WO2012140713A1 - Support et dispositif de mesure de lumière utilisant ledit support - Google Patents

Support et dispositif de mesure de lumière utilisant ledit support Download PDF

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Publication number
WO2012140713A1
WO2012140713A1 PCT/JP2011/058985 JP2011058985W WO2012140713A1 WO 2012140713 A1 WO2012140713 A1 WO 2012140713A1 JP 2011058985 W JP2011058985 W JP 2011058985W WO 2012140713 A1 WO2012140713 A1 WO 2012140713A1
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WO
WIPO (PCT)
Prior art keywords
light
probe
holder
probe mounting
mounting portion
Prior art date
Application number
PCT/JP2011/058985
Other languages
English (en)
Japanese (ja)
Inventor
晴英 宇田川
井上 芳浩
孝司 網田
理 河野
石川 亮宏
善紀 増田
Original Assignee
株式会社島津製作所
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社島津製作所 filed Critical 株式会社島津製作所
Priority to JP2013509676A priority Critical patent/JP5561429B2/ja
Priority to PCT/JP2011/058985 priority patent/WO2012140713A1/fr
Publication of WO2012140713A1 publication Critical patent/WO2012140713A1/fr

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14553Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for cerebral tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6814Head
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3563Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solids; Preparation of samples therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04Arrangements of multiple sensors of the same type
    • A61B2562/046Arrangements of multiple sensors of the same type in a matrix array
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026Measuring blood flow
    • A61B5/0261Measuring blood flow using optical means, e.g. infrared light

Definitions

  • the present invention relates to a holder and an optical measurement device using the holder.
  • a plurality of light transmission points for irradiating light to a living body and a plurality of light receiving points for receiving light emitted from the living body are determined for each set of one light transmission point and one light receiving point.
  • the present invention relates to a holder for measuring in-vivo internal information about the channels of the channel and an optical measurement device using the holder.
  • an optical brain functional imaging apparatus (optical measurement apparatus) that measures light simply and non-invasively has been developed.
  • three different types of wavelengths ⁇ 1 , ⁇ 2 , and ⁇ 3 (for example, 780 nm, 805 nm, and 830 nm) are close by a light transmission probe disposed on the head surface of the subject.
  • Infrared light is irradiated onto the brain, and the intensity (received light amount information) A of the near-infrared light of each wavelength ⁇ 1 , ⁇ 2 , ⁇ 3 emitted from the brain by a light receiving probe arranged on the head surface.
  • concentration / optical path length product of total hemoglobin ([oxyHb] + [deoxyHb]) is calculated from the concentration / optical path length product [oxyHb] of oxyhemoglobin and the deoxyhemoglobin concentration / optical path length product [deoxyHb]. Yes.
  • a ( ⁇ 1 ) E O ( ⁇ 1 ) ⁇ [oxyHb] + E d ( ⁇ 1 ) ⁇ [deoxyHb] (1)
  • a ( ⁇ 2 ) E O ( ⁇ 2 ) ⁇ [oxyHb] + E d ( ⁇ 2 ) ⁇ [deoxyHb] (2)
  • a ( ⁇ 3 ) E O ( ⁇ 3 ) ⁇ [oxyHb] + E d ( ⁇ 3 ) ⁇ [deoxyHb] (3)
  • E O ( ⁇ m) is an absorbance coefficient of oxyhemoglobin in light having a wavelength ⁇ m
  • E d ( ⁇ m) is an absorbance coefficient of deoxyhemoglobin in light having a wavelength ⁇ m.
  • FIG.5 (a) is sectional drawing which shows the relationship between a pair of light transmission probe and light reception probe, and a measurement site
  • FIG.5 (b) is a top view of Fig.5 (a).
  • the light transmitting probe 12 is pressed against the light transmitting point T on the subject's head surface, and the light receiving probe 13 is pressed against the light receiving point R on the subject's head surface. Then, light is emitted from the light transmitting probe 12 and light emitted from the head surface is incident on the light receiving probe 13.
  • FIG. 6 is a block diagram showing an example of a schematic configuration of a conventional near-infrared spectrometer. For ease of viewing, several light transmitting optical fibers and several light receiving optical fibers are omitted.
  • the near-infrared spectrometer 201 has a rectangular parallelepiped casing 11.
  • a light source 2 that emits light
  • a light source driving mechanism 4 that drives the light source 2
  • a light detector 3 that detects light
  • an A / D (A / D converter) 5 an A / D (A / D converter) 5
  • the light receiving control unit 21, the analysis control unit 22, and the memory 23 are provided, and 64 light transmission probes 12, 64 light reception probes 13, and 64 light transmission probes are provided outside the housing 11.
  • the optical fiber 14 for light, the 64 optical fibers 15 for light reception, the display apparatus 26 which has the monitor screen 26a, etc., and the keyboard (input device) 27 are provided.
  • the light source drive mechanism 4 drives the light source 2 by a drive signal input from the light transmission / reception controller 21.
  • the light source 2 is, for example, a semiconductor laser LD1, LD2, or LD3 that can emit near-infrared light having three different wavelengths ⁇ 1 , ⁇ 2 , and ⁇ 3 .
  • the photodetector 3 transmits and receives light reception signals (light reception amount information) A ( ⁇ 1 ), A ( ⁇ 2 ), and A ( ⁇ 3 ) via A / D 5 by detecting near infrared light respectively.
  • a photomultiplier tube For example, a photomultiplier tube.
  • the light transmitting optical fiber 14 and the light receiving optical fiber 15 are tubular having a diameter of 2 mm and a length of 2 m to 10 m, can transmit near infrared light in the axial direction, and receive near infrared light incident from one end. Light passes through the inside and exits from the other end, or near-infrared light incident from the other end passes through the inside and exits from one end.
  • One light transmission optical fiber 14 has both end portions so that one light transmission probe 12 and one semiconductor laser LD1, LD2, LD3 of the light source 2 are separated by a set length (2 m to 10 m). Connected to.
  • One light receiving optical fiber 15 connects one light receiving probe 13 and one photomultiplier tube of the photodetector 3 to both ends so as to be separated by a set length (2 m to 10 m). ing.
  • FIG. 7 is a plan view showing an example of the holder 30 into which 64 light transmitting probes and 64 light receiving probes are inserted.
  • the light transmitting probes 12 T1 to 12 T64 and the light receiving probes 13 R1 to 13 R64 are arranged so as to alternate between 16 in the vertical direction and 16 in the horizontal direction.
  • the light receiving amount information A ( ⁇ 1 ), A ( ⁇ 2 ), and A ( ⁇ 3 ) that makes the probe interval between the light transmitting probe 12 and the light receiving probe 13 constant and a specific depth from the head surface is obtained.
  • a channel with a channel of 30 mm is used.
  • the position at a depth of 15 mm to 20 mm from the head surface substantially corresponds to the brain surface region, and the received light amount information A ( ⁇ 1 ), A ( ⁇ 2 ), A ( ⁇ 3 ) related to the brain activity is obtained. .
  • one light receiving probe 13 irradiates from a plurality of light transmitting probes 12.
  • the timing of irradiating light from the light transmitting probe 12 and the timing of receiving light by the light receiving probe 13 so that only the light irradiated from one light transmitting probe 12 is received without simultaneously receiving the received light. Need to be adjusted.
  • the memory 23 stores a control table indicating the timing of emitting light by the light source 2 and the timing of detecting light by the photodetector 3.
  • the light transmission / reception control unit 21 having such a control table stored in the memory 23 outputs a drive signal for transmitting light to one light transmission probe 12 to the light source drive mechanism 4 at a predetermined time.
  • a light reception signal (light reception amount information) received by the light reception probe 13 is detected by the photodetector 3.
  • a total of 232 (S1 to S232) received light amount information A ( ⁇ 1 ), A ( ⁇ 2 ), A ( ⁇ 3 ) is collected.
  • the analysis control unit 22 uses relational expressions (1), (2), and (3) based on a total of 232 received light amount information A ( ⁇ 1 ), A ( ⁇ 2 ), and A ( ⁇ 3 ).
  • FIG. 10 is a plan view showing an example of a comb-shaped holder.
  • the holder 60 includes one straight basic portion 62 and five straight branch portions 61. According to such a holder 60, even one subject can mount the holder 60 on his / her own head.
  • a probe mounting portion 61 a for inserting a cylindrical light transmission probe (for example, a diameter of 5 mm) or a cylindrical light reception probe (for example, a diameter of 5 mm) is provided at the tip of the branch portion 61. Therefore, even if the hair is scraped off at the tip of the branch portion 61, the scraped hair may enter the periphery of the probe mounting portion 61a.
  • the present inventors have studied a method for preventing hair from entering the vicinity of the probe mounting portion. Therefore, it has been found that a probe mounting portion is formed at the tip of the branch portion.
  • the holder of the present invention has at least two probe mounting portions, and a light transmitting probe that irradiates light from the tip or a light receiving probe that receives light from the tip is inserted into the probe mounting portion,
  • a holder to be attached to the examiner's head comprising: a linear trunk extending in the first direction; and at least two linear branches extending in a second direction different from the first direction.
  • the probe mounting part is formed at the tip of the branch part.
  • first direction and the “second direction” are arbitrary directions determined in advance by a designer of the holder, and the first direction and the second direction are preferably perpendicular to the upper side. Furthermore, the first direction and the second direction are preferably perpendicular to each other.
  • the second direction is a front-rear direction or the like that facilitates insertion of the holder while scraping the hair.
  • the holder of the present invention includes a linear trunk extending in the first direction and at least two linear branches extending in the second direction. That is, the holder has a comb shape. And the probe mounting part is formed in the front-end
  • the holder of the present invention even one subject can easily attach the holder to his / her head in a short time.
  • the probe mounting part has a through hole into which the light transmitting probe or the light receiving probe is inserted, and a lower end part of the probe mounting part protrudes from a lower surface of the branch part. I have to.
  • the lower end portion of the probe mounting portion has an annular shape when viewed from below.
  • the holder of the present invention includes a light shielding cloth having a hole formed at a position corresponding to the probe mounting portion, and the light shielding cloth is attached so as to penetrate the probe mounting portion into the hole. According to the holder of the present invention, external light can be shielded even with a comb-shaped holder.
  • the holder of the present invention includes a fixing member having an insertion portion at both ends and a connecting portion for connecting the insertion portions at both ends at a set distance, and the probe mounting portion is inserted into each insertion portion. Through holes are respectively opened, and the fixing member is attached so as to penetrate the probe mounting portion through the through holes.
  • the “set distance” is an arbitrary distance determined in advance according to the depth of the position of the received light amount information to be obtained. For example, the received light amount information related to the brain activity is obtained. In such a case, it becomes 30 mm or the like.
  • the optical measurement device of the present invention includes a holder as described above, a light transmission probe that irradiates light to the subject, a light reception probe that receives light emitted from the subject, and the light transmission.
  • a control unit that obtains measurement data related to the brain activity of the subject by controlling the probe and the light receiving probe is provided.
  • the figure of the holder to which the light shielding cloth was attached.
  • the figure of the holder to which the fixing member was attached.
  • FIG. 1 is a block diagram showing a schematic configuration of an optical measurement apparatus according to an embodiment of the present invention.
  • 2 to 4 are views showing an example of the holder.
  • the same reference numerals are assigned to the same components as those of the near-infrared spectrometer 201.
  • the optical measuring device 1 has a rectangular parallelepiped housing 11. Inside the housing 11, a light source 2 that emits light, a light source driving mechanism 4 that drives the light source 2, a light detector 3 that detects light, an A / D 5, a light transmission / reception control unit 21, An analysis control unit 22 and a memory 23 are provided, and 64 light-transmitting probes 12, 64 light-receiving probes 13, and 64 light-transmitting optical fibers 14 are provided outside the housing 11. It includes 64 light receiving optical fibers 15, a display device 26 having a monitor screen 26 a and the like, and a keyboard (input device) 27.
  • FIG. 2 is a plan view of the holder
  • FIG. 3 is a perspective view of the holder shown in FIG.
  • the holder 160 includes a linear trunk portion 162 and eight linear branch portions 161.
  • the trunk portion 162 extends in the X direction (first direction) when viewed from the front, and has an arc shape when viewed from above.
  • the width is 15 mm and the thickness is 2 mm.
  • the first left side branch portion 161a extends from the left end portion of the trunk portion 162 in the Y direction (second direction) at an angle of 45 ° with the X direction, and has a width of 15 mm, a thickness of 2 mm, and a length of 50 mm, for example. ing. Furthermore, a cylindrical probe mounting portion 171a having a circular (for example, a diameter of 5 mm) through-hole in a plan view is formed at the tip of the first left branch 161a. In addition, the lower end part of the probe mounting part 171a protrudes from the lower surface of the 1st left side branch part 161a.
  • the second left branch 161b extends in a Y direction (second direction) at an angle of 60 ° with respect to the X direction from a position closer to the center of 50 mm from the left end of the trunk portion 162, and has a width of 15 mm and a thickness, for example. It is 2 mm and length is 70 mm. Further, a cylindrical probe mounting portion 171b having a circular (for example, diameter of 5 mm) through-hole in a plan view is formed at the tip of the second left side branch portion 161b. The lower end portion of the probe mounting portion 171b protrudes from the lower surface of the second left side branch portion 161b.
  • the third left branch 161c extends in the Y direction (second direction) at an angle of 75 ° with respect to the X direction from a position closer to the center of 70 mm from the left end of the trunk 162, and has a width of 15 mm and a thickness, for example. It is 2 mm and length is 85 mm. Further, a cylindrical probe mounting portion 171c having a circular (for example, diameter of 5 mm) through hole in a plan view is formed at the tip of the third left side branch portion 161c. In addition, the lower end part of the probe mounting part 171c protrudes from the lower surface of the third left side branch part 161c.
  • the central branch portion 161i extends from the central portion of the trunk portion 162 in the Y direction (second direction) at an angle of 90 ° with the X direction, and has a width of 15 mm, a thickness of 2 mm, and a length of 60 mm, for example. .
  • the fourth left branch 161d extends from the upper end of the central branch 161i in the Y direction (second direction) at an angle of 45 ° with the X direction.
  • the width is 15 mm
  • the thickness is 2 mm
  • the length is 70 mm. It has become.
  • a cylindrical probe mounting portion 171d having a circular (for example, diameter of 5 mm) through hole in a plan view is formed at the tip of the fourth left side branch portion 161d.
  • the lower end portion of the probe mounting portion 171d protrudes from the lower surface of the fourth left side branch portion 161d.
  • the probe mounting portion 171a of the first left branch portion 161a, the probe mounting portion 171b of the second left branch portion 161b, the probe mounting portion 171c of the third left branch portion 161c, and the fourth left branch portion A first parallelogram having a side of 31.5 mm is formed with the probe mounting portion 171d of 161d.
  • the right half of the holder 160 has the same structure as the left half of the holder 160 described above, and the probe mounting portion 171e of the first right branch 161e and the probe mounting portion 171f of the second right branch 161f.
  • a second parallelogram having one side of 31.5 mm is formed by the probe mounting portion 171g of the third right branch 161g and the probe mounting portion 171h of the fourth right branch 161h.
  • the light transmitting probe 12 has a cylindrical shape (for example, a diameter of 5 mm) that can be fixed to the probe mounting portions 171a to 171h.
  • a light transmission optical fiber 14 (for example, 2 mm in diameter) connected to the light source 2 is fixed inside the light transmission probe 12 via a spring or the like, and light is transmitted from the tip of the light transmission optical fiber 14. Will be irradiated.
  • the light receiving probe 13 has the same structure as the light transmitting probe 12, and has a cylindrical shape (for example, 5 mm in diameter) that can be fixed to the probe mounting portions 171a to 171h.
  • a light receiving optical fiber 15 (for example, 2 mm in diameter) connected to the photodetector 3 is fixed inside the light receiving probe 13 via a spring or the like, and light is transmitted from the tip of the light receiving optical fiber 15. It is designed to receive light.
  • FIG. 4A is a cross-sectional view of a part of the first left branch 161a of the holder 160 to which the light receiving probe 13 is attached
  • FIG. 4B is a holder shown in FIG.
  • FIG. 4C is a sectional view of a part of the first left branch 161a of the holder 160 with the light receiving probe 13 removed.
  • the light receiving probe 13 can be inserted and fixed inside the circular through hole formed in the probe mounting portion 171a. If the light transmitting probes 12 T1 to 12 T4 and the light receiving probes 13 R1 to 13 R4 are inserted into the probe mounting portions 171 having the corresponding numbers as described above, a total of eight probes are obtained in plan view as shown in FIG.
  • the received light amount information A ( ⁇ 1 ), A ( ⁇ 2 ), A ( ⁇ 3 ) in (S1 to S8) can be collected.
  • the material constituting the basic part 162, the branch part 161, and the probe mounting part 171 is not particularly limited, and examples thereof include polypropylene, polyvinyl chloride, polyacetal, and metal.
  • a black light shielding cloth may be attached to the holder 160 so that external light does not enter the light receiving probe 13.
  • 8A is a plan view of the holder 160 to which the two light shielding cloths 81 and 82 are attached
  • FIG. 8B is a cross-sectional view of a part of the holder 160 to which the light shielding cloth 81 is attached. is there.
  • the light shielding cloth 81 has a parallelogram shape with a thickness of 2 mm, and four holes 81 a corresponding to the four probe mounting portions 171 are formed in the light shielding cloth 81.
  • Such a light shielding cloth 81 is attached to the lower surface of the holder 160 so that the four probe mounting portions 171 pass through the four holes 81a.
  • the light shielding cloth 82 has a similar structure.
  • FIG. 9A is a plan view of the holder 160 to which the eight fixing members 90 are attached
  • FIG. 9B is a cross-sectional view of a part of the holder 160 to which the fixing members 90 are attached.
  • the fixing member 90 is a plate-shaped body having a single letter shape, and the fixing member 90 has annular insertion portions at both ends and connecting portions that connect the insertion portions at both ends with a set distance. In the center of each insertion portion, a circular through hole for inserting the probe mounting portion 171 is opened.
  • the connecting portion has a width of 10 mm and a thickness of 0.1 mm, and is formed such that the distance between the center of the through hole and the center of the through hole is a set distance of 31.5 mm. Only flexible. That is, the insertion portions at both ends are always held at the channel length X (30 mm). And it attaches to the lower surface of the holder 160 so that two probe mounting parts 171 may be penetrated by two connection parts.
  • the fixing member 90 and the light shielding cloth 82 are formed thin, and even if the fixing member 90 and the light shielding cloth 82 are attached, the lower end of the probe mounting portion 171 protrudes from the lower surface of the fixing member 90 and the light shielding cloth 82. It is like that.
  • the subject places the light-transmitting probes 12 T1 to 12 T4 and the light-receiving probes 13 R1 to 13 R4 in a predetermined arrangement in the through-holes of the probe mounting portion 171 of the holder 160. Insert with.
  • the subject wears the light shielding cloths 81 and 82 and the fixing member 90 on the lower surface of the holder 160.
  • the subject places the holder 160 on the head from the front of the head toward the rear of the head so as to insert the hair while scraping the hair with the probe mounting portion 171.
  • the optical measurement system 1 of the present invention even one subject can easily attach the holder 160 to his / her head in a short time.
  • the holder 160 is mounted on the head from the front of the head toward the rear of the head. It is good also as a structure which mounts
  • the holder 160 is configured to attach the four light transmitting probes 12 T1 to 12 T4 and the four light receiving probes 13 R1 to 13 R4. The light transmitting probe and eight light receiving probes may be attached, or two light transmitting probes and two light receiving probes may be attached to the holder.
  • the present invention can be used for an optical measurement device or the like that irradiates light inside a living body to acquire internal information.
  • optical measuring device 11 housing 12: light transmitting probe 13: light receiving probe 14: light transmitting optical fiber 15: light receiving optical fiber 22: analysis control unit 26: display device 27: keyboard (input device) 160: Holder 161: Branch part 162: Main part 171: Probe mounting part

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  • Life Sciences & Earth Sciences (AREA)
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  • Spectroscopy & Molecular Physics (AREA)
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  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
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  • Optics & Photonics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

L'invention porte sur un support (160), qui a au moins deux unités de montage de sonde (171). Des sondes d'émission de lumière (12) qui rayonnent une lumière à partir de la pointe, ou des sondes de réception de lumière (13), qui reçoivent une lumière à partir de la pointe, sont insérées dans les unités de montage de sonde (171), et le support (160) est monté sur la tête du patient. Ce support comporte une unité de tronc linéaire (162) s'étendant dans une première direction, et au moins deux ramifications linéaires (161) s'étendant dans une seconde direction différente de la première direction, et les unités de montage de sonde (171) sont formées à l'extrémité des ramifications (161).
PCT/JP2011/058985 2011-04-11 2011-04-11 Support et dispositif de mesure de lumière utilisant ledit support WO2012140713A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2013509676A JP5561429B2 (ja) 2011-04-11 2011-04-11 ホルダ及びそれを用いた光計測装置
PCT/JP2011/058985 WO2012140713A1 (fr) 2011-04-11 2011-04-11 Support et dispositif de mesure de lumière utilisant ledit support

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2011/058985 WO2012140713A1 (fr) 2011-04-11 2011-04-11 Support et dispositif de mesure de lumière utilisant ledit support

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WO2012140713A1 true WO2012140713A1 (fr) 2012-10-18

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WO (1) WO2012140713A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001286449A (ja) * 2000-04-10 2001-10-16 Hitachi Medical Corp プローブ装置
JP2007111407A (ja) * 2005-10-24 2007-05-10 Shimadzu Corp 光生体イメージング装置のマルチプローブホルダー
JP2007236963A (ja) * 2007-04-25 2007-09-20 Hitachi Medical Corp プローブ装置
JP2009077841A (ja) * 2007-09-26 2009-04-16 Shimadzu Corp ホルダ及びこれに用いる光生体測定装置
JP2010115252A (ja) * 2008-11-11 2010-05-27 Shimadzu Corp ホルダー
JP2010188155A (ja) * 2010-04-22 2010-09-02 Hitachi Ltd 生体光計測装置およびそれに用いる被検体装着具

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080027345A1 (en) * 2004-06-25 2008-01-31 Olympus Corporation Electrode Apparatus For Detecting Brain Waves And Package
US10307062B2 (en) * 2010-03-18 2019-06-04 Shimadzu Corporation Holder and light measuring device using same
CN103096813B (zh) * 2010-07-16 2015-01-07 株式会社岛津制作所 支架以及使用该支架的光测量装置

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001286449A (ja) * 2000-04-10 2001-10-16 Hitachi Medical Corp プローブ装置
JP2007111407A (ja) * 2005-10-24 2007-05-10 Shimadzu Corp 光生体イメージング装置のマルチプローブホルダー
JP2007236963A (ja) * 2007-04-25 2007-09-20 Hitachi Medical Corp プローブ装置
JP2009077841A (ja) * 2007-09-26 2009-04-16 Shimadzu Corp ホルダ及びこれに用いる光生体測定装置
JP2010115252A (ja) * 2008-11-11 2010-05-27 Shimadzu Corp ホルダー
JP2010188155A (ja) * 2010-04-22 2010-09-02 Hitachi Ltd 生体光計測装置およびそれに用いる被検体装着具

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