WO2011059189A3 - Méthode d'identification de cellules souches mésenchymateuses par emploi d'un anticorps anti-tm4sf1 et composition - Google Patents

Méthode d'identification de cellules souches mésenchymateuses par emploi d'un anticorps anti-tm4sf1 et composition Download PDF

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Publication number
WO2011059189A3
WO2011059189A3 PCT/KR2010/007396 KR2010007396W WO2011059189A3 WO 2011059189 A3 WO2011059189 A3 WO 2011059189A3 KR 2010007396 W KR2010007396 W KR 2010007396W WO 2011059189 A3 WO2011059189 A3 WO 2011059189A3
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WO
WIPO (PCT)
Prior art keywords
mesenchymal stem
stem cells
identifying
tm4sf1
composition
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PCT/KR2010/007396
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English (en)
Korean (ko)
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WO2011059189A2 (fr
Inventor
김호언
배소현
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(주)에이프로젠
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Application filed by (주)에이프로젠 filed Critical (주)에이프로젠
Publication of WO2011059189A2 publication Critical patent/WO2011059189A2/fr
Publication of WO2011059189A3 publication Critical patent/WO2011059189A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne une méthode d'identification ou de séparation de cellules souches mésenchymateuses par emploi d'une protéine TM4SF1 spécifiquement exprimée dans les cellules souches mésenchymateuses. Plus spécifiquement, la présente invention concerne une composition contenant un anticorps anti-TM4SF1 pour l'identification ou la séparation de cellules souches mésenchymateuses, et une puce à protéines et un kit d'identification de cellules souches mésenchymateuses contenant un anticorps anti-TM4SF1. En outre, la présente invention concerne une méthode d'identification de cellules souches mésenchymateuses par emploi d'un anticorps anti-TM4SF1, ainsi qu'une méthode de séparation et de purification desdites cellules souches.
PCT/KR2010/007396 2009-11-13 2010-10-27 Méthode d'identification de cellules souches mésenchymateuses par emploi d'un anticorps anti-tm4sf1 et composition WO2011059189A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2009-0109863 2009-11-13
KR1020090109863A KR101168224B1 (ko) 2009-11-13 2009-11-13 항-ｔｍ4ｓｆ1 항체를 이용한 중간엽줄기세포 동정방법 및 그 조성물

Publications (2)

Publication Number Publication Date
WO2011059189A2 WO2011059189A2 (fr) 2011-05-19
WO2011059189A3 true WO2011059189A3 (fr) 2011-09-29

Family

ID=43992179

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/007396 WO2011059189A2 (fr) 2009-11-13 2010-10-27 Méthode d'identification de cellules souches mésenchymateuses par emploi d'un anticorps anti-tm4sf1 et composition

Country Status (2)

Country Link
KR (1) KR101168224B1 (fr)
WO (1) WO2011059189A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180059109A1 (en) * 2016-08-31 2018-03-01 Meridigen Biotech Co., Ltd. Method of distinguishing mesenchymal stem cells and method of determining purity of mesenchymal stem cells
WO2019015696A2 (fr) * 2017-07-17 2019-01-24 同济大学苏州研究院 Nouvelle cible pour traiter le cancer
CN109265546B (zh) * 2017-07-17 2022-05-24 同济大学苏州研究院 用于治疗癌症的新靶标
CN109342739A (zh) * 2018-11-27 2019-02-15 上海科医联创生物科技有限公司 一种鉴定间充质干细胞纯度的方法

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ANDREW, C. ET AL., J. CELL. BIOCHEM., vol. 89, no. 1, 2003, pages 56 - 66 *
BAE, S. ET AL., CELL TISSUE RES., vol. 335, no. 3, March 2009 (2009-03-01), pages 565 - 573 *
KIM, Y. ET AL., PFLUGERS ARCH.-EUR J PHYSIOL, vol. 455, no. 2, 2007, pages 283 - 296 *
SHIN, S. ET AL., CANCER RESEARCH, 7 April 2009 (2009-04-07) *
WAGNER, W. ET AL., EXPERIMENTAL HEMATOLOGY, vol. 33, 2005, pages 1402 - 1416 *

Also Published As

Publication number Publication date
WO2011059189A2 (fr) 2011-05-19
KR101168224B1 (ko) 2012-07-24
KR20110053059A (ko) 2011-05-19

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