WO2012111539A1 - Seringue - Google Patents

Seringue Download PDF

Info

Publication number
WO2012111539A1
WO2012111539A1 PCT/JP2012/053041 JP2012053041W WO2012111539A1 WO 2012111539 A1 WO2012111539 A1 WO 2012111539A1 JP 2012053041 W JP2012053041 W JP 2012053041W WO 2012111539 A1 WO2012111539 A1 WO 2012111539A1
Authority
WO
WIPO (PCT)
Prior art keywords
barrel
syringe
needle
piston
connecting portion
Prior art date
Application number
PCT/JP2012/053041
Other languages
English (en)
Japanese (ja)
Inventor
三喜夫 渕上
Original Assignee
有限会社フチガミ器械
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 有限会社フチガミ器械 filed Critical 有限会社フチガミ器械
Priority to JP2012557920A priority Critical patent/JPWO2012111539A1/ja
Publication of WO2012111539A1 publication Critical patent/WO2012111539A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513—Piston constructions to improve sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31516—Piston or piston-rod constructions, e.g. connection of piston with piston-rod reducing dead-space in the syringe barrel after delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31518—Piston or piston-rod constructions, e.g. connection of piston with piston-rod designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3134—Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula

Definitions

  • the present invention relates to a syringe, and particularly to a syringe that is suitable for small-sized and experimental animals.
  • a syringe In order to administer a drug solution to small and experimental animals, a syringe is often used not only for parenteral administration but also for oral administration.
  • a syringe is composed of a barrel having a tip needle connection portion formed in a small diameter and a plunger having a piston fitted to the inner surface of the barrel formed at the tip.
  • the drug solution is originally low in dosage, even a slight error may deviate from the acceptable range for animals, hinder the experiment, and the demand is low, so it is generally expensive. Therefore, it is required to be administered with as little amount as possible with high accuracy.
  • Patent Document 1 the needle connecting portion is referred to as a nozzle 24, and the protruding portion is referred to as a plunger tip 36.
  • an object of the present invention is to provide a syringe capable of discharging a small amount of a chemical solution with higher accuracy and without waste than a conventional syringe.
  • the syringe of the present invention is A barrel body having a substantially uniform inner diameter in the axial direction, and a barrel having a needle connecting portion connected to one end of the barrel body;
  • a syringe comprising a piston fitted to the inner surface of the barrel, and a plunger having a rod connected to the piston and reciprocating in the axial direction within the barrel.
  • a taper that gradually narrows linearly until the inner surface of the needle connecting portion reaches the open end;
  • the piston is connected to the rod on the rear side and can be fitted to the inner surface of the barrel body, and the linear taper is connected to the front of the disk portion and substantially complementary to the inner surface of the needle connecting portion.
  • the needle of the needle connection portion is not limited to a pointed tip and can be pierced into a muscle or a blood vessel, but also includes a tip non-sharp tubule called an oral sonde.
  • the chemical solution is filled in the barrel in front of the disc portion, and as the plunger is pushed in, the disc portion moves forward together with the shot portion, and the chemical solution is discharged from the needle connection portion. Since the inner surface of the needle connecting portion is tapered until reaching the opening end, the chemical solution can be discharged from the opening end in a minute amount with high accuracy. Moreover, since the shot portion has a taper shape complementary to the inner surface of the needle connection portion, the needle connection portion is not blocked until the tip of the shot portion reaches the opening end of the needle connection portion.
  • the shot portion has an extremely small outer diameter at the tip, but has an outer diameter close to that of the disk portion at the proximal end, and thus has sufficient mechanical strength.
  • the barrel body preferably has an annular relief that fits loosely with the disc portion just before the needle connection.
  • the shot part is preferably slightly longer than the needle connection part. Thereby, it can prevent that a chemical
  • the taper rate of the inner surface of the needle connecting portion is preferably 3/100 to 10/100. If the taper ratio is less than 3/100, the above action is poor, and if it exceeds 10/100, it becomes difficult to discharge.
  • a preferable standard capacity of a syringe to which the present invention is applied is 0.1 mL or more and 1 mL or less.
  • the chemical solution can be administered with high accuracy and the chemical solution need not be wasted.
  • the shot part has high mechanical strength, it is hard to break and has excellent durability.
  • the syringe 1 includes a barrel 2 and a plunger 3 and is used with an injection needle (oral sonde) 4 attached thereto in order to administer a drug solution of 0.5 mL or less.
  • the barrel 2 has a cylindrical barrel body 5 having a uniform inner diameter in the axial direction, and a hollow frustum shape continuous with one end of the barrel body 5, and has a needle connection portion 6 having an open end surface.
  • the inner surface of the needle connecting portion 6 has an inner diameter smaller than the inner diameter of the barrel main body 5 at the base end connected to the barrel main body 5, and gradually decreases linearly at a ratio of 6/100 toward the opening end surface ( Taper).
  • the plunger 3 comprises a rod 7 for connecting the piston 7 and the piston 7 to reciprocate the piston 7 in the barrel 2 in the axial direction.
  • the piston 7 includes a disc-shaped disk portion 71 having an outer surface that is coupled to the inner surface of the barrel main body 5 by connecting the rod 8 to the rear, and a shot portion 72 that continues to the front of the disk portion 71.
  • the outer surface of the shot portion 72 has a tapered shape that is substantially complementary to the inner surface of the needle connecting portion 6. However, the outer surface of the shot portion 72 extends in the axial direction slightly longer than the axial length of the inner surface of the needle connecting portion 6.
  • the rod 8 forms a cylindrical portion 82 whose cross section is uniform in the axial direction except that a disc-shaped head 81 having a diameter sufficiently larger than the inner diameter of the barrel body 5 is integrally formed at the rear end. .
  • the syringe 1 When the plunger 3 is retracted, the syringe 1 omits the needle 4 and forms a space S inside the barrel 2 in front of the disk portion 71 as shown in FIG. Further, when the plunger 3 is moved forward as indicated by an imaginary line, the disk portion 71 stops when it is engaged with the step between the needle connecting portion 6 and the barrel body 5 as shown in FIG. At the same time, the outer surface of the shot portion 72 is fitted to the inner surface of the needle connection portion 6, and the tip of the shot portion 72 slightly protrudes from the opening end surface of the needle connection portion 6.
  • the needle 4 When using the syringe 1, the needle 4 is attached to the needle connection portion 6, the needle 4 is inserted into a medicine bottle (not shown), and the plunger 3 is retracted to fill the space S with the chemical solution. . Then, the needle 4 is inserted into the body of the subject animal (not shown), and the plunger 3 is advanced. As it is pushed in, the disk part 71 moves forward together with the shot part 72, and the drug solution is administered from the needle connecting part 6 to the target animal via the inside of the needle. Since the outer surface of the needle connecting portion 6 has a truncated cone shape, the needle 4 is steadily fixed.
  • the needle connecting portion 6 is blocked until the tip of the shot portion 72 exceeds the opening end surface of the needle connecting portion 6. None do. And when the front-end
  • the shot part 72 has an extremely small outer diameter at the tip, but has an outer diameter close to that of the disk part at the base end, and therefore has sufficient mechanical strength.
  • Embodiment 2 The syringe of the second embodiment is composed of the same and similar components as the syringe 1 of the first embodiment, except that the shape of the barrel 12, particularly the barrel body 15, is slightly different from the barrel body 5 of the first embodiment. .
  • the inner diameter of the barrel main body 15 is uniform in the axial direction from the rear end that is the receiving port of the plunger 3 to the vicinity of the needle connecting portion 6, but as shown in FIG. Immediately before, it spreads slightly in an annular shape, and a relief 15a is formed.
  • the chemical liquid is completely discharged, and at the same time, the disk portion 71 fits into the relief 15a and stabilizes, and the return of the plunger 3 due to the reaction force received from the inner surface of the needle connecting portion 16 is prevented.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention vise à fournir une seringue pouvant injecter une petite quantité de médicament liquide de manière plus précise et plus utile qu'une seringue classique. L'invention concerne par conséquent une seringue qui comprend : un corps (2) comprenant un corps principal de corps (5) ayant un diamètre interne constant dans une direction axiale de celui-ci et une partie de connexion d'aiguille (6) s'étendant d'une extrémité du corps principal de corps (5) ; et un plongeur (3) comprenant un piston (7) ajusté dans le corps (2) et une tige s'étendant depuis le piston pour entraîner un mouvement de va-et-vient du piston (7) dans le corps (2) dans la direction axiale, la seringue étant caractérisée en ce que : la surface intérieure de la partie de connexion de l'aiguille (6) est conique, et le piston (7) comprend une partie disque connectée au niveau d'un côté arrière de la tige et ajustée dans le corps principal de corps (5) et une partie destinée à la charge s'étendant d'un côté avant de la partie disque et ayant une forme correspondant à celle de la partie de connexion d'aiguille (6).
PCT/JP2012/053041 2011-02-17 2012-02-10 Seringue WO2012111539A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2012557920A JPWO2012111539A1 (ja) 2011-02-17 2012-02-10 注射器

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011-031906 2011-02-17
JP2011031906 2011-02-17

Publications (1)

Publication Number Publication Date
WO2012111539A1 true WO2012111539A1 (fr) 2012-08-23

Family

ID=46672464

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2012/053041 WO2012111539A1 (fr) 2011-02-17 2012-02-10 Seringue

Country Status (2)

Country Link
JP (1) JPWO2012111539A1 (fr)
WO (1) WO2012111539A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019003358A1 (fr) 2017-06-28 2019-01-03 日本全薬工業株式会社 Outil d'administration de liquide
EP2723673B1 (fr) * 2011-06-24 2020-01-22 Heidi Hall Mors et système pour envoyer une substance visqueuse et/ou liquide dans la bouche d'un animal
JP2020150998A (ja) * 2019-03-18 2020-09-24 住友ベークライト株式会社 シリンジ

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3672369A (en) * 1969-12-18 1972-06-27 Sherwood Medical Ind Inc Hypodermic syringe
JPS57501762A (fr) * 1980-08-29 1982-10-07
JP2005205121A (ja) * 2003-12-26 2005-08-04 Jm Trust Co Ltd 携帯用噴射注入具

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3672369A (en) * 1969-12-18 1972-06-27 Sherwood Medical Ind Inc Hypodermic syringe
JPS57501762A (fr) * 1980-08-29 1982-10-07
JP2005205121A (ja) * 2003-12-26 2005-08-04 Jm Trust Co Ltd 携帯用噴射注入具

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2723673B1 (fr) * 2011-06-24 2020-01-22 Heidi Hall Mors et système pour envoyer une substance visqueuse et/ou liquide dans la bouche d'un animal
WO2019003358A1 (fr) 2017-06-28 2019-01-03 日本全薬工業株式会社 Outil d'administration de liquide
JP2020150998A (ja) * 2019-03-18 2020-09-24 住友ベークライト株式会社 シリンジ
JP7259433B2 (ja) 2019-03-18 2023-04-18 住友ベークライト株式会社 シリンジ

Also Published As

Publication number Publication date
JPWO2012111539A1 (ja) 2014-07-07

Similar Documents

Publication Publication Date Title
US7785292B2 (en) Injection device
US5643211A (en) Nozzle assembly having a frangible plunger
US8690825B2 (en) Safety syringe
US8617099B2 (en) Injection device plunger auto-disable
US20090137949A1 (en) Needle-free injection device with nozzle auto-disable
MXPA03008268A (es) Inyector con diluyente de seguridad pre-cargado.
WO2006105006A3 (fr) Seringue de surete
US11433185B2 (en) Injection device
US8690837B2 (en) Mixing device for a two-chamber ampoule
JPH02185261A (ja) 注射器
US20090054850A1 (en) Pusher with a coupling element
WO2006135616A3 (fr) Ensemble aiguille pour corps de seringue multiples
WO2012111539A1 (fr) Seringue
JP6967973B2 (ja) 薬剤送達装置用のピストンワッシャおよびこのようなピストンワッシャを組み込んだ薬剤送達装置
US20140088500A1 (en) Safety syringe
US10933194B2 (en) Syringe for and method of delivering a volume of solution
SK500382010A3 (sk) Trojkomorový automatický injektor
US20090131879A1 (en) Safety disposable syringe
US20180085536A1 (en) Locking Device for a Syringe
EP1813301A1 (fr) Seringue hypodermique de sécurité
CN210145216U (zh) 用于粘稠药液的注射器
US20210128817A1 (en) Needle unit with biostatic chamber
KR20210133245A (ko) 다기능 바늘 홀더 및 리테이너 링 조립체를 가지는 주사기
US20240131261A1 (en) Low Dead Volume Adaptor for a Syringe
CN215741008U (zh) 自毁式注射器

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12747178

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2012557920

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 12747178

Country of ref document: EP

Kind code of ref document: A1