provided in the middle (tip portion) of the grip portion 52 of the operation member 5, and is a long hole that penetrates the grip portion 52 and can visually recognize the inside. It is configured.
  • the position of the operation member side window 520 in the circumferential direction is the same as that of the cover member side window 614. That is, when the cover member 6 is located at the second position, the operation member side window 520 and the cover member side window 614 overlap in a side view.
  • the viewing unit 92 having such a configuration obtains the following first display unit viewing state, second display unit viewing state, third display unit viewing state, and fourth display unit viewing state. Can do.
  • the 16 is a state in which the first display portion 45b can be visually recognized through the cover member side window 614 of the cover member 6.
  • the first display portion visible state shown in FIG. Thereby, the user can recognize that the liquid administration device 10 is in an initial state.
  • the second display portion 46 b is visually recognized via the operation member side window 520 of the operation member 5 and the cover member side window 614 of the cover member 6. It is a state that can be done. Accordingly, the user can grasp the progress of the liquid discharge, and can recognize, for example, the start of liquid discharge, the completion of discharge, and the like.
  • the third display portion 47 b is visually recognized via the operation member side window 520 of the operation member 5 and the cover member side window 614 of the cover member 6. It is ready. As a result, the user can recognize that the tip side needle tip 711 of the double-ended needle 71 protrudes from the opening 621.
  • the fourth display portion 48 b is visually recognized through the operation member side window 520 of the operation member 5 and the cover member side window 614 of the cover member 6. It is ready. Thereby, the user can recognize that the tip side needle tip 711 of the double-ended needle 71 is covered with the cover member 6.
  • the user can perform administration while grasping the state of the liquid administration device 10 by the visual recognition unit 92.
  • the shapes and colors of the second display section 46b, the third display section 47b, and the fourth display section 48b are not limited to those described above.
  • the auxiliary mechanism 40 has a function of generating an auxiliary force that presses the gasket 8 via the pusher 51 of the operation member 5.
  • the auxiliary mechanism 40 includes a pair of coil springs (second urging members) 401.
  • the coil spring 401 is in an extended state, and has a proximal end portion fixed to the top plate 512 of the pusher 51 and a distal end portion fixed to the outer cylinder 4.
  • the coil spring 401 biases the inner structure 1 and the operation member 5 in a direction approaching each other. That is, the coil spring 401 generates an auxiliary force that presses the gasket 8 in the distal direction via the pusher 51 of the operation member 5.
  • the operation member 5 can be easily moved in the distal direction.
  • the auxiliary force transmission prevention mechanism 50 has a function of preventing the auxiliary force of the coil spring 401 (auxiliary mechanism 40) from being transmitted to the gasket 8 during the pressing operation.
  • the auxiliary force transmission preventing mechanism 50 has a function of preventing the auxiliary force of the auxiliary mechanism 40 from being transmitted to the gasket 8 even in the initial state.
  • the auxiliary force transmission preventing mechanism 50 has a function of changing from a state in which the auxiliary force of the auxiliary mechanism 40 is prevented from being transmitted to the gasket 8 to a state in which the auxiliary force is transmitted to the gasket 8.
  • the auxiliary force transmission preventing mechanism 50 includes a pair of claws 44 a of the outer cylinder 4 and a plurality of holes 522 described later of the grip 52. It is comprised by the base end part of the side wall 61 of the cover member 6. FIG.
  • a plurality of sets of a pair of hole portions (recess portions) 522 that are engaged with the pair of claws 44 a of the outer cylinder 4 and are opposed to each other are formed on the wall portion of the grip portion 52.
  • Each hole 522 is arranged in parallel along the axis 60 direction at equal intervals.
  • the pair of claws 44a of the outer cylinder 4 are inserted into any one of the pair of hole portions 522 from the inside of the grip portion 52, and the respective inner claws 44a and the respective hole portions 522 are engaged with each other.
  • the positional relationship with the operation member 5 is fixed, that is, the movement in the direction of the axis 60 with respect to the inner structure 1 is prevented.
  • each arm portion 43a bends inward.
  • the engagement between each claw 44a and each hole 522 is released, and movement in the direction of the axis 60 with respect to the inner structure 1 becomes possible (see FIGS. 9 and 11). Therefore, the side wall 61 of the cover member 6 constitutes a release portion that releases the engagement between each claw 44a and each hole 522.
  • each groove extends along the direction of the axis 60. And each protrusion 611 of the cover member 6 is inserted in each groove
  • FIG. 1 a method of using the liquid administration device 10 and an operating state at the time of use will be described with reference to FIGS. 1, 2, and 6 to 20.
  • FIG. 1 a method of using the liquid administration device 10 and an operating state at the time of use will be described with reference to FIGS. 1, 2, and 6 to 20.
  • an initial liquid administration device 10 is prepared.
  • the cover member 6 is in the first position and covers the tip side needle tip 711 of the double-ended needle 71.
  • the initial state the state in which the tip side needle tip 711 of the double-ended needle 71 is covered with the cover member 6 by the biasing force of the coil spring 13 is maintained. Thereby, the erroneous puncture by the front end side needle tip 711 of the double-ended needle 71 can be reliably prevented.
  • the proximal end needle tip 712 of the double-ended needle 71 is separated from the sealing member 11 of the inner cylinder 3 of the cylindrical body 2, and the sealing member 11 has not yet been pierced. Thereby, the aseptic state of the liquid can be maintained until the administration of the liquid is started.
  • the pair of claws 44a of the outer cylinder 4 are inserted into the pair of hole portions 522 on the most distal end side of the grip portion 52, and each of the claws 44a and each hole portion 522 engage with each other, whereby the inner structure 1 The movement of the operation member 5 with respect to the (tubular body 2) in the distal direction is prevented.
  • each step portion 516 of the pusher 51 is engaged with the protruding pieces 46 a and 48 a of the outer cylinder 4, thereby preventing the operation member 5 from moving in the distal direction with respect to the inner structure 1.
  • the cover member side window 614 of the cover member 6 and the first display portion 45b of the outer cylinder 4 are overlapped in side view, that is, the first display portion is visually recognized. It has become.
  • the first display portion visual recognition state the user can visually recognize the liquid filled in the inner cylinder main body 31. Accordingly, the user can easily distinguish the liquid administration device 10 in the initial state from the used liquid administration device 10.
  • the grasping portion 52 of the operation member 5 of the liquid administration device 10 in the initial state is grasped, and the distal end wall portion 62 of the cover member 6 is brought into contact with the living body. Then, the operation member 5 is pressed toward the distal direction. Accordingly, the cover member 6 starts to move in the proximal direction, that is, from the first position to the second position with respect to the operation member 5 and the inner structure 1 against the urging force of the coil spring 13. In this process, the distal needle tip 711 of the double-ended needle 71 protrudes from the opening 621 of the distal wall 62 of the cover member 6 and is first punctured with the distal needle tip 711.
  • the distal end wall portion 62 of the cover member 6 comes into contact with the distal end portion of the support member 72 of the puncture needle 7 and the distal end wall portion 62 presses the support member 72 of the puncture needle 7 toward the proximal direction.
  • the sealing member 11 of the inner cylinder 3 can be pierced by the proximal end needle tip 712 of the double-ended needle 71, and thus the double-ended needle 71 that has punctured a living body and the inner cylinder 3 communicate with each other ( Second position).
  • the operation member side window 520 of the operation member 5 and the cover member side window 614 of the cover member 6 partially overlap in a side view, that is, the third display portion is visually recognized. It is in a state.
  • the third display portion visual recognition state the user can visually recognize the third display portion 47b.
  • the user can easily recognize that the tip side needle tip 711 of the double-ended needle 71 is in a state of protruding from the opening 621.
  • the third display unit 47b is configured with a red marker, the user is in a state where the tip side needle tip 711 of the double-ended needle 71 protrudes from the opening 621 and erroneous puncture can occur. Can be easily recognized.
  • the state in which the operation member side window 520 of the operation member 5 and the cover member side window 614 of the cover member 6 partially overlap is maintained until the cover member 6 returns to the first position again (FIG. 17). To FIG. 20).
  • step-difference part 516 of the pusher 51 moves to the position shifted
  • the base end portion of the side wall 61 of the cover member 6 moves to the position of the rib 431 a of each arm portion 43 a of the outer cylinder 4, and at this position, each arm portion 43 a is directed inward. Press.
  • each arm part 43a bends inward, and each nail
  • the protrusions 613 of the cover member 6 are moved relatively on the outer cylinder 4 in accordance with the rotation of the predetermined angle, and are moved to the base end side of the long holes 43b.
  • the second display is performed via the operation member side window 520 and the cover member side window 614.
  • the part 46b can be visually recognized, that is, the second display part is visually recognized.
  • the user places the operation member side window portion 520 around the apex angle 461 b of the second display portion 46 b that forms a triangle formed of yellow markers. And the cover member side window 614. Thereby, the user can easily recognize that the liquid administration device 10 is in a state where the liquid can be administered to the living body. Note that the second display portion visual recognition state is maintained until the administration of the liquid is completed.
  • the enlarged diameter portion 517 provided on the pusher 51 gets over the protruding pieces 47a and 49a provided on the base end side member 4a, and the protruding pieces 47a and 49a Vibrate. Thereby, the user can recognize completion of discharge.
  • the operation member side window portion 520 maintains the state where it overlaps the cover member side window portion 614 of the cover member 6, and the front end side. Move to.
  • the part of the second display unit 46b displayed in the second display unit viewing state is changed from the vicinity of the apex angle 461b to the vicinity of the base 460b.
  • the second display unit 46b moves in the proximal direction relative to the operation member side window 520, and retracts from the apex angle 461b to the proximal side of the operation member side window 520.
  • the bottom 460b side enters the operation member side window 520.
  • the user visually recognizes the vicinity (tip portion) of the bottom 460b of the second display unit 46b.
  • the user can easily recognize the progress of the administration and can predict or confirm the completion of the discharge.
  • the user can recognize the completion of the discharge more reliably because the user can detect the audible sound and the vibration by the vibration generating unit 91 while grasping the progress of the administration by the visual recognition unit 92.
  • the cover member 6 is moved in the distal direction, that is, the first position by the urging force of the coil spring 13, and the distal end needle tip 711 of the double-ended needle 71 is covered with the cover member 6.
  • each projection 613 of the cover member 6 engages with the proximal end portion of the long hole 43b, so that the cover member 6 is prevented from moving in the proximal direction, and the distal needle tip 711 of the double-ended needle 71 is moved by the cover member 6. The covered state is maintained.
  • the user can visually recognize the fourth display portion 48b through the operation member side window portion 520 and the cover member side window portion 614. That is, the fourth display unit is visually recognized.
  • the fourth display portion visual recognition state the user can easily confirm that the distal end side needle tip 711 of the double-ended needle 71 is covered with the cover member 6.
  • the fourth display portion 48b is configured with a blue marker, the user can easily confirm that the distal end needle tip 711 of the double-ended needle 71 is in a safe state covered with the cover member 6. Can be recognized.
  • the liquid administration device 10 in the blocking state, is in the second display portion viewing state. Thereby, the user can recognize the progress state of the discharge of the liquid. That is, the user can recognize that the liquid that can be administered remains in the inner cylinder 3.
  • the vibration generating unit 91 In the completed state where the administration of the liquid is completed, as described above, the vibration generating unit 91 notifies the completed state. At this time, the operation of the auxiliary mechanism 40 is also completed. Completion of the operation of the auxiliary mechanism 40 is also confirmed by sound or vibration generated by the vibration generator 91. Thus, the vibration generating unit 91 also serves as a notification of the completion of the operation of the auxiliary mechanism 40. Thereby, it is possible to omit providing a separate mechanism for notifying the completion of the operation of the auxiliary mechanism 40 in the liquid administration device 10. Thus, the liquid administration device 10 has a simple structure.
  • the discharge (administration) of the liquid is completed, and the sound and vibration are generated when the protruding pieces 47a and 49a get over the enlarged diameter portion 517, thereby discharging the liquid. Since the completion is notified, the user can recognize that the liquid ejection has been completed. Accordingly, it is possible to reliably prevent the user from removing the puncture needle 7 from the living body in a state where the administration of the liquid is not completed, and thus the amount of the liquid administered to the user is insufficient. Can be reliably prevented. Therefore, a sufficient amount of liquid can be reliably administered to the living body.
  • the visual confirmation unit 92 having a function of visually informing the completion of the discharge of the liquid is provided, the user can visually confirm the administration before the discharge of the liquid, during the discharge, the completion of the discharge, etc.
  • the progress state can be recognized. This can more reliably prevent the user from removing the needle tube from the living body in a state where the administration of the liquid is not completed, and therefore the amount of liquid administered to the user is insufficient. It can prevent more reliably. Therefore, a sufficient amount of liquid can be reliably administered by the living body.
  • the user can perform only the pressing operation from the initial state to the completion of administration (completed state). That is, the user can administer the liquid by one action (one operation). Further, the user can recognize the completion of liquid administration, the progress of liquid administration, and the like by the notification mechanism 9. Thereby, the user can operate the liquid administration tool 10 simply.
  • the urging force of the coil spring 401 can assist the movement of the operation member 5 in the distal direction.
  • a user who is relatively weak in pressing the operation member 5 such as an elderly person or a woman
  • a user who has difficulty with fingers such as a rheumatic patient, and the like that is difficult to press the operation member 5
  • the liquid administration is temporarily interrupted, for example, when the pain due to the liquid is relatively strong, even if the biasing force of the coil spring 401 is acting, the hole 522 and the claw 44a are engaged.
  • the movement of the operation member 5 in the distal direction is restricted and can be interrupted. Thereby, it is possible to prevent the liquid from being wasted or insufficient, and a sufficient amount of the liquid can be administered to the living body.
  • FIG. 22 is a perspective view of a vibration generating unit of the second embodiment of the liquid administration device of the present invention.
  • the upper side in FIG. 22 is “base end (rear end)” or “upper (upper)”
  • the lower side is “tip” or “lower (lower)”
  • the vertical direction is “axial direction” or “ The description is given as “longitudinal direction”.
  • This embodiment is the same as the first embodiment except that the shape of the vibration generating portion is different.
  • the vibration generating portion 91 ′ of the present embodiment includes a pair of arms 40 a provided on the base end side member 4 a and a pair of claw portions 518 provided on the operation member 5.
  • a pair of arms 40a extending in the base end direction are disposed opposite to the base end surface of the reduced diameter portion 45a of the base end side member 4a.
  • the pair of claw portions 518 are formed on the front end surface of the top plate 512 of the operation member 5 so as to protrude in the front end direction. Since the configuration of each arm 40a is the same, one arm 40a will be described below as a representative. Similarly, since the configuration of each claw portion 518 is the same, one claw portion 518 will be typically described below.
  • the arm 40a has elasticity, and has a recess (first engagement portion) 400a inside the base end portion. Further, an inclined portion 401a in which the width direction of the arm 40a, that is, the length in the radial direction of the base end side member 4a gradually decreases toward the base end is formed in the base end side portion of the recess 400a of the arm 40a. ing.
  • a protrusion (second engagement portion) 519 that protrudes outward and engages with the recess 400a is formed at the tip of the claw portion 518.
  • the convex portion 519 of the claw portion 518 comes into contact with the inclined portion 401a and slides toward the tip side along the inclined direction. At this time, the elastic arm 40a is pushed outward and curved.
  • the convex portion 519 gets over the inclined portion 401a and reaches (engages) the concave portion 400a of the arm 40a. At that moment, sound (audible sound) and vibration (click feeling) are generated from one arm 40a.
  • the first engagement portion and the second engagement portion are provided along the direction in which the operation member 5 moves. Thereby, the arm 40a and the claw portion 518 are not easily damaged.
  • FIG. 23 is a longitudinal sectional view sequentially illustrating the operating state of the third embodiment of the liquid administration device of the present invention
  • FIG. 24 illustrates the operating state of the liquid administration device of the present invention when the third embodiment is used. It is a longitudinal section shown in order.
  • the upper side in FIGS. 23 and 24 is “base end (rear end)” or “upper (upper)”
  • the lower side is “tip” or “lower (lower)”
  • the vertical direction is “axial direction”.
  • “Or” longitudinal direction is “.
  • This embodiment is the same as the first embodiment except that the shape of the vibration generating portion is different.
  • the vibration generating portion 91A of the present embodiment includes a pair of arms 40b provided on the base end side member 4a and a pair of claws 518a provided on the operation member 5. Has been.
  • a pair of arms 40b extending in the proximal direction are disposed opposite to the proximal surface of the reduced diameter portion 45a of the proximal member 4a.
  • the pair of claw portions 518 a are formed on the front end surface of the top plate 512 of the operation member 5 so as to protrude in the front end direction. Since the configuration of each arm 40b is the same, one arm 40b will be typically described below. Similarly, since the configuration of each claw portion 518a is the same, one claw portion 518a will be described below as a representative.
  • the arm 40b has elasticity, and has a convex portion (first engaging portion) 400b inside the base end portion.
  • an inclined portion 401b in which the width direction of the arm 40b, that is, the radial length of the base end side member 4a gradually decreases in the base end direction is formed in the base end side portion of the convex portion 400b of the arm 40b.
  • a protrusion (second engagement portion) 519a that protrudes inward and engages with the protrusion 400b is formed at the tip of the claw portion 518a.
  • the convex portion 519a of the claw portion 518a comes into contact with the inclined portion 401b and slides toward the tip side along the inclined direction. At this time, the elastic arm 40a is pressed inward and curved.
  • the convex portion 519a gets over (engages) the inclined portion 401b. At that moment, sound (audible sound) and vibration (click feeling) are generated from the pair of arms 40b and the pair of claws 518a.
  • the outer cylinder 4 and the operation member 5 are fixed by the engagement of the pair of arms 40b and the pair of claws 518a. Thereby, while being able to control the action
  • liquid administration device of the present invention has been described based on the illustrated embodiment, but the present invention is not limited to this, and the configuration of each part is replaced with an arbitrary configuration having the same function. can do. In addition, any other component may be added to the present invention.
  • the puncture needle has a needle tube that is a double-ended needle, but in the present invention, the puncture needle is not limited to this, and has a needle tube in which the proximal end needle tip is omitted. Also good. In this case, the needle tube communicates with the inner cylinder in advance (already in the initial state).
  • the present invention may be a combination of any two or more configurations (features) of the above embodiments.
  • the cylinder is preliminarily filled with the liquid.
  • the present invention is not limited to this.
  • the cylinder is not initially filled with the liquid, and the cylinder is filled with liquid later. It may be filled and used.
  • the notification mechanism notifies the completion state of the liquid administration, but the present invention is not limited to this, and may notify the completion of the liquid administration.
  • the 1st display part, the operation member side window part, and the cover member side window part are each comprised by the through-hole, in this invention, it is not limited to this,
  • the window portion may be made of a transparent material.
  • the protrusion piece has elasticity among the enlarged diameter part of an operation member, and the protrusion piece of an inner side structure, it is not limited to this in this invention,
  • diameter expansion The part may have elasticity, or both may have elasticity.
  • the first urging member is a compression spring.
  • the first urging member is not limited to this.
  • a tension spring or the like may be used.
  • the second urging member is a tension spring.
  • the second urging member is not limited to this, and may be, for example, a compression spring or the like, or may be other than a spring.
  • the cylinder body with which a gasket slides inside was comprised with two members, an inner cylinder and an outer cylinder, in this invention, it is not limited to this, For example, it comprises with one member. May be.
  • the present invention is not limited to this.
  • the concave portion of the blocking mechanism may be provided in the inner structure, and the convex portion may be provided in the operation member.
  • the liquid administration device of the present invention has a bottom at the distal end and an opening at the proximal end, an inner cylinder that can be filled with liquid, and a sharp needle tip attached to the distal end of the inner cylinder.
  • An inner structure including a needle tube whose base end can communicate with the inside of the inner cylinder, and a gasket that is installed in the inner cylinder and that can slide along the axial direction of the inner cylinder, and the gasket.
  • An operation member for performing a pressing operation for moving the pressing element in a distal direction and discharging the liquid filled in the inner cylinder from the needle tube; and the liquid by the pressing operation.
  • a notifying mechanism having a vibration generating part for notifying the completion by generating sound or vibration when the discharge is completed.
  • the completion state is notified to the user by generating sound or vibration.
  • the user can recognize that the discharge of the liquid has been completed, and can reliably prevent the needle tube from being removed from the living body in a state where the administration has not been completed. Therefore, it can prevent reliably that the quantity of the liquid formulation administered to a user becomes inadequate. Therefore, a sufficient amount of liquid can be reliably administered to the living body.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'instrument pour administration de liquide (10) de l'invention est équipé d'une structure interne (1) qui est à son tour équipée : d'un tube interne (3) qui possède une partie fond (32) au niveau d'une partie extrémité avant et une partie ouverture au niveau d'une partie extrémité de base, et qui permet de remplir d'un liquide une partie interne ; d'un tube d'aiguille (71) qui est monté sur une partie extrémité avant du tube interne (3), qui possède une pointe d'aiguille tranchante dans l'extrémité avant, et dont l'extrémité de base peut communiquer avec la partie interne du tube interne (3) ; et d'un joint statique (8) disposé à l'intérieur du tube interne (3), et pouvant coulisser suivant la direction axiale du tube interne (3). En outre, l'instrument pour administration de liquide (10) est équipé : d'un élément de manipulation qui possède un piston (51) exerçant une pression sur le joint statique (8), qui déplace ce piston (51) dans la direction extrémité avant, et qui effectue une manipulation de pression telle que le liquide remplissant le tube interne (3) est déchargé par le tube d'aiguille (71) ; et d'un mécanisme de notification (9) qui possède une partie génératrice d'oscillation (91) qui lorsque la décharge du liquide par manipulation de pression est achevée, notifie son achèvement par génération d'un bruit ou d'une oscillation.
PCT/JP2013/050190 2013-01-09 2013-01-09 Instrument pour administration de liquide WO2014109012A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/JP2013/050190 WO2014109012A1 (fr) 2013-01-09 2013-01-09 Instrument pour administration de liquide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2013/050190 WO2014109012A1 (fr) 2013-01-09 2013-01-09 Instrument pour administration de liquide

Publications (1)

Publication Number Publication Date
WO2014109012A1 true WO2014109012A1 (fr) 2014-07-17

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PCT/JP2013/050190 WO2014109012A1 (fr) 2013-01-09 2013-01-09 Instrument pour administration de liquide

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019186095A1 (fr) * 2018-03-29 2019-10-03 Humboldt Uk Ltd Dispositif d'injection
EP4173655A1 (fr) * 2021-10-27 2023-05-03 medmix Switzerland AG Auto-injecteur
WO2023073058A1 (fr) * 2021-10-27 2023-05-04 Medmix Switzerland Ag Auto-injecteur

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02302266A (ja) * 1989-04-28 1990-12-14 Flp Enterp Inc 再使用不可能な注射器
JP2012500696A (ja) * 2008-08-28 2012-01-12 オウエン マンフォード リミティド 自動注射デバイス

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02302266A (ja) * 1989-04-28 1990-12-14 Flp Enterp Inc 再使用不可能な注射器
JP2012500696A (ja) * 2008-08-28 2012-01-12 オウエン マンフォード リミティド 自動注射デバイス

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019186095A1 (fr) * 2018-03-29 2019-10-03 Humboldt Uk Ltd Dispositif d'injection
EP4173655A1 (fr) * 2021-10-27 2023-05-03 medmix Switzerland AG Auto-injecteur
WO2023073058A1 (fr) * 2021-10-27 2023-05-04 Medmix Switzerland Ag Auto-injecteur

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