WO2014081071A1 - Appareil, système et procédé permettant d'obtenir des signaux biologiques provenant d'animaux de laboratoire - Google Patents

Appareil, système et procédé permettant d'obtenir des signaux biologiques provenant d'animaux de laboratoire Download PDF

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Publication number
WO2014081071A1
WO2014081071A1 PCT/KR2012/011644 KR2012011644W WO2014081071A1 WO 2014081071 A1 WO2014081071 A1 WO 2014081071A1 KR 2012011644 W KR2012011644 W KR 2012011644W WO 2014081071 A1 WO2014081071 A1 WO 2014081071A1
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WIPO (PCT)
Prior art keywords
biological signal
laboratory animal
sensor
wireless power
wireless
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PCT/KR2012/011644
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English (en)
Korean (ko)
Inventor
원윤재
김영한
임승옥
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전자부품연구원
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Publication of WO2014081071A1 publication Critical patent/WO2014081071A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/002—Monitoring the patient using a local or closed circuit, e.g. in a room or building
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J50/00—Circuit arrangements or systems for wireless supply or distribution of electric power
    • H02J50/10—Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling
    • H02J50/12—Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J50/00—Circuit arrangements or systems for wireless supply or distribution of electric power
    • H02J50/50—Circuit arrangements or systems for wireless supply or distribution of electric power using additional energy repeaters between transmitting devices and receiving devices
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J50/00—Circuit arrangements or systems for wireless supply or distribution of electric power
    • H02J50/80—Circuit arrangements or systems for wireless supply or distribution of electric power involving the exchange of data, concerning supply or distribution of electric power, between transmitting devices and receiving devices
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J7/00—Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
    • H02J7/00032—Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries characterised by data exchange
    • H02J7/00034—Charger exchanging data with an electronic device, i.e. telephone, whose internal battery is under charge
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04B—TRANSMISSION
    • H04B13/00—Transmission systems characterised by the medium used for transmission, not provided for in groups H04B3/00 - H04B11/00
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04B—TRANSMISSION
    • H04B7/00—Radio transmission systems, i.e. using radiation field
    • H04B7/24—Radio transmission systems, i.e. using radiation field for communication between two or more posts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40—Animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0204—Operational features of power management
    • A61B2560/0214—Operational features of power management of power generation or supply
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J2310/00—The network for supplying or distributing electric power characterised by its spatial reach or by the load
    • H02J2310/10—The network having a local or delimited stationary reach
    • H02J2310/20—The network being internal to a load
    • H02J2310/23—The load being a medical device, a medical implant, or a life supporting device

Definitions

  • the present invention relates to an apparatus, a system and a method for acquiring a biological signal of a laboratory animal, and more particularly, to an apparatus, a system and a method for acquiring a biological signal from a laboratory animal using magnetic field communication and wireless power transmission.
  • a wireless power transmission technology for transmitting energy wirelessly As a wireless power transmission technology for transmitting energy wirelessly, a wireless power transmission system using a magnetic induction phenomenon is used.
  • the magnetic induction method of inducing current through a magnetic field from one coil to another is very sensitive to the distance and relative position between the coils, so that the transmission efficiency drops rapidly even if the distance between the two coils is slightly dropped or twisted. Accordingly, such a magnetic induction wireless power transmission system has a weak point that can be used only in the short distance of several cm or less.
  • US Patent 7,741,735 discloses a non-radiative energy transfer method based on the attenuation wave coupling of the resonant field. This is because two resonators with the same frequency do not affect other non-resonators around them, but they tend to couple with each other and are introduced as a technology that can transfer energy over a long distance compared to conventional electromagnetic induction. .
  • an apparatus and method for acquiring an animal's biosignal have been used in animal experiments used in various academic fields.
  • a device for measuring the biosignal is mounted on the body of the animal, and the biosignal is received from the apparatus.
  • devices mounted on an animal's body generally use RF wireless communication for measurement and signal transmission.
  • the power efficiency of the RF wireless communication is not high enough to increase the power consumption of the overall system as well as to reduce the data transmission rate. This requires not only to attach the battery to the device mounted on the animal body, but also to replace the attached battery frequently.
  • the present invention has been made in the technical background as described above, and an object thereof is to provide an apparatus, a system, and a method for acquiring a biological signal from a laboratory animal using magnetic field communication and wireless power transmission.
  • Apparatus for acquiring a biological signal from a laboratory animal a transmission and reception antenna; A power control unit for converting power transmitted from an external wireless power transmission apparatus through the transmission / reception antenna; A sensor that operates by using the power supplied from the power control unit and detects a biological signal of a laboratory animal; A signal processor connected to the sensor and processing the bio-signals sensed by the sensor; And a wireless communication unit for communicating with an external device using the transmission / reception antenna.
  • the wireless communication unit may include a first communication unit communicating with the wireless power transmission apparatus in a magnetic field; And a second communication unit configured to wirelessly communicate with an external wireless data reception and analysis system, wherein the apparatus for acquiring the biological signal of the laboratory animal may further include a stimulation generator for applying a stimulus to the laboratory animal to obtain the biological signal. It may be.
  • a method of acquiring a biological signal of a laboratory animal comprising: receiving wireless power from an external wireless power transmission device; Operating a sensor that senses a biological signal of a laboratory animal using the received wireless power; Detecting a biological signal of a laboratory animal by the sensor; Processing the detected biosignal; And transmitting the biosignal.
  • the bio-signal is preferably transmitted to the wireless data receiving and analysis system outside the sensor through magnetic field communication or ultra-high frequency radio frequency recognition.
  • a biological signal acquisition system of a laboratory animal includes a wireless power transmission device for transmitting power wirelessly using a magnetic field;
  • a biological signal acquisition device for an experimental animal which operates using power received from the wireless power transmission device and includes a sensor for sensing a biological signal of the laboratory animal;
  • a wireless data receiving and analyzing system for wirelessly receiving the biological signal detected from the biological signal obtaining apparatus.
  • the wireless power transmission device may be embedded in a cage in which a laboratory animal equipped with the biological signal acquisition device is placed.
  • the apparatus for acquiring a biological signal of a laboratory animal of the present invention receives power required for sensor operation and communication using a magnetic field from an external wireless power supply device, and thus may operate without a separate battery. Accordingly, it can be used for long-term experiments without inconvenience due to frequent replacement of the battery, and is particularly advantageous when the biosignal obtaining apparatus is inserted into the laboratory animal body.
  • FIG. 1 is a block diagram showing the overall configuration of a wireless power transmission-based biosignal acquisition system according to an embodiment of the present invention.
  • FIG 2 illustrates a physical layer structure of magnetic field communication (MFAN) used in a wireless power transmission-based biosignal acquisition system according to an embodiment of the present invention.
  • MFAN magnetic field communication
  • FIG. 3 shows a super frame structure of a medium access control layer of MFAN.
  • 4 is a state diagram of the MFAN coordinator.
  • 5 is a state diagram of an MFAN node.
  • FIG. 6 is a block diagram illustrating a configuration of a wireless power transmission apparatus of a wireless power transmission based biosignal acquisition system according to an embodiment of the present invention.
  • FIG. 7 is a block diagram illustrating a configuration of an apparatus for obtaining biometric information of a system for acquiring a wireless power transmission based biosignal according to an embodiment of the present invention.
  • FIG. 8 is a block diagram illustrating a configuration of a wireless data receiving and analyzing system of a wireless power transmission based biosignal obtaining system according to an exemplary embodiment of the present invention.
  • FIG. 9 is a flowchart illustrating a method of acquiring a biological signal of a laboratory animal in a wireless power transmission-based biological signal acquisition system according to an embodiment of the present invention.
  • FIG. 1 is a block diagram showing the overall configuration of a wireless power transmission-based biosignal acquisition system according to an embodiment of the present invention.
  • the biological signal acquisition system of a laboratory animal is separated from the biological signal acquisition device 200 mounted on the laboratory animal by a predetermined distance from the biological signal acquisition device 200.
  • Located in the place is configured to include a wireless power transmission apparatus 100 for transmitting power wirelessly using a magnetic field.
  • the biological signal acquisition system of a laboratory animal includes a wireless data reception and analysis system 300 for analyzing the obtained biological signal
  • the wireless data reception and analysis system 300 is a biological signal
  • the biosignal is wirelessly received from the acquisition apparatus 200.
  • the wireless power transmitter 100 may transmit wireless power to the biosignal obtaining apparatus 200, and may exchange information with the biosignal obtaining apparatus 200 using magnetic field communication (MFAN). . That is, the biosignal acquisition apparatus 200 may receive information of the biosignal acquisition apparatus 200 including identification information, type, location, or state of charge of the biosignal acquisition apparatus 200, and transmit wireless power to the biosignal acquisition apparatus 200. This information can be used when doing so.
  • MFAN magnetic field communication
  • the MFAN technology is used in conjunction with a technology that transmits power wirelessly to a biometric signal acquisition device, which has a high permeability in any environment, a communication distance loss compensation when a sensor tag is inserted into a living body, and a wireless power transmission device.
  • the MFAN system is a wireless communication system using a magnetic field region. Since the MFAN system is a wireless communication based on energy transmission, power transmission is possible at the same time as data transmission.
  • the wireless power transmission apparatus 100 is a coordinator of the MFAN
  • the biological signal acquisition device 200 is a node of the MFAN.
  • the 2 shows a physical layer structure of MFAN. It consists of preamble, header and payload.
  • the preamble includes a wakeup signal and a sync signal.
  • the header includes a data rate, a coding method, a payload length, and an error check code.
  • the wake-up signal is included only when the coordinator sends data to the nodes. The nodes are in a sleep state when not in data communication, and then wake up from the point where the coordinator sends data to start communication.
  • the MFAN system is a communication method capable of simultaneously transmitting data and transmitting power in extreme environments with respect to radio waves around water and soil, the MFAN system transmits power and transmits and receives data to and from a biological signal acquisition device 200 mounted inside a living body of a laboratory animal. It is a suitable communication and power transmission system.
  • FIG. 3 shows a super frame structure of a medium access control layer of MFAN.
  • One super frame is divided into a request section, a response section, and a spontaneous section.
  • a coordinator sends a request packet to a node in the request section
  • the node sends the requested data to the coordinator.
  • the spontaneous section the node can send data arbitrarily without request of the coordinator.
  • the spontaneous section can send data randomly.
  • the coordinator schedules the power transmission based on the received information, and transmits the power transmission scheduling information to the nodes through the request packet in the next super frame, and then transmits power to each node in the response period.
  • FIG. 4 is a state diagram of the MFAN coordinator
  • FIG. 5 is a state diagram of the MFAN node.
  • the coordinator performs data transmission and wireless power transmission while switching between standby and packet analysis, packet generation, and power transmission.
  • the node transmits data to and from the sleep, active, standby, packet analysis, packet generation, power blocking, power transmission, sleep packet analysis, and sleep packet generation states. Do this.
  • Wireless power transmission is a technology using a phenomenon that energy is transferred by attenuation wave coupling when the frequency between the transmission and reception coils in the near magnetic field resonates.
  • Magnetic resonance technology which can transmit power wirelessly from tens of centimeters to several meters, has a very high degree of directional freedom of the transmitting and receiving coils, which can transmit and receive power regardless of location within a near field. It also transmits power only to materials with the same frequency, so there is little impact from other devices located between the charging system and the charger.
  • a single transmitting coil can be used to transmit power to a plurality of chargers.
  • the battery-less biosignal acquisition apparatus 200 is supplied by supplying power from the wireless power transmission apparatus 100 to the biosignal acquisition apparatus 200 using the above-described self-resonant wireless power transmission. ) Can be implemented.
  • the wireless power transmission apparatus 100 may be implemented in a fixed or mobile type, and may be embedded in a cage of a laboratory animal.
  • the biological signal obtaining apparatus 200 may be attached to the outside of the laboratory animal or inserted into the inside of the living body.
  • a repeater may be used to extend the transmission distance of wireless power or for other purposes.
  • the repeater may be composed of a communication and power repeater that relays both data and power, Considering that the communication range is wider than the power transmission range, only power can be relayed.
  • the wireless data receiving and analyzing system 300 wirelessly receives the biosignal obtained by the biosignal obtaining apparatus 200 and analyzes the biosignal wirelessly in a method as necessary.
  • the communication method between the wireless data reception and analysis system 300 and the biosignal acquisition apparatus 200 is not particularly limited, and the contents and methods of the analysis also depend on the characteristics of the received biosignal or the purpose of analyzing the received biosignal. There is no particular limitation according to the present invention.
  • biosignal acquisition apparatus 200 mounted on one laboratory animal is illustrated in FIG. 1, two or more biosignal acquisition apparatuses 200 are mounted on one laboratory animal, or the biosignal acquisition apparatus 200 is illustrated in FIG. 1.
  • wireless power may be transmitted to the plurality of biosignal acquisition apparatuses 200 using one wireless power transmission apparatus 100, and the wireless data reception and analysis system 300 may also include the plurality of biosignal acquisition apparatuses 200.
  • data can be received and processed by wireless communication.
  • FIG. 6 is a block diagram illustrating a configuration of a wireless power transmission apparatus of a wireless power transmission based biosignal acquisition system according to an embodiment of the present invention.
  • the wireless power transmitter 100 transmits wireless power to the biosignal obtaining apparatus 200 and wireless power for transmitting and receiving data to and from the biosignal obtaining apparatus 200.
  • the matching network 140 and the biosignal obtaining apparatus 200 which transmits power from the apparatus 200 to the biosignal obtaining apparatus 200 and frequency matching to transmit and receive data between the wireless power transmitter 100 and the biosignal obtaining apparatus 200.
  • RF power amplifier 120 to amplify the signal received from the, data interworking software 160 for data interworking with the biological signal acquisition device 200 and for data processing And a data processor 150.
  • FIG. 7 is a block diagram illustrating a configuration of an apparatus 200 for obtaining biometric information of a system for acquiring a wireless power transmission based biosignal according to an embodiment of the present invention.
  • the apparatus 200 for obtaining biometric information of a laboratory animal receives wireless power from the wireless power transmission apparatus 100, and the wireless power transmission apparatus 100 and the wireless data reception and analysis system 300.
  • RF transceiver 260 for transmitting and receiving data and data
  • a power control module 210 for converting the received power to be suitable for use in the sensor 240
  • Sensor 270 and sensor interface 230 for acquiring biometric information of the device
  • the apparatus 200 for obtaining biological information of a laboratory animal receives power from the wireless power transmission apparatus 100, operates the sensor 270 using the received power, processes a signal, and transmits the signal. There is no need for a separate battery to power other modules including the sensor 270.
  • the senor 270 may further include components for stimulating to obtain a biological signal.
  • each component of the biometric information acquisition device 200 can be configured as a single chip for convenient mounting on the body of the laboratory animal, and the tag can stably data without damaging the laboratory animal in vivo. It is preferable to use a packaging technique using a biocompatible material for transmitting the.
  • FIG. 8 is a block diagram illustrating a configuration of a wireless data reception and analysis system 300 of a wireless power transmission based biosignal acquisition system according to an exemplary embodiment of the present invention.
  • the wireless data receiving and analyzing system 300 includes a data receiving module 310 for receiving data from the biometric information obtaining apparatus 200 and data for processing the received data.
  • a processing module 320 an analysis module 330 for analyzing data, and a monitoring system 340.
  • the wireless data reception and analysis system 300 is a radio that is commonly used except for wirelessly receiving data from the biometric information acquisition device 200 according to the embodiment of the present invention. Since the data receiving and analyzing system 300 is similar, detailed description thereof will be omitted.
  • the above-described magnetic field communication method may be used for wireless communication between the biometric information acquisition device 200 and the wireless data reception and analysis system 300, but is not limited thereto, and other wireless communication such as UHF RFID technology. The method may be used.
  • FIG. 9 is a flowchart illustrating a method of acquiring a biological signal of a laboratory animal in a wireless power transmission-based biological signal acquisition system according to an embodiment of the present invention.
  • the sensor 270 of the biometric information acquisition device 200 starts to operate (S320).
  • power is transmitted from the wireless power transmission device 100 to the biometric information acquisition device 200.

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  • Engineering & Computer Science (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Power Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Signal Processing (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Arrangements For Transmission Of Measured Signals (AREA)

Abstract

Dans la présente invention, de la puissance sans fil est fournie au moyen d'un champ électromagnétique pour faire fonctionner un capteur installé sur un animal de laboratoire, et un signal détecté par le capteur est transmis à un système d'analyse de données par le biais d'une communication par champ électromagnétique. Un appareil permettant d'obtenir des signaux biologiques provenant d'un animal de laboratoire, selon la présente invention, comprend: une antenne d'émission/réception; une unité de commande de puissance servant à convertir la puissance qui est délivrée à partir d'un dispositif de transmission de puissance sans fil externe par l'intermédiaire de l'antenne d'émission et de réception; un capteur qui fonctionne au moyen de l'énergie fournie par l'unité de commande de puissance pour détecter des signaux biologiques de l'animal de laboratoire; une unité de traitement de signal qui est reliée au capteur pour traiter les signaux biologiques détectés par le capteur; et une unité de communication sans fil servant à communiquer avec le dispositif externe au moyen de l'antenne d'émission et de réception.
PCT/KR2012/011644 2012-11-26 2012-12-27 Appareil, système et procédé permettant d'obtenir des signaux biologiques provenant d'animaux de laboratoire WO2014081071A1 (fr)

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KR1020120134482A KR101409844B1 (ko) 2012-11-26 2012-11-26 실험용 동물의 생체 신호 획득 장치, 시스템 및 방법
KR10-2012-0134482 2012-11-26

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EP3267555A4 (fr) * 2015-03-06 2018-01-10 Samsung Electronics Co., Ltd. Dispositif électronique pilotant un capteur non alimenté, et son procédé de commande
US10658880B2 (en) 2015-03-06 2020-05-19 Samsung Electronics Co., Ltd. Electronic device for operating powerless sensor and control method thereof
CN113082514A (zh) * 2021-03-29 2021-07-09 天津工业大学 一种基于无线充电的生物电磁治疗装置的自适应调节方法

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KR101638605B1 (ko) * 2014-11-28 2016-07-11 기초과학연구원 실험체의 인지기능 실험장치 및 실험방법
KR20180032254A (ko) * 2016-09-21 2018-03-30 주식회사 웨어롬 생체신호 측정장치
KR102303540B1 (ko) * 2021-07-02 2021-09-23 한국과학기술원 실험동물의 다중 감각정보 인지기능 측정 장치 및 방법
KR20230025284A (ko) 2021-08-13 2023-02-21 주식회사 에스비솔루션 다크 모드 여기를 이용하여 생체 정보를 측정하는 안테나 장치

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US10658880B2 (en) 2015-03-06 2020-05-19 Samsung Electronics Co., Ltd. Electronic device for operating powerless sensor and control method thereof
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CN113082514B (zh) * 2021-03-29 2023-09-26 天津工业大学 一种基于无线充电的生物电磁治疗装置的自适应调节方法

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