WO2013182870A1 - Module d'alimentation et procédé de fourniture d'un mélange d'une ou plusieurs poudres à un récipient de réception - Google Patents

Module d'alimentation et procédé de fourniture d'un mélange d'une ou plusieurs poudres à un récipient de réception Download PDF

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Publication number
WO2013182870A1
WO2013182870A1 PCT/IB2012/052804 IB2012052804W WO2013182870A1 WO 2013182870 A1 WO2013182870 A1 WO 2013182870A1 IB 2012052804 W IB2012052804 W IB 2012052804W WO 2013182870 A1 WO2013182870 A1 WO 2013182870A1
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WO
WIPO (PCT)
Prior art keywords
feeder
units
receiving container
module
storage hopper
Prior art date
Application number
PCT/IB2012/052804
Other languages
English (en)
Inventor
Bart Peter VERHOEST
Alexander Clemens Henricus Josef Schaepman
Johannes Adrianus Jozef Maria VUGTS
Original Assignee
Gea Process Engineering Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gea Process Engineering Nv filed Critical Gea Process Engineering Nv
Priority to PCT/IB2012/052804 priority Critical patent/WO2013182870A1/fr
Publication of WO2013182870A1 publication Critical patent/WO2013182870A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01G—WEIGHING
    • G01G19/00—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups
    • G01G19/22—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups for apportioning materials by weighing prior to mixing them
    • G01G19/32—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups for apportioning materials by weighing prior to mixing them using two or more weighing apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/60—Mixing solids with solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/84—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins
    • B01F33/841—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins with component receptacles fixed in a circular configuration on a horizontal table, e.g. the table being able to be indexed about a vertical axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/71775—Feed mechanisms characterised by the means for feeding the components to the mixer using helical screws
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/88—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise
    • B01F35/881—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise by weighing, e.g. with automatic discharge
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01G—WEIGHING
    • G01G19/00—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups
    • G01G19/387—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups for combinatorial weighing, i.e. selecting a combination of articles whose total weight or number is closest to a desired value
    • G01G19/393—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups for combinatorial weighing, i.e. selecting a combination of articles whose total weight or number is closest to a desired value using two or more weighing units

Definitions

  • the present invention relates to a feeder module comprising a number of storage hoppers adapted to contain material to be processed, weighing means, conveying means for transporting the material from the storage hoppers to at least one receiving container, the feeder module comprising a plu- rality of feeder units.
  • the invention furthermore relates to a method for providing a very accurately dosed mixture of one or more powders to a receiving container.
  • Typical manufacturing processes hitherto employed within the pharmaceutical field are of a batch nature. Batch manufacturing processes have a number of advantages and provide satisfactory results within many areas.
  • the level of quality of monitoring and control attainable by a batch process is often not sufficient, i.a. due to the fact that settings are fixed.
  • a relatively large buffer volume is required, entailing undesired back-mixing of the material stream.
  • manufacturers' and customers' focus of interest has shifted to continuous processes, in which settings may be varied and are allowed to change within a design space.
  • Some examples of continuous processes have been devised in the prior art, for instance in EP 0 275 834 A1 , in which two or more ingredients are fed into the process line at various feed or inlet points, and the ingredients are mixed, dried and subsequently compacted in a conventional tabletting machine.
  • the process line includes a first mixing unit, a drying unit, a sizing unit and a second mixing unit.
  • the output corresponds to the aggregated input of ingredients at the feed or inlet points, i.e. all of the material is fed to the manufacturing machine in a continuous flow and at a constant rate. Due to a variety of fac- tors, this is not feasible in practice. First, it is under any circumstances almost impossible to adjust the output from the mixing and drying units to provide a just-in-time supply of material to the tabletting machine. Second, the continuous production of tablets of a desired high level of quality requires careful monitoring, controlling and adjustment of process parameters in order to avoid a large rejection number from the tabletting machine. This may lead to accumulation of material along the process line awaiting adjustment of certain process parameters. In turn, this inevitably necessitates the use of intermediate buffer vessels in order to store material upstream of the tablet press.
  • WO 2010/128359 (GEA Pharma Systems), a contained module being able to operate by a fully continuous process for the production of tablets is devised.
  • all units of the tabletting process may be contained, thus reducing the risk of operator exposure and facilitating operation of the tablet press, as all preparations of the material stream fed to the tablet press are carried out in a contained and controlled manner.
  • the term "contained" is defined by its level of containment according to suitable measurements, and is defined as at least dust-tight.
  • the mixing unit refers to a unit operation generally capable of mixing or otherwise processing one, two or more components into a desired form.
  • the mixing unit may thus also be capable of modifying the physical form of dry component(s) processed in the mixing unit, e.g. a feed stream of powder(s) may be converted to a granulate comprising the component(s).
  • the mixing unit may be a granulator for making a granulate from dry powders, such as a granulator to which a granulating liquid is added, or a roller compactor. Further examples include a twin screw blender and a twin screw granulator.
  • the mixing unit may include such equipment as a dryer, a dry blender, a continuous dry blender or the like.
  • Dispensing or dosing the component(s) to the mixing unit, or to a receiving container upstream of the mixing unit most often takes place from storage hoppers connected to feeders which in turn supply the mixing unit or receiving container with the desired amount of powder(s) or other components).
  • Feeding of powders is carried out by means of screw conveyors according to one of two main solutions: volumetric feeding or gravimetric feed- ing.
  • volumetric feeding material held in a hopper is fed into a process at a constant volume per unit of time
  • gravimetric feeding material is fed into a process at a constant weight per unit of time. The weight is measured by a weighing cell.
  • Gravimetric feeders may operate on the loss-in- weight principle, which provides for more accurate dosing than feeders oper- ating on other principles.
  • EP 290 999 B1 One example of prior art concerned with achieving an increased ac- curacy when feeding powders is EP 290 999 B1 , in which powders are fed from storage hoppers to a weighing hopper and further to a mixing or preparation container.
  • each feeder unit includes a storage hopper, a weighing cell, a conveyer, and a discharge end, and that said plurality of feeder units comprises more than four feeder units arranged in a single level to discharge into a common receiving container.
  • each feeder unit of the feeder module is able to dispense a very accurately measured amount of material into one common receiving container.
  • the configuration of the feeder units in a single level i.e. on the same horizontal plane, entails a number of advantages.
  • the accuracy and quality are improved, as the weighing signal and thereby the mass flow of the feeder units are not affected.
  • the invention is i.a. based on the recognition that an increased accuracy and thereby quality is achieved when the materials involved are not only dispensed into one and the same receiving container but also at a specific point in time and space.
  • each feeder unit extending radially outwards from an imaginary inner circle defined at the discharge end adapted to face the common receiving container to an imaginary outer circle defined by radially opposite end of each feeder unit, the feeder units being positioned substantially on radii extending from the imaginary inner circle.
  • the feeder module comprises five feeder units and the diameter of the imaginary inner circle is 42 - 100 mm.
  • the feeder module may comprise six feeder units and the diameter of the imaginary inner circle is 50-1 120 mm.
  • the feeder module comprises eight feeder units and the diameter of the imaginary inner circle is 65-150 mm.lt turns out that the accuracy of the feeder module is highly dependent on the dead weight on the scale of the feeder unit, and in particular to the ratio between the dead weight of each feeder unit and the net weight of the powder received in the storage hopper. Furthermore, the response time depends on this ratio as well. The ratio of powder weight and the maximum mass flow provides the maximum run time to empty a feeder or the maximum refill interval in hours.
  • the arithmetic product of the maximum refilling interval [h] and the dead weight [kg] of each feeder unit is below 0.1 kgh. If the powder density is taken out of the equation the maximum refilling interval is also the ratio of the hopper volume [L] and the feed rate [L/h]. For instance, the capacity of the storage hopper of each feeder unit may be less than 1 .6 liters. The maximum flow rate may for instance be 100 L/h. The maximum refilling interval is then 0.016 h. The dead weight is typically 5 kg.
  • the arithmetic product of the dead weight and the maximum refilling interval 0.016 h is 0.087 kgh.
  • the arithmetic product may be below 0.2, preferably below 0.1 , most preferred below 0.05 kgh.
  • the very sensitive scale takes a limited amount of powder but is more accurate.
  • each feeding unit In order to allow for detachment of parts of each feeding unit relative to other parts, it is advantageous that the storage hopper, the conveyer and the discharge end of each feeder unit are releasably connected to the weighing cell.
  • the powder may in principle be transported or pumped from the storage hopper to the receiving container in any suitable manner.
  • the conveyer is a twin screw conveyor.
  • At least one, preferably both, of the screws of the twin screw conveyor has a variable pitch along its length underneath the storage hopper.
  • At least one, preferably both, of the screws has a variable diameter along its length underneath the storage hopper.
  • the variable diameter assures that the whole length of at least one screw, or of both screws, under the hopper is evenly loaded and hereby creating an even transport volume over the section of the hopper.
  • a method for providing a mixture of one or more powders in a receiving container comprising the steps of:
  • the kind of material to be filled into the storage hoppers of the indi- vidual feeder units is typically powder.
  • two or more different types of powder are filled into the individual feeder units.
  • each powder is a single component powder, rather than a pre-blended powder containing two or more components, as the latter has a tendency to segregate.
  • any two feeder units may be filled with the same powder such that in the case of 6 feeder units in the feeding module, three different powders may be charged into the receiving container and to further processing in the process line. Refilling of the storage hoppers may take place intermittently and possibly such that one feeder unit is filled when there is still powder in the other one of a pair.
  • Fig. 1 shows a perspective view of an embodiment of a feeder module of the invention
  • Fig. 2 shows a plan view of the feeder module of Fig. 1 ;
  • Fig. 2a shows a schematic overview corresponding to Fig. 2, in an embodiment comprising eight feeder units;
  • Fig. 2b shows a schematic overview corresponding to Fig. 2a, of another embodiment comprising seven feeder units;
  • Fig. 2c shows a schematic overview corresponding to Fig. 2a, of further embodiment comprising six feeder units;
  • Fig. 2d shows a schematic overview corresponding to Fig. 2a, of further embodiment comprising five feeder units;
  • Fig. 3 shows a sectional view of the feeder module of Fig. 1 ;
  • Fig. 4 shows a detail cross section of the receiving hopper or receiving container
  • Figs 5 and 6 show a plan view of a feeder module of another embodiment in two different conditions
  • Fig. 7 shows a perspective view of a detail of an embodiment of a feeder module and containment of powder contacting powder pump according to the invention
  • Figs 8a-c show a side view of a detail of a pre-feeder element of a feeder module according to the invention
  • Figs 9a-9c show a perspective view of an embodiment of a feeder module, a view from above of a feeder unit and a more detailed perspective view of an embodiment of a feeder module according to the invention.
  • Figs 10 and 1 1 show plan views of a detail of two different embodiments of a feeder module according to the invention. Detailed description of the invention and of preferred embodiments
  • a feeder module generally designated
  • the feeder module 1 comprises a plurality of feeder units 2.
  • Each feeder unit 2 comprises a feeder part 20 and a weighing cell.
  • a pre-feeder element 40 is attached to the feeder part 20.
  • Figs 1 to 3 there are eight such feeder units 2.
  • the feeder module comprises five feeder units 2 and the diameter of the imaginary inner circle is
  • the feeder module may comprise six feeder units and the diameter of the imaginary inner circle is 50-120 mm for a twin screw discharge tube of 24 to 45 mm and a lateral clearance (CL) in between two twin screw discharge tubes of 1 to 10 mm. See Fig. 2c.
  • the feeder module comprises seven feeder units and the diameter of the imaginary inner circle is 57-140 mm for a twin screw discharge tube of 24 to 45mm and a lateral clearance (CL) in between two twin screw discharge tubes of 1 to 10 mm, see Fig. 2b.
  • the feeder module comprises eight feeder units and the diameter of the imaginary inner circle is 65- 150 mm for a twin screw discharge tube of 24 to 45 mm and a lateral clearance in between two twin screw discharge tubes of 1 to 10 mm, see Fig. 2a.
  • each feeder unit 2 includes a storage hopper 21 to contain material to be processed, a conveyer 22, a discharge end 23, and a weighing cell 24.
  • the conveyer 22 has the function of transporting the material from the storage hopper 21 to discharge the material into a receiving container in a manner to be described in further detail below. Furthermore, it emerges from these Figures that the feeder units 2 are arranged in a single level to discharge into a common receiving container 3.
  • the feeder units 2 are distributed substantially evenly over 360° in the same level, i.e. on substantially the same horizontal plane.
  • the feeder units 2 are arranged in a spokes- like configuration, each feeder unit 2 extending radially outwards from an imaginary inner circle 31 defined at the discharge end 23 facing the common receiving container 3 to an imaginary outer circle defined by radially opposite end of each feeder unit.
  • the feeder units 2 are positioned substantially on radii extending from the imaginary inner circle.
  • the smallest possible dimension of the imaginary inner circle 31 depends on the number of feeder units 2 and of the physical dimensions of the individual feeder units 2. Typical values in embodiments comprising five feeder units, possibly distributed substantially evenly, are a diameter of the imaginary inner circle of 42-100 mm. In an embodiment comprising six feeder units, possibly distributed substantially evenly, the diameter of the imaginary inner circle is typically 50-120 mm. 7 feeders 57-140 mm. In the embodiment shown in Figs 1 to 4, where eight feeder units 2 are adapted to be distributed substantially evenly, the diameter of the imaginary inner circle is typically 65 to 150 mm, in the specific embodiment approximately 107 mm. These values are dependent also on the desired clearance of 1 -10 mm between parts of neighbouring feeder units and the dimensions of the individual parts. In the embodiment shown, the ap- proximate width 26 of the discharge tube of each feeder unit 2 is 40 mm.
  • the dimensioning of the feeder units 2 of the feeder module 1 depends on the field of application. Sizing may for instance be available as a range, such that each feeder unit 2 in a module 1 is of a different size.
  • the dead weight of each feeder unit 2 is below 5 kg, and the capacity of the storage hopper of each feeder unit is less than 2 liters.
  • the net weight of the powder to be filled into the storage hopper 21 of the individual feeder units 2 depend on the volume but also on the kind of powder applied.
  • the maximum volume of powder in the storage hopper lies in the interval 1 .6 to 2 liters.
  • the maximum mass flow rate is approximately 50 kg/h.
  • the ratio of powder weight and the maximum mass flow provide a maximum run time to empty a feeder or a maximum refilling interval pr. hour.
  • the arithmetic product of the maximum refilling interval [h] and the dead weight [kg] of each feeder unit 2 is below 0.1 kgh. If the powder density is taken out of the equation and replaced by volume the maximum refilling interval is also the ratio of the hopper volume [L] and the federate [L/h]. E.g the capacity of the storage hopper of each feeder unit is less than 1 .6 liters. The maximum flow rate is 100 L/h. The maximum refill interval is then 0.016h.
  • the dead weight of each feeder unit 2 is typically 5 kg.
  • the arithmetic product of the dead weight 5 kg and the maximum refill interval 0.016h is 0.087kgh.
  • the arithmetic product is typically below 0.2, preferably below 0.1 , most preferably below 0.05 kgh.
  • the storage hopper, the conveyer and the discharge end of each feeder unit are releasably connected to the weighing cell.
  • Fig. 4 shows a detail cross section of the receiving hopper or receiving container 3.
  • the discharge tube end 23 of the feeder units 2 with the imaginary circle 31 is smaller than the diameter of the receiving container 3.
  • the discharged powder falls straight into the throat of the receiving container 3 and is substantially not hooking up to the inner walls of the receiving container 3.
  • the configuration of the feeder units 2 of the feeder module is slightly different from that of Figs 1 to 4.
  • Detachment of one feeder unit 2, for instance for cleaning purposes, is carried out by detaching the feeder unit 2 from the re- ceiving container 3. This may take place in a contained manner, for instance by other tightening or sealing devices, such as by Layflat tubing (LFT).
  • LFT Layflat tubing
  • a casing 250 is provided around the storage hopper, the conveyer 22 and the discharge end 23 of each feeder.
  • the openings in the casing 250 are detached from the weighing cell.
  • the receiving container, which is also detached from the weighing cell, and the feeder part 20 are isolated in a contained way by means of a lay flat tube 260.
  • Lay flat tubes 260 are preferably made of a lightweight material having a very low stiffness, such that the weighing signal is left almost completely unaffected.
  • a lay flat tube 260 may also be provided between the storage hopper 21 and a pre-feeder element (see Fig. 1 ).
  • Refilling of the storage hoppers of the feeding units 2 may take place at different points in time, if expedient according to a predefined schedule.
  • the refilling takes place by means of a valve with air compensation, cf. part
  • Suitable valves are represented by plug valves, rotary dosing valves 41 , butterfly valves 42 and slide valves 43.
  • a level sensor 44 is provided for use when the weight is fluctuating during refill of the feeder unit 2. The refilling takes place in a contained manner so as to at least assure that no dust enters the surrounding environment by the use of an appropriate seal or tube.
  • the storage hopper 21 may be supplemented by a stirrer device 21 1 to break any bridges formed in the powder and to ensure that the conveyer 22 is fed properly.
  • the conveyer 22 is in the embodiment shown a twin screw conveyor.
  • the feeder unit 2 is additionally provided with lay flat tubing 260 and the receiving opening of the storage hopper 21 and at the discharge end 23.
  • both of the concave screws 221 and 222 of the twin screw conveyor 22 have a variable pitch along its length, a first pitch p1 and a second pitch p2, being different from the first pitch P1 .
  • the conveyer 22 is driven by a motor M.
  • the diameter of ach screw is constant.
  • the pitch of each screw is constant, whereas the diameter of the screws is variable along the length shown as diameter d1 and diameter d2. It is also possible to have one or more screws with both a variable pitch and a variable diameter.
  • the feeder module may comprise a number of additional features, such as analysis and control systems, loading and discharging stations etc.
  • the feeder unit of the feeder module has a storage hopper of a limited volume, a rapid or high frequency refilling system is provided.
  • feeders of a larger volume are refilled 4 to 8 times per hour.
  • the powder which is dropping into the storage hopper causes disturbances on the weight signal (due to the impact forces of the powder) over a period which is equal to the sum of the powder drop time and scale stabilization time. Together with the time of rolling average filters this usually takes 30 s up to 60 s to get a stable weighing signal after a refill or top-up.
  • the feeder is running in a volumetric mode.
  • the screw speed is defined by the Feed Factor curve, the feed factor being defined as the equivalent of the weight per screw revolution, and the accuracy depending on how good the curve is fitting to the reality.
  • Typical values of the refilling frequency of the feeder module according to the invention are one time per minute at a feed rate of 50 kg/h, i.e. mass flow 5 kg/h refill after 10 min. Due to its reduced weight and dynamic properties, the feeder module stabilizes in 2 to 4 seconds at a feed rate of 50 kg/h.
  • the principle underlying the refilling system of the feeder module according to the invention is different from others as it is based on refilling each time the same amount of power under the same conditions.
  • the refill system has either a weighing scale or a level sensor integrated combined with a volumetric dosing valve.
  • the system itself acts as a (pre)feeder and stores the number of impeller turns together with a level or a weight.
  • Such a refill or top-up system can also be used for material determination using the feeder data. Furthermore, it can be set to sense material variations. As the powder dosing valve always discharges in the center of the top-up tube, the shape of the powder stack is constant in the same area. During the powder drop, the powder at the bottom of the hopper is more compacted than the powder at the top of the hopper. However, the powder volume in the discharge tube is still not compacted. The screw speed remains unchanged until the fresh (i.e. more compacted) material is coming to the dis- charge opening. Each refill is reproducible and the system learns and converges to the optimal speed of the screws.
  • feeder data may be used to calculate theoretical compositions and confirm BU and Assay over specified time periods.
  • FFT fast Fourier Transform
  • the feeder module is subjected to a number of external and internal disturbances.
  • the disturbances normally include mechanical vibrations, wind load, bellow deformation forces etc. falling into one of two main types, viz. deterministic disturbances, which can be filtered, and non- deterministic disturbances, the effect of which must be reduced in other ways.
  • AVC Active Vibration Compensation
  • the feeder module according to the invention is dynamically more precise and faster responding compared to others. For instance, the recovery from non-cyclic external disturbances will only take about 2 to 4 seconds.
  • the method is intended for providing a mixture of one or more pow- ders in a receiving container as described in the above. Primarily, the method forms part of a process for processing pharmaceutical products, but may also be applied in other fields.
  • the desired plurality of feeder units is defined.
  • a receiving container is provided and is for instance connected to a granulator or to a tablet press.
  • the method may comprise the additional step of tabletting the mixture of the one or more powders.
  • the feeder units are arranged with the respective discharge ends facing the receiving container, and are connected thereto, in a single level.
  • the storage hopper of the respective feeder unit with a powder is filled with a suitable powder, and the powder from the respective storage hopper is fed to the receiving container to provide the mixture of the one or more powders.
  • a working space is defined by the value resulting from the formula:
  • the arithmetic product of the dead weight [kg] of each feeder unit and the refilling interval [h] is below 0.1 . Due to the low powder mass in the hopper a very sensitive scale can be used which leads to a very high accuracy. The low powder mass makes a more frequent refilling necessary. Other aspects of the accuracy of the feeder module are the subject of Applicant's co-pending application filed on the same day as the present application and the contents of which are incorporated by reference.
  • the storage hoppers of the respective feeder units are refilled intermittently as described in the above.
  • the method may include the further steps of detaching the storage hopper, the conveyer and the discharge end of each feeder unit from the weighing cell, and cleaning the storage hopper, the conveyer and the discharge end of each feeder unit in a contained manner.

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Filling Or Emptying Of Bunkers, Hoppers, And Tanks (AREA)

Abstract

L'invention concerne un module d'alimentation qui comprend un certain nombre d'unités d'alimentation, par exemple de cinq à huit. Chaque unité d'alimentation comprend une trémie de stockage, une cellule de pesée, un convoyeur et une extrémité de décharge. Les unités d'alimentation peuvent être agencées sur un seul niveau et dans une conception en rayons, dans laquelle chaque unité d'alimentation s'étend radialement vers l'extérieur depuis un cercle interne imaginaire défini au niveau de l'extrémité de décharge, capable de faire face au récipient de réception commun, jusqu'à un cercle externe imaginaire, défini par l'extrémité radialement opposée de chaque unité d'alimentation, les unités d'alimentation étant positionnées sensiblement sur les rayons s'étendant depuis le cercle interne. Le module d'alimentation permet de fournir un mélange dosé très précisément d'une ou de plusieurs poudres à un récipient de réception.
PCT/IB2012/052804 2012-06-04 2012-06-04 Module d'alimentation et procédé de fourniture d'un mélange d'une ou plusieurs poudres à un récipient de réception WO2013182870A1 (fr)

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PCT/IB2012/052804 WO2013182870A1 (fr) 2012-06-04 2012-06-04 Module d'alimentation et procédé de fourniture d'un mélange d'une ou plusieurs poudres à un récipient de réception

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Cited By (5)

* Cited by examiner, † Cited by third party
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JP2015528098A (ja) * 2012-06-04 2015-09-24 ヘーエーアー プロセス エンジニアリング ナームロゼ フェンノートシャップ フィーダ・ユニット、複数のフィーダ・ユニットを含むフィーダ・モジュール、及び１種又は２種以上の粉末の一定の質量流量を受容容器内へ放出する方法
CN108441591A (zh) * 2018-04-19 2018-08-24 中冶赛迪工程技术股份有限公司 一种混匀配料系统及方法
CN108905869A (zh) * 2018-08-17 2018-11-30 江苏康捷医疗器械有限公司 一种特殊的便捷型生物培养容器
EP3926308A1 (fr) * 2020-06-17 2021-12-22 Fette Compacting GmbH Procédé de fonctionnement d'un dispositif de mélange d'une installation
EP4144518A1 (fr) * 2021-09-06 2023-03-08 Kikusui Seisakusho Ltd. Système de mélange et d'alimentation en matériau pulvérulent

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EP0290999B1 (fr) 1987-05-12 1992-08-05 Fuji Photo Film Co., Ltd. "Fuzzy Inference" procédés de pesage de poudres et mélangeur mesureur
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