WO2012128508A3 - 광견병 바이러스를 중화시킬 수 있는 결합 분자 - Google Patents
광견병 바이러스를 중화시킬 수 있는 결합 분자 Download PDFInfo
- Publication number
- WO2012128508A3 WO2012128508A3 PCT/KR2012/001902 KR2012001902W WO2012128508A3 WO 2012128508 A3 WO2012128508 A3 WO 2012128508A3 KR 2012001902 W KR2012001902 W KR 2012001902W WO 2012128508 A3 WO2012128508 A3 WO 2012128508A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- rabies virus
- binding molecules
- neutralizing
- molecules capable
- animals
- Prior art date
Links
- 241000711798 Rabies lyssavirus Species 0.000 title abstract 4
- 230000003472 neutralizing effect Effects 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000282421 Canidae Species 0.000 abstract 1
- 241000282472 Canis lupus familiaris Species 0.000 abstract 1
- 241000282375 Herpestidae Species 0.000 abstract 1
- 241000266847 Mephitidae Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Abstract
본 발명은 광견병 바이러스를 중화시킬 수 있는 결합 분자에 관한 것으로, 더욱 상세하게 본 발명의 결합 분자는 개, 소, 몽구스, 박쥐, 스컹크 및 늑대와 같은 개체에서 유래한 광견병 바이러스를 대상으로 중화하는 능력을 가지고 있으므로, 광범위한 개체에서 유래한 광견병 바이러스에 감염된 환자를 치료하는데 유용하게 이용될 수 있다.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201280013315.9A CN103492419B (zh) | 2011-03-18 | 2012-03-16 | 可中和狂犬病病毒的结合分子 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2011-0024332 | 2011-03-18 | ||
KR20110024332 | 2011-03-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012128508A2 WO2012128508A2 (ko) | 2012-09-27 |
WO2012128508A3 true WO2012128508A3 (ko) | 2012-12-27 |
Family
ID=46879865
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2012/001902 WO2012128508A2 (ko) | 2011-03-18 | 2012-03-16 | 광견병 바이러스를 중화시킬 수 있는 결합 분자 |
Country Status (3)
Country | Link |
---|---|
KR (1) | KR101388680B1 (ko) |
CN (1) | CN103492419B (ko) |
WO (1) | WO2012128508A2 (ko) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2537345B2 (ja) * | 1984-04-25 | 1996-09-25 | トランスジ−ン ソシエテ アノニム | 狂犬病に対するワクチン及びその製造法 |
JP2004528803A (ja) * | 2000-05-16 | 2004-09-24 | トーマス・ジェファーソン・ユニバーシティー | 狂犬病ウイルス特異的ヒトモノクローナル中和抗体及び核酸及び関連する方法 |
KR20070044807A (ko) * | 2004-05-27 | 2007-04-30 | 크루셀 홀란드 비.브이. | 광견병 바이러스를 중화시킬 수 있는 결합 분자 및 그 용도 |
KR20100006868A (ko) * | 2008-07-10 | 2010-01-22 | 대한민국(관리부서 : 농림수산식품부 국립수의과학검역원) | 면역크로마토그라피를 이용한 광견병 항체 신속 검출진단키트 및 면역크로마토그라피를 이용한 광견병 항체진단방법 |
JP2010085126A (ja) * | 2008-09-29 | 2010-04-15 | Adtec Kk | 狂犬病ウイルス中和抗体価判定具および狂犬病ウイルス中和抗体価の測定方法 |
JP2011050269A (ja) * | 2009-08-31 | 2011-03-17 | Evec Inc | 狂犬病ウイルスに対するヒト抗体ならびにその医薬組成物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1355253A (zh) * | 2000-11-29 | 2002-06-26 | 中国预防医学科学院病毒学研究所 | 人源抗狂犬病毒中和性基因工程抗体 |
CN101100663B (zh) * | 2006-07-05 | 2011-08-24 | 华北制药集团新药研究开发有限责任公司 | 重组人抗狂犬病毒单克隆抗体的制备方法 |
CN101560255B (zh) * | 2009-04-22 | 2012-05-23 | 南京医科大学 | 抗狂犬病病毒单克隆抗体及其应用 |
-
2012
- 2012-03-16 KR KR1020120026835A patent/KR101388680B1/ko active IP Right Grant
- 2012-03-16 WO PCT/KR2012/001902 patent/WO2012128508A2/ko active Application Filing
- 2012-03-16 CN CN201280013315.9A patent/CN103492419B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2537345B2 (ja) * | 1984-04-25 | 1996-09-25 | トランスジ−ン ソシエテ アノニム | 狂犬病に対するワクチン及びその製造法 |
JP2004528803A (ja) * | 2000-05-16 | 2004-09-24 | トーマス・ジェファーソン・ユニバーシティー | 狂犬病ウイルス特異的ヒトモノクローナル中和抗体及び核酸及び関連する方法 |
KR20070044807A (ko) * | 2004-05-27 | 2007-04-30 | 크루셀 홀란드 비.브이. | 광견병 바이러스를 중화시킬 수 있는 결합 분자 및 그 용도 |
KR20100006868A (ko) * | 2008-07-10 | 2010-01-22 | 대한민국(관리부서 : 농림수산식품부 국립수의과학검역원) | 면역크로마토그라피를 이용한 광견병 항체 신속 검출진단키트 및 면역크로마토그라피를 이용한 광견병 항체진단방법 |
JP2010085126A (ja) * | 2008-09-29 | 2010-04-15 | Adtec Kk | 狂犬病ウイルス中和抗体価判定具および狂犬病ウイルス中和抗体価の測定方法 |
JP2011050269A (ja) * | 2009-08-31 | 2011-03-17 | Evec Inc | 狂犬病ウイルスに対するヒト抗体ならびにその医薬組成物 |
Also Published As
Publication number | Publication date |
---|---|
CN103492419A (zh) | 2014-01-01 |
KR20120107050A (ko) | 2012-09-28 |
WO2012128508A2 (ko) | 2012-09-27 |
KR101388680B1 (ko) | 2014-04-28 |
CN103492419B (zh) | 2015-11-25 |
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