WO2012064150A3 - 벤프로페린 유도체를 유효성분으로 함유하는 혈관신생-관련 질환의 예방 및 치료용 조성물 - Google Patents

벤프로페린 유도체를 유효성분으로 함유하는 혈관신생-관련 질환의 예방 및 치료용 조성물 Download PDF

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WO2012064150A3
WO2012064150A3 PCT/KR2011/008625 KR2011008625W WO2012064150A3 WO 2012064150 A3 WO2012064150 A3 WO 2012064150A3 KR 2011008625 W KR2011008625 W KR 2011008625W WO 2012064150 A3 WO2012064150 A3 WO 2012064150A3
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preventing
related diseases
angiogenesis
composition
active ingredients
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French (fr)
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WO2012064150A2 (ko
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권병목
한동초
신대섭
한영민
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한국생명공학연구원
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Priority to EP11839421.2A priority Critical patent/EP2638910B1/en
Priority to JP2013538655A priority patent/JP5878928B2/ja
Publication of WO2012064150A2 publication Critical patent/WO2012064150A2/ko
Publication of WO2012064150A3 publication Critical patent/WO2012064150A3/ko
Priority to US13/891,837 priority patent/US8716288B2/en

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Abstract

본 발명은 벤프로페린(benproperine) 유도체의 암 및 혈관신생-관련 질환의 예방 및 치료용 약학적 조성물에 관한 것이다. 본 발명의 벤프로페린 유도체 및 이의 약학적으로 허용가능한 염은 암세포의 이동을 억제하고 혈관내피세포의 혈관형성을 저해함으로써 항암제로서 뿐만 아니라, 당뇨병성 망막증, 각막 이식 거부 등과 같이 비정상적 혈관신생으로 야기되는 질환의 예방 및 치료에 유용하게 사용될 수 있다.
PCT/KR2011/008625 2010-11-11 2011-11-11 벤프로페린 유도체를 유효성분으로 함유하는 혈관신생-관련 질환의 예방 및 치료용 조성물 WO2012064150A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP11839421.2A EP2638910B1 (en) 2010-11-11 2011-11-11 Composition comprising benproperine derivatives as active ingredients for preventing and treating angiogenesis-related diseases
JP2013538655A JP5878928B2 (ja) 2010-11-11 2011-11-11 ベンプロペリン誘導体を有効成分として含有する、血管新生関連疾患の予防及び治療用組成物
US13/891,837 US8716288B2 (en) 2010-11-11 2013-05-10 Composition comprising benproperine derivatives as active ingredients for preventing and treating angiogenesis-related diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2010-0112343 2010-11-11
KR20100112343 2010-11-11

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/891,837 Continuation-In-Part US8716288B2 (en) 2010-11-11 2013-05-10 Composition comprising benproperine derivatives as active ingredients for preventing and treating angiogenesis-related diseases

Publications (2)

Publication Number Publication Date
WO2012064150A2 WO2012064150A2 (ko) 2012-05-18
WO2012064150A3 true WO2012064150A3 (ko) 2012-09-07

Family

ID=46051454

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/008625 WO2012064150A2 (ko) 2010-11-11 2011-11-11 벤프로페린 유도체를 유효성분으로 함유하는 혈관신생-관련 질환의 예방 및 치료용 조성물

Country Status (5)

Country Link
US (1) US8716288B2 (ko)
EP (1) EP2638910B1 (ko)
JP (1) JP5878928B2 (ko)
KR (1) KR101323728B1 (ko)
WO (1) WO2012064150A2 (ko)

Families Citing this family (14)

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US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
CN103626722B (zh) * 2012-08-27 2016-06-01 天津药物研究院 一氧化氮供体型降血糖化合物、其制备方法和用途
CN104784122A (zh) * 2014-01-20 2015-07-22 广东东阳光药业有限公司 一种包含苯丙哌林的固体制剂
KR20160041746A (ko) * 2014-10-07 2016-04-18 한국생명공학연구원 (s)-(-)-벤프로페린을 포함하는 암 예방 또는 치료용 조성물
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
JP7111390B2 (ja) * 2018-05-04 2022-08-02 ブイエスファーマテック 癌細胞の遊走及び浸潤抑制を介した癌転移抑制剤
CN108752290B (zh) * 2018-06-27 2021-05-28 大连万福制药有限公司 一种绿色合成磷酸苯丙哌林中间体的方法
WO2021174475A1 (en) * 2020-03-05 2021-09-10 Givaudan Sa Organic compounds
KR102623917B1 (ko) * 2021-07-16 2024-01-12 한국생명공학연구원 암 세포의 이동과 침윤 억제를 통한 암 전이 억제제
KR20230081285A (ko) 2021-11-30 2023-06-07 주식회사 브이에스팜텍 고순도의 1-(1-(2-벤질페녹시)프로판-2-일)-2-메틸피페리딘 단일 이성질체의 제조방법
WO2023147852A1 (en) 2022-02-02 2023-08-10 Symrise Ag Compositions (iii)

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Also Published As

Publication number Publication date
WO2012064150A2 (ko) 2012-05-18
EP2638910B1 (en) 2017-07-12
US8716288B2 (en) 2014-05-06
EP2638910A4 (en) 2014-04-16
JP5878928B2 (ja) 2016-03-08
EP2638910A2 (en) 2013-09-18
JP2013544815A (ja) 2013-12-19
US20130245068A1 (en) 2013-09-19
KR20120050918A (ko) 2012-05-21
KR101323728B1 (ko) 2013-10-31

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