WO2014065640A3 - 외톨개모자반 추출물 또는 이의 분획물을 유효성분으로 함유하는 염증성 질환 치료 또는 예방용 조성물 - Google Patents

외톨개모자반 추출물 또는 이의 분획물을 유효성분으로 함유하는 염증성 질환 치료 또는 예방용 조성물 Download PDF

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Publication number
WO2014065640A3
WO2014065640A3 PCT/KR2013/009640 KR2013009640W WO2014065640A3 WO 2014065640 A3 WO2014065640 A3 WO 2014065640A3 KR 2013009640 W KR2013009640 W KR 2013009640W WO 2014065640 A3 WO2014065640 A3 WO 2014065640A3
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WIPO (PCT)
Prior art keywords
extract
fraction
inflammatory diseases
treating
composition
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Application number
PCT/KR2013/009640
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English (en)
French (fr)
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WO2014065640A2 (ko
Inventor
김형락
정은지
김성희
김치현
양종순
김재일
이민섭
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부경대학교 산학협력단
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Publication of WO2014065640A2 publication Critical patent/WO2014065640A2/ko
Publication of WO2014065640A3 publication Critical patent/WO2014065640A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

본 발명은 염증성 질환 치료 또는 예방용 조성물에 관한 것으로, 외톨개모자반(Myagropsis myagroides) 추출물 또는 상기 추출물의 분획물을 유효성분으로 함유하는 염증성 질환의 예방 또는 치료용 약학적 조성물을 제공한다. 본 발명의 외톨개모자반 추출물 또는 이의 분획물은 종래 알려진 푸코잔틴(fucoxanthin)이 전혀 함유되어 있지 않음에도 일산화질소(NO), 프로스타글란딘 E2(prostaglandin E2, PGE2) 및 염증성 사이토카인의 생성을 억제할 뿐만 아니라 iNOS 및 COX-2의 발현을 효과적으로 억제하는 효과가 있는 바, 염증성 질환의 예방 및 치료에 유용하게 이용될 수 있다.
PCT/KR2013/009640 2012-10-08 2013-10-28 외톨개모자반 추출물 또는 이의 분획물을 유효성분으로 함유하는 염증성 질환 치료 또는 예방용 조성물 WO2014065640A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20120111363A KR101487065B1 (ko) 2012-10-08 2012-10-08 외톨개모자반 추출물 또는 이의 분획물을 유효성분으로 함유하는 염증성 질환 치료 또는 예방용 조성물
KR10-2012-0111363 2012-10-28

Publications (2)

Publication Number Publication Date
WO2014065640A2 WO2014065640A2 (ko) 2014-05-01
WO2014065640A3 true WO2014065640A3 (ko) 2014-06-05

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PCT/KR2013/009640 WO2014065640A2 (ko) 2012-10-08 2013-10-28 외톨개모자반 추출물 또는 이의 분획물을 유효성분으로 함유하는 염증성 질환 치료 또는 예방용 조성물

Country Status (2)

Country Link
KR (1) KR101487065B1 (ko)
WO (1) WO2014065640A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101784557B1 (ko) * 2015-07-29 2017-10-12 부경대학교 산학협력단 외톨개 모자반 추출물 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 아토피 예방 또는 개선용 조성물
KR101964580B1 (ko) 2018-01-25 2019-04-02 주식회사 웰파이토 더덕 추출물 또는 이의 분획물을 포함하는 항염증용 조성물 또는 천식 예방 또는 치료용 조성물
KR102072907B1 (ko) 2018-04-02 2020-02-04 주식회사 웰파이토 더덕 추출물 또는 이의 분획물을 포함하는 항염증용 조성물 또는 천식 예방 또는 치료용 조성물

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09268119A (ja) * 1996-04-03 1997-10-14 Lion Corp 皮膚外用剤
KR20040099601A (ko) * 2003-05-19 2004-12-02 라이브켐 주식회사 베타-아밀로이드에 의한 신경독성 억제용 조성물 및 이를이용한 억제방법
KR100873180B1 (ko) * 2007-11-05 2008-12-10 신라대학교 산학협력단 갈조류 추출물을 포함하는 항균 조성물
JP2009051791A (ja) * 2007-08-29 2009-03-12 Hokkaido Univ 生理活性物質を濃縮した海藻由来製品素材及びその製造方法及び海藻由来製品
JP2012001527A (ja) * 2010-05-17 2012-01-05 Kao Corp 皮膚外用剤

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09268119A (ja) * 1996-04-03 1997-10-14 Lion Corp 皮膚外用剤
KR20040099601A (ko) * 2003-05-19 2004-12-02 라이브켐 주식회사 베타-아밀로이드에 의한 신경독성 억제용 조성물 및 이를이용한 억제방법
JP2009051791A (ja) * 2007-08-29 2009-03-12 Hokkaido Univ 生理活性物質を濃縮した海藻由来製品素材及びその製造方法及び海藻由来製品
KR100873180B1 (ko) * 2007-11-05 2008-12-10 신라대학교 산학협력단 갈조류 추출물을 포함하는 항균 조성물
JP2012001527A (ja) * 2010-05-17 2012-01-05 Kao Corp 皮膚外用剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HEO, SOO-JIN ET AL.: "Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages", FOOD AND CHEMICAL TOXICOLOGY, vol. 48, 2010, pages 2045 - 2051 *
JOUNG, EUN-JI ET AL.: "Anti-inflammatory effect of ethanolic extract from Myagropsis myagroides on murine macrophages and mouse ear edema", BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, vol. 12, 3 October 2012 (2012-10-03), pages 171 *

Also Published As

Publication number Publication date
KR101487065B1 (ko) 2015-01-27
KR20140045161A (ko) 2014-04-16
WO2014065640A2 (ko) 2014-05-01

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