WO2012141502A3 - Controlled release type tablet containing aceclofenac - Google Patents

Controlled release type tablet containing aceclofenac Download PDF

Info

Publication number
WO2012141502A3
WO2012141502A3 PCT/KR2012/002769 KR2012002769W WO2012141502A3 WO 2012141502 A3 WO2012141502 A3 WO 2012141502A3 KR 2012002769 W KR2012002769 W KR 2012002769W WO 2012141502 A3 WO2012141502 A3 WO 2012141502A3
Authority
WO
WIPO (PCT)
Prior art keywords
controlled release
release type
type tablet
tablet containing
tablet
Prior art date
Application number
PCT/KR2012/002769
Other languages
French (fr)
Korean (ko)
Other versions
WO2012141502A2 (en
Inventor
어진
한창균
정현근
김양중
김종걸
이정화
하남성
Original Assignee
안국약품 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 안국약품 주식회사 filed Critical 안국약품 주식회사
Priority to MX2013011891A priority Critical patent/MX346466B/en
Priority to BR112013026473-0A priority patent/BR112013026473B1/en
Publication of WO2012141502A2 publication Critical patent/WO2012141502A2/en
Publication of WO2012141502A3 publication Critical patent/WO2012141502A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention relates to a controlled release type tablet containing aceclofenac. Particularly, the tablet has a multi-layer structure including a fast releasing layer and a slow releasing layer adjacent to each other. The slow releasing layer includes hydrophilic polymer, hypromellose and polyethylene oxide as slow releasing materials. While the tablet according to the present invention has an even smaller size than that of a conventional controlled release type tablet, it is designed for possible once-a-day dosage.
PCT/KR2012/002769 2011-04-13 2012-04-12 Controlled release type tablet containing aceclofenac WO2012141502A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MX2013011891A MX346466B (en) 2011-04-13 2012-04-12 Controlled release type tablet containing aceclofenac.
BR112013026473-0A BR112013026473B1 (en) 2011-04-13 2012-04-12 TABLET OF CONTROLLED RELEASE TYPE CONTAINING ACCECLOPENAC

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0034022 2011-04-13
KR1020110034022A KR101310099B1 (en) 2011-04-13 2011-04-13 Controlled-release tablet containing aceclofenac

Publications (2)

Publication Number Publication Date
WO2012141502A2 WO2012141502A2 (en) 2012-10-18
WO2012141502A3 true WO2012141502A3 (en) 2013-01-03

Family

ID=47009839

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/002769 WO2012141502A2 (en) 2011-04-13 2012-04-12 Controlled release type tablet containing aceclofenac

Country Status (4)

Country Link
KR (1) KR101310099B1 (en)
BR (1) BR112013026473B1 (en)
MX (1) MX346466B (en)
WO (1) WO2012141502A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102236650B1 (en) * 2019-04-16 2021-04-07 한국유나이티드제약 주식회사 Pharmaceutical Composition Comprising Aceclofenac and Method of Preparing Thereof
KR102426727B1 (en) 2020-04-17 2022-07-28 성균관대학교산학협력단 oral drug delivery system controlling release rate AND manufacturing method for oral drug delivery system controlling release rate

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6599529B1 (en) * 1997-09-11 2003-07-29 Nycomed Danmark A/S Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (NSAIDs)
KR20040077244A (en) * 2003-02-28 2004-09-04 한국유나이티드제약 주식회사 Controlled release pellets for oral and it's manufacturing process
JP2005232185A (en) * 2003-03-06 2005-09-02 Astellas Pharma Inc Medicinal composition for regulating release and process for producing the same
US20070092573A1 (en) * 2005-10-24 2007-04-26 Laxminarayan Joshi Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist
KR20090022612A (en) * 2007-08-31 2009-03-04 주식회사 드림파마 A novel composition for sustained release-aceclofenac formulation and a method for preparing the same
KR20100064015A (en) * 2008-12-04 2010-06-14 한국유나이티드제약 주식회사 Controlled-release aceclofenac containing oral drug preparations and it's manufacturing process

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6599529B1 (en) * 1997-09-11 2003-07-29 Nycomed Danmark A/S Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (NSAIDs)
KR20040077244A (en) * 2003-02-28 2004-09-04 한국유나이티드제약 주식회사 Controlled release pellets for oral and it's manufacturing process
JP2005232185A (en) * 2003-03-06 2005-09-02 Astellas Pharma Inc Medicinal composition for regulating release and process for producing the same
US20070092573A1 (en) * 2005-10-24 2007-04-26 Laxminarayan Joshi Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist
KR20090022612A (en) * 2007-08-31 2009-03-04 주식회사 드림파마 A novel composition for sustained release-aceclofenac formulation and a method for preparing the same
KR20100064015A (en) * 2008-12-04 2010-06-14 한국유나이티드제약 주식회사 Controlled-release aceclofenac containing oral drug preparations and it's manufacturing process

Also Published As

Publication number Publication date
BR112013026473A2 (en) 2016-12-20
KR101310099B1 (en) 2013-09-23
BR112013026473A8 (en) 2018-01-30
KR20120116545A (en) 2012-10-23
MX2013011891A (en) 2014-03-31
BR112013026473B1 (en) 2021-10-13
WO2012141502A2 (en) 2012-10-18
MX346466B (en) 2017-03-22

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