WO2012145882A1 - Ophthalmic optical coherence tomography (oct) system and ophthalmic oct imaging method - Google Patents

Abstract

An ophthalmic optical coherence tomography (OCT) system includes an OCT imaging system for a posterior segment of an eye and an OCT imaging system for an anterior segment of an eye. The OCT imaging system for the posterior segment of the eye includes a light path conversion device, and the OCT imaging system for the anterior segment of the eye includes a probe imaging device for the anterior segment of the eye. The probe imaging device for the anterior segment of the eye includes an ophthalmoscope, a first dichroscope and a first lens. When the ophthalmic OCT system is scanning image for the anterior segment of the eye, and after the light path conversion instruction is received by the light path conversion device, the signal light sent from the light source through the collimating mirror and scanning device respectively is converted into the probe imaging device for the anterior segment of the eye; the probe imaging device for the anterior segment of the eye drives the first dichroscope to cause the signal light to be reflected into the ophthalmoscope so as to carry out the scan imaging for the anterior segment of the eye. An ophthalmic OCT imaging method is used to image the anterior segment of the eye, which can both remain the point of fixation clear during dioptric compensation and not influence the OCT imaging quality for the anterior segment of the eye.

Description

 Ophthalmology OCT system and ophthalmology OCT imaging method

 The present invention relates to the field of optoelectronics, and more particularly to an ophthalmic OCT system and an ophthalmic OCT imaging method. Background technique

 Optical Coherence Tomography (OCT) is an emerging optical imaging technology with high resolution, imaging speed, no radiation damage, moderate price, and compact structure compared with traditional clinical imaging methods. , an important potential tool for basic medical research and clinical diagnostic applications. Currently, in a variety of ophthalmic devices using optical instruments, OCT devices for ophthalmic examination and treatment have become indispensable ophthalmic devices for the diagnosis of ophthalmic diseases.

 The patent document US 2009/0168017 A1 discloses an OCT device for realizing anterior segment imaging in an OCT system of the eye, as shown in FIG. 1 , a lens 132 is inserted after the sample arm scanning galvanometer 130 to realize anterior segment imaging, due to the measurement. The diopter of the subject is different, such as myopia and hyperopia. In order to ensure that the gaze point can be clearly imaged on the retina of the human eye, a refractive adjustment device is needed, so that the gaze path of the system and the anterior segment imaging optical path share the diopter adjustment device; The anterior segment OCT imaging light path does not require refractive adjustment, and in order to ensure that the fixation point in the gaze path can be clearly imaged at the fundus, refraction adjustment is required, and the system uses the anterior-posterior movement of the ophthalmoscope to achieve diopter adjustment, however, the anterior segment The OCT imaging optical path and the gaze optical path share the ophthalmoscope. When the ophthalmoscope moves, it can make the fixation point clear in the fundus, but it will affect the OCT imaging quality of the anterior segment. It is difficult to achieve the simultaneous gaze adjustment and OCT imaging quality. Optimal state, there is a good match between gaze point adjustment and OCT imaging quality. Problem. Moreover, the movement of the ophthalmoscope makes it difficult to ensure that the scanning light must be perpendicular to the cornea (the scanning beam is perpendicular to the cornea from the literature), which will cause great difficulty in image correction and affect the imaging quality of the OCT.

The patent document US 2008/0106696 A1 discloses another OCT system for implementing the anterior segment imaging function in the posterior segment of the eye, as shown in FIG. 2, by adding an anterior segment mirror 770 behind the fundus mirrors 750, 760. In the imaging of the anterior segment of the eye, the scanning mode of the vertical cornea is adopted. This method also faces the problem that the fixation of the fixation point and the quality of the OCT imaging cannot be well matched, and the method has high requirements for the design of the lens and is difficult to implement. Because, in real life, different human eyes have different diopter, such as myopia and hyperopia, when the eye is tested, it is often necessary to adjust the diopter. How to realize the anterior segment imaging function for the human eye with different vision in the posterior segment OCT system At the same time, it is a hot issue that people have been studying to be able to perform refractive compensation and keep the fixation point clear without affecting the imaging quality of the OHT in the anterior segment of the eye. Summary of the invention

 The technical problem to be solved by the embodiments of the present invention is to provide an ophthalmic OCT system and an ophthalmic OCT imaging method, which can solve the problem that the gaze point adjustment and the OCT imaging quality cannot be well matched in the prior art, and the system structure is simple. Easy to operate.

 In order to solve the above technical problem, an embodiment of the present invention provides an ophthalmologic OCT system, including an ophthalmologic OCT imaging system and an anterior segment OCT imaging system, the posterior segment OCT imaging system including an optical path conversion device, the anterior segment OCT The imaging system includes an anterior segment probe imaging device, the anterior segment probe imaging device including an ophthalmoscope, a first dichroic mirror, and a first lens, wherein

 When the ophthalmic OCT system performs the anterior segment scan imaging, the optical path conversion device converts the signal light emitted from the light source and passed through the collimating mirror and the scanning device to the anterior segment probe imaging after receiving the optical path switching instruction. In the device;

 The anterior segment probe imaging device drives the first dichroic mirror to reflect the signal light into the ophthalmoscope for anterior segment scan imaging.

 Wherein the ophthalmic OCT system further comprises a fixation optical system and an iris imaging optical system, wherein the fixation optical system comprises a fixation light source, a refractive adjustment device, a second lens, and the ophthalmoscope;

 The iris imaging optical system includes an imaging light source, an imaging device, a third lens, and the ophthalmoscope.

 The initial state of the ophthalmologic OCT system is to perform imaging of the posterior segment of the eye. After the ophthalmic OCT system completes the imaging of the anterior segment of the eye, the initial state of the posterior segment scan imaging is adjusted, and the first dichroic mirror is Evacuate the light path.

 Wherein the posterior segment OCT imaging system further includes a second dichroic mirror, the second dichroic mirror being located between the refractive adjustment device and the transmission optical path of the second lens;

When the ophthalmic OCT system performs imaging of the posterior segment of the eye, the optical path conversion device converts signal light emitted from the light source and passed through the collimating mirror and the scanning device to the second dichroic mirror, a second dichroic mirror reflects the signal light and sequentially enters the refractive adjustment device and the ophthalmoscope to perform imaging of the posterior segment of the eye; or

 The optical path conversion device directly converts the signal light emitted from the light source and respectively passed through the collimating mirror and the scanning device to the refractive adjustment device and the ophthalmoscope to perform imaging of the posterior segment of the eye.

 The light source signal of the fixation source passes through the second lens and is directly transmitted by the second dichroic mirror and sequentially enters the refractive adjustment device and the ophthalmoscope.

 Wherein, the optical path conversion device is a rotation-adjustable total reflection mirror;

 When the ophthalmic OCT system performs the anterior segment scan imaging, the optical path conversion device rotates the preset angle according to the design of the optical path after receiving the optical path conversion command, and the signal emitted from the light source and passed through the collimating mirror and the scanning device respectively Converting light into the anterior segment probe imaging device; the anterior segment probe imaging device driving the first dichroic mirror to insert an optical path at a predetermined angle, and reflecting the signal light into the ophthalmoscope to perform The anterior segment scans the image.

 Wherein the fixation optical system further includes a third dichroic mirror, the third dichroic mirror being located between the ophthalmoscope and the transmission optical path of the refractive adjustment device;

 After the light source signal of the fixation source passes through the refractive adjustment device, it is reflected by the third dichroic mirror and enters the ophthalmoscope.

 The light emitted by the imaging light source of the iris imaging optical system is reflected by the cornea, passes through the ophthalmoscope, and is directly transmitted by the third dichroic mirror and sequentially enters the third lens and the imaging device.

 Correspondingly, an embodiment of the present invention further provides an ophthalmologic OCT imaging method, including:

 When the anterior segment scan imaging is performed, the optical path conversion device converts the signal light emitted from the light source and passed through the collimating mirror and the scanning device to the image containing the ophthalmoscope, the first dichroic mirror and the first according to the received optical path conversion command. In a lens anterior segment probe imaging device, the anterior segment probe imaging device drives the first dichroic mirror to reflect the signal light into the ophthalmoscope to perform anterior segment scan imaging; initial of an ophthalmic OCT system The state is for performing posterior segment scan imaging. After the ophthalmic OCT system completes the anterior segment scan imaging, it will adjust back to the initial state of imaging the posterior segment scan, and evacuate the first dichroic mirror out of the optical path.

Wherein, when performing imaging of the posterior segment of the eye, the optical path conversion device converts the signal light emitted from the light source and passed through the collimating mirror and the scanning device respectively to the second dichroic mirror, and the second dichroic mirror will The signal light is reflected and sequentially enters a refractive adjustment device of the fixation optical system and the ophthalmoscope, Performing posterior segment scan imaging; or

 When performing imaging of the posterior segment of the eye, the optical path conversion device directly converts the signal light emitted from the light source and respectively passed through the collimating mirror and the scanning device to the refractive adjustment device of the fixation optical system and the ophthalmoscope, Perform imaging of the posterior segment of the eye.

 Embodiments of the present invention have the following beneficial effects:

 By setting the optical path conversion device, when the ophthalmic OCT system performs the anterior segment scan imaging, the signal light emitted from the light source and passed through the collimating mirror and the scanning device respectively is converted into the anterior segment probe imaging device to perform the anterior segment of the eye. Scanning imaging enables the ocular anterior segment imaging of the human eye with different visual acuity. The refractive compensation is always kept clear, and the imaging quality of the anterior segment OCT is not affected. The gaze point adjustment and OCT imaging quality in the prior art are solved. The OCT system of the embodiment of the present invention has a simple structure and is convenient to operate. The ophthalmic OCT system of the embodiment of the present invention, the OCT imaging of the posterior segment of the eye is located in the retina of the human eye, and the OCT of the anterior segment of the eye. When the imaging is in the cornea, the anterior segment imaging can be realized by adjusting the optical path of the reference arm. The fixation point can be moved up and down to achieve the adjustment of the human eye gaze position to meet the left and right eye gaze and the macular or optic nerve, room. Different measurements of angles, etc. are required. DRAWINGS

 In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the description of the prior art will be briefly described below. Obviously, the drawings in the following description are only It is a certain embodiment of the present invention, and other drawings can be obtained from those skilled in the art without any inventive labor.

 1 is a schematic structural view of a first embodiment of an ophthalmic OCT system in the prior art;

 2 is a schematic structural view of a second embodiment of an ophthalmic OCT system in the prior art;

 3 is a block diagram showing the structure of a first embodiment of the ophthalmic OCT system of the present invention;

 4 is a block diagram showing the structure of a second embodiment of the ophthalmic OCT system of the present invention;

 5 is a schematic view showing the optical path structure of the first embodiment of the ophthalmic OCT system of the present invention;

 6 is a block diagram showing the structure of a third embodiment of the ophthalmic OCT system of the present invention;

7 is a schematic view showing the optical path structure of the posterior segment OCT system in the ophthalmic OCT system of the present invention; FIG. 8 is a schematic view showing the optical path structure of the fixation optical system in the ophthalmic OCT system of the present invention; FIG. 9 is an anterior segment OCT system in the ophthalmic OCT system of the present invention. Schematic diagram of the optical path structure; 10 is a schematic view showing the optical path structure of the iris imaging optical system in the ophthalmic OCT system of the present invention; FIG. 11 is a schematic view showing the optical path structure of the second embodiment of the ophthalmic OCT system of the present invention;

 12 is a flow chart showing an ophthalmologic OCT imaging method according to an embodiment of the present invention. detailed description

 BRIEF DESCRIPTION OF THE DRAWINGS The technical solutions in the embodiments of the present invention will be described in detail with reference to the accompanying drawings. All other embodiments obtained by a person of ordinary skill in the art based on the embodiments of the present invention without creative work are within the scope of the present invention.

 FIG. 3 is a block diagram showing a first embodiment of the ophthalmic OCT system of the present invention. The ophthalmic OCT system 1 includes a posterior segment OCT imaging system 1a and an anterior segment OCT imaging system 1b. The posterior segment OCT imaging system 1a further includes The optical path conversion device 110, the anterior segment OCT imaging system 1b includes an anterior segment probe imaging device 1b1, and the anterior segment probe imaging device 1b1 includes an ophthalmoscope 115, a first dichroic mirror 118, and a first lens 116, wherein

 When the ophthalmic OCT system 1 performs the anterior segment scan imaging, the optical path conversion device 110 receives the optical path conversion command, and converts the signal light emitted from the light source and passed through the collimating mirror and the scanning device to the anterior segment probe imaging device lbl. The anterior segment probe imaging device lb1 drives the first dichroic mirror 118 to reflect the signal light into the ophthalmoscope 115 for anterior segment scan imaging.

 Specifically, when the ophthalmic OCT system 1 performs the anterior segment scan imaging, the anterior segment probe imaging device lb1 receives the driving command sent by the ophthalmic OCT system 1, and the angle of the first dichroic mirror 118 can be adjusted to reflect the signal light. Entering the ophthalmoscope 115, the first dichroic mirror 118 can also be inserted in front of the ophthalmoscope 115 at an angle to reflect the signal light into the ophthalmoscope 115.

 The optical path conversion device 110 includes, but is not limited to, a rotatably adjustable total reflection mirror, as long as the signal light emitted from the light source and passed through the collimating mirror and the scanning device is converted to the anterior segment probe imaging after receiving the optical path switching instruction. Just in the device lbl.

 Further, as shown in FIG. 4, a block diagram structural diagram of a second embodiment of the ophthalmic OCT system of the present invention, the ophthalmic OCT system 1 includes an ophthalmologic OCT imaging system la and an anterior segment OCT imaging system lb, and may also include fixation Optical system lc and iris imaging optical system Id, wherein

The fixation optical system lc includes a fixation light source 121, a refractive adjustment device 112, a second lens, and an ophthalmoscope 115. The second lens in FIG. 4 is illustrated by including two lenses, a lens 119 and a lens 120; The iris imaging optical system Id includes an imaging light source 124, an imaging device 122, a third lens 123, and an ophthalmoscope 115;

 Specifically, as shown in FIG. 5, the optical path structure of the first embodiment of the ophthalmic OCT system of the present invention, the ophthalmic OCT system 1 further includes a light source 101, a fiber coupler 102, a reference arm 103, a lens 104, a mirror 105, and detection. 106, computer 107, collimating mirror 108, scanning device 109 (which may be an XY-direction scanning device, etc.), second dichroic mirror 111, refractive adjustment device 112, third dichroic mirror 113, mirror 114, a mirror 117, a first dichroic mirror 118 and a light source 124 in the iris imaging optical system Id;

 It should be noted that, in the embodiment of FIG. 3 and FIG. 4, the posterior segment OCT imaging system 1a may further include an ophthalmoscope 115, a collimating mirror, a scanning device, a refractive adjustment device, and a mirror, etc., but only FIG. 3 and Not fully shown in FIG. 4; the anterior segment probe imaging device 1b1 may further include an optical path conversion device 110. That is, the target OCT system 1 in the embodiment of the present invention includes the optical path conversion device 110, and the optical path conversion device 110 may belong to the posterior segment OCT imaging system 1a, may also belong to the anterior segment OCT imaging system 1b, or may belong to the eye at the same time. The posterior segment OCT imaging system la and the anterior segment OCT imaging system lb. Specifically, a block diagram structural diagram of a third embodiment of the ophthalmic OCT system of the present invention as shown in FIG. 6; the posterior segment OCT imaging system 1a may include an optical path conversion device 110, and the anterior segment OCT imaging system 1b also includes an optical path conversion device 110. .

 Next, the ophthalmic OCT system of the present invention is decomposed into an OCT system la, a fixation optical system lc, an anterior segment OCT system lb, and an iris imaging optical system Id for detailed description:

 FIG. 7 is a schematic diagram showing the optical path structure of the posterior segment OCT system in the ophthalmic OCT system of the present invention, and the second dichroic mirror 111 is located between the refractive adjustment device 112 and the transmission optical path of the lens 119; when the ophthalmic OCT system 1 performs When the posterior segment scans the image, the optical path conversion device 110 receives the optical path conversion command sent by the system, adjusts the angle of the reflected light of the optical path conversion device 110, and adjusts the incident light to the reflected light perpendicularly and upwardly as shown in FIG. The signal light emitted by the light source 101 and passing through the collimating mirror 108 and the scanning device 109 respectively is converted to the second dichroic mirror 111, and the second dichroic mirror 111 reflects the signal light and sequentially enters the diopter adjusting device. 112 and the ophthalmoscope 115 (specifically, the refractive adjustment device 112, the third dichroic mirror 113, the mirror 114, and the ophthalmoscope 115 are sequentially passed) to perform imaging of the posterior segment of the eye.

Specifically, the optical path conversion device 110 in the ophthalmic OCT system may perform conversion of the anterior segment scan imaging according to the received instruction, or perform conversion of the posterior segment scan imaging; the ophthalmology in the embodiment of the present invention The OCT system can also set the initial state for the posterior segment scan imaging. When the ophthalmic OCT system needs to perform the anterior segment scan imaging, the optical path conversion device 110 performs the conversion according to the received instruction, when the ophthalmic OCT system completes the anterior segment scan imaging. , the initial state of the imaging of the posterior segment of the eye is automatically adjusted back, that is, the state in which the optical path conversion device 110 automatically converts to perform imaging of the posterior segment of the eye, and the first dichroic mirror is evacuated from the optical path.

 Specifically, the posterior segment OCT system 1a includes a collimating mirror 108, a scanning device 109, an optical path converting device 110, a second dichroic mirror 111, a refractive adjustment device 112, a third dichroic mirror 113, and a mirror. 114 and an ophthalmoscope probe imaging device lal composed of an ophthalmoscope 115; the light source 101 in the posterior segment OCT imaging optical path includes a weak coherent light source, and the outputted light thereof passes through the fiber coupler 102 to the posterior segment probe imaging device 1a and the reference arm 103. Provide light. The reference arm 103 has a known length and reflects light back into the fiber coupler 102 through the mirror 105. The posterior segment probe imaging device lal supplies light to the subject's eye E, and the light scattered from the posterior segment probe imaging device 1al interferes with the reflected light of the reference arm 103 in the fiber coupler 102, and the interference light is detected by the detector. 106 is detected, processed by calculator 107, and finally displayed.

 It should be noted that the output wavelength of the light source 101 includes, but is not limited to, near-infrared light of about 815-865 nm.

 FIG. 8 is a schematic diagram showing the optical path structure of the fixation optical system in the ophthalmic OCT system of the present invention. After the light source signal of the fixation light source 121 passes through the lens 120 and the lens 119 in sequence, it is directly transmitted by the second dichroic mirror 111 and sequentially passes through. The refractive adjustment device 112, the third dichroic mirror 113, the mirror 114, and the ophthalmoscope 115 finally enter the human eye E.

 Specifically, the fixation light source 121 in the fixation optical system lc may be an LCD to display a fixation mark (internal fixation mark) for fixation of the human eye E to be inspected. The light from the LCD is focused by the lens 120, transmitted by the second dichroic mirror 111, subjected to refractive compensation by the refractive adjustment device 112, and then reflected by the third dichroic mirror 113 to the mirror 114, and finally passes through the fundus. The mirror 115 is incident on the subject's eye E; thus, the internal fixation target is projected onto the fundus of the subject's eye E. It should be noted that the LCD is only an example, and the fixation light source 121 can also use other fixation devices, such as a plurality of LEDs arranged side by side, etc.; the fixation optical system lc in the embodiment of the present invention can use the internal fixation target thereof. To change the fixation position of the eye E to be inspected, the internal fixation target can be moved up and down and left and right to meet the detection of different positions of the human eye.

FIG. 9 is a schematic diagram showing the optical path structure of the anterior segment OCT system in the ophthalmic OCT system of the present invention. The first dichroic mirror 118 is located between the ophthalmoscope 115 and the transmission optical path of the refractive adjustment device 112. The first dichroic mirror 118 is located between the fundus mirror 115 and the transmission optical path of the mirror 114; the anterior segment probe imaging device 1b1 in the anterior segment OCT system 1b can be composed of the collimating mirror 108, the scanning device 109, The optical path conversion device 110, the lens 116, the mirror 117, the first dichroic mirror 118, and the fundus mirror 115; when the ophthalmic OCT system 1 performs the anterior segment scan imaging, the optical path conversion device 110 adjusts the optical path after receiving the optical path conversion command The angle of the reflected light of the conversion device 110 is adjusted so that the incident light is perpendicular to the reflected light and reflected downward, as shown in FIG. 9, so that the signal light emitted from the light source 101 and passed through the collimator lens 108 and the scanning device 109 respectively is converted to the front of the eye. After the lens 116 of the probe imaging device lb1, at the same time, the anterior segment probe imaging device 1b1 receives the driving command sent by the ophthalmic OCT system 1, the angle of the first dichroic mirror 118 can be adjusted to reflect the signal light into the fundus. The mirror 115 can also insert the first dichroic mirror 118 in front of the ophthalmoscope 115 at an angle, that is, insert the first dichroic mirror 118 into the ophthalmoscope 115 at an angle. Between the transmission path of the mirror 114 and the reflected light path, the signal light is reflected into the ophthalmoscope 115 for anterior segment scan imaging.

 It should be noted that the signal light passing through the collimating mirror 108 and the scanning device 109 respectively may sequentially pass through the plurality of lenses 116 and the mirror 117 to reach the first dichroic mirror 118, as shown in FIG. The signal light after the 108 and the scanning device 109 passes through the lens 116 and the mirror 117 in sequence, and the lens 116a and the mirror 117a reach the first dichroic mirror 118, and the signal light is reflected by the first dichroic mirror 118 into the fundus mirror 115. , for imaging of the anterior segment scan.

 It should be noted that, in the anterior segment OCT system in the embodiment of the present invention, the lens 116, the mirror 117, and the lens 116a constitute an afocal system, so that the scanning optical path diverges at the scanning device 109 in the anterior segment probe imaging device 1b1. The back focus of the ophthalmoscope 115 can be concentrated, and the parallel entering OCT can still pass through the back focus of the ophthalmoscope 115 in parallel, that is, the center point of the scanning device 109 is conjugate with the back focus of the ophthalmoscope 115, and the optical path is symmetrically designed.

 FIG. 10 is a schematic diagram showing the optical path structure of the iris imaging optical system in the ophthalmic OCT system of the present invention. The light emitted by the imaging light source 124 in the iris imaging optical system Id passes through the cornea 115 after being reflected by the cornea, and then enters the lens 123 and the camera sequentially. Device 122.

 Specifically, the image light source 124 includes light emitted by 1124a and 123b (which may be visible light of 780 nm) to illuminate the cornea of the human eye E to be examined, and is reflected at the cornea. The reflected light passes through the ophthalmoscope 115, directly enters the mirror 114, and the mirror 114 reflects into the third dichroic mirror 113, and is directly transmitted by the third dichroic mirror 113 into the lens 123, and finally captured by the imaging device 122;

It should be noted that the examiner uses the lower squatting device to fix the eye to be inspected, so that it is from the fixation optical system. The fixation mark in the system lc is fixed in the eye to be inspected, and then the examiner controls the movement of the lower jaw device by the operation lever while observing the display screen of the computer 107, so that the cornea of the eye E to be inspected enters the imaging device 122. And the cornea image is presented in the display screen of the computer 107.

 The optical path structure of the ophthalmic OCT system in the embodiment of the present invention includes, but is not limited to, the optical path structure shown in FIG. 3, and the optical path structure of the second embodiment of the ophthalmic OCT system of the present invention as shown in FIG. Designed to reduce the number of mirrors and simplify the light path. specifically:

 When the ophthalmic OCT system 1 performs imaging of the posterior segment of the eye, the optical path conversion device 110 will cause the incident light to be perpendicular to the reflected light and reflected upward as shown in FIG. 11, so that the light emitted from the light source 101 passes through the collimating mirror 108 and The signal light after the scanning device 109 is converted to the refractive adjustment device 112 and the ophthalmoscope 115 for imaging of the posterior segment of the eye; specifically, the signal light emitted from the light source 101 and passing through the collimating mirror 108 and the scanning device 109, respectively. The conversion to the refractive adjustment device 112 and the third dichroic mirror 113 is reflected by the third dichroic mirror 113 to the ophthalmoscope 115 for imaging of the posterior segment of the eye. When the ophthalmic OCT system 1 performs imaging of the posterior segment of the eye, the ophthalmic OCT system 1 evacuates the first dichroic mirror 118 between the refractive adjustment device 112 and the transmission optical path of the fundus mirror 115, for example, the first dichroic color can be The mirror 118 is horizontally horizontally disposed so that the signal light directly enters the fundus mirror 115 from the third dichroic mirror 113 for imaging of the posterior segment of the eye;

 When the ophthalmic OCT system 1 performs the anterior segment scan imaging, the optical path conversion device 110 adjusts the reflected light angle of the optical path conversion device 110 after receiving the optical path conversion command, for example, rotates 45 degrees counterclockwise in a preset direction, and can also convert the optical path. The device 110 is evacuated between the scanning device 109 and the transmission optical path of the lens 116, so that the signal light emitted from the light source 101 and passing through the collimating mirror 108 and the scanning device 109 respectively is converted to the lens 116 of the anterior segment probe imaging device. The anterior segment probe imaging device receives the drive command sent by the ophthalmic OCT system 1 and inserts the first dichroic mirror 118 in front of the ophthalmoscope 115 at a predetermined angle, that is, inserts the first dichroic mirror 118 into the fundus at an angle. Between the transmission path of the mirror 115 and the third dichroic mirror 113, the signal light is reflected into the ophthalmoscope 115 for anterior segment scan imaging.

 The embodiment of Fig. 11 reduces the second dichroic mirror 111 and the mirror 114 more than the embodiment of Fig. 9, simplifying the optical path. The embodiment of the present invention is not limited to the optical path structure of FIG. 9 or FIG. 11, and the optical path structure of FIG. 9 or FIG. 11 is only a preferred embodiment, and thus equivalent changes made according to the claims of the present invention are still covered by the present invention;

It should be noted that the optical path conversion device 110 is a rotatably adjustable total reflection mirror, and the ophthalmic OCT When the system 1 performs the anterior segment scan imaging, the optical path conversion device 110 can rotate the preset angle according to the design of the optical path after receiving the optical path conversion instruction, that is, adjust the position according to the requirements of the current optical path structure design, for example, in the embodiment of FIG. Rotating clockwise by 90 degrees, the embodiment of FIG. 11 rotates counterclockwise by 45 degrees, and the signal light emitted from the light source 101 and passed through the collimator lens 108 and the scanning device 109, respectively, is converted into the anterior segment probe imaging device. The first dichroic mirror 118 is inserted between the ophthalmoscope 115 and the transmission optical path of the third dichroic mirror 113 at an angle, and reflects the signal light into the ophthalmoscope 115 for imaging of the anterior segment scan. And after the anterior segment scan imaging is completed, the ophthalmic OCT system 1 can automatically convert the optical path conversion device 110 into a state in which the posterior segment scan imaging is performed, that is, for example, the optical path conversion device 110 is automatically rotated 90 degrees counterclockwise in the embodiment of FIG. In the embodiment, the optical path conversion device 110 is automatically rotated 45 degrees by the hand to adjust the initial state of the posterior segment scan imaging, and the first dichroic mirror 118 is evacuated from the optical path.

 It should be noted that, after the optical path conversion device 110 receives the optical path conversion command, the predetermined angle of rotation according to the design of the optical path includes not limited to 90 degrees of clockwise rotation in the embodiment of FIG. 9 or 45 degrees of counterclockwise rotation in the embodiment of FIG. And so on, as long as the optical path conversion device 110 rotates the predetermined angle according to the design of the optical path to complete the conversion of the optical path.

 The second dichroic mirror 111 in the embodiment of the present invention can reflect the signal light (the wavelength can be about 800-880 nm) emitted by the light source 101 in the ophthalmic OCT system 1, and the fixed light source 121 from the fixation optical system lc. Transmission of fixation light (wavelength can be 550 nm);

 The first dichroic mirror 118 can reflect the signal light transmitted from the anterior segment probe imaging device lb1, and can also reflect the fixation light from the fixation light source 121 in the fixation optical system lc, and can also The illumination light (the wavelength may be about 780 nm) emitted by the light source 124 in the iris imaging optical system Id is transmitted;

 The third dichroic mirror 113 can not only reflect the signal light emitted by the light source 101 in the ophthalmic OCT system 1, but also reflect the fixation light from the fixation light source 121 in the fixation optical system lc, and can also The illumination light emitted by the light source 124 in the iris imaging optical system Id is transmitted;

 In the posterior segment OCT imaging system of the embodiment of the present invention, the posterior segment probe imaging device lal and the fixation optical path both require the refractive adjustment device 112, so that the fixation optical path and the fundus imaging optical path share the same refractive adjustment device 112; In the section OCT imaging system, the anterior segment probe imaging device lbb does not require the refractive adjustment device 112, and the fixation optical path requires the refractive adjustment device 112.

Embodiments of the present invention are implemented by setting an optical path conversion device to perform an anterior segment of the eye in an ophthalmic OCT system When scanning imaging, the signal light emitted from the light source and passing through the collimating mirror and the scanning device respectively is converted into the anterior segment probe imaging device to perform anterior segment scan imaging, and the human eye for different vision is performed. In the imaging, the refractive compensation is always kept clear, and the imaging quality of the anterior segment OCT is not affected, which solves the problem that the gaze point adjustment and the OCT imaging quality are not well matched in the prior art; The OCT system of the ophthalmology is simple in structure and convenient to operate. According to the OCT system of the embodiment of the present invention, the optical path surface of the ophthalmologic OCT is located in the retina of the human eye, and the optical path surface of the anterior segment OCT is located in the cornea, without adjusting the reference. The optical path of the arm is used to realize the imaging of the anterior segment of the eye; the gaze point can be moved up and down to achieve the adjustment of the gaze position of the human eye, so as to meet the different measurement needs of the left and right eye gaze and the measurement of the macula or the optic nerve, the anterior chamber and the like.

 The structure of the ophthalmic OCT system of the embodiment of the present invention is described in detail above, and the ophthalmic OCT imaging method of the embodiment of the present invention will be described in detail below.

 FIG. 12 is a schematic flowchart diagram of an ophthalmologic OCT imaging method according to an embodiment of the present invention, including step S1201: when performing anterior segment scan imaging, the optical path conversion device emits light from the light source according to the received optical path conversion instruction, respectively The signal light after the straight mirror and the scanning device is converted into an anterior segment probe imaging device including a first lens, a first dichroic mirror and an ophthalmoscope, the anterior segment probe imaging device driving the first dichroic mirror The signal light is reflected into the ophthalmoscope to perform anterior segment scan imaging;

 Step S1202: The initial state of the ophthalmic OCT system is to perform imaging of the posterior segment of the eye. After the ophthalmic OCT system completes the imaging of the anterior segment of the eye, the initial state of the posterior segment scan imaging is adjusted, and the first dichroic color is obtained. The mirror leaves the light path.

 Specifically, the optical path conversion device includes, but is not limited to, a rotatably-adjustable total reflection mirror, and the signal light emitted from the light source and passed through the collimating mirror and the scanning device is converted to the anterior segment of the eye as long as the optical path conversion command is received. The probe imaging device can be used.

Further, the ophthalmic OCT imaging method of the embodiment of the present invention further includes: when performing imaging of the posterior segment of the eye, the optical path conversion device converts the signal light emitted from the light source and respectively passed through the collimating mirror and the scanning device to the second a dichroic mirror, the second dichroic mirror reflects the signal light and sequentially enters a refractive adjustment device of the fixation optical system and the ophthalmoscope to perform imaging of the posterior segment of the eye; or when performing an eye In the posterior segment scanning imaging, the optical path conversion device directly converts the signal light emitted from the light source and passed through the collimating mirror and the scanning device to the refractive adjustment device of the fixation optical system and the ophthalmoscope, respectively, to perform the posterior Section scan imaging. The flow of the ophthalmic OCT imaging method of the embodiment of the present invention may be referred to the above detailed description of the ophthalmic OCT system.

 In summary, by setting the optical path conversion device, when the ophthalmic OCT system performs the anterior segment scan imaging, the signal light emitted from the light source and passed through the collimating mirror and the scanning device respectively is converted into the anterior segment probe imaging device. For the anterior segment scan imaging, when the anterior segment imaging is performed for the human eye with different visual acuity, the refractive compensation is always kept clear, and the imaging quality of the anterior segment OCT is not affected, and the gaze point in the prior art is solved. The OCT imaging system of the embodiment of the present invention has a simple structure and is convenient to operate. The ophthalmic OCT system of the embodiment of the present invention has an optical path surface in the human eye. Retina, OCT imaging in the anterior segment of the eye is located in the cornea, without adjusting the optical path of the reference arm to achieve anterior segment imaging; gaze points can be moved up and down to achieve eye gaze position adjustment, to meet left and right eye gaze and measurement Different measurement needs of the macula or optic nerve, angle, etc. This may be accomplished by a computer program instructing the associated hardware, which may be stored in a computer readable storage medium, which, when executed, may include the flow of an embodiment of the methods described above. The storage medium may be a magnetic disk, an optical disk, a read-only memory (ROM), or a random access memory (RAM).

 The above description is only a preferred embodiment of the present invention, and the scope of the present invention is not limited thereto, and the equivalent changes made by the claims of the present invention are still within the scope of the present invention.

Claims

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What is claimed is: 1. An ophthalmic OCT system, comprising: an posterior segment OCT imaging system and an anterior segment OCT imaging system, the posterior segment OCT imaging system comprising an optical path conversion device, the anterior segment OCT imaging system comprising an anterior segment probe An imaging device, the anterior segment probe imaging device comprising an ophthalmoscope, a first dichroic mirror and a first lens, wherein

 When the ophthalmic OCT system performs the anterior segment scan imaging, the optical path conversion device converts the signal light emitted from the light source and passed through the collimating mirror and the scanning device to the anterior segment probe imaging after receiving the optical path switching instruction. In the device;

 The anterior segment probe imaging device drives the first dichroic mirror to reflect the signal light into the ophthalmoscope for anterior segment scan imaging.

2. The ophthalmic OCT system according to claim 1, further comprising a fixation optical system and an iris imaging optical system, wherein

 The fixation optical system includes a fixation light source, a refractive adjustment device, a second lens, and the ophthalmoscope;

 The iris imaging optical system includes an imaging light source, an imaging device, a third lens, and the ophthalmoscope.

3. The ophthalmic OCT system according to claim 2, wherein the initial state of the ophthalmic OCT system is for performing posterior segment scan imaging, and the ophthalmic OCT system performs adjustment of the anterior segment scan image, and then adjusts back to the posterior segment of the eye. Scanning the initial state of imaging, the first dichroic mirror is evacuated out of the optical path.

4. The ophthalmic OCT system of claim 3, wherein the posterior segment OCT imaging system further comprises a second dichroic mirror, the second dichroic mirror being located in the refractive adjustment device and Between the transmission optical paths of the second lens;

When the ophthalmic OCT system performs imaging of the posterior segment of the eye, the optical path conversion device converts signal light emitted from the light source and passed through the collimating mirror and the scanning device to the second dichroic mirror, a dichroic mirror reflects the signal light and sequentially enters the refractive adjustment device and the ophthalmoscope to perform imaging of the posterior segment of the eye; or The optical path conversion device directly converts signal light emitted from the light source and respectively passed through the collimating mirror and the scanning device to the refractive adjustment device and the ophthalmoscope to perform imaging of the posterior segment of the eye.

The ophthalmic OCT system according to claim 3, wherein the light source signal of the fixation source passes through the second lens, is directly transmitted by the second dichroic mirror, and sequentially enters the bend Light adjustment device and the ophthalmoscope.

6. The ophthalmic OCT system according to claim 3, wherein the optical path conversion device is a rotationally adjustable total reflection mirror;

 When the ophthalmic OCT system performs the anterior segment scan imaging, the optical path conversion device rotates the preset angle according to the design of the optical path after receiving the optical path conversion command, and the signal emitted from the light source and passed through the collimating mirror and the scanning device respectively Converting light into the anterior segment probe imaging device; the anterior segment probe imaging device driving the first dichroic mirror to insert an optical path at a predetermined angle, and reflecting the signal light into the ophthalmoscope to perform The anterior segment scans the image.

7. The ophthalmic OCT system according to claim 3, wherein the fixation optical system further comprises a third dichroic mirror, the third dichroic mirror being located in the ophthalmoscope and the refraction Adjusting the transmission path between the devices;

 After the light source signal of the fixation source passes through the refractive adjustment device, it is reflected by the third dichroic mirror and enters the ophthalmoscope.

The ophthalmic OCT system according to claim 7, wherein the light emitted by the imaging light source of the iris imaging optical system is reflected by the cornea and passes through the ophthalmoscope, and is directly transmitted by the third dichroic mirror. And sequentially entering the third lens and the imaging device.

9. An ophthalmic OCT imaging method, comprising:

When the anterior segment scan imaging is performed, the optical path conversion device converts the signal light emitted from the light source and passed through the collimating mirror and the scanning device to the image containing the ophthalmoscope, the first dichroic mirror and the first according to the received optical path conversion command. In a lens anterior segment probe imaging device, the anterior segment probe imaging device drives the first dichroic mirror to reflect the signal light into the ophthalmoscope to perform anterior segment scan imaging; The initial state of the ophthalmic OCT system is to perform imaging of the posterior segment of the eye. After the ophthalmic OCT system completes the imaging of the anterior segment of the eye, it will adjust back to the initial state of imaging of the posterior segment of the eye, and evacuate the first dichroic mirror. Light path.

10. The ophthalmic OCT imaging method according to claim 9, wherein when performing imaging of the posterior segment of the eye, the optical path conversion device converts the signal light emitted from the light source and passed through the collimating mirror and the scanning device respectively to a second dichroic mirror, the second dichroic mirror reflects the signal light and sequentially enters a refractive adjustment device of the fixation optical system and the ophthalmoscope to perform imaging of the posterior segment of the eye; or

 When performing imaging of the posterior segment of the eye, the optical path conversion device directly converts the signal light emitted from the light source and respectively passed through the collimating mirror and the scanning device to the refractive adjustment device of the fixation optical system and the ophthalmoscope, Perform imaging of the posterior segment of the eye.