WO2013117332A1

WO2013117332A1 - Injection device

Info

Publication number: WO2013117332A1
Application number: PCT/EP2013/000359
Authority: WO
Inventors: Herbert Bechtold
Original assignee: Haselmeier Gmbh
Priority date: 2012-02-10
Filing date: 2013-02-06
Publication date: 2013-08-15
Also published as: DE202012001411U1; CN104220117A; CN105126203B; RU2615122C2; MX2014009123A; RU2014134275A; MX344115B; BR112014014902A2; CN105126203A; BR112014014902B1

Abstract

An injection device (1) has a housing (2) in which a seat is formed for a container (5) with injection liquid. The injection device (1) has a control knob (8) for setting an amount of injection liquid to be forced out of the container (5). The control knob (8) is rotatable for this purpose. During the rotation, the control knob (8) moves in the direction of a longitudinal centre axis (6) of the injection device (1) in a distal direction relative to the housing (2). To force injection liquid out of the container (5), the control knob (8) is moved in the direction of the longitudinal centre axis (6) in the proximal direction of the injection device (1). When setting the amount of injection liquid to be forced out, the control knob (8) can be adjusted to at least one injection position (100), in which an admissible amount of injection liquid is set, and to at least one blocking position (101), in which an inadmissible amount of injection liquid is set. In the injection position (100), the control knob (8) is movable in the direction of the longitudinal centre axis (6) in the proximal direction. To avoid the injection of an inadmissible amount of injection liquid, provision is made that, in the blocking position (101), the movement of the control knob (8) is blocked in the direction of the longitudinal centre axis (6) in the proximal direction.

Description

injection device

The invention relates to an injection device of the type specified in the preamble of claim 1.

From DE 10 2007 026 083 AI an injection device is known in which a knob is rotated to set the amount of liquid to be injected. By turning the control knob, the control knob moves with an injection sleeve in the distal direction of the injection device. The control knob has a locking device, which ensures that the control knob can only be placed in structurally predetermined positions. An adjustment of intermediate positions is not possible due to the sprung arms of the locking device. For expressing injection liquid, the control knob is moved in the proximal direction.

Thus, the control knob automatically and safely jumps from an intermediate position in a detent position, the detent must be sufficiently strong, and the radial detent positions must be sufficiently close to each other. However, the strength of the detent influences the torque that the user must use to turn the control knob and adjust the dose. The constructive possible distance of the locking positions is largely predetermined and can be adapted only within narrow limits to the application.

From EP 1 326 664 B1 an injection device for administering a medicament is known. The injection device has a rotary knob, which is rotated to adjust the amount of liquid to be injected. The control knob can only up to one maximum adjustable dose to be rotated. However, it is possible to adjust and inject less than the maximum dose.

The invention has for its object to provide an injection device of the generic type, in which only predetermined amounts of injection liquid can be pressed out of the container and allows a good adaptation to the desired application.

This object is achieved by an injection device having the features of claim 1.

In the intended injection device, it is permissible that the control knob in

Stations that correspond to impermissible levels of injection fluid. An interpretation of a locking device of the control knob, which ensures that the knob from a position between two locking positions automatically rotates in one of the two locking positions, so it is not required. Intermediate positions between permissible injection positions of the control knob also arise when the control knob between two allowable volume settings by a relatively large angle, for example by 90 ° or 180 °, must be rotated. If the positions of the control knob, which correspond to the permissible amounts of injection liquid are very far apart, it can be difficult to ensure that the locking device does not allow intermediate positions of the control knob.

In order to prevent the injection of an impermissible amount of injection liquid in an injection device whose control knob can be set in blocking positions, the inadmissible amounts of injection liquid to avoid, it is provided that the displacement of the control knob is locked in the proximal direction of the longitudinal central axis in the blocking positions. A locking device that ensures that the control knob stops only in injection positions and are not placed in blocking positions can, can be omitted. A locking device for the control knob can be adapted to the needs of the operator and be designed, for example, with very noticeable detents or with little noticeable detents, which also allow intermediate positions of the control knob. This achieves a high degree of operating comfort and at the same time it can be ensured that no impermissible quantities of injection liquid can be squeezed out of the container.

In this case, the "proximal direction" designates the injection direction, that is to say in the direction of a receptacle for the injection needle or the direction in which the injection liquid is pressed out of the container. The "distal direction" refers to the opposite direction, ie away from the injection needle. The distal end of the injection device is the end facing away from the injection needle. "Proximal" refers to the side of the injection device that faces the puncture site during an injection and "distal" to the side away from the puncture site.

Advantageously, the injection device has a first latching device which defines the at least one injection position. The locking device is designed so that even blocking positions, which are assigned to impermissible amounts of injection liquid, are adjustable. The first latching device advantageously has at least one latching element which cooperates with a latching contour. In injection position, the latching element is advantageously engaged in a latching recess of the latching contour. In the locked position, the latching element is deflected by the latching contour. It is intended that the

Injection device has a locking contour, which cooperates with the deflected locking element and locks in the blocking position of the control knob displacement of the control knob relative to the housing in the proximal direction. As a result, it can be ensured in a simple manner that the control knob can only be displaced in the proximal direction in constructively predetermined injection positions. Advantageously, the locking contour is formed on the control knob. This results in a compact design. The locking element is advantageously arranged within the control knob. The control knob is adjustable in particular with respect to the latching element between a first, distal position and a second proximal position. In the first position of the control knob, the locking element is arranged in a first axial portion of the control knob, which allows a deflection of the locking element. In the second position of the control knob, the latching element is advantageously arranged in a second axial section, which blocks a deflection of the latching element.

The locking element is advantageous relative to the longitudinal central axis deflected outwards, ie away from the longitudinal center axis. The control knob advantageously has in the first section a first inner diameter that is larger than a second inner diameter in the second section. As a result, a blocking contour can be realized in a simple manner. The control knob is advantageously sprung in the direction of its first, distal position.

The injection device advantageously has an injection sleeve which is non-rotatably and axially displaceably connected to the housing. The injection sleeve is connected via a first threaded connection with a metering member which is rotatably and axially immovably mounted relative to the housing. A rotation of the metering causes thus over the first threaded connection an axial displacement of the injection sleeve. The injection device advantageously has a first clutch, which produces a rotationally fixed connection between the control knob and the metering in the first position of the control knob. A rotation of the control knob thereby rotates the metering, whereby the injection sleeve is moved in the axial direction over the first threaded connection. Advantageously, the non-rotatable connection between the control knob and dosing is made via a driver which is rotatably connected to the metering and axially fixed and rotatably connected to the injection sleeve. The driver thereby moves together with the injection sleeve in the axial direction when the control knob is rotated.

In its second position, the control knob is advantageously rotatably connected via a second coupling with the injection sleeve. The latching element of the first latching device is advantageously a part of the second clutch, and the latching contour is formed on the injection sleeve. This results in a simple structure. When the control knob is in a locked position, the locking element blocks an axial displacement of the control knob and the second clutch can not be closed.

The injection device advantageously has a metering piston which is non-rotatably connected to the control knob and a second threaded connection with the metering. A rotation of the metering causes via the second threaded connection a movement of the metering piston, which serves for the extrusion of injection liquid. As long as the control knob is in the first, distal position and rotatably connected to the metering and the metering piston, no relative movement over the second threaded connection between metering and metering is possible, and it can be pressed out of the container no injection liquid. This ensures structurally that only in the second position of the control button injection liquid can be pressed. However, the second position of the control knob can only be adjusted when the control knob is in an injection position, ie in a position which is associated with a permissible amount of injection liquid.

A small size of the injection device can be achieved when the metering piston is rotatably connected to the control knob via a telescopic part, wherein the telescopic part against one of the parts of metering and control knob is axially displaceable. The telescopic part can be axially displaceable relative to the metering and be held on the control knob axially immovable or held against the metering axially non-displaceable and axially displaceable on the control knob. There- in that the telescopic part is displaceable axially relative to one of the parts of metering piston and control knob, ie in the direction of the longitudinal central axis of the injection device, the metering piston and control knob can be made shorter. This reduces the overall length of the injection device.

A simple structure results when the metering piston has a guide portion, and when the telescopic part has two guide webs which rest on opposite sides of guide surfaces of the guide portion. A compact construction results, although the control knob has two guide webs which protrude through at least one receptacle of the telescopic part, wherein the guide webs abut the guide portion of the metering piston in the circumferential direction between the guide webs of the telescopic part with the control knob fully depressed. The fact that the guide webs of telescopic part and control knob are adjacent to each other in the circumferential direction, resulting in a small outer diameter of the injection device.

It may be desirable that even when expressing injection liquid from the container to the user is noticeable or audible that a pressing of

Injection liquid takes place. For this purpose, a second locking device may be provided, which acts between metering and housing. The first latching device is only active when setting the amount of injection liquid to be pressed out, while the second latching device is active both when setting the quantity to be pressed out

Injection liquid as well as when expressing the injection liquid from the container is active. The second locking device can be designed very smoothly, so that the force to be applied by the operator during the injection process for squeezing the liquid is only slightly increased by the second locking device. Because both locking devices are active when setting the amount of injection liquid to be squeezed out, the locking positions can be made well palpable and / or audible to the operator. Embodiments of the invention are explained below with reference to the drawing. Show it:

1 is a side view of an injection device,

2 is a section along the line II-II in Fig. 1,

3 shows a side view of the injection device from FIG. 1 after setting the amount of injection liquid to be squeezed out, FIG.

4 shows a section along the line IV-IV in Fig. 3,

5 is a side view of the control knob of the injection device,

6 is a section along the line VI-VI in Fig. 5,

7 is a section along the line VII-VII in Fig. 5,

8 is a section along the line VIII-VIII in Fig. 6,

9 is a perspective view of a locking part of the injection device,

10 is a view of the locking part in the direction of the proximal end of

Injection device,

11 is a side view of the locking part,

12 is a section along the line XII-XII in Fig. 11, 13 is a side view of an injection sleeve of the injection device,

14 is a section along the line XIV-XTV in Fig. 13,

15 is a section along the line XV-XV in Fig. 13,

16 is a perspective view of a driver of the injection device,

17 is a side view of the driver of FIG. 16,

18 is a section along the line ΧνΐΠ-XVIII in Fig. 17,

19 is a section along the line ΧΓΧ-ΧΓΧ in Fig. 17,

20 is a section along the line XX-XX in Fig. 17,

21 is a side view of a metering of the injection device,

22 is a section along the line XXII-XXII in Fig. 21,

FIG. 23 shows a section along the line XXIII-XXIII in FIG. 21, FIG.

24 is a perspective view of a telescopic part of the injection device,

25 is a side view of the telescopic part,

26 is a side view in the direction of arrow XXVI in Fig. 25,

27 is a section along the line XXVÜ-XXVII in Fig. 25, 28 is a side view of a metering piston,

FIG. 29 shows a section along the line XXLX-XXLX in FIG. 28, FIG.

30 is a section along the line XXX-XXX in Fig. 28,

31 is a side view of a housing part of the injection device,

Fig. 32 is a side view of the housing part in the direction of arrow XXXII in

Fig. 31,

33 is a section along the line XXXIII-XXXIII in Fig. 32,

FIG. 34 shows a section along the line XXXTV-XXXIV in FIG. 32, FIG.

35 is an enlarged view of the detail XXXV of FIG. 33,

FIG. 36 shows a section along the line XXXVI-XXXVI in FIG. 33, FIG.

37 is an enlarged view of the section XXXVII of FIG. 33,

Fig. 38 is a section along the line XXXVIII-XXXVIII in Fig. 1 in

Injection position of the control knob,

39 is a section along the line XXXVIII-XXXVIII in Fig. 1 in the locked position of the control knob, 40 is a side view of the injection device after adjusting the amount of injection liquid to be squeezed and after pressing the control knob in its second, proximal position,

41 shows a section along the line XLI-XLI in Fig. 40,

Fig. 42 is a section along the line XXXVIII-XXXVIII in Fig. 1 at a

Embodiment of the injection device,

Fig. 43 is a section along the line XXXVIII-XXXVIII by another

Embodiment of the injection device with the control knob in Inj ektionsstellung.

Fig. 1 shows an injection device 1, which has a housing 2. The housing 2 comprises a distal housing part 3 and a holder 4 fixed to the proximal side of the distal housing part. The holder 4 may be firmly fixed to the distal housing part 3, for example by welding to it. However, the holder 4 can also be removably held on the housing part 3, for example, screwed to the housing part to allow replacement of the container 4 arranged in the holder 4, shown in Fig. 2. The container 5 contains injection liquid. The holder 4 forms a receptacle for the container 5. At its proximal end, the holder 4 has a connecting element to which an injection needle can be attached. In the exemplary embodiment, the connecting element is a standardized external thread 11, onto which an injection needle with a corresponding internal thread can be screwed. Instead of the external thread 11, another connection element may also be provided at the proximal end of the holder 4. The connecting element is adapted to the intended type of injection needle. On the housing 2, a dashed line indicated in Fig. 1, only partially shown cap 10 can be placed, which surrounds the holder 4. The injection device 1 has a longitudinal central axis 6. At the distal end of the injection device 1, a control knob 8 is arranged.

As shown in Fig. 1, the distal housing part 3 has a viewing window 7, which is made for example of transparent plastic. The viewing window 7 can be produced as a separate component or can be produced in one piece in a two-component injection molding process with the distal housing part 3. It can also be provided that the

Housing part 3 with the viewing window 7 is completely made of a transparent plastic, which can be roughened except in the region of the viewing window 7, painted or otherwise masked, so that only the area of the viewing window 7 is transparent.

Fig. 2 shows the structure of the injection device 1 in detail. Inside the container 5, a plug 21 is arranged, against which a metering piston 103 of the injection device. The metering piston 103 has a piston disk 20, which bears against the plug 21, and a piston rod 19 rotatably connected to the piston disk 20. The piston rod 19 is non-rotatably connected via a telescopic part 18 to a guide 17 of the control knob 8. The control knob 8 is shown in Fig. 2 in its first, distal position 95. Inside the control knob 8, a compression spring 13 is arranged, which loads the control knob 8 in the direction of its first position 95. The compression spring 13 is supported with a first end on an end face 105 of the control knob 8 and with a second end on a driver 16. The driver 16 is rotatably in the first position 95 of the control knob 8 shown in Fig. 2 via a first clutch 23 connected to the control knob 8. The driver 16 is arranged on the outer circumference of the guide 17 of the control knob 8. On the outer circumference of the driver 16, a sleeve-shaped metering member 15, which is also referred to as a scale tube and rotatably and axially slidably connected to the driver 16 extends.

The metering member 15 is surrounded by an injection sleeve 14 which projects as well as the driver 16 with its distal end in the control knob 8. The metering 15 is connected to the injection sleeve 14 via a first threaded connection 33. The metering member 15 is rotatably and axially non-displaceably held on the housing part 3 at its proximal end on a bearing 32. The injection sleeve 14 is in the housing part 3 axially, so slidably held in the direction of the longitudinal central axis 6 but rotatably. In the control knob 8, a locking member 12 is arranged, which is rotatably mounted in the control knob 8 and which cooperates with the injection sleeve 14 and forms with this a first latching device 29. A second latching device 30 acts between the housing part 3 and the outer periphery of the metering member 15 adjacent to the proximal end of the metering member 15. The latching devices 29 and 30 do not extend in the sectional plane shown in Fig. 2, so that the associated reference numerals indicate only where the Catches 29 and 30 are arranged without showing their construction in detail. The locking part 12 is part of a second clutch 24 which is open in the first position 95 of the control knob 8. The second clutch 24 rotatably connects the control knob 8 in its second position 96 (FIG. 40) with the injection sleeve 14.

FIG. 2 shows the injection device 1 after the injection of injection liquid and before the setting of the quantity of injection liquid to be expelled from the container 5 during the next injection. This position of the injection sleeve 14 is defined by a first stop 26 which is formed between the injection sleeve 14 and the housing part 3. For adjusting the amount of injection liquid to be injected, the operation knob 8 is rotated. The control knob 8 is rotatably connected in its first position 95 with the driver 16 and the metering member 15 and with the metering piston 103. When the control knob 8 is rotated, the driver 16 and the metering member 15 rotate with. The first threaded connection 33 causes a relative axial movement between injection sleeve 14 and metering member 15. The injection sleeve 14 is thereby displaced in the distal direction, ie in the direction of the arrow 25, when the control knob 8 is rotated in the direction corresponding to an increase in the set dose , Due to the bearing 32 of the metering member 15 in the housing part 3, which prevents axial movement of the metering member 15, the injection sleeve 14 pushes axially from the housing part 3 and takes the driver 16 and the control knob 8 with. When adjusting the amount of injection liquid to be squeezed, both the first latching device 29 and the second latching device 30 are active, since both the control knob 8 rotates with respect to the injection sleeve 14 and the metering member 15 with respect to the housing part 3.

FIGS. 3 and 4 show the injection device 1 after the amount of injection liquid to be squeezed out has been set. The maximum amount of injection liquid to be squeezed is set here. This position is defined by a second stop 27, which is also between the injection sleeve 14 and the

Housing part 3 is formed.

For expressing the set amount of injection liquid, the control knob 8 is pressed in the direction of arrow 28 in Fig. 4. Thereby, the first clutch 23 is opened and the second clutch 24 is closed. This will be described in more detail below. The compression spring 13 is designed so that initially the control knob 8 relative to the injection sleeve 14 moves in the proximal direction, before the injection sleeve 14 is displaced in the axial direction. When the second clutch 24 is closed, the control knob 8 is non-rotatably connected to the injection sleeve 14. By the movement of the injection sleeve 14 in the direction of the arrow 28 in the proximal direction, the metering member 15 is rotated. Between the metering member 15 and the piston rod 19, a second threaded connection 34 is formed. Since the piston rod 19 is rotatably connected via the telescopic part 18 with the control knob 8, the piston rod 19 can not rotate relative to the injection sleeve 14. The rotation of the metering member 15 relative to the injection sleeve 14 thereby causes a movement of the piston rod 19 in the proximal direction, which moves the plug 21 in the container 5 and leads to the ejection of injection liquid from the container 5. Since the metering member 15 rotates relative to the housing part 3, the second latching device 30 is also active when expressing injection liquid and also shows the operator acoustically, the squeezing of injection liquid. Since the first clutch 23 is released, the driver 16 can rotate relative to the control knob 8 together with the metering member 15.

In the following, the components of the injection device 1 are explained in detail. The components represent functional groups, which are drawn in one piece for the sake of simplicity. In order to simplify the manufacture of the parts, however, it may be advantageous to manufacture the elements from several individual parts.

Figures 5 to 8 show the structure of the control knob 8 in detail. As FIGS. 5 to 7 show, the guide 17 of the control knob 8 is formed by two guide webs 36, which are aligned in the direction of the longitudinal central axis 6 of the injection device 1. At the mutually facing longitudinal sides of the guide webs guide surfaces 37 are formed.

The control knob 8 has a first portion 38 in which the control knob 8 has an inner diameter a. A second section 39, whose inner diameter b is smaller than the inner diameter a in the first section 38, adjoins the first section 38 in the distal direction. Between the two sections 38 and 39, a step is formed which forms a blocking contour 102 which will be described in more detail below. In the distal direction, the first portion 38 is bounded by holding portions 43 which project radially inward, as shown in FIG. 8. The holding portions 43 engage on the edge 49 of the injection sleeve 14 shown in FIG. 13 and fix the injection sleeve 14 in the direction of the longitudinal central axis 6 on the control knob 8.

The control knob 8 has in its interior a protruding from the end face 105 in the proximal direction stub 40, at the end of an outer toothing 41 is arranged. As shown in FIG. 8, the outer teeth 41 are made of individual outwardly projecting teeth arranged side by side in groups of three teeth each are, wherein between the individual groups of teeth in each case a distance is formed. However, the external teeth 41 may also extend over the entire outer circumference of the nozzle 40. The external toothing 41 is arranged in the first section 38. As also shown in FIG. 8, the control knob 8 has longitudinally extending guide grooves 42 which extend over the first section 38 and the second section 39. In the exemplary embodiment, two oppositely arranged guide grooves 42 are provided. The guide grooves 42 serve to receive guide webs 44 of the locking part 12, which are shown in Fig. 9. The locking part 12 has a ring 107. On its opposite sides two radially outwardly projecting guide webs 44 are arranged. The guide webs 44 each carry two latching arms 45, which extend in the circumferential direction in both directions of the guide webs 44 and which are arranged at the proximal side of the ring 107 at a small distance from the ring 107. At the free ends of the latching arms 45 inwardly projecting detents 46 are formed. This also show the figures 7 to 12. The locking arms 45 with the detents 46 form locking elements. As shown in FIG. 10, the latching arms 45 and the detents 46, viewed in the direction of the longitudinal center axis 6, overlap with the ring 107, ie they do not project beyond the ring 107. The detents 46 cooperate with a detent contour 47 formed on the injection sleeve 14, which is shown in FIG. 13. The locking contour 47 is bounded at its distal end by a first edge 48 and at its proximal end by the second edge 49, which engages behind the holding portions 43. The first, distal edge 48 protrudes between the ring 107 of the latching part 12 and the latching arms 45, as shown in FIGS. 2 and 4, and thereby fixes the latching part 12 in the direction of the longitudinal central axis 6 on the injection sleeve 14.

As shown in FIG. 13, the injection sleeve 14 has a shoulder 97, on which the outer diameter of the injection sleeve 14 increases in the proximal direction. As shown in FIG. 2, a distance c is formed between the proximal end of the control knob 8 and the shoulder 97. When pressing the control knob 8 in the proximal direction of the paragraph 97 forms a stop for the control knob 8. The injection sleeve 14 has a Window 31, in the middle of a marker arrow 54 protrudes indicating the set dose. The injection sleeve 14 has a cover 56 arranged proximally to the window 31. The cover 56 serves to cover the metering element, so that only the marking of the metering element 15 arranged in the window 31 is visible through the viewing window 7. The cover 56 extends in the position of the injection device 1 shown in Figures 1 and 2 into the region of the holder 4. As shown in FIG. 1, a tongue 9 is arranged on the distal housing part 3, which protrudes over the holder 4 and the the cover 56 covers.

As shown in Fig. 14, the injection sleeve 14 has approximately at the height of the shoulder 97 inwardly projecting locking projections 53. In the embodiment, four evenly distributed over the circumference locking projections 53 are provided. The latching projections 53 latch on the driver 16, specifically on the groove 59 of the driver 16 shown in FIGS. 16 and 17, and form a bearing 35, shown in FIG. 4, for the driver 16. Via the latching projections 53 protruding into the groove 59 the driver 16 on the injection sleeve 14 axially immovable but rotatably mounted.

As also shown in FIG. 14, the injection sleeve 14 has an internal thread 55, which is formed adjacent to the proximal end of the injection sleeve 14. In the region of the latching projections 53, the internal thread 55 is interrupted, so that the injection sleeve 14 can be produced in an injection molding process. The internal thread 55 forms the first threaded connection 33 with the external thread 62 of the metering element 15 shown in FIGS. 21 and 22.

As FIGS. 14 and 15 show, the injection sleeve 14 has a longitudinal groove 50 on its side facing away from the window 31. The longitudinal groove 50 is formed in the region of a thickening 89 of the injection sleeve 14. In the longitudinal groove 50 protrudes a projection 90 of the housing part 3 (Fig. 33 and 37). The projection 90 has a proximal edge 91, which with the proximal end 52 of the longitudinal groove 50 that shown in Fig. 4 second stop 27 forms. The projection 90 also has a distal edge 92 which forms the first stop 26 (Fig. 2) with the distal end 51 of the longitudinal groove 50. As shown in FIG. 36, the projection 90 is disposed in a longitudinal groove 88. The longitudinal groove 88 is formed so that the thickening 89 of the injection sleeve 14 is in place. The fact that the groove 50 and the projection 90 are arranged in the radial direction centrally between the injection sleeve 14 and the housing part 3 with respect to the longitudinal center axis 6, results in a small outer diameter of the overall arrangement.

Figures 16 to 20 show the driver 16 in detail. The driver 16 has at its distal end an internal toothing 57 which cooperates with the external teeth 41 on the neck 40 of the control knob 8 (FIG. 8). Adjacent to the internal teeth 57 recesses 58 are arranged on the proximal side of the internal teeth 57. If the control knob 8 is displaced in the proximal direction with respect to the driver 16, then the external teeth 41 of the control knob 8 from the region of the internal teeth 57 of the driver 16 in the region of the recesses 58, whereby the rotationally fixed connection between the control knob 8 and driver 16 is released. The configurations of the internal teeth 57 and the recesses 58 are also shown in detail in FIGS. 18 and 19.

The driver 16 has an edge 106 which limits the groove 59 on the proximal side. The edge 106 limits the insertion depth of the driver 16 in the metering member 15, as shown in FIG. 2. At its adjoining the edge 106 portion of the driver 16 is sleeve-shaped and has on its outer circumference four evenly distributed on the outer circumference longitudinal grooves 60, which, as Fig. 20 shows, have a trapezoidal cross-section. As shown in FIGS. 22 and 23, the metering element 15 has corresponding, radially inwardly projecting longitudinal webs 68. The longitudinal webs 68 protrude into the longitudinal grooves 60 and thereby connect the driver 16 in a rotationally fixed manner to the metering device 15. Figures 21 to 23 show the design of the metering member 15 in detail. The metering member 15 is formed sleeve-shaped and has on its outer circumference the external thread 62, which cooperates with the internal thread 55 of the injection sleeve 14. On the metering member 15, a scale 61 is printed, the values of which increase from the proximal end of the metering member 15 to the distal end. The scale 61 is shown schematically in Fig. 21, with only even numbers shown. The odd numbers can advantageously be indicated by dashes between the numbers. These bars are not shown in the illustration in FIG. 21. In the embodiment 20 setting positions per revolution of the metering 15 are provided. The larger the dose set via the control knob 8, the further the injection sleeve 14 has shifted in the distal direction relative to the metering member 15. In this displacement, the window 31 of the injection sleeve 14 moves so that the displayed number of the scale 61, which corresponds to the set amount of injection liquid, increases. The cover 56 covers the values of the scale 61 which are not arranged within the window 31, so that it is avoided that a plurality of values of the scale 61 are displayed in the viewing window 7 of the housing 2.

At its proximal end, the metering member 15 has a latching contour 63, which is part of the second latching device 30 (FIG. 2). The metering member 15 has at its proximal end also four radially outwardly projecting latching hooks 64, which are part of the bearing 32 and engage behind a latching edge 85 of the housing part 3 shown in Fig. 35. As a result, the metering member 15 is secured in the axial direction on the housing part 3. At its proximal end, the metering member 15 also has an inner, cylindrical neck 65, which has an internal thread 66. The internal thread

66 interacts with an external thread 76 of the metering piston 103 shown in FIG. 28 and forms with it the second threaded connection 34. As FIG. 22 also shows, the metering device 15 has inwardly protruding latching hooks 67 which are used for the axial fixation of the coupling shown in FIG shown telescopic part 18 serve. To do this, the locking hooks snap

67 in a groove 69 shown in Fig. 24 of the telescopic part 18 a. The telescopic part 18 is shown in detail in FIGS. 24 to 27. The telescope part 18 has a proximal pin 70, which has a square opening 71. At its distal end, the telescopic part 18 has a ring 72. Between the pin 70 and the ring 72 extend two guide webs 73, whose mutually facing surfaces are formed as guide surfaces 74. At the radially outwardly facing side of the guide webs 73, a respective extending in the longitudinal direction stiffening web 75 is attached. As shown in FIG. 27, the guide webs 73 are chamfered at their outer edges. In the ring 72, a receptacle 104 is formed.

FIGS. 28 to 30 show the design of the metering piston 103 in detail. The metering piston 103 has at its distal end of the piston disc 20, a guide portion 77. As shown in FIG. 30, the guide portion 77 has a rectangular, in particular square cross-section. At the guide portion 77, two opposing first guide surfaces 78 are formed, on which the guide surfaces 37 of the guide webs 36 of the control knob 8 can rest. The two other opposing guide surfaces 79 abut against the guide surfaces 74 of the telescopic part 18. The receptacle 104 in the telescope part 18 is designed so that the guide portion 77 and arranged on the guide surfaces 78 guide webs 37 of the control knob 8 can be inserted therethrough. In the arrangement of the injection device 1 shown in FIG. 2 after an injection, the injection sleeve 14 is arranged in its proximal position. In this position, the guide 17 of the control knob 8 projects through the receptacle 104. If the maximum dose is set, as shown in FIG. 4, the guide 17 has a distance to the piston rod 19. This distance is bridged by the telescopic part 18, which is rotatably connected both with the guide portion 77 and with the guide 17. Thereby, the guide 17 on the control knob 8 are formed comparatively short, so that a small length of the injection device 1 in the state shown in Figures 1 and 2, ie after a successful injection results. Figures 31 to 37 show the design of the housing part 3 in detail. As shown in FIGS. 33 and 37, the housing part 3 has a wall 83 which is perpendicular to the longitudinal central axis 6 and which has an opening 87. The opening 87 is bounded by an inner sleeve 86, which is integrally formed on the wall 83 and projecting in the distal direction. Radially outside the inner sleeve 86, a sleeve portion 84 is arranged, which carries a locking rim 85 protruding in the distal direction, to which the latching hooks 64 of the metering member 15 hook.

Adjacent to the wall 83, on the distal side of the wall 83, two locking arms 80 are integrally formed on the housing part 3, which are shown in Fig. 34. The latching arms 80 are held by a holding web 82 on the housing part 3 and carry at their free ends detents 81. The detents 81 are arranged approximately opposite each other in the embodiment and engage in the detent contour 63 on the metering 15 a. The detents 81 form with the detent contour 63 the second detent device 30.

FIG. 38 and FIG. 39 show sections through the control knob 8. In FIG. 38, the control knob 8 is shown in the injection position 100 and in the blocking position 101 in FIG. 39. In the injection position 100, an admissible dose of injection liquid is set, whereas the injection fluid shown in FIG 39 set amount of injection fluid is not allowed. The allowable amount of injection liquid is a constructively predetermined amount that corresponds to a desired dose of the drug to be administered with the injection device. Several quantities may be permissible, for example multiple doses of a single dose. Impermissible quantities of injection fluid are amounts that should not be administered, for example, because the effectiveness of the drug is demonstrated only for permissible levels of injection fluid or because self-adjustment of the dose by the patient and administration of an unspecified amount of drug is avoided should. As FIG. 38 shows, the detent contour 47 on the injection sleeve 14 has elevations 93 and detent recesses 94. The detents 46 of the detent part 12 are each arranged in a detent recess 94. As a result, the detents 46 are pivoted radially inward. Fig. 38 also shows the arrangement of the external teeth 41 of the control knob 8 in the internal teeth 57 of the driver 16. External teeth 41 and internal teeth 57 are shown in FIG. 38 the same height, but arranged below the cutting plane. About the external teeth 41 and the internal teeth 57, a rotationally fixed connection between the driver 16 and the control knob 8 is made.

From the injection position 100 shown in FIG. 38, the control knob 8 can be pressed in the direction of the arrow 28 shown in FIG. 4 in the proximal direction into the second proximal position 96 shown in FIGS. 40 and 41. As a result, the latching part 12 with the detents 46 reaches the second section 39 shown in FIGS. 6 and 41, which has a smaller diameter b than the section 38 shown in FIG. 38. The outer diameter of the latching part 12 in the region of the latching arms 45 is sufficiently small when arranged in the locking recesses 94 notches 46 so that the control knob 8 can be moved in the proximal direction and an injection can be triggered. In the second position 96 of the control knob 8, the latching arms can no longer be deflected radially outwards, since the cylindrical outer wall of the first section 38 prevents this movement. As a result, the control knob 8 is rotatably connected via the locking part 12 with the injection sleeve. The second clutch 24, which is formed by the locking part 12, is closed. When pressing the control knob in its second position 96, the outer teeth 41 moves on the control knob 8 in the proximal direction and passes from the region of the internal teeth 57 in the region of the recesses 38. Thus, the first clutch 2 is opened and the driver is opposite to

Control knob 8 rotatable. Fig. 39 shows the control knob 8 in blocking position 101. In this position, the detents 46 are in the region of the elevations 93 of the locking contour 47. As a result, the latching arms 45 are deflected radially outwards. The inner diameter in the second portion 39 is shown in Fig. 39 in dashed line. As the figure shows, the dashed line intersects the latching arms 45. As a result, a movement of the control knob 8 in the proximal direction is not possible. The blocking contour 102 shown in FIG. 6 bears against the latching arms 45 and thus prevents a displacement of the control knob 8 in the proximal direction. As a result, the triggering of an injection or the pressing out of injection liquid from the container 5 in a blocking position 101 of the control knob 8 is not possible.

As the figures show, the locking arms 45 are designed very narrow. The force exerted by the latching arms 45 in the radial direction inwardly is therefore very small. The force exerted by the latching arms 45 on the latching contour 47 is too low to turn the control knob 8 into an injection position 100. As a result, in the injection device 1 shown a blocking position 101 of the control knob can be adjusted. The blocking contour 102 prevents injection liquid from being pressed out of the container 5 in a blocking position 101 of the operating button 8.

Figures 42 and 43 show sections corresponding to Fig. 38 by embodiments. In Fig. 42, a locking contour 98 is provided on the injection sleeve 14, the locking recesses 94 has, between which elevations 108 are formed. The elevations 108 extend in the exemplary embodiment in each case over a circumferential angle of about 18 °. At the elevations 108, the outer diameter of the

Injection sleeve 14 constant. In the region of the elevations 108, the latching arms 45 can not spring inwards. Of the locking arms 45, no force can be exerted in the circumferential direction on the locking contour 98 in this area. In the design of the latching contour 98 shown in FIG. 42, even with a very strong design of the latching arms 45, a position of the control knob 8 is in a plurality of blocking positions 101 possible. In the exemplary embodiment shown in FIG. 42, a total of ten detent positions are possible, while in the exemplary embodiment according to FIGS. 38 to 41 a total of 20 positions are provided on the outer circumference.

In the embodiment shown in Fig. 43, a locking contour 99 is shown in which only two injection positions are provided. In each case, an angle of 180 °, ie half a turn of the control knob 8, is located between the injection positions. In order to reach detent positions between the injection positions, six detent recesses 94 are arranged next to each other, between which elevations 110 extend. The ridges 110 extend over different circumferential angles. However, it can also be provided that the elevations 110 extend over the same circumferential angle. The arrangement of the elevations 110 and the latching recesses 94 is selected so that only in two positions of the control knob 8, namely in the position shown and rotated by 180 °, all the detents 46 are arranged in latching recesses 94. In all other positions, at least one detent 46 is deflected radially outward by an elevation 110, so that a displacement of the operating button 8 in the proximal direction into the second position 96 shown in FIG. 40 is not possible. The detent recesses 94 are also arranged so that at each rotation of the control knob 8 by 18 ° at least one detent 46 engages in a detent recess 94, so that there are 20 noticeable detent positions. In the injection position 100 shown in FIG. 43, the control knob 8 can be displaced in the axial direction with respect to the driver 16 and the injection sleeve 14, from the first, distal position 95 shown in FIG. 1 to that shown in FIG , Second, proximal position 96. In the proximal position 96, the holding portion 43 abuts the shoulder 97 of the injection sleeve 14.

The arrangement of the locking recesses and elevations can be arbitrarily adapted to the particular application. It can also be provided that between the injection positions 100 no locking positions are given and the only noticeable Latching results due to the second locking device 30 between metering member 15 and housing part 3.

Claims

Expectations

Injection device with a housing (2) in which there is a receptacle for a container

(5) is designed with injection fluid, with a control button (8) which can be rotated to adjust the amount of injection fluid to be squeezed out of the container (5) and which moves distally when rotating in the direction of a longitudinal central axis (6) of the injection device (1). Direction of the injection device (1) relative to the housing

(2) moves, the control button (8) for squeezing injection fluid from the container (5) in the direction of the longitudinal central axis

(6) is moved in the proximal direction of the injection device (1),

characterized in that the control button (8) when setting the amount of injection fluid to be squeezed out in at least one injection position (100), in which a permissible amount of injection fluid is set, and in at least one blocking position (101), in which an impermissible amount of injection fluid is set, is adjustable, wherein the control button (8) in the injection position (100) is displaceable in the proximal direction in the direction of the longitudinal central axis (6), and wherein in the locked position (101) of the control button (8), the displacement of the control button (8) in Direction of the longitudinal central axis (6) is blocked in the proximal direction.

Injection device according to claim 1,

characterized in that the injection device (1) has a first locking device (29) which defines the at least one injection position (100).

3. Injection device according to claim 2,

characterized in that the first locking device (29) has at least one locking element which cooperates with a locking contour (47), the locking element being locked in a locking recess (94) of the locking contour (47) in the injection position (100) and in the locking position (101 ) is deflected by the locking contour (47), the injection device (1) having a locking contour (102) which interacts with the deflected locking element and in the locking position (101) of the control button (8) a displacement of the control button (8) relative to the housing (2) blocks in the proximal direction.

4. Injection device according to claim 3,

characterized in that the locking contour (102) is formed on the control button (8).

5. Injection device according to claim 3 or 4,

characterized in that the control button (8) is adjustable relative to the locking element between a first, distal position (95) and a second, proximal position (96), the locking element being in the first position (95) of the control button (8) in one first axial section (38) of the control button (8) is arranged, which allows deflection of the locking element, and wherein the locking element is arranged in the second position (96) in a second axial section (39), which blocks deflection of the locking element.

6. Injection device according to claim 5,

characterized in that the locking element can be deflected outwards with respect to the longitudinal central axis (6), and in that the control button (8) in the first section (38) has a first inner diameter (a) which is larger than a second inner diameter (b). the second section (39).

7. Injection device according to claim 5 or 6,

characterized in that the control button (8) is spring-loaded towards its first, distal position.

8. Injection device according to one of claims 5 to 7,

characterized in that the injection device (1) has an injection sleeve (14) which is connected to the housing (2) in a rotationally fixed and axially displaceable manner, the injection sleeve (14) being connected to a metering element (15) via a first threaded connection (33). is connected, and wherein the metering element (15) is rotatably and axially immovably mounted relative to the housing (2).

9. Injection device according to claim 8,

characterized in that the injection device has a first coupling (23) which, in the first position (95) of the control button (8), establishes a non-rotatable connection between the control button (8) and the dosing element (15).

10. Injection device according to claim 9,

characterized in that the non-rotatable connection between the control button (8) and the dosing element (15) takes place via a driver (16) which is non-rotatably connected to the dosing element (15) and which is axially fixed and rotatably connected to the injection sleeve (14).

11. Injection device according to one of claims 8 to 10,

characterized in that the control button (8) is non-rotatably connected to the injection sleeve (14) in its second position (96) via a second coupling (24).

12. Injection device according to speech 11,

characterized in that the latching element of the first latching device (29) is part of the second coupling (24), and that the latching contour (47) of the first latching device (29) is formed on the injection sleeve (14).

13. Injection device according to one of claims 8 to 12,

characterized in that the injection device (1) has a metering piston (103) which is non-rotatably connected to the control button (8) and which is connected to the metering element (15) via a second threaded connection (34).

14. Injection device according to claim 13,

characterized in that the metering piston (103) is connected in a rotationally fixed manner to the control button (8) via a telescopic part (18), the telescopic part (18) being axially displaceable relative to one of the parts of the metering piston (103) and the control button (8).

15. Injection device according to claim 14,

characterized in that the metering piston (103) has a guide section (77), the telescopic part (18) having two guide webs (73) which rest on guide surfaces (78) of the guide section (77) on opposite sides.

16. Injection device according to claim 15,

characterized in that the control button (8) has two guide webs (36) which protrude through at least one receptacle (104) of the telescopic part (18), the guide webs (36) of the control button (8) being fully pressed in Circumferential direction between the guide webs (73) of the telescopic part (18) rest on the guide section (77) of the metering piston (103).

17. Injection device according to one of claims 8 to 16,

characterized in that a second locking device (30) acts between the metering element (15) and the housing (2).

18. Injection device according to claim 17,

characterized in that the second locking device (30) has at least one locking arm (80) arranged on the housing (2), which interacts with a locking contour (63) on the outer circumference of the metering element (15).