CN102438505B - Ophthalmology OCT system and ophthalmology OCT imaging method - Google Patents
Ophthalmology OCT system and ophthalmology OCT imaging method Download PDFInfo
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- CN102438505B CN102438505B CN2011800017967A CN201180001796A CN102438505B CN 102438505 B CN102438505 B CN 102438505B CN 2011800017967 A CN2011800017967 A CN 2011800017967A CN 201180001796 A CN201180001796 A CN 201180001796A CN 102438505 B CN102438505 B CN 102438505B
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Abstract
The embodiment of the invention discloses an ophthalmology OCT system, comprising a posterior segment intraocular OCT imaging system and an anterior eye segment OCT imaging system. The posterior segment intraocular OCT imaging system comprises a light path conversion device, the anterior eye segment OCT imaging system comprises an anterior eye segment probe imaging device comprising an ophthalmoscope, a first dichroscope and a first lens; wherein, when the ophthalmology OCT system carries out an anterior eye segment scanning imaging, and after the light path conversion device receives a light path conversion instruction, signal light passing through a collimating mirror and a scanning device respectively are converted to the anterior eye segment probe imaging device; the anterior eye segment probe imaging device drives the first dichroscope to reflect the signal light to the ophthalmoscope to carry out the anterior eye segment scanning imaging. Correspondingly, the invention also discloses an ophthalmology OCT imaging method. By employing the invention, when the anterior eye segment imaging is carried out on human eye, fixation points can always be kept clear via refractive compensation, and the anterior eye segment probe imaging quality is not affected.
Description
Technical field
The present invention relates to optoelectronic areas, relate in particular to a kind of ophthalmology OCT system and a kind of ophthalmology OCT formation method.
Background technology
Optical coherent chromatographic imaging (OCT, Optical Coherence Tomography) is a kind of emerging optical image technology, with respect to traditional clinical imaging means, having the advantages such as resolution height, image taking speed, radiationless damage, moderate cost, compact conformation, is the important potential instrument of basic medical research and clinical diagnostic applications.Current, in multiple optical Ophthalmologic apparatus, the OCT device that is used for ophthalmologic examination and treatment has become the indispensable Ophthalmologic apparatus of eye disease diagnosis.
Patent documentation US2009/0168017A1 discloses the OCT device of realizing the anterior ocular segment imaging in a kind of oculi posterior segment OCT system, as shown in Figure 1, realize the anterior ocular segment imaging at lens of sample arm scanning galvanometer 130 rear insertions 132, because the diopter of measurand is different, such as myopia and hypermetropia, can clearly imaging on the human eye retina in order to ensure point of fixation, the Diopter accommodation device need to be arranged, so this system watch light path attentively and the anterior ocular segment imaging optical path shares the Diopter accommodation device; Anterior ocular segment OCT imaging optical path need not Diopter accommodation, point of fixation can be at the optical fundus blur-free imaging and in order to ensure watching attentively in the light path, need to carry out Diopter accommodation, and this system adopts and to move forward and backward ophthalmoscopic mode and realize dioptric adjusting, yet, anterior ocular segment OCT imaging optical path is shared ophthalmoscopic with watching light path attentively, when ophthalmofundoscope is moved, though can so that point of fixation at the optical fundus blur-free imaging, but can affect anterior ocular segment OCT image quality, point of fixation regulate with the OCT image quality between be difficult to reach simultaneously optimum state, have the problem that point of fixation is regulated and the OCT image quality can not fine coupling.And ophthalmoscopic movement, being difficult to guarantee scan light necessarily perpendicular to cornea (scanning light beam is perpendicular to cornea as can be known from document width of cloth figure), this will bring very large difficulty for the rectification of image, affected the image quality of OCT.
Patent documentation US2008/0106696A1 discloses the another kind of OCT system that realizes the anterior ocular segment imaging function in the oculi posterior segment system, as shown in Figure 2, realize by the mode that increases an anterior ocular segment mirror 770 in ophthalmofundoscope 750,760 back, during joint imaging before eyes, what adopt is the scan pattern of vertical cornea, this mode also be faced with point of fixation regulate can not fine coupling with the OCT image quality problem, and this mode is very high for the designing requirement of camera lens, realizes difficulty.
Because, the diopter of different human eyes is different in the actual life, such as myopia and hypermetropia, when being tested, eyes often need the additional diopter that carries out to regulate, when how in oculi posterior segment OCT system, realizing the anterior ocular segment imaging function for the human eye of different visions, can carry out refraction compensation and remain that point of fixation is clear, not affect again the image quality of anterior ocular segment OCT, be the hot issue that people study always.
Summary of the invention
Embodiment of the invention technical problem to be solved is, a kind of ophthalmology OCT system and a kind of ophthalmology OCT formation method are provided, can solve point of fixation in the prior art regulate can not fine coupling with the OCT image quality problem, and system structure is simple, easy to operate.
In order to solve the problems of the technologies described above, the embodiment of the invention provides a kind of ophthalmology OCT system, comprise oculi posterior segment OCT imaging system and anterior ocular segment OCT imaging system, described oculi posterior segment OCT imaging system comprises optical path switching device, described anterior ocular segment OCT imaging system comprises anterior ocular segment probe imaging device, described anterior ocular segment probe imaging device contains ophthalmofundoscope, the first dichroic mirror and first lens, wherein
When described ophthalmology OCT system carries out the anterior ocular segment scanning imagery, after described optical path switching device receives the light path converting instruction, will send from light source, be transformed in the described anterior ocular segment probe imaging device through the flashlight behind collimating mirror and the scanning means respectively;
Described anterior ocular segment probe imaging device drives described the first dichroic mirror described flashlight reflection is entered described ophthalmofundoscope, to carry out the anterior ocular segment scanning imagery.
Wherein, described ophthalmology OCT system also comprises solid optometry system and iris image pickup optical system, wherein
Described solid optometry system comprises looks light source, Diopter accommodation device, the second lens and described ophthalmofundoscope admittedly;
Described iris image pickup optical system comprises pickup-light source, camera head, the 3rd lens and described ophthalmofundoscope.
Wherein, the original state of ophthalmology OCT system is for carrying out the oculi posterior segment scanning imagery, after described ophthalmology OCT system finishes the anterior ocular segment scanning imagery, with the original state of adjusting back into row oculi posterior segment scanning imagery, described the first dichroic mirror withdrawn out light path.
Wherein, described oculi posterior segment OCT imaging system also comprises the second dichroic mirror, and described the second dichroic mirror is between the transmission light path of described Diopter accommodation device and described the second lens; Wherein
When described ophthalmology OCT system carries out the oculi posterior segment scanning imagery, described optical path switching device will send from light source, be transformed into described the second dichroic mirror through the flashlight behind collimating mirror and the scanning means respectively, described the second dichroic mirror reflects described flashlight and enters successively described Diopter accommodation device and described ophthalmofundoscope, to carry out the oculi posterior segment scanning imagery; Perhaps
Described optical path switching device will send from light source, directly be transformed into successively described Diopter accommodation device and described ophthalmofundoscope through the flashlight behind collimating mirror and the scanning means respectively, carrying out the oculi posterior segment scanning imagery.
Wherein, the described light signal of admittedly looking light source is directly also entered described Diopter accommodation device and described ophthalmofundoscope by described the second dichroic mirror transmission successively through behind described the second lens.
Wherein, described optical path switching device is the completely reflecting mirror of rotatable adjusting;
When described ophthalmology OCT system carries out the anterior ocular segment scanning imagery, described optical path switching device rotates default angle according to the design of light path after receiving the light path converting instruction, to send from light source, be transformed in the described anterior ocular segment probe imaging device through the flashlight behind collimating mirror and the scanning means respectively; Described anterior ocular segment probe imaging device drives described the first dichroic mirror and inserts light path according to default angle, described flashlight reflection is entered described ophthalmofundoscope, to carry out the anterior ocular segment scanning imagery.
Wherein, described solid optometry system also comprises the 3rd dichroic mirror, and described the 3rd dichroic mirror is between the transmission light path of described ophthalmofundoscope and described Diopter accommodation device; Wherein
The described light signal of admittedly looking light source is through behind the described Diopter accommodation device, by described the 3rd dichroic mirror reflects and enter described ophthalmofundoscope.
Wherein, the light that the pickup-light source of described iris image pickup optical system sends through described ophthalmofundoscope, is directly also entered described the 3rd lens and described camera head by described the 3rd dichroic mirror transmission successively after corneal reflex.
Correspondingly, the embodiment of the invention also provides a kind of ophthalmology OCT formation method, comprising:
When carrying out the anterior ocular segment scanning imagery, optical path switching device is according to the light path converting instruction that receives, to send from light source, be transformed in the anterior ocular segment probe imaging device that contains ophthalmofundoscope, the first dichroic mirror and first lens through the flashlight behind collimating mirror and the scanning means respectively, described anterior ocular segment probe imaging device drives described the first dichroic mirror described flashlight reflection is entered described ophthalmofundoscope, to carry out the anterior ocular segment scanning imagery;
The original state of ophthalmology OCT system is for carrying out the oculi posterior segment scanning imagery, after described ophthalmology OCT system finishes the anterior ocular segment scanning imagery, with the original state of adjusting back into row oculi posterior segment scanning imagery, described the first dichroic mirror withdrawn out light path.
Wherein, when carrying out the oculi posterior segment scanning imagery, optical path switching device will send from light source, be transformed into the second dichroic mirror through the flashlight behind collimating mirror and the scanning means respectively, described the second dichroic mirror reflects described flashlight and enters successively Diopter accommodation device and the described ophthalmofundoscope of solid optometry system, to carry out the oculi posterior segment scanning imagery; Perhaps
When carrying out the oculi posterior segment scanning imagery, optical path switching device will send from light source, directly be transformed into successively respectively Diopter accommodation device and the described ophthalmofundoscope of solid optometry system through the flashlight behind collimating mirror and the scanning means, carrying out the oculi posterior segment scanning imagery.
Implement the embodiment of the invention, have following beneficial effect:
By optical path switching device is set, when ophthalmology OCT system carries out the anterior ocular segment scanning imagery, to send from light source, be transformed in the described anterior ocular segment probe imaging device through the flashlight behind collimating mirror and the scanning means respectively, to carry out the anterior ocular segment scanning imagery, when having realized that human eye for different visions carries out the anterior ocular segment imaging, both carried out refraction compensation and remained that point of fixation was clear, do not affect again the image quality of anterior ocular segment OCT, solve point of fixation in the prior art regulate can not fine coupling with the OCT image quality problem; And the ophthalmology OCT system structure of the embodiment of the invention is simple, easy to operate, ophthalmology OCT system by the embodiment of the invention, Aplanatic Surface is positioned at the human eye retina during oculi posterior segment OCT imaging, Aplanatic Surface is positioned at cornea during anterior ocular segment OCT imaging, need not to realize the anterior ocular segment imaging by the light path of regulating reference arm; Point of fixation can about move up and down to realize that human eye watches the adjusting of position attentively, watch and survey the different measuring needs at macula lutea or optic nerve, angle, room etc. attentively to satisfy right and left eyes.
Description of drawings
In order to be illustrated more clearly in the embodiment of the invention or technical scheme of the prior art, the below will do to introduce simply to the accompanying drawing of required use in embodiment or the description of the Prior Art, apparently, accompanying drawing in the following describes only is some embodiments of the present invention, for those of ordinary skills, under the prerequisite of not paying creative work, can also obtain according to these accompanying drawings other accompanying drawing.
Fig. 1 is the structural representation of the first embodiment of ophthalmology OCT system in the prior art;
Fig. 2 is the structural representation of the second embodiment of ophthalmology OCT system in the prior art;
Fig. 3 is the structure of block diagram sketch map of the first embodiment of ophthalmology OCT of the present invention system;
Fig. 4 is the structure of block diagram sketch map of the second embodiment of ophthalmology OCT of the present invention system;
Fig. 5 is the light channel structure sketch map of the first embodiment of ophthalmology OCT of the present invention system;
Fig. 6 is the structure of block diagram sketch map of the 3rd embodiment of ophthalmology OCT of the present invention system;
Fig. 7 is the light channel structure sketch map of oculi posterior segment OCT system in the ophthalmology OCT of the present invention system;
Fig. 8 is the light channel structure sketch map of solid optometry system in the ophthalmology OCT of the present invention system;
Fig. 9 is the light channel structure sketch map of anterior ocular segment OCT system in the ophthalmology OCT of the present invention system;
Figure 10 is the light channel structure sketch map of iris image pickup optical system in the ophthalmology OCT of the present invention system;
Figure 11 is the light channel structure sketch map of the second embodiment of ophthalmology OCT of the present invention system;
Figure 12 is the schematic flow sheet of the ophthalmology OCT formation method of the embodiment of the invention.
The specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the invention, the technical scheme in the embodiment of the invention is clearly and completely described, obviously, described embodiment only is the present invention's part embodiment, rather than whole embodiment.Based on the embodiment among the present invention, those of ordinary skills belong to the scope of protection of the invention not making the every other embodiment that obtains under the creative work prerequisite.
The structure of block diagram sketch map of the first embodiment of ophthalmology OCT of the present invention as shown in Figure 3 system, ophthalmology OCT system 1 comprises oculi posterior segment OCT imaging system 1a and anterior ocular segment OCT imaging system 1b, oculi posterior segment OCT imaging system 1a also comprises optical path switching device 110, anterior ocular segment OCT imaging system 1b comprises anterior ocular segment probe imaging device 1b1, anterior ocular segment probe imaging device 1b1 contains ophthalmofundoscope 115, the first dichroic mirror 118 and first lens 116, wherein
When ophthalmology OCT system 1 carries out the anterior ocular segment scanning imagery, after optical path switching device 110 receives the light path converting instruction, to send from light source, be transformed among the anterior ocular segment probe imaging device 1b1 through the flashlight behind collimating mirror and the scanning means respectively, anterior ocular segment probe imaging device 1b1 drives the first dichroic mirror 118 described flashlight is reflected into into ophthalmofundoscope 115, to carry out the anterior ocular segment scanning imagery.
Particularly, when ophthalmology OCT system 1 carries out the anterior ocular segment scanning imagery, anterior ocular segment probe imaging device 1b1 receives the driving instruction that ophthalmology OCT system 1 sends, can adjust the angle of the first dichroic mirror 118, so that described flashlight is reflected into into ophthalmofundoscope 115, also the first dichroic mirror 118 can be inserted at a certain angle the place ahead of ophthalmofundoscope 115, so that described flashlight is reflected into into ophthalmofundoscope 115.
Optical path switching device 110 includes but not limited to the completely reflecting mirror of rotatable adjusting, as long as after realizing receiving the light path converting instruction, to send from light source, and be transformed among the anterior ocular segment probe imaging device 1b1 through the flashlight behind collimating mirror and the scanning means respectively and get final product.
Further, the structure of block diagram sketch map of the second embodiment of ophthalmology OCT of the present invention as shown in Figure 4 system, ophthalmology OCT system 1 comprises outside oculi posterior segment OCT imaging system 1a and the anterior ocular segment OCT imaging system 1b, can also comprise the solid optometry 1c of system and iris image pickup optical system 1d, wherein
Admittedly look light source 121, Diopter accommodation device 112, the second lens and ophthalmofundoscope 115 Gu the 1c of optometry system comprises, the second lens are to comprise two lens among Fig. 4, and lens 119 and lens 120 describe for example;
Iris image pickup optical system 1d comprises pickup-light source 124, camera head 122, the 3rd lens 123 and ophthalmofundoscope 115;
Particularly, the light channel structure sketch map of the first embodiment of ophthalmology OCT of the present invention as shown in Figure 5 system, ophthalmology OCT system 1 also comprises light source 101, fiber coupler 102, reference arm 103, lens 104, reflecting mirror 105, detector 106, computer 107, collimating mirror 108, scanning means 109 (can be X-Y scanning direction device etc.), the second dichroic mirror 111, Diopter accommodation device 112, the 3rd dichroic mirror 113, reflecting mirror 114, the light source 124 among reflecting mirror 117, the first dichroic mirrors 118 and the iris image pickup optical system 1d;
Need to prove that among Fig. 3 and Fig. 4 embodiment, oculi posterior segment OCT imaging system 1a can also comprise the modules such as ophthalmofundoscope 115, collimating mirror, scanning means, Diopter accommodation device and reflecting mirror, just complete illustrating not among Fig. 3 and Fig. 4; Anterior ocular segment probe imaging device 1b1 can also comprise optical path switching device 110.Namely, ophthalmology OCT system 1 in the embodiment of the invention contains optical path switching device 110, optical path switching device 110 can belong to oculi posterior segment OCT imaging system 1a, also can belong among the anterior ocular segment OCT imaging system 1b, also can belong to simultaneously oculi posterior segment OCT imaging system 1a and anterior ocular segment OCT imaging system 1b.Particularly, the structure of block diagram sketch map of the 3rd embodiment of ophthalmology OCT of the present invention as shown in Figure 6 system; Oculi posterior segment OCT imaging system 1a can comprise optical path switching device 110, and anterior ocular segment OCT imaging system 1b also comprises optical path switching device 110.
Below, become the oculi posterior segment OCT 1a of system, the solid 1c of optometry system, the 1b of anterior ocular segment OCT system and iris image pickup optical system 1d to be elaborated ophthalmology OCT system decomposition of the present invention:
The light channel structure sketch map of oculi posterior segment OCT system in the ophthalmology OCT of the present invention as shown in Figure 7 system, the second dichroic mirror 111 is between the transmission light path of Diopter accommodation device 112 and lens 119; When ophthalmology OCT system 1 carries out the oculi posterior segment scanning imagery, optical path switching device 110 will receive the light path converting instruction that system sends, adjust the reflected light angle of optical path switching device 110, make incident illumination and upwards reflection vertical with reflected light as being adjusted among Fig. 7, so that send from light source 101, be transformed into the second dichroic mirror 111 through the flashlight behind collimating mirror 108 and the scanning means 109 respectively, the second dichroic mirror 111 reflects described flashlight and enters successively Diopter accommodation device 112 and ophthalmofundoscope 115 (particularly, passed through successively Diopter accommodation device 112, the 3rd dichroic mirror 113, reflecting mirror 114 and ophthalmofundoscope 115), to carry out the oculi posterior segment scanning imagery.
Particularly, the optical path switching device 110 in the ophthalmology OCT system can carry out the conversion of anterior ocular segment scanning imagery according to the instruction that receives, or carries out the conversion of oculi posterior segment scanning imagery; Ophthalmology OCT system in the embodiment of the invention can also set original state for carrying out the oculi posterior segment scanning imagery, when ophthalmology OCT system need to carry out the anterior ocular segment scanning imagery, optical path switching device 110 is just changed according to the instruction that receives, after ophthalmology OCT system finishes the anterior ocular segment scanning imagery, with the original state of automatically adjusting back into row oculi posterior segment scanning imagery, namely be equivalent to optical path switching device 110 and be automatically converted to the state that carries out the oculi posterior segment scanning imagery, and described the first dichroic mirror is withdrawn out light path.
Particularly, comprise the oculi posterior segment probe imaging device 1a1 that is formed by collimating mirror 108, scanning means 109, optical path switching device 110, the second dichroic mirror 111, Diopter accommodation device 112, the 3rd dichroic mirror 113, reflecting mirror 114 and ophthalmofundoscope 115 among the 1a of oculi posterior segment OCT system; Light source 101 comprises the weak coherent light source in the oculi posterior segment OCT imaging optical path, and the light of its output provides light through fiber coupler 102 to oculi posterior segment probe imaging device 1a1 and reference arm 103.Reference arm 103 has known length and by reflecting mirror 105 luminous reflectance is got back in the fiber coupler 102.Oculi posterior segment probe imaging device 1a1 provide light to tested human eye E, the light of returning from the scattering of oculi posterior segment probe imaging device 1a1 and the reflected light of reference arm 103 interfere in fiber coupler 102, interference light is detected device 106 and detects, process through computer 107 again, show at last.
Need to prove that light source 101 output wavelengths include but not limited to be about the near infrared light of 815～865nm.
The light channel structure sketch map of solid optometry system in the ophthalmology OCT of the present invention as shown in Figure 8 system, admittedly after looking the light signal of light source 121 and passing through successively lens 120, lens 119, directly also passed through successively Diopter accommodation device 112 by 111 transmissions of the second dichroic mirror, the 3rd dichroic mirror 113, reflecting mirror 114 and ophthalmofundoscope 115 finally enter human eye E.
Particularly, Gu looking light source 121, consolidating among the 1c of optometry system can be LCD, to show the solid sighting target (inner solid sighting target) that is used for tested human eye E and admittedly looks.After being focused from the light scioptics 120 of LCD, by 111 transmissions of the second dichroic mirror, carry out refraction compensation through Diopter accommodation device 112 after, reflexed to reflecting mirror 114 by the 3rd dichroic mirror 113, finally incide tested human eye E through ophthalmofundoscope 115; Thus, inner solid sighting target is projected to the optical fundus of tested human eye E.Need to prove that LCD is an example, admittedly look light source 121 also can use other solid view apparatus, such as a plurality of LED that are arranged side by side etc.; The solid optometry 1c of system in the embodiment of the invention can change with its inner solid sighting target the solid apparent place of tested eye E, inner solid sighting target can about, move left and right, satisfy the detection of human eye diverse location.
The light channel structure sketch map of anterior ocular segment OCT system in the ophthalmology OCT of the present invention as shown in Figure 9 system, the first dichroic mirror 118 is between the transmission light path of ophthalmofundoscope 115 and Diopter accommodation device 112, particularly, among Fig. 9 the first dichroic mirror 118 between the transmission light path of ophthalmofundoscope 115 and reflecting mirror 114;
Anterior ocular segment probe imaging device 1b1 among the 1b of anterior ocular segment OCT system can be comprised of collimating mirror 108, scanning means 109, optical path switching device 110, lens 116, reflecting mirror 117, the first dichroic mirror 118 and ophthalmofundoscope 115; When ophthalmology OCT system 1 carries out the anterior ocular segment scanning imagery, after optical path switching device 110 receives the light path converting instruction, adjust the reflected light angle of optical path switching device 110, make incident illumination and downwards reflection vertical with reflected light as being adjusted among Fig. 9, so that send from light source 101, after being transformed into the lens 116 of anterior ocular segment probe imaging device 1b1 through the flashlight behind collimating mirror 108 and the scanning means 109 respectively, simultaneously, anterior ocular segment probe imaging device 1b1 receives the driving instruction that ophthalmology OCT system 1 sends, can adjust the angle of the first dichroic mirror 118, so that described flashlight is reflected into into ophthalmofundoscope 115, also the first dichroic mirror 118 can be inserted at a certain angle the place ahead of ophthalmofundoscope 115, namely, the first dichroic mirror 118 is inserted at a certain angle between the transmission light path of ophthalmofundoscope 115 and reflecting mirror 114, so that described flashlight is reflected into into ophthalmofundoscope 115, to carry out the anterior ocular segment scanning imagery.
Need to prove, can distinguish successively through the flashlight behind collimating mirror 108 and the scanning means 109 respectively and arrive the first dichroic mirror 118 through a plurality of lens 116 and reflecting mirror 117, in Fig. 9, lens 116, reflecting mirror 117 have been passed through successively through the flashlight behind collimating mirror 108 and the scanning means 109 respectively, lens 116a and reflecting mirror 117a arrive the first dichroic mirror 118, by the first dichroic mirror 118 flashlight is reflected into into ophthalmofundoscope 115, to carry out the anterior ocular segment scanning imagery.
Also need to prove, in the anterior ocular segment OCT system in the embodiment of the invention by lens 116, reflecting mirror 117, lens 116a has consisted of afocal system, so that the scanning optical path that disperse at scanning means 109 places among the joint probe imaging device 1b1 before eyes can converge at the back focus of ophthalmofundoscope 115, and the parallel OCT that enters still can parallelly pass the back focus of ophthalmofundoscope 115, be the back focus conjugation of scanning means 109 central points and ophthalmofundoscope 115, and light path adopt symmetric design.
The light channel structure sketch map of iris image pickup optical system in the ophthalmology OCT of the present invention as shown in Figure 10 system, the light that pickup-light source 124 among the iris image pickup optical system 1d sends through after the corneal reflex through ophthalmofundoscope 115 after, enter successively lens 123 and camera head 122.
Particularly, pickup-light source 124 comprises that 1124a and 123b (can be the visible light of the 780nm) illumination of sending are mapped to the cornea of tested person's eye E, and reflect at cornea.Reflected light is via ophthalmofundoscope 115, directly enter reflecting mirror 114, and reflecting mirror 114 reflections enter the 3rd dichroic mirror 113, are directly entered lens 123 by 113 transmissions of the 3rd dichroic mirror, are finally photographed by shooting device 122;
Need to prove, the tester uses the lower jaw rest device to make tested eye fixing, make from the tested eye of the solid apparent of the solid sighting target among the solid optometry 1c of system, afterwards, the tester is on one side by observing the display screen of computer 107, the movement by action bars control lower jaw rest device on one side, so that the cornea of tested eye E enters in the camera head 122, and cornea looks like to be presented in the display screen of computer 107.
Ophthalmology OCT system light path structure in the embodiment of the invention includes but not limited to the light channel structure shown in Fig. 3, the light channel structure sketch map of the second embodiment of ophthalmology OCT can also be as shown in Figure 11 of the present invention system, light path can ingehious design, to reduce the number of reflecting mirror, simplifies light path.Particularly:
When ophthalmology OCT system 1 carries out the oculi posterior segment scanning imagery, optical path switching device 110 will be as shown in Figure 11, make incident illumination and upwards reflection vertical with reflected light, so that send from light source 101, be transformed into Diopter accommodation device 112 and ophthalmofundoscope 115 through the flashlight behind collimating mirror 108 and the scanning means 109 respectively, to carry out the oculi posterior segment scanning imagery; Particularly, send from light source 101, be transformed into Diopter accommodation device 112 and the 3rd dichroic mirror 113 through the flashlight behind collimating mirror 108 and the scanning means 109 respectively, reflex to ophthalmofundoscope 115 by the 3rd dichroic mirror 113, to carry out the oculi posterior segment scanning imagery.When ophthalmology OCT system 1 carries out the oculi posterior segment scanning imagery, ophthalmology OCT system 1 withdraws out the first dichroic mirror 118 between the transmission light path of Diopter accommodation device 112 and ophthalmofundoscope 115, for example can the first dichroic mirror 118 levels are horizontal, so that flashlight directly enters ophthalmofundoscope 115 from the 3rd dichroic mirror 113, to carry out the oculi posterior segment scanning imagery;
When ophthalmology OCT system 1 carries out the anterior ocular segment scanning imagery, after optical path switching device 110 receives the light path converting instruction, adjust the reflected light angle of optical path switching device 110, for example be rotated counterclockwise 45 degree by default direction, also optical path switching device 110 can be withdrawn out between the transmission light path of scanning means 109 and lens 116, so that send from light source 101, be transformed into respectively the lens 116 of anterior ocular segment probe imaging device through the flashlight behind collimating mirror 108 and the scanning means 109, simultaneously, anterior ocular segment probe imaging device receives the driving instruction that ophthalmology OCT system 1 sends, the first dichroic mirror 118 is inserted the place ahead of ophthalmofundoscope 115 with predetermined angle, namely, the first dichroic mirror 118 is inserted at a certain angle between the transmission light path of ophthalmofundoscope 115 and the 3rd dichroic mirror 113, so that described flashlight is reflected into into ophthalmofundoscope 115, to carry out the anterior ocular segment scanning imagery.
Embodiment among Figure 11 has reduced the second dichroic mirror 111 and reflecting mirror 114 than the embodiment among Fig. 9, has simplified light path.The embodiment of the invention is not limited to the light channel structure of Fig. 9 or Figure 11, and the light channel structure of Fig. 9 or Figure 11 is preferred embodiment, and the equivalent variations of therefore doing according to claim of the present invention still belongs to the scope that the present invention is contained;
Need to prove, optical path switching device 110 is the completely reflecting mirror of rotatable adjusting, when described ophthalmology OCT system 1 carries out the anterior ocular segment scanning imagery, optical path switching device 110 can be according to the default angle of design rotation of light path after receiving the light path converting instruction, namely carry out the adjusting of position according to the demand of current light channel structure design, for example among Fig. 9 embodiment dextrorotation is turn 90 degrees, to be rotated counterclockwise 45 degree among Figure 11 embodiment, to send from light source 101, be transformed in the described anterior ocular segment probe imaging device through the flashlight behind collimating mirror 108 and the scanning means 109 respectively; The first dichroic mirror 118 inserts between the transmission light path of ophthalmofundoscope 115 and the 3rd dichroic mirror 113 at a certain angle, described flashlight is reflected into into ophthalmofundoscope 115, to carry out the anterior ocular segment scanning imagery.And after finishing the anterior ocular segment scanning imagery, ophthalmology OCT system 1 can be converted to the state that carries out the oculi posterior segment scanning imagery with optical path switching device 110 automatically, namely, for example automatically optical path switching device 110 is rotated counterclockwise 90 degree among Fig. 9 embodiment, automatically optical path switching device 110 is spent along pointer rotation 45 among Figure 11 embodiment, thereby adjust the original state back into row oculi posterior segment scanning imagery, and the first dichroic mirror 118 is withdrawn out light path.
Need to prove, optical path switching device 110 receive after the light path converting instruction that the default angle of design rotation according to light path comprises that the dextrorotation that is not limited among Fig. 9 embodiment turn 90 degrees or Figure 11 embodiment in be rotated counterclockwise 45 degree etc., as long as optical path switching device 110 is finished the conversion of light path according to the default angle of design rotation of light path.
The second dichroic mirror 111 in the embodiment of the invention can make the flashlight that light source 101 sends in the ophthalmology OCT system 1, and (wavelength can be about 800～880nm) reflections, and to looking light (wavelength can be 550nm) transmission from admittedly looking consolidating that light source 121 sends among the solid optometry 1c of system;
The first dichroic mirror 118 can make the flashlight reflection of transmitting among the anterior ocular segment probe imaging device 1b1, and also can reflect looking light from consolidating of looking admittedly among the solid optometry 1c of system light source 121 sends, and can also carry out transmission to the illumination light (wavelength can be about 780nm) of sending from the light source 124 among the iris image pickup optical system 1d;
The 3rd dichroic mirror 113 not only can make the flashlight reflection that light source 101 sends in the ophthalmology OCT system 1, and also can reflect looking light from consolidating of looking admittedly among the solid optometry 1c of system light source 121 sends, and can also carry out transmission to the illumination light of sending from the light source 124 among the iris image pickup optical system 1d;
In the oculi posterior segment OCT imaging system of the embodiment of the invention, oculi posterior segment probe imaging device 1a1 with admittedly look light path and all need Diopter accommodation device 112, thereby admittedly look light path and the shared same Diopter accommodation device 112 of fundus imaging light path; In the anterior ocular segment OCT imaging system, anterior ocular segment probe imaging device 1b1 need not Diopter accommodation device 112, needs Diopter accommodation device 112 and admittedly look light path.
Implement the embodiment of the invention, by optical path switching device is set, when ophthalmology OCT system carries out the anterior ocular segment scanning imagery, to send from light source, be transformed in the described anterior ocular segment probe imaging device through the flashlight behind collimating mirror and the scanning means respectively, to carry out the anterior ocular segment scanning imagery, when having realized that human eye for different visions carries out the anterior ocular segment imaging, both carried out refraction compensation and remained that point of fixation was clear, do not affect again the image quality of anterior ocular segment OCT, solve point of fixation in the prior art regulate can not fine coupling with the OCT image quality problem; And the ophthalmology OCT system structure of the embodiment of the invention is simple, easy to operate, ophthalmology OCT system by the embodiment of the invention, Aplanatic Surface is positioned at the human eye retina during oculi posterior segment OCT imaging, Aplanatic Surface is positioned at cornea during anterior ocular segment OCT imaging, need not to realize the anterior ocular segment imaging by the light path of regulating reference arm; Point of fixation can about move up and down to realize that human eye watches the adjusting of position attentively, watch and survey the different measuring needs at macula lutea or optic nerve, angle, room etc. attentively to satisfy right and left eyes.
The above describes the structure of the ophthalmology OCT system of the embodiment of the invention in detail, and the below describes the ophthalmology OCT formation method of the embodiment of the invention in detail accordingly.
The schematic flow sheet of the ophthalmology OCT formation method of the embodiment of the invention as shown in Figure 12 comprises
Step S1201: when carrying out the anterior ocular segment scanning imagery, optical path switching device is according to the light path converting instruction that receives, to send from light source, be transformed into through the flashlight behind collimating mirror and the scanning means respectively and contain in first lens, the first dichroic mirror and the ophthalmoscopic anterior ocular segment probe imaging device, described anterior ocular segment probe imaging device drives described the first dichroic mirror described flashlight reflection is entered described ophthalmofundoscope, to carry out the anterior ocular segment scanning imagery;
Step S1202: the original state of ophthalmology OCT system is for carrying out the oculi posterior segment scanning imagery, after described ophthalmology OCT system finishes the anterior ocular segment scanning imagery, with the original state of adjusting back into row oculi posterior segment scanning imagery, described the first dichroic mirror withdrawn out light path.
Particularly, optical path switching device includes but not limited to the completely reflecting mirror of rotatable adjusting, as long as after realizing receiving the light path converting instruction, will send from light source, pass through respectively flashlight behind collimating mirror and the scanning means and be transformed into anterior ocular segment and pop one's head in and get final product in the imaging device.
Again further, the ophthalmology OCT formation method of the embodiment of the invention also comprises: when carrying out the oculi posterior segment scanning imagery, optical path switching device will send from light source, be transformed into the second dichroic mirror through the flashlight behind collimating mirror and the scanning means respectively, described the second dichroic mirror reflects described flashlight and enters successively Diopter accommodation device and the described ophthalmofundoscope of solid optometry system, to carry out the oculi posterior segment scanning imagery; Perhaps
When carrying out the oculi posterior segment scanning imagery, optical path switching device will send from light source, directly be transformed into successively respectively Diopter accommodation device and the described ophthalmofundoscope of solid optometry system through the flashlight behind collimating mirror and the scanning means, carrying out the oculi posterior segment scanning imagery.
The flow process of the ophthalmology OCT formation method of the embodiment of the invention can be corresponding to above-mentioned detailed description to ophthalmology OCT system.
In sum, by optical path switching device is set, when ophthalmology OCT system carries out the anterior ocular segment scanning imagery, to send from light source, be transformed in the described anterior ocular segment probe imaging device through the flashlight behind collimating mirror and the scanning means respectively, to carry out the anterior ocular segment scanning imagery, when having realized that human eye for different visions carries out the anterior ocular segment imaging, both carried out refraction compensation and remained that point of fixation was clear, do not affect again the image quality of anterior ocular segment OCT, solve point of fixation in the prior art regulate can not fine coupling with the OCT image quality problem; And the ophthalmology OCT system structure of the embodiment of the invention is simple, easy to operate, ophthalmology OCT system by the embodiment of the invention, Aplanatic Surface is positioned at the human eye retina during oculi posterior segment OCT imaging, Aplanatic Surface is positioned at cornea during anterior ocular segment OCT imaging, need not to realize the anterior ocular segment imaging by the light path of regulating reference arm; Point of fixation can about move up and down to realize that human eye watches the adjusting of position attentively, watch and survey the different measuring needs at macula lutea or optic nerve, angle, room etc. attentively to satisfy right and left eyes.
One of ordinary skill in the art will appreciate that all or part of flow process that realizes in above-described embodiment method, to come the relevant hardware of instruction to finish by computer program, described program can be stored in the computer read/write memory medium, this program can comprise the flow process such as the embodiment of above-mentioned each side method when carrying out.Wherein, described storage medium can be magnetic disc, CD, read-only store-memory body (Read-Only Memory, ROM) or store-memory body (Random Access Memory, RAM) etc. at random.
Above disclosed is a kind of preferred embodiment of the present invention only, certainly can not limit with this interest field of the present invention, and the equivalent variations of therefore doing according to claim of the present invention still belongs to the scope that the present invention is contained.
Claims (10)
1. ophthalmology OCT system, it is characterized in that, comprise oculi posterior segment OCT imaging system and anterior ocular segment OCT imaging system, described oculi posterior segment OCT imaging system comprises optical path switching device, described anterior ocular segment OCT imaging system comprises anterior ocular segment probe imaging device, described anterior ocular segment probe imaging device contains ophthalmofundoscope, the first dichroic mirror and first lens, wherein
When described ophthalmology OCT system carries out the anterior ocular segment scanning imagery, after described optical path switching device receives the light path converting instruction, will send from light source, be transformed in the described anterior ocular segment probe imaging device through the flashlight behind collimating mirror and the scanning means respectively;
Described anterior ocular segment probe imaging device drives described the first dichroic mirror described flashlight reflection is entered described ophthalmofundoscope, to carry out the anterior ocular segment scanning imagery.
2. ophthalmology OCT as claimed in claim 1 system is characterized in that, also comprises solid optometry system and iris image pickup optical system, wherein
Described solid optometry system comprises looks light source, Diopter accommodation device, the second lens and described ophthalmofundoscope admittedly;
Described iris image pickup optical system comprises pickup-light source, camera head, the 3rd lens and described ophthalmofundoscope.
3. ophthalmology OCT as claimed in claim 2 system, it is characterized in that, the original state of ophthalmology OCT system is for carrying out the oculi posterior segment scanning imagery, after described ophthalmology OCT system finishes the anterior ocular segment scanning imagery, with the original state of adjusting back into row oculi posterior segment scanning imagery, described the first dichroic mirror is withdrawn out light path.
4. ophthalmology OCT as claimed in claim 3 system is characterized in that described oculi posterior segment OCT imaging system also comprises the second dichroic mirror, and described the second dichroic mirror is between the transmission light path of described Diopter accommodation device and described the second lens; Wherein
When described ophthalmology OCT system carries out the oculi posterior segment scanning imagery, described optical path switching device will send from light source, be transformed into described the second dichroic mirror through the flashlight behind collimating mirror and the scanning means respectively, described the second dichroic mirror reflects described flashlight and enters successively described Diopter accommodation device and described ophthalmofundoscope, to carry out the oculi posterior segment scanning imagery; Perhaps
Described optical path switching device will send from light source, directly be transformed into successively described Diopter accommodation device and described ophthalmofundoscope through the flashlight behind collimating mirror and the scanning means respectively, carrying out the oculi posterior segment scanning imagery.
5. ophthalmology OCT as claimed in claim 4 system is characterized in that, the described light signal of admittedly looking light source is through behind described the second lens, directly by described the second dichroic mirror transmission and enter successively described Diopter accommodation device and described ophthalmofundoscope.
6. ophthalmology OCT as claimed in claim 3 system is characterized in that described optical path switching device is the completely reflecting mirror of rotatable adjusting;
When described ophthalmology OCT system carries out the anterior ocular segment scanning imagery, described optical path switching device rotates default angle according to the design of light path after receiving the light path converting instruction, to send from light source, be transformed in the described anterior ocular segment probe imaging device through the flashlight behind collimating mirror and the scanning means respectively; Described anterior ocular segment probe imaging device drives described the first dichroic mirror and inserts light path according to default angle, described flashlight reflection is entered described ophthalmofundoscope, to carry out the anterior ocular segment scanning imagery.
7. ophthalmology OCT as claimed in claim 3 system is characterized in that, described solid optometry system also comprises the 3rd dichroic mirror, and described the 3rd dichroic mirror is between the transmission light path of described ophthalmofundoscope and described Diopter accommodation device; Wherein
The described light signal of admittedly looking light source is through behind the described Diopter accommodation device, by described the 3rd dichroic mirror reflects and enter described ophthalmofundoscope.
8. ophthalmology OCT as claimed in claim 7 system, it is characterized in that, the light that the pickup-light source of described iris image pickup optical system sends through described ophthalmofundoscope, is directly also entered described the 3rd lens and described camera head by described the 3rd dichroic mirror transmission successively after corneal reflex.
9. an ophthalmology OCT formation method is characterized in that, comprising:
When carrying out the anterior ocular segment scanning imagery, optical path switching device is according to the light path converting instruction that receives, to send from light source, be transformed in the anterior ocular segment probe imaging device that contains ophthalmofundoscope, the first dichroic mirror and first lens through the flashlight behind collimating mirror and the scanning means respectively, described anterior ocular segment probe imaging device drives described the first dichroic mirror described flashlight reflection is entered described ophthalmofundoscope, to carry out the anterior ocular segment scanning imagery;
The original state of ophthalmology OCT system is for carrying out the oculi posterior segment scanning imagery, after described ophthalmology OCT system finishes the anterior ocular segment scanning imagery, with the original state of adjusting back into row oculi posterior segment scanning imagery, described the first dichroic mirror withdrawn out light path.
10. ophthalmology OCT formation method as claimed in claim 9, it is characterized in that, when carrying out the oculi posterior segment scanning imagery, optical path switching device will send from light source, be transformed into the second dichroic mirror through the flashlight behind collimating mirror and the scanning means respectively, described the second dichroic mirror reflects described flashlight and enters successively Diopter accommodation device and the described ophthalmofundoscope of solid optometry system, to carry out the oculi posterior segment scanning imagery; Perhaps
When carrying out the oculi posterior segment scanning imagery, optical path switching device will send from light source, directly be transformed into successively respectively Diopter accommodation device and the described ophthalmofundoscope of solid optometry system through the flashlight behind collimating mirror and the scanning means, carrying out the oculi posterior segment scanning imagery.
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