WO2011059189A3 - Method for identifying mesenchymal stem cells by using an anti-tm4sf1 antibody and composition thereof - Google Patents

Method for identifying mesenchymal stem cells by using an anti-tm4sf1 antibody and composition thereof Download PDF

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Publication number
WO2011059189A3
WO2011059189A3 PCT/KR2010/007396 KR2010007396W WO2011059189A3 WO 2011059189 A3 WO2011059189 A3 WO 2011059189A3 KR 2010007396 W KR2010007396 W KR 2010007396W WO 2011059189 A3 WO2011059189 A3 WO 2011059189A3
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WO
WIPO (PCT)
Prior art keywords
mesenchymal stem
stem cells
identifying
tm4sf1
composition
Prior art date
Application number
PCT/KR2010/007396
Other languages
French (fr)
Korean (ko)
Other versions
WO2011059189A2 (en
Inventor
김호언
배소현
Original Assignee
(주)에이프로젠
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by (주)에이프로젠 filed Critical (주)에이프로젠
Publication of WO2011059189A2 publication Critical patent/WO2011059189A2/en
Publication of WO2011059189A3 publication Critical patent/WO2011059189A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to a method for identifying or separating mesenchymal stem cells by using a TM4SF1 protein specifically expressed in the mesenchymal stem cells. More specifically, the present invention provides an anti-TM4SF1 containing composition for identifying or separating mesenchymal stem cells, and a mesenchymal stem cell identifying kit and protein chip containing an anti-TM4SF1 antibody. Further, the present invention provides a method for identifying mesenchymal stem cells by using an anti-TM4SF1 antibody and a separation and purification method of the same.
PCT/KR2010/007396 2009-11-13 2010-10-27 Method for identifying mesenchymal stem cells by using an anti-tm4sf1 antibody and composition thereof WO2011059189A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2009-0109863 2009-11-13
KR1020090109863A KR101168224B1 (en) 2009-11-13 2009-11-13 Method for identification of mesenchymal stem cells using anti-TM4SF1 antibody and composition for it

Publications (2)

Publication Number Publication Date
WO2011059189A2 WO2011059189A2 (en) 2011-05-19
WO2011059189A3 true WO2011059189A3 (en) 2011-09-29

Family

ID=43992179

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/007396 WO2011059189A2 (en) 2009-11-13 2010-10-27 Method for identifying mesenchymal stem cells by using an anti-tm4sf1 antibody and composition thereof

Country Status (2)

Country Link
KR (1) KR101168224B1 (en)
WO (1) WO2011059189A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI689589B (en) * 2016-08-31 2020-04-01 宣捷細胞生物製藥股份有限公司 Method of distinguishing mesenchymal stem cells and method of determining purity of mesenchymal stem cells
CN109265546B (en) * 2017-07-17 2022-05-24 同济大学苏州研究院 Novel targets for the treatment of cancer
WO2019015696A2 (en) * 2017-07-17 2019-01-24 同济大学苏州研究院 New target for treating cancer
CN109342739A (en) * 2018-11-27 2019-02-15 上海科医联创生物科技有限公司 A method of identification mescenchymal stem cell purity

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ANDREW, C. ET AL., J. CELL. BIOCHEM., vol. 89, no. 1, 2003, pages 56 - 66 *
BAE, S. ET AL., CELL TISSUE RES., vol. 335, no. 3, March 2009 (2009-03-01), pages 565 - 573 *
KIM, Y. ET AL., PFLUGERS ARCH.-EUR J PHYSIOL, vol. 455, no. 2, 2007, pages 283 - 296 *
SHIN, S. ET AL., CANCER RESEARCH, 7 April 2009 (2009-04-07) *
WAGNER, W. ET AL., EXPERIMENTAL HEMATOLOGY, vol. 33, 2005, pages 1402 - 1416 *

Also Published As

Publication number Publication date
WO2011059189A2 (en) 2011-05-19
KR20110053059A (en) 2011-05-19
KR101168224B1 (en) 2012-07-24

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